The University of Queensland

Sleepless nights: The total synthesis of the anticancer australian rainforest polyketide EBC-23

Williams, Craig M. (2014). Sleepless nights: The total synthesis of the anticancer australian rainforest polyketide EBC-23. Strategies and Tactics in Organic Synthesis. (pp. 249-270) edited by Michael Harmata. Maryland Heights, MO United States: Academic Press. doi: 10.1016/B978-0-12-417185-5.00011-9

The story behind the total synthesis of Vibsanin E and 5-epi-Vibsanin E

Williams, Craig M. (2012). The story behind the total synthesis of Vibsanin E and 5-epi-Vibsanin E. Strategies and tactics in organic synthesis. (pp. 395-412) edited by M. Harmata. San Diego, CA, United States: Academic Press (Elsevier). doi: 10.1016/B978-0-12-386540-3.00017-4

Silver alkyls, alkenyls, aryls, and alkynyls in organic synthesis

Pouwer, Rebecca H. and Williams, Craig M. (2010). Silver alkyls, alkenyls, aryls, and alkynyls in organic synthesis. Silver in organic chemistry. (pp. 1-41) edited by Michael Harmata. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9780470597521.ch1

Product Class 10: Acridin-9(10H)-ones and Related Systems

Prager, R.H. and Williams, C.M. (2005). Product Class 10: Acridin-9(10H)-ones and Related Systems. Science of Synthesis: Category 2, Hetarenes and Related Ring Systems. (pp. 1029-1064) edited by Black, D. StC.. New York: Thieme. doi: 10.1055/sos-SD-015-01714

Product Class 9: Acridines

Prager, R.H. and Williams, C.M. (2005). Product Class 9: Acridines. Science of Synthesis: Category 2, Hetarenes and Related Ring Systems. (pp. 987-1028) edited by Black, D. StC.. New York: Thieme. doi: 10.1055/sos-SD-015-01674

Macrocyclic Copper(II) Complexes as Catalysts for Electrochemically Mediated Atom Transfer

Naher, Masnun, Su, Chuyi, Harmer, Jeffrey R., Williams, Craig M. and Bernhardt, Paul V. (2024). Macrocyclic Copper(II) Complexes as Catalysts for Electrochemically Mediated Atom Transfer. Inorganic Chemistry. doi: 10.1021/acs.inorgchem.4c00311

The (±)-5-Aza[1.0]triblattane Skeleton via Azetine Cycloaddition

Su, Chuyi, Dallaston, Madeleine A., Watson, Renée D., Fahrenhorst-Jones, Tyler, Cameron, Jacob P., Pierens, Gregory K., Bernhardt, Paul V., Savage, G. Paul and Williams, Craig M. (2024). The (±)-5-Aza[1.0]triblattane Skeleton via Azetine Cycloaddition. Organic Letters. doi: 10.1021/acs.orglett.3c03655

seco-1-Azacubane-2-carboxylic acid: derivative scope and comparative biological evaluation

Kong, Dehui, Fahrenhorst-Jones, Tyler, Kuo, Andy, Simmons, Jacinta L., Tan, Lendl, Burns, Jed M., Pierens, Gregory K., Li, Rui, West, Nicholas P., Boyle, Glen M., Smith, Maree T., Savage, G. Paul and Williams, Craig M. (2023). seco-1-Azacubane-2-carboxylic acid: derivative scope and comparative biological evaluation. The Journal of Organic Chemistry, 89 (1), 798-803. doi: 10.1021/acs.joc.3c02333

Reassignment of the Structure of Janthinolide A

Bates, Roderick W., Elyashberg, Mikhail, Kutateladze, Andrei G. and Williams, Craig M. (2023). Reassignment of the Structure of Janthinolide A. European Journal of Organic Chemistry, 26 (44). doi: 10.1002/ejoc.202300910

Penicitone: Structural Reassignment of a Proposed Natural Product Acid Chloride

Novitskiy, Ivan M., Elyashberg, Mikhail, Bates, Roderick W., Kutateladze, Andrei G. and Williams, Craig M. (2023). Penicitone: Structural Reassignment of a Proposed Natural Product Acid Chloride. Organic Letters, 25 (43), 7796-7799. doi: 10.1021/acs.orglett.3c02859

9-Azahomocubane

Fahrenhorst-Jones, Tyler, Marshall, David L., Burns, Jed M., Pierens, Gregory K., Van Meurs, Derek P., Kong, Dehui, Bernhardt, Paul V., Blanksby, Stephen J., Savage, G. Paul, Eaton, Philip E. and Williams, Craig M. (2023). 9-Azahomocubane. Chemistry: A European Journal, 30 (3) e202303133, e202303133. doi: 10.1002/chem.202303133

Arneroma B: Structure reassignment and total synthesis

Deepak, Nashvin Mikhail Singh, Kutateladze, Andrei G., Elyashberg, Mikhail, Williams, Craig M. and Bates, Roderick W. (2023). Arneroma B: Structure reassignment and total synthesis. Tetrahedron, 147 133670, 133670. doi: 10.1016/j.tet.2023.133670

Electrocatalytic atom transfer radical addition with turbocharged organocopper(II) complexes

Naher, Masnun, Su, Chuyi, Harmer, Jeffrey R., Williams, Craig M. and Bernhardt, Paul V. (2023). Electrocatalytic atom transfer radical addition with turbocharged organocopper(II) complexes. Inorganic Chemistry, 62 (38), 15575-15583. doi: 10.1021/acs.inorgchem.3c02106

seco-1-Azacubane-2-carboxylic acid–Amide Bond Comparison to Proline

Fahrenhorst-Jones, Tyler, Kong, Dehui, Burns, Jed M., Pierens, Gregory K., Bernhardt, Paul V., Savage, G. Paul and Williams, Craig M. (2023). seco-1-Azacubane-2-carboxylic acid–Amide Bond Comparison to Proline. The Journal of Organic Chemistry, 88 (18), 12867-12871. doi: 10.1021/acs.joc.3c01264

Cubane and cyclooctatetraene pirfenidones – synthesis and biological evaluation

Liu, Yizhou, Wen Liang, Benjamin Jian, Modhiran, Naphak, Savage, G. Paul, Watterson, Daniel and Williams, Craig M. (2023). Cubane and cyclooctatetraene pirfenidones – synthesis and biological evaluation. Asian Journal of Organic Chemistry, 12 (8) e202300238, 1-7. doi: 10.1002/ajoc.202300238

1-azahomocubane

Fahrenhorst-Jones, Tyler, Marshall, David L., Burns, Jed. M., Pierens, Gregory K., Hormann, Robert E., Fisher, Allison M., Bernhardt, Paul V., Blanksby, Stephen J., Savage, G. Paul, Eaton, Philip E. and Williams, Craig M. (2023). 1-azahomocubane. Chemical Science, 14 (11), 2821-2825. doi: 10.1039/d3sc00001j

Crystal structure of the commercial herbicide, amidosulfuron, in complex with Arabidopsis thaliana acetohydroxyacid synthase

Cheng, Yan, Lonhienne, Thierry, Garcia, Mario. D., Williams, Craig M., Schenk, Gerard and Guddat, Luke W. (2023). Crystal structure of the commercial herbicide, amidosulfuron, in complex with Arabidopsis thaliana acetohydroxyacid synthase. Journal of Agricultural and Food Chemistry, 71 (13), 5117-5126. doi: 10.1021/acs.jafc.2c08528

Kinetico-mechanistic studies on a reactive organocopper(II) complex: Cu–C bond homolysis versus heterolysis

Gonzálvez, Miguel A., Williams, Craig M., Martínez, Manuel and Bernhardt, Paul V. (2023). Kinetico-mechanistic studies on a reactive organocopper(II) complex: Cu–C bond homolysis versus heterolysis. Inorganic Chemistry, 62 (11), 4662-4671. doi: 10.1021/acs.inorgchem.3c00127

Multitargeted opioid ligand discovery as a strategy to retain analgesia and reduce opioid-related adverse effects

Smith, Maree T., Kong, Dehui, Kuo, Andy, Imam, Mohammad Z. and Williams, Craig M. (2023). Multitargeted opioid ligand discovery as a strategy to retain analgesia and reduce opioid-related adverse effects. Journal of Medicinal Chemistry, 66 (6), 3746-3784. doi: 10.1021/acs.jmedchem.2c01695

seco-pregnane glycosides from Australian caustic vine (Cynanchum viminale subsp. australe)

Xue, Yongbo, Savchenko, Andrei I., Agnew-Francis, Kylie A., Miles, Jared A., Holt, Tina, Lu, Hieng, Chow, Sharon, Forster, Paul I., Boyle, Glen M., Ross, Benjamin P., Fischer, Katja, Kutateladze, Andrei G. and Williams, Craig M. (2023). seco-pregnane glycosides from Australian caustic vine (Cynanchum viminale subsp. australe). Journal of Natural Products, 86 (3), 490-497. doi: 10.1021/acs.jnatprod.2c01037

A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase

Jin, Da-Yun, Chen, Xuejie, Liu, Yizhou, Williams, Craig M., Pedersen, Lars C., Stafford, Darrel W. and Tie, Jian-Ke (2023). A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase. Nature Communications, 14 (1) 828, 1-14. doi: 10.1038/s41467-023-36446-8

Structural Reassignment of Two Polyenol Natural Products

Kutateladze, Andrei G., Bates, Roderick W., Elyashberg, Mikhail and Williams, Craig M. (2023). Structural Reassignment of Two Polyenol Natural Products. European Journal of Organic Chemistry, 26 (9) e202201316. doi: 10.1002/ejoc.202201316

Chiral auxiliary-directed site-selective deprotonation of the cubane skeleton

Takebe, Hiyori, Yoshino, Nana, Shimada, Yukako, Williams, Craig M. and Matsubara, Seijiro (2023). Chiral auxiliary-directed site-selective deprotonation of the cubane skeleton. Organic Letters, 25 (1), 27-30. doi: 10.1021/acs.orglett.2c03659

Unearthing the subtleties of rhodium(II)-catalyzed carbenoid cycloadditions to furans with an N-sulfonyl-1,2,3-triazole probe

Bettencourt, Christian J., Krainz, Tanja, Chow, Sharon, Parr, Brendan T., Tracy, William F., Bernhardt, Paul V., Davies, Huw M. L. and Williams, Craig M. (2022). Unearthing the subtleties of rhodium(II)-catalyzed carbenoid cycloadditions to furans with an N-sulfonyl-1,2,3-triazole probe. Organic Letters, 24 (50), 9290-9295. doi: 10.1021/acs.orglett.2c03869

Structural basis of resistance to herbicides that target acetohydroxyacid synthase

Lonhienne, Thierry, Cheng, Yan, Garcia, Mario D., Hu, Shu Hong, Low, Yu Shang, Schenk, Gerhard, Williams, Craig M. and Guddat, Luke W. (2022). Structural basis of resistance to herbicides that target acetohydroxyacid synthase. Nature Communications, 13 (1) 3368, 3368. doi: 10.1038/s41467-022-31023-x

Wasabi (Eutrema japonicum) reduces obesity and blood pressure in diet-induced metabolic syndrome in rats

Thomaz, Fernanda Santos, Tan, Yuen P., Williams, Craig M., Ward, Leigh C., Worrall, Simon and Panchal, Sunil K. (2022). Wasabi (Eutrema japonicum) reduces obesity and blood pressure in diet-induced metabolic syndrome in rats. Foods, 11 (21) 3435, 1-12. doi: 10.3390/foods11213435

Reassignment of improbable natural products identified through chemical principle screening

Elyashberg, Mikhail, Novitskiy, Ivan M., Bates, Roderick W., Kutateladze, Andrei G. and Williams, Craig M. (2022). Reassignment of improbable natural products identified through chemical principle screening. European Journal of Organic Chemistry, 2022 (34) e202200572, 1-9. doi: 10.1002/ejoc.202200572

Design, synthesis and evaluation of alpha lipoic acid derivatives to treat multiple sclerosis-associated central neuropathic pain

Kong, Dehui, Saqer, Alaa A., Carpinelli de Jesus, Matheus, Khan, Nemat, Jones, Alun, Blanchfield, Joanne T., Smith, Maree T. and Williams, Craig M. (2022). Design, synthesis and evaluation of alpha lipoic acid derivatives to treat multiple sclerosis-associated central neuropathic pain. Bioorganic and Medicinal Chemistry, 69 116889, 1-10. doi: 10.1016/j.bmc.2022.116889

Photochemical generation of the 2-azabicyclo[4.2.0]octa-4,7-diene skeleton

Fahrenhorst-Jones, Tyler, Savage, G. Paul and Williams, Craig M. (2022). Photochemical generation of the 2-azabicyclo[4.2.0]octa-4,7-diene skeleton. Australian Journal of Chemistry, 75 (11), 884-887. doi: 10.1071/ch22139

Genome-guided analysis of seven weed species reveals conserved sequence and structural features of key gene targets for herbicide development

Shah, Sarah, Lonhienne, Thierry, Murray, Cody-Ellen, Chen, Yibi, Dougan, Katherine E., Low, Yu Shang, Williams, Craig M., Schenk, Gerhard, Walter, Gimme H., Guddat, Luke W. and Chan, Cheong Xin (2022). Genome-guided analysis of seven weed species reveals conserved sequence and structural features of key gene targets for herbicide development. Frontiers in Plant Science, 13 909073. doi: 10.3389/fpls.2022.909073

