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Professor Sunil Lakhani

Conjoint Professorial Res Fellow

UQ Centre for Clinical Research
Faculty of Medicine
s.lakhani@uq.edu.au
+61 7 334 66052

Overview

Sunil Lakhani is Executive Director Research and Senior Staff Specialist, Pathology Queensland, and Head of the Molecular Breast Group at the University of Queensland Centre for Clinical Research (UQCCR) at the Royal Brisbane and Women’s Hospital.

Prior to his move to Australia in 2004, he was Professor of Breast Pathology at The Institute of Cancer Research and The Royal Marsden Hospital, London, UK

His current research interests include lobular carcinoma and its variants, normal and stem cells, tumours with a basal phenotype, familial breast cancer and biology and therapeutic development for brain and distant metastases.

He was series editor for the 4th Edition WHO Tumour Classification Books and volume editor for the 4th Ed WHO Classification of Tumours of the Breast (2012). He is currently Standing member of the Board for the 5th Ed WHO Tumour Classification Books. He is also on the editorial board of a number of pathology and experimental research journals.

Research Impacts

The recognition that ADH is biologically very similar to DCIS has led to a policy of excising all ADH lesions diagnosed on core biopsies at breast screening assessment

The demonstration that LCIS is a clonal neoplastic proliferation with the same molecular phenotype as invasive lobular carcinoma, and the subsequent dissemination of this knowledge through publication (Lakhani SR 2003, Lancet) and conference presentations has also changed the management of LCIS. It is accepted that it is a non-obligate precursor, rather than a hyperplastic lesion.

The recognition of the pleomorphic variant of lobular is now changing the way this proliferation is managed. Like other lobular lesions, it is multifocal/bilateral but a more aggressive variant. There is considerable ongoing discussion on the international stage regarding management and my work has played a role in this policy change.

We have also shown that columnar cell lesions, which are increasingly being diagnosed in the screening program, are clonal lesions with a progressive relationship to low grade DCIS (Simpson PT et al 2005 Am J Surg Pathol). We have shown that morphological atypia is associated with molecular profiles similar to that of DCIS and hence patients with atypical lesions on core biopsy are now subjected to further excision. It has been shown subsequently that many of these patients have worse pathology on further resection.

My expertise, in diagnostic and molecular biology of pre-invasive breast disease has also been acknowledged in being appointed Head of Breast Screen Pathology, North Brisbane as well as being a member of the Breast Screen Quality (‘Q’) group in Queensland.

My work as part of the BCLC has demonstrated that BRCA1-related breast cancers are high grade, highly proliferative tumours and occurred in young women. Hence there was an immediate impact on breast screening protocols. I was invited to many meetings to discuss the pathology in relation to the following: (i) should mammography be used in young women and how effective would it be in dense breasts? (ii) should another modality such as MRI be considered? (iii) irrespective of the modality, should the screening interval be shortened to reduce the risk that patients would present with interval cancers?

All these issues have been addressed subsequent to the publications – in particular, I was member of the steering group that published the experience of using MRI in young women at high risk of breast cancer (Leach et al 2005 MARIBS The Lancet). MRI is now used in many countries to screen high-risk women. The screening interval has been reduced to 1 year as many patients did present with interval cancers as predicted by the pathology.

In extending the original work on morphology, my group has also demonstrated that a large proportion of BRCA1associated cancers are ER negative and ‘basal-like’. This led us to propose that this phenotype could be used to improve the risk estimation and carrier probability of women seen in family cancer clinics (Lakhani et al 2005 Clin Can Res).

We have now published a number of papers supporting the use of pathology data to improve risk estimation as well as improving the likelihood of unclassified variants (UVs) being pathogenic. This work has been done with previous BCLC collaborators (Prof Doug Easton) as well as with Georgia Chenevix-Trench and Amanda Spurdle at QIMR (Chenevix-Trench et al 2006 Can Res, Lovelock et al 2007 Br Can Res, Spurdle et al 2008 JCO, Spurdle et al 2009 Hum Mut, Mavaddat et al 2010 Br Can Res) This approach is now being incorporated into the genetics clinics.

