The University of Queensland

Hyperbranched polymers as nanocarriers

Houston, Zachary H., Bell, Craig A. and Thurecht, Kristofer J. (2018). Hyperbranched polymers as nanocarriers. Encyclopedia of polymer science and technology. (pp. 1-27) Hoboken, NJ USA: John Wiley & Sons. doi: 10.1002/0471440264.pst159.pub2

Molecular imaging utilizing aptamer-targeted probes

Fletcher, Nicholas and Thurechta, Kristofer (2016). Molecular imaging utilizing aptamer-targeted probes. Aptamers: tools for nanotherapy and molecular imaging. (pp. 287-317) edited by Rakesh N. Veedu. Singapore: Pan Stanford Publishing. doi: 10.1201/b20047-11

Reversible addition fragmentation chain transfer (RAFT) polymerization: mechanism, process and applications

Barner-Kowollik, Christopher, Blinco, James P., Destarac, Mathias, Thurecht, Kristofer J. and Perrier, Sébastien (2012). Reversible addition fragmentation chain transfer (RAFT) polymerization: mechanism, process and applications. Encyclopedia of radicals in chemistry, biology and materials. (pp. 1895-1929) edited by Chryssostomos Chatgilialoglu and Armido Studer. Chichester, West Sussex, U.K.: John Wiley & Sons. doi: 10.1002/9781119953678.rad058

Effect of molecular architecture on the performance of (19)F NMR imaging agents

Peng, Hui, Thurecht, Kristofer, Hsu, Steven, Blakey, Idriss, Squires, Oliver, Kurniawan, Nyoman, Rose, Stephen and Whittaker, Andrew (2011). Effect of molecular architecture on the performance of (19)F NMR imaging agents. NMR Spectroscopy of Polymers: Innovative Strategies for Complex Macromolecules. (pp. 459-472) edited by H. N. Cheng, Tetsuo Asakur and Alan D. English. Washington, DC, United States: American Chemical Society. doi: 10.1021/bk-2011-1077.ch028

Biocatalytic Polymerization in Exotic Solvents

Thurecht, Kristofer James and Villarroya, Silvia (2010). Biocatalytic Polymerization in Exotic Solvents. Biocatalysis in Polymer Chemistry. (pp. 323-348) edited by Katja Loos. Weinheim, Germany: Wiley - V C H Verlag GmbH & Co. KGaA. doi: 10.1002/9783527632534

Multifunctional Fluoropolymer‐Engineered Magnetic Nanoparticles to Facilitate Blood‐Brain Barrier Penetration and Effective Gene Silencing in Medulloblastoma

Forgham, Helen, Zhu, Jiayuan, Huang, Xumin, Zhang, Cheng, Biggs, Heather, Liu, Liwei, Wang, Yi Cheng, Fletcher, Nicholas, Humphries, James, Cowin, Gary, Mardon, Karine, Kavallaris, Maria, Thurecht, Kristofer, Davis, Thomas P. and Qiao, Ruirui (2024). Multifunctional Fluoropolymer‐Engineered Magnetic Nanoparticles to Facilitate Blood‐Brain Barrier Penetration and Effective Gene Silencing in Medulloblastoma. Advanced Science. doi: 10.1002/advs.202401340

EGFR Targeting of Liposomal Doxorubicin Improves Recognition and Suppression of Non-Small Cell Lung Cancer

Moles, Ernest, Chang, David, Mansfeld, Friederike, Duly, Alastair, Kimpton, Kathleen, Logan, Amy, Howard, Christopher, Thurecht, Kristofer and Kavallaris, Maria (2024). EGFR Targeting of Liposomal Doxorubicin Improves Recognition and Suppression of Non-Small Cell Lung Cancer. International Journal of Nanomedicine, Volume 19, 3623-3639. doi: 10.2147/ijn.s450534

Targeted delivery of polo-like kinase 1 siRNA nanoparticles using an EGFR-PEG bispecific antibody inhibits proliferation of high-risk neuroblastoma

Logan, Amy, Howard, Christopher B., Huda, Pie, Kimpton, Kathleen, Ma, Zerong, Thurecht, Kristofer J., McCarroll, Joshua A., Moles, Ernest and Kavallaris, Maria (2024). Targeted delivery of polo-like kinase 1 siRNA nanoparticles using an EGFR-PEG bispecific antibody inhibits proliferation of high-risk neuroblastoma. Journal of Controlled Release, 367, 806-820. doi: 10.1016/j.jconrel.2024.02.007

Biodegradable mPEG-<i>b</i>-poly(MDO-<i>co</i>-vinyl esters) block copolymers as a viable nanocarrier platform with tuneable disassembly

Balaji, Arunpandian, Prior, Amber R., O'Reilly, Rachel K., Dove, Andrew P., Thurecht, Kristofer J. and Bell, Craig A. (2024). Biodegradable mPEG-b-poly(MDO-co-vinyl esters) block copolymers as a viable nanocarrier platform with tuneable disassembly. Polymer Chemistry, 15 (12), 1152-1165. doi: 10.1039/d4py00049h

Abstract A147: a HER2 targeted polylysine dendrimer nanoparticle radiotheranostic demonstrates excellent tumor accumulation, rapid clearance from circulation, and promising performance in PET-CT imaging

Johnstone, Cameron N., Heery, Graham P., Kelly, Brian D, Humphries, James, Akhter, Dewan T., Thurecht, Kristofer J., Yuen, Daniel, Giannis, Michael, Yong, Ken, Chadwick, Gareth, Barker, Helena, Cargill, Anne, Eglezos, Anthony, Castellarnau, Alex, Paull, Jeremy R. A. and Hufton, Richard (2023). Abstract A147: a HER2 targeted polylysine dendrimer nanoparticle radiotheranostic demonstrates excellent tumor accumulation, rapid clearance from circulation, and promising performance in PET-CT imaging. Molecular Cancer Therapeutics, 22 (12_Supplement), A147-A147. doi: 10.1158/1535-7163.targ-23-a147

Self-cyclisation as a general and efficient platform for peptide and protein macrocyclisation

Jia, Xinying, Chin, Yanni K.-Y., Zhang, Alan H., Crawford, Theo, Zhu, Yifei, Fletcher, Nicholas L., Zhou, Zihan, Hamilton, Brett R., Stroet, Martin, Thurecht, Kristofer J. and Mobli, Mehdi (2023). Self-cyclisation as a general and efficient platform for peptide and protein macrocyclisation. Communications Chemistry, 6 (1) 48, 1-10. doi: 10.1038/s42004-023-00841-5

Targeted hyperbranched nanoparticles for delivery of doxorubicin in breast cancer brain metastasis

Lim, Malcolm, Fletcher, Nicholas L., Saunus, Jodi M., McCart Reed, Amy E., Chittoory, Haarika, Simpson, Peter T., Thurecht, Kristofer J. and Lakhani, Sunil R. (2023). Targeted hyperbranched nanoparticles for delivery of doxorubicin in breast cancer brain metastasis. Molecular Pharmaceutics, 20 (12), 6169-6183. doi: 10.1021/acs.molpharmaceut.3c00558

An immunomodulating peptide with potential to suppress tumour growth and autoimmunity

Agrez, Michael, Chandler, Christopher, Thurecht, Kristofer J., Fletcher, Nicholas L., Liu, Feifei, Subramaniam, Gayathri, Howard, Christopher B., Blyth, Benjamin, Parker, Stephen, Turner, Darryl, Rzepecka, Justyna, Knox, Gavin, Nika, Anastasia, Hall, Andrew M., Gooding, Hayley and Gallagher, Laura (2023). An immunomodulating peptide with potential to suppress tumour growth and autoimmunity. Scientific Reports, 13 (1) 19741, 19741. doi: 10.1038/s41598-023-47229-y

Exploring the impact of severity in hepatic fibrosis disease on the intrahepatic distribution of novel biodegradable nanoparticles targeted towards different disease biomarkers

Balaji, Arunpandian, Bell, Craig A., Houston, Zachary H., Bridle, Kim R., Genz, Berit, Fletcher, Nicholas L., Ramm, Grant A. and Thurecht, Kristofer J. (2023). Exploring the impact of severity in hepatic fibrosis disease on the intrahepatic distribution of novel biodegradable nanoparticles targeted towards different disease biomarkers. Biomaterials, 302 122318, 1-18. doi: 10.1016/j.biomaterials.2023.122318

Click‐on antibody fragments for customisable targeted nanomedicines – site‐specific tetrazine and azide functionalisation through non‐canonical amino acid incorporation

Huda, Pie, Humphries, James, Fletcher, Nicholas L., Howard, Christopher B., Thurecht, Kristofer J. and Bell, Craig A. (2023). Click‐on antibody fragments for customisable targeted nanomedicines – site‐specific tetrazine and azide functionalisation through non‐canonical amino acid incorporation. Chemistry–Methods, 4 (2). doi: 10.1002/cmtd.202300036

An immunomodulating peptide to counteract solar radiation-induced immunosuppression and DNA damage

Agrez, Michael, Rybchyn, Mark Stephen, De Silva, Warusavithana Gunawardena Manori, Mason, Rebecca Sara, Chandler, Christopher, Piva, Terrence J., Thurecht, Kristofer, Fletcher, Nicholas, Liu, Feifei, Subramaniam, Gayathri, Howard, Christopher B., Blyth, Benjamin, Parker, Stephen, Turner, Darryl, Rzepecka, Justyna, Knox, Gavin, Nika, Anastasia, Hall, Andrew, Gooding, Hayley and Gallagher, Laura (2023). An immunomodulating peptide to counteract solar radiation-induced immunosuppression and DNA damage. Scientific Reports, 13 (1) 11702, 1-19. doi: 10.1038/s41598-023-38890-4

RAFT polymer–antibody conjugation: squaramide ester chemistry leads to conjugates with a therapeutic anti-EGFR antibody with full retention of activity and increased tumor uptake in vivo

Ardana, Aditya, Ghosh, Saikat, Huda, Pie, Fletcher, Nicholas L., Thurecht, Kristofer J. and Williams, Charlotte C. (2023). RAFT polymer–antibody conjugation: squaramide ester chemistry leads to conjugates with a therapeutic anti-EGFR antibody with full retention of activity and increased tumor uptake in vivo. Molecular Pharmaceutics, 20 (6), 3073-3087. doi: 10.1021/acs.molpharmaceut.3c00085

Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia

Moles, Ernest, Howard, Christopher B., Huda, Pie, Karsa, Mawar, McCalmont, Hannah, Kimpton, Kathleen, Duly, Alastair, Chen, Yongjuan, Huang, Yizhou, Tursky, Melinda L., Ma, David, Bustamante, Sonia, Pickford, Russell, Connerty, Patrick, Omari, Sofia, Jolly, Christopher J., Joshi, Swapna, Shen, Sylvie, Pimanda, John E., Dolnikov, Alla, Cheung, Laurence C., Kotecha, Rishi S., Norris, Murray D., Haber, Michelle, de Bock, Charles E., Somers, Klaartje, Lock, Richard B., Thurecht, Kristofer J. and Kavallaris, Maria (2023). Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia. Science Translational Medicine, 15 (696) abm1262, 1-17. doi: 10.1126/scitranslmed.abm1262

Development and validation of a targeted treatment for brain tumors using a multi-drug loaded, relapse-resistant polymeric theranostic

Chu, Weijing, Houston, Zachary H., Fletcher, Nicholas L., Huda, Pie, Ahamed, Muneer, Lim, Ting Xiang, Day, Bryan W., Pinkham, Mark and Thurecht, Kristofer J. (2023). Development and validation of a targeted treatment for brain tumors using a multi-drug loaded, relapse-resistant polymeric theranostic. Biomacromolecules, 24 (6), 2674-2690. doi: 10.1021/acs.biomac.3c00138

Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma

Janjua, Taskeen Iqbal, Cao, Yuxue, Ahmed-Cox, Aria, Raza, Aun, Moniruzzaman, Md, Akhter, Dewan Taslima, Fletcher, Nicholas L., Kavallaris, Maria, Thurecht, Kristofer J. and Popat, Amirali (2023). Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma. Journal of Controlled Release, 357, 161-174. doi: 10.1016/j.jconrel.2023.03.040

Combination of chemotherapy and mild hyperthermia using targeted nanoparticles: a potential treatment modality for breast cancer

Kaur, Ishdeep, Tieu, Terence, Deepagan, Veerasikku G., Ali, Muhammad A., Alsunaydih, Fahad, Rudd, David, Moghaddam, Maliheh A., Bourgeois, Laure, Adams, Timothy E., Thurecht, Kristofer J., Yuce, Mehmet, Cifuentes-Rius, Anna and Voelcker, Nicolas H. (2023). Combination of chemotherapy and mild hyperthermia using targeted nanoparticles: a potential treatment modality for breast cancer. Pharmaceutics, 15 (5) 1389, 1-23. doi: 10.3390/pharmaceutics15051389

Homochiral poly(2‐oxazoline)‐based membrane for efficient enantioselective separation

Wang, Fanmengjing, Pizzi, David, Lu, Yizhihao, He, Kaiqiang, Thurecht, Kristofer J., Hill, Matthew R., Marriott, Philip, Holl, Mark M. Banaszak, Kempe, Kristian and Wang, Huanting (2023). Homochiral poly(2‐oxazoline)‐based membrane for efficient enantioselective separation. Angewandte Chemie International Edition, 62 (8) e202212139, 1-6. doi: 10.1002/anie.202212139

Pharmacokinetics and Biodistribution of Zr-Miltuximab and Its Antibody Fragments as Glypican-1 Targeting Immuno-PET Agents in Glioblastoma

Ghosh, Saikat, Fletcher, Nicholas L., Huda, Pie, Houston, Zachary H., Howard, Christopher B., Lund, Maria E., Lu, Yanling, Campbell, Douglas H., Walsh, Bradley J. and Thurecht, Kristofer J. (2023). Pharmacokinetics and Biodistribution of Zr-Miltuximab and Its Antibody Fragments as Glypican-1 Targeting Immuno-PET Agents in Glioblastoma. Molecular pharmaceutics, 20 (3), 1549-1563. doi: 10.1021/acs.molpharmaceut.2c00760

Enhanced drug delivery to cancer cells through a pH-sensitive polycarbonate platform

Arno, Maria C., Simpson, Joshua D., Blackman, Lewis D., Brannigan, Ruairí P., Thurecht, Kristofer J. and Dove, Andrew P. (2023). Enhanced drug delivery to cancer cells through a pH-sensitive polycarbonate platform. Biomaterials Science, 11 (3), 908-915. doi: 10.1039/d2bm01626e