Toward the total synthesis of alpkinidine: Michael addition to isoquinolinetrione CE ring-system synthons

Buccini, Marco, Dhoro, Francis, Tham, Louisa, Skelton, Brian W., Williams, Craig M. and Piggott, Matthew J. (2022). Toward the total synthesis of alpkinidine: Michael addition to isoquinolinetrione CE ring-system synthons. ACS Omega, 7 (23), 19093-19105. doi: 10.1021/acsomega.2c02117

Toward the total synthesis of alpkinidine: synthesis of haloquinone CE ring system synthons and attempted nucleophilic bisannulation

Buccini, Marco, Tham, Louisa, Dhoro, Francis, Skelton, Brian W., Williams, Craig M. and Piggott, Matthew J. (2022). Toward the total synthesis of alpkinidine: synthesis of haloquinone CE ring system synthons and attempted nucleophilic bisannulation. ACS Omega, 7 (23), 19080-19092. doi: 10.1021/acsomega.2c02116

Naturally occurring UBIAD1 mutations differentially affect menaquinone biosynthesis and vitamin K‐dependent carboxylation

Chen, Xuejie, Furukawa, Natsuko, Jin, Da‐Yun, Liu, Yizhou, Stafford, Darrel W., Williams, Craig M., Suhara, Yoshitomo and Tie, Jian‐Ke (2022). Naturally occurring UBIAD1 mutations differentially affect menaquinone biosynthesis and vitamin K‐dependent carboxylation. The FEBS Journal, 289 (9), 2613-2627. doi: 10.1111/febs.16291

The (±)-6-Aza[1.0]triblattane skeleton: contraction beyond the Wilder–Culberson ring system

Fahrenhorst-Jones, Tyler, Bernhardt, Paul V., Savage, G. Paul and Williams, Craig M. (2022). The (±)-6-Aza[1.0]triblattane skeleton: contraction beyond the Wilder–Culberson ring system. Organic Letters, 24 (3) acs.orglett.1c04240, 903-906. doi: 10.1021/acs.orglett.1c04240

Analgesic opioid ligand discovery based on nonmorphinan scaffolds derived from natural sources

Smith, Maree T., Kong, Dehui, Kuo, Andy, Imam, Mohammad Z. and Williams, Craig M. (2022). Analgesic opioid ligand discovery based on nonmorphinan scaffolds derived from natural sources. Journal of Medicinal Chemistry, 65 (3) acs.jmedchem.0c01915, 1612-1661. doi: 10.1021/acs.jmedchem.0c01915

Organocopper(II) complexes: new catalysts for carbon–carbon bond formation via electrochemical atom transfer radical addition (eATRA)

Gonzálvez, Miguel A., Su, Chuyi, Williams, Craig M. and Bernhardt, Paul V. (2022). Organocopper(II) complexes: new catalysts for carbon–carbon bond formation via electrochemical atom transfer radical addition (eATRA). Chemical Science, 13 (35), 10506-10511. doi: 10.1039/d2sc03418b

Activation of PKC supports the anticancer activity of tigilanol tiglate and related epoxytiglianes

Cullen, Jason K., Boyle, Glen M., Yap, Pei-Yi, Elmlinger, Stefan, Simmons, Jacinta L., Broit, Natasa, Johns, Jenny, Ferguson, Blake, Maslovskaya, Lidia A., Savchenko, Andrei I., Mirzayans, Paul Malek, Porzelle, Achim, Bernhardt, Paul V., Gordon, Victoria A., Reddell, Paul W., Pagani, Alberto, Appendino, Giovanni, Parsons, Peter G. and Williams, Craig M. (2021). Activation of PKC supports the anticancer activity of tigilanol tiglate and related epoxytiglianes. Scientific Reports, 11 (1) 207, 207. doi: 10.1038/s41598-020-80397-9

Tandem oxidation-dehydrogenation of (hetero)arylated primary alcohols via perruthenate catalysis

Bettencourt, Christian J., Chow, Sharon, Moore, Peter W., Read, Christopher D. G., Jiao, Yanxiao, Bakker, Jan Peter, Zhao, Sheng, Bernhardt, Paul V. and Williams, Craig M. (2021). Tandem oxidation-dehydrogenation of (hetero)arylated primary alcohols via perruthenate catalysis. Australian Journal of Chemistry, 74 (9), 652-659. doi: 10.1071/ch21137

Unmasking inherent chirality within the cubane skeleton

Yoshino, Nana, Kato, Yumi, Shimada, Yukako, Williams, Craig M. and Matsubara, Seijiro (2021). Unmasking inherent chirality within the cubane skeleton. Israel Journal of Chemistry, 61 (7-8), 380-386. doi: 10.1002/ijch.202100013

Comprehensive computational investigation of the Barton–Kellogg reaction for both alkyl and aryl systems

Burns, Jed M., Clark, Timothy and Williams, Craig M. (2021). Comprehensive computational investigation of the Barton–Kellogg reaction for both alkyl and aryl systems. The Journal of Organic Chemistry, 86 (11) acs.joc.1c00506, 1-14. doi: 10.1021/acs.joc.1c00506

Experimental and theoretical approaches for the development of 4H-Chromene derivatives as inhibitors of tyrosinase

Canavieira, Luciana Morais, Brasil, Edikarlos Macedo, Silva, Thiago de Melo e, Borges, Rosivaldo dos Santos, Silva, José Rogério Araújo, Lameira, Jerônimo, Bernhardt, Paul V., Williams, Craig M. and Alves, Cláudio Nahum (2021). Experimental and theoretical approaches for the development of 4H-Chromene derivatives as inhibitors of tyrosinase. Molecular Simulation, 47 (9), 762-770. doi: 10.1080/08927022.2021.1926455

The future of retrosynthesis and synthetic planning: algorithmic, humanistic or the interplay?

Williams, Craig M. and Dallaston, Madeleine A. (2021). The future of retrosynthesis and synthetic planning: algorithmic, humanistic or the interplay?. Australian Journal of Chemistry, 74 (5), 291-326. doi: 10.1071/ch20371

A novel vitamin K derived anticoagulant tolerant to genetic variations of vitamin K epoxide reductase

Chen, Xuejie, Liu, Yizhou, Furukawa, Natsuko, Jin, Da‐Yun, Paul Savage, G., Stafford, Darrel W., Suhara, Yoshitomo, Williams, Craig M. and Tie, Jian‐Ke (2021). A novel vitamin K derived anticoagulant tolerant to genetic variations of vitamin K epoxide reductase. Journal of Thrombosis and Haemostasis, 19 (3), 689-700. doi: 10.1111/jth.15209

Enone-promoted decarboxylation of trans-4-hydroxy-l-proline in flow: a side-by-side comparison to batch

Pilkington, Rowan L., Dallaston, Madeleine A., Savage, G. Paul, Williams, Craig M. and Polyzos, Anastasios (2021). Enone-promoted decarboxylation of trans-4-hydroxy-l-proline in flow: a side-by-side comparison to batch. Reaction Chemistry and Engineering, 6 (3), 486-493. doi: 10.1039/d0re00442a

Corrigendum to: Ranking Oxidant Sensitiveness: A Guide for Synthetic Utility (Chemistry – A European Journal, (2019), 25, 41, (9614-9618), 10.1002/chem.201902036)

Dallaston, Madeleine A., Bettencourt, Christian J., Chow, Sharon, Gebhardt, Joshua, Spangler, Jordan, Johnston, Martin R., Wall, Craig, Brusnahan, Jason S. and Williams, Craig M. (2020). Corrigendum to: Ranking Oxidant Sensitiveness: A Guide for Synthetic Utility (Chemistry – A European Journal, (2019), 25, 41, (9614-9618), 10.1002/chem.201902036). Chemistry - A European Journal, 26 (59) chem.202004223, 13532-13532. doi: 10.1002/chem.202004223

Nonclassical Phenyl Bioisosteres as Effective Replacements in a Series of Novel Open-Source Antimalarials

Tse, Edwin G., Houston, Sevan D., Williams, Craig M., Savage, G. Paul, Rendina, Louis M., Hallyburton, Irene, Anderson, Mark, Sharma, Raman, Walker, Gregory S., Obach, R. Scott and Todd, Matthew H. (2020). Nonclassical Phenyl Bioisosteres as Effective Replacements in a Series of Novel Open-Source Antimalarials. Journal of Medicinal Chemistry, 63 (20) acs.jmedchem.0c00746, 11585-11601. doi: 10.1021/acs.jmedchem.0c00746

Synthetic tigliane intermediates engage thiols to induce potent cell line selective anti‐cancer activity

Chow, Sharon, Krainz, Tanja, Bettencourt, Christian J., Broit, Natasa, Ferguson, Blake, Zhu, Mingzhao, Hull, Kenneth G., Pierens, Gregory K., Bernhardt, Paul V., Parsons, Peter G., Romo, Daniel, Boyle, Glen M. and Williams, Craig M. (2020). Synthetic tigliane intermediates engage thiols to induce potent cell line selective anti‐cancer activity. Chemistry: A European Journal, 26 (59) chem.202003221, 13372-13377. doi: 10.1002/chem.202003221

Herbicides that target acetohydroxyacid synthase are potent inhibitors of the growth of drug resistant Candida auris

Agnew-Francis, Kylie A., Tang, Yu Cheng, Lin, Xin, Low, Yu Shang, Wun, Shun Jie, Kuo, Andy, Elias, S. M. A. Sayeed Ibn, Lonhienne, Thierry G., Condon, Nicholas, Pimentel, Bruna Natalia Alves da Silva, Vergani, Carlos, Smith, Maree T., Fraser, James A., Williams, Craig M. and Guddat, Luke W (2020). Herbicides that target acetohydroxyacid synthase are potent inhibitors of the growth of drug resistant Candida auris. ACS infectious diseases, 6 (11) acsinfecdis.0c00229, 2901-2912. doi: 10.1021/acsinfecdis.0c00229

Squaramides as bioisosteres in contemporary drug design

Agnew-Francis, Kylie A. and Williams, Craig M. (2020). Squaramides as bioisosteres in contemporary drug design. Chemical Reviews, 120 (20) acs.chemrev.0c00416, 11616-11650. doi: 10.1021/acs.chemrev.0c00416

EBC‐232 and 323: a structural conundrum necessitating unification of five in silico prediction and elucidation methods

Maslovskaya, Lidia A., Savchenko, Andrei I., Krenske, Elizabeth H., Chow, Sharon, Holt, Tina, Gordon, Victoria A., Reddell, Paul W., Pierce, Carly J., Parsons, Peter G., Boyle, Glen M., Kutateladze, Andrei G. and Williams, Craig M. (2020). EBC‐232 and 323: a structural conundrum necessitating unification of five in silico prediction and elucidation methods. Chemistry – A European Journal, 26 (51) chem.202001884, 11862-11867. doi: 10.1002/chem.202001884

Cubane, Bicyclo[1.1.1]pentane and Bicyclo[2.2.2]octane: Impact and Thermal Sensitiveness of Carboxyl-, Hydroxymethyl- and Iodo-substituents

Dallaston, Madeleine A., Houston, Sevan D. and Williams, Craig M. (2020). Cubane, Bicyclo[1.1.1]pentane and Bicyclo[2.2.2]octane: Impact and Thermal Sensitiveness of Carboxyl-, Hydroxymethyl- and Iodo-substituents. Chemistry - A European Journal, 26 (52) chem.202001658, 11966-11970. doi: 10.1002/chem.202001658

Structures of fungal and plant acetohydroxyacid synthases

Lonhienne, Thierry, Low, Yu Shang, Garcia, Mario D., Croll, Tristan, Gao, Yan, Wang, Quan, Brillault, Lou, Williams, Craig M., Fraser, James A., McGeary, Ross P., West, Nicholas P., Landsberg, Michael J., Rao, Zihe, Schenk, Gerhard and Guddat, Luke W. (2020). Structures of fungal and plant acetohydroxyacid synthases. Nature, 586 (7828), 317-321+. doi: 10.1038/s41586-020-2514-3

Cubane chirality via substitution of a “hidden” regular tetrahedron

Yoshino, Nana, Kato, Yumi, Mabit, Thibaud, Nagata, Yuuya, Williams, Craig M., Harada, Mei, Muranaka, Atsuya, Uchiyama, Masanobu and Matsubara, Seijiro (2020). Cubane chirality via substitution of a “hidden” regular tetrahedron. Organic Letters, 22 (11) acs.orglett.0c01142, 4083-4087. doi: 10.1021/acs.orglett.0c01142

Kalparinol, a Salvialane (Isodaucane) sesquiterpenoid derived from native Australian dysphania species that suggests a putative biogenetic link to zerumbone

Tan, Yuen Ping, Savchenko, Andrei I., Agnew-Francis, Kylie A., Boyle, Glen M., Bernhardt, Paul V., Fraser, James A. and Williams, Craig M. (2020). Kalparinol, a Salvialane (Isodaucane) sesquiterpenoid derived from native Australian dysphania species that suggests a putative biogenetic link to zerumbone. Journal of Natural Products, 83 (5) acs.jnatprod.9b01039, 1473-1479. doi: 10.1021/acs.jnatprod.9b01039