Qualifications

  • Royal College of Pathologists, Royal College of Pathologists
  • Doctoral Diploma of Medicine, University College London
  • Bachelor of Medicine and Surgery and Medical Science, University College London
  • Bachelor (Honours), University College London

Publications

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Grants

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Supervision

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Publications

Book

Book Chapter

  • Future role of molecular profiling in small breast samples and personalised medicine

    Foong, Samuel Y. F., Simpson, Peter T., Cummings, Margaret C. and Lakhani, Sunil R. (2022). Future role of molecular profiling in small breast samples and personalised medicine. A comprehensive guide to core needle biopsies of the breast. (pp. 895-915) edited by Sandra J. Shin, Yunn-Yi Chen and Paula S. Ginter. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-031-05532-4_23

  • Columnar cell lesions

    Cummings, Margaret C., Simpson, Peter T. and Lakhani, Sunil R. (2020). Columnar cell lesions. Breast Pathology. Encyclopedia of Pathology. (pp. 71-79) edited by Anna Sapino and Janina Kulka. Cham, Switzerland: Springer. doi: 10.1007/978-3-319-62539-3

  • Breast cancer heterogeneity in primary and metastatic disease

    Kalinowski, Lauren, Saunus, Jodi M., McCart Reed, Amy E. and Lakhani, Sunil R. (2019). Breast cancer heterogeneity in primary and metastatic disease. Breast cancer metastasis and drug resistance: challenges and progress. (pp. 75-104) edited by Aamir Ahmad. Cham, Switzerland: Springer. doi: 10.1007/978-3-030-20301-6_6

  • Breast cancer - pathology and genetics

    McCart Reed, Amy Ellen, Kalaw, Emarene, Reid, Andrew Scott and Lakhani, Sunil R. (2018). Breast cancer - pathology and genetics. Encyclopedia of cancer. (pp. 170-183) edited by Paolo Boffetta and Pierre Hainaut. Cambridge, MA United States: Academic Press. doi: 10.1016/B978-0-12-801238-3.65263-7

  • Forgotten resources - the autopsy

    Smith, Deborah, Reed, Amy McCart and Lakhani, Sunil R. (2016). Forgotten resources - the autopsy. Molecular pathology in cancer research. (pp. 335-348) edited by Sunil R. Lakhani and Stephen B. Fox. New York, NY, U.S.A.: Springer . doi: 10.1007/978-1-4939-6643-1_15

  • Future role of molecular profiling in small breast samples and personalized medicine

    Sim, Sarah Yen Mi, Simpson, Peter T., Cummings, Margaret C. and Lakhani, Sunil R. (2016). Future role of molecular profiling in small breast samples and personalized medicine. A comprehensive guide to core needle biopsies of the breast. (pp. 803-817) edited by Sandra J. Shin. Cham, Switzerland: Springer. doi: 10.1007/978-3-319-26291-8

  • Introduction: Setting the scene, morphology to molecular

    Fox, Stephen B. and Lakhani, Sunil R. (2016). Introduction: Setting the scene, morphology to molecular. Molecular pathology in cancer research. (pp. v-vi) edited by Sunil R. Lakhani and Stephen B. Fox. New York, United States: Springer.

  • Breast Cancer

    Schnitt, Stuart J. and Lakhani, Sunil S. (2014). Breast Cancer. World Cancer Report. (pp. 362-373) edited by Bernard W. Stewart and Christopher P. Wild. Lyon, France: IARC.

  • Breast cancer heterogeneity in primary and metastatic disease

    Saunus, Jodi M., McCart-Reed, Amy, Momeny, Majid, Cummings, Margaret and Lakhani, Sunil R. (2013). Breast cancer heterogeneity in primary and metastatic disease. Breast Cancer Metastasis and Drug Resistance: Challenges and Progress. (pp. 65-95) edited by Aamir Ahmad. New York, NY, USA: Springer. doi: 10.1007/978-1-4614-5647-6

  • Flat epithelial atypia

    Schnitt, S., Collins, L., Lakhani, S. R. and Simpson, P. T. (2012). Flat epithelial atypia. WHO Classification of Tumours of the Breast. (pp. 87-87) Lyon, France: IARC Press.

