The University of Queensland

Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis

Tu, Cui, Buckle, Irina, Leal Rojas, Ingrid, Rossi, Gustavo Rodrigues, Sester, David P, Moore, Andrew S, Radford, Kristen, Guillerey, Camille and Souza‐Fonseca‐Guimaraes, Fernando (2024). Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis. Clinical & Translational Immunology, 13 (3) e1501. doi: 10.1002/cti2.1501

Development of physiologically relevant skin organoids from human induced pluripotent stem cells

Shafiee, Abbas, Sun, Jane, Ahmed, Imaan A., Phua, Felicia, Rossi, Gustavo R., Lin, Cheng‐Yu, Souza‐Fonseca‐Guimaraes, Fernando, Wolvetang, Ernst J., Brown, Jason and Khosrotehrani, Kiarash (2023). Development of physiologically relevant skin organoids from human induced pluripotent stem cells. Small e2304879, 1-14. doi: 10.1002/smll.202304879

Differential regulation of natural killer cells by tumor necrosis factor receptors 1 and 2

McCulloch, Timothy R., Rossi, Gustavo Rodrigues, Lam, Allie, Wong, Joshua, Kane, Lawrence P, Herold, Marco, Wells, Timothy and Souza-Fonseca-Guimaraes, Fernando (2023). Differential regulation of natural killer cells by tumor necrosis factor receptors 1 and 2. The Journal of Immunology, 210 (S1), 72.28-72.28. doi: 10.4049/jimmunol.210.supp.72.28

Fucoidan from Spatoglossum schröederi promotes B16-F10 malignancy features modulation and antimelanoma in vivo activities

Bellan, D.L., Bini, I.H., Santi, F.C., Rossi, G.R., Biscaia, S.M.P., Maximo, A.I., Reis, M.B., Simas, F.F., Oliveira, C.C., Winnischofer, S.M.B., Leme, D.M., Chammas, R., Rocha, H.A.O. and Trindade, E.S. (2023). Fucoidan from Spatoglossum schröederi promotes B16-F10 malignancy features modulation and antimelanoma in vivo activities. Algal Research, 72 103134, 1-12. doi: 10.1016/j.algal.2023.103134

IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study

Shojaei, Maryam, Shamshirian, Amir, Monkman, James, Grice, Laura, Tran, Minh, Tan, Chin Wee, Teo, Siok Min, Rodrigues Rossi, Gustavo, McCulloch, Timothy R., Nalos, Marek, Raei, Maedeh, Razavi, Alireza, Ghasemian, Roya, Gheibi, Mobina, Roozbeh, Fatemeh, Sly, Peter D., Spann, Kirsten M., Chew, Keng Yih, Zhu, Yanshan, Xia, Yao, Wells, Timothy J., Senegaglia, Alexandra Cristina, Kuniyoshi, Carmen Lúcia, Franck, Claudio Luciano, dos Santos, Anna Flavia Ribeiro, Noronha, Lucia de, Motamen, Sepideh, Valadan, Reza, Amjadi, Omolbanin ... Tang, Benjamin (2023). IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study. Frontiers in Immunology, 13 1060438, 1-14. doi: 10.3389/fimmu.2022.1060438

A simple method to evaluate the toxic effects of Prorocentrum lima extracts to fish (sea bass) kidney cells

da Silva, Cesar Aparecido, Mafra, Luiz Laureno, Rossi, Gustavo Rodrigues, da Silva Trindade, Edvaldo and Matias, William Gerson (2022). A simple method to evaluate the toxic effects of Prorocentrum lima extracts to fish (sea bass) kidney cells. Toxicology in Vitro, 85 105476, 1-8. doi: 10.1016/j.tiv.2022.105476

Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy

Raza, Aun, Rossi, Gustavo Rodrigues, Janjua, Taskeen Iqbal, Souza-Fonseca-Guimaraes, Fernando and Popat, Amirali (2022). Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy. Trends in Biotechnology, 41 (1), 77-92. doi: 10.1016/j.tibtech.2022.06.011