EBC-342: A novel tetrahydrofuran moiety containing casbane from the Australian rainforest

Maslovskaya, Lidia A., Savchenko, Andrei I., Krenske, Elizabeth H., Chow, Sharon, Gordon, Victoria A., Reddell, Paul W., Pierce, Carly J., Parsons, Peter G., Boyle, Glen M. and Williams, Craig M. (2020). EBC-342: A novel tetrahydrofuran moiety containing casbane from the Australian rainforest. European Journal of Organic Chemistry, 2020 (8), 1042-1045. doi: 10.1002/ejoc.202000017

Humulene diepoxides from the Australian arid zone herb Dysphania: assignment of aged hops constituents

Tan, Yuen Ping, Agnew‐Francis, Kylie A., Hofmann, Julian, Savchenko, Andrei I., Lafontaine, Scott R., Boyle, Glen M., Bernhardt, Paul V., Fraser, James A., Shellhammer, Thomas H. and Williams, Craig M. (2020). Humulene diepoxides from the Australian arid zone herb Dysphania: assignment of aged hops constituents. Chemistry: A European Journal, 26 (7) chem.201904420, 1653-1660. doi: 10.1002/chem.201904420

Rearrangement-free hydroxylation of methylcubanes by a cytochrome P450: the case for dynamical coupling of C–H abstraction and rebound

Sarkar, Md. Raihan, Houston, Sevan D., Savage, G. Paul, Williams, Craig M., Krenske, Elizabeth H., Bell, Stephen G. and De Voss, James J. (2019). Rearrangement-free hydroxylation of methylcubanes by a cytochrome P450: the case for dynamical coupling of C–H abstraction and rebound. Journal of the American Chemical Society, 141 (50) jacs.9b08064, 19688-19699. doi: 10.1021/jacs.9b08064

En route to D-ring inverted phorbol esters

Chow, Sharon, Krainz, Tanja, Bernhardt, Paul V. and Williams, Craig M. (2019). En route to D-ring inverted phorbol esters. Organic Letters, 21 (21) acs.orglett.9b03379, 8761-8764. doi: 10.1021/acs.orglett.9b03379

Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon

Tan, Yuen P., Xue, Yongbo, Savchenko, Andrei I., Houston, Sevan D., Modhiran, Naphak, McMillan, Christopher L. D., Boyle, Glen M., Bernhardt, Paul V., Young, Paul R., Watterson, Daniel and Williams, Craig M. (2019). Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon. Journal of Natural Products, 82 (10) acs.jnatprod.9b00522, 2828-2834. doi: 10.1021/acs.jnatprod.9b00522

1,4-Diazacubane crystal structure rectified as piperazinium

Arachchige, Kasun S. Athukorala, Fahrenhorst-Jones, Tyler, Burns, Jed M., AL-Fayaad, Hydar A., Behera, Jogendra N., Rao, C. N. R., Clegg, Jack K. and Williams, Craig M. (2019). 1,4-Diazacubane crystal structure rectified as piperazinium. Chemical Communications, 55 (78), 11751-11753. doi: 10.1039/c9cc06272f

Contemplating 1,2,4-thiadiazole-inspired cyclic peptide mimics: a computational investigation

Xie, Sida, Bernhardt, Paul V., Gahan, Lawrence R. and Williams, Craig M. (2019). Contemplating 1,2,4-thiadiazole-inspired cyclic peptide mimics: a computational investigation. Australian Journal of Chemistry, 72 (11), 894-899. doi: 10.1071/CH19248

Ranking oxidant sensitiveness: a guide for synthetic utility

Dallaston, Madeleine A., Bettencourt, Christian J., Chow, Sharon, Gebhardt, Joshua, Spangler, Jordan, Johnston, Martin R., Wall, Craig, Brusnahan, Jason S. and Williams, Craig M. (2019). Ranking oxidant sensitiveness: a guide for synthetic utility. Chemistry - A European Journal, 25 (41), 9614-9618. doi: 10.1002/chem.201902036

The cubane paradigm in bioactive molecule discovery: further scope, limitations and the cyclooctatetraene complement

Houston, Sevan D., Fahrenhorst-Jones, Tyler, Xing, Hui, Chalmers, Benjamin A., Sykes, Melissa L., Stok, Jeanette E., Farfan Soto, Clementina, Burns, Jed M., Bernhardt, Paul V., De Voss, James J., Boyle, Glen M., Smith, Maree T., Tsanaktsidis, John, Savage, G. Paul, Avery, Vicky M. and Williams, Craig M. (2019). The cubane paradigm in bioactive molecule discovery: further scope, limitations and the cyclooctatetraene complement. Organic and Biomolecular Chemistry, 17 (28), 6790-6798. doi: 10.1039/c9ob01238a

Thermal and sensitiveness determination of cubanes: towards cubane‐based fuels for infrared countermeasures

Dallaston, Madeleine A., Brusnahan, Jason S., Wall, Craig and Williams, Craig M. (2019). Thermal and sensitiveness determination of cubanes: towards cubane‐based fuels for infrared countermeasures. Chemistry: A European Journal, 25 (35) chem.201901086, 8344-8352. doi: 10.1002/chem.201901086

Determining the necessity of phenyl ring π-character in warfarin

Xing, Hui, Houston, Sevan D., Chen, Xuejie, Jin, Da-Yun, Savage, G. Paul, Tie, Jian-Ke and Williams, Craig M. (2019). Determining the necessity of phenyl ring π-character in warfarin. Bioorganic and Medicinal Chemistry Letters, 29 (15), 1954-1956. doi: 10.1016/j.bmcl.2019.05.039

Reassignments and corroborations of oxo-bridged natural products directed by OSE and DU8+ NMR computation

Kutateladze, Andrei G., Krenske, Elizabeth H. and Williams, Craig M. (2019). Reassignments and corroborations of oxo-bridged natural products directed by OSE and DU8+ NMR computation. Angewandte Chemie International Edition, 58 (21), 7107-7112. doi: 10.1002/anie.201902777

Nitric oxide modulates μ‐opioid receptor function in vitro

Huang, Lillian, Wyse, Bruce D., Williams, Craig M. and Smith, Maree T. (2019). Nitric oxide modulates μ‐opioid receptor function in vitro. Clinical and Experimental Pharmacology and Physiology, 46 (7) 1440-1681.13091, 676-685. doi: 10.1111/1440-1681.13091

Stachyonic acid: a dengue virus inhibitor from Basilicum polystachyon

Tan, Yuen P., Houston, Sevan D., Modhiran, Naphak, Savchenko, Andrei I., Boyle, Glen M., Young, Paul R., Watterson, Daniel and Williams, Craig M. (2019). Stachyonic acid: a dengue virus inhibitor from Basilicum polystachyon. Chemistry – A European Journal, 25 (22) chem.201900591, 5664-5667. doi: 10.1002/chem.201900591

Cyclooctatetraene: a bioactive cubane paradigm complement

Xing, Hui, Houston, Sevan D., Chen, Xuejie, Ghassabian, Sussan, Fahrenhorst-Jones, Tyler, Kuo, Andy, Murray, Cody-Ellen P., Conn, Kyna-Anne, Jaeschke, Kara N., Jin, Da-Yun, Pasay, Cielo, Bernhardt, Paul V., Burns, Jed M., Tsanaktsidis, John, Savage, G. Paul, Boyle, Glen M., De Voss, James J., McCarthy, James, Walter, Gimme H., Burne, Thomas H. J., Smith, Maree T., Tie, Jian-Ke and Williams, Craig M. (2019). Cyclooctatetraene: a bioactive cubane paradigm complement. Chemistry: A European Journal, 25 (11), 2729-2734. doi: 10.1002/chem.201806277

Cyclooctatetraenes through valence isomerization of cubanes: scope and limitations

Houston, Sevan D., Xing, Hui, Bernhardt, Paul V., Vanden Berg, Timothy J., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2019). Cyclooctatetraenes through valence isomerization of cubanes: scope and limitations. Chemistry: A European Journal, 25 (11), 2735-2739. doi: 10.1002/chem.201805124

Cubanes in medicinal chemistry

Reekie, Tristan A., Williams, Craig M., Rendina, Louis M. and Kassiou, Michael (2019). Cubanes in medicinal chemistry. Journal of Medicinal Chemistry, 62 (3) acs.jmedchem.8b00888, 1078-1095. doi: 10.1021/acs.jmedchem.8b00888

Enantioselective synthesis of (R)-2-cubylglycine including unprecedented rhodium mediated C–H insertion of cubane

Houston, Sevan D., Chalmers, Benjamin A., Savage, G. Paul and Williams, Craig M. (2019). Enantioselective synthesis of (R)-2-cubylglycine including unprecedented rhodium mediated C–H insertion of cubane. Organic & Biomolecular Chemistry, 17 (5), 1067-1070. doi: 10.1039/c8ob02959h

New Halimanes from the Australian rainforest plant Croton Insularis

Maslovskaya, Lidia A., Savchenko, Andrei I., Gordon, Victoria A., Reddell, Paul W., Pierce, Carly J., Boyle, Glen M., Parsons, Peter G. and Williams, Craig M. (2019). New Halimanes from the Australian rainforest plant Croton Insularis. European Journal of Organic Chemistry, 2019 (5), 1058-1060. doi: 10.1002/ejoc.201801548

New casbanes and the first trans‐cyclopropane seco‐casbane from the Australian rainforest plant croton insularis

Maslovskaya, Lidiya A., Savchenko, Andrei I., Pierce, Carly J., Boyle, Glen M., Gordon, Victoria A., Reddell, Paul W., Parsons, Peter G. and Williams, Craig M. (2019). New casbanes and the first trans‐cyclopropane seco‐casbane from the Australian rainforest plant croton insularis. Chemistry - A European Journal, 25 (6), 1525-1534. doi: 10.1002/chem.201804904

Synthesis of the seco-limonoid BCD ring system identifies a Hsp90 chaperon machinery (p23) inhibitor

Pinkerton, David M., Chow, Sharon, Eisa, Nada H., Kainth, Kashish, Vanden Berg, Timothy J., Burns, Jed M., Guddat, Luke W., Savage, G. Paul, Chadli, Ahmed and Williams, Craig M. (2019). Synthesis of the seco-limonoid BCD ring system identifies a Hsp90 chaperon machinery (p23) inhibitor. Chemistry - A European Journal, 25 (6), 1451-1455. doi: 10.1002/chem.201805420

Hydrogen-bonding interactions in the Ley-Griffith oxidation: practical considerations for the synthetic chemist

Moore, Peter W., Zerk, Timothy J., Burns, Jed M., Bernhardt, Paul V. and Williams, Craig M. (2019). Hydrogen-bonding interactions in the Ley-Griffith oxidation: practical considerations for the synthetic chemist. European Journal of Organic Chemistry, 2019 (2-3), 303-308. doi: 10.1002/ejoc.201800860

A protocol for an iodine-metal exchange reaction on cubane using lithium organozincates

Kato, Yumi, Williams, Craig M., Uchiyama, Masanobu and Matsubara, Seijiro (2019). A protocol for an iodine-metal exchange reaction on cubane using lithium organozincates. Organic Letters, 21 (2), 473-475. doi: 10.1021/acs.orglett.8b03721

Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

McAlpine, James B., Chen, Shao-Nong, Kutateladze, Andrei, MacMillan, John B., Appendino, Giovanni, Barison, Andersson, Beniddir, Mehdi A., Biavatti, Maique W., Bluml, Stefan, Boufridi, Asmaa, Butler, Mark S., Capon, Robert J., Choi, Young H., Coppage, David, Crews, Phillip, Crimmins, Michael T., Csete, Marie, Dewapriya, Pradeep, Egan, Joseph M., Garson, Mary J., Genta-Jouve, Grégory, Gerwick, William H., Gross, Harald, Harper, Mary Kay, Hermanto, Precilia, Hook, James M., Hunter, Luke, Jeannerat, Damien, Ji, Nai-Yun ... Pauli, Guido F. (2019). Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports, 36 (1), 248-249. doi: 10.1039/c8np90041h

Cover Feature: Hydrogen-Bonding Interactions in the Ley-Griffith Oxidation: Practical Considerations for the Synthetic Chemist (Eur. J. Org. Chem. 2-3/2019)

Moore, Peter W., Zerk, Timothy J., Burns, Jed M., Bernhardt, Paul V. and Williams, Craig M. (2018). Cover Feature: Hydrogen-Bonding Interactions in the Ley-Griffith Oxidation: Practical Considerations for the Synthetic Chemist (Eur. J. Org. Chem. 2-3/2019). European Journal of Organic Chemistry, 2019 (2-3), 230-230. doi: 10.1002/ejoc.201801822

Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections

Garcia, Mario D., Chua, Sheena M. H., Low, Yu-Shang, Lee, Yu-Ting, Agnew-Francis, Kylie, Wang, Jian-Guo, Nouwens, Amanda, Lonhienne, Thierry, Williams, Craig M., Fraser, James A. and Guddat, Luke W. (2018). Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections. Proceedings of the National Academy of Sciences of the United States of America, 115 (41), E9649-E9658. doi: 10.1073/pnas.1809422115

