Dr Zyta M Ziora

Senior Research Officer

Institute for Molecular Bioscience
z.ziora@imb.uq.edu.au
+61 7 334 62202

Overview

Dr Zyta Ziora received PhD (Wroclaw University of Science & Technology, Poland) in chemistry and has wide range of experience in development of antimalarial therapeutics (the University of Montpellier, France), antibacterial agents, enzyme inhibitors and drug candidates against Alzheimer disease (Kyoto Pharmaceutical University, Japan). Her research time is currently dedicated mainly to projects devoted to the modification of existing antibiotics, and complexing them with additional antimicrobial agents, like metal ions, to produce more potent alternatives and by this to overcome the drug resistance of superbugs. She is also working on alternative to antibiotics nature-derived compounds with antimicrobial and anticancer potency, such poliphenolic derivatives to control tyrosinase function.

Research Interests

  • Researcher and Lecturer in Biotechnology & Molecular Biology Programs
    Modification of existing antibiotics – complexing with metal ions Alternative to antibiotics – nature-derived compounds with antimicrobial and anticancer potency Tyrosinase inhibition – potential treatment for skin bacterial infections and melanoma prevention

Research Impacts

The International Science Seminar Series (ISS) supports UQ-IITD PhD students to be virtually connected and have an opportunity to broaden their scientific horizons. Please visit the ISS website if you wish to watch previous sessions or if you would like to participate and subscribe to the ISS series. View the padlet online.

Qualifications

  • Doctor of Philosophy, Wroclaw
  • Master of Science, Wroclaw

Publications

View all Publications

Supervision

  • Doctor Philosophy

  • Doctor Philosophy

  • Doctor Philosophy

View all Supervision

Available Projects

View all Available Projects

Publications

Book Chapter

  • Mital, Mariusz, Sęk, Jakub P. and Ziora, Zyta M. (2020). Metal-peptide complexes to study neurodegenerative diseases. Peptide synthesis: methods and protocols. (pp. 323-336) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-0227-0_22

  • Hamada, Yoshio and Ziora, Zyta M. (2020). Peptidomimetic synthesis: drug discovery for Alzheimer's disease. Peptide synthesis: methods and protocols. (pp. 215-223) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-0227-0_14

  • Hansford, Karl A., Ziora, Zyta M., Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). Solid-phase synthesis of octapeptin lipopeptides. Peptide synthesis: methods and protocols. (pp. 199-213) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-0227-0_13

  • Ziora, Zyta, Skwarczynski, Mariusz and Kiso, Yoshiaki (2011). Medicinal chemistry of a-hydroxy-b-amino acids. Amino Acids, Peptides and Proteins in Organic Chemistry: Volume 4 - Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis. (pp. 189-234) edited by Andrew B. Hughes. Weinheim, Germany: Wiley-VCH. doi: 10.1002/9783527631827.ch6

Journal Article

Conference Publication

  • Skwarczynski, Mariusz, Liu, Tzu-Yu, Hussein, Waleed M., Jia, Zhongfan, Ziora, Zyta M., McMillan, Nigel A. J., Monteiro, Michael J. and Toth, Istvan (2014). Synthesis of therapeutic vaccine against cervical cancer. 4th Asia-Pacific International Peptide Symposium in conjunction with 50th Japanese Peptide Symposium, Osaka, Japan, 6-8 November 2013. Osaka, Japan: Japanese Peptide Society.

  • Skwarczynski, M., Fuaad, A. A. H. A., Zaman, M., Jia, Z., Kowapradit, J., Rustanti, L., Ziora, Z. M., Monteiro, M. L. J., Batzloff, M. R., Goodc, M. F. and Toth, I. (2012). Nanoparticles-based peptide subunit vaccines against group A Streptococcus. 32nd European Peptide Symposium, Athens, Greece, 2-7 September 2012. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.2448

  • Gong, Y., Muldoon, C. A., Premraj, R., Ziora, Z. M., Bradford, T. A., Cheng, M., Ramu, S., Huang, J. X., Kavanagh, A., Pelingon, R., Lee, J. C., Wong, K., Butler, M. S., Blaskovich, M. A. and Cooper, M. A. (2012). New glycopeptidic antibiotics to combat multidrug resistant pathogens. 32nd European Peptide Symposium, Athens, Greece, 2-7 September 2012. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.2449

  • Ziora, Zyta, Shuto, Daisuke, Kasai, Soko, Liu, Ping, Hidaka, Koushi, Igawa, Nagai, Nagamine, Ayaka, Stochaj, Monika, Hamada, Takashi, Kimura, Tooru, Hayashi, Yoshio and Kiso, Yoshiaki (2006). Modification of P4 position in beta-Secretase (BACE1) inhibitors containing phenylnorstatine. 42nd Japanese Peptide Symposium, Osaka, Japan, 27-29 October 2005. Osaka, Japan: Japanese Peptide Society.

  • Sohma, Youhei, Sasaki, Masato, Ziora, Zyta, Takahashi, N., Kimura, Tooru, Hayashi, Yoshio and Kiso, Yoshiaki (2004). A novel approach for the hydrophobic peptides synthesis and purification through O-N intramolecular acyl migration reaction. 18th American Peptide Symposium, Boston, MA, U.S.A., 19-23 July 2003. San Diego, CA, U.S.A.: American Peptide Society.

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

    Other advisors:

Completed Supervision

Possible Research Projects

Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.