The University of Queensland

Assessment of gene function of mouse innate lymphoid cells for in vivo analysis using retroviral transduction

Seillet, Cyril and Belz, Gabrielle T. (2019). Assessment of gene function of mouse innate lymphoid cells for in vivo analysis using retroviral transduction. Target identification and validation in drug discovery: methods and protocols. (pp. 231-240) edited by Jürgen Moll and Sebastian Carotta. New York, NY USA: Humana Press. doi: 10.1007/978-1-4939-9145-7_14

Innate lymphoid cells type 3

Belz, Gabrielle T., Rankin, Lucille C., Carotta, Sebastian, Romagnani, Chiara and Huntington, Nicholas D. (2016). Innate lymphoid cells type 3. Encyclopedia of Immunobiology. (pp. 156-168) edited by Michael J.H. Ratcliffe. Cambridge, MA, United States: Academic Press. doi: 10.1016/B978-0-12-374279-7.04004-2

Cytotoxic T lymphocytes and natural killer cells

Nutt, Stephen L., Carotta, Sebastian, Kallies, Axel and Belz, Gabrielle T. (2013). Cytotoxic T lymphocytes and natural killer cells. Clinical immunology: principles and practice: fourth edition. (pp. 215-227) Amsterdam, Netherlands: Elsevier Inc.. doi: 10.1016/B978-0-7234-3691-1.00015-5

Terminal differentiation of dendritic cells

Seillet, Cyril and Belz, Gabrielle T. (2013). Terminal differentiation of dendritic cells. Development and Function of Myeloid Subsets. (pp. 185-210) edited by Kenneth M. Murphy and Miriam Merad. Maryland Heights, MO, United States: Academic Press. doi: 10.1016/B978-0-12-417028-5.00007-7

Abstract 2698: TCF-1 is a critical regulator of intraepithelial lymphocytes in colorectal carcinoma

Yakou, Marina H., Ghilas, Sonia, Tran, Kelly, Liao, Yang, Afshar-Sterle, Shoukat, Kumari, Anita, Schmid, Kevin, Dijkstra, Christine, Inguanti, Chantelle, Ostrouska, Simone, Wilcox, Jordan, Smith, Maxine, Parathan, Pavitha, Allam, Amr, Xue, Hai-Hui, Belz, Gabrielle T., Mariadason, John M., Behren, Andreas, Drummond, Grant R., Ruscher, Roland, Williams, David S., Pal, Bhupinder, Shi, Wei, Ernst, Matthias, Raghu, Dinesh and Mielke, Lisa A. (2024). Abstract 2698: TCF-1 is a critical regulator of intraepithelial lymphocytes in colorectal carcinoma. Cancer Research, 84 (6_Supplement), 2698-2698. doi: 10.1158/1538-7445.am2024-2698

The transcription factor <scp>SpiB</scp> regulates the fibroblastic reticular cell network and <scp>CD8</scp>⁺ T‐cell responses in lymph nodes

Horsnell, Harry L, Cao, Wang HJ, Belz, Gabrielle T, Mueller, Scott N and Alexandre, Yannick O (2024). The transcription factor SpiB regulates the fibroblastic reticular cell network and CD8+ T‐cell responses in lymph nodes. Immunology & Cell Biology, 102 (4), 269-279. doi: 10.1111/imcb.12740

In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection

Tan, Chin Wee, Chen, Jinjin, Liu, Ning, Bhuva, Dharmesh D., Blick, Tony, Monkman, James, Cooper, Caroline, Kharbanda, Malvika, Feher, Kristen, Phipson, Belinda, Killingbeck, Emily E., Pan, Liuliu, Kim, Youngmi, Liang, Yan, Nam, Andy, Leon, Michael, Souza-Fonseca-Guimaraes, Paulo, Nagashima, Seigo, Camargo Martins, Ana Paula, Machado-Souza, Cleber, de Noronha, Lucia, Tang, Benjamin, Short, Kirsty, Fraser, John, Belz, Gabrielle T., Souza-Fonseca-Guimaraes, Fernando, Kulasinghe, Arutha and Davis, Melissa J. (2024). In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection. eBioMedicine, 101 105016, 105016. doi: 10.1016/j.ebiom.2024.105016

PD-1 regulates ILC3-driven intestinal immunity and homeostasis

Jacquelot, Nicolas, Xiong, Le, Cao, Wang H.J., Huang, Qiutong, Yu, Huiyang, Sayad, Azin, Anttila, Casey J.A., Baldwin, Tracey M., Hickey, Peter F., Amann-Zalcenstein, Daniela, Ohashi, Pamela S., Nutt, Stephen L., Belz, Gabrielle T. and Seillet, Cyril (2024). PD-1 regulates ILC3-driven intestinal immunity and homeostasis. Mucosal Immunology. doi: 10.1016/j.mucimm.2024.03.002

Faecal microbial transfer and complex carbohydrates mediate protection against COPD

Budden, Kurtis F, Shukla, Shakti D, Bowerman, Kate L, Vaughan, Annalicia, Gellatly, Shaan L, Wood, David L A, Lachner, Nancy, Idrees, Sobia, Rehman, Saima Firdous, Faiz, Alen, Patel, Vyoma K, Donovan, Chantal, Alemao, Charlotte A, Shen, Sj, Amorim, Nadia, Majumder, Rajib, Vanka, Kanth S, Mason, Jazz, Haw, Tatt Jhong, Tillet, Bree, Fricker, Michael, Keely, Simon, Hansbro, Nicole, Belz, Gabrielle T, Horvat, Jay, Ashhurst, Thomas, van Vreden, Caryn, McGuire, Helen, Fazekas de St Groth, Barbara ... Hansbro, Philip M (2024). Faecal microbial transfer and complex carbohydrates mediate protection against COPD. Gut, gutjnl-2023. doi: 10.1136/gutjnl-2023-330521

Faster Gastrointestinal Transit, Reduced Small Intestinal Smooth Muscle Tone and Dysmotility in the Nlgn3R451C Mouse Model of Autism

Hosie, Suzanne, Abo-Shaban, Tanya, Mou, Kevin, Balasuriya, Gayathri K., Mohsenipour, Mitra, Alamoudi, Mohammed U., Filippone, Rhiannon T., Belz, Gabrielle T., Franks, Ashley E., Bornstein, Joel C., Nurgali, Kulmira and Hill-Yardin, Elisa L. (2024). Faster Gastrointestinal Transit, Reduced Small Intestinal Smooth Muscle Tone and Dysmotility in the Nlgn3R451C Mouse Model of Autism. International Journal of Molecular Sciences, 25 (2) 832, 832. doi: 10.3390/ijms25020832

Unraveling the diversity and functions of tissue-resident plasma cells

Tellier, Julie, Tarasova, Ilariya, Nie, Junli, Smillie, Christopher S., Fedele, Pasquale L., Cao, Wang H. J., Groom, Joanna R., Belz, Gabrielle T., Bhattacharya, Deepta, Smyth, Gordon K. and Nutt, Stephen L. (2024). Unraveling the diversity and functions of tissue-resident plasma cells. Nature Immunology, 25 (2), 330-342. doi: 10.1038/s41590-023-01712-w

Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures

Stylianou, Nataly, Sebina, Ismail, Matigian, Nicholas, Monkman, James, Doehler, Hadeel, Röhl, Joan, Allenby, Mark, Nam, Andy, Pan, Liuliu, Rockstroh, Anja, Sadeghirad, Habib, Chung, Kimberly, Sobanski, Thais, O'Byrne, Ken, Almeida, Ana Clara Simoes Florido, Rebutini, Patricia Zadorosnei, Machado‐Souza, Cleber, Stonoga, Emanuele Therezinha Schueda, Warkiani, Majid E, Salomon, Carlos, Short, Kirsty, McClements, Lana, de Noronha, Lucia, Huang, Ruby, Belz, Gabrielle T, Souza‐Fonseca‐Guimaraes, Fernando, Clifton, Vicki and Kulasinghe, Arutha (2024). Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures. Clinical & Translational Immunology, 13 (2) e1488, e1488. doi: 10.1002/cti2.1488

A centenary of service: 100 years of <i>Immunology &amp; Cell Biology</i>

Liston, Adrian, La Flamme, Anne C, Belz, Gabrielle T, Parish, Christopher R and Greer, Judith M (2023). A centenary of service: 100 years of Immunology & Cell Biology. Immunology & Cell Biology, 101 (10), 882-890. doi: 10.1111/imcb.12700

Survival and division fate programs are preserved but retuned during the naïve to memory CD8⁺ T‐cell transition

Heinzel, Susanne, Cheon, HoChan, Belz, Gabrielle T and Hodgkin, Philip D (2023). Survival and division fate programs are preserved but retuned during the naïve to memory CD8+ T‐cell transition. Immunology & Cell Biology, 102 (1), 46-57. doi: 10.1111/imcb.12699

TCF-1 limits intraepithelial lymphocyte antitumor immunity in colorectal carcinoma

Yakou, Marina H., Ghilas, Sonia, Tran, Kelly, Liao, Yang, Afshar-Sterle, Shoukat, Kumari, Anita, Schmid, Kevin, Dijkstra, Christine, Inguanti, Chantelle, Ostrouska, Simone, Wilcox, Jordan, Smith, Maxine, Parathan, Pavitha, Allam, Amr, Xue, Hai-Hui, Belz, Gabrielle T., Mariadason, John M., Behren, Andreas, Drummond, Grant R., Ruscher, Roland, Williams, David S., Pal, Bhupinder, Shi, Wei, Ernst, Matthias, Raghu, Dinesh and Mielke, Lisa A. (2023). TCF-1 limits intraepithelial lymphocyte antitumor immunity in colorectal carcinoma. Science Immunology, 8 (88) ARTN eadf2163, eadf2163. doi: 10.1126/sciimmunol.adf2163

A robust platform for integrative spatial multi‐omics analysis to map immune responses to SARS‐CoV‐2 infection in lung tissues

Tan, Xiao, Grice, Laura F., Tran, Minh, Mulay, Onkar, Monkman, James, Blick, Tony, Vo, Tuan, Almeida, Ana Clara, da Silva Motta, Jarbas, Fernandes de Moura, Karen, Machado‐Souza, Cleber, Souza‐Fonseca‐Guimaraes, Paulo, Baena, Cristina Pellegrino, de Noronha, Lucia, Guimaraes, Fernanda Simoes Fortes, Luu, Hung N., Drennon, Tingsheng, Williams, Stephen, Stern, Jacob, Uytingco, Cedric, Pan, Liuliu, Nam, Andy, Cooper, Caroline, Short, Kirsty, Belz, Gabrielle T., Souza‐Fonseca‐Guimaraes, Fernando, Kulasinghe, Arutha and Nguyen, Quan (2023). A robust platform for integrative spatial multi‐omics analysis to map immune responses to SARS‐CoV‐2 infection in lung tissues. Immunology, 170 (3), 401-418. doi: 10.1111/imm.13679

The seductive allure of spatial biology: accelerating new discoveries in the life sciences

Kulasinghe, Arutha, Wood, Fiona and Belz, Gabrielle (2023). The seductive allure of spatial biology: accelerating new discoveries in the life sciences. Immunology & Cell Biology, 101 (9), 798-804. doi: 10.1111/imcb.12669

Innate lymphoid cells: potential targets for cancer therapeutics

Ng, Chun Ki and Belz, Gabrielle T. (2023). Innate lymphoid cells: potential targets for cancer therapeutics. Trends in Cancer, 9 (2), 158-171. doi: 10.1016/j.trecan.2022.10.007

IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study

Shojaei, Maryam, Shamshirian, Amir, Monkman, James, Grice, Laura, Tran, Minh, Tan, Chin Wee, Teo, Siok Min, Rodrigues Rossi, Gustavo, McCulloch, Timothy R., Nalos, Marek, Raei, Maedeh, Razavi, Alireza, Ghasemian, Roya, Gheibi, Mobina, Roozbeh, Fatemeh, Sly, Peter D., Spann, Kirsten M., Chew, Keng Yih, Zhu, Yanshan, Xia, Yao, Wells, Timothy J., Senegaglia, Alexandra Cristina, Kuniyoshi, Carmen Lúcia, Franck, Claudio Luciano, dos Santos, Anna Flavia Ribeiro, Noronha, Lucia de, Motamen, Sepideh, Valadan, Reza, Amjadi, Omolbanin ... Tang, Benjamin (2023). IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study. Frontiers in Immunology, 13 1060438, 1-14. doi: 10.3389/fimmu.2022.1060438

Author Correction: CIS is a potent checkpoint in NK cell–mediated tumor immunity (Nature Immunology, (2016), 17, 7, (816-824), 10.1038/ni.3470)

Delconte, Rebecca B., Kolesnik, Tatiana B., Dagley, Laura F., Rautela, Jai, Shi, Wei, Putz, Eva M., Stannard, Kimberley, Zhang, Jian-Guo, Teh, Charis, Firth, Matt, Ushiki, Takashi, Andoniou, Christopher E., Degli-Esposti, Mariapia A., Sharp, Phillip P., Sanvitale, Caroline E., Infusini, Giuseppe, Liau, Nicholas P. D., Linossi, Edmond M., Burns, Christopher J., Carotta, Sebastian, Gray, Daniel H. D., Seillet, Cyril, Hutchinson, Dana S., Belz, Gabrielle T., Webb, Andrew I., Alexander, Warren S., Li, Shawn S., Bullock, Alex N., Babon, Jeffrey J. ... Huntington, Nicholas D. (2023). Author Correction: CIS is a potent checkpoint in NK cell–mediated tumor immunity (Nature Immunology, (2016), 17, 7, (816-824), 10.1038/ni.3470). Nature Immunology, 25 (2), 371-372. doi: 10.1038/s41590-023-01714-8

Gutsy sensations modulate intestinal disease

Cao, Wang and Belz, Gabrielle (2023). Gutsy sensations modulate intestinal disease. Trends in Immunology, 44 (1), 1-3. doi: 10.1016/j.it.2022.11.007

Metabolic features of innate lymphoid cells

Yu, Huiyang, Jacquelot, Nicolas and Belz, Gabrielle T. (2022). Metabolic features of innate lymphoid cells. Journal of Experimental Medicine, 219 (11) e20221140. doi: 10.1084/jem.20221140

A protocol to isolate bone marrow innate lymphoid cells for alymphoid mouse reconstitution

Jacquelot, Nicolas, Huang, Qiutong, Belz, Gabrielle T. and Seillet, Cyril (2022). A protocol to isolate bone marrow innate lymphoid cells for alymphoid mouse reconstitution. STAR Protocols, 3 (3) 101534, 1-19. doi: 10.1016/j.xpro.2022.101534

Transcriptomic profiling of cardiac tissues from SARS‐CoV ‐2 patients identifies DNA damage

Kulasinghe, Arutha, Liu, Ning, Tan, Chin Wee, Monkman, James, Sinclair, Jane E., Bhuva, Dharmesh D., Godbolt, David, Pan, Liuliu, Nam, Andy, Sadeghirad, Habib, Sato, Kei, Bassi, Gianluigi Li, O'Byrne, Ken, Hartmann, Camila, Miggiolaro, Anna Flavia Ribeiro dos Santos, Marques, Gustavo Lenci, Moura, Lidia Zytynski, Richard, Derek, Adams, Mark, Noronha, Lucia de, Baena, Cristina Pellegrino, Suen, Jacky Y., Arora, Rakesh, Belz, Gabrielle T., Short, Kirsty R., Davis, Melissa J., Souza‐Fonseca Guimaraes, Fernando and Fraser, John F. (2022). Transcriptomic profiling of cardiac tissues from SARS‐CoV ‐2 patients identifies DNA damage. Immunology, 168 (3), 403-419. doi: 10.1111/imm.13577

ZBTB46 in ILC3: shared transcriptional infrastructure defines gut-protective capabilities

Curio, Sophie and Belz, Gabrielle T. (2022). ZBTB46 in ILC3: shared transcriptional infrastructure defines gut-protective capabilities. Trends in Immunology, 43 (9), 690-692. doi: 10.1016/j.it.2022.07.008

CIS and TGF ‐β regulatory pathways influence immunity to bacterial infection

McCulloch, Timothy R., Rossi, Gustavo R., Schreuder, Jaring, Belz, Gabrielle T., Wells, Timothy J. and Souza‐Fonseca‐Guimaraes, Fernando (2022). CIS and TGF ‐β regulatory pathways influence immunity to bacterial infection. Immunology, 167 (1), 54-63. doi: 10.1111/imm.13516

Caspase-8 has dual roles in regulatory T cell homeostasis balancing immunity to infection and collateral inflammatory damage

Teh, Charis E., Preston, Simon P., Robbins, Alissa K., Stutz, Michael D., Cooney, James, Clark, Michelle P., Policheni, Antonia N., Allison, Cody C., Mackiewicz, Liana, Arandjelovic, Philip, Ebert, Gregor, Doerflinger, Marcel, Tan, Tania, Rankin, Lucille C., Teh, Peggy P., Belz, Gabrielle T., Kallies, Axel, Strasser, Andreas, Pellegrini, Marc and Gray, Daniel H D (2022). Caspase-8 has dual roles in regulatory T cell homeostasis balancing immunity to infection and collateral inflammatory damage. Science Immunology, 7 (69) eabn8041. doi: 10.1126/sciimmunol.abn8041

Innate lymphoid cells and cancer

Jacquelot, Nicolas, Seillet, Cyril, Vivier, Eric and Belz, Gabrielle T. (2022). Innate lymphoid cells and cancer. Nature Immunology, 23 (3), 371-379. doi: 10.1038/s41590-022-01127-z