Utilizing PET and MALDI imaging for discovery of a targeted probe for brain endocannabinoid α/β-hydrolase domain 6 (ABHD6)

Mardon, Karine, Patel, Jayendra Z., Savinainen, Juha R., Stimson, Damion H. R., Oyagawa, Caitlin R. M., Grimsey, Natasha L., Migotto, Mary-anne, Njiru, Grace F. M., Hamilton, Brett R., Cowin, Gary, Yli-Kauhaluoma, Jari, Vanduffel, Wim, Blakey, Idriss, Bhalla, Rajiv, Cawthorne, Christopher, Celen, Sofie, Bormans, Guy, Thurecht, Kristofer J and Ahamed, Muneer (2022). Utilizing PET and MALDI imaging for discovery of a targeted probe for brain endocannabinoid α/β-hydrolase domain 6 (ABHD6). Journal of Medicinal Chemistry, 66 (1), 538-552. doi: 10.1021/acs.jmedchem.2c01485

Probing the biocompatibility and immune cell association of chiral, water-soluble, bottlebrush poly(2-oxazoline)s

Pizzi, David, Humphries, James, Morrow, Joshua P., Mahmoud, Ayaat M., Fletcher, Nicholas L., Sonderegger, Stefan E., Bell, Craig A., Thurecht, Kristofer J. and Kempe, Kristian (2022). Probing the biocompatibility and immune cell association of chiral, water-soluble, bottlebrush poly(2-oxazoline)s. Biomacromolecules, 24 (1), 246-257. doi: 10.1021/acs.biomac.2c01105

Modulating macrophage clearance of nanoparticles: comparison of small-molecule and biologic drugs as pharmacokinetic modifiers of soft nanomaterials

Mills, Jessica A., Humphries, James, Simpson, Joshua D., Sonderegger, Stefan E., Thurecht, Kristofer J. and Fletcher, Nicholas L. (2022). Modulating macrophage clearance of nanoparticles: comparison of small-molecule and biologic drugs as pharmacokinetic modifiers of soft nanomaterials. Molecular Pharmaceutics, 19 (11), 4080-4097. doi: 10.1021/acs.molpharmaceut.2c00528

Modeling brain metastasis by internal carotid artery injection of cancer cells

Lim, Malcolm, Fletcher, Nicholas, Reed, Amy Mccart, Flint, Melanie, Thurecht, Kristofer, Saunus, Jodi and Lakhani, Sunil R. (2022). Modeling brain metastasis by internal carotid artery injection of cancer cells. Journal of Visualized Experiments, 2022 (186) e64216. doi: 10.3791/64216

Protected amine-functional initiators for the synthesis of α-amine homo- and heterotelechelic poly(2-ethyl-2-oxazoline)s

Mazrad, Zihnil A. I., Lai, May, Davis, Thomas P., Nicolazzo, Joseph A., Thurecht, Kristofer J., Leiske, Meike N. and Kempe, Kristian (2022). Protected amine-functional initiators for the synthesis of α-amine homo- and heterotelechelic poly(2-ethyl-2-oxazoline)s. Polymer Chemistry, 13 (30), 4436-4445. doi: 10.1039/d2py00649a

A novel lipidic peptide with potential to promote balanced effector-regulatory T cell responses

Agrez, Michael, Rzepecka, Justyna, Turner, Darryl, Knox, Gavin, Chandler, Christopher, Howard, Christopher B., Fletcher, Nicholas, Thurecht, Kristofer, Parker, Stephen, Gooding, Hayley and Gallagher, Laura (2022). A novel lipidic peptide with potential to promote balanced effector-regulatory T cell responses. Scientific Reports, 12 (1) 11185, 11185. doi: 10.1038/s41598-022-15455-5

Confined microemulsion sono-polymerization of poly(ethylene glycol) nanoparticles for targeted delivery

Gao, Zhiliang, Li, Xiaoyu, Zhao, Kaijie, Geng, Huimin, Zhang, Peiyu, Ju, Yi, Huda, Pie, Howard, Christopher B, Thurecht, Kristofer J, Ashokkumar, Muthupandian, Hao, Jingcheng and Cui, Jiwei (2022). Confined microemulsion sono-polymerization of poly(ethylene glycol) nanoparticles for targeted delivery. Chemical Communications, 58 (56), 7777-7780. doi: 10.1039/d2cc01874h

Pre-targeting of polymeric nanomaterials to balance tumour accumulation and clearance

Fletcher, N. L., Prior, A., Choy, O., Humphries, J., Huda, P., Ghosh, S., Houston, Z. H., Bell, C. A. and Thurecht, K. J. (2022). Pre-targeting of polymeric nanomaterials to balance tumour accumulation and clearance. Chemical Communications, 58 (57), 7912-7915. doi: 10.1039/d2cc02443h

Development of targeted micelles and polymersomes prepared from degradable RAFT-based diblock copolymers and their potential role as nanocarriers for chemotherapeutics

Ahmed, Salma E., Fletcher, Nicholas L., Prior, Amber R., Huda, Pie, Bell, Craig A. and Thurecht, Kristofer J. (2022). Development of targeted micelles and polymersomes prepared from degradable RAFT-based diblock copolymers and their potential role as nanocarriers for chemotherapeutics. Polymer Chemistry, 13 (27), 4004-4017. doi: 10.1039/d2py00257d

Investigation of a dual siRNA/chemotherapy delivery system for breast cancer therapy

Zhao, Yongmei, Liu, Tianqing, Ardana, Aditya, Fletcher, Nicholas L., Houston, Zachary H., Blakey, Idriss and Thurecht, Kristofer J. (2022). Investigation of a dual siRNA/chemotherapy delivery system for breast cancer therapy. ACS Omega, 7 (20), 17119-17127. doi: 10.1021/acsomega.2c00620

Antibody-based formats to target glioblastoma: overcoming barriers to protein drug delivery

Ghosh, Saikat, Huda, Pie, Fletcher, Nicholas L., Howard, Christopher B., Walsh, Bradley, Campbell, Douglas, Pinkham, Mark B. and Thurecht, Kristofer J. (2022). Antibody-based formats to target glioblastoma: overcoming barriers to protein drug delivery. Molecular Pharmaceutics, 19 (5), 1233-1247. doi: 10.1021/acs.molpharmaceut.1c00996

Template-assisted antibody assembly: a versatile approach for engineering functional antibody nanoparticles

Hu, Yingjie, Li, Jianhua, Ju, Yi, Houston, Zachary H., Fletcher, Nicholas L., De Rose, Robert, Fernandes, Soraia, Hagemeyer, Christoph E., Alt, Karen, Thurecht, Kristofer J., Cortez-Jugo, Christina and Caruso, Frank (2022). Template-assisted antibody assembly: a versatile approach for engineering functional antibody nanoparticles. Chemistry of Materials, 34 (8) acs.chemmater.1c04397, 3694-3704. doi: 10.1021/acs.chemmater.1c04397

Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption

Janowicz, Phillip W., Houston, Zachary H., Bunt, Jens, Fletcher, Nicholas L., Bell, Craig A., Cowin, Gary, Howard, Christopher B., Taslima, Dewan, Westra van Holthe, Nicholas, Prior, Amber, Soh, Vanessa, Ghosh, Saikat, Humphries, James, Huda, Pie, Mahler, Stephen M., Richards, Linda J. and Thurecht, Kristofer J. (2022). Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption. Biomaterials, 283 121416, 121416. doi: 10.1016/j.biomaterials.2022.121416

Simultaneous dual echo gadolinium enhanced MR-PET for evaluation of PET tracer delivery in altered pathophysiology

Cowin, Gary J, Mardon, Karine, Houston, Zachary H., Bhalla, Rajiv, Stimson, Damion H. R., Thurecht, Kristofer J. and Brereton, Ian M. (2022). Simultaneous dual echo gadolinium enhanced MR-PET for evaluation of PET tracer delivery in altered pathophysiology. Frontiers in Physics, 10 759749. doi: 10.3389/fphy.2022.759749

Clinical development of an anti-GPC-1 antibody for the treatment of cancer

Ghosh, Saikat, Huda, Pie, Fletcher, Nicholas, Campbell, Douglas, Thurecht, Kristofer J. and Walsh, Bradley (2022). Clinical development of an anti-GPC-1 antibody for the treatment of cancer. Expert Opinion on Biological Therapy, 22 (5), 603-613. doi: 10.1080/14712598.2022.2033204

Nanoparticle based medicines: approaches for evading and manipulating the mononuclear phagocyte system and potential for clinical translation

Mills, Jessica A., Liu, Feifei, Jarrett, Thomas R., Fletcher, Nicholas L. and Thurecht, Kristofer J. (2022). Nanoparticle based medicines: approaches for evading and manipulating the mononuclear phagocyte system and potential for clinical translation. Biomaterials Science, 10 (12), 3029-3053. doi: 10.1039/d2bm00181k

Synthesis, characterisation and evaluation of hyperbranched N-(2-hydroxypropyl) methacrylamides for transport and delivery in pancreatic cell lines in vitro and in vivo

Anane-Adjei, Akosua B., Fletcher, Nicholas L., Cavanagh, Robert J., Houston, Zachary H., Crawford, Theodore, Pearce, Amanda K., Taresco, Vincenzo, Ritchie, Alison A., Clarke, Phillip, Grabowska, Anna M., Gellert, Paul R., Ashford, Marianne B., Kellam, Barrie, Thurecht, Kristofer J. and Alexander, Cameron (2022). Synthesis, characterisation and evaluation of hyperbranched N-(2-hydroxypropyl) methacrylamides for transport and delivery in pancreatic cell lines in vitro and in vivo. Biomaterials Science, 10 (9), 2328-2344. doi: 10.1039/d1bm01548f

Development of enteric-coated, biphasic chitosan/HPMC microcapsules for colon-targeted delivery of anticancer drug-loaded nanoparticles

Ma, Yiming, Thurecht, Kristofer J. and Coombes, Allan G.A. (2021). Development of enteric-coated, biphasic chitosan/HPMC microcapsules for colon-targeted delivery of anticancer drug-loaded nanoparticles. International Journal of Pharmaceutics, 607 121026, 121026. doi: 10.1016/j.ijpharm.2021.121026

Cyanine-5-driven behaviours of hyperbranched polymers designed for therapeutic delivery are cell-type specific and correlated with polar lipid distribution in membranes

Simpson, Joshua D., Currin-Ross, Denni L., Ediriweera, Gayathri R., Schirra, Horst Joachim, Fletcher, Nicholas L., Bell, Craig A., Arno, Maria C. and Thurecht, Kristofer J. (2021). Cyanine-5-driven behaviours of hyperbranched polymers designed for therapeutic delivery are cell-type specific and correlated with polar lipid distribution in membranes. Nanomaterials, 11 (7) 1745, 1-18. doi: 10.3390/nano11071745

Interactions of core cross-linked poly(2-oxazoline) and poly(2-oxazine) micelles with immune cells in human blood

Leiske, Meike N., Lai, May, Amarasena, Thakshila, Davis, Thomas P., Thurecht, Kristofer J., Kent, Stephen J. and Kempe, Kristian (2021). Interactions of core cross-linked poly(2-oxazoline) and poly(2-oxazine) micelles with immune cells in human blood. Biomaterials, 274 120843, 120843. doi: 10.1016/j.biomaterials.2021.120843

Evaluation of the in vivo fate of ultrapure alginate in a BALB/c mouse model

A, Anitha, Fletcher, Nicholas L., Houston, Zachary H., Thurecht, Kristofer J. and Grøndahl, Lisbeth (2021). Evaluation of the in vivo fate of ultrapure alginate in a BALB/c mouse model. Carbohydrate Polymers, 262 117947, 117947. doi: 10.1016/j.carbpol.2021.117947

Non-viral vector-mediated gene therapy for ALS: challenges and future perspectives

Ediriweera, Gayathri R., Chen, Liyu, Yerbury, Justin J., Thurecht, Kristofer J. and Vine, Kara L. (2021). Non-viral vector-mediated gene therapy for ALS: challenges and future perspectives. Molecular Pharmaceutics, 18 (6), 2142-2160. doi: 10.1021/acs.molpharmaceut.1c00297

Poly(2-ethyl-2-oxazoline) bottlebrushes: How nanomaterial dimensions can influence biological interactions

Pizzi, David, Mahmoud, Ayaat M., Klein, Tobias, Morrow, Joshua P., Humphries, James, Houston, Zachary H., Fletcher, Nicholas L., Bell, Craig A., Thurecht, Kristofer J. and Kempe, Kristian (2021). Poly(2-ethyl-2-oxazoline) bottlebrushes: How nanomaterial dimensions can influence biological interactions. European Polymer Journal, 151 110447, 1-9. doi: 10.1016/j.eurpolymj.2021.110447

Celebrating women in the pharmaceutical sciences

Taylor, Lynne S., Bergström, Christel A. S., Lavasanifar, Afsaneh, Qian, Feng, Suryanarayanan, Raj and Thurecht, Kristofer J. (2021). Celebrating women in the pharmaceutical sciences. Molecular Pharmaceutics, 18 (4) acs.molpharmaceut.0c01197, 1487-1490. doi: 10.1021/acs.molpharmaceut.0c01197

Fluorophore selection and incorporation contribute to permeation and distribution behaviors of hyperbranched polymers in multi-cellular tumor spheroids and xenograft tumor models

Simpson, Joshua D., Monteiro, Patrícia F., Ediriweera, Gayathri R., Prior, Amber R., Sonderegger, Stefan E., Bell, Craig A., Fletcher, Nicholas L., Alexander, Cameron and Thurecht, Kristofer J. (2021). Fluorophore selection and incorporation contribute to permeation and distribution behaviors of hyperbranched polymers in multi-cellular tumor spheroids and xenograft tumor models. ACS Applied Bio Materials, 4 (3) acsabm.0c01616, 2675-2685. doi: 10.1021/acsabm.0c01616

Characterization of the biodistribution of a silica vesicle Nanovaccine carrying a Rhipicephalus (Boophilus) microplus protective antigen with in vivo live animal imaging

Mody, Karishma T., Zhang, Bing, Li, Xun, Fletcher, Nicholas L., Akhter, Dewan T., Jarrett, Sandy, Zhang, Jun, Yu, Chengzhong, Thurecht, Kristofer J., Mahony, Timothy J and Mitter, Neena (2021). Characterization of the biodistribution of a silica vesicle Nanovaccine carrying a Rhipicephalus (Boophilus) microplus protective antigen with in vivo live animal imaging. Frontiers in Bioengineering and Biotechnology, 8 606652, 1-11. doi: 10.3389/fbioe.2020.606652