  • Invasive lobular carcinoma

    Lakhani, S. R., Rakha, E. and Simpson, P. T. (2012). Invasive lobular carcinoma. WHO classification of tumours of the breast. (pp. 40-42) Lyon, France: IARC Press.

  • Lobular neoplasia

    Lakhani, S. R., Schnitt, S., O’Malley, F., van de Vijver, M., Simpson, P. T. and Palacios, J. (2012). Lobular neoplasia. WHO classification of tumours of the breast. (pp. 77-80) Lyon, France: IARC Press.

  • Molecular genetics of ductal carcinoma in situ and lobular carcinoma in situ

    Reis-Filho, Jorge S. and Lakhani, Sunil R. (2011). Molecular genetics of ductal carcinoma in situ and lobular carcinoma in situ. Breast pathology. (pp. 211-215) Philadelphia, PA, United States: Elsevier. doi: 10.1016/B978-1-4377-1757-0.00016-0

  • Genetic alterations in normal and malignant breast tissue

    Smart, Chanel, Simpson, Peter T., Vargas, Ana Cristina and Lakhani, Sunil R. (2011). Genetic alterations in normal and malignant breast tissue. Breast cancer, a lobar disease. (pp. 53-66) edited by Tot, Tibor. London, United Kingdom: Springer. doi: 10.1007/978-1-84996-314-5_4

  • High-risk lesions: ALH/LCIS/ADH

    Smart, Chanel E., Furnival, Colin M. and Lakhani, Sunil R. (2010). High-risk lesions: ALH/LCIS/ADH. Kuerer's breast surgical oncology. (pp. 179-187) edited by Henry Mark Kuerer. New York, U.S.A.: McGraw-Hill Medical.

  • Lobular carcinoma in situ

    Da Silva, Leonard, Simpson, Peter T. and Lakhani, Sunil R. (2010). Lobular carcinoma in situ. Management of breast diseases. (pp. 181-199) edited by Ismail Jatoi and M. Kaufmann. Heidelberg: Springer. doi: 10.1007/978-3-540-69743-5_11

  • Lobular carcinoma in situ : Biology and pathology

    Simpson, Peter T., Reis-Filho, Jorge S. and Lakhani, Sunil R. (2010). Lobular carcinoma in situ : Biology and pathology. Diseases of the breast. (pp. 333-340) edited by Jay R. Harris, Marc E. Lippman, C. Kent Osborne and Monica Morrow. Philadelphia: Lippencott, Williams & Wilkins.

  • Pathology of ovarian tumors in mutation carriers

    Penault-Llorca, Frédérique and Lakhani, Sunil R. (2007). Pathology of ovarian tumors in mutation carriers. Hereditary breast cancer. (pp. 333-344) edited by Claudine Isaacs and Timothy R. Rebbeck. Boca Raton, FL, United States: CRC Press. doi: 10.3109/9781420020366-23

  • Expression profiling using cDNA microarrays

    Jones, Chris, Simpson, Peter, Mackay, Alan and Lakhani, Sunil R. (2006). Expression profiling using cDNA microarrays. Breast cancer research protocols. (pp. 403-414) edited by Susan A. Brooks and Adrian Harris. Totowa, NJ, U.S.A.: Humana Press. doi: 10.1385/1-59259-969-9:403

  • Gene expression analysis using filter cDNA microarrays

    Simpson, Peter, Jones, Chris, Mackay, Alan and Lakhani, Sunil R. (2006). Gene expression analysis using filter cDNA microarrays. Breast cancer research protocols. (pp. 415-424) edited by Susan A. Brooks and Adrian Harris. Totowa, USA: Humana Press.

  • Molecular genetics of ADH/DCIS and ALH/LCIS

    Reis-Filho, J.S. and Lakhani, S.R. (2006). Molecular genetics of ADH/DCIS and ALH/LCIS. Breast Pathology. (pp. 185-189) edited by Goldblum, J.R.. Philadelphia, U.S.A.: Churchill Livingstone. doi: 10.1016/B978-0-443-06680-1.50023-5

  • Molecular investigation of breast disease

    Jones, Chris and Lakhani , Sunil R. (2006). Molecular investigation of breast disease. Early breast cancer: From screening to multidisciplinary management. (pp. 319-327) edited by G. Querci della Rovere, R. Warren and John R. Benson. London, U.K. ; New York, U.S.A.: Informa Healthcare.