A diverse fibroblastic stromal cell landscape in the spleen directs tissue homeostasis and immunity

Alexandre, Yannick O., Schienstock, Dominik, Lee, Hyun Jae, Gandolfo, Luke C., Williams, Cameron G., Devi, Sapna, Pal, Bhupinder, Groom, Joanna R., Cao, Wang, Christo, Susan N., Gordon, Claire L., Starkey, Graham, D’Costa, Rohit, Mackay, Laura K., Haque, Ashraful, Ludewig, Burkhard, Belz, Gabrielle T. and Mueller, Scott N. (2022). A diverse fibroblastic stromal cell landscape in the spleen directs tissue homeostasis and immunity. Science Immunology, 7 (67) eabj0641, eabj0641. doi: 10.1126/sciimmunol.abj0641

Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signatures

Kulasinghe, Arutha, Tan, Chin Wee, dos Santos Miggiolaro, Anna Flavia Ribeiro, Monkman, James, SadeghiRad, Habib, Bhuva, Dharmesh D., da Silva Motta Junior, Jarbas, Vaz de Paula, Caroline Busatta, Nagashima, Seigo, Baena, Cristina Pellegrino, Souza-Fonseca-Guimaraes, Paulo, de Noronha, Lucia, McCulloch, Timothy, Rodrigues Rossi, Gustavo, Cooper, Caroline, Tang, Benjamin, Short, Kirsty R., Davis, Melissa J., Souza-Fonseca-Guimaraes, Fernando, Belz, Gabrielle T. and O'Byrne, Ken (2022). Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signatures. European Respiratory Journal, 59 (6) 2101881, 1-19. doi: 10.1183/13993003.01881-2021

The unique role of innate lymphoid cells in cancer and the hepatic microenvironment

Curio, Sophie and Belz, Gabrielle T. (2022). The unique role of innate lymphoid cells in cancer and the hepatic microenvironment. Cellular and Molecular Immunology, 19 (9), 1012-1029. doi: 10.1038/s41423-022-00901-1

Metastasis-entrained eosinophils enhance lymphocyte-mediated anti-tumor immunity

Grisaru-Tal, Sharon, Dulberg, Shai, Beck, Lir, Zhang, Chunyan, Itan, Michal, Hediyeh-zadeh, Soroor, Caldwell, Julie, Rozenberg, Perri, Dolitzky, Avishay, Avlas, Shmuel, Hazut, Inbal, Gordon, Yaara, Shani, Ophir, Tsuriel, Shlomo, Gerlic, Motti, Erez, Neta, Jacquelot, Nicolas, Belz, Gabrielle, Rothenberg, Marc E, Davis, Melissa J, Yu, Hua, Geiger, Tamar, Madi, Asaf and Munitz, Ariel (2021). Metastasis-entrained eosinophils enhance lymphocyte-mediated anti-tumor immunity. Cancer Research, 81 (21), 5555-5571. doi: 10.1158/0008-5472.can-21-0839

Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity

Christo, Susan N., Evrard, Maximilien, Park, Simone L., Gandolfo, Luke C., Burn, Thomas N., Fonseca, Raissa, Newman, Dane M., Alexandre, Yannick O., Collins, Nicholas, Zamudio, Natasha M., Souza-Fonseca-Guimaraes, Fernando, Pellicci, Daniel G., Chisanga, David, Shi, Wei, Bartholin, Laurent, Belz, Gabrielle T., Huntington, Nicholas D., Lucas, Andrew, Lucas, Michaela, Mueller, Scott N., Heath, William R., Ginhoux, Florent, Speed, Terence P., Carbone, Francis R., Kallies, Axel and Mackay, Laura K. (2021). Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity. Nature Immunology, 22 (9), 1140-1151. doi: 10.1038/s41590-021-01004-1

Natural killer cells and type 1 innate lymphoid cells in hepatocellular carcinoma: current knowledge and future perspectives

Jacquelot, Nicolas, Seillet, Cyril, Souza-Fonseca-Guimaraes, Fernando, Sacher, Adrian G, Belz, Gabrielle T and Ohashi, Pamela S (2021). Natural killer cells and type 1 innate lymphoid cells in hepatocellular carcinoma: current knowledge and future perspectives. International Journal of Molecular Sciences, 22 (16) 9044, 1-32. doi: 10.3390/ijms22169044

Host IL11 signaling suppresses CD4+ T cell-mediated antitumor responses to colon cancer in mice

Huynh, Jennifer, Baloyan, David, Chisanga, David, Shi, Wei, O'Brien, Megan, Afshar-Sterle, Shoukat, Alorro, Mariah, Pang, Lokman, Williams, David S., Parslow, Adam C., Thilakasiri, Pathum, Eissmann, Moritz F., Boon, Louis, Masson, Frederick, Chand, Ashwini L. and Ernst, Matthias (2021). Host IL11 signaling suppresses CD4+ T cell-mediated antitumor responses to colon cancer in mice. Cancer Immunology Research, 9 (7), 735-747. doi: 10.1158/2326-6066.CIR-19-1023

Differences in pulmonary group 2 innate lymphoid cells are dependent on mouse age, sex and strain

Loering, Svenja, Cameron, Guy J. M., Bhatt, Nirmal P., Belz, Gabrielle T., Foster, Paul S., Hansbro, Philip M. and Starkey, Malcolm R. (2021). Differences in pulmonary group 2 innate lymphoid cells are dependent on mouse age, sex and strain. Immunology and Cell Biology, 99 (5), 542-551. doi: 10.1111/imcb.12430

Intestinal-derived ILCs migrating in lymph increase IFNγ production in response to Salmonella Typhimurium infection

Kästele, Verena, Mayer, Johannes, Lee, Edward S., Papazian, Natalie, Cole, John J., Cerovic, Vuk, Belz, Gabrielle, Tomura, Michio, Eberl, Gerard, Goodyear, Carl, Maciewicz, Rose A., Wall, Daniel, Cupedo, Tom, Withers, David R. and Milling, Simon (2021). Intestinal-derived ILCs migrating in lymph increase IFNγ production in response to Salmonella Typhimurium infection. Mucosal Immunology, 14 (3), 717-727. doi: 10.1038/s41385-020-00366-3

Unleashing ILC2-dependent anti-tumor immunity to melanoma

Belz, Gabrielle T and Jacquelot, Nicolas (2021). Unleashing ILC2-dependent anti-tumor immunity to melanoma. The Journal of Immunology, 206 (1_Supplement), 57.05-57.05. doi: 10.4049/jimmunol.206.supp.57.05

Neuroimmune interactions and rhythmic regulation of innate lymphoid cells

Jacquelot, Nicolas, Belz, Gabrielle T. and Seillet, Cyril (2021). Neuroimmune interactions and rhythmic regulation of innate lymphoid cells. Frontiers in Neuroscience, 15 657081, 1-8. doi: 10.3389/fnins.2021.657081

Absence of Batf3 reveals a new dimension of cell state heterogeneity within conventional dendritic cells

Lukowski, Samuel W., Rodahl, Inga, Kelly, Samuel, Yu, Meihua, Gotley, James, Zhou, Chenhao, Millard, Susan, Andersen, Stacey B., Christ, Angelika N., Belz, Gabrielle, Frazer, Ian H. and Chandra, Janin (2021). Absence of Batf3 reveals a new dimension of cell state heterogeneity within conventional dendritic cells. iScience, 24 (5) 102402, 1-21. doi: 10.1016/j.isci.2021.102402

Tertiary lymphoid structures and B lymphocytes in cancer prognosis and response to immunotherapies

Jacquelot, N., Tellier, J., Nutt, S.l. and Belz, G.T. (2021). Tertiary lymphoid structures and B lymphocytes in cancer prognosis and response to immunotherapies. OncoImmunology, 10 (1) 1900508, 1900508. doi: 10.1080/2162402x.2021.1900508

Type 2 innate lymphoid cells protect against colorectal cancer progression and predict improved patient survival

Huang, Qiutong, Jacquelot, Nicolas, Preaudet, Adele, Hediyeh-zadeh, Soroor, Souza-Fonseca-Guimaraes, Fernando, McKenzie, Andrew N. J., Hansbro, Philip M., Davis, Melissa J., Mielke, Lisa A., Putoczki, Tracy L. and Belz, Gabrielle T. (2021). Type 2 innate lymphoid cells protect against colorectal cancer progression and predict improved patient survival. Cancers, 13 (3) 559, 559-16. doi: 10.3390/cancers13030559

Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma

Jacquelot, Nicolas, Seillet, Cyril, Wang, Minyu, Pizzolla, Angela, Liao, Yang, Hediyeh-zadeh, Soroor, Grisaru-Tal, Sharon, Louis, Cynthia, Huang, Qiutong, Schreuder, Jaring, Souza-Fonseca-Guimaraes, Fernando, de Graaf, Carolyn A., Thia, Kevin, Macdonald, Sean, Camilleri, Mary, Luong, Kylie, Zhang, Shengbo, Chopin, Michael, Molden-Hauer, Tristan, Nutt, Stephen L., Umansky, Viktor, Ciric, Bogoljub, Groom, Joanna R., Foster, Paul S., Hansbro, Philip M., McKenzie, Andrew N. J., Gray, Daniel H. D., Behren, Andreas, Cebon, Jonathan ... Belz, Gabrielle T. (2021). Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma. Nature Immunology, 22 (7), 851-864. doi: 10.1038/s41590-021-00943-z

T-helper 22 cells develop as a distinct lineage from Th17 cells during bacterial infection and phenotypic stability is regulated by T-bet

Barnes, Jessica L., Plank, Maximilian W., Asquith, Kelly, Maltby, Steven, Sabino, Lorena R., Kaiko, Gerard E., Lochrin, Alyssa, Horvat, Jay C., Mayall, Jemma R., Kim, Richard Y., Hansbro, Philip M., Keely, Simon, Belz, Gabrielle T., Tay, Hock L. and Foster, Paul S. (2021). T-helper 22 cells develop as a distinct lineage from Th17 cells during bacterial infection and phenotypic stability is regulated by T-bet. Mucosal Immunology, 14 (5), 1077-1087. doi: 10.1038/s41385-021-00414-6

Type 2 innate lymphoid cells: a novel actor in anti-melanoma immunity

Jacquelot, Nicolas and Belz, Gabrielle T. (2021). Type 2 innate lymphoid cells: a novel actor in anti-melanoma immunity. OncoImmunology, 10 (1) 1943168, 1943168. doi: 10.1080/2162402x.2021.1943168

Increased lipid metabolism impairs NK cell function and mediates adaptation to the lymphoma environment

Kobayashi, Takumi, Lam, Pui Yeng, Jiang, Hui, Bednarska, Karolina, Gloury, Renee Elyse, Murigneux, Valentine, Tay, Joshua, Jacquelot, Nicolas, Li, Rui, Tuong, Zewen Kelvin, Leggatt, Graham, Gandhi, Maher K., Hill, Michelle M, Belz, Gabrielle T., Ngo, Shyuan, Kallies, Axel and Mattarollo, Stephen R. (2020). Increased lipid metabolism impairs NK cell function and mediates adaptation to the lymphoma environment. Blood, 136 (26), 3004-3017. doi: 10.1182/blood.2020005602

Impact of diet and the bacterial microbiome on the mucous barrier and immune disorders

Alemao, Charlotte A., Budden, Kurtis F., Gomez, Henry M., Rehman, Saima F., Marshall, Jacqueline E., Shukla, Shakti D., Donovan, Chantal, Forster, Samuel C., Yang, Ian A., Keely, Simon, Mann, Elizabeth R., El Omar, Emad M., Belz, Gabrielle T. and Hansbro, Philip M. (2020). Impact of diet and the bacterial microbiome on the mucous barrier and immune disorders. Allergy, 76 (3) all.14548, 1-21. doi: 10.1111/all.14548

Systemic administration of IL‐33 induces a population of circulating KLRG1 hi type 2 innate lymphoid cells and inhibits type 1 innate immunity against multiple myeloma

Guillerey, Camille, Stannard, Kimberley, Chen, Jason, Krumeich, Sophie, Miles, Kim, Nakamura, Kyohei, Smith, Jessica, Yu, Yuan, Ng, Susanna, Harjunpää, Heidi, Teng, Michele W. L., Engwerda, Christian, Belz, Gabrielle T. and Smyth, Mark J. (2020). Systemic administration of IL‐33 induces a population of circulating KLRG1 hi type 2 innate lymphoid cells and inhibits type 1 innate immunity against multiple myeloma. Immunology and Cell Biology, 99 (1) imcb.12390, 65-83. doi: 10.1111/imcb.12390

Tissue-resident lymphocytes: weaponized sentinels at barrier surfaces

Belz, Gabrielle T., Denman, Renae, Seillet, Cyril and Jacquelot, Nicolas (2020). Tissue-resident lymphocytes: weaponized sentinels at barrier surfaces. F1000Research, 9 691, 691. doi: 10.12688/f1000research.25234.1

A divergent transcriptional landscape underpins the development and functional branching of MAIT cells

Koay, Hui Fern, Su, Shian, Amann-Zalcenstein, Daniela, Daley, Stephen R, Comerford, Iain, Whyte, Carly E, Konstantinov, Igor E, d’Udekem, Yves, Baldwin, Tracey, Hickey, Peter F, Berzins, Stuart P, Mak, Jeffrey Y.W., Kallies, Axel, Chen, Zhenjun, Nussing, Simone, Kedzierska, Katherine, Mackay, Laura K, McColl, Shaun R, Deenick, Elissa K, Fairlie, David P, McCluskey, James, Goodnow, Christopher C, Ritchie, Matthew E, Belz, Gabrielle T, Naik, Shalin H, Pellicci, Daniel G and Godfrey, Dale I (2020). A divergent transcriptional landscape underpins the development and functional branching of MAIT cells. The Journal of Immunology, 204 (1_Supplement), 223.8-223.8. doi: 10.4049/jimmunol.204.supp.223.8

Neuropeptide coordination of mucosal immunity by regulating ILC3 activity

Belz, Gabrielle T (2020). Neuropeptide coordination of mucosal immunity by regulating ILC3 activity. The Journal of Immunology, 204 (1_Supplement), 148.4-148.4. doi: 10.4049/jimmunol.204.supp.148.4

Elucidating specificity opens a window to the complexity of both the innate and adaptive immune systems

Belz, Gabrielle T. (2020). Elucidating specificity opens a window to the complexity of both the innate and adaptive immune systems. Viral Immunology, 33 (3), 145-152. doi: 10.1089/vim.2019.0186

Author Correction: The neuropeptide VIP confers anticipatory mucosal immunity by regulating ILC3 activity

Seillet, Cyril, Luong, Kylie, Tellier, Julie, Jacquelot, Nicolas, Shen, Rui Dong, Hickey, Peter, Wimmer, Verena C, Whitehead, Lachlan, Rogers, Kelly, Smyth, Gordon K, Garnham, Alexandra L, Ritchie, Matthew E and Belz, Gabrielle T (2020). Author Correction: The neuropeptide VIP confers anticipatory mucosal immunity by regulating ILC3 activity. Nature immunology, 21 (3), 354-354. doi: 10.1038/s41590-020-0606-8

Membrane association of a model CD4 + T‐cell vaccine antigen confers enhanced yet incomplete protection against murid herpesvirus‐4 infection

Yunis, Joseph, Redwood, Alec J., Belz, Gabrielle T. and Stevenson, Philip G. (2020). Membrane association of a model CD4 + T‐cell vaccine antigen confers enhanced yet incomplete protection against murid herpesvirus‐4 infection. Immunology and Cell Biology, 98 (4) imcb.12319, 332-343. doi: 10.1111/imcb.12319

Innate lymphoid cells in colorectal cancers: a double-edged sword

Huang, Qiutong, Cao, Wang, Mielke, Lisa Anna, Seillet, Cyril, Belz, Gabrielle T. and Jacquelot, Nicolas (2020). Innate lymphoid cells in colorectal cancers: a double-edged sword. Frontiers in Immunology, 10 3080, 1-9. doi: 10.3389/fimmu.2019.03080

Self-reactive and polyreactive B cells are generated and selected in the germinal center during γ-herpesvirus infection

Sakakibara, Shuhei, Yasui, Teruhito, Jinzai, Hideyuki, O'donnell, Kristy, Tsai, Chao-Yuan, Minamitani, Takeharu, Takeda, Kazuya, Belz, Gabrielle T., Tarlinton, David M. and Kikutani, Hitoshi (2020). Self-reactive and polyreactive B cells are generated and selected in the germinal center during γ-herpesvirus infection. International immunology, 32 (1), 27-38. doi: 10.1093/intimm/dxz057

Therapeutic ISCOMATRIX™ adjuvant vaccine elicits effective anti-tumor immunity in the TRAMP-C1 mouse model of prostate cancer

Barr, Adele M., Silva, Anabel, Prato, Sandro, Belz, Gabrielle T., Maraskovsky, Eugene and Baz Morelli, Adriana (2020). Therapeutic ISCOMATRIX™ adjuvant vaccine elicits effective anti-tumor immunity in the TRAMP-C1 mouse model of prostate cancer. Cancer Immunology, Immunotherapy, 69 (10), 1959-1972. doi: 10.1007/s00262-020-02597-6

Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory

Soon, Megan S. F., Lee, Hyun Jae, Engel, Jessica A., Straube, Jasmin, Thomas, Bryce S., Pernold, Clara P. S., Clarke, Lachlan S., Laohamonthonkul, Pawat, Haldar, Rohit N., Williams, Cameron G., Lansink, Lianne I. M., Moreira, Marcela L., Bramhall, Michael, Koufariotis, Lambros T., Wood, Scott, Chen, Xi, James, Kylie R., Lönnberg, Tapio, Lane, Steven W., Belz, Gabrielle T., Engwerda, Christian R., Khoury, David S., Davenport, Miles P., Svensson, Valentine, Teichmann, Sarah A. and Haque, Ashraful (2020). Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory. Nature Immunology, 21 (12), 1597-1610. doi: 10.1038/s41590-020-0800-8

A divergent transcriptional landscape underpins the development and functional branching of MAIT cells

Koay, H-. F., Su, S., Amann-Zalcenstein, D., Daley, S. R., Comerford, I., Miosge, L., Whyte, C. E., Konstantinov, I. E., d'Udekem, Y., Baldwin, T., Hickey, P. F., Berzins, S. P., Mak, J. Y. W., Sontani, Y., Roots, C. M., Sidwell, T., Kallies, A., Chen, Z., Nüssing, S., Kedzierska, K., Mackay, L. K., McColl, S. R., Deenick, E. K., Fairlie, D. P., McCluskey, J., Goodnow, C. C., Ritchie, M. E., Belz, G. T., Naik, S. H. ... Godfrey, D. I. (2019). A divergent transcriptional landscape underpins the development and functional branching of MAIT cells. Science Immunology, 4 (41) eaay6039, eaay6039. doi: 10.1126/sciimmunol.aay6039

Transcription factor T-bet in B cells modulates germinal center polarization and antibody affinity maturation in response to malaria

Ly, Ann, Liao, Yang, Pietrzak, Halina, Ioannidis, Lisa J., Sidwell, Tom, Gloury, Renee, Doerflinger, Marcel, Triglia, Tony, Qin, Raymond Z., Groom, Joanna R., Belz, Gabrielle T., Good-Jacobson, Kim L., Shi, Wei, Kallies, Axel and Hansen, Diana S. (2019). Transcription factor T-bet in B cells modulates germinal center polarization and antibody affinity maturation in response to malaria. Cell Reports, 29 (8), 2257-2269.e6. doi: 10.1016/j.celrep.2019.10.087

RIPLET, and not TRIM25, is required for endogenous RIG-I-dependent antiviral responses

Hayman, Thomas J., Hsu, Alan C., Kolesnik, Tatiana B., Dagley, Laura F., Willemsen, Joschka, Tate, Michelle D., Baker, Paul J., Kershaw, Nadia J., Kedzierski, Lukasz, Webb, Andrew I., Wark, Peter A., Kedzierska, Katherine, Masters, Seth L., Belz, Gabrielle T., Binder, Marco, Hansbro, Philip M., Nicola, Nicos A. and Nicholson, Sandra E. (2019). RIPLET, and not TRIM25, is required for endogenous RIG-I-dependent antiviral responses. Immunology and Cell Biology, 97 (9), 840-852. doi: 10.1111/imcb.12284

CARD11 is dispensable for homeostatic responses and suppressive activity of peripherally induced FOXP3+ regulatory T cells

Policheni, Antonia, Horikawa, Keisuke, Milla, Liz, Kofler, Jennifer, Bouillet, Philippe, Belz, Gabrielle T., O'Reilly, Lorraine A., Goodnow, Christopher C., Strasser, Andreas and Gray, Daniel H. D. (2019). CARD11 is dispensable for homeostatic responses and suppressive activity of peripherally induced FOXP3+ regulatory T cells. Immunology and Cell Biology, 97 (8), 740-752. doi: 10.1111/imcb.12268

SIDT1 localizes to endolysosomes and mediates double-stranded RNA transport into the cytoplasm

Nguyen, Tan A., Smith, Blake R.C., Elgass, Kirstin D., Creed, Sarah J., Cheung, Shane, Tate, Michelle D., Belz, Gabrielle T., Wicks, Ian P., Masters, Seth L. and Pang, Ken C. (2019). SIDT1 localizes to endolysosomes and mediates double-stranded RNA transport into the cytoplasm. Journal of Immunology, 202 (12), 3483-3492. doi: 10.4049/jimmunol.1801369

Natural killer cells and anti-tumor immunity

Nicholson, Sandra E., Keating, Narelle and Belz, Gabrielle T. (2019). Natural killer cells and anti-tumor immunity. Molecular Immunology, 110, 40-47. doi: 10.1016/j.molimm.2017.12.002

Parallel worlds of the adaptive and innate immune cell networks

Huang, Qiutong and Belz, Gabrielle T. (2019). Parallel worlds of the adaptive and innate immune cell networks. Current Opinion in Immunology, 58, 53-59. doi: 10.1016/j.coi.2019.04.008

NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology

Schlenner, Susan, Pasciuto, Emanuela, Lagou, Vasiliki, Burton, Oliver, Prezzemolo, Teresa, Junius, Steffie, Roca, Carlos P, Seillet, Cyril, Louis, Cynthia, Dooley, James, Luong, Kylie, Van Nieuwenhove, Erika, Wicks, Ian P, Belz, Gabrielle, Humblet-Baron, Stéphanie, Wouters, Carine and Liston, Adrian (2019). NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology. Annals of the Rheumatic Diseases, 78 (3), 342-349. doi: 10.1136/annrheumdis-2018-213764

Pulmonary group 2 innate lymphoid cells: surprises and challenges

Starkey, Malcolm R., McKenzie, Andrew Nj., Belz, Gabrielle T. and Hansbro, Philip M. (2019). Pulmonary group 2 innate lymphoid cells: surprises and challenges. Mucosal Immunology, 12 (2), 299-311. doi: 10.1038/s41385-018-0130-4

Transcription factor PU.1 promotes conventional dendritic cell identity and function via induction of transcriptional regulator DC-SCRIPT

Chopin, Michaël, Lun, Aaron T., Zhan, Yifan, Schreuder, Jaring, Coughlan, Hannah, D'Amico, Angela, Mielke, Lisa A., Almeida, Francisca F., Kueh, Andrew J., Dickins, Ross A., Belz, Gabrielle T., Naik, Shalin H., Lew, Andrew M., Bouillet, Phillipe, Herold, Marco J., Smyth, Gordon K., Corcoran, Lynn M. and Nutt, Stephen L. (2019). Transcription factor PU.1 promotes conventional dendritic cell identity and function via induction of transcriptional regulator DC-SCRIPT. Immunity, 50 (1), 77-90.e5. doi: 10.1016/j.immuni.2018.11.010

Constitutive overexpression of TNF in BPSM1 mice causes iBALT and bone marrow nodular lymphocytic hyperplasia

Seillet, Cyril, Carr, Elysa, Lacey, Derek, Stutz, Michael D., Pellegrini, Marc, Whitehead, Lachlan, Rimes, Joel, Hawkins, Edwin D., Roediger, Ben, Belz, Gabrielle T. and Bouillet, Philippe (2019). Constitutive overexpression of TNF in BPSM1 mice causes iBALT and bone marrow nodular lymphocytic hyperplasia. Immunology and Cell Biology, 97 (1), 29-38. doi: 10.1111/imcb.12197

Context-dependent role for T-bet in T follicular helper differentiation and germinal center function following viral infection

Sheikh, Amania A., Cooper, Lucy, Feng, Meiqi, Souza-Fonseca-Guimaraes, Fernando, Lafouresse, Fanny, Duckworth, Brigette C., Huntington, Nicholas D., Moon, James J., Pellegrini, Marc, Nutt, Stephen L., Belz, Gabrielle T., Good-Jacobson, Kim L. and Groom, Joanna R. (2019). Context-dependent role for T-bet in T follicular helper differentiation and germinal center function following viral infection. Cell Reports, 28 (7), 1758-1772.e4. doi: 10.1016/j.celrep.2019.07.034

TCF-1 limits the formation of Tc17 cells via repression of the MAF–RORγt axis

Mielke, Lisa A., Liao, Yang, Clemens, Ella Bridie, Firth, Matthew A., Duckworth, Brigette, Huang, Qiutong, Almeida, Francisca F., Chopin, Michael, Koay, Hui-Fern, Bell, Carolyn A., Hediyeh-Zadeh, Soroor, Park, Simone L., Raghu, Dinesh, Choi, Jarny, Putoczki, Tracy L., Hodgkin, Philip D., Franks, Ashley E., Mackay, Laura K., Godfrey, Dale I., Davis, Melissa J., Xue, Hai-Hui, Bryant, Vanessa L., Kedzierska, Katherine, Shi, Wei and Belz, Gabrielle T. (2019). TCF-1 limits the formation of Tc17 cells via repression of the MAF–RORγt axis. Journal of Experimental Medicine, 216 (7), 1682-1699. doi: 10.1084/jem.20181778

The neuropeptide VIP confers anticipatory mucosal immunity by regulating ILC3 activity

Seillet, Cyril, Luong, Kylie, Tellier, Julie, Jacquelot, Nicolas, Shen, Rui Dong, Hickey, Peter, Wimmer, Verena C., Whitehead, Lachlan, Rogers, Kelly, Smyth, Gordon K., Garnham, Alexandra L., Ritchie, Matthew E. and Belz, Gabrielle T. (2019). The neuropeptide VIP confers anticipatory mucosal immunity by regulating ILC3 activity. Nature Immunology, 21 (2), 168-177. doi: 10.1038/s41590-019-0567-y

Assessing the role of the T-box transcription factor Eomes in B cell differentiation during either Th1 or Th2 cell-biased responses

Cooper, Lucy, Hailes, Lauren, Sheikh, Amania, Zaph, Colby, Belz, Gabrielle T., Groom, Joanna R. and Good-Jacobson, Kim L. (2018). Assessing the role of the T-box transcription factor Eomes in B cell differentiation during either Th1 or Th2 cell-biased responses. PLoS One, 13 (12) e0208343, e0208343. doi: 10.1371/journal.pone.0208343

Deconstructing deployment of the innate immune lymphocyte army for barrier homeostasis and protection

Almeida, Francisca F., Jacquelot, Nicolas and Belz, Gabrielle T. (2018). Deconstructing deployment of the innate immune lymphocyte army for barrier homeostasis and protection. Immunological Reviews, 286 (1), 6-22. doi: 10.1111/imr.12709

A point mutation in the Ncr1 signal peptide impairs the development of innate lymphoid cell subsets

Almeida, Francisca F., Tognarelli, Sara, Marçais, Antoine, Kueh, Andrew J., Friede, Miriam E., Liao, Yang, Willis, Simon N., Luong, Kylie, Faure, Fabrice, Mercier, Francois E., Galluso, Justine, Firth, Matthew, Narni-Mancinelli, Emilie, Rais, Bushra, Scadden, David T., Spallotta, Francesco, Weil, Sandra, Giannattasio, Ariane, Kalensee, Franziska, Zöller, Tobias, Huntington, Nicholas D., Schleicher, Ulrike, Chiocchetti, Andreas G., Ugolini, Sophie, Herold, Marco J., Shi, Wei, Koch, Joachim, Steinle, Alexander, Vivier, Eric ... Ullrich, Evelyn (2018). A point mutation in the Ncr1 signal peptide impairs the development of innate lymphoid cell subsets. OncoImmunology, 7 (10) e1475875, e1475875. doi: 10.1080/2162402X.2018.1475875

Characterization of Blimp-1 function in effector regulatory T cells

Cretney, Erika, Leung, Patrick SK., Trezise, Stephanie, Newman, Dane M., Rankin, Lucille C., Teh, Charis E., Putoczki, Tracy L., Gray, Daniel HD., Belz, Gabrielle T., Mielke, Lisa A., Dias, Sheila and Nutt, Stephen L. (2018). Characterization of Blimp-1 function in effector regulatory T cells. Journal of Autoimmunity, 91, 73-82. doi: 10.1016/j.jaut.2018.04.003

Starvation suppresses T cell appetite

Belz, Gabrielle (2018). Starvation suppresses T cell appetite. Nature Reviews Immunology, 18 (7), 421-421. doi: 10.1038/s41577-018-0021-7

Bach2: an instrument of heterogeneity for long-term protection

Huang, Qiutong and Belz, Gabrielle T. (2018). Bach2: an instrument of heterogeneity for long-term protection. Immunity, 48 (4), 618-620. doi: 10.1016/j.immuni.2018.03.033

The immunological functions of the Appendix: an example of redundancy?

Girard-Madoux, Mathilde J.H., Gomez de Agüero, Mercedes, Ganal-Vonarburg, Stephanie C., Mooser, Catherine, Belz, Gabrielle T., Macpherson, Andrew J. and Vivier, Eric (2018). The immunological functions of the Appendix: an example of redundancy?. Seminars in Immunology, 36 (C), 31-44. doi: 10.1016/j.smim.2018.02.005

Flt-3L expansion of recipient CD8α+ dendritic cells deletes alloreactive donor T cells and represents an alternative to post-transplant cyclophosphamide for the prevention of GVHD

Markey, Kate A., Kuns, Rachel D., Browne, Daniel J., Gartlan, Kate H., Robb, Renee J., Martins, J. Paulo, Henden, Andrea S., Minnie, Simone A., Cheong, Melody, Koyama, Motoko, Smyth, Mark J., Steptoe, Raymond J., Belz, Gabrielle, Brocker, Thomas, Degli-Esposti, Mariapia A., Lane, Steven W. and Hill, Geoffrey R. (2018). Flt-3L expansion of recipient CD8α+ dendritic cells deletes alloreactive donor T cells and represents an alternative to post-transplant cyclophosphamide for the prevention of GVHD. Clinical Cancer Research, 24 (7), 1604-1616. doi: 10.1158/1078-0432.CCR-17-2148

Characterisation of innate lymphoid cell populations at different sites in mice with defective T cell immunity [version 3; referees: 2 approved]

Dutton, Emma E., Camelo, Ana, Sleeman, Matthew, Herbst, Ronald, Carlesso, Gianluca, Belz, Gabrielle T. and Withers, David R. (2018). Characterisation of innate lymphoid cell populations at different sites in mice with defective T cell immunity [version 3; referees: 2 approved]. Wellcome Open Research, 2 117, 117. doi: 10.12688/wellcomeopenres.13199.3

Targeting chemokines and chemokine receptors in melanoma and other cancers

Jacquelot, Nicolas, Duong, Connie P. M., Belz, Gabrielle T. and Zitvogel, Laurence (2018). Targeting chemokines and chemokine receptors in melanoma and other cancers. Frontiers in immunology, 9 2480. doi: 10.3389/fimmu.2018.02480

Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation

Infantino, Simona, Light, Amanda, O'donnell, Kristy, Bryant, Vanessa, Avery, Danielle T., Elliott, Michael, Tangye, Stuart G., Belz, Gabrielle, Mackay, Fabienne, Richard, Stephane and Tarlinton, David (2017). Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation. Nature Communications, 8 (1) 891, 891. doi: 10.1038/s41467-017-01009-1

Shaping innate lymphoid cell diversity

Huang, Qiutong, Seillet, Cyril and Belz, Gabrielle T. (2017). Shaping innate lymphoid cell diversity. Frontiers in Immunology, 8 (NOV) 1569, 1569. doi: 10.3389/fimmu.2017.01569

SIDT2 transports extracellular dsRNA into the cytoplasm for innate immune recognition

Nguyen, Tan A., Smith, Blake R.C., Tate, Michelle D., Belz, Gabrielle T., Barrios, Marilou H., Elgass, Kirstin D., Weisman, Alexandra S., Baker, Paul J., Preston, Simon P., Whitehead, Lachlan, Garnham, Alexandra, Lundie, Rachel J., Smyth, Gordon K., Pellegrini, Marc, O'Keeffe, Meredith, Wicks, Ian P., Masters, Seth L., Hunter, Craig P. and Pang, Ken C. (2017). SIDT2 transports extracellular dsRNA into the cytoplasm for innate immune recognition. Immunity, 47 (3), 498-509.e6. doi: 10.1016/j.immuni.2017.08.007

Natural-killer-like B cells display the phenotypic and functional characteristics of conventional B cells

Kerdiles, Yann M., Almeida, Francisca F., Thompson, Thornton, Chopin, Michael, Vienne, Margaux, Bruhns, Pierre, Huntington, Nicholas D., Raulet, David H., Nutt, Stephen L., Belz, Gabrielle T. and Vivier, Eric (2017). Natural-killer-like B cells display the phenotypic and functional characteristics of conventional B cells. Immunity, 47 (2), 199-200. doi: 10.1016/j.immuni.2017.07.026

Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells

Gao, Yulong, Souza-Fonseca-Guimaraes, Fernando, Bald, Tobias, Ng, Susanna S., Young, Arabella, Ngiow, Shin Foong, Rautela, Jai, Straube, Jasmin, Waddell, Nic, Blake, Stephen J., Yan, Juming, Bartholin, Laurent, Lee, Jason S., Vivier, Eric, Takeda, Kazuyoshi, Messaoudene, Meriem, Zitvogel-, Laurence, Teng, Michele W. L., Belz, Gabrielle T., Engwerda, Christian R., Huntington, Nicholas D., Nakamura, Kyohei, Hoelzel, Michael and Smyth, Mark J. (2017). Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells. Nature Immunology, 18 (9), 1004-1015. doi: 10.1038/ni.3800

Local modulation of antigen-presenting cell development after resolution of pneumonia induces long-term susceptibility to secondary infections