TGF-β and CIS inhibition overcomes NK cell suppression to restore anti-tumor immunity

Souza-Fonseca Guimaraes, Fernando, Rossi, Gustavo R., Dagley, Laura F., Foroutan, Momeneh, McCulloch, Timothy R., Yousef, Jumana, Park, Hae-Young, Gunter, Jennifer H., Beavis, Paul A., Lin, Cheng-Yu, Hediyeh-zadeh, Soroor, Camilleri, Tania, Davis, Melissa J. and Huntington, Nicholas D. (2022). TGF-β and CIS inhibition overcomes NK cell suppression to restore anti-tumor immunity. Cancer Immunology Research, 10 (9), 1047-1054. doi: 10.1158/2326-6066.cir-21-1052

CIS and TGF ‐β regulatory pathways influence immunity to bacterial infection

McCulloch, Timothy R., Rossi, Gustavo R., Schreuder, Jaring, Belz, Gabrielle T., Wells, Timothy J. and Souza‐Fonseca‐Guimaraes, Fernando (2022). CIS and TGF ‐β regulatory pathways influence immunity to bacterial infection. Immunology, 167 (1), 54-63. doi: 10.1111/imm.13516

Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signatures

Kulasinghe, Arutha, Tan, Chin Wee, dos Santos Miggiolaro, Anna Flavia Ribeiro, Monkman, James, SadeghiRad, Habib, Bhuva, Dharmesh D., da Silva Motta Junior, Jarbas, Vaz de Paula, Caroline Busatta, Nagashima, Seigo, Baena, Cristina Pellegrino, Souza-Fonseca-Guimaraes, Paulo, de Noronha, Lucia, McCulloch, Timothy, Rodrigues Rossi, Gustavo, Cooper, Caroline, Tang, Benjamin, Short, Kirsty R., Davis, Melissa J., Souza-Fonseca-Guimaraes, Fernando, Belz, Gabrielle T. and O'Byrne, Ken (2022). Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signatures. European Respiratory Journal, 59 (6) 2101881, 1-19. doi: 10.1183/13993003.01881-2021

Enhancing natural killer cell targeting of pediatric sarcoma

Omer, Natacha, Nicholls, Wayne, Ruegg, Bronte, Souza-Fonseca-Guimaraes, Fernando and Rossi, Gustavo Rodrigues (2021). Enhancing natural killer cell targeting of pediatric sarcoma. Frontiers in Immunology, 12 791206, 791206. doi: 10.3389/fimmu.2021.791206

Electrospun polyvinyl-alcohol/gum arabic nanofibers: biomimetic platform for in vitro cell growth and cancer nanomedicine delivery

Serio, Francesca, da Cruz, Anderson Fraga, Chandra, Anil, Nobile, Concetta, Rossi, Gustavo Rodrigues, D'Amone, Eliana, Gigli, Giuseppe, del Mercato, Loretta Laureana and de Oliveira, Carolina Camargo (2021). Electrospun polyvinyl-alcohol/gum arabic nanofibers: biomimetic platform for in vitro cell growth and cancer nanomedicine delivery. International Journal of Biological Macromolecules, 188, 764-773. doi: 10.1016/j.ijbiomac.2021.08.069

Biocompatible gum arabic-gold nanorod composite as an effective therapy for mistreated melanomas

Gonçalves, Jenifer P., da Cruz, Anderson F., Nunes, Ábner M., Meneghetti, Mario R., de Barros, Heloise R., Borges, Beatriz S., de Medeiros, Lia C.A.S., Soares, Maurilio J., dos Santos, Mayara P., Grassi, Marco T., Rossi, Gustavo R., Bellan, Daniel L., Biscaia, Stellee M.P., Cristal, Aline M., Buzzo, João L.A., Ribeiro, Yasmin C., Acco, Alexandra, Cardoso, Mateus B., Simas, Fernanda F., Trindade, Edvaldo S., Riegel-Vidotti, Izabel C. and de Oliveira, Carolina C. (2021). Biocompatible gum arabic-gold nanorod composite as an effective therapy for mistreated melanomas. International Journal of Biological Macromolecules, 185, 551-561. doi: 10.1016/j.ijbiomac.2021.06.172