Curcumin chemoprevention reduces the incidence of Braf mutant colorectal cancer in a preclinical study

Kane, Alexandra M., Liu, Cheng, Akhter, Dewan T., McKeone, Diane M., Bell, Craig A., Thurecht, Kristofer J., Leggett, Barbara A. and Whitehall, Vicki L. J. (2021). Curcumin chemoprevention reduces the incidence of Braf mutant colorectal cancer in a preclinical study. Digestive Diseases and Sciences, 66 (12), 4326-4332. doi: 10.1007/s10620-020-06752-y

Understanding the role of colon-specific microparticles based on retrograded starch/pectin in the delivery of chitosan nanoparticles along the gastrointestinal tract

dos Santos, Aline Martins, Meneguin, Andréia Bagliotti, Akhter, Dewan Taslima, Fletcher, Nicholas, Houston, Zachary H., Bell, Craig, Thurecht, Kristofer J. and Gremião, Maria Palmira Daflon (2021). Understanding the role of colon-specific microparticles based on retrograded starch/pectin in the delivery of chitosan nanoparticles along the gastrointestinal tract. European Journal of Pharmaceutics and Biopharmaceutics, 158, 371-378. doi: 10.1016/j.ejpb.2020.12.004

Engineering fluorescent gold nanoclusters using xanthate-functionalized hydrophilic polymers: toward enhanced monodispersity and stability

Deepagan, Veerasikku Gopal, Leiske, Meike N., Fletcher, Nicholas L., Rudd, David, Tieu, Terence, Kirkwood, Nicholas, Thurecht, Kristofer J., Kempe, Kristian, Voelcker, Nicolas H. and Cifuentes-Rius, Anna (2020). Engineering fluorescent gold nanoclusters using xanthate-functionalized hydrophilic polymers: toward enhanced monodispersity and stability. Nano Letters, 21 (1) acs.nanolett.0c03930, 476-484. doi: 10.1021/acs.nanolett.0c03930

A bispecific T cell engager targeting Glypican-1 redirects T cell cytolytic activity to kill prostate cancer cells

Lund, Maria E., Howard, Christopher B., Thurecht, Kristofer J., Campbell, Douglas H., Mahler, Stephen M. and Walsh, Bradley J. (2020). A bispecific T cell engager targeting Glypican-1 redirects T cell cytolytic activity to kill prostate cancer cells. BMC Cancer, 20 (1) 1214, 1214. doi: 10.1186/s12885-020-07562-1

The impact of polymer size and cleavability on the intravenous pharmacokinetics of PEG-based hyperbranched polymers in rats

Marasini, Nirmal, Fu, Changkui, Fletcher, Nicholas L., Subasic, Christopher, Er, Gerald, Mardon, Karine, Thurecht, Kristofer J., Whittaker, Andrew K. and Kaminskas, Lisa M. (2020). The impact of polymer size and cleavability on the intravenous pharmacokinetics of PEG-based hyperbranched polymers in rats. Nanomaterials, 10 (12) 2452, 1-16. doi: 10.3390/nano10122452

Effect of chain‐end chemistries on the efficiency of coupling antibodies to polymers using unnatural amino acids

Sivaram, Amal J., Wardiana, Andri, Preethi, S. S. Hema, Fuchs, Adrian V., Howard, Christopher B., Fletcher, Nicholas L., Bell, Craig A. and Thurecht, Kristofer J. (2020). Effect of chain‐end chemistries on the efficiency of coupling antibodies to polymers using unnatural amino acids. Macromolecular Rapid Communications, 41 (21) 2000294, e2000294. doi: 10.1002/marc.202000294

Nanobody-displaying porous silicon nanoparticles for the co-delivery of siRNA and doxorubicin

Tieu, Terence, Wojnilowicz, Marcin, Huda, Pie, Thurecht, Kristofer J., Thissen, Helmut, Voelcker, Nicolas H. and Cifuentes-Rius, Anna (2020). Nanobody-displaying porous silicon nanoparticles for the co-delivery of siRNA and doxorubicin. Biomaterials Science, 9 (1), 133-147. doi: 10.1039/d0bm01335h

Person-specific biomolecular coronas modulate nanoparticle interactions with immune cells in human blood

Ju, Yi, Kelly, Hannah G., Dagley, Laura F., Reynaldi, Arnold, Schlub, Timothy E., Spall, Sukhdeep K., Bell, Craig A., Cui, Jiwei, Mitchell, Andrew J., Lin, Zhixing, Wheatley, Adam K., Thurecht, Kristofer J., Davenport, Miles P., Webb, Andrew I., Caruso, Frank and Kent, Stephen J. (2020). Person-specific biomolecular coronas modulate nanoparticle interactions with immune cells in human blood. ACS Nano, 14 (11) acsnano.0c06679, 15723-15737. doi: 10.1021/acsnano.0c06679

Controlling the biological fate of micellar nanoparticles: balancing stealth and targeting

Sivaram, Amal J., Wardiana, Andri, Alcantara, Sheilajen, Sonderegger, Stefan E., Fletcher, Nicholas L., Houston, Zachary H., Howard, Christopher B., Mahler, Stephen M., Alexander, Cameron, Kent, Stephen J., Bell, Craig A. and Thurecht, Kristofer J. (2020). Controlling the biological fate of micellar nanoparticles: balancing stealth and targeting. ACS Nano, 14 (10) acsnano.0c06033, 13739-13753. doi: 10.1021/acsnano.0c06033

The Evolving Landscape of Polymer Science and Engineering in Australia

Kempe, Kristian and Thurecht, Kristofer J. (2020). The Evolving Landscape of Polymer Science and Engineering in Australia. Macromolecular Rapid Communications, 41 (18) 2000414, 1-2. doi: 10.1002/marc.202000414

Stepwise like supramolecular polymerization of plasmonic nanoparticle building blocks through complementary interactions

Dey, Priyanka, Thurecht, Kristofer J., Fredericks, Peter M. and Blakey, Idriss (2020). Stepwise like supramolecular polymerization of plasmonic nanoparticle building blocks through complementary interactions. Macromolecules, 53 (17) acs.macromol.0c01149, 7469-7478. doi: 10.1021/acs.macromol.0c01149

Next‐generation polymeric nanomedicines for oncology: perspectives and future directions

Fletcher, Nicholas L., Kempe, Kristian and Thurecht, Kristofer J. (2020). Next‐generation polymeric nanomedicines for oncology: perspectives and future directions. Macromolecular Rapid Communications, 41 (18) 2000319, 2000319. doi: 10.1002/marc.202000319

Hyperbranched Poly(2-oxazoline)s and Poly(ethylene glycol): A structure–activity comparison of biodistribution

Humphries, James, Pizzi, David, Sonderegger, Stefan E., Fletcher, Nicholas L., Houston, Zachary H., Bell, Craig A., Kempe, Kristian and Thurecht, Kristofer J. (2020). Hyperbranched Poly(2-oxazoline)s and Poly(ethylene glycol): A structure–activity comparison of biodistribution. Biomacromolecules, 21 (8) acs.biomac.0c00765, 3318-3331. doi: 10.1021/acs.biomac.0c00765

Surface polymer imprinted optical fibre sensor for dose detection of dabrafenib

He, Chenyang, Ledezma, Ulises Hernandez, Gurnani, Pratik, Albelha, Thais, Thurecht, Kristofer J., Correia, Ricardo, Morgan, Stephen P., Patel, Poulam, Alexander, Cameron and Korposh, Sergiy (2020). Surface polymer imprinted optical fibre sensor for dose detection of dabrafenib. Analyst, 145 (13), 4504-4511. doi: 10.1039/d0an00434k

Direct comparison of poly(ethylene glycol) and phosphorylcholine drug-loaded nanoparticles in vitro and in vivo

Noy, Janina-Miriam, Chen, Fan, Akhter, Dewan T., Houston, Zachary H., Fletcher, Nicholas L., Thurecht, Kristofer J. and Stenzel, Martina H. (2020). Direct comparison of poly(ethylene glycol) and phosphorylcholine drug-loaded nanoparticles in vitro and in vivo. Biomacromolecules, 21 (6) acs.biomac.0c00257, 2320-2333. doi: 10.1021/acs.biomac.0c00257

Synthesis of biscarboxylic acid functionalised EDTA mimicking polymers and their ability to form Zr(iv) chelation mediated nanostructures

Leiske, Meike N., Walker, Julia A., Zia, Aadarash, Fletcher, Nicholas L., Thurecht, Kristofer J., Davis, Thomas P. and Kempe, Kristian (2020). Synthesis of biscarboxylic acid functionalised EDTA mimicking polymers and their ability to form Zr(iv) chelation mediated nanostructures. Polymer Chemistry, 11 (16), 2799-2810. doi: 10.1039/d0py00304b

Understanding the uptake of nanomedicines at different stages of brain cancer using a modular nanocarrier platform and precision bispecific antibodies

Houston, Zachary H., Bunt, Jens, Chen, Kok-Siong, Puttick, Simon, Howard, Christopher B., Fletcher, Nicholas L., Fuchs, Adrian V., Cui, Jiwei, Ju, Yi, Cowin, Gary, Song, Xin, Boyd, Andrew W., Mahler, Stephen M., Richards, Linda J., Caruso, Frank and Thurecht, Kristofer J. (2020). Understanding the uptake of nanomedicines at different stages of brain cancer using a modular nanocarrier platform and precision bispecific antibodies. ACS Central Science, 6 (5) acscentsci.9b01299, 727-738. doi: 10.1021/acscentsci.9b01299

Investigation of the therapeutic potential of a synergistic delivery system through dual controlled release of camptothecin-doxorubicin

Zhao, Yongmei, Fletcher, Nicholas L., Gemmell, Anna, Houston, Zachary H., Howard, Christopher B., Blakey, Idriss, Liu, Tianqing and Thurecht, Kristofer J. (2020). Investigation of the therapeutic potential of a synergistic delivery system through dual controlled release of camptothecin-doxorubicin. Advanced Therapeutics, 3 (6) 1900202, 1900202. doi: 10.1002/adtp.201900202

Oral delivery of multicompartment nanomedicines for colorectal cancer therapeutics: combining loco-regional delivery with cell-target specificity

Akhter, Dewan T., Simpson, Joshua D., Fletcher, Nicholas L., Houston, Zachary H., Fuchs, Adrian V., Bell, Craig A. and Thurecht, Kristofer J. (2020). Oral delivery of multicompartment nanomedicines for colorectal cancer therapeutics: combining loco-regional delivery with cell-target specificity. Advanced Therapeutics, 3 (2), 1900171. doi: 10.1002/adtp.201900171

Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery

Ediriweera, Gayathri R., Simpson, Joshua D., Fuchs, Adrian V., Venkatachalam, Taracad K., Van De Walle, Matthias, Howard, Christopher B., Mahler, Stephen M., Blinco, James P., Fletcher, Nicholas L., Houston, Zachary H., Bell, Craig A. and Thurecht, Kristofer J. (2020). Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery. Chemical Science, 11 (12), 3268-3280. doi: 10.1039/d0sc00078g

Targeted beta therapy of prostate cancer with 177Lu-labelled Miltuximab® antibody against glypican-1 (GPC-1)

Yeh, Mei-Chun, Tse, Brian W. C., Fletcher, Nicholas L., Houston, Zachary H., Lund, Maria, Volpert, Marianna, Stewart, Chelsea, Sokolowski, Kamil A., Jeet, Varinder, Thurecht, Kristofer J., Campbell, Douglas H., Walsh, Bradley J., Nelson, Colleen C. and Russell, Pamela J. (2020). Targeted beta therapy of prostate cancer with 177Lu-labelled Miltuximab® antibody against glypican-1 (GPC-1). EJNMMI Research, 10 (1) 46, 46. doi: 10.1186/s13550-020-00637-x

Poly(2-oxazoline) macromonomers as building blocks for functional and biocompatible polymer architectures

Pizzi, David, Humphries, James, Morrow, Joshua P., Fletcher, Nicholas L., Bell, Craig A., Thurecht, Kristofer J. and Kempe, Kristian (2019). Poly(2-oxazoline) macromonomers as building blocks for functional and biocompatible polymer architectures. European Polymer Journal, 121 109258, 109258. doi: 10.1016/j.eurpolymj.2019.109258

Supramolecular fluorine magnetic resonance spectroscopy probe polymer based on Passerini bifunctional monomer

Couturaud, Benoit, Houston, Zachary H., Cowin, Gary J., Prokeš, Ivan, Foster, Jeffrey C., Thurecht, Kristofer J. and O'Reilly, Rachel K. (2019). Supramolecular fluorine magnetic resonance spectroscopy probe polymer based on Passerini bifunctional monomer. ACS Macro Letters, 8 (11), 1479-1483. doi: 10.1021/acsmacrolett.9b00626

Engineered polymeric materials for biological applications: overcoming challenges of the bio–nano interface

Simpson, Joshua D., Smith, Samuel A., Thurecht, Kristofer J. and Such, Georgina (2019). Engineered polymeric materials for biological applications: overcoming challenges of the bio–nano interface. Polymers, 11 (9) 1441, 1441. doi: 10.3390/polym11091441

Multifunctional lipid-coated calcium phosphate nanoplatforms for complete inhibition of large triple negative breast cancer via targeted combined therapy

Tang, Jie, Li, Bei, Howard, Christopher B., Mahler, Stephen M., Thurecht, Kristofer J., Wu, Yilun, Huang, Leaf and Xu, Zhi Ping (2019). Multifunctional lipid-coated calcium phosphate nanoplatforms for complete inhibition of large triple negative breast cancer via targeted combined therapy. Biomaterials, 216 119232, 119232. doi: 10.1016/j.biomaterials.2019.119232

Polymer design and component selection contribute to uptake, distribution & trafficking behaviours of polyethylene glycol hyperbranched polymers in live MDA-MB-468 breast cancer cells

Simpson, Joshua D., Ediriweera, Gayathri R., Howard, Christopher B., Fletcher, Nicholas L., Bell, Craig A. and Thurecht, Kristofer J. (2019). Polymer design and component selection contribute to uptake, distribution & trafficking behaviours of polyethylene glycol hyperbranched polymers in live MDA-MB-468 breast cancer cells. Biomaterials Science, 7 (11), 4661-4674. doi: 10.1039/c9bm00957d

Cellular targeting of bispecific antibody-functionalized poly(ethylene glycol) capsules: do shape and size matter?