Roquilly, Antoine, McWilliam, Hamish E.G., Jacqueline, Cedric, Tian, Zehua, Cinotti, Raphael, Rimbert, Marie, Wakim, Linda, Caminschi, Irina, Lahoud, Mireille H., Belz, Gabrielle T., Kallies, Axel, Mintern, Justine D., Asehnoune, Karim and Villadangos, Jose A. (2017). Local modulation of antigen-presenting cell development after resolution of pneumonia induces long-term susceptibility to secondary infections. Immunity, 47 (1), 135-147.e5. doi: 10.1016/j.immuni.2017.06.021

Androgen signaling negatively controls group 2 innate lymphoid cells

Laffont, Sophie, Blanquart, Eve, Savignac, Magali, Cénac, Claire, Laverny, Gilles, Metzger, Daniel, Girard, Jean-Philippe, Belz, Gabrielle T., Pelletier, Lucette, Seillet, Cyril and Guéry, Jean-Charles (2017). Androgen signaling negatively controls group 2 innate lymphoid cells. Journal of Experimental Medicine, 214 (6), 1581-1592. doi: 10.1084/jem.20161807

Monocyte-derived dendritic cells: A transendothelial trip launches the quest to understand heterogeneity in the APC family

Belz, Gabrielle T. (2017). Monocyte-derived dendritic cells: A transendothelial trip launches the quest to understand heterogeneity in the APC family. Journal of Immunology, 198 (11), 4189-4190. doi: 10.4049/jimmunol.1700527

Unusual suspects: Dancing with stromal cells

Belz, Gabrielle T. and Almeida, Francisca F. (2017). Unusual suspects: Dancing with stromal cells. Nature Immunology, 18 (6), 601-602. doi: 10.1038/ni.3741

c-Myb regulates the T-bet-dependent differentiation program in B cells to coordinate antibody responses

Piovesan, Dana, Tempany, Jessica, Di Pietro, Andrea, Baas, Inge, Yiannis, Callisthenis, O'Donnell, Kristy, Chen, Yunshun, Peperzak, Victor, Belz, Gabrielle T., Mackay, Charles R., Smyth, Gordon K., Groom, Joanna R., Tarlinton, David M. and Good-Jacobson, Kim L. (2017). c-Myb regulates the T-bet-dependent differentiation program in B cells to coordinate antibody responses. Cell Reports, 19 (3), 461-470. doi: 10.1016/j.celrep.2017.03.060

Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression

Poh, Ashleigh R., Love, Christopher G., Masson, Frederick, Preaudet, Adele, Tsui, Cary, Whitehead, Lachlan, Monard, Simon, Khakham, Yelena, Burstroem, Lotta, Lessene, Guillaume, Sieber, Oliver, Lowell, Clifford, Putoczki, Tracy L., O'Donoghue, Robert J. J. and Ernst, Matthias (2017). Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression. Cancer Cell, 31 (4), 563-+. doi: 10.1016/j.ccell.2017.03.006

Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells

Zhang, Ping, Lee, Jason S., Gartlan, Kate H., Schuster, Iona S., Comerford, Iain, Varelias, Antiopi, Ullah, Md Ashik, Vuckovic, Slavica, Koyama, Motoko, Kuns, Rachel D., Locke, Kelly R., Beckett, Kirrilee J., Olver, Stuart D., Samson, Luke D., Montes de Oca, Marcela, de Labastida Rivera, Fabian, Clouston, Andrew D., Belz, Gabrielle T., Blazar, Bruce R., MacDonald, Kelli P., McColl, Shaun R., Thomas, Ranjeny, Engwerda, Christian R., Degli-Esposti, Mariapia A., Kallies, Axel, Tey, Siok-Keen and Hill, Geoffrey R. (2017). Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells. Science Immunology, 2 (10) eaah7152. doi: 10.1126/sciimmunol.aah7152

Suppressor of cytokine signaling (SOCS)5 ameliorates influenza infection via inhibition of EGFR signaling

Kedzierski, Lukasz, Tate, Michelle D., Hsu, Alan C., Kolesnik, Tatiana B., Linossi, Edmond M., Dagley, Laura, Dong, Zhaoguang, Freeman, Sarah, Infusini, Giuseppe, Starkey, Malcolm R., Bird, Nicola L., Chatfield, Simon M., Babon, Jeffrey J., Huntington, Nicholas, Belz, Gabrielle, Webb, Andrew, Wark, Peter Ab., Nicola, Nicos A., Xu, Jianqing, Kedzierska, Katherine, Hansbro, Philip M. and Nicholson, Sandra E. (2017). Suppressor of cytokine signaling (SOCS)5 ameliorates influenza infection via inhibition of EGFR signaling. eLife, 6 e20444. doi: 10.7554/eLife.20444

Cell cycle progression dictates the requirement for BCL2 in natural killer cell survival

Viant, Charlotte, Guia, Sophie, Hennessy, Robert J., Rautela, Jai, Pham, Kim, Bernat, Claire, Goh, Wilford, Jiao, Yuhao, Delconte, Rebecca, Roger, Michael, Simon, Vanina, Souza-Fonseca-Guimaraes, Fernando, Grabow, Stephanie, Belz, Gabrielle T., Kile, Benjamin T., Strasser, Andreas, Gray, Daniel, Hodgkin, Phillip D., Beutler, Bruce, Vivier, Eric, Ugolini, Sophie and Huntington, Nicholas D. (2017). Cell cycle progression dictates the requirement for BCL2 in natural killer cell survival. Journal of Experimental Medicine, 214 (2), 491-510. doi: 10.1084/jem.20160869

Effector regulatory T cell differentiation and immune homeostasis depend on the transcription factor Myb

Dias, Sheila, D'Amico, Angela, Cretney, Erika, Liao, Yang, Tellier, Julie, Bruggeman, Christine, Almeida, Francisca F., Leahy, Jamie, Belz, Gabrielle T., Smyth, Gordon K., Shi, Wei and Nutt, Stephen L. (2017). Effector regulatory T cell differentiation and immune homeostasis depend on the transcription factor Myb. Immunity, 46 (1), 78-91. doi: 10.1016/j.immuni.2016.12.017

Batf3 selectively determines acquisition of CD8+ dendritic cell phenotype and function

Chandra, Janin, Kuo, Paula T. Y., Hahn, Anne M., Belz, Gabrielle T. and Frazer, Ian H. (2016). Batf3 selectively determines acquisition of CD8+ dendritic cell phenotype and function. Immunology and Cell Biology, 95 (2), 215-223. doi: 10.1038/icb.2016.83

A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage

Koay, Hui-Fern, Gherardin, Nicholas A., Enders, Anselm, Loh, Liyen, Mackay, Laura K., Almeida, Catarina F., Russ, Brendan E., Nold-Petry, Claudia A., Nold, Marcel F., Bedoui, Sammy, Chen, Zhenjun, Corbett, Alexandra J., Eckle, Sidonia B. G., Meehan, Bronwyn, D'Udekem, Yves, Konstantinov, Igor E., Lappas, Martha, Liu, Ligong, Goodnow, Chris C., Fairlie, David P., Rossjohn, Jamie, Chong, Mark M., Kedzierska, Katherine, Berzins, Stuart P., Belz, Gabrielle T., McCluskey, James, Uldrich, Adam P., Godfrey, Dale I. and Pellicci, Daniel G. (2016). A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage. Nature Immunology, 17 (11), 1300-1311. doi: 10.1038/ni.3565

Immunology & Cell Biology Publication of the Year Awards 2015

Belz, Gabrielle (2016). Immunology & Cell Biology Publication of the Year Awards 2015. Immunology and Cell Biology, 94 (10), 901-902. doi: 10.1038/icb.2016.86

Type 1 innate lymphoid cell biology: Lessons learnt from natural killer cells

Jiao, Yuhao, Huntington, Nicholas D., Belz, Gabrielle T. and Seillet, Cyril (2016). Type 1 innate lymphoid cell biology: Lessons learnt from natural killer cells. Frontiers in Immunology, 7 (OCT) 426. doi: 10.3389/fimmu.2016.00426

Deciphering the innate lymphoid cell transcriptional program

Seillet, Cyril, Mielke, Lisa A., Amann-Zalcenstein, Daniela B., Su, Shian, Gao, Jerry, Almeida, Francisca F., Shi, Wei, Ritchie, Matthew E., Naik, Shalin H., Huntington, Nicholas D., Carotta, Sebastian and Belz, Gabrielle T. (2016). Deciphering the innate lymphoid cell transcriptional program. Cell Reports, 17 (2), 436-447. doi: 10.1016/j.celrep.2016.09.025

CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles

Leong, Yew Ann, Chen, Yaping, Ong, Hong Sheng, Wu, Di, Man, Kevin, Deleage, Claire, Minnich, Martina, Meckiff, Benjamin J., Wei, Yunbo, Hou, Zhaohua, Zotos, Dimitra, Fenix, Kevin A., Atnerkar, Anurag, Preston, Simon, Chipman, Jeffrey G., Beilman, Greg J., Allison, Cody C., Sun, Lei, Wang, Peng, Xu, Jiawei, Toe, Jesse G., Lu, Hao K., Tao, Yong, Palendira, Umaimainthan, Dent, Alexander L., Landay, Alan L., Pellegrini, Marc, Comerford, Iain, McColl, Shaun R. ... Yu, Di (2016). CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles. Nature Immunology, 17 (10), 1187-+. doi: 10.1038/ni.3543

Single-cell RNA-seq identifies a PD-1hi ILC progenitor and defines its development pathway

Yu, Yong, Tsang, Jason C. H., Wang, Cui, Clare, Simon, Wang, Juexuan, Chen, Xi, Brandt, Cordelia, Kane, Leanne, Campos, Lia S., Lu, Liming, Belz, Gabrielle T., McKenzie, Andrew N. J., Teichmann, Sarah A., Dougan, Gordon and Liu, Pentao (2016). Single-cell RNA-seq identifies a PD-1hi ILC progenitor and defines its development pathway. Nature, 539 (7627), 102-106. doi: 10.1038/nature20105

Acetylation of the Cd8 Locus by KAT6A Determines Memory T Cell Diversity

Newman, Dane M., Sakaguchi, Shinya, Lun, Aaron, Preston, Simon, Pellegrini, Marc, Khamina, Kseniya, Bergthaler, Andreas, Nutt, Stephen L., Smyth, Gordon K., Voss, Anne K., Thomas, Tim, Ellmeier, Wilfried, Belz, Gabrielle T. and Allan, Rhys S. (2016). Acetylation of the Cd8 Locus by KAT6A Determines Memory T Cell Diversity. Cell Reports, 16 (12), 3311-3321. doi: 10.1016/j.celrep.2016.08.056

Innate lymphoid cells: models of plasticity for immune homeostasis and rapid responsiveness in protection

Almeida, F. F. and Belz, G. T. (2016). Innate lymphoid cells: models of plasticity for immune homeostasis and rapid responsiveness in protection. Mucosal Immunology, 9 (5), 1103-1112. doi: 10.1038/mi.2016.64

Id2 and E proteins orchestrate the initiation and maintenance of MLL-rearranged acute myeloid leukemia

Ghisi, Margherita, Kats, Lev, Masson, Frederick, Li, Jason, Kratina, Tobias, Vidacs, Eva, Gilan, Omer, Doyle, Maria A., Newbold, Andrea, Bolden, Jessica E., Fairfax, Kirsten A., de Graaf, Carolyn A., Firth, Matthew, Zuber, Johannes, Dickins, Ross A., Corcoran, Lynn M., Dawson, Mark A., Belz, Gabrielle T. and Johnstone, Ricky W. (2016). Id2 and E proteins orchestrate the initiation and maintenance of MLL-rearranged acute myeloid leukemia. Cancer Cell, 30 (1), 59-74. doi: 10.1016/j.ccell.2016.05.019

CIS is a potent checkpoint in NK cell-mediated tumor immunity

Delconte, Rebecca B., Kolesnik, Tatiana B., Dagley, Laura F., Rautela, Jai, Shi, Wei, Putz, Eva M., Stannard, Kimberley, Zhang, Jian-Guo, Teh, Charis, Firth, Matt, Ushiki, Takashi, Andoniou, Christopher E., Degli-Esposti, Mariapia A., Sharp, Phillip P., Sanvitale, Caroline E., Infusini, Giuseppe, Liau, Nicholas P. D., Linossi, Edmond M., Burns, Christopher J., Carotta, Sebastian, Gray, Daniel H. D., Seillet, Cyril, Hutchinson, Dana S., Belz, Gabrielle T., Webb, Andrew I., Alexander, Warren S., Li, Shawn S., Bullock, Alex N., Babon, Jeffery J. ... Huntington, Nicholas D. (2016). CIS is a potent checkpoint in NK cell-mediated tumor immunity. Nature Immunology, 17 (7), 816-824. doi: 10.1038/ni.3470

Granzyme M has a critical role in providing innate immune protection in ulcerative colitis

Souza-Fonseca-Guimaraes, F., Krasnova, Y., Putoczki, T., Miles, K., MacDonald, K. P., Town, L., Shi, W., Gobe, G. C., McDade, L., Mielke, L. A., Tye, H., Masters, S. L., Belz, G. T., Huntington, N. D., Radford-Smith, G. and Smyth, M. J. (2016). Granzyme M has a critical role in providing innate immune protection in ulcerative colitis. Cell Death and Disease, 7 (7) e2302, e2302-e2302. doi: 10.1038/cddis.2016.215

The evolution of innate lymphoid cells

Vivier, Eric, Van De Pavert, Serge A., Cooper, Max D. and Belz, Gabrielle T. (2016). The evolution of innate lymphoid cells. Nature Immunology, 17 (7), 790-794. doi: 10.1038/ni.3459

Type I interferons direct gammaherpesvirus host colonization

Tan, Cindy S. E., Lawler, Clara, May, Janet S., Belz, Gabrielle T. and Stevenson, Philip G. (2016). Type I interferons direct gammaherpesvirus host colonization. PLoS Pathogens, 12 (5) e1005654, e1005654. doi: 10.1371/journal.ppat.1005654

ILC2s masquerade as ILC1s to drive chronic disease

Belz, Gabrielle T. (2016). ILC2s masquerade as ILC1s to drive chronic disease. Nature Immunology, 17 (6), 611-612. doi: 10.1038/ni.3467

Transforming growth factor-β and Notch ligands act as opposing environmental cues in regulating the plasticity of type 3 innate lymphoid cells

Viant, Charlotte, Rankin, Lucille C., Girard-Madoux, Mathilde J. H., Seillet, Cyril, Shi, Wei, Smyth, Mark J., Bartholin, Laurent, Walzer, Thierry, Huntington, Nicholas D., Vivier, Eric and Belz, Gabrielle T. (2016). Transforming growth factor-β and Notch ligands act as opposing environmental cues in regulating the plasticity of type 3 innate lymphoid cells. Science Signaling, 9 (426) ra46, ra46-ra46. doi: 10.1126/scisignal.aaf2176

Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development

Gloury, Renee, Zotos, Dimitra, Zuidscherwoude, Malou, Masson, Frederick, Liao, Yang, Hasbold, Jhaguaral, Corcoran, Lynn M., Hodgkin, Phil D., Belz, Gabrielle T., Shi, Wei, Nutt, Stephen L., Tarlinton, David M. and Kallies, Axel (2016). Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development. Journal of Experimental Medicine, 213 (6), 1095-1111. doi: 10.1084/jem.20152003

RUNX2 mediates plasmacytoid dendritic cell egress from the bone marrow and controls viral immunity

Chopin, Michaël, Preston, Simon P., Lun, Aaron T.L., Tellier, Julie, Smyth, Gordon K., Pellegrini, Marc, Belz, Gabrielle T., Corcoran, Lynn M., Visvader, Jane E., Wu, Li and Nutt, Stephen L. (2016). RUNX2 mediates plasmacytoid dendritic cell egress from the bone marrow and controls viral immunity. Cell Reports, 15 (4), 866-878. doi: 10.1016/j.celrep.2016.03.066

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

Mackay, Laura K., Minnich, Martina, Kragten, Natasja A. M., Liao, Yang, Nota, Benjamin, Seillet, Cyril, Zaid, Ali, Man, Kevin, Preston, Simon, Freestone, David, Braun, Asolina, Wynne-Jones, Erica, Behr, Felix M., Stark, Regina, Pellicci, Daniel G., Godfrey, Dale I., Belz, Gabrielle T., Pellegrini, Marc, Gebhardt, Thomas, Busslinger, Meinrad, Shi, Wei, Carbone, Francis R., Van Lier, René A.W., Kallies, Axel and Van Gisbergen, Klaas P. J. M. (2016). Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes. Science, 352 (6284), 459-463. doi: 10.1126/science.aad2035

A molecular threshold for effector CD8+ T cell differentiation controlled by transcription factors Blimp-1 and T-bet

Xin, Annie, Masson, Frederick, Liao, Yang, Preston, Simon, Guan, Tianxia, Gloury, Renee, Olshansky, Moshe, Lin, Jian-Xin, Li, Peng, Speed, Terence P., Smyth, Gordon K., Ernst, Matthias, Leonard, Warren J., Pellegrini, Marc, Kaech, Susan M., Nutt, Stephen L., Shi, Wei, Belz, Gabrielle T. and Kallies, Axel (2016). A molecular threshold for effector CD8+ T cell differentiation controlled by transcription factors Blimp-1 and T-bet. Nature Immunology, 17 (4), 422-432. doi: 10.1038/ni.3410

Lethal giant larvae-1 deficiency enhances the CD8+ effector T-cell response to antigen challenge in vivo

