The University of Queensland

Biotechnology approaches to produce potent, self-adjuvanting antigen-adjuvant fusion protein subunit vaccines

Moyle, Peter Michael (2017). Biotechnology approaches to produce potent, self-adjuvanting antigen-adjuvant fusion protein subunit vaccines. Biotechnology Advances, 35 (3), 375-389. doi: 10.1016/j.biotechadv.2017.03.005

Progress in vaccine development

Moyle, Peter Michael (2015). Progress in vaccine development. Current Protocols in Microbiology. (pp. 18.1.1-18.1.26) edited by Richard Coico. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9780471729259.mc1801s36

Site-specific incorporation of three toll-like receptor 2 targeting adjuvants into semisynthetic, molecularly defined nanoparticles: application to group A streptococcal vaccines

Moyle, Peter M., Dai, Wei, Zhang, Yingkai, Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2014). Site-specific incorporation of three toll-like receptor 2 targeting adjuvants into semisynthetic, molecularly defined nanoparticles: application to group A streptococcal vaccines. Bioconjugate Chemistry, 25 (5), 965-978. doi: 10.1021/bc500108b

An efficient, chemically-defined semisynthetic lipid-adjuvanted nanoparticulate vaccine development system

Moyle, Peter M., Hartas, Jon, Henningham, Anna, Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2013). An efficient, chemically-defined semisynthetic lipid-adjuvanted nanoparticulate vaccine development system. Nanomedicine: Nanotechnology, Biology and Medicine, 9 (7), 935-944. doi: 10.1016/j.nano.2013.01.009

Modern subunit vaccines: development, components, and research opportunities

Moyle, Peter Michael and Toth, Istvan (2013). Modern subunit vaccines: development, components, and research opportunities. ChemMedChem, 8 (3), 360-376. doi: 10.1002/cmdc.201200487

Method for the synthesis of mono-ADP-ribose conjugated peptides

Moyle, Peter M. and Muir, Tom W (2010). Method for the synthesis of mono-ADP-ribose conjugated peptides. Journal of the American Chemical Society, 132 (45), 15878-15880. doi: 10.1021/ja1064312

Progress in vaccine development

Moyle, Peter Michael (2015). Progress in vaccine development. Current Protocols in Microbiology. (pp. 18.1.1-18.1.26) edited by Richard Coico. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9780471729259.mc1801s36

Lipopeptide-based vaccines

Jackson, David C., Chua, Brendon Y., Brown, Lorena E., Moyle, Peter and Toth, Istvan (2010). Lipopeptide-based vaccines. New generation vaccines. (pp. 315-326) edited by Myron M. Levine. New York, U.S.A.; London, U.K.: Informa Healthcare. doi: 10.3109/9781420060744-32

Strategies in oral immunization

Simerska, Pavla, Moyle, Peter M., Olive, Colleen and Toth, Istvan (2009). Strategies in oral immunization. Oral Delivery of Macromolecular Drugs: Barriers, Strategies and Future Trends. (pp. 195-222) edited by Bernkop-Schnurch, Andreas. New York, United States: Springer. doi: 10.1007/978-1-4419-0200-9_11

Efficacy of Alum-Adjuvanted Peptide and Carbohydrate Conjugate Vaccine Candidates against Group A Streptococcus Pharyngeal Infection in a Non-Human Primate Model

Rivera-Hernandez, Tania, Carnathan, Diane G., Richter, Johanna, Marchant, Patrick, Cork, Amanda J., Elangovan, Gayathiri, Henningham, Anna, Cole, Jason N., Choudhury, Biswa, Moyle, Peter M., Toth, Istvan, Batzloff, Michael R., Good, Michael F., Agarwal, Paresh, Kapoor, Neeraj, Nizet, Victor, Silvestri, Guido and Walker, Mark J. (2024). Efficacy of Alum-Adjuvanted Peptide and Carbohydrate Conjugate Vaccine Candidates against Group A Streptococcus Pharyngeal Infection in a Non-Human Primate Model. Vaccines, 12 (4), 382. doi: 10.3390/vaccines12040382

Recent advances in the delivery and applications of nonviral CRISPR/Cas9 gene editing

Sinclair, Frazer, Begum, Anjuman A., Dai, Charles C., Toth, Istvan and Moyle, Peter M. (2023). Recent advances in the delivery and applications of nonviral CRISPR/Cas9 gene editing. Drug Delivery and Translational Research, 13 (5), 1500-1519. doi: 10.1007/s13346-023-01320-z

Sortase A Inhibitor Protein Nanoparticle Formulations Demonstrate Antibacterial Synergy When Combined with Antimicrobial Peptides

Alharthi, Sitah, Popat, Amirali, Ziora, Zyta Maria and Moyle, Peter Michael (2023). Sortase A Inhibitor Protein Nanoparticle Formulations Demonstrate Antibacterial Synergy When Combined with Antimicrobial Peptides. Molecules, 28 (5) 2114, 1-17. doi: 10.3390/molecules28052114

Formulation and biological evaluation of mesoporous silica nanoparticles loaded with combinations of sortase A inhibitors and antimicrobial peptides

Alharthi, Sitah, Ziora, Zyta M., Janjua, Taskeen, Popat, Amirali and Moyle, Peter M. (2022). Formulation and biological evaluation of mesoporous silica nanoparticles loaded with combinations of sortase A inhibitors and antimicrobial peptides. Pharmaceutics, 14 (5) 986, 986. doi: 10.3390/pharmaceutics14050986