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

McAlpine, James B., Chen, Shao-Nong, Kutateladze, Andrei, MacMillan, John B., Appendino, Giovanni, Barison, Andersson, Beniddir, Mehdi A., Biavatti, Maique W., Bluml, Stefan, Boufridi, Asmaa, Butler, Mark S., Capon, Robert J., Choi, Young H., Coppage, David, Crews, Phillip, Crimmins, Michael T., Csete, Marie, Dewapriya, Pradeep, Egan, Joseph M., Garson, Mary J., Genta-Jouve, Grégory, Gerwick, William H., Gross, Harald, Harper, Mary Kay, Hermanto, Precilia, Hook, James M., Hunter, Luke, Jeannerat, Damien, Ji, Nai-Yun ... Pauli, Guido F. (2018). The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports, 36 (1), 35-107. doi: 10.1039/c7np00064b

Corrigendum to: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere (Angewandte Chemie International Edition, (2016), 55, 11, (3580-3585), 10.1002/anie.201510675)

Chalmers, Benjamin A., Xing, Hui, Houston, Sevan, Clark, Charlotte, Ghassabian, Sussan, Kuo, Andy, Cao, Benjamin, Reitsma, Andrea, Murray, Cody-Ellen P., Stok, Jeanette E., Boyle, Glen M., Pierce, Carly J., Littler, Stuart W., Winkler, David A., Bernhardt, Paul V., Pasay, Cielo, De Voss, James J., McCarthy, James, Parsons, Peter G., Walter, Gimme H., Smith, Maree T., Cooper, Helen M., Nilsson, Susan K., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2018). Corrigendum to: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere (Angewandte Chemie International Edition, (2016), 55, 11, (3580-3585), 10.1002/anie.201510675). Angewandte Chemie - International Edition, 57 (28), 8359-8359. doi: 10.1002/anie.201711161

Developing cyclic peptide heteroatom interchange: synthesis and DFT modelling of a HI-ascidiacyclamide isomer

Xie, Sida, Savchenko, Andrei I., Krenske, Elizabeth H., Grange, Rebecca L., Gahan, Lawrence R. and Williams, Craig M. (2018). Developing cyclic peptide heteroatom interchange: synthesis and DFT modelling of a HI-ascidiacyclamide isomer. European Journal of Organic Chemistry, 2018 (25), 3265-3270. doi: 10.1002/ejoc.201800449

Front cover: developing cyclic peptide heteroatom interchange: synthesis and DFT modelling of a HI-ascidiacyclamide isomer (Eur. J. Org. Chem. /2018)

Xie, Sida, Savchenko, Andrei I., Krenske, Elizabeth H., Grange, Rebecca L., Gahan, Lawrence R. and Williams, Craig M. (2018). Front cover: developing cyclic peptide heteroatom interchange: synthesis and DFT modelling of a HI-ascidiacyclamide isomer (Eur. J. Org. Chem. /2018). European Journal of Organic Chemistry, 2018 (25), 3246-3246. doi: 10.1002/ejoc.201800902

Heteroatom-Interchanged Isomers of Lissoclinamide 5: Copper(II) Complexation, Halide Binding, and Biological Activity

Xie, Sida, Savchenko, Andrei I., Kerscher, Marion, Grange, Rebecca L., Krenske, Elizabeth H., Harmer, Jeffrey R., Bauer, Michelle J., Broit, Natasa, Watters, Dianne J., Boyle, Glen M., Bernhardt, Paul V., Parsons, Peter G., Comba, Peter, Gahan, Lawrence R. and Williams, Craig M. (2018). Heteroatom-Interchanged Isomers of Lissoclinamide 5: Copper(II) Complexation, Halide Binding, and Biological Activity. European Journal of Organic Chemistry, 2018 (12), 1465-1476. doi: 10.1002/ejoc.201701659

ATP3 and MTP3: easily prepared stable perruthenate salts for oxidation applications in synthesis

Moore, Peter W., Read, Christopher D. G., Bernhardt, Paul V. and Williams, Craig M. (2018). ATP3 and MTP3: easily prepared stable perruthenate salts for oxidation applications in synthesis. Chemistry: A European Journal, 24 (18), 4556-4561. doi: 10.1002/chem.201800531

High resolution crystal structures of the acetohydroxyacid synthase-pyruvate complex provide new insights into its catalytic mechanism

Lonhienne, Thierry, Garcia, Mario D., Noble, Chris, Harmer, Jeffrey, Fraser, James A., Williams, Craig M. and Guddat, Luke W. (2017). High resolution crystal structures of the acetohydroxyacid synthase-pyruvate complex provide new insights into its catalytic mechanism. Chemistryselect, 2 (36), 11981-11988. doi: 10.1002/slct.201702128

Elucidating the mechanism of the Ley-Griffith (TPAP) alcohol oxidation

Zerk, Timothy J., Moore, Peter W., Harbort, Joshua S., Chow, Sharon, Byrne, Lindsay, Koutsantonis, George A., Harmer, Jeffrey R., Martinez, Manuel, Williams, Craig M. and Bernhardt, Paul V. (2017). Elucidating the mechanism of the Ley-Griffith (TPAP) alcohol oxidation. Chemical Science, 8 (12), 8435-8442. doi: 10.1039/c7sc04260d

Dialkyl carbonate synthesis via in situ generated carbonyl dibromide on porous glass

Vuong, Khuong Q. , Effenberger, Reinhard, Zilberman, Joseph, Smart, Simon, Williams, Craig M. and McFarland, Eric W. (2017). Dialkyl carbonate synthesis via in situ generated carbonyl dibromide on porous glass. ACS Sustainable Chemistry & Engineering, 5 (9), 7492-7495. doi: 10.1021/acssuschemeng.7b01487

7-Step total synthesis of (+)-EBC-329: Photoisomerisation reveals new seco-casbane family member

Vanden Berg, Timothy J., Pinkerton, David M. and Williams, Craig M. (2017). 7-Step total synthesis of (+)-EBC-329: Photoisomerisation reveals new seco-casbane family member. Organic & Biomolecular Chemistry, 15 (34), 7102-7105. doi: 10.1039/c7ob01400g

An improved preparation of phorbol from croton oil

Pagani, Alberto, Gaeta, Simone, Savchenko, Andrei I., Williams, Craig M. and Appendino, Giovanni (2017). An improved preparation of phorbol from croton oil. Beilstein Journal of Organic Chemistry, 13 (1), 1361-1367. doi: 10.3762/bjoc.13.133

Furofuran lignans from the Simpson Desert species Eremophila macdonnellii

Tan, Y. P., Savchenko, A. I., Broit, N., Boyle, G. M., Parsons, P. G. and Williams, C. M. (2017). Furofuran lignans from the Simpson Desert species Eremophila macdonnellii. Fitoterapia, 126, 93-97. doi: 10.1016/j.fitote.2017.06.004

Asymmetric sequential Cu-catalyzed 1,6/1,4-conjugate additions of hard nucleophiles to cyclic dienones: determination of absolute configurations and origins of enantioselectivity

Blons, Charlie, Morin, Marie S. T., Schmid, Thibault E., Vives, Thomas, Colombel-Rouen, Sophie, Basle, Olivier, Reynaldo, Thibault, Covington, Cody L., Halbert, Stephanie, Cuskelly, Sean N., Bernhardt, Paul V., Williams, Craig M., Crassous, Jeanne, Polavarapu, Prasad L., Crevisy, Christophe, Gerard, Helene and Mauduit, Marc (2017). Asymmetric sequential Cu-catalyzed 1,6/1,4-conjugate additions of hard nucleophiles to cyclic dienones: determination of absolute configurations and origins of enantioselectivity. Chemistry-A European Journal, 23 (31), 7515-7525. doi: 10.1002/chem.201606034

Cover Picture: Towards the Total Synthesis of Gedunin: Construction of the Fully Elaborated ABC Ring System (Asian J. Org. Chem. 5/2017)

Pinkerton, David M., Bernhardt, Paul V., Savage, G. Paul and Williams, Craig M. (2017). Cover Picture: Towards the Total Synthesis of Gedunin: Construction of the Fully Elaborated ABC Ring System (Asian J. Org. Chem. 5/2017). Asian Journal of Organic Chemistry, 6 (5), 475-475. doi: 10.1002/ajoc.201700182

Stable isotope dilution assay (SIDA) and HS-SPME-GCMS quantification of key aroma volatiles for fruit and sap of Australian mango cultivars

San, Anh T., Joyce, Daryl C., Hofman, Peter J., Macnish, Andrew J., Webb, Richard I., Matovic, Nicolas J., Williams, Craig M., De Voss, James J., Wong, Siew H. and Smyth, Heather E. (2017). Stable isotope dilution assay (SIDA) and HS-SPME-GCMS quantification of key aroma volatiles for fruit and sap of Australian mango cultivars. Food Chemistry, 221, 613-619. doi: 10.1016/j.foodchem.2016.11.130

Inhibition of Tyrosinase by 4H-Chromene Analogues: Synthesis, Kinetic Studies and Computational Analysis

Brasil, Edikarlos M., Canavieira, Luciana M., Cardoso, Érica T. C., Silva, Edilene O., Lameira, Jeronimo, Nascimento, Jose L. M., Eifler-Lima, Vera L., de Matos Macchi, Barbarella, Sriram, Dharmarajan, Bernhardt, Paul V., Silva, Jose Rogerio Araujo, Williams, Craig M. and Alves, Claudio N. (2017). Inhibition of Tyrosinase by 4H-Chromene Analogues: Synthesis, Kinetic Studies and Computational Analysis. Chemical Biology and Drug Design, 90 (5), 804-810. doi: 10.1111/cbdd.13001

The first plant 5,6-secosteroid from the Australian arid zone species Frankenia foliosa

Tan, Yuen P. , Savchenko, Andrei I. , Broit, Natasa , Boyle, Glen M. , Parsons, Peter G. and Williams, Craig M. (2017). The first plant 5,6-secosteroid from the Australian arid zone species Frankenia foliosa. European Journal of Organic Chemistry, 2017 (11), 1498-1501. doi: 10.1002/ejoc.201700035

Towards the total synthesis of gedunin: construction of the fully elaborated ABC ring system

Pinkerton, David M., Bernhardt, Paul V., Savage, G. Paul and Williams, Craig M. (2017). Towards the total synthesis of gedunin: construction of the fully elaborated ABC ring system. Asian Journal of Organic Chemistry, 6 (5), 583-597. doi: 10.1002/ajoc.201700013

The 2.0 Å X-ray structure for yeast acetohydroxyacid synthase provides new insights into its cofactor and quaternary structure requirements

Lonhienne, Thierry, Garcia, Mario D., Fraser, James A., Williams, Craig M. and Guddat, Luke W. (2017). The 2.0 Å X-ray structure for yeast acetohydroxyacid synthase provides new insights into its cofactor and quaternary structure requirements. PLoS One, 12 (2) e0171443, e0171443.1-e0171443.13. doi: 10.1371/journal.pone.0171443

Gaining synthetic appreciation for the gedunin ABC ring system

Pinkerton, David M., Vanden Berg, Timothy J., Bernhardt, Paul V. and Williams, Craig M. (2017). Gaining synthetic appreciation for the gedunin ABC ring system. Chemistry - A European Journal, 23 (10), 2282-2285. doi: 10.1002/chem.201605751

The first casbane hydroperoxides EBC-304 and EBC-320 from the Australian rainforest

Maslovskaya, Lidiya A., Savchenko, Andrei I., Gordon, Victoria A., Reddell, Paul W., Pierce, Carly J., Parsons, Peter G. and Williams, Craig M. (2017). The first casbane hydroperoxides EBC-304 and EBC-320 from the Australian rainforest. Chemistry: A European Journal, 23 (3), 537-540. doi: 10.1002/chem.201604674

Hydroxyl radicals via collision-induced dissociation of trimethylammonium benzyl alcohols

Moore, Peter W., Hooker, Jordan P., Zavra, Athanasios, Khairallah, George N., Krenske, Elizabeth H., Bernhardt, Paul V., Quach, Gina, Moore, Evan G., O’Hair, Richard A. J. and William, Craig M. (2017). Hydroxyl radicals via collision-induced dissociation of trimethylammonium benzyl alcohols. Australian Journal of Chemistry, 70 (4), 397-406. doi: 10.1071/CH16602

ChemInform abstract: selectivity modulation of the Ley-Griffith TPAP oxidation with N-oxide salts

Moore, Peter W., Jiao, Yanxiao, Mirzayans, Paul M., Sheng, Lexter Ng Qi, Hooker, Jordan P. and Williams, Craig M. (2016). ChemInform abstract: selectivity modulation of the Ley-Griffith TPAP oxidation with N-oxide salts. ChemInform, 47 (41). doi: 10.1002/chin.201641044

Selectivity modulation of the Ley–Griffith TPAP oxidation with N-oxide salts

Moore, Peter W., Jiao, Yanxiao, Mirzayans, Paul M., Sheng, Lexter Ng Qi, Hooker, Jordan P. and Williams, Craig M. (2016). Selectivity modulation of the Ley–Griffith TPAP oxidation with N-oxide salts. European Journal of Organic Chemistry, 2016 (20), 3401-3407. doi: 10.1002/ejoc.201600453

