The University of Queensland

Application of antibiotic-derived fluorescent probes to bacterial studies

Zhang, Bing, Stone, M. Rhia L., Kc, Sanjaya, Łapińska, Urszula, Pagliara, Stefano and Blaskovich, Mark A.T. (2022). Application of antibiotic-derived fluorescent probes to bacterial studies. Methods in enzymology. (pp. 1-28) edited by Erin E. Carlson. San Diego, CA, United States: Academic Press. doi: 10.1016/bs.mie.2021.11.010

Direct assessment of nitrative stress in lipid environments: Applications of a designer lipid-based biosensor for peroxynitrite

Gutierrez, Bryan, Aggarwal, Tushar, Erguven, Huseyin, Stone, M. Rhia L., Guo, Changjiang, Bellomo, Alyssa, Abramova, Elena, Stevenson, Emily R., Laskin, Debra L., Gow, Andrew J. and Izgu, Enver Cagri (2023). Direct assessment of nitrative stress in lipid environments: Applications of a designer lipid-based biosensor for peroxynitrite. iScience, 26 (12) 108567, 1-23. doi: 10.1016/j.isci.2023.108567

Synthesis of vancomycin fluorescent probes that retain antimicrobial activity, identify Gram-positive bacteria, and detect Gram-negative outer membrane damage

Zhang, Bing, Phetsang, Wanida, Stone, M. Rhia L., Kc, Sanjaya, Butler, Mark S., Cooper, Matthew A., Elliott, Alysha G., Łapińska, Urszula, Voliotis, Margaritis, Tsaneva-Atanasova, Krasimira, Pagliara, Stefano and Blaskovich, Mark A. T. (2023). Synthesis of vancomycin fluorescent probes that retain antimicrobial activity, identify Gram-positive bacteria, and detect Gram-negative outer membrane damage. Communications Biology, 6 (1) 409, 1-16. doi: 10.1038/s42003-023-04745-x

Bioorthogonal functionalization of material surfaces with bioactive molecules

Hast, Kern, Stone, M. Rhia L., Jia, Zhaojun, Baci, Melih, Aggarwal, Tushar and Izgu, Enver Cagri (2023). Bioorthogonal functionalization of material surfaces with bioactive molecules. ACS Applied Materials and Interfaces, 15 (4), 4996-5009. doi: 10.1021/acsami.2c20942

Fast bacterial growth reduces antibiotic accumulation and efficacy

Łapińska, Urszula, Voliotis, Margaritis, Lee, Ka Kiu, Campey, Adrian, Stone, Rhia M. L., Tuck, Brandon, Phetsang, Wanida, Zhang, Bing, Tsaneva-Atanasova, Krasimira, Blaskovich, Mark A. T. and Pagliara, Stefano (2022). Fast bacterial growth reduces antibiotic accumulation and efficacy. eLife, 11 e74062, 1-33. doi: 10.7554/ELIFE.74062

CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage

Conners, Rebecca, McLaren, Mathew, Łapińska, Urszula, Sanders, Kelly, Stone, M. Rhia L., Blaskovich, Mark A. T., Pagliara, Stefano, Daum, Bertram, Rakonjac, Jasna and Gold, Vicki A. M. (2021). CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage. Nature Communications, 12 (1) 6316, 6316. doi: 10.1038/s41467-021-26610-3

Serum complement activation by C4BP-IgM fusion protein can restore susceptibility to antibiotics in Neisseria gonorrhoeae

Bettoni, Serena, Maziarz, Karolina, Stone, M. Rhia L., Blaskovich, Mark A. T., Potempa, Jan, Bazzo, Maria Luiza, Unemo, Magnus, Ram, Sanjay and Blom, Anna M. (2021). Serum complement activation by C4BP-IgM fusion protein can restore susceptibility to antibiotics in Neisseria gonorrhoeae. Frontiers in Immunology, 12 726801, 1-15. doi: 10.3389/fimmu.2021.726801

Route efficiency assessment and review of the synthesis of β-nucleosides: Via N -glycosylation of nucleobases

Kaspar, Felix, Stone, M. Rhia L., Neubauer, Peter and Kurreck, Anke (2021). Route efficiency assessment and review of the synthesis of β-nucleosides: Via N -glycosylation of nucleobases. Green Chemistry, 23 (1), 37-50. doi: 10.1039/d0gc02665d

Two for the price of one: heterobivalent ligand design targeting two binding sites on voltage-gated sodium channels slows ligand dissociation and enhances otency