Optimized protocols for assessing libraries of poorly soluble sortase A inhibitors for antibacterial activity against medically-relevant bacteria, toxicity and enzyme inhibition

Alharthi, Sitah, Ziora, Zyta Maria and Moyle, Peter Michael (2021). Optimized protocols for assessing libraries of poorly soluble sortase A inhibitors for antibacterial activity against medically-relevant bacteria, toxicity and enzyme inhibition. Bioorganic and Medicinal Chemistry, 52 116527, 116527. doi: 10.1016/j.bmc.2021.116527

Sortase A (SrtA) inhibitors as an alternative treatment for superbug infections

Alharthi, Sitah, Ebrahim Alavi, Seyed, Michael Moyle, Peter and Maria Ziora, Zyta (2021). Sortase A (SrtA) inhibitors as an alternative treatment for superbug infections. Drug Discovery Today, 26 (9), 2164-2172. doi: 10.1016/j.drudis.2021.03.019

YY‐11, a camel milk‐derived peptide, inhibits TGF‐β‐mediated atherogenic signaling in human vascular smooth muscle cells

Hussain, Humaira, Cao, Yingnan, Mohamad, Raafat, Afroz, Rizwana, Zhou, Ying, Moyle, Peter, Bansal, Nidhi, Wattoo, Feroza Hamid, Kamato, Danielle and Little, Peter J. (2021). YY‐11, a camel milk‐derived peptide, inhibits TGF‐β‐mediated atherogenic signaling in human vascular smooth muscle cells. Journal of Food Biochemistry, 46 (3) e13882, e13882. doi: 10.1111/jfbc.13882

Neutralisation of adeno-associated virus transduction by human vitreous humour

Andrzejewski, Sławomir, Moyle, Peter M., Stringer, Brett W., Steel, Jason C. and Layton, Christopher J. (2021). Neutralisation of adeno-associated virus transduction by human vitreous humour. Gene Therapy, 28 (5), 242-255. doi: 10.1038/s41434-020-0162-8

Developing GLP-1 conjugated self-assembling nanofibers using copper-catalyzed alkyne–azide cycloaddition and evaluation of their biological activity

Alavi, Seyed Ebrahim, Cabot, Peter J., Raza, Aun and Moyle, Peter M. (2021). Developing GLP-1 conjugated self-assembling nanofibers using copper-catalyzed alkyne–azide cycloaddition and evaluation of their biological activity. Bioconjugate Chemistry, 32 (4), 810-820. doi: 10.1021/acs.bioconjchem.1c00091

Erratum for: An experimental group a Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model (mBio, (2019) 10, 2, 10.1128/mBio.00693-19)

Rivera-Hernandez, Tania, Carnathan, Diane G., Jones, Scott, Cork, Amanda J., Davies, Mark R., Moyle, Peter M., Toth, Istvan, Batzloff, Michael R., McCarthy, James, Nizet, Victor, Goldblatt, David, Silvestri, Guido and Walker, Mark J. (2020). Erratum for: An experimental group a Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model (mBio, (2019) 10, 2, 10.1128/mBio.00693-19). mBio, 11 (6) e02995-20, 1-1. doi: 10.1128/mBio.02995-20

Optimized methods for the production and bioconjugation of site-specific, alkyne-modified glucagon-like peptide-1 (GLP-1) analogs to azide-modified delivery platforms using copper-catalyzed alkyne–azide cycloaddition

Alavi, Seyed Ebrahim, Cabot, Peter John, Yap, Gee Yi and Moyle, Peter Michael (2020). Optimized methods for the production and bioconjugation of site-specific, alkyne-modified glucagon-like peptide-1 (GLP-1) analogs to azide-modified delivery platforms using copper-catalyzed alkyne–azide cycloaddition. Bioconjugate Chemistry, 31 (7) acs.bioconjchem.0c00291, 1820-1834. doi: 10.1021/acs.bioconjchem.0c00291

Supercritical fluid assembly of albendazole liposomes targeting gastrin-releasing peptide receptor overexpressing tumors

Maqbool, Faheem, Falconer, James R. and Moyle, Peter M. (2020). Supercritical fluid assembly of albendazole liposomes targeting gastrin-releasing peptide receptor overexpressing tumors. Nanomedicine, 15 (13), 1315-1330. doi: 10.2217/nnm-2020-0048

Development of an enzyme-mediated, site-specific method to conjugate toll-like receptor 2 agonists onto protein antigens: toward a broadly protective, four component, group A streptococcal self-adjuvanting lipoprotein–fusion combination vaccine

Xu, Zhenghui, Rivera-Hernandez, Tania and Moyle, Peter Michael (2020). Development of an enzyme-mediated, site-specific method to conjugate toll-like receptor 2 agonists onto protein antigens: toward a broadly protective, four component, group A streptococcal self-adjuvanting lipoprotein–fusion combination vaccine. ACS Infectious Diseases, 6 (7) acsinfecdis.0c00047, 1770-1782. doi: 10.1021/acsinfecdis.0c00047

Semisynthetic, self-adjuvanting vaccine development: efficient, site-specific sortase A-mediated conjugation of Toll-like receptor 2 ligand FSL-1 to recombinant protein antigens under native conditions and application to a model group A streptococcal vaccine