In Vitro Metabolic Stability and in Vivo Biodistribution of 3‑Methyl-4- furoxancarbaldehyde Using PET Imaging in Rats

Pippin, Adam B., Mohd Arshad, Zaira Hidayah, Vol, Ronald J., Nye, Jonathon A., Ghassabian, Sussan, Williams, Craig M., Mancini, Alessandra, Liotta, Dennis C., Smith, Maree T. and Goodman, Mark M. (2016). In Vitro Metabolic Stability and in Vivo Biodistribution of 3‑Methyl-4- furoxancarbaldehyde Using PET Imaging in Rats. ACS Medicinal Chemistry Letters, 7 (6), 563-567. doi: 10.1021/acsmedchemlett.5b00410

Chromatography with silver nitrate: part 2

Mander, Lewis N. and Williams, Craig M. (2016). Chromatography with silver nitrate: part 2. Tetrahedron, 72 (9), 1133-1150. doi: 10.1016/j.tet.2016.01.004

EBC-318 and 339: Bicyclo[10.2.1]alkanes from Croton insularis

Maslovskaya, Lidia A., Savchenko, Andrei I., Gordon, Victoria A., Reddell, Paul W., Pierce, Carly J., Parsons, Peter G. and Williams, Craig M. (2016). EBC-318 and 339: Bicyclo[10.2.1]alkanes from Croton insularis. RSC Advances, 6 (30), 25110-25113. doi: 10.1039/c6ra02599d

Catalysts containing the adamantane scaffold

Agnew-Francis, Kylie A. and Williams, Craig M. (2016). Catalysts containing the adamantane scaffold. Advanced Synthesis and Catalysis, 358 (5), 675-700. doi: 10.1002/adsc.201500949

seco-Casbanes from the Australian rainforest: ECD predictions key for determining remote absolute configuration

Maslovskaya, Lidia A., Savchenko, Andrei I., Gordon, Victoria A., Reddell, Paul W., Pierce, Carly J., Parsons, Peter G. and Williams, Craig M. (2016). seco-Casbanes from the Australian rainforest: ECD predictions key for determining remote absolute configuration. European Journal of Organic Chemistry, 2016 (9), 1673-1677. doi: 10.1002/ejoc.201501605

Commercial herbicides can trigger the oxidative inactivation of acetohydroxyacid synthase

Lonhienne, Thierry, Nouwens, Amanda, Williams, Craig M., Fraser, James A., Lee, Yu-Ting, West, Nicholas P. and Guddat, Luke W. (2016). Commercial herbicides can trigger the oxidative inactivation of acetohydroxyacid synthase. Angewandte Chemie, 128 (13), 4319-4323. doi: 10.1002/ange.201511985

Frontispiece: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere

Chalmers, Benjamin A., Xing, Hui, Houston, Sevan, Clark, Charlotte, Ghassabian, Sussan, Kuo, Andy, Cao, Benjamin, Reitsma, Andrea, Murray, Cody-Ellen P., Stok, Jeanette E., Boyle, Glen M., Pierce, Carly J., Littler, Stuart W., Winkler, David A., Bernhardt, Paul V., Pasay, Cielo, De Voss, James J., McCarthy, James, Parsons, Peter G., Walter, Gimme H., Smith, Maree T., Cooper, Helen M., Nilsson, Susan K., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2016). Frontispiece: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere. Angewandte Chemie International Edition, 55 (11), 8359-8359. doi: 10.1002/anie.201681161

Adamantane: the heavy weight in catalysis

Agnew-Francis, Kylie and Williams, Craig M. (2016). Adamantane: the heavy weight in catalysis. Advanced Synthesis and Catalysis, 358 (5), 673-673. doi: 10.1002/adsc.201501018

Direct observation of an oxepin from a bacterial cytochrome P450-catalyzed oxidation

Stok, Jeanette E., Chow, Sharon, Krenske, Elizabeth H., Farfan Soto, Clementina, Matyas, Csongor, Poirier, Raymond A., Williams, Craig M. and De Voss, James J. (2016). Direct observation of an oxepin from a bacterial cytochrome P450-catalyzed oxidation. Chemistry: A European Journal, 22 (13), 4408-4412. doi: 10.1002/chem.201600246

Validating Eaton's hypothesis: cubane as a benzene bioisostere

Chalmers, Benjamin A., Xing, Hui, Houston, Sevan, Clark, Charlotte, Ghassabian, Sussan, Kuo, Andy, Cao, Benjamin, Reitsma, Andrea, Murray, Cody-Ellen P., Stok, Jeanette E., Boyle, Glen M., Pierce, Carly J., Littler, Stuart W., Winkler, David A., Bernhardt, Paul V., Pasay, Cielo, De Voss, James J., McCarthy, James, Parsons, Peter G., Walter, Gimme H., Smith, Maree T., Cooper, Helen M., Nilsson, Susan K., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2016). Validating Eaton's hypothesis: cubane as a benzene bioisostere. Angewandte Chemie (International Edition), 55 (11), 3580-3585. doi: 10.1002/anie.201510675

ChemInform Abstract: N,N,N′,N′-Tetramethylenediamine Dioxide (TMEDAO2) Facilitates Atom Economical/Open Atmosphere Ley-Griffith (TPAP) Tandem Oxidation-Wittig Reactions

Read, Christopher D. G., Moore, Peter W. and Williams, Craig M. (2016). ChemInform Abstract: N,N,N′,N′-Tetramethylenediamine Dioxide (TMEDAO2) Facilitates Atom Economical/Open Atmosphere Ley-Griffith (TPAP) Tandem Oxidation-Wittig Reactions. ChemInform, 47 (5), no-no. doi: 10.1002/chin.201605041

Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid Synthase

Lonhienne, Thierry, Nouwens, Amanda, Williams, Craig M., Fraser, James A., Lee, Yu-Ting, West, Nicholas P. and Guddat, Luke W. (2016). Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid Synthase. Angewandte Chemie - International Edition, 55 (13), 4247-4251. doi: 10.1002/anie.201511985

N-Oxides rescue Ru(v) in catalytic Griffith-Ley (TPAP) alcohol oxidations

Zerk, Timothy J., Moore, Peter W., Williams, Craig M. and Bernhardt, Paul V. (2016). N-Oxides rescue Ru(v) in catalytic Griffith-Ley (TPAP) alcohol oxidations. Chemical Communications, 52 (67), 10301-10304. doi: 10.1039/C6CC05440D

Rhodium-Catalyzed [4+3] Cycloaddition to Furans: Direct Access to Functionalized Bicyclo[5.3.0]decane Derivatives

Krainz, Tanja, Chow, Sharon, Korica, Natasa, Bernhardt, Paul V., Boyle, Glen M., Parsons, Peter G., Davies, Huw M. L. and Williams, Craig M. (2015). Rhodium-Catalyzed [4+3] Cycloaddition to Furans: Direct Access to Functionalized Bicyclo[5.3.0]decane Derivatives. European Journal of Organic Chemistry, 2016 (1), 41-44. doi: 10.1002/ejoc.201501271

Do anti-Bredt natural products exist? Olefin strain energy as a predictor of isolability

Krenske, Elizabeth H. and Williams, Craig M. (2015). Do anti-Bredt natural products exist? Olefin strain energy as a predictor of isolability. Angewandte Chemie International Edition, 54 (36), 10608-10612. doi: 10.1002/anie.201503822

N,N,N’,N’-Tetramethylenediamine dioxide (TMEDAO2) facilitates atom economical/open atmosphere Ley–Griffith (TPAP) tandem oxidation-Wittig reactions

Read, Christopher D. G., Peter W. Moore and Williams, Craig M. (2015). N,N,N’,N’-Tetramethylenediamine dioxide (TMEDAO2) facilitates atom economical/open atmosphere Ley–Griffith (TPAP) tandem oxidation-Wittig reactions. Green Chemistry, 17 (9), 4537-4540. doi: 10.1039/C5GC01346A

Pharmaceuticals that contain polycyclic hydrocarbon scaffolds

Stockdale, Tegan P. and Williams, Craig M. (2015). Pharmaceuticals that contain polycyclic hydrocarbon scaffolds. Chemical Society Reviews, 44 (21), 7737-7763. doi: 10.1039/C4CS00477A

ChemInform Abstract: NMO·TPB: A Selectivity Variation on the Ley-Griffith TPAP Oxidation

Moore, Peter W., Mirzayans, Paul M. and Williams, Craig M. (2015). ChemInform Abstract: NMO·TPB: A Selectivity Variation on the Ley-Griffith TPAP Oxidation. ChemInform, 46 (29), no-no. doi: 10.1002/chin.201529041

The Furoxan Nitric Oxide Donor, PRG150, Evokes Dose-Dependent Analgesia in a Rat Model of Painful Diabetic Neuropathy (PDN)

Huang, Lillian Y., Tsui, Debbie Y., Williams, Craig M., Wyse, Bruce D. and Smith, Maree T. (2015). The Furoxan Nitric Oxide Donor, PRG150, Evokes Dose-Dependent Analgesia in a Rat Model of Painful Diabetic Neuropathy (PDN). Clinical and Experimental Pharmacology and Physiology, 42 (9), 921-929. doi: 10.1111/1440-1681.12442

NMO TPB: a selectivity variation on the Ley–Griffith TPAP oxidation

Moore, Peter W., Mirzayans, Paul M. and Williams, Craig M. (2015). NMO TPB: a selectivity variation on the Ley–Griffith TPAP oxidation. Chemistry - A European Journal, 21 (9), 3567-3571. doi: 10.1002/chem.201406256

EBC-316, 325-327, and 345: new pimarane diterpenes from Croton insularis found in the Australian rainforest

Maslovskaya, Lidia A., Savchenko, Andrei I., Gordon, Victoria A., Reddell, Paul W., Pierce, Carly J., Parsons, Peter G. and Williams, Craig M. (2015). EBC-316, 325-327, and 345: new pimarane diterpenes from Croton insularis found in the Australian rainforest. Australian Journal of Chemistry, 68 (4), 652-659. doi: 10.1071/CH14550

Natural Products with Anti-Bredt and Bridgehead Double Bonds

Mak, Jeffrey Y. W., Pouwer, Rebecca H. and Williams, Craig M. (2014). Natural Products with Anti-Bredt and Bridgehead Double Bonds. Angewandte Chemie International Edition, 53 (50), 13664-13688. doi: 10.1002/anie.201400932

Unprecedented 1,14-seco-Crotofolanes from Croton insularis: oxidative cleavage of crotofolin C by a putative homo-Baeyer–Villiger rearrangement

Maslovskaya, Lidiya A., Savchenko, Andrei I., Pierce, Carly J., Gordon, Victoria A., Reddell, Paul W., Parsons, Peter G. and Williams, Craig M. (2014). Unprecedented 1,14-seco-Crotofolanes from Croton insularis: oxidative cleavage of crotofolin C by a putative homo-Baeyer–Villiger rearrangement. Chemistry: A European Journal, 20 (44), 14226-14230. doi: 10.1002/chem.201404250

Croton insularis introduces the seco-casbane class with EBC-329 and the first casbane endoperoxide EBC-324

Maslovskaya, Lidiya A., Savchenko, Andrei I., Krenske, Elizabeth H., Gordon, Victoria A., Reddell, Paul W., Pierce, Carly J., Parsons, Peter G. and Williams, Craig M. (2014). Croton insularis introduces the seco-casbane class with EBC-329 and the first casbane endoperoxide EBC-324. Chemical Communications, 50 (82), 12315-12317. doi: 10.1039/C4CC05413J

EBC-219: A new diterpene skeleton, crotinsulidane, from the Australian rainforest containing a bridgehead double bond

Maslovskaya, Lidiya A., Savchenko, Andrei I., Krenske, Elizabeth H., Pierce, Carly J., Gordon, Victoria A., Reddell, Paul W., Parsons, Peter G. and Williams, Craig M. (2014). EBC-219: A new diterpene skeleton, crotinsulidane, from the Australian rainforest containing a bridgehead double bond. Angewandte Chemie - International Edition, 53 (27), 7006-7009. doi: 10.1002/anie.201310923

Mechanistic aspects of the lycopodine Michael-Claisen domino cyclization

Eger, Wilhelm A., Anders, Ernst and Williams, Craig M. (2014). Mechanistic aspects of the lycopodine Michael-Claisen domino cyclization. Journal of Molecular Modeling, 20 (Online First) (4) 2173, 2173.1-2173.8. doi: 10.1007/s00894-014-2173-0

6th Heron Island conference on reactive intermediates and unusual molecules

Wentrup, Curt and Williams, Craig (2014). 6th Heron Island conference on reactive intermediates and unusual molecules. Australian Journal of Chemistry, 67 (3), 317-319. doi: 10.1071/CH14041

Nonstabilised azomethine ylids from n-oxides: unravelling the deprotonation of n-methylmorpholine n-oxide

Mirzayans, Paul Malek, Krenske, Elizabeth H. and Williams, Craig M. (2014). Nonstabilised azomethine ylids from n-oxides: unravelling the deprotonation of n-methylmorpholine n-oxide. Australian Journal of Chemistry, 67 (8-9), 1309-1317. doi: 10.1071/CH14217