  • Lobular carcinoma in situ: Biology and pathology

    Fulford, Laura G., Reis-Filho, Jorge S. and Lakhani, Sunni R. (2004). Lobular carcinoma in situ: Biology and pathology. Diseases of the breast. (pp. 489-495) edited by Jay R. Harris, Marc E. Lippman, Monica Morrow and C. Kent Osborne. Philadelphia, U.S.A.: Lippincott Williams & Wilkins.

  • Wound healing

    Lakhani, Sunil and Dogan, A. (2004). Wound healing. Clinical surgery in general : RCS course manual. (pp. 322-330) edited by Kirk, R.M. and Ribbans, W. J.. Edinburgh, United Kingdom: Churchill Livingstone.

  • Clinical case material

    Keshtgar, Mohammad R. S., Waddington, Wendy A., Lakhani, Sunil R. and Ell, Peter J. (1999). Clinical case material. The sentinel node in surgical oncology. (pp. 119-169) Berlin, Heidelberg: Springer Berlin Heidelberg. doi: 10.1007/978-3-642-60038-8_11

  • Surgical techniques

    Keshtgar, Mohammad R. S., Waddington, Wendy A., Lakhani, Sunil R. and Ell, Peter J. (1999). Surgical techniques. The sentinel node in surgical oncology. (pp. 79-89) Berlin, Heidelberg: Springer Berlin Heidelberg. doi: 10.1007/978-3-642-60038-8_7

Journal Article

  • B7-H3 expression in breast cancer and brain metastasis

    Joshi, Vaibhavi, Beecher, Kate, Lim, Malcolm, Stacey, Andrew, Feng, Yufan, Jat, Parmjit S., Duijf, Pascal H. G., Simpson, Peter T., Lakhani, Sunil R. and McCart Reed, Amy E. (2024). B7-H3 expression in breast cancer and brain metastasis. International Journal of Molecular Sciences, 25 (7) 3976, 1-17. doi: 10.3390/ijms25073976

  • Evaluating the accuracy of 18F-FDG PET-MRI scan in detecting regional lymph node disease in high risk breast cancer patients: PETAL study

    Murugappan, K., Lakhani, S., Ung, O., Kenny, L., Thomas, P., Rezai, S., Niland, C., McMahon, K. and Tran, S. (2024). Evaluating the accuracy of 18F-FDG PET-MRI scan in detecting regional lymph node disease in high risk breast cancer patients: PETAL study. The Breast, 74 103631, 103631. doi: 10.1016/j.breast.2023.103631

  • Evaluation of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA) Samples from Advanced Non-Small Cell Lung Cancer for Whole Genome, Whole Exome and Comprehensive Panel Sequencing

    Fielding, David, Lakis, Vanessa, Dalley, Andrew J., Chittoory, Haarika, Newell, Felicity, Koufariotis, Lambros T., Patch, Ann-Marie, Kazakoff, Stephen, Bashirzadeh, Farzad, Son, Jung Hwa, Ryan, Kimberley, Steinfort, Daniel, Williamson, Jonathan P., Bint, Michael, Pahoff, Carl, Nguyen, Phan Tien, Twaddell, Scott, Arnold, David, Grainge, Christopher, Pattison, Andrew, Fairbairn, David, Gune, Shailendra, Christie, Jemma, Holmes, Oliver, Leonard, Conrad, Wood, Scott, Pearson, John V., Lakhani, Sunil R., Waddell, Nicola ... Nones, Katia (2024). Evaluation of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA) Samples from Advanced Non-Small Cell Lung Cancer for Whole Genome, Whole Exome and Comprehensive Panel Sequencing. Cancers, 16 (4), 785. doi: 10.3390/cancers16040785

  • <scp>NDRG1</scp> is a prognostic biomarker in breast cancer and breast cancer brain metastasis