Xu, Zhenghui, Rivera-Hernandez, Tania, Chatterjee, Oishee, Walker, Mark J. and Moyle, Peter M. (2020). Semisynthetic, self-adjuvanting vaccine development: efficient, site-specific sortase A-mediated conjugation of Toll-like receptor 2 ligand FSL-1 to recombinant protein antigens under native conditions and application to a model group A streptococcal vaccine. Journal of Controlled Release, 317, 96-108. doi: 10.1016/j.jconrel.2019.11.018

A self‐adjuvanting vaccine platform: optimization of site‐specific sortase a mediated conjugation of toll‐like receptor 2 ligands onto the carboxyl or amino terminus of recombinant protein antigens

Xu, Zhenghui and Moyle, Peter Michael (2020). A self‐adjuvanting vaccine platform: optimization of site‐specific sortase a mediated conjugation of toll‐like receptor 2 ligands onto the carboxyl or amino terminus of recombinant protein antigens. ChemPlusChem, 85 (1), 227-236. doi: 10.1002/cplu.201900687

Soil bacterial diffusible and volatile organic compounds inhibit Phytophthora capsici and promote plant growth

Syed-Ab-Rahman, Sharifah Farhana, Carvalhais, Lilia C., Chua, Elvis T., Chung, Fong Yi, Moyle, Peter M., Eltanahy, Eladl G. and Schenk, Peer M. (2019). Soil bacterial diffusible and volatile organic compounds inhibit Phytophthora capsici and promote plant growth. Science of the Total Environment, 692, 267-280. doi: 10.1016/j.scitotenv.2019.07.061

Peptide-based targeted polymeric nanoparticles for siRNA delivery

Hussein, Waleed M., Cheong, Yee S., Liu, Chang, Liu, Genan, Begum, Anjuman Ara, Attallah, Maria Adly, Moyle, Peter Michael, Torchilin, Vladimir, Smith, Roger and Toth, Istvan (2019). Peptide-based targeted polymeric nanoparticles for siRNA delivery. Nanotechnology, 30 (41) 415604, 415604. doi: 10.1088/1361-6528/ab313d

Advances in targeted gene delivery

Begum, Anjuman A., Toth, Istvan, Hussein, Waleed M. and Moyle, Peter Michael (2019). Advances in targeted gene delivery. Current Drug Delivery, 16 (7), 588-608. doi: 10.2174/1567201816666190529072914

Gastrin-releasing peptide receptor-targeted hybrid peptide/phospholipid pDNA/siRNA delivery systems

Begum, Anjuman A., Toth, Istvan and Moyle, Peter M. (2019). Gastrin-releasing peptide receptor-targeted hybrid peptide/phospholipid pDNA/siRNA delivery systems. Nanomedicine, 14 (9), 1153-1171. doi: 10.2217/nnm-2018-0380

Glucagon-like peptide-1 receptor agonists and strategies to improve their efficiency

Alavi, Seyed Ebrahim, Cabot, Peter J. and Moyle, Peter M. (2019). Glucagon-like peptide-1 receptor agonists and strategies to improve their efficiency. Molecular Pharmaceutics, 16 (6) acs.molpharmaceut.9b00308, 2278-2295. doi: 10.1021/acs.molpharmaceut.9b00308

Dispersibility of phospholipids and their optimization for the efficient production of liposomes using supercritical fluid technology

Maqbool, Faheem, Moyle, Peter M., Thurecht, Kristofer J. and Falconer, James R. (2019). Dispersibility of phospholipids and their optimization for the efficient production of liposomes using supercritical fluid technology. International Journal of Pharmaceutics, 563, 174-183. doi: 10.1016/j.ijpharm.2019.03.053

An experimental Group A Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model

Rivera-Hernandez, Tania, Carnathan, Diane G., Jones, Scott, Cork, Amanda J., Davies, Mark R., Moyle, Peter M., Toth, Istvan, Batzloff, Michael R., McCarthy, James, Nizet, Victor, Goldblatt, David, Silvestri, Guido and Walker, Mark J. (2019). An experimental Group A Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model. mBio, 10 (2) e00693-19. doi: 10.1128/mBio.00693-19

Preparation of albendazole-loaded liposomes by supercritical carbon dioxide processing

Maqbool, Faheem, Moyle, Peter M., Tan, Madeleine S. A., Thurecht, Kristofer J. and Falconer, James R. (2019). Preparation of albendazole-loaded liposomes by supercritical carbon dioxide processing. Artificial Cells, Nanomedicine, and Biotechnology, 46 (sup3), 1-7. doi: 10.1080/21691401.2018.1536059

Glucagon-like peptide-1 (GLP-1)-based therapeutics: current status and future opportunities beyond type 2 diabetes

Cheang, Jia Ying and Moyle, Peter Michael (2018). Glucagon-like peptide-1 (GLP-1)-based therapeutics: current status and future opportunities beyond type 2 diabetes. ChemMedChem, 13 (7), 662-671. doi: 10.1002/cmdc.201700781

Bombesin/oligoarginine fusion peptides for gastrin releasing peptide receptor (GRPR) targeted gene delivery

Begum, Anjuman Ara, Wan, Yu, Toth, Istvan and Moyle, Peter M. (2018). Bombesin/oligoarginine fusion peptides for gastrin releasing peptide receptor (GRPR) targeted gene delivery. Bioorganic and Medicinal Chemistry, 26 (2), 516-526. doi: 10.1016/j.bmc.2017.12.013

Bioconjugation approaches to produce subunit vaccines composed of protein or peptide antigens and covalently attached toll-like receptor ligands