Production of a novel recombinant brown spider hyaluronidase in baculovirus-infected insect cells

De-Bona, Elidiana, Chaves-Moreira, Daniele, Batista, Thiago Beltrami Dias, Justa, Hanna Câmara da, Rossi, Gustavo Rodrigues, Antunes, Bruno Cesar, Matsubara, Fernando Hitomi, Minozzo, João Carlos, Wille, Ana Carolina Martins, Veiga, Silvio Sanches, Senff-Ribeiro, Andrea and Gremski, Luiza Helena (2021). Production of a novel recombinant brown spider hyaluronidase in baculovirus-infected insect cells. Enzyme and Microbial Technology, 146 109759, 1-13. doi: 10.1016/j.enzmictec.2021.109759

Green does not always mean go: a sulfated galactan from Codium isthmocladum green seaweed reduces melanoma metastasis through direct regulation of malignancy features

Bellan, D.L., Biscaia, S.M.P., Rossi, G.R., Cristal, A.M., Gonçalves, J.P., Oliveira, C.C., Simas, F.F., Sabry, D.A., Rocha, H.A.O., Franco, C.R.C., Chammas, R., Gillies, R.J. and Trindade, E.S. (2020). Green does not always mean go: a sulfated galactan from Codium isthmocladum green seaweed reduces melanoma metastasis through direct regulation of malignancy features. Carbohydrate Polymers, 250 116869, 116869. doi: 10.1016/j.carbpol.2020.116869

Beyond gold nanoparticles cytotoxicity: potential to impair metastasis hallmarks

Pendiuk Gonçalves, Jenifer, Fraga da Cruz, Anderson, Ribeiro de Barros, Heloise, Santana Borges, Beatriz, Almeida Soares de Medeiros, Lia Carolina, Soares, Maurilio José, Padovan dos Santos, Mayara, Grassi, Marco Tadeu, Chandra, Anil, del Mercato, Loretta Laureana, Rodrigues Rossi, Gustavo, da Silva Trindade, Edvaldo, Riegel-Vidotti, Izabel Cristina and Camargo de Oliveira, Carolina (2020). Beyond gold nanoparticles cytotoxicity: potential to impair metastasis hallmarks. European Journal of Pharmaceutics and Biopharmaceutics, 157, 221-232. doi: 10.1016/j.ejpb.2020.10.019

The antitumor effect of heparin is not mediated by direct NK cell activation

Rossi, Gustavo R., Gonçalves, Jenifer P., McCulloch, Timothy, Delconte, Rebecca B., Hennessy, Robert J., Huntington, Nicholas D., Trindade, Edvaldo S. and Souza-Fonseca-Guimaraes, Fernando (2020). The antitumor effect of heparin is not mediated by direct NK cell activation. Journal of Clinical Medicine, 9 (8) 2666, 2666-11. doi: 10.3390/jcm9082666

Tumor microenvironment-associated extracellular matrix components regulate NK cell function

Rossi, Gustavo Rodrigues, Trindade, Edvaldo S. and Souza-Fonseca-Guimaraes, Fernando (2020). Tumor microenvironment-associated extracellular matrix components regulate NK cell function. Frontiers in Immunology, 11 73, 73. doi: 10.3389/fimmu.2020.00073

Non-cytotoxic sulfated heterorhamnan from Gayralia brasiliensis green seaweed reduces driver features of melanoma metastatic progression