The anti-Bredt red flag! Reassignment of neoveratrenone

Savchenko, Andrei I. and Williams, Craig M. (2013). The anti-Bredt red flag! Reassignment of neoveratrenone. European Journal of Organic Chemistry, Early View (32), 7263-7265. doi: 10.1002/ejoc.201301308

sp-sp(3) Coupling reactions of alkynylsilver cations, RC (equivalent to) CAg2+ (R = Me and Ph) with allyliodide

Khairallah, George N., Williams, Craig M., Chow, Sharon and O'Hair, Richard A. J. (2013). sp-sp(3) Coupling reactions of alkynylsilver cations, RC (equivalent to) CAg2+ (R = Me and Ph) with allyliodide. Dalton Transactions, 42 (26), 9462-9467. doi: 10.1039/c2dt32143b

Chloroform as a hydrogen atom donor in Barton reductive decarboxylation reactions

Ho, Junming, Zheng, Jingling, Meana-Pañeda, Rubén, Truhlar, Donald G., Ko, Eun Jung, Savage, G. Paul, Williams, Craig M., Coote, Michelle L. and Tsanaktsidis, John (2013). Chloroform as a hydrogen atom donor in Barton reductive decarboxylation reactions. Journal of Organic Chemistry, 78 (13), 6677-6687. doi: 10.1021/jo400927y

Photochemical synthesis of phenanthridines: exploring fluoro and protected catechol substitution

Linsenmeier, Anna M., Williams, Craig M. and Brase, Stefan (2013). Photochemical synthesis of phenanthridines: exploring fluoro and protected catechol substitution. European Journal of Organic Chemistry, 18 (18), 3847-3856. doi: 10.1002/ejoc.201300218

CH and CC bond activation reactions in silver alkynyl cluster cations, RCCAg2+

Khairallah, George N., Saleeba, Kirsty A., Chow, Sharon, Eger, Wilhelm, Williams, Craig M. and O'Hair, Richard A. J. (2013). CH and CC bond activation reactions in silver alkynyl cluster cations, RCCAg2+. International Journal of Mass Spectrometry, 354-355, 229-234. doi: 10.1016/j.ijms.2013.07.010

Erratum: Enantioselective total synthesis of ()-neovibsanin G and ()-14-epi-neovibsanin G (Chemical Communications (2012) (287-289) DOI: 10.1039/c1cc15995j))

Mak, Jeffrey Y. W. and Williams, Craig M. (2012). Erratum: Enantioselective total synthesis of ()-neovibsanin G and ()-14-epi-neovibsanin G (Chemical Communications (2012) (287-289) DOI: 10.1039/c1cc15995j)). Chemical Communications, 48 (100) doi: 10.1039/c2cc90426h

A combined DFT and NMR investigation of the zinc organometallic intermediate proposed in the syn-selective tandem chain extension-aldol reaction of β-keto esters

Aiken, Karelle S., Eger, Wilhelm A., Williams, Craig M., Spencer, Carley M. and Zercher, Charles K. (2012). A combined DFT and NMR investigation of the zinc organometallic intermediate proposed in the syn-selective tandem chain extension-aldol reaction of β-keto esters. Journal of Organic Chemistry, 77 (14), 5942-5955. doi: 10.1021/jo3004925

Method in the madness - Methodology from total synthesis

Pouwer, Rebecca H. and Williams, Craig M. (2012). Method in the madness - Methodology from total synthesis. Synlett, 23 (10) ST-2011-A0782-A, 1446-1458. doi: 10.1055/s-0031-1290967

Reductive Radical Decarboxylation of Aliphatic Carboxylic Acids

Ko, Eun Jung, Williams, Craig M., Savage, G. Paul and Tsanaktsidis, John (2012). Reductive Radical Decarboxylation of Aliphatic Carboxylic Acids. Organic Syntheses, 89, 471-479. doi: 10.15227/orgsyn.089.0471

Key achievements in the total synthesis of vibsane-type diterpenoids

Mak, Jeffrey Y. W. and Williams, Craig M. (2012). Key achievements in the total synthesis of vibsane-type diterpenoids. Natural Product Reports, 29 (4), 440-448. doi: 10.1039/c2np00067a

Total synthesis of (-)-neovibsanin G and (-)-14-epi-neovibsanin G: Towards the synthesis of 15-O-methylneovibsanin F and 14-epi-15-O-methylneovibsanin F

Mak, Jeffrey Y. W. and Williams, Craig M. (2012). Total synthesis of (-)-neovibsanin G and (-)-14-epi-neovibsanin G: Towards the synthesis of 15-O-methylneovibsanin F and 14-epi-15-O-methylneovibsanin F. European Journal of Organic Chemistry, 2012 (10), 2001-2012. doi: 10.1002/ejoc.201101796

Stereocontrolled Synthesis of the cis-Hydroxydecalin System: Towards Biologically Active 19-nor-Clerodanes

Mirzayans, Paul Malek, Pouwer, Rebecca H., Williams, Craig M. and Bernhardt, Paul V. (2012). Stereocontrolled Synthesis of the cis-Hydroxydecalin System: Towards Biologically Active 19-nor-Clerodanes. European Journal of Organic Chemistry, 8 (8), 1633-1638. doi: 10.1002/ejoc.201101807

2nd international collaborative and cooperative chemistry symposium

Williams, Craig (2012). 2nd international collaborative and cooperative chemistry symposium. Australian Journal of Chemistry, 65 (9), 1260-1261. doi: 10.1071/CH12231

Enantioselective total synthesis of (-)-neovibsanin G and (-)-14-epi-neovibsanin G

Mak, Jeffrey Y.W. and Williams, Craig M. (2012). Enantioselective total synthesis of (-)-neovibsanin G and (-)-14-epi-neovibsanin G. Chemical Communications, 48 (2), 287-289. doi: 10.1039/c1cc15995j

Enantioselective total synthesis of the mexicanolides: khayasin, proceranolide, and mexicanolide

Faber, Jonathan M., Eger, Wilhelm A. and Williams, Craig M. (2012). Enantioselective total synthesis of the mexicanolides: khayasin, proceranolide, and mexicanolide. Journal of Organic Chemistry, 77 (20), 8913-8921. doi: 10.1021/jo301182f

Synthesis of phenanthridine derivatives via photolysis

Linsenmeier, Anna M., Williams, Craig M. and Brase, Stefan (2011). Synthesis of phenanthridine derivatives via photolysis. Journal of Organic Chemistry, 76 (21), 9127-9132. doi: 10.1021/jo201542x

Determining a synthetic approach to pierisformaside C

Chow, Sharon, Kress, Christoph, Albaek, Nanna, Jessen, Carsten and Williams, Craig M. (2011). Determining a synthetic approach to pierisformaside C. Organic Letters, 13 (19), 5286-5289. doi: 10.1021/ol202147r

The clerodane ring system: investigating the viability of a direct Diels-Alder approach

Merritt, Andrew T., Pouwer, Rebecca H., Williams, David J., Williams, Craig M. and Ley, Steven V. (2011). The clerodane ring system: investigating the viability of a direct Diels-Alder approach. Organic and Biomolecular Chemistry, 9 (13), 4745-4747. doi: 10.1039/c1ob05422h

Understanding the reactivity of acyl anion equivalents: The epoxide ring opening case

Eger, Wilhelm A., Grange, Rebecca L, Schill, Heiko, Goumont, Régis, Clark, Timothy and Williams, Craig M. (2011). Understanding the reactivity of acyl anion equivalents: The epoxide ring opening case. European Journal of Organic Chemistry, 2011 (13), 2548-2553. doi: 10.1002/ejoc.201001680

Reducing the cost, smell, and toxicity of the Barton reductive decarboxylation: Chloroform as the hydrogen atom source

Ko, Eun Jung, Savage, G. Paul, Williams, Craig M. and Tsanaktsidis, John (2011). Reducing the cost, smell, and toxicity of the Barton reductive decarboxylation: Chloroform as the hydrogen atom source. Organic Letters, 13 (8), 1944-1947. doi: 10.1021/ol200290m

Isolation and confirmation of the proposed cleistanthol biogentic link from Croton insularis

Maslovskaya, LA, Savchenko, AI, Gordon, VA, Reddell, PW, Pierce, CJ, Parsons, PG and Williams, CM (2011). Isolation and confirmation of the proposed cleistanthol biogentic link from Croton insularis. Organic Letters, 13 (5), 1032-1035. doi: 10.1021/ol103083m

1,2,4-triazine vs. 1,3- and 1,4-oxazinones in normal- and inverse-electron-demand hetero-diels-alder reactions: Establishing a status quo by computational analysis

Rooshenas, Parham, Hof, Kira, Schreiner, Peter R. and Williams, Craig M. (2011). 1,2,4-triazine vs. 1,3- and 1,4-oxazinones in normal- and inverse-electron-demand hetero-diels-alder reactions: Establishing a status quo by computational analysis. European Journal of Organic Chemistry, 2011 (5), 983-992. doi: 10.1002/ejoc.201001365

A concise total synthesis of (+/-)-cipadonoid B from synthetic azedaralide

Faber, Jonathan M. and Williams, Craig M. (2011). A concise total synthesis of (+/-)-cipadonoid B from synthetic azedaralide. Chemical Communications, 47 (8), 2258-2260. doi: 10.1039/c0cc04698a

Copper(I)-catalyzed cycloaddition of silver acetylides and azides: Incorporation of volatile acetylenes into the triazole core

Silvestri, Ilaria Proietti, Andemarian, Fikre, Khairallah, George N., Yap, Su Wan, Quach, Tim, Tsegay, Sammi, Williams, Craig M., O'Hair, Richard A. J., Donnelly, Paul S. and Williams, Spencer J. (2011). Copper(I)-catalyzed cycloaddition of silver acetylides and azides: Incorporation of volatile acetylenes into the triazole core. Organic and Biomolecular Chemistry, 9 (17), 6082-6088. doi: 10.1039/c1ob05360d

5th Heron Island conference on reactive intermediates and unusual molecules

Wentrup, C and Williams, C (2010). 5th Heron Island conference on reactive intermediates and unusual molecules. Australian Journal of Chemistry, 63 (12), 1597-1597. doi: 10.1071/CH10389

A mechanistic investigation into the zinc carbenoid-mediated homologation reaction by DFT methods: Is a classical donor-acceptor cyclopropane intermediate involved?

Eger, WA, Zercher, CK and Williams, CM (2010). A mechanistic investigation into the zinc carbenoid-mediated homologation reaction by DFT methods: Is a classical donor-acceptor cyclopropane intermediate involved?. Journal of Organic Chemistry, 75 (21), 7322-7331. doi: 10.1021/jo101590t

[4+2] Cycloaddition reactions between 1,8-disubstituted cyclooctatetraenes and diazo dienophiles: Stereoelectronic effects, anticancer properties and application to the synthesis of 7,8-substituted bicyclo [4.2.0] octa-2,4-dienes

Grange, RL, Gallen, MJ, Schill, H, Johns, JP, Dong, L, Parsons, PG, Reddell, PW, Gordon, VA, Bernhardt, PV and Williams, CM (2010). [4+2] Cycloaddition reactions between 1,8-disubstituted cyclooctatetraenes and diazo dienophiles: Stereoelectronic effects, anticancer properties and application to the synthesis of 7,8-substituted bicyclo [4.2.0] octa-2,4-dienes. Chemistry - A European Journal, 16 (29), 8894-8903. doi: 10.1002/chem.200903454

Synthetic neovibsanes and their ability to induce neuronal differentiation in PC12 cells

Chen, Apj, Muller, CC, Cooper, HM and Williams, CM (2010). Synthetic neovibsanes and their ability to induce neuronal differentiation in PC12 cells. Tetrahedron, 66 (34), 6842-6850. doi: 10.1016/j.tet.2010.06.056

Neighboring group stabilization by sigma-holes

O'Hair, Richard A. J., Williams, Craig M. and Clark, Timothy (2010). Neighboring group stabilization by sigma-holes. Journal of Molecular Modeling, 16 (3), 559-565. doi: 10.1007/s00894-009-0567-1

A convenient new route to enantiopure 3-hydroxy-5-oxo esters and 5,6-dihydropyran-2-ones: intricacies of the trithioorthoester protecting group

Grange, Rebecca L. and Williams, Craig M. (2010). A convenient new route to enantiopure 3-hydroxy-5-oxo esters and 5,6-dihydropyran-2-ones: intricacies of the trithioorthoester protecting group. Tetrahedron Letters, 51 (8), 1158-1160. doi: 10.1016/j.tetlet.2009.12.058

Cubane: A new NMR Internal Standard

Chalmers, Benjamin A., Chen, Annette P.-J., Savage, G. Paul and Williams, Craig M. (2010). Cubane: A new NMR Internal Standard. Australian Journal Of Chemistry, 63 (7), 1108-1110. doi: 10.1071/CH10107

Total synthesis of (+) vibsanin E

Schwartz, Brett D., Denton, Justin R., Davies, Huw M. L. and Williams, Craig M. (2009). Total synthesis of (+) vibsanin E. Australian Journal of Chemistry, 62 (9), 980-982. doi: 10.1071/CH09267