Xu, Zhenghui and Moyle, Peter Michael (2017). Bioconjugation approaches to produce subunit vaccines composed of protein or peptide antigens and covalently attached toll-like receptor ligands. Bioconjugate Chemistry, 29 (3), 572-586. doi: 10.1021/acs.bioconjchem.7b00478

Multifunctional peptide-lipid nanocomplexes for efficient targeted delivery of DNA and siRNA into breast cancer cells

Wan, Yu, Dai, Wei, Nevagi, Reshma J., Toth, Istvan and Moyle, Peter M. (2017). Multifunctional peptide-lipid nanocomplexes for efficient targeted delivery of DNA and siRNA into breast cancer cells. Acta Biomaterialia, 59, 257-268. doi: 10.1016/j.actbio.2017.06.032

Biotechnology approaches to produce potent, self-adjuvanting antigen-adjuvant fusion protein subunit vaccines

Moyle, Peter Michael (2017). Biotechnology approaches to produce potent, self-adjuvanting antigen-adjuvant fusion protein subunit vaccines. Biotechnology Advances, 35 (3), 375-389. doi: 10.1016/j.biotechadv.2017.03.005

Design and evaluation of a stearylated multicomponent peptide-siRNA nanocomplex for efficient cellular siRNA delivery.

Wan, Yu, Moyle, Peter M., Gn, Pei Z. and Toth, Istvan (2017). Design and evaluation of a stearylated multicomponent peptide-siRNA nanocomplex for efficient cellular siRNA delivery.. Nanomedicine, 12 (4), 281-293. doi: 10.2217/nnm-2016-0354

Investigation of Bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptor

Begum, Anjuman Ara, Moyle, Peter M. and Toth, Istvan (2016). Investigation of Bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptor. Bioorganic and Medicinal Chemistry, 24 (22), 5834-5841. doi: 10.1016/j.bmc.2016.09.039

Peptide-based multicomponent oligonucleotide delivery systems: optimisation of poly-l-lysine dendrons for plasmid DNA delivery

Kamaruzaman, Khairul A., Moyle, Peter M. and Toth, Istvan (2016). Peptide-based multicomponent oligonucleotide delivery systems: optimisation of poly-l-lysine dendrons for plasmid DNA delivery. International Journal of Peptide Research and Therapeutics, 23 (1), 1-16. doi: 10.1007/s10989-016-9545-5

Differing efficacies of lead Group A Streptococcal vaccine candidates and full-length M protein in cutaneous and invasive disease models

Rivera-Hernandez, Tania, Pandey, Manisha, Henningham, Anna, Cole, Jason, Choudhury, Biswa, Cork, Amanda J., Gillen, Christine M., Ghaffar, Khairunnisa Abdul, West, Nicholas P., Silvestri, Guido, Good, Michael F., Moyle, Peter M., Toth, Istvan, Nizet, Victor, Batzloff, Michael R. and Walker, Mark J. (2016). Differing efficacies of lead Group A Streptococcal vaccine candidates and full-length M protein in cutaneous and invasive disease models. mBio, 7 (3) e00618-16, e00618-16.1-e00618-16.9. doi: 10.1128/mBio.00618-16

Nanosized, peptide-based multicomponent DNA delivery systems: optimization of endosome escape activity

Wan, Yu, Moyle, Peter M., Christie, Michelle P. and Toth, Istvan (2016). Nanosized, peptide-based multicomponent DNA delivery systems: optimization of endosome escape activity. Nanomedicine, 11 (8), 907-919. doi: 10.2217/nnm.16.27

Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccines

Hussein, Waleed M., Liu, Tzu-Yu, Maruthayanar, Pirashanthini, Mukaida, Saori, Moyle, Peter M., Wells, James W., Toth, Istvan and Skwarczynski, Mariusz (2016). Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccines. Chemical Science, 7 (3), 2308-2321. doi: 10.1039/C5SC03859F

Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors

Moyle, Peter M., Dai, Wei, Liu, Tzu-Yu, Hussein, Waleed M., Maruthayanar, Pirashanthini, Wells, James W., McMillan, Nigel A. J., Skwarczynski, Mariusz and Toth, Istvan (2015). Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors. Bioorganic and Medicinal Chemistry Letters, 25 (23), 5570-5575. doi: 10.1016/j.bmcl.2015.10.049

Endosome escape strategies for improving the efficacy of oligonucleotide delivery systems

Wan, Yu, Moyle, Peter M and Toth, Istvan (2015). Endosome escape strategies for improving the efficacy of oligonucleotide delivery systems. Current Medicinal Chemistry, 22 (29), 3326-3346. doi: 10.2174/0929867322666150825162941

Peptide based DNA nanocarriers incorporating a cell-penetrating peptide derived from neurturin protein and poly-L-lysine dendrons

Rosli, Nurlina, Christie, Michelle, Moyle, Peter M. and Toth, Istvan (2015). Peptide based DNA nanocarriers incorporating a cell-penetrating peptide derived from neurturin protein and poly-L-lysine dendrons. Bioorganic & Medicinal Chemistry, 23 (10), 2470-2479. doi: 10.1016/j.bmc.2015.03.058

Group A Streptococcal vaccine candidate: contribution of epitope to size, antigen presenting cell interaction and immunogenicity

Zaman, Mehfuz, Chandrudu, Saranya, Giddam, Ashwini K., Reiman, Jennifer, Skwarczynski, Mariusz, McPhun, Virginia, Moyle, Peter M., Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2014). Group A Streptococcal vaccine candidate: contribution of epitope to size, antigen presenting cell interaction and immunogenicity. Nanomedicine, 9 (17), 2613-2624. doi: 10.2217/NNM.14.190

The contribution of non-human primate models to the development of human vaccines

Rivera-Hernandez, Tania, Carnathan, Diane G., Moyle, Peter M., Toth, Istvan, West, Nicholas P., Young, Paul L., Silvestri, Guido and Walker, Mark J. (2014). The contribution of non-human primate models to the development of human vaccines. Discovery Medicine, 18 (101), 313-322.