Ramsbottom, Kelly M., Sacirbegovic, Faruk, Hawkins, Edwin D., Kallies, Axel, Belz, Gabrielle T., Van Ham, Vanessa, Haynes, Nicole M., Durrant, Michael J., Humbert, Patrick O., Russell, Sarah M. and Oliaro, Jane (2016). Lethal giant larvae-1 deficiency enhances the CD8+ effector T-cell response to antigen challenge in vivo. Immunology and Cell Biology, 94 (3), 306-311. doi: 10.1038/icb.2015.82

Complementarity and redundancy of IL-22-producing innate lymphoid cells

Rankin, Lucille C., Girard-Madoux, Mathilde J. H., Seillet, Cyril, Mielke, Lisa A., Kerdiles, Yann, Fenis, Aurore, Wieduwild, Elisabeth, Putoczki, Tracy, Mondot, Stanislas, Lantz, Olivier, Demon, Dieter, Papenfuss, Anthony T., Smyth, Gordon K., Lamkanfi, Mohamed, Carotta, Sebastian, Renauld, Jean-Christophe, Shi, Wei, Carpentier, Sabrina, Soos, Tim, Arendt, Christopher, Ugolini, Sophie, Huntington, Nicholas D, Belz, Gabrielle T. and Vivier, Eric (2016). Complementarity and redundancy of IL-22-producing innate lymphoid cells. Nature Immunology, 17 (2), 179-186. doi: 10.1038/ni.3332

Development, homeostasis, and heterogeneity of NK cells and ILC1

Seillet, Cyril, Belz, Gabrielle T. and Huntington, Nicholas D. (2016). Development, homeostasis, and heterogeneity of NK cells and ILC1. Current Topics in Microbiology and Immunology, 395, 37-61. doi: 10.1007/82_2015_474

Innate lymphoid cells: Parallel checkpoints and coordinate interactions with T cells

Huntington, Nicholas D, Carpentier, Sabrina, Vivier, Eric and Belz, Gabrielle T (2016). Innate lymphoid cells: Parallel checkpoints and coordinate interactions with T cells. Current Opinion in Immunology, 38, 86-93. doi: 10.1016/j.coi.2015.11.008

The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15

Delconte, Rebecca B., Shi, Wei, Sathe, Priyanka, Ushiki, Takashi, Seillet, Cyril, Minnich, Martina, Kolesnik, Tatiana B., Rankin, Lucille C., Mielke, Lisa A., Zhang, Jian-Guo, Busslinger, Meinrad, Smyth, Mark J., Hutchinson, Dana S., Nutt, Stephen L., Nicholson, Sandra E., Alexander, Warren S., Corcoran, Lynn M., Vivier, Eric, Belz, Gabrielle, Carotta, Sebastian and Huntington, Nicholas D. (2016). The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15. Immunity, 44 (1), 103-115. doi: 10.1016/j.immuni.2015.12.007

Differentiation and diversity of subsets in group 1 innate lymphoid cells

Seillet, Cyril and Belz, Gabrielle T. (2016). Differentiation and diversity of subsets in group 1 innate lymphoid cells. International Immunology, 28 (1), 3-11. doi: 10.1093/intimm/dxv051

CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells

Kara, Ervin E., McKenzie, Duncan R., Bastow, Cameron R., Gregor, Carly E., Fenix, Kevin A., Ogunniyi, Abiodim D., Paton, James C., Mack, Matthias, Pombal, Diana R., Seillet, Cyrill, Dubois, Benedocte, Liston, Adrian, Macdonald, Kelli P. A., Belz, Gabrielle T., Smyth, Mark J., Hill, Geoffrey R., Comerford, Iain and McColl, Shaun R. (2015). CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells. Nature Communications, 6 (1) 8644, 8644. doi: 10.1038/ncomms9644

A role for the mitochondrial protein Mrpl44 in maintaining OXPHOS capacity

Yeo, Janet H.C., Skinner, Jarrod P.J., Bird, Matthew J., Formosa, Luke E., Zhang, Jian- Guo, Kluck, Ruth M., Belz, Gabrielle T. and Chong, Mark M.W. (2015). A role for the mitochondrial protein Mrpl44 in maintaining OXPHOS capacity. PLoS One, 10 (7) e0134326. doi: 10.1371/journal.pone.0134326

Donor colonic CD103(+) dendritic cells determine the severity of acute graft-versus-host disease

Koyama, Motoko, Cheong, Melody, Markey, Kate A., Gartlan, Kate H., Kuns, Rachel D., Locke, Kelly R., Lineburg, Katie E., Teal, Bianca E., Leveque-El Mouttie, Lucie, Bunting, Mark D., Vuckovic, Slavica, Zhang, Ping, Teng, Michele W. L., Varelias, Antiopi, Tey, Siok-Keen, Wockner, Leesa F., Engwerda, Christian R., Smyth, Mark J., Belz, Gabrielle T., McColl, Shaun R., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2015). Donor colonic CD103(+) dendritic cells determine the severity of acute graft-versus-host disease. Journal of Experimental Medicine, 212 (8), 1303-1321. doi: 10.1084/jem.20150329

Confocal laser endomicroscopy to monitor the colonic mucosa of mice

Mielke, Lisa, Preaudet, Adele, Belz, Gabrielle and Putoczki, Tracy (2015). Confocal laser endomicroscopy to monitor the colonic mucosa of mice. Journal of Immunological Methods, 421, 81-88. doi: 10.1016/j.jim.2015.04.012

CD3 bright signals on γδ T cells identify IL-17A-producing Vγ6Vδ1+T cells

Paget, C., Chow, M. T., Gherardin, N. A., Beavis, P. A., Uldrich, A. P., Duret, H., Hassane, M., Souza-Fonseca-Guimaraes, F., Mogilenko, D. A., Staumont-Salle, D., Escalante, N. K., Hill, G. R., Neeson, P., Ritchie, D. S., Dombrowicz, D., Mallevaey, T., Trottein, F., Belz, G. T., Godfrey, D. I. and Smyth, M. J. (2015). CD3 bright signals on γδ T cells identify IL-17A-producing Vγ6Vδ1+T cells. Immunology and Cell Biology, 93 (2), 198-212. doi: 10.1038/icb.2014.94

Bcl11b is essential for group 2 innate lymphoid cell development

Walker, Jennifer A., Oliphant, Christopher J., Englezakis, Alexandros, Yu, Yong, Clare, Simon, Rodewald, Hans-Reimer, Belz, Gabrielle, Liu, Pentao, Fallon, Padraic G. and McKenzie, Andrew N.J. (2015). Bcl11b is essential for group 2 innate lymphoid cell development. Journal of Experimental Medicine, 212 (6), 875-882. doi: 10.1084/jem.20142224

Immunology and Cell Biology Publication of the Year Awards 2014

Belz, Gabrielle (2015). Immunology and Cell Biology Publication of the Year Awards 2014. Immunology and Cell Biology, 93 (10), 837-838. doi: 10.1038/icb.2015.86

SOCS4 is dispensable for an efficient recall response to influenza despite being required for primary immunity

Kedzierski, Lukasz, Clemens, E Bridie, Bird, Nicola L., Kile, Benjamin T., Belz, Gabrielle T., Nicola, Nicos A., Kedzierska, Katherine and Nicholson, Sandra E. (2015). SOCS4 is dispensable for an efficient recall response to influenza despite being required for primary immunity. Immunology and Cell Biology, 93 (10), 909-913. doi: 10.1038/icb.2015.55

T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate

Mackay, Laura K., Wynne-Jones, Erica, Freestone, David, Pellicci, Daniel G., Mielke, Lisa A., Newman, Dane M., Braun, Asolina, Masson, Frederick, Kallies, Axel, Belz, Gabrielle T. and Carbone, Francis R. (2015). T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate. Immunity, 43 (6), 1101-1111. doi: 10.1016/j.immuni.2015.11.008

c-Myb is required for plasma cell migration to bone marrow after immunization or infection

Good-Jacobson, Kim L., O'Donnell, Kristy, Belz, Gabrielle T., Nutt, Stephen L. and Tarlinton, David M. (2015). c-Myb is required for plasma cell migration to bone marrow after immunization or infection. Journal of Experimental Medicine, 212 (7), 1001-1009. doi: 10.1084/jem.20150191

Antigen affinity, costimulation, and cytokine inputs sum linearly to amplify T cell expansion

Marchingo, Julia M., Kan, Andrey, Sutherland, Robyn M., Duffy, Ken R., Wellard, Cameron J., Belz, Gabrielle T., Lew, Andrew M., Dowling, Mark R., Heinzel, Susanne and Hodgkin, Philip D. (2014). Antigen affinity, costimulation, and cytokine inputs sum linearly to amplify T cell expansion. Science, 346 (6213), 1123-1127. doi: 10.1126/science.1260044

Peripheral natural killer cell maturation depends on the transcription factor Aiolos

Holmes, Melissa L., Huntington, Nicholas D., Thong, Rebecca P. L., Brady, Jason, Hayakawa, Yoshihiro, Andoniou, Christopher E., Fleming, Peter, Shi, Wei, Smyth, Gordon K., Degli-Esposti, Mariapia A., Belz, Gabrielle T., Kallies, Axel, Carotta, Sebastian, Smyth, Mark J. and Nutt, Stephen L. (2014). Peripheral natural killer cell maturation depends on the transcription factor Aiolos. EMBO Journal, 33 (22), 2721-2734. doi: 10.15252/embj.201487900

Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells

Sathe, Priyanka, Delconte, Rebecca B., Souza-Fonseca-Guimaraes, Fernando, Seillet, Cyril, Chopin, Michael, Vandenberg, Cassandra J., Rankin, Lucille C., Mielke, Lisa A., Vikstrom, Ingela, Kolesnik, Tatiana B., Nicholson, Sandra E., Vivier, Eric, Smyth, Mark J., Nutt, Stephen L., Glaser, Stefan P., Strasser, Andreas, Belz, Gabrielle T., Carotta, Sebastian and Huntington, Nicholas D. (2014). Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells. Nature Communications, 5 (1) 4539, 1-10. doi: 10.1038/ncomms5539

Id2 represses E2A-mediated activation of IL-10 expression in T cells

Masson, Frederick, Ghisi, Margherita, Groom, Joanna R., Kallies, Axel, Seillet, Cyril, Johnstone, Ricky W., Nutt, Stephen L. and Belz, Gabrielle T. (2014). Id2 represses E2A-mediated activation of IL-10 expression in T cells. Blood, 123 (22), 3420-3428. doi: 10.1182/blood-2014-03-561456

A Murid gamma-herpesviruses exploits normal splenic immune communication routes for systemic spread

Frederico, B., Chao, B., May, J.S., Belz, G.T. and Stevenson, P.G. (2014). A Murid gamma-herpesviruses exploits normal splenic immune communication routes for systemic spread. Cell Host and Microbe, 15 (4), 457-470. doi: 10.1016/j.chom.2014.03.010

Transcription factor IRF4 regulates germinal center cell formation through a B cell-intrinsic mechanism

Willis, Simon N., Good-Jacobson, Kim L., Curtis, Joan, Light, Amanda, Tellier, Julie, Shi, Wei, Smyth, Gordon K., Tarlinton, David M., Belz, Gabrielle T., Corcoran, Lynn M., Kallies, Axel and Nutt, Stephen L. (2014). Transcription factor IRF4 regulates germinal center cell formation through a B cell-intrinsic mechanism. Journal of Immunology, 192 (7), 3200-3206. doi: 10.4049/jimmunol.1303216

Differential requirement for Nfil3 during NK cell development

Seillet C., Huntington N.D., Gangatirkar P., Axelsson E., Minnich M., Brady H.J.M., Busslinger M., Smyth M.J., Belz G.T. and Carotta S. (2014). Differential requirement for Nfil3 during NK cell development. Journal of Immunology, 192 (6), 2667-2676. doi: 10.4049/jimmunol.1302605

Fas ligand-mediated immune surveillance by T cells is essential for the control of spontaneous B cell lymphomas

Afshar-Sterle, Shoukat, Zotos, Dimitra, Bernard, Nicholas J., Scherger, Anna K., Roedling, Lisa, Alsop, Amber E., Walker, Jennifer, Masson, Frederick, Belz, Gabrielle T., Corcoran, Lynn M., O'Reilly, Lorraine A., Strasser, Andreas, Smyth, Mark J., Johnstone, Ricky, Tarlinton, David M., Nutt, Stephen L. and Kallies, Axel (2014). Fas ligand-mediated immune surveillance by T cells is essential for the control of spontaneous B cell lymphomas. Nature Medicine, 20 (3), 283-290. doi: 10.1038/nm.3442

Erratum: The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells (Nature Immunology (2013) 14 (1155-1165 ))

Man, Kevin, Miasari, Maria, Shi, Wei, Xin, Annie, Henstridge, Darren C., Preston, Simon, Pellegrini, Marc, Belz, Gabrielle T., Smyth, Gordon K., Febbraio, Mark A., Nutt, Stephen L. and Kallies, Axel (2014). Erratum: The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells (Nature Immunology (2013) 14 (1155-1165 )). Nature Immunology, 15 (9), 894-894. doi: 10.1038/ni0914-894b

IL-17-producing NKT cells depend exclusively on IL-7 for homeostasis and survival

Webster, K. E., Kim, H. O., Kyparissoudis, K., Corpuz, T. M., Pinget, G. V., Uldrich, A. P., Brink, R., Belz, G. T., Cho, J. H., Godfrey, D. I. and Sprent, J. (2014). IL-17-producing NKT cells depend exclusively on IL-7 for homeostasis and survival. Mucosal Immunology, 7 (5), 1058-1067. doi: 10.1038/mi.2013.122

Immunology and cell biology publication of the year awards 2013

Belz, Gabrielle (2014). Immunology and cell biology publication of the year awards 2013. Immunology and Cell Biology, 92 (10), 811-812. doi: 10.1038/icb.2014.92

Nfil3 is required for the development of all innate lymphoid cell subsets

Seillet, Cyril, Rankin, Lucille C., Groom, Joanna R., Mielke, Lisa A., Tellier, Julie, Chopin, Michael, Huntington, Nicholas D., Belz, Gabrielle T. and Carotta, Sebastian (2014). Nfil3 is required for the development of all innate lymphoid cell subsets. Journal of Experimental Medicine, 211 (9), 1733-1740. doi: 10.1084/jem.20140145

Suppressor of Cytokine Signaling 4 (SOCS4) protects against severe cytokine storm and enhances viral clearance during influenza infection

Kedzierski, Lukasz, Linossi, Edmond M., Kolesnik, Tatiana B., Day, E. Bridie, Bird, Nicola L., Kile, Benjamin T., Belz, Gabrielle T., Metcalf, Donald, Nicola, Nicos A., Kedzierska, Katherine and Nicholson, Sandra E. (2014). Suppressor of Cytokine Signaling 4 (SOCS4) protects against severe cytokine storm and enhances viral clearance during influenza infection. PLoS Pathogens, 10 (5) e1004134. doi: 10.1371/journal.ppat.1004134

Langerhans cells are generated by two distinct PU.1-dependent transcriptional networks

Chopin, Michaël, Seillet, Cyril, Chevrier, Stéphane, Wu, Li, Wang, Hongsheng, Morse III, Herbert C., Belz, Gabrielle T. and Nutt, Stephen L. (2013). Langerhans cells are generated by two distinct PU.1-dependent transcriptional networks. Journal of Experimental Medicine, 210 (13), 2967-2980. doi: 10.1084/jem.20130930

Circulating precursor CCR7(lo)PD-1(hi) CXCR5(+) CD4(+) T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure

He, Jing, Tsai, Louis M., Leong, Yew Ann, Hu, Xin, Ma, Cindy S., Chevalier, Nina, Sun, Xiaolin, Vandenberg, Kirsten, Rockman, Steve, Ding, Yan, Zhu, Lei, Wei, Wei, Wang, Changqi, Karnowski, Alexander, Belz, Gabrielle T., Ghali, Joanna R., Cook, Matthew C., Riminton, D. Sean, Veillette, Andre, Schwartzberg, Pamela L., Mackay, Fabienne, Brink, Robert, Tangye, Stuart G., Vinuesa, Carola G., Mackay, Charles R., Li, Zhanguo and Yu, Di (2013). Circulating precursor CCR7(lo)PD-1(hi) CXCR5(+) CD4(+) T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure. Immunity, 39 (4), 770-781. doi: 10.1016/j.immuni.2013.09.007

TCF-1 controls ILC2 and NKp46+ RORγt+ innate lymphocyte differentiation and protection in intestinal inflammation

Mielke, Lisa A., Groom, Joanna R., Rankin, Lucille C., Seillet, Cyril, Masson, Frederick, Putoczki, Tracy and Belz, Gabrielle T. (2013). TCF-1 controls ILC2 and NKp46+ RORγt+ innate lymphocyte differentiation and protection in intestinal inflammation. Journal of Immunology, 191 (8), 4383-4391. doi: 10.4049/jimmunol.1301228

The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells

Man, Kevin, Miasari, Maria, Shi, Wei, Xin, Annie, Henstridge, Darren C., Preston, Simon, Pellegrini, Marc, Belz, Gabrielle T., Smyth, Gordon K., Febbraio, Mark A., Nutt, Stephen L. and Kallies, Axel (2013). The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells. Nature Immunology, 14 (11), 1155-1165. doi: 10.1038/ni.2710

Diversity, function, and transcriptional regulation of gut innate lymphocytes

Rankin, Lucille, Groom, Joanna, Mielke, Lisa A., Seillet, Cyril and Belz, Gabrielle T. (2013). Diversity, function, and transcriptional regulation of gut innate lymphocytes. Frontiers in Immunology, 4 (MAR) Article 22. doi: 10.3389/fimmu.2013.00022