Song, Danzi, Cui, Jiwei, Ju, Yi, Faria, Matthew, Sun, Huanli, Howard, Christopher B., Thurecht, Kristofer J. and Caruso, Frank (2019). Cellular targeting of bispecific antibody-functionalized poly(ethylene glycol) capsules: do shape and size matter?. ACS Applied Materials & Interfaces, 11 (32), 28720-28731. doi: 10.1021/acsami.9b10304

Tagged Core-Satellite Nanoassemblies: Role of Assembling Sequence on Surface-Enhanced Raman Scattering (SERS) Performance

Dey, Priyanka, Thurecht, Kristofer J., Fredericks, Peter M. and Blakey, Idriss (2019). Tagged Core-Satellite Nanoassemblies: Role of Assembling Sequence on Surface-Enhanced Raman Scattering (SERS) Performance. Applied Spectroscopy, 73 (12), 000370281985666-1435. doi: 10.1177/0003702819856666

Dispersibility of phospholipids and their optimization for the efficient production of liposomes using supercritical fluid technology

Maqbool, Faheem, Moyle, Peter M., Thurecht, Kristofer J. and Falconer, James R. (2019). Dispersibility of phospholipids and their optimization for the efficient production of liposomes using supercritical fluid technology. International Journal of Pharmaceutics, 563, 174-183. doi: 10.1016/j.ijpharm.2019.03.053

Innovative therapeutic strategies for effective treatment of brain metastases

Lim, Malcolm, Puttick, Simon, Houston, Zachary H., Thurecht, Kristofer J., Kalita-de Croft, Priyakshi, Mahler, Stephen, Rose, Stephen E., Jeffree, Rosalind L., Mazzieri, Roberta, Dolcetti, Riccardo, Lakhani, Sunil R. and Saunus, Jodi M. (2019). Innovative therapeutic strategies for effective treatment of brain metastases. International Journal of Molecular Sciences, 20 (6) 1280. doi: 10.3390/ijms20061280

Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies

Cui, Jiwei, Ju, Yi, Houston, Zachary H., Glass, Joshua J., Fletcher, Nicholas L., Alcantara, Sheilajen, Dai, Qiong, Howard, Christopher B., Mahler, Stephen M., Wheatley, Adam K., De Rose, Robert, Brannon, Paul T., Paterson, Brett M., Donnelly, Paul S., Thurecht, Kristofer J., Caruso, Frank and Kent, Stephen J. (2019). Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies. Advanced Healthcare Materials, 8 (9) 1801607, e1801607. doi: 10.1002/adhm.201801607

Ultrasound-responsive nanobubbles for enhanced intravitreal drug migration: An ex vivo evaluation

Thakur, Sachin S., Chen, Ying-Shan, Houston, Zachary H., Fletcher, Nicholas, Barnett, Nigel L., Thurecht, Kristofer J., Rupenthal, Ilva D. and Parekh, Harendra S. (2019). Ultrasound-responsive nanobubbles for enhanced intravitreal drug migration: An ex vivo evaluation. European Journal of Pharmaceutics and Biopharmaceutics, 136, 102-107. doi: 10.1016/j.ejpb.2019.01.014

Factorial design-assisted supercritical carbon-dioxide extraction of cytotoxic active principles from Carica papaya leaf juice

Khaw, Kooi-Yeong, Parat, Marie-Odile, Shaw, Paul Nicholas, Nguyen, Thao T. T., Pandey, Saurabh, Thurecht, Kristofer J. and Falconer, James Robert (2019). Factorial design-assisted supercritical carbon-dioxide extraction of cytotoxic active principles from Carica papaya leaf juice. Scientific Reports, 9 (1) 1716, 1716. doi: 10.1038/s41598-018-37171-9

Preparation of albendazole-loaded liposomes by supercritical carbon dioxide processing

Maqbool, Faheem, Moyle, Peter M., Tan, Madeleine S. A., Thurecht, Kristofer J. and Falconer, James R. (2019). Preparation of albendazole-loaded liposomes by supercritical carbon dioxide processing. Artificial Cells, Nanomedicine, and Biotechnology, 46 (sup3), 1-7. doi: 10.1080/21691401.2018.1536059

Importance of polymer length in fructose-based polymeric micelles for an enhanced biological activity

Lu, Mingxia, Chen, Fan, Cao, Cheng, Garvey, Christopher J., Fletcher, Nicholas L., Houston, Zachary H., Lu, Hongxu, Lord, Megan S., Thurecht, Kristofer J. and Stenzel, Martina H. (2019). Importance of polymer length in fructose-based polymeric micelles for an enhanced biological activity. Macromolecules, 52 (2) acs.macromol.8b02381, 477-486. doi: 10.1021/acs.macromol.8b02381

RNA interference to enhance radiation therapy: targeting the DNA damage response

Ratnayake, G., Bain, A. L., Fletcher, N., Howard, C. B., Khanna, K. K. and Thurecht, K. J. (2018). RNA interference to enhance radiation therapy: targeting the DNA damage response. Cancer Letters, 439, 14-23. doi: 10.1016/j.canlet.2018.09.011

EphA3 pay-loaded antibody therapeutics for the treatment of glioblastoma

Offenhäuser, Carolin, Al-Ejeh, Fares, Puttick, Simon, Ensbey, Kathleen, Bruce, Zara, Jamieson, Paul, Smith, Fiona, Stringer, Brett, Carrington, Benjamin, Fuchs, Adrian, Bell, Craig, Jeffree, Rosalind, Rose, Stephen, Thurecht, Kristofer, Boyd, Andrew and Day, Bryan (2018). EphA3 pay-loaded antibody therapeutics for the treatment of glioblastoma. Cancers, 10 (12) 519, 519. doi: 10.3390/cancers10120519

Dependence of block copolymer domain spacing and morphology on the cation structure of ionic liquid additives

Bennett, Thomas M., Chambers, Lewis C., Thurecht, Kristofer J., Jack, Kevin S. and Blakey, Idriss (2018). Dependence of block copolymer domain spacing and morphology on the cation structure of ionic liquid additives. Macromolecules, 51 (21) acs.macromol.8b01953, 8979-8986. doi: 10.1021/acs.macromol.8b01953

Minimum information reporting in bio–nano experimental literature

Faria, Matthew, Björnmalm, Mattias, Thurecht, Kristofer J., Kent, Stephen J., Parton, Robert G., Kavallaris, Maria, Johnston, Angus P. R., Gooding, J. Justin, Corrie, Simon R., Boyd, Ben J., Thordarson, Pall, Whittaker, Andrew K., Stevens, Molly M., Prestidge, Clive A., Porter, Christopher J. H., Parak, Wolfgang J., Davis, Thomas P., Crampin, Edmund J. and Caruso, Frank (2018). Minimum information reporting in bio–nano experimental literature. Nature Nanotechnology, 13 (9), 777-785. doi: 10.1038/s41565-018-0246-4

Influence of Charge on Hemocompatibility and Immunoreactivity of Polymeric Nanoparticles

Chen, Liyu, Glass, Joshua J., De Rose, Robert, Sperling, Claudia, Kent, Stephen J., Houston, Zachary H., Fletcher, Nicholas L., Rolfe, Barbara E. and Thurecht, Kristofer J. (2018). Influence of Charge on Hemocompatibility and Immunoreactivity of Polymeric Nanoparticles. ACS Applied Bio Materials, 1 (3) acsabm.8b00220, 756-767. doi: 10.1021/acsabm.8b00220

In vivo therapeutic evaluation of polymeric nanomedicines: effect of different targeting peptides on therapeutic efficacy against breast cancer

Zhao, Yongmei, Fletcher, Nicholas L., Liu, Tianqing, Gemmell, Anna C., Houston, Zachary H., Blakey, Idriss and Thurecht, Kristofer J. (2018). In vivo therapeutic evaluation of polymeric nanomedicines: effect of different targeting peptides on therapeutic efficacy against breast cancer. Nanotheranostics, 2 (4), 360-370. doi: 10.7150/ntno.27142

Confinement of therapeutic enzymes in selectively permeable polymer vesicles by Polymerization-Induced Self-Assembly (PISA) reduces antibody binding and proteolytic susceptibility

Blackman, Lewis D., Varlas, Spyridon, Arno, Maria C., Houston, Zachary H., Fletcher, Nicholas L., Thurecht, Kristofer J., Hasan, Muhammad, Gibson, Matthew I. and O’Reilly, Rachel K. (2018). Confinement of therapeutic enzymes in selectively permeable polymer vesicles by Polymerization-Induced Self-Assembly (PISA) reduces antibody binding and proteolytic susceptibility. ACS Central Science, 4 (6), 718-723. doi: 10.1021/acscentsci.8b00168

Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: challenges and opportunities

Belfiore, Lisa, Saunders, Darren N., Ranson, Marie, Thurecht, Kristofer J., Storm, Gert and Vine, Kara L. (2018). Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: challenges and opportunities. Journal of Controlled Release, 277, 1-13. doi: 10.1016/j.jconrel.2018.02.040

Modified organosilica core-shell nanoparticles for stable pH sensing in biological solutions

Robinson, Kye J., Huynh, Gabriel T., Kouskousis, Betty P., Fletcher, Nicholas L., Houston, Zachary H., Thurecht, Kristofer J. and Corrie, Simon R. (2018). Modified organosilica core-shell nanoparticles for stable pH sensing in biological solutions. ACS Sensors, 3 (5), 967-975. doi: 10.1021/acssensors.8b00034

Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands

Tang, Jie, Howard, Christopher B., Mahler, Stephen M., Thurecht, Kristofer J., Huang, Leaf and Xu, Zhi Ping (2018). Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands. Nanoscale, 10 (9), 4258-4266. doi: 10.1039/c7nr08644j

Bispecific antibody-functionalized upconversion nanoprobe

He, Hao, Howard, Christopher B., Chen, Yinghui, Wen, Shihui, Lin, Gungun, Zhou, Jiajia, Thurecht, Kristofer J. and Jin, Dayong (2018). Bispecific antibody-functionalized upconversion nanoprobe. Analytical Chemistry, 90 (5), 3024-3029. doi: 10.1021/acs.analchem.7b05341

Designed multifunctional polymeric nanomedicines: long-term biodistribution and tumour accumulation of aptamer-targeted nanomaterials

Fletcher, N. L., Houston, Z. H., Simpson, J. D., Veedu, R. N. and Thurecht, K. J. (2018). Designed multifunctional polymeric nanomedicines: long-term biodistribution and tumour accumulation of aptamer-targeted nanomaterials. Chemical Communications, 54 (82), 11538-11541. doi: 10.1039/c8cc05831h

Recent advances in the generation of antibody-nanomaterial conjugates

Sivaram, Amal J, Wardiana, Andri, Howard, Christopher B, Mahler, Stephen M and Thurecht, Kristofer J (2018). Recent advances in the generation of antibody-nanomaterial conjugates. Advanced Healthcare Materials, 7 (1) 1700607. doi: 10.1002/adhm.201700607

Effects of Surface Charge of Hyperbranched Polymers on Cytotoxicity, Dynamic Cellular Uptake and Localization, Hemotoxicity, and Pharmacokinetics in Mice

Chen, Liyu, Simpson, Joshua D, Fuchs, Adrian V, Rolfe, Barbara E and Thurecht, Kristofer J (2017). Effects of Surface Charge of Hyperbranched Polymers on Cytotoxicity, Dynamic Cellular Uptake and Localization, Hemotoxicity, and Pharmacokinetics in Mice. Molecular pharmaceutics, 14 (12), 4485-4497. doi: 10.1021/acs.molpharmaceut.7b00611

Gold Nanocluster-Mediated Cellular Death under Electromagnetic Radiation

Cifuentes-Rius, Anna, Ivask, Angela, Das, Shreya, Penya-Auladell, Nuria, Fabregas, Laura, Fletcher, Nicholas L., Houston, Zachary H., Thurecht, Kristofer J. and Voelcker, Nicolas H. (2017). Gold Nanocluster-Mediated Cellular Death under Electromagnetic Radiation. Acs Applied Materials & Interfaces, 9 (47), 41159-41167. doi: 10.1021/acsami.7b13100

Localised delivery of doxorubicin to prostate cancer cells through a PSMA-targeted hyperbranched polymer theranostic

Pearce, Amanda K., Simpson, Joshua D., Fletcher, Nicholas L., Houston, Zachary H., Fuchs, Adrian V., Russell, Pamela J., Whittaker, Andrew K. and Thurecht, Kristofer J. (2017). Localised delivery of doxorubicin to prostate cancer cells through a PSMA-targeted hyperbranched polymer theranostic. Biomaterials, 141, 330-339. doi: 10.1016/j.biomaterials.2017.07.004

Bridging Bio-Nano Science and Cancer Nanomedicine

Björnmalm, Mattias, Thurecht, Kristofer J., Michael, Michael, Scott, Andrew M. and Caruso, Frank (2017). Bridging Bio-Nano Science and Cancer Nanomedicine. Acs Nano, 11 (10), 9594-9613. doi: 10.1021/acsnano.7b04855

Using peptide aptamer targeted polymers as a model nanomedicine for investigating drug distribution in cancer nanotheranostics

Zhao, Yongmei, Houston, Zachary H., Simpson, Joshua D., Chen, Liyu, Fletcher, Nicholas L., Fuchs, Adrian V., Blakey, Idriss and Thurecht, Kristofer J. (2017). Using peptide aptamer targeted polymers as a model nanomedicine for investigating drug distribution in cancer nanotheranostics. Molecular Pharmaceutics, 14 (10), 3539-3549. doi: 10.1021/acs.molpharmaceut.7b00560

Switchable 19F MRI polymer theranostics: towards in situ quantifiable drug release

Fuchs, A. V., Bapat, A. P., Cowin, G. J. and Thurecht, K. J. (2017). Switchable 19F MRI polymer theranostics: towards in situ quantifiable drug release. Polymer Chemistry, 8 (34), 5157-5166. doi: 10.1039/c7py00345e

Charge has a marked influence on hyperbranched polymer nanoparticle association in whole human blood

Glass, Joshua J., Chen, Liyu, Alcantara, Sheilajen, Crampin, Edmund J., Thurecht, Kristofer J., De Rose, Robert and Kent, Stephen J. (2017). Charge has a marked influence on hyperbranched polymer nanoparticle association in whole human blood. ACS Macro Letters, 6 (6), 586-592. doi: 10.1021/acsmacrolett.7b00229