Site-specific incorporation of three toll-like receptor 2 targeting adjuvants into semisynthetic, molecularly defined nanoparticles: application to group A streptococcal vaccines

Moyle, Peter M., Dai, Wei, Zhang, Yingkai, Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2014). Site-specific incorporation of three toll-like receptor 2 targeting adjuvants into semisynthetic, molecularly defined nanoparticles: application to group A streptococcal vaccines. Bioconjugate Chemistry, 25 (5), 965-978. doi: 10.1021/bc500108b

Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine

Ahmad Fuaad, Abdullah A. H., Jia, Zhongfan, Hartas, Jon, Ziora, Zyta M., Lin, I-Chun, Moyle, Peter M., Batzloff, Michael R., Good, Michael F., Monteiro, Michael J., Skwarczynski, Mariusz and Toth, Istvan (2014). Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine. Nanomedicine, 9 (1), 35-43. doi: 10.2217/NNM.13.7

An efficient, chemically-defined semisynthetic lipid-adjuvanted nanoparticulate vaccine development system

Moyle, Peter M., Hartas, Jon, Henningham, Anna, Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2013). An efficient, chemically-defined semisynthetic lipid-adjuvanted nanoparticulate vaccine development system. Nanomedicine: Nanotechnology, Biology and Medicine, 9 (7), 935-944. doi: 10.1016/j.nano.2013.01.009

Modern subunit vaccines: development, components, and research opportunities

Moyle, Peter Michael and Toth, Istvan (2013). Modern subunit vaccines: development, components, and research opportunities. ChemMedChem, 8 (3), 360-376. doi: 10.1002/cmdc.201200487

Synthesis and characterization of luteinizing hormone-releasing hormone (LHRH)-functionalized mini-dendrimers

Rafiee, Amirreza, Mansfeld, Friederike M., Moyle, Peter M. and Toth, Istvan (2013). Synthesis and characterization of luteinizing hormone-releasing hormone (LHRH)-functionalized mini-dendrimers. International Journal of Chemistry, 3 (1), 51-57. doi: 10.4236/ijoc.2013.31006

Modern lipid-, carbohydrate-, and peptide-based delivery systems for peptide, vaccine, and gene products

Simerska, Pavla, Moyle, Peter M. and Toth, Istvan (2011). Modern lipid-, carbohydrate-, and peptide-based delivery systems for peptide, vaccine, and gene products. Medicinal Research Reviews, 31 (4), 520-547. doi: 10.1002/med.20191

Method for the synthesis of mono-ADP-ribose conjugated peptides

Moyle, Peter M. and Muir, Tom W (2010). Method for the synthesis of mono-ADP-ribose conjugated peptides. Journal of the American Chemical Society, 132 (45), 15878-15880. doi: 10.1021/ja1064312

Oral vaccine delivery - New strategies and technologies

Simerska, Pavla, Moyle, Peter M., Olive, Colleen and Toth, Istvan (2009). Oral vaccine delivery - New strategies and technologies. Current Drug Delivery, 6 (4), 347-358. doi: 10.2174/156720109789000537

Development of a liposaccharide-based delivery system and its application to the design of Group A streptococcal vaccines

Simerska, Pavla, Abdel-Aal, Abu-Baker M., Fujita, Yoshio, Moyle, Peter M., McGeary, Ross P., Batzloff, Michael R., Olive, Colleen, Good, Michael F. and Toth, Istvan (2008). Development of a liposaccharide-based delivery system and its application to the design of Group A streptococcal vaccines. Journal of Medicinal Chemistry, 51 (5), 1447-1452. doi: 10.1021/jm701410p

Structure-activity relationship of a series of synthetic lipopeptide self-adjuvanting group A streptococcal vaccine candidates

Abdel-Aal, Abu-Baker M., Batzloff, Michael R., Fujita, Yoshio, Barozzi, Nadia, Faria, Andres, Simerska, Pavla, Moyle, Peter M., Good, Michael F. and Toth, Istvan (2008). Structure-activity relationship of a series of synthetic lipopeptide self-adjuvanting group A streptococcal vaccine candidates. Journal of Medicinal Chemistry, 51 (1), 167-172. doi: 10.1021/jm701091d

Self-adjuvanting lipopeptide vaccines

Moyle, P.M. and Toth, I. (2008). Self-adjuvanting lipopeptide vaccines. Current Medicinal Chemistry, 15 (5), 506-516. doi: 10.2174/092986708783503249

Towards the Development of a Broadly Protective Group A Streptococcal Vaccine Based on the Lipid-Core Peptide System

Olive, C., Moyle, P. and Toth, I. (2007). Towards the Development of a Broadly Protective Group A Streptococcal Vaccine Based on the Lipid-Core Peptide System. Current Medicinal Chemistry, 14 (28), 2976-2988. doi: 10.2174/092986707782794069