Keeping memories alive

Belz, Gabrielle T. and Cretney, Erika (2013). Keeping memories alive. Frontiers in Immunology, 4 (FRB) Article 21. doi: 10.3389/fimmu.2013.00021

Erratum: The transcription factor T-bet is essential for the development of NKp46 + innate lymphocytes via the Notch pathway (Nature Immunology (2013) 14 (389-395))

Rankin, Lucille, Groom, Joanna R., Chopin, Michaël, Herold, Marco J., Walker, Jennifer A., Mielke, Lisa A., Mckenzie, Andrew N. J., Carotta, Sebastian, Nutt, Stephen L. and Belz, Gabrielle T. (2013). Erratum: The transcription factor T-bet is essential for the development of NKp46 + innate lymphocytes via the Notch pathway (Nature Immunology (2013) 14 (389-395)). Nature Immunology, 14 (8), 389-395. doi: 10.1038/ni0813-877b

Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity

Hawkins, Edwin D., Oliaro, Jane, Kallies, Axel, Belz, Gabrielle T., Filby, Andrew, Hogan, Thea, Haynes, Nicole, Ramsbottom, Kelly M., Van Ham, Vanessa, Kinwell, Tanja, Seddon, Benedict, Davies, Derek, Tarlinton, David, Lew, Andrew M., Humbert, Patrick O. and Russell, Sarah M. (2013). Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity. Nature Communications, 4 (1) 1801. doi: 10.1038/ncomms2796

Id2-mediated inhibition of E2A represses memory CD8+ T cell differentiation

Masson, Frederick, Minnich, Martina, Olshansky, Moshe, Bilic, Ivan, Mount, Adele M., Kallies, Axel, Speed, Terence P., Busslinger, Meinrad, Nutt, Stephen L. and Belz, Gabrielle T. (2013). Id2-mediated inhibition of E2A represses memory CD8+ T cell differentiation. Journal of Immunology, 190 (9), 4585-4594. doi: 10.4049/jimmunol.1300099

The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway

Rankin, Lucille C., Groom, Joanna R., Chopin, Michael, Herold, Marco J., Walker, Jennifer A., Mielke, Lisa A., McKenzie, Andrew N. J., Carotta, Sebastian, Nutt, Stephen L. and Belz, Gabrielle T. (2013). The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway. Nature Immunology, 14 (4), 389-395. doi: 10.1038/ni.2545

CD8α+ DCs can be induced in the absence of transcription factors Id2, Nfil3, and Batf3

Seillet, Cyril, Jackson, Jacob T., Markey, Kate A., Brady, Hugh J. M., Hill, Geoffrey R., MacDonald, Kelli P. A., Nutt, Stephen L. and Belz, Gabrielle T. (2013). CD8α+ DCs can be induced in the absence of transcription factors Id2, Nfil3, and Batf3. Blood, 121 (9), 1574-1583. doi: 10.1182/blood-2012-07-445650

MiR-142 keeps CD4+ DCs in balance

Belz, Gabrielle T. (2013). MiR-142 keeps CD4+ DCs in balance. Blood, 121 (6), 871-872. doi: 10.1182/blood-2012-12-472589

Erratum: transcriptional programming of the dendritic cell network (Nature Reviews Immunology (2012) 12 (101-113))

Belz, Gabrielle T. and Nutt, Stephen L. (2013). Erratum: transcriptional programming of the dendritic cell network (Nature Reviews Immunology (2012) 12 (101-113)). Nature Reviews Immunology, 13 (2), 149-149. doi: 10.1038/nri3385

Immunology and Cell Biology Publication of the Year Awards 2012

Belz, Gabrielle (2013). Immunology and Cell Biology Publication of the Year Awards 2012. Immunology and Cell Biology, 91 (10), 595-596. doi: 10.1038/icb.2013.60

Contrôle épigénétique de la stabilité phénotypique et fonctionnelle des lymphocytes Th2 par la voie Suv39h1/HP1a

Zueva, Elina, Allan, Rhys S., Cammas, Florence, Schreiber, Heidi A., Masson, Vanessa, Belz, Gabrielle T., Roche, Danièle, Maison, Christèle, Quivy, Jean-Pierre, Almouzni, Geneviève and Amigorena, Sebastian (2012). Contrôle épigénétique de la stabilité phénotypique et fonctionnelle des lymphocytes Th2 par la voie Suv39h1/HP1a. Medecine/Sciences, 28 (12), 1032-1034. doi: 10.1051/medsci/20122812003

Transcriptional regulation of dendritic cell diversity

Chopin, Michaël, Allan, Rhys S. and Belz, Gabrielle T. (2012). Transcriptional regulation of dendritic cell diversity. Frontiers in Immunology, 3 (FEB) Article 26. doi: 10.3389/fimmu.2012.00026

A new ICB sister journal focuses on clinical and translational immunology

Belz, Gabrielle, Tangye, Stuart G and Liston, Adrian (2012). A new ICB sister journal focuses on clinical and translational immunology. Clinical and Translational Immunology, 1 (11) e1. doi: 10.1038/cti.2012.3

B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1

Karnowski, Alex, Chevrier, Stephane, Belz, Gabrielle T., Mount, Adele, Emslie, Dianne, D'Costa, Kathy, Tarlinton, David M., Kallies, Axel and Corcoran, Lynn M. (2012). B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1. Journal of Experimental Medicine, 209 (11), 2049-2064. doi: 10.1084/jem.20111504

An epigenetic silencing pathway controlling T helper 2 cell lineage commitment

Allan, Rhys S., Zueva, Elina, Cammas, Florence, Schreiber, Heidi A., Masson, Vanessa, Belz, Gabrielle T., Roche, Danièle, Maison, Christèle, Quivy, Jean-Pierre, Almouzni, Geneviève and Amigorena, Sebastian (2012). An epigenetic silencing pathway controlling T helper 2 cell lineage commitment. Nature, 487 (7406), 249-253. doi: 10.1038/nature11173

Unlike CD4+ T-cell help, CD28 costimulation is necessary for effective primary CD8+ T-cell influenza-specific immunity

Seah, Shirley G.K., Carrington, Emma M., Ng, Wy C., Belz, Gabrielle T., Brady, Jamie L., Sutherland, Robyn M., Hancock, Manuela S., La Gruta, Nicole L., Brown, Lorena E., Turner, Stephen J., Zhan, Yifan and Lew, Andrew M. (2012). Unlike CD4+ T-cell help, CD28 costimulation is necessary for effective primary CD8+ T-cell influenza-specific immunity. European Journal of Immunology, 42 (7), 1744-1754. doi: 10.1002/eji.201142211

ISCOMATRIX vaccines mediate CD8 T-cell cross-priming by a MyD88-dependent signaling pathway

Wilson, Nicholas S., Yang, Becky, Morelli, Adriana Baz, Koernig, Sandra, Yang, Annie, Loeser, Stefanie, Airey, Denise, Provan, Larissa, Hass, Phil, Braley, Hal, Couto, Suzana, Drane, Debbie, Boyle, Jeff, Belz, Gabrielle T., Ashkenazi, Avi and Maraskovsky, Eugene (2012). ISCOMATRIX vaccines mediate CD8 T-cell cross-priming by a MyD88-dependent signaling pathway. Immunology and Cell Biology, 90 (5), 540-552. doi: 10.1038/icb.2011.71

The development and fate of follicular helper T cells defined by an IL-21 reporter mouse

Lüthje, Katja, Kallies, Axel, Shimohakamada, Yoko, Belz, Gabrielle T., Light, Amanda, Tarlinton, David M. and Nutt, Stephen L. (2012). The development and fate of follicular helper T cells defined by an IL-21 reporter mouse. Nature Immunology, 13 (5), 491-498. doi: 10.1038/ni.2261

Activated mouse B cells lack expression of granzyme B

Hagn, Magdalena, Belz, Gabrielle T., Kallies, Axel, Sutton, Vivien R., Thia, Kevin Y., Tarlinton, David M., Hawkins, Edwin D. and Trapani, Joseph A. (2012). Activated mouse B cells lack expression of granzyme B. Journal of Immunology, 188 (8), 3886-3892. doi: 10.4049/jimmunol.1103285

Inert 50-nm polystyrene nanoparticles that modify pulmonary dendritic cell function and inhibit allergic airway inflammation

Hardy, Charles L., LeMasurier, Jeanne S., Belz, Gabrielle T., Scalzo-Inguanti, Karen, Yao, Jun, Xiang, Sue D., Kanellakis, Peter, Bobik, Alex, Strickland, Deborah H., Rolland, Jennifer M., O'Hehir, Robyn E. and Plebanski, Magdalena (2012). Inert 50-nm polystyrene nanoparticles that modify pulmonary dendritic cell function and inhibit allergic airway inflammation. Journal of Immunology, 188 (3), 1431-1441. doi: 10.4049/jimmunol.1100156

The NF-κB1 transcription factor prevents the intrathymic development of CD8 T cells with memory properties

Gugasyan, Raffi, Horat, Elisha, Kinkel, Sarah A., Ross, Fiona, Grigoriadis, George, Gray, Daniel, O'Keeffe, Meredith, Berzins, Stuart P., Belz, Gabrielle T., Grumont, Raelene J., Banerjee, Ashish, Strasser, Andreas, Godfrey, Dale I., Tsichlis, Philip N. and Gerondakis, Steve (2012). The NF-κB1 transcription factor prevents the intrathymic development of CD8 T cells with memory properties. EMBO Journal, 31 (3), 692-706. doi: 10.1038/emboj.2011.435

Transcriptional programming of the dendritic cell network

Belz, Gabrielle T. and Nutt, Stephen L. (2012). Transcriptional programming of the dendritic cell network. Nature Reviews Immunology, 12 (2), 101-113. doi: 10.1038/nri3149

Immunology and Cell Biology Publication of the Year Awards 2011

Belz, Gabrielle T. (2012). Immunology and Cell Biology Publication of the Year Awards 2011. Immunology and Cell Biology, 90 (8), 749-750. doi: 10.1038/icb.2012.41

Modeling of influenza-specific CD8 + T cells during the primary response indicates that the spleen is a major source of effectors

Wu, Hulin, Kumar, Arun, Miao, Hongyu, Holden-Wiltse, Jeanne, Mosmann, Timothy R., Livingstone, Alexandra M., Belz, Gabrielle T., Perelson, Alan S., Zand, Martin S. and Topham, David J. (2011). Modeling of influenza-specific CD8 + T cells during the primary response indicates that the spleen is a major source of effectors. Journal of Immunology, 187 (9), 4474-4482. doi: 10.4049/jimmunol.1101443

Murid Herpesvirus-4 Exploits Dendritic Cells to Infect B Cells.

Gaspar, Miguel, May, Janet S., Sukla, Soumi, Frederico, Bruno, Gill, Michael B., Smith, Christopher M., Belz, Gabrielle T. and Stevenson, Philip G. (2011). Murid Herpesvirus-4 Exploits Dendritic Cells to Infect B Cells.. PLoS Pathogens, 7 (11) e1002346, e1002346-e1002346. doi: 10.1371/journal.ppat.1002346

Immunology and Cell Biology publication of the year awards 2010

Belz, Gabrielle T. (2011). Immunology and Cell Biology publication of the year awards 2010. Immunology and Cell Biology, 89 (7), 747-748. doi: 10.1038/icb.2011.77

Id2 expression delineates differential checkpoints in the genetic program of CD8α+ and CD103+ dendritic cell lineages

Jackson, Jacob T., Hu, Yifang, Liu, Ruijie, Masson, Frederick, D'Amico, Angela, Carotta, Sebastian, Xin, Annie, Camilleri, Mary J., Mount, Adele M., Kallies, Axel, Wu, Li, Smyth, Gordon K., Nutt, Stephen L. and Belz, Gabrielle T. (2011). Id2 expression delineates differential checkpoints in the genetic program of CD8α+ and CD103+ dendritic cell lineages. EMBO Journal, 30 (13), 2690-2704. doi: 10.1038/emboj.2011.163

Out-of-the-box thinking

Belz, Gabrielle T. (2011). Out-of-the-box thinking. Immunology and Cell Biology, 89 (5), 575-575. doi: 10.1038/icb.2011.57

Identification of the earliest NK-cell precursor in the mouse BM

Carotta, Sebastian, Pang, Swee Heng Milon, Nutt, Stephen L. and Belz, Gabrielle T. (2011). Identification of the earliest NK-cell precursor in the mouse BM. Blood, 117 (20), 5449-5452. doi: 10.1182/blood-2010-11-318956

The linear range for accurately quantifying antigen-specific T-cell frequencies by tetramer staining during natural immune responses

Seah, Shirley G. K., Sutherland, Robyn M., La Gruta, Nicole L., Brown, Lorena E., Carrington, Emma M., Belz, Gabrielle T., Brady, Jamie L., Turner, Stephen J., Zhan, Yifan and Lew, Andrew M. (2011). The linear range for accurately quantifying antigen-specific T-cell frequencies by tetramer staining during natural immune responses. European Journal of Immunology, 41 (5), 1499-1500. doi: 10.1002/eji.201141399

Diverse roles of inhibitor of differentiation2 in adaptive immunity

Belz, Gabrielle T. and Rankin, Lucille (2011). Diverse roles of inhibitor of differentiation2 in adaptive immunity. Clinical and Developmental Immunology, 2011 281569, 1-11. doi: 10.1155/2011/281569

Bid and Bim collaborate during induction of T cell death in persistent infection

Masson, Frederick, Kupresanin, Fiona, Mount, Adele, Strasser, Andreas and Belz, Gabrielle T. (2011). Bid and Bim collaborate during induction of T cell death in persistent infection. Journal of Immunology, 186 (7), 4059-4066. doi: 10.4049/jimmunol.1001918

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

Cretney, Erika, Xin, Annie, Shi, Wei, Minnich, Martina, Masson, Frederick, Miasari, Maria, Belz, Gabrielle T., Smyth, Gordon K., Busslinger, Meinrad, Nutt, Stephen L. and Kallies, Axel (2011). The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells. Nature Immunology, 12 (4), 304-312. doi: 10.1038/ni.2006

A complementary role for the tetraspanins CD37 and Tssc6 in cellular immunity

Gartlan, Kate H., Belz, Gabrielle T., Tarrant, Jacqueline M., Minigo, Gabriela, Katsara, Maria, Sheng, Kuo-Ching, Sofi, Mariam, van Spriel, Annemiek B., Apostolopoulos, Vasso, Plebanski, Magdalena, Robb, Lorraine and Wright, Mark D. (2010). A complementary role for the tetraspanins CD37 and Tssc6 in cellular immunity. Journal of Immunology, 185 (6), 3158-3166. doi: 10.4049/jimmunol.0902867

Interference with dendritic cell populations limits early antigen presentation in chronic γ-herpesvirus-68 infection

Mount, Adele M., Masson, Frederick, Kupresanin, Fiona, Smith, Christopher M., May, Janet S., Van Rooijen, Nico, Stevenson, Philip G. and Belz, Gabrielle T. (2010). Interference with dendritic cell populations limits early antigen presentation in chronic γ-herpesvirus-68 infection. Journal of Immunology, 185 (6), 3669-3676. doi: 10.4049/jimmunol.1001079

Editorial overview

Belz, Gabrielle T. and Wherry, E John (2010). Editorial overview. Current Opinion in Immunology, 22 (3), 271-273. doi: 10.1016/j.coi.2010.04.007

Effector and memory CD8+ T cell differentiation: toward a molecular understanding of fate determination

Belz, Gabrielle T. and Kallies, Axel (2010). Effector and memory CD8+ T cell differentiation: toward a molecular understanding of fate determination. Current Opinion in Immunology, 22 (3), 279-285. doi: 10.1016/j.coi.2010.03.008

Interleukin-2 tickles T cell memory

Belz, Gabrielle T. and Masson, Frédérick (2010). Interleukin-2 tickles T cell memory. Immunity, 32 (1), 7-9. doi: 10.1016/j.immuni.2010.01.009

Direct ex vivo activation of T cells for analysis of dendritic cells antigen presentation

Belz, Gabrielle T. (2010). Direct ex vivo activation of T cells for analysis of dendritic cells antigen presentation. Methods in Molecular Biology: Dendritic Cell Protocols , 595, 351-369.

Mobilizing forces - CD4+ helper T cells script adaptive immunity

Masson, Frédérick and Belz, Gabrielle T. (2010). Mobilizing forces - CD4+ helper T cells script adaptive immunity. Cell Research, 20 (1), 1-3. doi: 10.1038/cr.2010.1

Mouse models of viral infection: influenza infection in the lung

Mount, Adele M. and Belz, Gabrielle T. (2010). Mouse models of viral infection: influenza infection in the lung. Methods in Molecular Biology, 595, 299-318.