Synthesis and post-polymerisation ligations of PEG-based hyperbranched polymers for RNA conjugation via reversible disulfide linkage

Ardana, Aditya, Whittaker, Andrew K. and Thurecht, Kristofer J. (2017). Synthesis and post-polymerisation ligations of PEG-based hyperbranched polymers for RNA conjugation via reversible disulfide linkage. Macromolecular Research, 25 (6), 599-614. doi: 10.1007/s13233-017-5111-z

In vivo fate of carbon nanotubes with different physicochemical properties for gene delivery applications

Cifuentes-Rius, Anna, Boase, Nathan R. B., Font, Ines, Coronas, Nuria, Ramos-Perez, Victor, Thurecht, Kristofer J. and Borros, Salvador (2017). In vivo fate of carbon nanotubes with different physicochemical properties for gene delivery applications. ACS Applied Materials and Interfaces, 9 (13), 11461-11471. doi: 10.1021/acsami.7b00677

Stability of trithiocarbonate RAFT agents containing both a cyano and a carboxylic acid functional group

Fuchs, Adrian V. and Thurecht, Kristofer J. (2017). Stability of trithiocarbonate RAFT agents containing both a cyano and a carboxylic acid functional group. ACS Macro Letters, 6 (3), 287-291. doi: 10.1021/acsmacrolett.7b00100

Nano-bio interactions: guiding the development of nanoparticle therapeutics, diagnostics, and imaging agents

Corrie, Simon R. and Thurecht, Kristofer J. (2016). Nano-bio interactions: guiding the development of nanoparticle therapeutics, diagnostics, and imaging agents. Pharmaceutical Research, 33 (10), 2311-2313. doi: 10.1007/s11095-016-2009-y

Nanoparticle-based medicines: a review of FDA-approved materials and clinical trials to date

Bobo, Daniel, Robinson, Kye J., Islam, Jiaul, Thurecht, Kristofer J. and Corrie, Simon R. (2016). Nanoparticle-based medicines: a review of FDA-approved materials and clinical trials to date. Pharmaceutical Research, 33 (10), 2373-2387. doi: 10.1007/s11095-016-1958-5

Preclinical imaging of siRNA delivery

Fletcher, Nicholas, Ardana, Aditya and Thurecht, Kristofer J. (2016). Preclinical imaging of siRNA delivery. Australian Journal of Chemistry, 69 (10), 1073-1077. doi: 10.1071/CH16079

Targeted nanomaterials: overcoming instability of antibody-nanomaterial conjugates: next generation targeted nanomedicines using bispecific antibodies (Adv. Healthcare Mater. 16/2016)

Howard, Christopher B., Fletcher, Nicholas, Houston, Zachary H., Fuchs, Adrian V., Boase, Nathan R. B., Simpson, Joshua D., Raftery, Lyndon J., Ruder, Tim, Jones, Martina L., de Bakker, Christopher J., Mahler, Stephen M. and Thurecht, Kristofer J. (2016). Targeted nanomaterials: overcoming instability of antibody-nanomaterial conjugates: next generation targeted nanomedicines using bispecific antibodies (Adv. Healthcare Mater. 16/2016). Advanced Healthcare Materials, 5 (16), 1994-1994. doi: 10.1002/adhm.201670084

Bioerodable PLGA-based microparticles for producing sustained-release drug formulations and strategies for improving drug loading

Han, Felicity Y., Thurecht, Kristofer J., Whittaker, Andrew K. and Smith, Maree T. (2016). Bioerodable PLGA-based microparticles for producing sustained-release drug formulations and strategies for improving drug loading. Frontiers in Pharmacology, 7 (JUN) 185, 1-11. doi: 10.3389/fphar.2016.00185

Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies

Howard, Christopher B., Fletcher, Nicholas, Houston, Zachary H., Fuchs, Adrian V., Boase, Nathan R. B., Simpson, Joshua D., Raftery, Lyndon J., Ruder, Tim, Jones, Martina L., de Bakker, Christopher J., Mahler, Stephen M. and Thurecht, Kristofer J. (2016). Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies. Advanced Healthcare Materials, 5 (16), 2055-2068. doi: 10.1002/adhm.201600263

Targeting Nanomedicines to Prostate Cancer: Evaluation of Specificity of Ligands to Two Different Receptors In Vivo

Pearce, Amanda K., Fuchs, Adrian V., Fletcher, Nicholas L. and Thurecht, Kristofer J. (2016). Targeting Nanomedicines to Prostate Cancer: Evaluation of Specificity of Ligands to Two Different Receptors In Vivo. Pharmaceutical Research, 33 (10), 1-12. doi: 10.1007/s11095-016-1945-x

Fluorinated POSS-star polymers for 19F MRI

Wang, Kewei, Peng, Hui, Thurecht, Kristofer J. and Whittaker, Andrew K. (2016). Fluorinated POSS-star polymers for 19F MRI. Macromolecular Chemistry and Physics, 217 (20), 2262-2274. doi: 10.1002/macp.201600084

Biosensing made easy with PEG-targeted bi-specific antibodies

Raftery, Lyndon J., Grewal, Yadveer S., Howard, Christopher B., Jones, Martina L., Shiddiky, Muhammad J. A., Carrascosa, Laura G., Thurecht, Kristofer J., Mahler, Stephen M. and Trau, Matt (2016). Biosensing made easy with PEG-targeted bi-specific antibodies. Chemical Communications, 52 (33), 5730-5733. doi: 10.1039/C6CC01916A

Synthesis, characterization and biological activities of semicarbazones and their copper complexes

Venkatachalam, Taracad K., Bernhardt, Paul V., Noble, Chris J., Fletcher, Nicholas, Pierens, Gregory K., Thurecht, Kris J. and Reutens, David C. (2016). Synthesis, characterization and biological activities of semicarbazones and their copper complexes. Journal of Inorganic Biochemistry, 162, 295-308. doi: 10.1016/j.jinorgbio.2016.04.006

Synthesis of 19F nucleic acid-polymer conjugates as real-time MRI probes of biorecognition

Sicilia, Giovanna, Davis, Adrienne L., Spain, Sebastian G., Magnusson, Johannes P., Boase, Nathan R. B., Thurecht, Kristofer J. and Alexander, Cameron (2016). Synthesis of 19F nucleic acid-polymer conjugates as real-time MRI probes of biorecognition. Polymer Chemistry, 7 (12), 2180-2191. doi: 10.1039/c5py01883h

Perturbation of the experimental phase diagram of a diblock copolymer by blending with an ionic liquid

Bennett, Thomas M., Jack, Kevin S., Thurecht, Kristofer J. and Blakey, Idriss (2016). Perturbation of the experimental phase diagram of a diblock copolymer by blending with an ionic liquid. Macromolecules, 49 (1), 205-214. doi: 10.1021/acs.macromol.5b02041

Multifunctional hyperbranched polymers for CT/19F MRI bimodal molecular imaging

Wang, Kewei, Peng, Hui, Thurecht, Kristofer J., Puttick, Simon and Whittaker, Andrew K. (2016). Multifunctional hyperbranched polymers for CT/19F MRI bimodal molecular imaging. Polymer Chemistry, 7 (5), 1059-1069. doi: 10.1039/c5py01707f

Spectral normalisation by error minimisation for prediction of conversion in solvent-free catalytic chain transfer polymerisations

Richardson, Samuel J., Blakey, Idriss, Thurecht, Kristofer J., Irvine, Derek J. and Whittaker, Andrew K. (2016). Spectral normalisation by error minimisation for prediction of conversion in solvent-free catalytic chain transfer polymerisations. RSC Advances, 6 (73), 69484-69491. doi: 10.1039/c6ra06462k

Comparison between polyethylene glycol and zwitterionic polymers as antifouling coatings on wearable devices for selective antigen capture from biological tissue

Robinson, Kye J., Coffey, Jacob W., Muller, David A., Young, Paul R., Kendall, Mark A., Thurecht, Kristofer J., Grøndahl, Lisbeth and Corrie, Simon R. (2015). Comparison between polyethylene glycol and zwitterionic polymers as antifouling coatings on wearable devices for selective antigen capture from biological tissue. Biointerphases, 10 (4) 04A305, 04A305.1-04A305.11. doi: 10.1116/1.4932055

Evaluation of polymeric nanomedicines targeted to PSMA: effect of ligand on targeting efficiency

Fuchs, Adrian V., Tse, Brian W.C., Pearce, Amanda. K., Yeh, Mei-Chun, Fletcher, Nicholas L., Huang, Steve S., Heston, Warren D., Whittaker, Andrew K., Russell, Pamela J. and Thurecht, Kristofer J. (2015). Evaluation of polymeric nanomedicines targeted to PSMA: effect of ligand on targeting efficiency. Biomacromolecules, 16 (10), 3235-3247. doi: 10.1021/acs.biomac.5b00913

The in vivo fate of nanoparticles and nanoparticle-loaded microcapsules after oral administration in mice: evaluation of their potential for colon-specific delivery

Ma, Yiming, Fuchs, Adrian V., Boase, Nathan R. B., Rolfe, Barbara E., Coombes, Allan G. A. and Thurecht, Kristofer J. (2015). The in vivo fate of nanoparticles and nanoparticle-loaded microcapsules after oral administration in mice: evaluation of their potential for colon-specific delivery. European Journal of Pharmaceutics and Biopharmaceutics, 94, 393-403. doi: 10.1016/j.ejpb.2015.06.014

Segmented Highly Branched Copolymers: Rationally Designed Macromolecules for Improved and Tunable 19F MRI

Wang, Kewei, Peng, Hui, Thurecht, Kristofer J., Puttick, Simon and Whittaker, Andrew K. (2015). Segmented Highly Branched Copolymers: Rationally Designed Macromolecules for Improved and Tunable 19F MRI. Biomacromolecules, 16 (9), 2827-2839. doi: 10.1021/acs.biomac.5b00800

EphA2 as a Diagnostic Imaging Target in Glioblastoma: A Positron Emission Tomography/Magnetic Resonance Imaging Study

Puttick, Simon, Stringer, Brett W., Day, Bryan W., Bruce, Zara C., Ensbey, Kathleen S., Mardon, Karine, Cowin, Gary J., Thurecht, Kristofer J, Whittaker, Andrew K., Fay, Michael, Boyd, Andrew W. and Rose, Stephen (2015). EphA2 as a Diagnostic Imaging Target in Glioblastoma: A Positron Emission Tomography/Magnetic Resonance Imaging Study. Molecular Imaging, 14 (6), 385-395. doi: 10.2310/7290.2015.00008

Novel polymeric bioerodable microparticles for prolonged-release intrathecal delivery of analgesic agents for relief of intractable cancer-related pain

Han, Felicity Y., Thurecht, Kristofer J., Lam, Ai-Leen, Whittaker, Andrew K. and Smith, Maree T. (2015). Novel polymeric bioerodable microparticles for prolonged-release intrathecal delivery of analgesic agents for relief of intractable cancer-related pain. Journal of Pharmaceutical Sciences, 104 (7), 2334-2344. doi: 10.1002/jps.24497

Interfacial RAFT Miniemulsion Polymerization: Architectures from an Interface

Fuchs, Adrian V. and Thurecht, Kristofer J. (2015). Interfacial RAFT Miniemulsion Polymerization: Architectures from an Interface. Macromolecular Chemistry And Physics, 216 (12), 1271-1281. doi: 10.1002/macp.201500061

Utilising polymers to understand diseases: advanced molecular imaging agents

Fuchs, Adrian V., Gemmell, Anna C. and Thurecht, Kristofer J. (2015). Utilising polymers to understand diseases: advanced molecular imaging agents. Polymer Chemistry, 2015 (6), 868-880. doi: 10.1039/c4py01311e

In vivo evaluation of folate decorated cross-linked micelles for the delivery of platinum anticancer drugs

Eliezar, Jeaniffer, Scarano, Wei, Boase, Nathan R. B., Thurecht, Kristofer J. and Stenzel, Martina H. (2015). In vivo evaluation of folate decorated cross-linked micelles for the delivery of platinum anticancer drugs. Biomacromolecules, 16 (2), 515-523. doi: 10.1021/bm501558d

Polymeric siRNA delivery vectors: knocking down cancers with polymeric‐based gene delivery systems

Ardana, Aditya, Whittaker, Andrew, McMillan, Nigel A. J. and Thurecht, Kristofer J. (2014). Polymeric siRNA delivery vectors: knocking down cancers with polymeric‐based gene delivery systems. Journal of Chemical Technology and Biotechnology, 90 (7), 1196-1208. doi: 10.1002/jctb.4508

Development of a polymer theranostic for prostate cancer

Pearce, Amanda K., Rolfe, Barbara E., Russell, Pamela J., Tse, Brian W.-C., Whittaker, Andrew K., Fuchs, Adrian V. and Thurecht, Kristofer J. (2014). Development of a polymer theranostic for prostate cancer. Polymer Chemistry, 5 (24), 6932-6942. doi: 10.1039/C4PY00999A

Imaging tumour distribution of a polymeric drug delivery platform in vivo by PET-MRI

Puttick, Simon, Boase, Nathan R. B., Blakey, Idriss and Thurecht, Kristofer J. (2014). Imaging tumour distribution of a polymeric drug delivery platform in vivo by PET-MRI. Journal of Chemical Technology and Biotechnology, 90 (7), 1237-1244. doi: 10.1002/jctb.4489

PEG-based hyperbranched polymer theranostics: optimizing chemistries for improved bioconjugation

Ardana, Aditya, Whittaker, Andrew K. and Thurecht, Kristofer J. (2014). PEG-based hyperbranched polymer theranostics: optimizing chemistries for improved bioconjugation. Macromolecules, 47 (15), 5211-5219. doi: 10.1021/ma501196h

Self assembly of plasmonic core-satellite nano-assemblies mediated by hyperbranched polymer linkers

Dey, Priyanka, Zhu, Shaoli, Thurecht, Kristofer J., Fredericks, Peter M. and Blakey, Idriss (2014). Self assembly of plasmonic core-satellite nano-assemblies mediated by hyperbranched polymer linkers. Journal of Materials Chemistry B, 2 (19), 2827-2837. doi: 10.1039/c4tb00263f

Synthesis of a multimodal molecular imaging probe based on a hyperbranched polymer architecture

Boase, Nathan R. B., Blakey, Idriss, Rolfe, Barbara E., Mardon, Karine and Thurecht, Kristofer J. (2014). Synthesis of a multimodal molecular imaging probe based on a hyperbranched polymer architecture. Polymer Chemistry, 5 (15), 4450-4458. doi: 10.1039/c4py00513a