Bellan, D. L., Mazepa, E., Biscaia, S. M. P., Gonçalves, J. P., Oliveira, C. C., Rossi, G. R., Ferreira, L. G., Noseda, M. D., Trindade, E. S., Duarte, M. E. R. and Franco, C. R. C. (2020). Non-cytotoxic sulfated heterorhamnan from Gayralia brasiliensis green seaweed reduces driver features of melanoma metastatic progression. Marine Biotechnology, 22 (2), 194-206. doi: 10.1007/s10126-020-09944-9

Preparation and characterization of 4-nitrochalcone-folic acid-poly(methyl methacrylate) nanocapsules and cytotoxic activity on HeLa and NIH3T3 cells

Carpio Arévalo, Juan Marcelo, Feuser, Paulo Emilio, Rossi, Gustavo Rodrigues, Trindade, Edvaldo S., da Silva Córneo, Emily, Machado-de-Ávila, Ricardo Andrez, Sayer, Claudia, Cadena, Silvia Maria Suter C., Noleto, Guilhermina Rodrigues, Martinez, Glaucia Regina, Hermes de Araújo, Pedro H. and Merlin Rocha, Maria Eliane (2019). Preparation and characterization of 4-nitrochalcone-folic acid-poly(methyl methacrylate) nanocapsules and cytotoxic activity on HeLa and NIH3T3 cells. Journal of Drug Delivery Science and Technology, 54 101300, 101300. doi: 10.1016/j.jddst.2019.101300

Microscopic analysis of colonization of Colletotrichum abscissum in citrus tissues

Savi, Daiani Cristina, Rossi, Bruno Janoski, Rossi, Gustavo Rodrigues, Ferreira-Maba, Lisandra Santos, Bini, Israel Henrique, Trindade, Edvaldo da Silva, Goulin, Eduardo Henrique, Machado, Marcos Antonio and Glienke, Chirlei (2019). Microscopic analysis of colonization of Colletotrichum abscissum in citrus tissues. Microbiological Research, 226, 27-33. doi: 10.1016/j.micres.2019.05.005

Loss-of-Function in SMAD4 Might Not Be Critical for Human Natural Killer Cell Responsiveness to TGF-β

Healy, Lachlan P., Rossi, Gustavo R., Rautela, Jai, Slade, Charlotte A., Huntington, Nicholas D., Winship, Ingrid M. and Souza-Fonseca-Guimaraes, Fernando (2019). Loss-of-Function in SMAD4 Might Not Be Critical for Human Natural Killer Cell Responsiveness to TGF-β. Frontiers in Immunology, 10 (MAY) 904. doi: 10.3389/fimmu.2019.00904

In vitro attenuation of classic metastatic melanoma-related features by highly diluted natural complexes: molecular and functional analyses

Gonçalves, Jenifer Pendiuk, Potrich, Francine Bittencourt, Dos Santos, Maria Luiza Ferreira, Gagosian, Viviana Stephanie Costa, Rossi, Gustavo Rodrigues, Thiago, Jacomasso, Mendes, Aline, Nader, Helena Bonciani, Winnischofer, Sheila Maria Brochado, Trindade, Edvaldo S. and De Oliveira, Carolina Camargo (2019). In vitro attenuation of classic metastatic melanoma-related features by highly diluted natural complexes: molecular and functional analyses. International Journal of Oncology, 55 (3), 721-732. doi: 10.3892/ijo.2019.4846

Viscera of fishes as raw material for extraction of glycosaminoglycans of pharmacological interest

Nogueira, Alexsandro V., Rossi, Gustavo R., Iacomini, Marcello, Sassaki, Guilherme L., Trindade, Edvaldo S. and Cipriani, Thales R. (2019). Viscera of fishes as raw material for extraction of glycosaminoglycans of pharmacological interest. International Journal of Biological Macromolecules, 121, 239-248. doi: 10.1016/j.ijbiomac.2018.09.156

Monoclonal antibody DL11C8 identifies ADAM23 as a component of lipid raft microdomains