    Joshi, Vaibhavi, Stacey, Andrew, Feng, Yufan, Kalita‐de Croft, Priyakshi, Duijf, Pascal HG, Simpson, Peter T, Lakhani, Sunil R and McCart Reed, Amy E (2024). NDRG1 is a prognostic biomarker in breast cancer and breast cancer brain metastasis. The Journal of Pathology: Clinical Research, 10 (2) e12364. doi: 10.1002/2056-4538.12364

  • Detailed DNA methylation characterisation of phyllodes tumours identifies a signature of malignancy and distinguishes phyllodes from metaplastic breast carcinoma

    Meyer, Braydon, Stirzaker, Clare, Ramkomuth, Sonny, Harvey, Kate, Chan, Belinda, Lee, Cheok Soon, Karim, Rooshdiya, Deng, Niantao, Avery-Kiejda, Kelly A., Scott, Rodney J., Lakhani, Sunil, Fox, Stephen, Robbins, Elizabeth, Shin, Joo-Shik, Beith, Jane, Gill, Anthony, Sioson, Loretta, Chan, Charles, Krishnaswamy, Mrudula, Cooper, Caroline, Warrier, Sanjay, Mak, Cindy, Rasko, John E.J., Bailey, Charles G., Swarbrick, Alexander, Clark, Susan J., O'Toole, Sandra and Pidsley, Ruth (2024). Detailed DNA methylation characterisation of phyllodes tumours identifies a signature of malignancy and distinguishes phyllodes from metaplastic breast carcinoma. Journal of Pathology, 262 (4), 1-15. doi: 10.1002/path.6250

  • A dedicated structured data set for reporting of invasive carcinoma of the breast in the setting of neoadjuvant therapy: recommendations from the International Collaboration on Cancer Reporting (ICCR)

    Bossuyt, Veerle, Provenzano, Elena, Symmans, W Fraser, Webster, Fleur, Allison, Kimberly H, Dang, Chau, Helenice, Gobbi, Kulka, Janina, Lakhani, Sunil R, Moriya, Takuya, Quinn, Cecily M, Sapino, Anna, Schnitt, Stuart, Sibbering, D Mark, Slodkowska, Elzbieta, Yang, Wentao, Tan, Puay Hoon and Ellis, Ian (2024). A dedicated structured data set for reporting of invasive carcinoma of the breast in the setting of neoadjuvant therapy: recommendations from the International Collaboration on Cancer Reporting (ICCR). Histopathology. doi: 10.1111/his.15165

  • Differential response of placental cells to high D‐glucose and its impact on extracellular vesicle biogenesis and trafficking via small GTPase Ras‐related protein RAB‐7A

    Palma, Carlos, Lai, Andrew, Scholz‐Romero, Katherin, Chittoory, Haarika, Van Haeringen, Benjamin, Carrion, Flavio, Handberg, Aase, Lappas, Martha, Lakhani, Sunil R., McCart Reed, Amy E, McIntyre, H. David, Nair, Soumyalekshmi and Salomon, Carlos (2024). Differential response of placental cells to high D‐glucose and its impact on extracellular vesicle biogenesis and trafficking via small GTPase Ras‐related protein RAB‐7A. Journal of Extracellular Biology, 3 (1) e135. doi: 10.1002/jex2.135

  • Robust mapping of spatiotemporal trajectories and cell–cell interactions in healthy and diseased tissues

    Pham, Duy, Tan, Xiao, Balderson, Brad, Xu, Jun, Grice, Laura F., Yoon, Sohye, Willis, Emily F., Tran, Minh, Lam, Pui Yeng, Raghubar, Arti, Kalita-de Croft, Priyakshi, Lakhani, Sunil, Vukovic, Jana, Ruitenberg, Marc J. and Nguyen, Quan H. (2023). Robust mapping of spatiotemporal trajectories and cell–cell interactions in healthy and diseased tissues. Nature Communications, 14 (1) 7739, 1-25. doi: 10.1038/s41467-023-43120-6

  • Targeted hyperbranched nanoparticles for delivery of doxorubicin in breast cancer brain metastasis