Anticancer agents from the Australian tropical rainforest: Spiroacetals EBC-23, 24, 25, 72, 73, 75 and 76

Dong, Lin, Schill, Heiko, Grange, Rebecca L., Porzelle, Achim, Johns, Jenny P., Parsons, Peter G., Gordon, Victoria A., Reddell, Paul W. and Williams, Craig M. (2009). Anticancer agents from the Australian tropical rainforest: Spiroacetals EBC-23, 24, 25, 72, 73, 75 and 76. Chemistry: A European Journal, 15 (42), 11307-11318. doi: 10.1002/chem.200901525

Towards the total synthesis of 3-hydroxyvibsanin E

Schwartz, Brett D., Denton, Justin R., Bernhardt, Paul V., Davies, Huw M. L. and Williams, Craig M. (2009). Towards the total synthesis of 3-hydroxyvibsanin E. Synthesis, 2009 (17), 2840-2846. doi: 10.1055/s-0029-1216912

Total synthesis of (+/-)-4,5-Bis-epi-neovibsanin A and B: A neurite outgrowth comparison study

Chen, Annette P. -J., Müller, C. Catharina, Cooper, Helen M. and Williams, Craig M. (2009). Total synthesis of (+/-)-4,5-Bis-epi-neovibsanin A and B: A neurite outgrowth comparison study. Organic Letters, 11 (16), 3758-3761. doi: 10.1021/ol901406j

Synthesis of cis-vinyltrimethylstannanes and cis-vinylpinacolboronates in a two-step highly regio and stereoselective process

Mirzayans, Paul Malek, Pouwer, Rebecca H., Williams, Craig M. and Bernhardt, Paul V. (2009). Synthesis of cis-vinyltrimethylstannanes and cis-vinylpinacolboronates in a two-step highly regio and stereoselective process. Tetrahedron, 65 (39), 8297-8305. doi: 10.1016/j.tet.2009.06.092

Asymmetric [4+3] cycloadditions between vinylcarbenoids and dienes: Application to the total synthesis of the natural product (-)-5-epi-Vibsanin E

Schwartz, Brett D., Denton, Justin R., Lian, Yajing, Davies, Huw M. L. and Williams, Craig M. (2009). Asymmetric [4+3] cycloadditions between vinylcarbenoids and dienes: Application to the total synthesis of the natural product (-)-5-epi-Vibsanin E. Journal of the American Chemical Society, 131 (23), 8329-8332. doi: 10.1021/ja9019484

Cyclic enones as substrates in the Morita-Baylis-Hillman reaction: Surfactant interactions, scope and scalability with an emphasis on formaldehyde

Schwartz, B.D., Porzelle, A., Jack, K.S., Faber, J. M., Gentle, I.R. and Williams, C. M. (2009). Cyclic enones as substrates in the Morita-Baylis-Hillman reaction: Surfactant interactions, scope and scalability with an emphasis on formaldehyde. Advanced Synthesis & Catalysis, 351 (7-8), 1148-1154. doi: 10.1002/adsc.200800739

Competition between cluster fragmentation, C-C bond coupling and C-X bond activation in silver hexynyl cluster cations, [(C4H9CCAg)(n)Ag](+). Size does matter!

Wang, Farrah Qiuyun, Khairallah, George N., Koutsantonis, George A., Williams, Craig M., Callahan, Damien L. and O'Hair, Richard A. J. (2009). Competition between cluster fragmentation, C-C bond coupling and C-X bond activation in silver hexynyl cluster cations, [(C4H9CCAg)(n)Ag](+). Size does matter!. Physical Chemistry Chemical Physics, 11 (21), 4132-4135. doi: 10.1039/b904687a

University of Queensland-National University of Singapore Joint Symposium

Williams, Craig (2009). University of Queensland-National University of Singapore Joint Symposium. Australian Journal of Chemistry, 62 (62), 949-950. doi: 10.1071/CH09389

Total Synthesis of (+)-2-O-Methylneovibsanin H

Chen, A.P. and Williams, C.M. (2008). Total Synthesis of (+)-2-O-Methylneovibsanin H. Organic Letters, 10 (16), 3441-3443. doi: 10.1021/ol801117e

Structure and absolute stereochemistry of the anticancer agent EBC-23 from the Australian rainforest

Dong, Lin, Gordon, Victoria A., Grange, Rebecca L., Johns, Jenny, Parsons, Peter G., Porzelle, Achim, Reddell, Paul, Schill, Heiko and Williams, Craig M. (2008). Structure and absolute stereochemistry of the anticancer agent EBC-23 from the Australian rainforest. Journal of American Chemical Society, 130 (46), 15262-15263. doi: 10.1021/ja807133p

End game strategies towards the total synthesis of vibsanin E, 3-hydroxyvibsanin E, furanovibsanin A, and 3-O-methylfuranovibsanin A

Schwartz, Brett D., Williams, Craig M. and Bernhardt, Paul V. (2008). End game strategies towards the total synthesis of vibsanin E, 3-hydroxyvibsanin E, furanovibsanin A, and 3-O-methylfuranovibsanin A. Beilstein Journal of Organic Chemistry, 4 (1) 34, 1-9. doi: 10.3762/bjoc.4.34

A general procedure to access methylene ether isonitrile derivatives

Grange, Rebecca L., Williams, Craig M., Dong, Lin and Gordon, Victoria A. (2008). A general procedure to access methylene ether isonitrile derivatives. Synthesis, 2008 (20), 3326-3330. doi: 10.1055/s-0028-1083143

Two-Step Regio- and Stereoselective Synthesis of cis-Vinylstannanes

Malek Mirzayans, P., Pouwer, R. and Williams, C.M. (2008). Two-Step Regio- and Stereoselective Synthesis of cis-Vinylstannanes. Organic Letters, 10 (17), 3861-3863. doi: 10.1021/ol801251m

Towards the total synthesis of Spirovibsanin A: Total synthesis of (±)-5,14-Bis-epi-spirovibsanin A

Gallen, Michael J. and Williams, Craig M. (2008). Towards the total synthesis of Spirovibsanin A: Total synthesis of (±)-5,14-Bis-epi-spirovibsanin A. European Journal of Organic Chemistry, 2008 (27), 4697-4705. doi: 10.1002/ejoc.200800574

Exploiting the Anders-Gassner variant on the Wittig reaction: new methodology for the synthesis of 3,3-dimethylacroyl enol esters

Schwartz, Brett D., Williams, Craig M., Anders, Ernst and Bernhardt, Paul V. (2008). Exploiting the Anders-Gassner variant on the Wittig reaction: new methodology for the synthesis of 3,3-dimethylacroyl enol esters. Tetrahedron, 64 (27), 6482-6487. doi: 10.1016/j.tet.2008.04.068

Experimental determination of the gas phase proton affinities of the conjugate base anions of 2-iodoxybenzoic acid (IBX) and 2-iodosobenzoic acid (IBA)

Waters, Tom, Boulton, Jack, Clark, Timothy, Gallen, Michael J., Williams, Craig M. and O'Hair, Richard A. J. (2008). Experimental determination of the gas phase proton affinities of the conjugate base anions of 2-iodoxybenzoic acid (IBX) and 2-iodosobenzoic acid (IBA). Organic & Biomolecular Chemistry, 6 (6), 2530-2533. doi: 10.1039/b803452d

Total synthesis of (+)-5, 14-bis-epi-Spirovibsanin A

Gallen, M. and Williams, C.M. (2008). Total synthesis of (+)-5, 14-bis-epi-Spirovibsanin A. Organic Letters, 10 (5), 713-715. doi: 10.1021/ol702827x

Investigating direct access to 2-oxospiro[4.5]decanones via 6 pi-electrocyclisation

Pouwer, Rebecca H., Schill, Heiko, Williams, Craig M. and Bernhardt, Paul V. (2007). Investigating direct access to 2-oxospiro[4.5]decanones via 6 pi-electrocyclisation. European Journal of Organic Chemistry, 2007 (28), 4699-4705. doi: 10.1002/ejoc.200700367

Rapid access to in situ generated (R)- and (S)-2-furyloxirane and associated regioselective nucleophilic ring-opening studies

Porzelle, A, Gordon, VA and Williams, CM (2007). Rapid access to in situ generated (R)- and (S)-2-furyloxirane and associated regioselective nucleophilic ring-opening studies. Synlett, 2007 (10), 1619-1621. doi: 10.1055/s-2007-980381

Investigating direct alkynylation at the bridgehead of bicyclic cages using silver(I) acetylides

Pouwer, R. H., Harper, J. B., Vyakaranam, K., Michl, J., Williams, C. M., Jessen, C. H. and Bernhardt, P. V. (2007). Investigating direct alkynylation at the bridgehead of bicyclic cages using silver(I) acetylides. European Journal of Organic Chemistry, 2007 (2), 241-248. doi: 10.1002/ejoc.200600701

Azedaralide: total synthesis, relative and absolute stereochemical assignment

Baker, L. A., Williams, C. M., Bernhardt, P. V. and Yanik, G. W. (2006). Azedaralide: total synthesis, relative and absolute stereochemical assignment. Tetrahedron, 62 (31), 7355-7360. doi: 10.1016/j.tet.2006.05.030

Direct access to functionalized cyclic enones using Mannich, Morita-Baylis-Hillman and elimination reactions

Porzelle, Achim and Williams, Craig M. (2006). Direct access to functionalized cyclic enones using Mannich, Morita-Baylis-Hillman and elimination reactions. Synthesis, 18 (18), 3025-3030. doi: 10.1055/s-2006-942539

Towards the total synthesis of vibsanin E, 15-O-methylcyclovibsanin B, 3-hydroxyvibsanin E, furanovibsanin A, and 3-O-methylfuranovibsanin A

Schwartz, B. D., Tilly, D. P., Heim, R., Wiedemann, S., Williams, C. M. and Bernhardt, P. V. (2006). Towards the total synthesis of vibsanin E, 15-O-methylcyclovibsanin B, 3-hydroxyvibsanin E, furanovibsanin A, and 3-O-methylfuranovibsanin A. European Journal of Organic Chemistry, 2006 (14), 3181-3192. doi: 10.1002/ejoc.200600246

o-iodoxybenzoic acid (IBX): pK(a) and proton-affinity analysis

Gallen, Michael J., Goummont, Regis, Clark, Timothy, Terrier, Francois and Williams, Craig M. (2006). o-iodoxybenzoic acid (IBX): pK(a) and proton-affinity analysis. Angewandte Chemie-international Edition, 45 (18), 2929-2934. doi: 10.1002/anie.200504156

"One-Step" alkynylation of adamantyl iodide with Silver(I) acetylides

Pouwer, R. H., Williams, C. M., Raine, A. L. and Harper, J. B. (2005). "One-Step" alkynylation of adamantyl iodide with Silver(I) acetylides. Organic Letters, 7 (7), 1323-1325. doi: 10.1021/ol050121+

Construction of the cyclovibsanin core via a biogenetically modeled approach

Tilly, David P., Williams, Craig M. and Bernhardt, Paul V. (2005). Construction of the cyclovibsanin core via a biogenetically modeled approach. Organic Letters, 7 (23), 5155-5157. doi: 10.1021/ol051897d

Evaluating the Baylis-Hillman reaction of cyclic enones using surfactants in water

Porzelle, A., Williams, C. M., Schwartz, B. D. and Gentle, I. R. (2005). Evaluating the Baylis-Hillman reaction of cyclic enones using surfactants in water. Synlett, 19 (19) D25505ST, 2923-2926. doi: 10.1055/s-2005-921890

Expedient construction of the vibsanin E core without the use of protecting groups

Heim, Ralf, Wiedemann, Stefan, Williams, Craig M. and Bernhardt, Paul V. (2005). Expedient construction of the vibsanin E core without the use of protecting groups. Organic Letters, 7 (7), 1327-1329. doi: 10.1021/ol0501222

Investigating direct routes to an advanced intermediate for the synthesis of C-20 diterpene alkaloids

Williams, C. M., Mander, L. N., Bernhardt, P. V. and Willis, A. C. (2005). Investigating direct routes to an advanced intermediate for the synthesis of C-20 diterpene alkaloids. Tetrahedron, 61 (15), 3759-3769. doi: 10.1016/j.tet.2005.02.014

Nitrogen is a requirement for the photochemical induced 3-azabicyclo[3.3.1]nonane skeletal rearrangement!