Biodegradable core crosslinked star polymer nanoparticles as 19F MRI contrast agents for selective imaging

Wang, Kewei, Peng, Hui, Thurecht, Kristofer J., Puttick, Simon and Whittaker, Andrew K. (2014). Biodegradable core crosslinked star polymer nanoparticles as 19F MRI contrast agents for selective imaging. Polymer Chemistry, 5 (5), 1760-1771. doi: 10.1039/c3py01311a

Hyperbranched polymer-gold nanoparticle assemblies: role of polymer architecture in hybrid assembly formation and SERS activity

Dey, Priyanka, Blakey, Idriss, Thurecht, Kristofer J. and Fredericks, Peter M. (2014). Hyperbranched polymer-gold nanoparticle assemblies: role of polymer architecture in hybrid assembly formation and SERS activity. Langmuir, 30 (8), 2249-2258. doi: 10.1021/la4047462

Multimodal polymer nanoparticles with combined 19F magnetic resonance and optical detection for tunable, targeted, multimodal imaging in vivo

Rolfe, Barbara E., Blakey, Idriss, Squires, Oliver, Peng, Hui, Boase, Nathan R. B., Alexander, Cameron, Parsons, Peter G., Boyle, Glen M., Whittaker, Andrew K. and Thurecht, Kristofer J. (2014). Multimodal polymer nanoparticles with combined 19F magnetic resonance and optical detection for tunable, targeted, multimodal imaging in vivo. Journal of the American Chemical Society, 136 (6), 2413-2419. doi: 10.1021/ja410351h

A comparative study: The impact of different lipid extraction methods on current microalgal lipid research

Li, Yan, Ghasemi Naghdi, Forough, Garg, Sourabh, Adarme-Vega, Tania Catalina, Thurecht, Kristofer J., Ghafor, Wael Abdul, Tannock, Simon and Schenk, Peer M. (2014). A comparative study: The impact of different lipid extraction methods on current microalgal lipid research. Microbial Cell Factories, 13 (1) 14, 14. doi: 10.1186/1475-2859-13-14

Can ionic liquid additives be used to extend the scope of poly(styrene)-block-poly(methyl methacrylate) for directed self-assembly?

Bennett, Thomas M., Pei, Kevin, Cheng, Han-Hao, Thurecht, Kristofer J., Jack, Kevin S. and Blakey, Idriss (2014). Can ionic liquid additives be used to extend the scope of poly(styrene)-block-poly(methyl methacrylate) for directed self-assembly?. Journal of Micro/Nanolithography, MEMS and MOEMS, 13 (3) 031304, 031304.1-031304.9. doi: 10.1117/1.JMM.13.3.031304

Effect of supercritical carbon dioxide on the loading and release of model drugs from polyurethane films: comparison with solvent casting

Zhang, Jing, Martin, Darren J., Taran, Elena, Thurecht, Kristofer J. and Minchin, Rodney F. (2014). Effect of supercritical carbon dioxide on the loading and release of model drugs from polyurethane films: comparison with solvent casting. Macromolecular Chemistry and Physics, 215 (1), 54-64. doi: 10.1002/macp.201300492

Facile one-spot synthesis of highly branched polycaprolactone

Nguyen, Nam T., Thurecht, Kristofer J., Howdle, Steve M. and Irvine, Derek J. (2014). Facile one-spot synthesis of highly branched polycaprolactone. Polymer Chemistry, 5 (8), 2997-3008. doi: 10.1039/c3py01725g

pH-responsive star polymer nanoparticles: potential F-19 MRI contrast agents for tumour-selective imaging

Wang, Kewei, Peng, Hui, Thurecht, Kristofer J., Puttick, Simon and Whittaker, Andrew K. (2013). pH-responsive star polymer nanoparticles: potential F-19 MRI contrast agents for tumour-selective imaging. Polymer Chemistry, 4 (16), 4480-4489. doi: 10.1039/c3py00654a

A method for controlling the aggregation of gold nanoparticles: Tuning of optical and spectroscopic properties

Blakey, Idriss, Merican, Zul and Thurecht, Kristofer J. (2013). A method for controlling the aggregation of gold nanoparticles: Tuning of optical and spectroscopic properties. Langmuir, 29 (26), 8266-8274. doi: 10.1021/la401361u

Influence of oxidation upon the CO2 capture performance of a phenolic-resin-derived carbon

Plaza, M. G., Thurecht, K. J., Pevida, C., Rubiera, F., Pis, J. J., Snape, C. E. and Drage, T. C. (2013). Influence of oxidation upon the CO2 capture performance of a phenolic-resin-derived carbon. Fuel Processing Technology, 110, 53-60. doi: 10.1016/j.fuproc.2013.01.011

Enhanced uptake of nanoparticle drug carriers via a thermoresponsive shell enhances cytotoxicity in a cancer cell line

Abulateefeh, Samer R., Spain, Sebastian G., Thurecht, Kristofer J., Aylott, Jonathan W., Chan, Weng C., Garnett, Martin C. and Alexander, Cameron (2013). Enhanced uptake of nanoparticle drug carriers via a thermoresponsive shell enhances cytotoxicity in a cancer cell line. Biomaterials Science, 1 (4), 434-442. doi: 10.1039/c2bm00184e

Self-assembled hyperbranched polymer-gold nanoparticle hybrids: understanding the effect of polymer coverage on assembly size and SERS performance

Dey, Priyanka, Blakey, Idriss, Thurecht, Kristofer J. and Fredericks, Peter M. (2013). Self-assembled hyperbranched polymer-gold nanoparticle hybrids: understanding the effect of polymer coverage on assembly size and SERS performance. Langmuir, 29 (2), 525-533. doi: 10.1021/la304034b

Aptamer-targeted hyperbranched polymers: towards greater specificity for tumours in vivo

Coles, Daniel J., Rolfe, Barbara E., Boase, Nathan R. B., Veedu, Rakesh N. and Thurecht, Kristofer J. (2013). Aptamer-targeted hyperbranched polymers: towards greater specificity for tumours in vivo. Chemical Communications, 49 (37), 3836-3838. doi: 10.1039/c3cc00127j

SERS-based detection of barcoded gold nanoparticle assemblies from within animal tissue

Dey, Priyanka, Olds, William, Blakey, Idriss, Thurecht, Kristofer J., Izake, Emad L. and Fredericks, Peter M. (2013). SERS-based detection of barcoded gold nanoparticle assemblies from within animal tissue. Journal of Raman Spectroscopy, 44 (12), 1659-1665. doi: 10.1002/jrs.4399

The influence of domain segregation in ionic liquids upon controlled polymerisation mechanisms: RAFT polymerisation

Puttick, Simon, Davis, Adrienne L., Butler, Kevin, Irvine, Derek J., Licence, Peter and Thurecht, Kristofer J. (2013). The influence of domain segregation in ionic liquids upon controlled polymerisation mechanisms: RAFT polymerisation. Polymer Chemistry, 4 (5), 1337-1344. doi: 10.1039/C2PY20835K

Polymers as probes for multimodal imaging with MRI

Thurecht, Kristofer J. (2012). Polymers as probes for multimodal imaging with MRI. Macromolecular Chemistry and Physics, 213 (24), 2567-2572. doi: 10.1002/macp.201200420

Effect of solvent quality on the solution properties of assemblies of partially fluorinated amphiphilic diblock copolymers

Peng, Hui, Thurecht, Kristofer J., Blakey, Idriss, Taran, Elena and Whittaker, Andrew K. (2012). Effect of solvent quality on the solution properties of assemblies of partially fluorinated amphiphilic diblock copolymers. Macromolecules, 45 (21), 8681-8690. doi: 10.1021/ma3019188

One-pot synthesis of block copolymers in supercritical carbon dioxide: A simple versatile route to nanostructured microparticles

Jennings, James, Beija, Mariana, Richez, Alexandre P., Cooper, Samuel D., Mignot, Paul E., Thurecht, Kristofer J., Jack, Kevin S. and Howdle, Steven M. (2012). One-pot synthesis of block copolymers in supercritical carbon dioxide: A simple versatile route to nanostructured microparticles. Journal of the American Chemical Society, 134 (10), 4772-4781. doi: 10.1021/ja210577h

Hyperbranched polymers for molecular imaging: Designing polymers for parahydrogen induced polarisation (PHIP)

Munnemann, Kerstin, Kolzer, Michael, Blakey, Idriss, Whittaker, Andrew K. and Thurecht, Kristofer J. (2012). Hyperbranched polymers for molecular imaging: Designing polymers for parahydrogen induced polarisation (PHIP). Chemical Communications, 48 (10), 1583-1585. doi: 10.1039/c1cc16077j

Hyperbranched polymers as delivery vectors for oligonucleotides

Tan, Jian Hong, McMillan, Nigel A. J., Payne, Elizabeth, Alexander, Cameron, Heath, Felicity, Whittaker, Andrew K. and Thurecht, Kristofer J. (2012). Hyperbranched polymers as delivery vectors for oligonucleotides. Journal of Polymer Science Part A: Polymer Chemistry, 50 (13), 2585-2595. doi: 10.1002/pola.26055

In situ formation of crosslinked core-corona polymeric nanoparticles from a novel hyperbranched core

Zheng, Yu, Thurecht, Kristofer J., Chen, Xinyong, Roberts, Clive J., Irvine, Derek J., Howdle, Steven M. and Wang, Wenxin (2012). In situ formation of crosslinked core-corona polymeric nanoparticles from a novel hyperbranched core. Polymer Chemistry, 3 (10), 2807-2814. doi: 10.1039/c2py20247f

Molecular imaging with polymers

Boase, Nathan R. B., Blakey, Idriss and Thurecht, Kristofer J. (2012). Molecular imaging with polymers. Polymer Chemistry, 3 (6), 1384-1389. doi: 10.1039/c2py20132a

New vinyl ester copolymers as stabilisers for dispersion polymerisation in scCO2

Park, Eun Ju, Richez, Alexandre P., Birkin, Natasha A., Lee, Hyunsuk, Arrowsmith, Nicholas, Thurecht, Kristofer J. and Howdle, Steven M. (2011). New vinyl ester copolymers as stabilisers for dispersion polymerisation in scCO2. Polymer, 52 (24), 5403-5409. doi: 10.1016/j.polymer.2011.09.038

Controlled polymerisation of lactide using an organo-catalyst in supercritical carbon dioxide

Blakey, Idriss, Yu, Anguang, Howdle, Steven M., Whittaker, Andrew K. and Thurecht, Kristofer J. (2011). Controlled polymerisation of lactide using an organo-catalyst in supercritical carbon dioxide. Green Chemistry, 13 (8), 2032-2037. doi: 10.1039/c1gc15344g

Biodegradable core-shell materials via RAFT and ROP: Characterization and comparison of hyperbranched and microgel particles

Zheng, Yu, Turner, William, Zong, Mengmeng, Irvine, Derek J., Howdle, Steven M. and Thurecht, Kristofer J. (2011). Biodegradable core-shell materials via RAFT and ROP: Characterization and comparison of hyperbranched and microgel particles. Macromolecules, 44 (6), 1347-1354. doi: 10.1021/ma1027092

Modular construction of multifunctional bioresponsive cell-targeted nanoparticles for gene delivery

Saeed, Aram O., Magnusson, Johannes P., Moradi, Emilia, Soliman, Mahmoud, Wang, Wenxin, Stolnik, Snow, Thurecht, Kristofer J., Howdle, Steven M. and Alexander, Cameron (2011). Modular construction of multifunctional bioresponsive cell-targeted nanoparticles for gene delivery. Bioconjugate Chemistry, 22 (2), 156-168. doi: 10.1021/bc100149g

NMR as a probe of nanostructured domains in ionic liquids : Does domain segregation explain increased performance of free radical polymerisation?

Puttick, Simon, Davis, Adrienne L., Butler, Kevin, Lambert, Lynette, El Harfi, Jaouad, Irvine, Derek J., Whittaker, Andrew K., Thurecht, Kristofer J. and Licence, Peter (2011). NMR as a probe of nanostructured domains in ionic liquids : Does domain segregation explain increased performance of free radical polymerisation?. Chemical Science, 2 (9), 1810-1816. doi: 10.1039/c1sc00207d

Polysiloxanes polymers with hyperbranched structure and multivinyl functionality

Zheng, Yu, Thurecht, Kristofer J. and Wang, Wenxin (2011). Polysiloxanes polymers with hyperbranched structure and multivinyl functionality. Journal of Polymer Science Part A: Polymer Chemistry, Article in press (4), 1-9. doi: 10.1002/pola.25072

Responsive hybrid block co-polymer conjugates of proteins-controlled architecture to modulate substrate specificity and solution behaviour

Yasayan, Gokcen, Saeed, Aram O., Fernandez-Trillo, Francisco, Allen, Stephanie, Davies, Martin C., Jangher, Abdulhakim, Paul, Alison, Thurecht, Kristofer J., King, Stephen M., Schweins, Ralf, Griffiths, Peter C., Magnusson, Johannes P. and Alexander, Cameron (2011). Responsive hybrid block co-polymer conjugates of proteins-controlled architecture to modulate substrate specificity and solution behaviour. Polymer Chemistry, 2 (7), 1567-1578. doi: 10.1039/c1py00128k

'Isothermal' phase transitions and supramolecular architecture changes in thermoresponsive polymers via acid-labile side-chains

Heath, Felicity, Saeed, Aram Omer, Pennadam, Sivanand S., Thurecht, Kristofer J. and Alexander, Cameron (2010). 'Isothermal' phase transitions and supramolecular architecture changes in thermoresponsive polymers via acid-labile side-chains. Polymer Chemistry, 1 (8), 1252-1262. doi: 10.1039/c0py00080a

Influence of compatibilizing agent molecular structure on the mechanical properties of phosphate glass fiber-reinforced PLA composites

Haque, Papia, Barker, Ian A., Parsons, Andrew, Thurecht, Kristofer J., Ahmed, Ifty, Walker, Gavin S., Rudd, Christopher D. and Irvine, Derek J. (2010). Influence of compatibilizing agent molecular structure on the mechanical properties of phosphate glass fiber-reinforced PLA composites. Journal of Polymer Science, Part A: Polymer Chemistry, 48 (14), 3082-3094. doi: 10.1002/pola.24086

Functional hyperbranched polymers: Toward targeted in Vivo F-19 magnetic resonance imaging using designed macromolecules