    Lim, Malcolm, Fletcher, Nicholas L., Saunus, Jodi M., McCart Reed, Amy E., Chittoory, Haarika, Simpson, Peter T., Thurecht, Kristofer J. and Lakhani, Sunil R. (2023). Targeted hyperbranched nanoparticles for delivery of doxorubicin in breast cancer brain metastasis. Molecular Pharmaceutics, 20 (12), 6169-6183. doi: 10.1021/acs.molpharmaceut.3c00558

  • Branchioma: immunohistochemical and molecular genetic study of 23 cases highlighting frequent loss of retinoblastoma 1 immunoexpression

    Bradová, Martina, Thompson, Lester D. R., Hyrcza, Martin, Vaněček, Tomáš, Grossman, Petr, Michal, Michael, Hájková, Veronika, Taheri, Touraj, Rupp, Niels, Suster, David, Lakhani, Sunil, Nikolov, Dimitar Hadži, Žalud, Radim, Skálová, Alena, Michal, Michal and Agaimy, Abbas (2023). Branchioma: immunohistochemical and molecular genetic study of 23 cases highlighting frequent loss of retinoblastoma 1 immunoexpression. Virchows Archiv, 484 (1), 1-15. doi: 10.1007/s00428-023-03697-1

  • Discrepancies in tumor mutation burden reporting from sequential endobronchial ultrasound transbronchial needle aspiration samples within single lymph node stations - brief report

    Fielding, David, Dalley, Andrew J., Singh, Mahendra, Nandakumar, Lakshmy, Lakis, Vanessa, Chittoory, Haarika, Fairbairn, David, Patch, Ann-Marie, Kazakoff, Stephen H., Ferguson, Kaltin, Bashirzadeh, Farzad, Bint, Michael, Pahoff, Carl, Son, Jung Hwa, Ryan, Kimberley, Hodgson, Alan, Sharma, Sowmya, Pearson, John V., Waddell, Nicola, Lakhani, Sunil R., Hartel, Gunter, Simpson, Peter T. and Nones, Katia (2023). Discrepancies in tumor mutation burden reporting from sequential endobronchial ultrasound transbronchial needle aspiration samples within single lymph node stations - brief report. Frontiers in Oncology, 13 ARTN 1259882, 1-10. doi: 10.3389/fonc.2023.1259882

  • Improved concordance of challenging human epidermal growth factor receptor 2 dual in-situ hybridisation cases with the use of a digital image analysis algorithm in breast cancer

    Gough, Madeline, Liu, Cheng, Srinivasan, Bhuvana, Wilkinson, Lisa, Dunk, Louisa, Yang, Yuanhao, Schreiber, Veronika, Tuffaha, Haitham, Kryza, Thomas, Hooper, John D., Lakhani, Sunil R. and Snell, Cameron E. (2023). Improved concordance of challenging human epidermal growth factor receptor 2 dual in-situ hybridisation cases with the use of a digital image analysis algorithm in breast cancer. Histopathology, 83 (4), 647-656. doi: 10.1111/his.15000

  • Predicting breast cancer-specific survival in metaplastic breast cancer patients using machine learning algorithms

    Feng, Yufan, McGuire, Natasha, Walton, Alexandra, Fox, Stephen, Papa, Antonella, Lakhani, Sunil R. and McCart Reed, Amy E. (2023). Predicting breast cancer-specific survival in metaplastic breast cancer patients using machine learning algorithms. Journal of Pathology Informatics, 14 100329, 100329. doi: 10.1016/j.jpi.2023.100329

  • Obesity-associated changes in molecular biology of primary breast cancer

    Nguyen, Ha-Linh, Geukens, Tatjana, Maetens, Marion, Aparicio, Samuel, Bassez, Ayse, Borg, Ake, Brock, Jane, Broeks, Annegien, Caldas, Carlos, Cardoso, Fatima, De Schepper, Maxim, Delorenzi, Mauro, Drukker, Caroline A., Glas, Annuska M., Green, Andrew R., Isnaldi, Edoardo, Eyfjörð, Jórunn, Khout, Hazem, Knappskog, Stian, Krishnamurthy, Savitri, Lakhani, Sunil R., Langerod, Anita, Martens, John W. M., McCart Reed, Amy E., Murphy, Leigh, Naulaerts, Stefan, Nik-Zainal, Serena, Nevelsteen, Ines, Neven, Patrick ... Desmedt, Christine (2023). Obesity-associated changes in molecular biology of primary breast cancer. Nature Communications, 14 (1) 4418. doi: 10.1038/s41467-023-39996-z