A technique for the synthesis of highly-pure, mono-epitopic, multi-valent lipid core peptide vaccines

Moyle, PM, Hari, Y, Huang, N, Olive, C, Good, MF and Toth, I (2007). A technique for the synthesis of highly-pure, mono-epitopic, multi-valent lipid core peptide vaccines. Tetrahedron Letters, 48 (29), 4965-4967. doi: 10.1016/j.tetlet.2007.05.129

Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines

Moyle, Peter M., Olive, Colleen, Ho, Mei-Fong, Pandey, Manisha, Dyer, Joanne, Suhrbier, Andreas, Fujita, Yoshio and Toth, Istvan (2007). Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines. Journal of Medicinal Chemistry, 50 (19), 4721-4727. doi: 10.1021/jm070287b

Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical Ligation

Moyle, P. M., Olive, C., Ho, M. F., Burgess, M., Karpati, L., Good, M. F. and Toth, I. (2006). Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical Ligation. Journal of Organic Chemistry, 71 (18), 6846-6850. doi: 10.1021/jo060960p

The lipid core peptide system in vaccine delivery

Toth, Istvan, Moyle, Peter, Karpati, Levente, Horvath, Aniko, Olive, Colleen and Good, Michael (2006). The lipid core peptide system in vaccine delivery. International Congress Series, 1289, 307-310. doi: 10.1016/j.ics.2005.11.057

Method for the synthesis of highly pure vaccines using the lipid core peptide system

Moyle, P. M., Olive, C., Good, M. F. and Toth, I. (2006). Method for the synthesis of highly pure vaccines using the lipid core peptide system. Journal of Peptide Science, 12 (12), 800-807. doi: 10.1002/psc.815

Synthesis of a highly pure lipid core peptide based self-adjuvanting triepitopic group A Streptococcal vaccine, and subsequent immunological evaluation

Moyle, P. M., Olive, C., Ho, M. F., Good, M. F. and Toth, I. (2006). Synthesis of a highly pure lipid core peptide based self-adjuvanting triepitopic group A Streptococcal vaccine, and subsequent immunological evaluation. Journal of Medicinal Chemistry, 49 (21), 6364-6370. doi: 10.1021/jm060475m

Towards the synthesis of a highly pure, multiepitopic, mucosal group A streptoccal lipopeptide vaccine

Moyle, P. M., Olive, C., Ho, M.-F., Burgess, M., Karpati, L., Good, M. F. and Toth, I. (2006). Towards the synthesis of a highly pure, multiepitopic, mucosal group A streptoccal lipopeptide vaccine. International Congress Series, 1289, 324-328. doi: 10.1016/j.ics.2005.11.084

Mucosal immunization: Adjuvants and delivery systems

Moyle, P.M., McGeary, R. P., Blanchfield, J. T. and Toth, I. (2004). Mucosal immunization: Adjuvants and delivery systems. Current Drug Delivery, 1 (4), 385-396. doi: 10.2174/1567201043334588

Development of lipid-core-peptide (LCP) based vaccines for the prevention of the group A streptococcal (GAS) infection

Moyle, P. M., Horvath, A., Olive, C., Good, M. F. and Toth, I. (2003). Development of lipid-core-peptide (LCP) based vaccines for the prevention of the group A streptococcal (GAS) infection. Letters In Peptide Science, 10 (5-6), 605-613. doi: 10.1007/BF02442594

Recombinant Adeno-Associated Virus Vector Tropism in Human Retina

Andrzejewski, Slawomir, Moyle, Peter M., Stringer, Brett W., Steel, Jason and Layton, Christopher J. (2020). Recombinant Adeno-Associated Virus Vector Tropism in Human Retina. In: 23rd Annual Meeting of the American Society for Gene and Cell Therapy, Electr Network, (254-254). 12-15 May 2020.

Effect of human vitreous humour components and neutralising antibodies on transduction activity of recombinant AAV2, AAV5, AAV6 and AAV8

Andrzejewski, S., Moyle, P., Stringer, B., Steel, J. and Layton, C. J. (2019). Effect of human vitreous humour components and neutralising antibodies on transduction activity of recombinant AAV2, AAV5, AAV6 and AAV8. Annual Conference of the British-Society-for-Gene-and-Cell-Therapy, Sheffield, United Kingdom , 19-21 June 2019. New Rochelle, NY, United States: Mary Ann Liebert.

Production of liposomes using supercritical fluid technology and active targeting peptide to a gastrointestinal receptor in cancer cells

Maqbool, Faheem, Moyle, Peter M. and Falconer, James R. (2019). Production of liposomes using supercritical fluid technology and active targeting peptide to a gastrointestinal receptor in cancer cells. Controlled Release Society (CRS), Valencia, Spain, 21-24 July 2019.

Novel preparation of proliposomes with various phospholipids in Supercritical Carbon Dioxide

Maqbool, Faheem, Moyle, Peter M. and Falconer, James R. (2018). Novel preparation of proliposomes with various phospholipids in Supercritical Carbon Dioxide. Controlled Release Society (CRS), New York City, United States, 22-25 July 2018.

A static and gravimetric method for the determination of solubility of Albendazole and its characterization in supercritical carbon dioxide

Maqbool, Faheem, Moyle, Peter M. and Falconer, James R. (2017). A static and gravimetric method for the determination of solubility of Albendazole and its characterization in supercritical carbon dioxide. Drug Delivery Australia (DDA), Wollongong, Australia, 23-24 October 2017.