Thurecht, Kristofer J., Blakey, Idriss, Peng, Hui, Squires, Oliver, Hsu, Steven, Alexander, Cameron and Whittaker, Andrew K. (2010). Functional hyperbranched polymers: Toward targeted in Vivo F-19 magnetic resonance imaging using designed macromolecules. Journal of the American Chemical Society, 132 (15), 5336-5337. doi: 10.1021/ja100252y

High-pressure real-time Xe-129 NMR: Monitoring of surfactant conformation during the self-assembly of reverse micelles in supercritical carbon dioxide

Blakey, Idriss, Thurecht, Kristofer J. and Whittaker, Andrew K. (2010). High-pressure real-time Xe-129 NMR: Monitoring of surfactant conformation during the self-assembly of reverse micelles in supercritical carbon dioxide. Chemical Communications, 46 (16), 2850-2852. doi: 10.1039/b927029a

Temperature dependence of the dielectric properties of 2,2'-azobis(2- methyl-butyronitrile)(AMBN)

Smith, Alastair D., Lester, Edward H., Thurecht, Kristofer J., Kingman, Sam W., El Harfi, Jaouad, Dimitrakis, Georgios, Robinson, John P. and Irvine, Derek J. (2010). Temperature dependence of the dielectric properties of 2,2'-azobis(2- methyl-butyronitrile)(AMBN). Industrial and Engineering Chemistry Research, 49 (6), 3011-3014. doi: 10.1021/ie901389a

Synthesis and phase behavior of CO2-soluble hydrocarbon copolymer: Poly(vinyl) acetate-alt-dibutyl maleate

Lee, Hyunsuk, Pack, Ji Won, Wang, Wenxin, Thurecht, Kristofer J. and Howdle, Steven M. (2010). Synthesis and phase behavior of CO2-soluble hydrocarbon copolymer: Poly(vinyl) acetate-alt-dibutyl maleate. Macromolecules, 43 (5), 2276-2282. doi: 10.1021/ma902505h

Dielectric properties of free-radical polymerizations: Molecularly symmetrical initiators during thermal decomposition

Smith, Alastair D., Lester, Edward, Thurecht, Kristofer James, El Harfi, Jaouad, Dimitrakis, Georgios, Kingman, Sam W., Robinson, John P. and Irvine, Derek J. I (2010). Dielectric properties of free-radical polymerizations: Molecularly symmetrical initiators during thermal decomposition. Industrial and Engineering Chemistry Research, 49 (4), 1703-1710. doi: 10.1021/ie901201h

Preparation of sodium-capped poly(lactic acid) oligomers by catalytic initiation with a sodium α-, β-, or γ-hydroxyacidss

Hill, Gavin T. H., Irvine, Derek J., Thurecht, Kristofer J, Botting, Catherine H., Williamson, Sylvia and Cole-Hamilton, David J. (2010). Preparation of sodium-capped poly(lactic acid) oligomers by catalytic initiation with a sodium α-, β-, or γ-hydroxyacidss. Macromolecules, 43 (1), 185-192. doi: 10.1021/ma901861u

Controlled dispersion polymerization in supercritical carbon dioxide

Thurecht, K.J. and Howdle, S.M. (2009). Controlled dispersion polymerization in supercritical carbon dioxide. Australian Journal of Chemistry: an international journal for chemical science, 62 (8), 786-789. doi: 10.1071/CH09081

One-pot controlled synthesis of biodegradable and biocompatible co-polymer micelles

Saeed, Aram Omer, Dey, Sabrina, Howdle, Steven M., Thurecht, Kristofer J. and Alexander, Cameron (2009). One-pot controlled synthesis of biodegradable and biocompatible co-polymer micelles. Journal of Materials Chemistry, 19 (26), 4529-4535. doi: 10.1039/b821736j

RAFT-functional ionic liquids: towards understanding controlled free radical polymerisation in ionic liquids

Puttick, Simon, Irvine, Derek J., Licence, Peter and Thurecht, Kristofer J. (2009). RAFT-functional ionic liquids: towards understanding controlled free radical polymerisation in ionic liquids. Journal of Materials Chemistry, 19 (18), 2679-2682. doi: 10.1039/b817181p

Dispersion polymerisation in supercritical CO2 using macro-RAFT agents

Zong, Mengmeng, Thurecht, Kristofer J. and Howdle, Steven M. (2008). Dispersion polymerisation in supercritical CO2 using macro-RAFT agents. Chemical Communications (45), 5942-5944. doi: 10.1039/b812827h

Epoxy functionalised poly(epsilon-caprolactone): Synthesis and application

Zhou, Jiaxiang, Wang, Wenxin, Villarroya, Silvia, Thurecht, Kristofer J. and Howdle, Steven M. (2008). Epoxy functionalised poly(epsilon-caprolactone): Synthesis and application. Chemical Communications (44), 5806-5808. doi: 10.1039/b810297j

Successful dispersion polymerization in supercritical CO2 using polyvinylalkylate hydrocarbon surfactants synthesized and anchored via RAFT

Lee, Hyunsuk, Terry, Elaine, Zong, Mengmeng, Arrowsmith, Nicholas, Perrier, Sébastien, Thurecht, Kristofer J. and Howdle, Steven M. (2008). Successful dispersion polymerization in supercritical CO2 using polyvinylalkylate hydrocarbon surfactants synthesized and anchored via RAFT. Journal of the American Chemical Society, 130 (37), 12242-12243. doi: 10.1021/ja8046156

HRP-mediated inverse emulsion polymerisation of acrylamide in supercritical carbon dioxide

Villarroya, Silvia, Thurecht, Kristofer J. and Howdle, Steven M. (2008). HRP-mediated inverse emulsion polymerisation of acrylamide in supercritical carbon dioxide. Green Chemistry, 10 (8), 863-867. doi: 10.1039/b804080j

Free-radical polymerization in ionic liquids: the case for a protected radical

Thurecht, Kristofer J., Gooden, Peter N., Goel, Sarika, Tuck, Christopher, Licence, Peter and Irvine, Derek J. (2008). Free-radical polymerization in ionic liquids: the case for a protected radical. Macromolecules, 41 (8), 2814-2820. doi: 10.1021/ma7026403

Controlled dispersion polymerization of methyl methacrylate in supercritical carbon dioxide via RAFT

Gregory, Andrew M., Thurecht, Kristofer J. and Howdle, Steven M. (2008). Controlled dispersion polymerization of methyl methacrylate in supercritical carbon dioxide via RAFT. Macromolecules, 41 (4), 1215-1222. doi: 10.1021/ma702017r

“Living” Polymer Beads in Supercritical CO2

Thurecht, Kristofer J., Gregory, Andrew M., Wang, Wenxin and Howdle, Steven M. (2007). “Living” Polymer Beads in Supercritical CO2. Macromolecules, 40 (9), 2965-2967. doi: 10.1021/ma062724m

One-step chemoenzymatic synthesis of poly(epsilon-caprolactone-block-methyl methacrylate) in supercritical CO2. (vol 39, pg 5352, 2006)

Zhou, Jiaxiang, Villarroya, Silvia, Wang, Wenxin, Wyatt, Mark F., Duxbury, Christopher J., Thurecht, Kristofer J. and Howdle, Steven M. (2007). One-step chemoenzymatic synthesis of poly(epsilon-caprolactone-block-methyl methacrylate) in supercritical CO2. (vol 39, pg 5352, 2006). Macromolecules, 40 (6), 2276-2276. doi: 10.1021/ma070151n

Controlled dispersion polymerization in supercritical carbon dioxide by RAFT

Gregory, Andrew M., Thurecht, Kristofer J. and Howdle, Steven M. (2007). Controlled dispersion polymerization in supercritical carbon dioxide by RAFT. Polymer Preprints, 48 (2), 200-201.

GECO-DOSY Post-Processing Analysis of Polymers

Thurecht, Kristofer J., Howdle, Steven M., Davis, Adrienne L. and Hyde, Jason R. (2007). GECO-DOSY Post-Processing Analysis of Polymers. Macromolecules, 40 (4), 976-982. doi: 10.1021/ma061345q

Novel one pot synthesis of silver nanoparticle–polymer composites by supercritical CO2 polymerisation in the presence of a RAFT agent

Hasell, Tom, Thurecht, Kristofer J., Jones, Rhys D. W., Brown, Paul D. and Howdle, Steven M. (2007). Novel one pot synthesis of silver nanoparticle–polymer composites by supercritical CO2 polymerisation in the presence of a RAFT agent. Chemical communications, 38 (38), 3933-3935. doi: 10.1039/b710503g

Supercritical CO2: an effective medium for the chemo-enzymatic synthesis of block copolymers

Villarroya, Silvia, Thurecht, Kristofer J., Heise, Andreas and Howdle, Steven M. (2007). Supercritical CO2: an effective medium for the chemo-enzymatic synthesis of block copolymers. Chemical communications, 37 (37), 3805-3813. doi: 10.1039/b701128h

Synthesis of graft copolymers by the combination of ATRP and Enzymatic ROP in scC02

Villarroya, Silvia, Zhou, Jiaxiang, Thurecht, Kristofer J. and Howdle, Steven M. (2006). Synthesis of graft copolymers by the combination of ATRP and Enzymatic ROP in scC02. Macromolecules, 39 (26), 9080-9086. doi: 10.1021/ma061068n

Investigation of spontaneous microemulsion formation in supercritical carbon dioxide using high-pressure NMR

Thurecht, Kristofer J., Hill, David J. T. and Whittaker, Andrew K. (2006). Investigation of spontaneous microemulsion formation in supercritical carbon dioxide using high-pressure NMR. Journal of Supercritical Fluids, 38 (1), 111-118. doi: 10.1016/j.supflu.2005.11.021

One-step chemoenzymatic synthesis of poly(ε-caprolactone-block-methyl methacrylate) in supercritical CO2

Zhou, Jiaxiang, Villarroya, Silvia, Wang, Wenxin, Wyatt, Mark F., Duxbury, Christopher J., Thurecht, Kristofer J. and Howdle, Steven M. (2006). One-step chemoenzymatic synthesis of poly(ε-caprolactone-block-methyl methacrylate) in supercritical CO2. Macromolecules, 39 (16), 5352-5358. doi: 10.1021/ma060046y

Enzymatic polymerizations in supercritical carbon dioxide

Villarroya, Silvia, Zhou, Jiaxiang, Thurecht, Kristofer J. and Howdle, Steven M. (2006). Enzymatic polymerizations in supercritical carbon dioxide. Polymer Preprints, 47 (2), 231-232.

Kinetics of Enzymatic Ring-Opening Polymerization of ε-Caprolactone in Supercritical Carbon Dioxide

Thurecht, Kristofer J., Heise, Andreas, deGeus, Matthijs, Villarroya, Silvia, Zhou, Jiaxiang, Wyatt, Mark F. and Howdle, Steven M. (2006). Kinetics of Enzymatic Ring-Opening Polymerization of ε-Caprolactone in Supercritical Carbon Dioxide. Macromolecules, 39 (23), 7967-7972. doi: 10.1021/ma061310q

NMR microscopy: A tool for measuring monomer diffusion in supercritical CO2

Thurecht, Kistofer J., T Hill, David J. and Whittaker, Andrew K. (2006). NMR microscopy: A tool for measuring monomer diffusion in supercritical CO2. Macromolecular Chemistry And Physics, 207 (17), 1539-1545. doi: 10.1002/macp.200600245

Simultaneous Dynamic Kinetic Resolution in Combination with Enzymatic Ring-Opening Polymerization

Zhou, Jiaxiang, Wang, Wenxin, Thurecht, Kristofer J., Villarroya, Silvia and Howdle, Steven M. (2006). Simultaneous Dynamic Kinetic Resolution in Combination with Enzymatic Ring-Opening Polymerization. Macromolecules, 39 (21), 7302-7305. doi: 10.1021/ma0614388

Simultaneous enzymatic ring opening polymerisation and RAFT-mediated polymerisation in supercritical CO2

Thurecht, Kristofer J., Gregory, Andrew M., Villarroya, Silvia, Zhou, Jiaxiang, Heise, Andreas and Howdle, Steven M. (2006). Simultaneous enzymatic ring opening polymerisation and RAFT-mediated polymerisation in supercritical CO2. Chemical Communications, 42 (42), 4383-4385. doi: 10.1039/b611626d

Equilibrium swelling measurements of network and semicrystalline polymers in supercritical carbon dioxide using high-pressure NMR

Thurecht, K. J., Hill, D. J. T. and Whittaker, A. K. (2005). Equilibrium swelling measurements of network and semicrystalline polymers in supercritical carbon dioxide using high-pressure NMR. Macromolecules, 38 (9), 3731-3737. doi: 10.1021/ma0503108

Determination of domain sizes in blends of poly(ethylene) and poly(styrene) formed in the presence of supercritical carbon dioxide

Thurecht, K. J., Hill, D. J. T., Preston, C. M. L., Rintoul, L., White, J. W. and Whittaker, A. K. (2004). Determination of domain sizes in blends of poly(ethylene) and poly(styrene) formed in the presence of supercritical carbon dioxide. Macromolecules, 37 (16), 6019-6026. doi: 10.1021/ma0492622

New structure formation on gamma-irradiation of poly(chlorotrifluoroethylene)

Hill, D. J. T., Thurecht, K. J. and Whittaker, A. K. (2003). New structure formation on gamma-irradiation of poly(chlorotrifluoroethylene). Radiation Physics And Chemistry, 67 (6), 729-736. doi: 10.1016/S0969-806X(03)00004-5

A study of the radiation chemistry of poly(chlorotrifluoroethylene) by ESR spectroscopy

Hill, D. J. T., Thurecht, K. J. and Whittaker, A. K. (2003). A study of the radiation chemistry of poly(chlorotrifluoroethylene) by ESR spectroscopy. Radiation Physics And Chemistry, 68 (5), 857-864. doi: 10.1016/S0969-806X(03)00313-X

NMR studies of polymers formed in and within supercritical CO2.

Whittaker, AK, Hill, DJT and Thurecht, K (2003). NMR studies of polymers formed in and within supercritical CO2.. Abstracts of Papers of The American Chemical Society, 225, U591-U591.

Immuno-PET agents for targeting glioblastoma

Ghosh, S., Huda, P., Fletcher, N., Howard, C., Lu, Y., Campbell, D., Walsh, B. and Thurecht, K. (2022). Immuno-PET agents for targeting glioblastoma. Australian and New Zealand Society of Nuclear Medicine (ANZSNM) 52nd ASM, Brisbane, QLD, Australia, 13–15 May 2022. Richmond, VIC, Australia: John Wiley & Sons.