  • Obesity-associated changes in molecular biology of primary breast cancer

    Nguyen, Ha-Linh, Geukens, Tatjana, Maetens, Marion, Aparicio, Samuel, Bassez, Ayse, Borg, Ake, Brock, Jane, Broeks, Annegien, Caldas, Carlos, Cardoso, Fatima, De Schepper, Maxim, Delorenzi, Mauro, Drukker, Caroline A., Glas, Annuska M., Green, Andrew R., Isnaldi, Edoardo, Eyfjoro, Jorunn, Khout, Hazem, Knappskog, Stian, Krishnamurthy, Savitri, Lakhani, Sunil R., Langerod, Anita, Martens, John W. M., Reed, Amy E. McCart, Murphy, Leigh, Naulaerts, Stefan, Nik-Zainal, Serena, Nevelsteen, Ines, Neven, Patrick ... Desmedt, Christine (2023). Obesity-associated changes in molecular biology of primary breast cancer. Nature Communications, 14 (1) ARTN 4418. doi: 10.1038/s41467-023-39996-z

  • Redefining normal breast cell populations using long noncoding RNAs

    Bitar, Mainá, Rivera, Isela Sarahi, Almeida, Isabela, Shi, Wei, Ferguson, Kaltin, Beesley, Jonathan, Lakhani, Sunil R., Edwards, Stacey L. and French, Juliet D. (2023). Redefining normal breast cell populations using long noncoding RNAs. Nucleic Acids Research, 51 (12), 6389-6410. doi: 10.1093/nar/gkad339

  • Whole genome sequencing in advanced lung cancer can be performed using diff-quik cytology smears derived from endobronchial ultrasound, transbronchial needle aspiration (EBUS TBNA)

    Fielding, David, Dalley, Andrew J., Singh, Mahendra, Nandakumar, Lakshmy, Lakis, Vanessa, Chittoory, Haarika, Fairbairn, David, Ferguson, Kaltin, Bashirzadeh, Farzad, Bint, Michael, Pahoff, Carl, Son, Jung Hwa, Hodgson, Alan, Pearson, John V., Waddell, Nicola, Lakhani, Sunil R., Hartel, Gunter, Nones, Katia and Simpson, Peter T. (2023). Whole genome sequencing in advanced lung cancer can be performed using diff-quik cytology smears derived from endobronchial ultrasound, transbronchial needle aspiration (EBUS TBNA). Lung, 201 (4), 407-413. doi: 10.1007/s00408-023-00631-9

  • BRCA1 and BRCA2 carriers with breast, ovarian and prostate cancer demonstrate a different pattern of metastatic disease compared with non-carriers: results from a rapid autopsy programme

    Thorne, Heather, Devereux, Lisa, Li, Jason, Alsop, Kathryn, Christie, Liz, van Geelen, Courtney T., Burdett, Nikki, Pishas, Kathleen I, Woodford, Noel, Leditschke, Jodie, Izzath, Mohamed H. M. A., Strachan, Kate, Young, Gregory, Jaravaza, Rufaro D., Madadin, Mohammed S., Archer, Melanie, Glengarry, Joanna, Iles, Linda, Rathnaweera, Ajith, Hampson, Clare, Almazrooei, Khamis, Burke, Michael, Bandara, Pradeep, Ranson, David, Saeedi, Essa, McNally, Orla, Mileshkin, Linda, Hamilton, Anne, Ananda, Sumitra ... Fox, Stephen (2023). BRCA1 and BRCA2 carriers with breast, ovarian and prostate cancer demonstrate a different pattern of metastatic disease compared with non-carriers: results from a rapid autopsy programme. Histopathology, 83 (1), 91-103. doi: 10.1111/his.14906

  • Evaluating Diff‐Quik cytology smears for large‐panel mutation testing in lung cancer—Predicting DNA content and success with low‐malignant‐cellularity samples