Vaccine delivery utilizing liposaccharides

Simerska, Pavla, McGeary, Ross P., Abdel-Aal, Abu-Baker M., Moyle, Peter M., Olive, Colleen, Good, Michael F. and Toth, Istvan (2009). Vaccine delivery utilizing liposaccharides. The 20th American Peptide Symposium, Montreal, Canada, 26-30 June, 2007. United States: Springer. doi: 10.1007/978-0-387-73657-0_153

Vaccine delivery: Synthesis and investigation of a highly pure, multi-epitopic lipopeptide vaccine candidate

Toth, Istvan, Moyle, Peter M., Simerska, Pavla, Fujita, Yoshio, Olive, Colleen and Good, Michael F. (2009). Vaccine delivery: Synthesis and investigation of a highly pure, multi-epitopic lipopeptide vaccine candidate. 20th American Peptide Symposium, Montréal, Quebec, Canada, 26-30 June 2007. New York: Springer. doi: 10.1007/978-0-387-73657-0_154

Investigation toward multi-epitope vaccine candidates using native chemical ligation

Fujita, Yoshio, Moyle, Peter M., Hieu, Suzanne, Simerska, Pavla and Toth, Istvan (2008). Investigation toward multi-epitope vaccine candidates using native chemical ligation. Hoboken, NJ, U.S.A.: John Wiley & Sons. doi: 10.1002/bip.21002

Development of a Multivalent Heteroepitopic Group A Streptococcus Vaccine

Fujita, Y., Moyle, P., Abdel-Aal, A., Batzloff, M., Good, M. and Toth, I. (2007). Development of a Multivalent Heteroepitopic Group A Streptococcus Vaccine. 4th International Peptide Symposium, Cairns, 21-25 October 2007. Australia: Australian Peptide Association.

Liposaccharides in Peptide Vaccine Delivery

Simerska, P., Moyle, P. M., Abdel-Aal, A. M., Fujita, Y., Olive, C., Batzloff, M. R., Good, M. F. and Toth, I. (2007). Liposaccharides in Peptide Vaccine Delivery. 4th International Peptide Symposium, Cairns, 21-25 October 2007. Australia: Australian Peptide Association.

Novel lipoamino acid based vaccine adjuvant carrier system

Toth, I., Moyle, P. M., Simerska, P., Fujita, Y., Olive, C. and Good, M. F. (2007). Novel lipoamino acid based vaccine adjuvant carrier system. International Congress of Immunology, Rio de Janeiro, Brazil, 21-25 August 2007. Toronto, Canada: Hogrefe & Huber.

Peptide-lipid-carbohydrate based vaccine against group A Streptococcal infection.

Simerska, P., Abdel-Aal, A. B., McGeary, R., Moyle, P.M., Fujita, Y., Good, M.F. and Toth, I. (2007). Peptide-lipid-carbohydrate based vaccine against group A Streptococcal infection.. 13th International Congress of Immunology, Rio de Janeiro, Brazil, August 21-25.

Vaccine Delivery Utilizing Liposaccharides

Simerska, P., Moyle, P. M., Zhong, W., McGeary, R., Abdel-Aal, A. B., Good, M. F. and Toth, I. (2007). Vaccine Delivery Utilizing Liposaccharides. 20th American Peptide Symposium, Montréal, Quebec, Canada, 26-30 June 2007. Hoboken: John Wiley & Sons. doi: 10.1002/bip.20783

Vaccine delivery: Synthesis and investigation of a highly pure, multi-epitopic lipopeptide vaccine candidate

Toth, I., Moyle, P. M., Simerska, P., Fujita, Y., Olive, C. and Good, M. F. (2007). Vaccine delivery: Synthesis and investigation of a highly pure, multi-epitopic lipopeptide vaccine candidate. 20th American Peptide Symposium, Montréal, Quebec, Canada, 26-30 June 2007. HOBOKEN: Wiley Periodicals. doi: 10.1002/bip.20783

Development of peptide vaccines against HPV-16 associated cervical cancer and group a streptococci

Moyle, Peter M., Horvath, Aniko, Karpati, Levente, Olive, Colleen, Barozzi, Nadia, Wimmer, Norbert, Good, Michael and Toth, Istvan (2006). Development of peptide vaccines against HPV-16 associated cervical cancer and group a streptococci. 19th American Peptide Symposium, San Diego, United States, 18-23 June 2005. New York, United States: Springer. doi: 10.1007/978-0-387-26575-9_169

Development of vaccines for the prevention and/or treatment of human papillomavirus type-16 associated cervical cancer

Simerska, P, Moyle, P. M., Olive, C., Sun, H., Ho, M.-F., Pandy, M.G., Dyer, J. R., Burgess, M L and Toth, I (2006). Development of vaccines for the prevention and/or treatment of human papillomavirus type-16 associated cervical cancer. Brisbane Biological & Organic Chemistry Symposium, Brisbane, 24 November 2006.

Development of vaccines for the prevention and/or treatment of human papillomavirus type-16 associated cervical cancer

Simerska, P., Moyle, P. M., Olive, C., Sun, H. K., Ho, M. F., Pandy, M. G., Dyer, J. R., Burgess, M. L. and Toth, I. (2006). Development of vaccines for the prevention and/or treatment of human papillomavirus type-16 associated cervical cancer. GPEN 2006, Lawrence, USA, 25-27 October, 2006.