Canine PET/CT imaging with 64Cu-nanomedicines

Daniel, Sarah, Houston, Zachary, Fletcher, Nicholas, Bell, Craig, Atcheson, Nicole, Al-Najjar, Aiman, Howard, Christopher, Mahler, Stephen, Straw, Rod and Thurecht, Kristofer (2020). Canine PET/CT imaging with 64Cu-nanomedicines. SNMMI Annual Meeting, Online, 11-14 July, 2020. Reston, VA, United States: Society of Nuclear Medicine.

Innovation in diagnosis and treatment of brain metastases using multifunctional nanomedicines

Saunus, J. M., Lim, M., Puttick, S., Croft, P. Kalita-de, Houston, Z. H., Jones, M. L., Latter, M. J., Campbell, L. C., Thomas, P., Jeffree, R. L., Rose, S. E., Mahler, S. M., Thurecht, K. J., Scott, A. M. and Lakhani, S. R. (2019). Innovation in diagnosis and treatment of brain metastases using multifunctional nanomedicines. San Antonio Breast Cancer Symposium, San Antonio, Texas, 4-8 December 2018. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS18-P1-19-02

Targeted beta therapy of human prostate cancer in vivo with Lu-177 labelled MIL-38 antibody against glypican-1 (GPC-1)

Yeh, Mei-Chun, Tse, Brian W. C., Fletcher, Nicholas L., Huston, Zachary H., Stewart, Chelsea, Sokolowski, Kamil, Jeet, Varinder, Wissmueller, Sandra, Thurecht, Kristofer J., Campbell, Douglas H., Walsh, Bradley J., Nelson, Colleen C. and Russell, Pamela J. (2018). Targeted beta therapy of human prostate cancer in vivo with Lu-177 labelled MIL-38 antibody against glypican-1 (GPC-1). 19th Asia-Pacific Prostate Cancer Conference, Brisbane Australia, Aug 22-25, 2018. HOBOKEN: WILEY.

EPHA3 a novel tumour specific therapeutic target for medulloblastoma

Offenhauser, Carolin, Carrington, Benjamin, Thurecht, Kris, Ensbey, Kathleen, Bruce, Zara, Jamieson, Paul, Lim, Yi Chieh, Akgul, Seckin, Li, Michelle, Stringer, Brett, Puttick, Simon, Fuchs, Adrian, Picard, Daniel, Ingram, Wendy, Hallahan, Andrew, Moore, Andrew, Johns, Terrance, Gottardo, Nicholas, Remke, Marc, Boyd, Andrew and Day, Bryan (2018). EPHA3 a novel tumour specific therapeutic target for medulloblastoma. 18th International Symposium on Pediatric Neuro-Oncology (ISPNO), Denver, CO USA, 30 June-3 July 2018. Cary, NC USA: Oxford University Press.

Design-led 3D visualization of nanomedicines in virtual reality

Lilja, Andrew R., Strong, Campbell W., Bailey, Benjamin J., Thurecht, Kristofer J., Houston, Zachary H., Fletcher, Nicholas L. and McGhee, John B. (2018). Design-led 3D visualization of nanomedicines in virtual reality. 24th ACM Symposium on Virtual Reality Software and Technology (ACM VRST), Tokyo, Japan, Nov 28- Dec 01 2018. New York, NY, United States: Association for Computing Machinery. doi: 10.1145/3281505.3281572

Development of polymer theranostics to probe the behaviour of nanomaterials in biology

Thurecht, Kristofer, Zhou, Yongmei, Fletcher, Nicholas and Houston, Zachary (2018). Development of polymer theranostics to probe the behaviour of nanomaterials in biology. 255th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nexus of Food, Energy, and Water, New Orleans, LA United States, 18-22 March 2018. Washington, DC United States: American Chemical Society.

Development of polymeric MRI agents as theranostics

Thurecht, Kristofer, Fuchs, Adrian, Bapat, Abhijeet and Houston, Zachary (2018). Development of polymeric MRI agents as theranostics. 255th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nexus of Food, Energy, and Water, New Orleans, LA United States, 18-22 March 2018. Washington, DC United States: American Chemical Society.

Harnessing shape and bi-specific antibodies for improved cell-targeting efficiency of poly(ethylene glycol) capsules

Song, Danzi, Cui, Jiwei, Ju, Yi, Sun, Huanli, Thurecht, Kristofer and Caruso, Frank (2017). Harnessing shape and bi-specific antibodies for improved cell-targeting efficiency of poly(ethylene glycol) capsules. 253rd National Meeting of the American-Chemical-Society (ACS) on Advanced Materials, Technologies, Systems, and Processes, San Francisco, CA USA, 2-6 April 2017. Washington, DC USA: American Chemical Society.

EphA receptor tyrosine kinases as targets for therapy in paediatric medulloblastoma

Carrington, Benjamin, Al-Ejeh, Fares, Lim, Yi Chieh, Ensbey, Kathleen, Bruce, Zara, Jamieson, Paul, Fuchs, Adrian, Thurecht, Kristofer, Stringer, Brett, Boyd, Andrew and Day, Bryan (2016). EphA receptor tyrosine kinases as targets for therapy in paediatric medulloblastoma. 21st Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology, Scottsdale, AZ, United States, 17-20 November 2016. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/neuonc/now212.638

Evaluation of the in vivo fate of ultrapure alginate in mice model

Anitha, A., Fletcher, Nicholas, Houston, Zachary, Thurecht, Kristofer and Grondahl, Lisbeth (2016). Evaluation of the in vivo fate of ultrapure alginate in mice model. 10th World Biomaterials Congress, Montréal, Canada, 17 May - 22 May 2016. Lausanne, Switzerland: Frontiers Research Foundation. doi: 10.3389/conf.FBIOE.2016.01.02237

MILGa-01-a first in human study assessing the safety and tolerability of chMIL-38 in prostate cancer

Sabanathan, Dhanusha, Gurney, Howard, Gillatt, David, Trifunovic, Marko, Magnussen, John, Poursoultan, Pirooz, Shon, Kevin H. O., Walsh, Bradley J., Mazure, Hubert, Velonas, Vicki, Thurecht, Kris, Quach Truong, Wissmueller, Sandra and Campbell, Douglas (2016). MILGa-01-a first in human study assessing the safety and tolerability of chMIL-38 in prostate cancer. 17th Asia-Pacific Prostate Cancer Conference, Melbourne Australia, August 31 - September 3 2016. United Kingdom: Wiley-Blackwell.

Targeted multimodal hyperbranched polymers for imaging and therapy of prostate cancer

Tse, Brian W-C, Pearce, Amanda, Fuchs, Adrian V., Simpson, Joshua D., Yeh, Mei-Chun, Huang, Steve S., Heston, Warren D. W., Williams, Elizabeth D., Whittaker, Andrew K., Thurecht, Kristofer J. and Russell, Pamela J. (2016). Targeted multimodal hyperbranched polymers for imaging and therapy of prostate cancer. 17th Asia-Pacific Prostate Cancer Conference, Melbourne Australia, August 31-September 3 2016. United Kingdom: Wiley-Blackwell.

Mapping the lyotropic phase behavior of diblock copolymer iongels

Bennett, Thomas, Blakey, Idriss, Thurecht, Kristofer and Jack, Kevin (2015). Mapping the lyotropic phase behavior of diblock copolymer iongels. American Chemical Society Meeting, American Chemical Society.

Multimodal hyperbranched polymers targeting prostate specific membrane antigen (PSMA) for imaging of prostate cancer

Tse, Brian W-C, Fuchs, Adrian V., Huang, Steve S., Heston, Warren D. W., Yeh, Mei-Chun, Whittaker, Andrew K., Thurecht, Kristofer J. and Russell, Pamela J. (2015). Multimodal hyperbranched polymers targeting prostate specific membrane antigen (PSMA) for imaging of prostate cancer. 2nd Prostate Cancer World Congress (PCWC), Cairns, Australia, 17-21 August 2015. HOBOKEN: WILEY-BLACKWELL.

Polymeric MRI agents for disease detection: advances and challenges

Zhang, Cheng , Wang, Kewei , Peng, Hui , Puttick, Simon , Thurecht, Kris and Whittaker, Andrew (2015). Polymeric MRI agents for disease detection: advances and challenges. 2015 International Chemical Congress of Pacific Basin Societies, Honolulu, Hawaii, United States, 15-20 December 2015.

Solution properties of EOGMA-containing macromolecules

Zhang, Cheng, Wang, Kewei, Thurecht, Kris, Puttick, Simon, Peng, Hui and Whittaker, Andrew (2015). Solution properties of EOGMA-containing macromolecules. 4th Federation of Asian Polymer Societies – International Polymer Congress, Kuala Lumpur, Malaysia, 5-8 October 2015. Weinheim, Germany:

EphA2 as a diagnostic imaging target in glioblastoma: a PET/MRI study

Puttick, Simon, Stringer, Brett W., Day, Bryan W., Mardon, Karine, Cowin, Gary J., Fay, Michael, Thurecht, Kristofer J., Whittaker, Andrew K., Boyd, Andrew W. and Rose, Stephen (2014). EphA2 as a diagnostic imaging target in glioblastoma: a PET/MRI study. 105th Annual Meeting of the American Association for Cancer Research (AACR), San Diego, CA, United States, 5-9 April 2014. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2014-LB-12

Extending the scope of poly(styrene)-block-poly(methyl methacrylate) for directed self assembly

Bennett, Thomas, Pei, Kevin, Cheng, Han-Hao, Thurecht, Kristofe J., Jack, Kevin S. and Blakey, Idriss (2014). Extending the scope of poly(styrene)-block-poly(methyl methacrylate) for directed self assembly. Alternative Lithographic Technologies VI, San Jose, United States, 24-27 February 2014. Bellingham, WA, United States: SPIE. doi: 10.1117/12.2046296

Multimodal hyperbranched polymers for simultaneous imaging and drug delivery for targeted prostate cancer theranostics

Fuchs, Adrian V., Pearce, Amanda K., Tse, Brian W. C., Whittaker, Andrew K., Russell, Pamela J. and Thurecht, Kristofer J. (2014). Multimodal hyperbranched polymers for simultaneous imaging and drug delivery for targeted prostate cancer theranostics. ACS 2014: 247th American Chemical Society National Meeting & Exposition, Dallas, TX, USA, 16-20 March, 2014. Washington, DC, United States: American Chemical Society.

SERS-barcoded colloidal gold NP assemblies as imaging agents for use in biodiagnostics

Dey, Priyanka, Olds, William, Blakey, Idriss, Thurecht, Kristofer J., Izake, Emad L. and Fredericks, Peter M. (2014). SERS-barcoded colloidal gold NP assemblies as imaging agents for use in biodiagnostics. Biomedical Vibrational Spectroscopy VI: Advances in Research and Industry, San Francisco, CA United States, 1-2 February 2014. Bellingham, WA United States: SPIE. doi: 10.1117/12.2037159

Biologically-responsive polymeric F-19 MRI agents

Whittaker, Andrew K., Thurecht, Kristofer J., Blakey, Idriss and Peng, Hui (2013). Biologically-responsive polymeric F-19 MRI agents. 245th National Spring Meeting of the American-Chemical-Society (ACS), New Orleans LA, 07-11 April 2013. Washington, DC United States: American Chemical Society.

Hyperbranched polymers in theranostics: Development of advanced delivery probes for cancer therapy

Thurecht, Kristofer J., Whittaker, Andrew K., Russell, Pamela J. and Pearce, Amanda (2013). Hyperbranched polymers in theranostics: Development of advanced delivery probes for cancer therapy. 245th National Spring Meeting of the American-Chemical-Society (ACS), New Orleans LA, 07-11 April 2013. Washington, DC United States: American Chemical Society.

POLY 252-RAFT-functional ionic liquids: Controlled free radical polymerization in ionic liquids

Thurecht, Krisofer J., Puttick, Simon, Irvine, Derek J. and Licence, Peter (2009). POLY 252-RAFT-functional ionic liquids: Controlled free radical polymerization in ionic liquids. American Chemical Society National Meeting, Salt Lake City, UT, U.S.A., 22 -26 March 2009. Washington, DC United States: American Chemical Society.

High pressure NMR of polymeric materials

Whittaker, Andrew K., Blakey, Idriss, Thurecht, Kristofer J., Squires, Oliver and Varcoe, Kylie (2008). High pressure NMR of polymeric materials. 235th American Chemical Society National Meeting, New Orleans, 6-10 April 2008 . Blacksburg, VA, United States: American Chemical Society.

POLY 624-High pressure NMR of polymeric materials

Whittaker, AK, Blakey, I, Thurecht, KJ, Squires, O and Varcoe, K (2008). POLY 624-High pressure NMR of polymeric materials. 235th American-Chemical-Society National Meeting, New Orleans LA, APR 06-10, 2008. WASHINGTON: AMER CHEMICAL SOC.

Application of Raman Spectroscopic Mapping for the Characterisation of High Performance Polymers

Rintoul, L., Thurecht, K., Chen, L., Goh, K., Hill, D. J. T. and Whittaker, A. K. (2003). Application of Raman Spectroscopic Mapping for the Characterisation of High Performance Polymers. 5th Australian Conference on Vibrational Spectroscopy, Melbourne, 29 Sep - 2 Oct 2003. CSIRO.

Aspects of the radiation chemistry of poly(chlorotrifluoroethylene)

Hill, D. J. T., Thurecht, K. J. and Whittaker, A. K. (2002). Aspects of the radiation chemistry of poly(chlorotrifluoroethylene). 25th Australasian Polymer Symposium, Armidale, 10-13 February, 2002.

Radiation chemistry of poly(chlorotrifluoroethylene) for biomedical purposes

Hill, D. J. T., Thurecht, K. J. and Whittaker, A. K. (2002). Radiation chemistry of poly(chlorotrifluoroethylene) for biomedical purposes. Qld Polymer Group Satellite Symposium, Brisbane, 6-8 February, 2002.

Nuclear magnetic resonance agent

Whittaker, A. K., Peng, H., Thurecht, K. J. and Blakey, I. (2012). Nuclear magnetic resonance agent. 2012-AU415 2012142670.

Synthesis and characterisation of polymers using supercritical carbon dioxide and NMR

Thurecht, K J (2005). Synthesis and characterisation of polymers using supercritical carbon dioxide and NMR. PhD Thesis, School of Molecular and Microbial Sciences, The University of Queensland.