Membrane-bound Fas ligand only is essential for Fas-induced apoptosis

O Reilly, Lorraine A., Tai, Lin, Lee, Lily, Kruse, Elizabeth A., Grabow, Stephanie, Fairlie, W. Douglas, Haynes, Nicole M., Tarlinton, David M., Zhang, Jian-Guo, Belz, Gabrielle T., Smyth, Mark J., Bouillet, Philippe, Robb, Lorraine and Strasser, Andreas (2009). Membrane-bound Fas ligand only is essential for Fas-induced apoptosis. Nature, 461 (7264), 659-663. doi: 10.1038/nature08402

Blimp-1 transcription factor is required for the differentiation of effector CD8+ T cells and memory responses

Kallies, Axel, Xin, Annie, Belz, Gabrielle T. and Nutt, Stephen L. (2009). Blimp-1 transcription factor is required for the differentiation of effector CD8+ T cells and memory responses. Immunity, 31 (2), 283-295. doi: 10.1016/j.immuni.2009.06.021

Life in the balance: Killer T-cell self-control fends off lethal influenza

Belz, Gabrielle T. (2009). Life in the balance: Killer T-cell self-control fends off lethal influenza. Immunology and Cell Biology, 87 (5), 364-365. doi: 10.1038/icb.2009.22

Dendritic cells in viral infections

Belz, Gabrielle, Mount, Adele and Masson, Frederick (2009). Dendritic cells in viral infections. Handbook of Experimental Pharmacology, 188, 51-77. doi: 10.1007/978-3-540-71029-5-3

The tapestry of the immune response for protective immunity

Belz, Gabrielle (2009). The tapestry of the immune response for protective immunity. Human Vaccines, 5 (2), 50-52. doi: 10.4161/hv.5.2.7841

Tissue destruction caused by cytotoxic T lymphocytes induces deletional tolerance

Parish, Ian A., Waithman, Jason, Davey, Gayle M., Belz, Gabrielle T., Mintern, Justine D., Kurts, Christian, Sutherland, Robyn M., Carbone, Francis R. and Heath, William R. (2009). Tissue destruction caused by cytotoxic T lymphocytes induces deletional tolerance. Proceedings of the National Academy of Sciences of the United States of America, 106 (10), 3901-3906. doi: 10.1073/pnas.0810427106

Selected toll-like receptor ligands and viruses promote helper-independent cytotoxic T cell priming by upregulating CD40L on dendritic cells

Johnson, Susan, Zhan, Yifan, Sutherland, Robyn M., Mount, Adele M., Bedoui, Sammy, Brady, Jamie L., Carrington, Emma M., Brown, Lorena E., Belz, Gabrielle T., Heath, William R. and Lew, Andrew M. (2009). Selected toll-like receptor ligands and viruses promote helper-independent cytotoxic T cell priming by upregulating CD40L on dendritic cells. Immunity, 30 (2), 218-227. doi: 10.1016/j.immuni.2008.11.015

The race between infection and immunity: how do pathogens set the pace?

Davenport, Miles P., Belz, Gabrielle T. and Ribeiro, Ruy M. (2009). The race between infection and immunity: how do pathogens set the pace?. Trends in Immunology, 30 (2), 61-66. doi: 10.1016/j.it.2008.11.001

Kinetics of major histocompatibility class I antigen presentation in acute infection

Lay, Matthew D. H., Zhang, Lei, Ribeiro, Ruy M., Mueller, Scott N., Belz, Gabrielle T. and Davenport, Miles P. (2009). Kinetics of major histocompatibility class I antigen presentation in acute infection. Journal of Immunology, 182 (2), 902-911. doi: 10.4049/jimmunol.182.2.902

Differential MHC class II synthesis and ubiquitination confers distinct antigen-presenting properties on conventional and plasmacytoid dendritic cells

Young, Louise J., Wilson, Nicholas S., Schnorrer, Petra, Proietto, Anna, ten Broeke, Toine, Matsuki, Yohei, Mount, Adele M., Belz, Gabrielle T., O'Keeffe, Meredith, Ohmura-Hoshino, Mari, Ishido, Satoshi, Stoorvogel, Willem, Heath, William R., Shortman, Ken and Villadangos, Jose A. (2008). Differential MHC class II synthesis and ubiquitination confers distinct antigen-presenting properties on conventional and plasmacytoid dendritic cells. Nature Immunology, 9 (11), 1244-1252. doi: 10.1038/ni.1665

Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8α+ dendritic cells

Lundie, Rachel J., De Koning-Ward, Tania F., Davey, Gayle M., Nie, Catherine Q., Hansen, Diana S., Lei, Shong Lau, Mintern, Justine D., Belz, Gabrielle T., Schofield, Louis, Carbone, Francis R., Villadangos, Jose A., Crabb, Brendan S. and Heath, William R. (2008). Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8α+ dendritic cells. Proceedings of the National Academy of Sciences of the United States of America, 105 (38), 14509-14514. doi: 10.1073/pnas.0806727105

DC migration: hard-wired for T cell activation

Belz, Gabrielle T. (2008). DC migration: hard-wired for T cell activation. Immunity, 29 (3), 388-390. doi: 10.1016/j.immuni.2008.08.003

Dendritic cells: driving the differentiation programme of T cells in viral infections

Masson, Frederick, Mount, Adele M., Wilson, Nicholas S. and Belz, Gabrielle T. (2008). Dendritic cells: driving the differentiation programme of T cells in viral infections. Immunology and Cell Biology, 86 (4), 333-342. doi: 10.1038/icb.2008.15

Getting together: dendritic cells, T cells, collaboration and fates

Belz, Gabrielle T. (2008). Getting together: dendritic cells, T cells, collaboration and fates. Immunology and Cell Biology, 86 (4), 310-311. doi: 10.1038/icb.2008.18

Blimp-1 connects the intrinsic and extrinsic regulation of T cell homeostasis

Nutt, Stephen L., Kallies, Axel and Belz, Gabrielle T. (2008). Blimp-1 connects the intrinsic and extrinsic regulation of T cell homeostasis. Journal of Clinical Immunology, 28 (2), 97-106. doi: 10.1007/s10875-007-9151-6

Multiple dendritic cell populations activate CD4+ T cells after viral stimulation

Mount, Adele M., Smith, Christopher M., Kupresanin, Fiona, Stoermer, Kristina, Heath, William R. and Belz, Gabrielle T. (2008). Multiple dendritic cell populations activate CD4+ T cells after viral stimulation. PLoS One, 3 (2) e1691, e1691. doi: 10.1371/journal.pone.0001691

BH3-only protein Puma contributes to death of antigen-specific T cells during shutdown of an immune response to acute viral infection

Fischer, Silke F., Belz, Gabrielle T. and Strasser, Andreas (2008). BH3-only protein Puma contributes to death of antigen-specific T cells during shutdown of an immune response to acute viral infection. Proceedings of the National Academy of Sciences of the United States of America, 105 (8), 3035-3040. doi: 10.1073/pnas.0706913105

Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity

Hughes, Peter D., Belz, Gabrielle T., Fortner, Karen A., Budd, Ralph C., Strasser, Andreas and Bouillet, Philippe (2008). Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity. Immunity, 28 (2), 197-205. doi: 10.1016/j.immuni.2007.12.017

Normal proportion and expression of maturation markers in migratory dendritic cells in the absence of germs or Toll-like receptor signaling

Wilson, Nicholas S., Young, Louise J., Kupresanin, Fiona, Naik, Shalin H., Vremec, David, Heath, William R., Akira, Shizuo, Shortman, Ken, Boyle, Jeff, Maraskovsky, Eugene, Belz, Gabrielle T. and Villadangos, José A. (2008). Normal proportion and expression of maturation markers in migratory dendritic cells in the absence of germs or Toll-like receptor signaling. Immunology and Cell Biology, 86 (2), 200-205. doi: 10.1038/sj.icb.7100125

Dendritic cells present lytic antigens and maintain function throughout persistent gamma-herpesvirus infection

Kupresanin, Fiona, Chow, Jonathan, Mount, Adele, Smith, Christopher M., Stevenson, Philip G. and Belz, Gabrielle T. (2007). Dendritic cells present lytic antigens and maintain function throughout persistent gamma-herpesvirus infection. Journal of Immunology, 179 (11), 7506-7513. doi: 10.4049/jimmunol.179.11.7506

Minimal activation of memory CD8+ T cell by tissue-derived dendritic cells favors the stimulation of naive CD8+ T cells

Belz, Gabrielle T., Bedoui, Sammy, Kupresanin, Fiona, Carbone, Francis R. and Heath, William R. (2007). Minimal activation of memory CD8+ T cell by tissue-derived dendritic cells favors the stimulation of naive CD8+ T cells. Nature Immunology, 8 (10), 1060-1066. doi: 10.1038/ni1505

Skin-derived dendritic cells can mediate deletional tolerance of class I-restricted self-reactive T cells

Waithman, Jason, Allan, Rhys S., Kosaka, Hiroshi, Azukizawa, Hiroaki, Shortman, Ken, Lutz, Manfred B., Heath, William R., Carbone, Francis R. and Belz, Gabrielle T. (2007). Skin-derived dendritic cells can mediate deletional tolerance of class I-restricted self-reactive T cells. Journal of Immunology, 179 (7), 4535-4541. doi: 10.4049/jimmunol.179.7.4535

A role for plasmacytoid dendritic cells in the rapid IL-18-dependent activation of NK cells following HSV-1 infection

Barr, Daniel P., Belz, Gabrielle T., Reading, Patrick C., Wojtasiak, Magdalena, Whitney, Paul G., Heath, William R., Carbone, Francis R. and Brooks, Andrew G. (2007). A role for plasmacytoid dendritic cells in the rapid IL-18-dependent activation of NK cells following HSV-1 infection. European Journal of Immunology, 37 (5), 1334-1342. doi: 10.1002/eji.200636362

Killer T cells regulate antigen presentation for early expansion of memory, but not naive, CD8+ T cell

Belz, Gabrielle T., Zhang, Lei, Lay, Matthew D. H., Kupresanin, Fiona and Davenport, Miles P. (2007). Killer T cells regulate antigen presentation for early expansion of memory, but not naive, CD8+ T cell. Proceedings of the National Academy of Sciences of the United States of America, 104 (15), 6341-6346. doi: 10.1073/pnas.0609990104

CD4+ T cells specific for a model latency-associated antigen fail to control a gammaherpesvirus in vivo

Smith, Christopher M., Rosa, Gustavo T. L., May, Janet S., Bennett, Neil J., Mouni, Adele M., Belz, Gabrielle T. and Stevenson, Philip G. (2006). CD4+ T cells specific for a model latency-associated antigen fail to control a gammaherpesvirus in vivo. European Journal of Immunology, 36 (12), 3186-3197. doi: 10.1002/eji.200636164

The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen capture

Schnorrer, Petra, Behrens, Georg M. N., Wilson, Nicholas S., Pooley, Joanne L., Smith, Christopher M., El-Sukkari, Dima, Davey, Gayle, Kupresanin, Fiona, Li, Ming, Maraskovsky, Eugene, Belz, Gabrielle T., Carbone, Francis R., Shortman, Ken, Heath, William R. and Villadangos, Jose A. (2006). The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen capture. Proceedings of the National Academy of Sciences of the United States of America, 103 (28), 10729-10734. doi: 10.1073/pnas.0601956103

Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance

Kallies, Axel, Hawkins, Edwin D., Belz, Gabrielle T., Metcalf, Donald, Hommel, Mirja, Corcoran, Lynn M., Hodgkin, Philip D. and Nutt, Stephen L. (2006). Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance. Nature Immunology, 7 (5), 466-474. doi: 10.1038/ni1321

Bone marrow-derived cells expand memory CD8+ T cells in response to viral infections of the lung and skin

Belz, Gabrielle T., Wilson, Nicholas S., Smith, Christopher M., Mount, Adele M., Carbone, Francis R. and Heath, William R. (2006). Bone marrow-derived cells expand memory CD8+ T cells in response to viral infections of the lung and skin. European Journal of Immunology, 36 (2), 327-335. doi: 10.1002/eji.200535432

Systemic activation of dendritic cells by Toll-like receptor ligands or malaria infection impairs cross-presentation and anti-viral immunity

Wilson, Nicholas S., Behrens, Georg M. N., Lundie, Rachel J., Smith, Christopher M., Waithman, Jason, Young, Louise, Forehan, Simon P., Mount, Adele, Steptoe, Raymond J., Shortman, Ken D., de Koning-Ward, Tania F, Belz, Gabrielle T., Carbone, Francis R ., Crabb, Brendan S., Heath, William R. and Villadangos, Jose A. (2006). Systemic activation of dendritic cells by Toll-like receptor ligands or malaria infection impairs cross-presentation and anti-viral immunity. Nature Immunology, 7 (2), 165-172. doi: 10.1038/ni1300

CD8α+ dendritic cells selectively present MHC class I-restricted noncytolytic viral and intracellular bacterial antigens in vivo

Belz, Gabrielle T., Shortman, Ken, Bevan, Michael J. and Heath, William R. (2005). CD8α+ dendritic cells selectively present MHC class I-restricted noncytolytic viral and intracellular bacterial antigens in vivo. Journal of Immunology, 175 (1), 196-200. doi: 10.4049/jimmunol.175.1.196

Cognate CD4+ T cell licensing of dendritic cells in CD8+ T cell immunity

Smith, Christopher M., Wilson, Nicholas S., Waithman, Jason, Villadangos, Jose A., Carbone, Francis R., Heath, William R. and Belz, Gabrielle T. (2004). Cognate CD4+ T cell licensing of dendritic cells in CD8+ T cell immunity. Nature Immunology, 5 (11), 1143-1148. doi: 10.1038/ni1129

Loss of Bim increases T cell production and function in interleukin 7 receptor-deficient mice

Pellegrini, Marc, Bouillet, Philippe, Robati, Mikara, Belz, Gabrielle T., Davey, Gayle M. and Strasser, Andreas (2004). Loss of Bim increases T cell production and function in interleukin 7 receptor-deficient mice. Journal of Experimental Medicine, 200 (9), 1189-1195. doi: 10.1084/jem.20041328

Distinct migrating and nonmigrating dendritic cell population are involved in MHC class I-restricted antigen presentation after lung infection with virus

Belz, Gabrielle T., Smith, Christopher M., Kleinert, Lauren, Reading, Patrick, Brooks, Andrew, Shortman, Ken, Carbone, Francis R. and Heath, William R. (2004). Distinct migrating and nonmigrating dendritic cell population are involved in MHC class I-restricted antigen presentation after lung infection with virus. Proceedings of the National Academy of Sciences of the United States of America, 101 (23), 8670-8675. doi: 10.1073/pnas.0402644101

Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens

Heath, William R., Belz, Gabrielle T., Behrens, Georg M. N., Smith, Christopher M., Forehan, Simon P., Parish, Ian A., Davey, Gayle M., Wilson, Nicholas S., Carbone, Francis R. and Villadangos, Jose A. (2004). Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens. Immunological Reviews, 199 (1), 9-26. doi: 10.1111/j.0105-2896.2004.00142.x

DCs as targets for vaccine design

Belz, Gabrielle T., Smith, C. M., Bharadwaj, M., Rice, A. M. and Jackson, D. C. (2004). DCs as targets for vaccine design. Cytotherapy, 6 (2), 88-98. doi: 10.1080/14653240410005276

Cutting edge: Conventional CD8α+ dendritic cells are generally involved in priming CTL immunity to viruses

Belz, Gabrielle T., Smith, Christopher M., Eichner, Daniel, Shortman, Ken, Karupiah, Guna, Carbone, Francis R. and Heath, William R. (2004). Cutting edge: Conventional CD8α+ dendritic cells are generally involved in priming CTL immunity to viruses. Journal of Immunology, 172 (4), 1996-2000.

Helper T cells, dendritic cells and CTL immunity

Behrens, Georg, Li, Ming, Smith, Christopher M., Belz, Gabrielle T., Mintern, Justine, Carbone, Francis R. and Heath, William R. (2004). Helper T cells, dendritic cells and CTL immunity. Immunology and Cell Biology, 82 (1), 84-90. doi: 10.1111/j.1440-1711.2004.01211.x

Transfer of antigen between migrating and lymph node-resident DCs in peripheral T-cell tolerance and immunity

Carbone, Francis R., Belz, Gabrielle T. and Heath, William R. (2004). Transfer of antigen between migrating and lymph node-resident DCs in peripheral T-cell tolerance and immunity. Trends in Immunology, 25 (12), 655-658. doi: 10.1016/j.it.2004.09.013

Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim

Pellegrini, Marc, Belz, Gabrielle, Bouillet, Philippe and Strasser, Andreas (2003). Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim. Proceedings of the National Academy of Sciences of the United States of America, 100 (24), 14175-14180. doi: 10.1073/pnas.2336198100

Epidermal viral immunity induced by CD8α+ dendritic cells but not by langerhans cells

Allan, Rhys S., Smith, Chris M., Belz, Gabrielle T., Van Lint, Allison L., Wakim, Linda M., Heath, William R. and Carbone, Francis R. (2003). Epidermal viral immunity induced by CD8α+ dendritic cells but not by langerhans cells. Science, 301 (5641), 1925-1928. doi: 10.1126/science.1087576

Most lymphoid organ dendritic cell types are phenotypically and functionally immature

Wilson, Nicholas S., El-Sukkari, Dima, Belz, Gabrielle T., Smith, Christopher M., Steptoe, Raymond J., Heath, William R., Shortman, Ken and Villadangos, José A. (2003). Most lymphoid organ dendritic cell types are phenotypically and functionally immature. Blood, 102 (6), 2187-2194. doi: 10.1182/blood-2003-02-0513

Cutting edge: Conventional CD8α+ dendritic cells are preferentially involved in CTL priming after footpad infection with herpes simplex virus-1

Smith, Christopher M., Belz, Gabrielle T., Wilson, Nicholas S., Villadangos, Jose A., Shortman, Ken, Carbone, Francis R. and Heath, William R. (2003). Cutting edge: Conventional CD8α+ dendritic cells are preferentially involved in CTL priming after footpad infection with herpes simplex virus-1. Journal of Immunology, 170 (9), 4437-4440.