Borgonovo, Zaine L. M., Ribeiro, Caroline F., Costa, Michele D. M., Souza, Ingrid L. M., Rossi, Gustavo R., Alcantara, Monica V., Ingberman, Max, Braga, Luciano G., Mercadante, Adriana F., Nakao, Lia S. and Zanata, Silvio M. (2018). Monoclonal antibody DL11C8 identifies ADAM23 as a component of lipid raft microdomains. Neuroscience, 384, 165-177. doi: 10.1016/j.neuroscience.2018.05.016

A low-molecular-weight galactofucan from the seaweed, Spatoglossum schröederi, binds fibronectin and inhibits capillary-like tube formation in vitro

Menezes, Maira Maria, Nobre, Leonardo Thiago Duarte Barreto, Rossi, Gustavo Rodrigues, Almeida-Lima, Jailma, Melo-Silveira, Raniere Fagundes, Franco, Celia Regina Cavichiolo, Trindade, Edvaldo Silva, Nader, Helena Bonciani and Rocha, Hugo Alexandre Oliveira (2018). A low-molecular-weight galactofucan from the seaweed, Spatoglossum schröederi, binds fibronectin and inhibits capillary-like tube formation in vitro. International Journal of Biological Macromolecules, 111, 1067-1075. doi: 10.1016/j.ijbiomac.2018.01.119

Safe therapeutics of murine melanoma model using a novel antineoplasic, the partially methylated mannogalactan from Pleurotus eryngii

Biscaia, S. M.P., Carbonero, E. R., Bellan, D. L., Borges, B. S., Costa, C. R., Rossi, G. R., Gonçalves, J. P., Melo, C. M., Lívero, F. A.R., Ruthes, A. C., Zotz, R., Silva, E. V., Oliveira, C. C., Acco, A., Nader, H. B., Chammas, R., Iacomini, M., Franco, C. R.C. and Trindade, E. S. (2017). Safe therapeutics of murine melanoma model using a novel antineoplasic, the partially methylated mannogalactan from Pleurotus eryngii. Carbohydrate Polymers, 178, 95-104. doi: 10.1016/j.carbpol.2017.08.117

Increased cellular uptake of lauryl gallate loaded in superparamagnetic poly(methyl methacrylate) nanoparticles due to surface modification with folic acid

Feuser, Paulo Emilio, Arévalo, Juan Marcelo Carpio, Junior, Enio Lima, Rossi, Gustavo Rodrigues, da Silva Trindade, Edvaldo, Rocha, Maria Eliane Merlin, Jacques, Amanda Virtuoso, Ricci-Júnior, Eduardo, Santos-Silva, Maria Claudia, Sayer, Claudia and de Araújo, Pedro H. Hermes (2016). Increased cellular uptake of lauryl gallate loaded in superparamagnetic poly(methyl methacrylate) nanoparticles due to surface modification with folic acid. Journal of Materials Science: Materials in Medicine, 27 (12) 185. doi: 10.1007/s10856-016-5796-0

Effect of pegylated phosphatidylserine-containing liposomes in experimental chronic arthritis

Urbano, Paulo C.M., Soccol, Vanete T., Teixeira, Vivian N., Oliveira, Patrícia G., Filippin, Lidiane I., Bonat, Wagner H., de Oliveira, Carolina, Rossi, Gustavo R., Xavier, Ricardo M. and Azevedo, Valderilio F. (2015). Effect of pegylated phosphatidylserine-containing liposomes in experimental chronic arthritis. BMC Pharmacology and Toxicology, 16 (1) 24. doi: 10.1186/s40360-015-0022-0

TIGIT limits anti-bacterial immunity and is a potential target for immunotherapy

Souza-Fonseca-Guimaraes, Fernando, Rossi, Gustavo Rodrigues, Wells, Timothy and McCulloch, Timothy Ryan (2023). TIGIT limits anti-bacterial immunity and is a potential target for immunotherapy. IMMUNOLOGY2023™ Meeting, Washington, DC, United States, 11 - 15 May 2023. Rockville, MD, United States: The American Association of Immunologists. doi: 10.4049/jimmunol.210.supp.64.14