Highly pure, multi-epitopic lipopeptide vaccine delivery system: Synthesis and investigation

Moyle, P. M., Olive, C., Ho, M.-F. and Toth, I (2006). Highly pure, multi-epitopic lipopeptide vaccine delivery system: Synthesis and investigation. GPEN 2006, Lawrence, USA, 25 - 27 Oct, 2006.

Highly pure, multi-epitopic lipopeptide vaccine delivery system: Synthesis and investigation

Moyle, P. M., Olive, C., Ho, M.-F., Good, M F and Toth, I (2006). Highly pure, multi-epitopic lipopeptide vaccine delivery system: Synthesis and investigation. Brisbane Biological & Organic Chemistry Symposium, Brisbane, 24 Nov 2006.

Liposaccharide based vaccine carrier adjuvant systems

Simerska, P., Bong, Y. K., McGeary, R. P., Moyle, P. M. and Toth, I. (2006). Liposaccharide based vaccine carrier adjuvant systems. Drug Design Amongst the Vines, Hunter Valley, 3 - 7 December 2006.

Liposaccharides in peptide, gene and vaccine delivery

Toth, I., Moyle, P. M., Simerska, P., Fujita, Y., Olive, C. and Good, M. F. (2006). Liposaccharides in peptide, gene and vaccine delivery. Drug Design Amongst the Vines, Hunter Valley, 3 - 7 December, 2006.

Liposaccharides in peptide, gene and vaccine delivery

Toth, I, Moyle, P. M., Koda, Y., Olive, C. and Good, M F (2006). Liposaccharides in peptide, gene and vaccine delivery. 10th Naples Workshop on Bioactive Peptides, Naples, 11-14 June, 2006.

Liposaccharides in peptide, gene and vaccine delivery

Toth, I., Moyle, P. M., Koda, Y., Olive, C. and Good, M. F. (2006). Liposaccharides in peptide, gene and vaccine delivery. 33rd Annual Meeting and Exposition of the Controlled Release Soy, Vienna, 22-26 July, 2006.

Multi-epitopic lipid core peptide vaccine with broad protective immune responses against Group A Streptococcus

Fujita, Y., Moyle, P., Olive, C., Good, M. and Toth, I. (2006). Multi-epitopic lipid core peptide vaccine with broad protective immune responses against Group A Streptococcus. CHICHESTER: JOHN WILEY & SONS LTD.

Multi-epitopic lipid core peptide vaccine with broad protective immune responses against Group A streptococcus

Fujita, Y, Moyle, P. M., Olive, C., Good, M F and Toth, I (2006). Multi-epitopic lipid core peptide vaccine with broad protective immune responses against Group A streptococcus. 29th European Peptide Symposium, Gdansk, 3-8 Sept, 2006.

Synthesis and immunological evaluation of M protein targeted tetra-valent and tri-valent group A streptococcal vaccine candidates based on the lipid-core peptide system

Moyle, Peter Michael, Olive, Colleen, Karpati, Levente, Barozzi, Nadia, Ho, Mei-Fong, Dyer, Joanne, Sun, Hsien Kuo, Good, Michael and Toth, Istvan (2006). Synthesis and immunological evaluation of M protein targeted tetra-valent and tri-valent group A streptococcal vaccine candidates based on the lipid-core peptide system. 6th Australian Peptide Conference, Whitsunday Islands, Australia, 9-14 October, 2005. Netherlands: Springer. doi: 10.1007/s10989-006-9021-8

The lipid core peptide system in vaccine delivery

Toth, I., Moyle, P. M., Karpati, L., Horvath, A., Olive, C. and Good, M. F. (2006). The lipid core peptide system in vaccine delivery. XVIth Lancefield International Symposium on Streptococci and Streptococcal Diseases, Palm Cove, Australia, 25 and 29 September 2005. Amsterdam, The Netherlands: Excerpta Medica Foundation. doi: 10.1016/j.ics.2005.11.057

The synthesis and immunological activity of a lipid-core peptide (LCP) based Human Papillomavirus (HPV) type-16 vaccine

Moyle, Peter M., Olive, Colleen, Sun, Hsien, Good, Michael and Toth, Istvan (2005). The synthesis and immunological activity of a lipid-core peptide (LCP) based Human Papillomavirus (HPV) type-16 vaccine. 3rd International Peptide Symposium and 28th European Peptide Symposium, Prague, Czech Republic, 5-10 September 2004. GENEVA 1: Kenes International.

Liposaccharides for drug and vaccine delivery

Toth, I., Horvath, A., Karpati, L., Moyle, P., Olive, C. and Good, M. (2004). Liposaccharides for drug and vaccine delivery. 3rd International and 28th European Peptide Symposium, Prague, Czech Republic, 5–10 September 2004. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.618

Solid-phase synthesis of oligosaccharides utilising a novel Dde-based linker

Moyle, P.M., Mcgeary, R. P. and Toth, I. (2001). Solid-phase synthesis of oligosaccharides utilising a novel Dde-based linker. APSA Annual Conference 2001, Melbourne, 9-12 Dec 2001. Melbourne: Australasian Pharmaceutical Science Association.

Vaccine-adjuvant-carrier design against group A streptococcus and human papillomavirus type-16 infection

Moyle, Peter Michael (2006). Vaccine-adjuvant-carrier design against group A streptococcus and human papillomavirus type-16 infection. PhD Thesis, School of Pharmacy, The University of Queensland.