Absence of functional defect in CD8+ T cells during primary murine gammaherpesvirus-68 infection of I-Ab-/- mice

Belz, Gabrielle T., Liu, Haiyan, Andreansky, Samita, Doherty, Peter C. and Stevenson, Philip G. (2003). Absence of functional defect in CD8+ T cells during primary murine gammaherpesvirus-68 infection of I-Ab-/- mice. Journal of General Virology, 84 (2), 337-341. doi: 10.1099/vir.0.18821-0

Compromised influenza virus-specific CD8+-T-cell memory in CD4+-T-cell-deficient mice

Belz, Gabrielle T., Wodarz, Dominik, Diaz, Gabriela, Nowak, Martin A. and Doherty, Peter C. (2002). Compromised influenza virus-specific CD8+-T-cell memory in CD4+-T-cell-deficient mice. Journal of Virology, 76 (23), 12388-12393. doi: 10.1128/JVI.76.23.12388-12393.2002

Cross-presentation of antigens by dendritic cells

Belz, Gabrielle T., Carbone, Francis R. and Heath, William R. (2002). Cross-presentation of antigens by dendritic cells. Critical Reviews in Immunology, 22 (5-6), 439-448.

The CD8α+ dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens

Belz, Gabrielle T., Behrens, Georg M. N., Smith, Chris M., Miller, Jacques F. A. P., Jones, Claerwen, Lejon, Kristina, Garrison Fathman, C., Mueller, Scott N., Shortman, Ken, Carbone, Francis R. and Heath, William R. (2002). The CD8α+ dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens. Journal of Experimental Medicine, 196 (8), 1099-1104. doi: 10.1084/jem.20020861

The role of dendritic cell subsets in selection between tolerance and immunity

Belz, G. T., Heath, W. R. and Carbone, F. R. (2002). The role of dendritic cell subsets in selection between tolerance and immunity. Immunology and Cell Biology, 80 (5), 463-468. doi: 10.1046/j.1440-1711.2002.01116.x

CD36 is differentially expressed by CD8+ splenic dendritic cells but is not required for cross-presentation in vivo

Belz, Gabrielle T., Vremec, David, Febbraio, Maria, Corcoran, Lynn, Shortman, Ken, Carbone, Francis R. and Heath, William R. (2002). CD36 is differentially expressed by CD8+ splenic dendritic cells but is not required for cross-presentation in vivo. Journal of Immunology, 168 (12), 6066-6070. doi: 10.4049/jimmunol.168.12.6066

The cross-priming APC requires a rel-dependent signal to induce CTL

Mintern, Justine D., Belz, Gabrielle, Gerondakis, Steve, Carbone, Francis R. and Heath, William R. (2002). The cross-priming APC requires a rel-dependent signal to induce CTL. Journal of Immunology, 168 (7), 3283-3287. doi: 10.4049/jimmunol.168.7.3283

Cutting edge: precursor frequency affects the helper dependence of cytotoxic T cells

Mintern, Justine D., Davey, Gayle M., Belz, Gabrielle T., Carbone, Francis R. and Heath, William R. (2002). Cutting edge: precursor frequency affects the helper dependence of cytotoxic T cells. Journal of Immunology, 168 (3), 977-980. doi: 10.4049/jimmunol.168.3.977

The role of antigen in the localization of naive, acutely activated, and memory CD8+ T cells to the lung during influenza pneumonia

Topham, D. J., Castrucci, M. R., Wingo, F. S., Belz, G. T. and Doherty, P. C. (2001). The role of antigen in the localization of naive, acutely activated, and memory CD8+ T cells to the lung during influenza pneumonia. Journal of Immunology, 167 (12), 6983-6990. doi: 10.4049/jimmunol.167.12.6983

Erratum: Diversity of epitope and cytokine profiles for primary and secondary influenza A virus-specific CD8+ T cell responses (Journal of Immunology (2001) 166 (4627-4633))

Belz, G. T., Xie, W. and Doherty, P. C. (2001). Erratum: Diversity of epitope and cytokine profiles for primary and secondary influenza A virus-specific CD8+ T cell responses (Journal of Immunology (2001) 166 (4627-4633)). Journal of Immunology, 167 (3)

Viral neuraminidase treatment of dendritic cells enhances antigen-specific CD8+ T cell proliferation, but does not account for the CD4+ T cell independence of the CD8+ T cell response during influenza virus infection

Oh, SangKon, Belz, Gabrielle T. and Eichelberger, Maryna C. (2001). Viral neuraminidase treatment of dendritic cells enhances antigen-specific CD8+ T cell proliferation, but does not account for the CD4+ T cell independence of the CD8+ T cell response during influenza virus infection. Virology, 286 (2), 403-411. doi: 10.1006/viro.2001.0992

Measuring the diaspora for virus-specific CD8+ T cells

Marshall, Dana R., Turner, Stephen J., Belz, Gabrielle T., Wingo, Suzette, Andreansky, Samita, Sangster, Mark Y., Riberdy, Janice M., Liu, Tiebin, Tan, Ming and Doherty, Peter C. (2001). Measuring the diaspora for virus-specific CD8+ T cells. Proceedings of the National Academy of Sciences of the United States of America, 98 (11), 6313-6318. doi: 10.1073/pnas.101132698

Virus-specific and bystander CD8+ T-cell proliferation in the acute and persistent phases of a gammaherpesvirus infection

Belz, G. T. and Doherty, P. C. (2001). Virus-specific and bystander CD8+ T-cell proliferation in the acute and persistent phases of a gammaherpesvirus infection. Journal of Virology, 75 (9), 4435-4438. doi: 10.1128/JVI.75.9.4435-4438.2001

Dissecting the host response to a gamma-herpesvirus

Doherty, P.C., Christensen, J.P., Belz, G.T., Stevenson, P.G. and Sangster, M.Y. (2001). Dissecting the host response to a gamma-herpesvirus. Philosophical Transactions of the Royal Society B-Biological Sciences, 356 (1408), 581-593. doi: 10.1098/rstb.2000.0786

Diversity of epitope and cytokine profiles for primary and secondary influenza A virus-specific CD8+ T cell responses

Belz, G. T., Xie, W. and Doherty, P. C. (2001). Diversity of epitope and cytokine profiles for primary and secondary influenza A virus-specific CD8+ T cell responses. Journal of Immunology, 166 (7), 4627-4633. doi: 10.4049/jimmunol.166.7.4627

Perforin and Fas in murine gammaherpesvirus-specific CD8+ T cell control and morbidity

Topham, D. J., Cardin, R. C., Christensen, J. P., Brooks, J. W., Belz, G. T. and Doherty, P. C. (2001). Perforin and Fas in murine gammaherpesvirus-specific CD8+ T cell control and morbidity. Journal of General Virology, 82 (8), 1971-1981. doi: 10.1099/0022-1317-82-8-1971

Contemporary analysis of MHC-related immunodominance hierarchies in the CD8(+) T cell response to influenza A viruses

Belz, G.T., Stevenson, P.G. and Doherty, P.C. (2000). Contemporary analysis of MHC-related immunodominance hierarchies in the CD8(+) T cell response to influenza A viruses. Journal of Immunology, 165 (5), 2404-2409. doi: 10.4049/jimmunol.165.5.2404

Quantitative analysis of the CD8+ T-cell response to readily eliminated and persistent viruses

Doherty, P. C., Riberdy, J. M. and Belz, G. T. (2000). Quantitative analysis of the CD8+ T-cell response to readily eliminated and persistent viruses. Philosophical Transactions of the Royal Society B: Biological Sciences, 355 (1400), 1093-1101. doi: 10.1098/rstb.2000.0647

A previously unrecognized H-2Db-restricted peptide prominent in the primary influenza a virus-specific CD8+ T-cell response is much less apparent following secondary challenge

Belz, Gabrielle T., Xie, Weidong, Altman, John D. and Doherty, Peter C. (2000). A previously unrecognized H-2Db-restricted peptide prominent in the primary influenza a virus-specific CD8+ T-cell response is much less apparent following secondary challenge. Journal of Virology, 74 (8), 3486-3493. doi: 10.1128/JVI.74.8.3486-3493.2000

Postexposure vaccination massively increases the prevalence of γ- herpesvirus-specific CD8+ T cells but confers minimal survival advantage on CD4-deficient mice

Belz, G.T., Stevenson, P.G., Castrucci, M.R., Altman, J.D. and Doherty, P.C. (2000). Postexposure vaccination massively increases the prevalence of γ- herpesvirus-specific CD8+ T cells but confers minimal survival advantage on CD4-deficient mice. Proceedings of the National Academy of Sciences of the United States of America, 97 (6), 2725-2730. doi: 10.1073/pnas.040575197

A γ-herpesvirus sneaks through a CD8+ T cell response primed to a lytic-phase epitope

Stevenson, P.G., Belz, G.T., Castrucci, M.R., Altman, J.D. and Doherty, P.C. (1999). A γ-herpesvirus sneaks through a CD8+ T cell response primed to a lytic-phase epitope. Proceedings of the National Academy of Sciences of the United States of America, 96 (16), 9281-9286. doi: 10.1073/pnas.96.16.9281

Changing patterns of dominance in the CD8(+) T cell response during acute and persistent murine gamma-herpesvirus infection

Stevenson, P.G., Belz, G.T., Altman, J.D. and Doherty, P.C. (1999). Changing patterns of dominance in the CD8(+) T cell response during acute and persistent murine gamma-herpesvirus infection. European Journal of Immunology, 29 (4), 1059-1067. doi: 10.1002/(SICI)1521-4141(199904)29:04<1059::AID-IMMU1059>3.0.CO;2-L

Characteristics of virus-specific CD8+ T cells in the liver during the control and resolution phases of influenza pneumonia

Belz, Gabrielle T., Altman, John D. and Doherty, Peter C. (1998). Characteristics of virus-specific CD8+ T cells in the liver during the control and resolution phases of influenza pneumonia. Proceedings of the National Academy of Sciences of the United States of America, 95 (23), 13812-13817. doi: 10.1073/pnas.95.23.13812

Intercellular and lymphatic pathways associated with tonsils of the soft palate in young pigs

Belz, Gabrielle T. (1998). Intercellular and lymphatic pathways associated with tonsils of the soft palate in young pigs. Anatomy and Embryology, 197 (4), 331-340. doi: 10.1007/s004290050143

An unusual structure of venules in tonsils of the soft palate of young pigs

Belz, Gabrielle T. (1998). An unusual structure of venules in tonsils of the soft palate of young pigs. Journal of Anatomy, 192 (1), 131-135. doi: 10.1017/S0021878297002975

The continuing revolution in virus-specific CD8+ T cell-mediated immunity

Doherty, P. C., Belz, G. T. and Flynn, K. J. (1998). The continuing revolution in virus-specific CD8+ T cell-mediated immunity. Immunologist, 6 (5), 173-177.

Virus-specific CD8+ T cell numbers are maintained during γ- herpesvirus reactivation in CD4-deficient mice

Stevenson, P.G., Belz, G.T., Altman, J.D. and Doherty, P.C. (1998). Virus-specific CD8+ T cell numbers are maintained during γ- herpesvirus reactivation in CD4-deficient mice. Proceedings of the National Academy of Sciences of the United States of America, 95 (26), 15565-15570. doi: 10.1073/pnas.95.26.15565

Virus-specific CD8+ T cells in primary and secondary influenza pneumonia

Flynn, Kirsten J., Belz, Gabrielle T., Altman, John D., Ahmed, Rafi, Woodland, David L. and Doherty, Peter C. (1998). Virus-specific CD8+ T cells in primary and secondary influenza pneumonia. Immunity, 8 (6), 683-691. doi: 10.1016/S1074-7613(00)80573-7

Tonsils of the soft palate of young pigs: Crypt structure and lymphoepithelium

Belz G.T. and Heath T.J. (1996). Tonsils of the soft palate of young pigs: Crypt structure and lymphoepithelium. Anatomical Record, 245 (1), 102-113. doi: 10.1002/(SICI)1097-0185(199605)245:1<102::AID-AR15>3.0.CO;2-T

An investigation of the use of chromium, platinum and gold coating for scanning electron-microscopy of casts of lymphoid-tissues

Belz, G.T. and Auchterlonie, G.J. (1995). An investigation of the use of chromium, platinum and gold coating for scanning electron-microscopy of casts of lymphoid-tissues. Micron, 26 (2), 141-144. doi: 10.1016/0968-4328(95)00055-9

Intercellular and lymphatic pathways of the canine palatine tonsils

Belz, G. T. and Heath, T. J. (1995). Intercellular and lymphatic pathways of the canine palatine tonsils. Journal of Anatomy, 187 (1), 93-105.

Lymph pathways of the medial retropharyngeal lymph node in dogs

Belz, G. T. and Heath, T. J. (1995). Lymph pathways of the medial retropharyngeal lymph node in dogs. Journal of Anatomy, 186 (3), 517-526.

Lymphatic drainage from the tonsil of the soft palate in pigs

Belz, G.T. and Heath, T.J. (1995). Lymphatic drainage from the tonsil of the soft palate in pigs. Journal of Anatomy, 187 (2), 491-495.

Pathways of blood flow to and through superficial lymph nodes in the dog

Belz, G. T. and Heath, T. J. (1995). Pathways of blood flow to and through superficial lymph nodes in the dog. Journal of Anatomy, 187 (2), 413-421.

The epithelium of canine palatine tonsils

Belz, G.T. and Heath, T.J. (1995). The epithelium of canine palatine tonsils. Anatomy and Embryology, 192 (2), 189-194. doi: 10.1007/BF00186007

Deep single-cell, proteogenomic insights from SARS-CoV-2 infected lung tissues

Kulasinghe, Arutha, Tan, Chin Wee, Liu, Ning, Monkman, James, Killingbeck, Emily, Kim, Youngmi, Pan, Liuliu, Blick, Tony, Bhuva, Dharmesh, Feher, Kristen, Leon, Michael, Gregory, Mark, Short, Kirsty, Guimaraes, Fernando, Rhodes, Michael, Belz, Gabrielle and Davis, Melissa (2022). Deep single-cell, proteogenomic insights from SARS-CoV-2 infected lung tissues. SITC 37th Annual Meeting (SITC 2022), Boston, MA USA, 8-12 November 2022. London, United Kingdom: BMJ Publishing Group. doi: 10.1136/jitc-2022-sitc2022.0923

High-dimensional spatial phenotyping of cutaneous squamous cell carcinoma from immune-competent and immunocompromised patients

Kulasinghe, Arutha, Jhaveri, Niyati, Klymyshyn, Dmytro, Cheikh, Bassem Ben, Ladwa, Rahul, Liu, Howard, Cooper, Caroline, Belz, Gabrielle, Porceddu, Sandro and Braubach, Oliver (2022). High-dimensional spatial phenotyping of cutaneous squamous cell carcinoma from immune-competent and immunocompromised patients. SITC 37th Annual Meeting (SITC 2022), Boston, MA United States, 8–12 November 2022. London, United Kingdom: BMJ Group. doi: 10.1136/jitc-2022-sitc2022.0079

4th Australasian vaccines and immunotherapeutic development meeting

Engwerda, Christian and Belz, Gabrielle (2012). 4th Australasian vaccines and immunotherapeutic development meeting. 4th Australasian vaccines and immunotherapeutic development meeting, Oxford, United Kingdom: John Wiley & Sons. doi: 10.1038/icb.2012.55

Blimp1: Driving terminal differentiation to a T

Xin, Annie, Nutt, Stephen L., Belz, Gabrielle T. and Kallies, Axel (2011). Blimp1: Driving terminal differentiation to a T. Aegean Conference: 3rd Crossroads between innate and adaptive immunity, Chania, Crete, Greece, 27 September - October 2, 2009. New York, NY, United States: Springer. doi: 10.1007/978-1-4419-5632-3_8

The Sir Mark Oliphant conferences: International frontiers of science and technology

Belz, Gabrielle T. and De Groot, Annie (2008). The Sir Mark Oliphant conferences: International frontiers of science and technology. Vaccines and Immunotherapy Technologies Conference, Canberra, ACT, Australia, 9-11 April 2008. Landes Bioscience. doi: 10.4161/hv.4.4.6334

Discussion

Belz, Gabrielle, Britton, Warwick J., Casanova, Jean-Laurent, Foote, Simon, Goodnow, Christopher C., Gros, Philippe, Hume, David, Maizels, Rick M. and Turner, Stephen (2007). Discussion. Symposium on Cortical development: genes and genetic abnormalities, London, United Kingdom, 6–8 February 2007. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

Discussion

Alexander, Warren S., Belz, Gabrielle, Britton, Warwick J., Cook, Matthew, Cyster, Jason, Goodnow, Christopher C., Hume, David, Kaufman, Jim, Mackay, Charles, Stacker, Steven and Turner, Stephen (2007). Discussion. Symposium on Cortical development: genes and genetic abnormalities, London, United Kingdom, 6–8 February 2007. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

Shaping naive and memory Cd8+ T cell responses in pathogen infections through antigen presentation

Belz, Gabrielle T., Wilson, Nicholas S., Kupresanin, Fiona, Mount, Adele M. and Smith, Christopher M. (2007). Shaping naive and memory Cd8+ T cell responses in pathogen infections through antigen presentation. First Crossroads between Innate and Adaptive Immunity, Rhodes, Greece, October 9–14, 2005 . Boston, MA, United States: Springer. doi: 10.1007/978-0-387-34814-8_2

Most lymphoid organ dendritic cell types are phenotypically and functionally immature

Wilson, N.S., Villadangos, J.A., El-Sukkari, D. and Belz, G.T. (2003). Most lymphoid organ dendritic cell types are phenotypically and functionally immature. 8th International Workshop on Langerhans Cells, Tokyo, Japan, 5-7 September 2003. Oxford, United Kingdom: Elsevier.