Williams, C. M., Heim, R. and Bernhardt, P. V. (2005). Nitrogen is a requirement for the photochemical induced 3-azabicyclo[3.3.1]nonane skeletal rearrangement!. Tetrahedron, 61 (15), 3771-3779. doi: 10.1016/j.tet.2005.02.013

Guaiacol transprotection: replacement of the phenoxy isopropyl protecting function by acetyl

Williams, Craig M. and Mander, Lewis N. (2004). Guaiacol transprotection: replacement of the phenoxy isopropyl protecting function by acetyl. Tetrahedron Letters, 45 (4), 667-669. doi: 10.1016/j.tetlet.2003.11.065

Unprecedented photochemical induced cascading rearrangement of the 3-azabicyclo[3.3.1] nonane skeleton

Williams, Craig M., Heim, Ralf, Brecknell, Douglas J. and Bernhardt, Paul V. (2004). Unprecedented photochemical induced cascading rearrangement of the 3-azabicyclo[3.3.1] nonane skeleton. Organic and Biomolecular Chemistry, 2 (6), 806-807. doi: 10.1039/b402200a

The synthesis and X-ray crystal structure of 9-carboxyhexahydro-7-methoxy-4a,7-ethano-benzopyran-5-en-1-one

Williams, C. M., Bernhardt, P. V., Wiedemann, S. and Barden, M. C. (2003). The synthesis and X-ray crystal structure of 9-carboxyhexahydro-7-methoxy-4a,7-ethano-benzopyran-5-en-1-one. Journal of Chemical Research (S), 12 (12), 784-785. doi: 10.3184/030823403322840387

1-Ethynyl-2-isopropoxy-3-methoxybenzene

Williams, Craig M., Mander, Lewis N. and Bernhardt, Paul V. (2003). 1-Ethynyl-2-isopropoxy-3-methoxybenzene. Acta Crystallographica Section E, 59 (4), 0561-0563. doi: 10.1107/S1600536803006585

Synthesis of novel 2-amino-1,3-thiazole-5-carboxylates utilising ultrasonic and thermally mediated aminolysis

Baker, L. A. and Williams, C. M. (2003). Synthesis of novel 2-amino-1,3-thiazole-5-carboxylates utilising ultrasonic and thermally mediated aminolysis. Journal of Heterocyclic Chemistry, 40 (2), 353-356. doi: 10.1002/jhet.5570400225

An improved preparation of 4-amino-3-mercaptobenzoic acid

Lang, R. C., Williams, C. M. and Garson, M. J. (2003). An improved preparation of 4-amino-3-mercaptobenzoic acid. Organic Preparations And Procedures International, 35 (3), 520-524. doi: 10.1080/00304940309355864

Bridgehead arylation: A direct route to advanced intermediates for the synthesis of C-20 diterpene alkaloids

Williams, C. M. and Mander, L. N. (2003). Bridgehead arylation: A direct route to advanced intermediates for the synthesis of C-20 diterpene alkaloids. Organic Letters, 5 (19), 3499-3502. doi: 10.1021/ol0353060

Intramolecular titanium-mediated aminocyclopropanation of terminal alkenes: Easy access to various substituted azabicyclo[n.1.0]alkanes

Tebben, G. D., Rauch, K., Stratmann, C., Williams, C. M. and de Meijere, A. (2003). Intramolecular titanium-mediated aminocyclopropanation of terminal alkenes: Easy access to various substituted azabicyclo[n.1.0]alkanes. Organic Letters, 5 (4), 483-485. doi: 10.1021/ol027352q

Oxidative degradation of benzene rings

Mander, L. N. and Williams, C. M. (2003). Oxidative degradation of benzene rings. Tetrahedron, 59 (8), 1105-1136. doi: 10.1016/S0040-4020(02)01492-8

The synthesis and X-ray crystal structure of 6-bromo-2,4,4-trimethyl-cyclohex-2-enone

Williams, C. M. and Bernhardt, P. V. (2003). The synthesis and X-ray crystal structure of 6-bromo-2,4,4-trimethyl-cyclohex-2-enone. Journal of Chemical Research-s, 2003 (7), 410-411. doi: 10.3184/030823403103174326

Mono- and disubstituted Nu,Nu-dialkylcyclopropylamines from dialkylformamides via ligand-exchanged titanium-alkene complexes

de Meijere, A, Williams, CM, Kourdioukov, A, Sviridov, SV, Chaplinski, V, Kordes, M, Savchenko, AI, Stratmann, C and Noltemeyer, M (2002). Mono- and disubstituted Nu,Nu-dialkylcyclopropylamines from dialkylformamides via ligand-exchanged titanium-alkene complexes. Chemistry: A European Journal, 8 (16), 3789-3801. doi: 10.1002/1521-3765(20020816)8:16<3789::AID-CHEM3789>3.0.CO;2-R

1-(Phenylethynyl)adamantane

Raine, A. L., Williams, C. M. and Bernhardt, P. V. (2002). 1-(Phenylethynyl)adamantane. Acta Crystallographica Section E - Structure Reports, E58 (12), 1439-1440. doi: 10.1107/S1600536802021542

Inhibition of adventitious rooting in Backhousia citriodora F. Muell cuttings correlate with the concentration of essential oil

Kibbler, H., Williams, C. M., Williams, R. R. and Johnston, M. E. (2002). Inhibition of adventitious rooting in Backhousia citriodora F. Muell cuttings correlate with the concentration of essential oil. Journal of Horticultural Science & Biotechnology, 77 (6), 705-711. doi: 10.1080/14620316.2002.11511560

Chromatography with silver nitrate

Williams, C. M. and Mander, L. N. (2001). Chromatography with silver nitrate. Tetrahedron, 57 (3), 425-447. doi: 10.1016/S0040-4020(00)00927-3

An unprecedented stereoselective titanium-mediated dihydrodimerization of allyl ethers and allylamines

de Meijere, A, Stecker, B, Kourdioukov, A and Williams, CM (2000). An unprecedented stereoselective titanium-mediated dihydrodimerization of allyl ethers and allylamines. Synthesis-Stuttgart (7), 929-934. doi: 10.1055/s-2000-6297

Base-catalysed rearrangements of 5-oxodihydroisoxazoles

Prager, RH and Williams, CM (1999). Base-catalysed rearrangements of 5-oxodihydroisoxazoles. Heterocycles, 51 (12), 3013-3030.

The synthesis of almazoles A and B

Khalafy, J, Prager, RH and Williams, CM (1999). The synthesis of almazoles A and B. Australian Journal of Chemistry, 52 (1), 31-36. doi: 10.1071/C98093

Easy access to various substituted 4-aminocyclopentenes by rearrangement of 2-ethenyl-substituted cyclopropylamines

Williams, CM and de Meijere, A (1998). Easy access to various substituted 4-aminocyclopentenes by rearrangement of 2-ethenyl-substituted cyclopropylamines. Journal of the Chemical Society-Perkin Transactions 1 (22), 3699-3702. doi: 10.1039/a807012a

Unexpected titanium shifts during cyclopropanation of N,N-dibenzylformamide with ligand-exchanged titanium-alkadiene complexes

Williams, CM, Chaplinski, V, Schreiner, PR and de Meijere, A (1998). Unexpected titanium shifts during cyclopropanation of N,N-dibenzylformamide with ligand-exchanged titanium-alkadiene complexes. Tetrahedron Letters, 39 (42), 7695-7698. doi: 10.1016/S0040-4039(98)01665-7

A new synthesis of chiral aminoalkyloxazolecarboxylate esters from isoxazol-5(2H)-ones: the synthesis of almazoles A and B

Khalafy, J, Svensson, CE, Prager, RH and Williams, CM (1998). A new synthesis of chiral aminoalkyloxazolecarboxylate esters from isoxazol-5(2H)-ones: the synthesis of almazoles A and B. Tetrahedron Letters, 39 (30), 5405-5408. doi: 10.1016/S0040-4039(98)01014-4

Chemistry of 5-oxodihydroisoxazoles .17. Acylation of 5-oxodihydroisoxazoles

Prager, RH, Smith, JA, Weber, B and Williams, CM (1997). Chemistry of 5-oxodihydroisoxazoles .17. Acylation of 5-oxodihydroisoxazoles. Journal of The Chemical Society-perkin Transactions 1 (17), 2659-2664. doi: 10.1039/a700133i

Chemistry of 5-oxodihydroisoxazoles .18. Synthesis of oxazoles by the photolysis and pyrolysis of 2-acyl-5-oxo-2,5-dihydroisoxazoles

Prager, RH, Smith, JA, Weber, B and Williams, CM (1997). Chemistry of 5-oxodihydroisoxazoles .18. Synthesis of oxazoles by the photolysis and pyrolysis of 2-acyl-5-oxo-2,5-dihydroisoxazoles. Journal of The Chemical Society-perkin Transactions 1 (17), 2665-2672. doi: 10.1039/a700134g

The chemistry of 5-oxodihydroisoxazoles .19. The synthesis and photolysis of N-thioacylisoxazol-5(2H)-ones

Prager, RH, Taylor, MR and Williams, CM (1997). The chemistry of 5-oxodihydroisoxazoles .19. The synthesis and photolysis of N-thioacylisoxazol-5(2H)-ones. Journal of The Chemical Society-perkin Transactions 1 (17), 2673-2678. doi: 10.1039/a700646b

The synthesis of oxazoles by thermolysis or photolysis of 2-acylisoxazol-5-ones

Ang K.H., Prager R.H., Smith J.A., Weber B. and Williams C.M. (1996). The synthesis of oxazoles by thermolysis or photolysis of 2-acylisoxazol-5-ones. Tetrahedron Letters, 37 (5), 675-678. doi: 10.1016/0040-4039(95)02240-6

The chemistry of 5-oxodihydroisoxazoles .16. A new synthesis of pyrroles, furans, thiophens and their benzo analogues

Prager, RH and Williams, CM (1996). The chemistry of 5-oxodihydroisoxazoles .16. A new synthesis of pyrroles, furans, thiophens and their benzo analogues. Australian Journal of Chemistry, 49 (12), 1315-1323. doi: 10.1071/CH9961315

The Chemistry of 5-Oxodihydroisoxazoles .12. Trapping of Derived Ketenimines with Lithium Amides and Alkyllithiums

Ang, KH, Prager, RH and Williams, CM (1995). The Chemistry of 5-Oxodihydroisoxazoles .12. Trapping of Derived Ketenimines with Lithium Amides and Alkyllithiums. Australian Journal of Chemistry, 48 (1), 55-63. doi: 10.1071/CH9950055

The Chemistry of 5-Oxodihydroisoxazoles .13. Reactions of the Imino Carbene Derived From Photolysis of Ethyl 5-Oxo-2-Phenyl-2,5-Dihydroisoxazole-4-Carboxylate

Ang, KH, Prager, RH and Williams, CM (1995). The Chemistry of 5-Oxodihydroisoxazoles .13. Reactions of the Imino Carbene Derived From Photolysis of Ethyl 5-Oxo-2-Phenyl-2,5-Dihydroisoxazole-4-Carboxylate. Australian Journal of Chemistry, 48 (3), 567-575. doi: 10.1071/CH9950567

Chemistry, mode of action and clinical efficacy of the anticancer diterpenoid tigilanol tigliate (EBC-46)

Appendino, G., Pagani, A., Williams, C., Cullen, J., Boyle, G., Parsons, P., Campbell, J., Gordon,, Schmidt, P. and Reddell, P. (2019). Chemistry, mode of action and clinical efficacy of the anticancer diterpenoid tigilanol tigliate (EBC-46). 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), Innsbruck, Austria, 1-5 September, 2019. Stuttgart, Germany: Georg Thieme Verlag. doi: 10.1055/s-0039-3399676

Mass spectrometric analysis of volatile organic compounds produced by duodenal microbiota

Bahr, Constance, Moore, Peter, Shanahan, Erin R., Burn, Paul, Williams, Craig, Holtmann, Gerald J., deVoss, James and Morrison, Mark (2018). Mass spectrometric analysis of volatile organic compounds produced by duodenal microbiota. Annual Meeting of the American Society for Gastrointestinal Endoscopy / Digestive Disease Week, Washington, DC, United States, 2-5 June, 2018. Philadelphia, PA, United States: Elsevier. doi: 10.1016/s0016-5085(18)32307-2

7th Heron Island conference on reactive intermediates and unusual molecules

Wentrup, Curt and Williams, Craig M. (2017). 7th Heron Island conference on reactive intermediates and unusual molecules. Clayton, VIC, Australia: CSIRO. doi: 10.1071/CH17065

Cell culture-based assays identify edible rainforest fruits with potential for chemoprevention of cancer

Aoude, L., Ferguson, B., Gordon, V., Johns, J., Maslovskaya, L., Parsons, P., Pierce, C., Reddell, P., Savchenko, A. and Williams, C. (2008). Cell culture-based assays identify edible rainforest fruits with potential for chemoprevention of cancer. 4th Australian Health and Medical Research Congress, Brisbane, Australia, 16-21 November 2008. Sydney, Australia: AHMRC.

Genomic resources of seven Australian weed species of national significance

Shah, Sarah, Lonhienne, Thierry, Murray, Cody-Ellen, Chen, Yibi, Dougan, Katherine E., Low, Yu Shang, Williams, Craig M., Schenk, Gerhard, Walter, Gimme H., Guddat, Luke W. and Chan, Cheong Xin (2022). Genomic resources of seven Australian weed species of national significance. The University of Queensland. (Dataset) doi: 10.48610/c22c10c

Olefin strain energy as a predictor of isolability

Krenske, Elizabeth H. and Williams, Craig M. (2016). Olefin strain energy as a predictor of isolability. The University of Queensland. (Dataset) doi: 10.14264/uql.2016.208

Methods of treating pain

Smith, Maree and Williams, Craig (2006). Methods of treating pain. PCT/AU2005/001976.

Compositions comprising nitric oxide donors and opioid analgesics

Smith, M. T., Brown, L. C., Harvey, M. and Williams, C. M. (2003). Compositions comprising nitric oxide donors and opioid analgesics. PCT/AU03/00335.