Peschel, Alicia, Cardoso, Fernanda C., Walker, Andrew A., Durek, Thomas, Stone, M Rhia L., Braga Emidio, Nayara, Dawson, Philip E., Muttenthaler, Markus and King, Glenn F. (2020). Two for the price of one: heterobivalent ligand design targeting two binding sites on voltage-gated sodium channels slows ligand dissociation and enhances otency. Journal of Medicinal Chemistry, 63 (21), 12773-12785. doi: 10.1021/acs.jmedchem.0c01107

Visualization of bacterial resistance using fluorescent antibiotic probes

Stone, M. Rhia L., Phetsang, Wanida, Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). Visualization of bacterial resistance using fluorescent antibiotic probes. Journal of Visualized Experiments, 2020 (157) e60743. doi: 10.3791/60743

Fluorescent macrolide probes – synthesis and use in evaluation of bacterial resistance

Stone, M. Rhia L., Łapińska, Urszula, Pagliara, Stefano, Masi, Muriel, Blanchfield, Joanne T., Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). Fluorescent macrolide probes – synthesis and use in evaluation of bacterial resistance. RSC Chemical Biology, 1 (5), 395-404. doi: 10.1039/d0cb00118j

Non-antibiotic small-molecule regulation of DHFR-based destabilizing domains in vivo

Peng, Hui, Chau, Viet Q., Phetsang, Wanida, Sebastian, Rebecca M., Stone, M. Rhia L., Datta, Shyamtanu, Renwick, Marian, Tamer, Yusuf T., Toprak, Erdal, Koh, Andrew Y., Blaskovich, Mark A.T. and Hulleman, John D. (2019). Non-antibiotic small-molecule regulation of DHFR-based destabilizing domains in vivo. Molecular Therapy - Methods and Clinical Development, 15, 27-39. doi: 10.1016/j.omtm.2019.08.002

Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux

Stone, M. Rhia L., Masi, Muriel, Phetsang, Wanida, Pagès, Jean-Marie, Cooper, Matthew A. and Blaskovich, Mark A. T. (2019). Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux. MedChemComm, 10 (6), 901-906. doi: 10.1039/c9md00124g

Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance

Stone, M Rhia L., Butler, Mark S., Phetsang, Wanida, Cooper, Matthew A. and Blaskovich, Mark A. T. (2018). Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance. Trends in Biotechnology, 36 (5), 523-536. doi: 10.1016/j.tibtech.2018.01.004

ChemInform abstract: divergent synthesis of 2-C-branched pyranosides and oxepines from 1,2-gem-dibromocyclopropyl carbohydrates

Moore, Peter W., Schuster, Julia K., Hewitt, Russell J., Stone, M. Rhia L., Teesdale-Spittle, Paul H. and Harvey, Joanne E. (2015). ChemInform abstract: divergent synthesis of 2-C-branched pyranosides and oxepines from 1,2-gem-dibromocyclopropyl carbohydrates. ChemInform, 46 (8), 1-1. doi: 10.1002/chin.201508276

Divergent synthesis of 2-C-branched pyranosides and oxepines from 1,2-gem-dibromocyclopropyl carbohydrates

Moore, Peter W., Schuster, Julia K., Hewitt, Russell J., Stone, M. Rhia L., Teesdale-Spittle, Paul H. and Harvey, Joanne E. (2014). Divergent synthesis of 2-C-branched pyranosides and oxepines from 1,2-gem-dibromocyclopropyl carbohydrates. Tetrahedron, 70 (39), 7032-7043. doi: 10.1016/j.tet.2014.06.069

Antibiotic-derived molecular probes for bacterial imaging

Blaskovich, Mark A., Phetsang, Wanida, Stone, M. Rhia L., Lapinska, Urszula, Pagliara, Stefano, Bhalla, Rajiv and Cooper, Matthew A. (2019). Antibiotic-derived molecular probes for bacterial imaging. SPIE BiOS 2019, San Francisco, California, 2-7 February 2019. Bellingham, WA United States: SPIE - International Society for Optical Engineering. doi: 10.1117/12.2507329

Tagged Antibiotics for Examination of Bacterial Resistance and Infection

Stone, Magali (2020). Tagged Antibiotics for Examination of Bacterial Resistance and Infection. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. doi: 10.14264/uql.2020.937

Visualisation Constructs

Mark Blaskovich, Matt Cooper, Mark Butler, Rhia Stone and Wanida Phetsang (2018). Visualisation Constructs. WO/2018/102890.