    Fielding, David I., Dalley, Andrew J., Singh, Mahendra, Nandakumar, Lakshmy, Lakis, Vanessa, Chittoory, Haarika, Fairbairn, David, Patch, Ann‐Marie, Kazakoff, Stephen H., Ferguson, Kaltin, Bashirzadeh, Farzad, Bint, Michael, Pahoff, Carl, Son, Jung Hwa, Hodgson, Alan, Sharma, Sowmya, Waddell, Nicola, Lakhani, Sunil R., Hartel, Gunter, Nones, Katia and Simpson, Peter T. (2023). Evaluating Diff‐Quik cytology smears for large‐panel mutation testing in lung cancer—Predicting DNA content and success with low‐malignant‐cellularity samples. Cancer Cytopathology, 131 (6), 373-382. doi: 10.1002/cncy.22690

  • The Queensland IMplementation of PRecision Oncology in brEast cancer ( Q‐IMPROvE ) pilot study

    McCart Reed, Amy E., Hollway, Georgina, The Q‐IMPROvE study group and Lakhani, Sunil (2023). The Queensland IMplementation of PRecision Oncology in brEast cancer ( Q‐IMPROvE ) pilot study. Medical Journal of Australia, 218 (8), 374-375. doi: 10.5694/mja2.51900

  • COMMD3 loss drives invasive breast cancer growth by modulating copper homeostasis

    Hancock, Janelle L., Kalimutho, Murugan, Straube, Jasmin, Lim, Malcolm, Gresshoff, Irma, Saunus, Jodi M., Lee, Jason S., Lakhani, Sunil R., Simpson, Kaylene J., Bush, Ashley I., Anderson, Robin L. and Khanna, Kum Kum (2023). COMMD3 loss drives invasive breast cancer growth by modulating copper homeostasis. Journal of Experimental and Clinical Cancer Research, 42 (1) 90, 1-16. doi: 10.1186/s13046-023-02663-8

  • Phyllodes tumour evidence gaps mapped from the 5th edition of the WHO classification of tumours of the breast

    Md Nasir, Nur Diyana, Koh, Valerie Cui Yun, Cree, Ian A., Indave Ruiz, Blanca Iciar, Del Águila, Javier, Armon, Subasri, Fox, Stephen B., Lakhani, Sunil R. and Tan, Puay Hoon (2023). Phyllodes tumour evidence gaps mapped from the 5th edition of the WHO classification of tumours of the breast. Histopathology, 82 (5), 704-712. doi: 10.1111/his.14856

  • Hereditary breast cancer: syndromes, tumour pathology and molecular testing

    Sokolova, A, Johnstone, K J, McCart Reed, A E, Simpson, P T and Lakhani, S R (2023). Hereditary breast cancer: syndromes, tumour pathology and molecular testing. Histopathology, 82 (1), 70-82. doi: 10.1111/his.14808

  • Survey of recurrent diagnostic challenges in breast phyllodes tumours

    Tan, Benjamin Yongcheng, Fox, Stephen B., Lakhani, Sunil R. and Tan, Puay Hoon (2023). Survey of recurrent diagnostic challenges in breast phyllodes tumours. Histopathology, 82 (1), 95-105. doi: 10.1111/his.14730

  • Fetal akinesia deformation sequence syndrome associated with recessive <i>TTN</i> variants

    Alkhunaizi, Ebba, Martin, Nicole, Jelin, Angie C., Rosner, Mara, Bailey, Diana J., Steiner, Laurie A., Lakhani, Saquib, Ji, Weizhen, Katzman, Philip J., Forster, Katherine R., Jarinova, Olga, Shannon, Patrick and Chitayat, David (2022). Fetal akinesia deformation sequence syndrome associated with recessive TTN variants. American Journal of Medical Genetics Part a, 191 (3), 760-769. doi: 10.1002/ajmg.a.63071

  • Author Correction: Divergent mutational processes distinguish hypoxic and normoxic tumours (Nature Communications, (2020), 11, 1, (737), 10.1038/s41467-019-14052-x)

    Bhandari, Vinayak, Li, Constance H., Bristow, Robert G., Boutros, Paul C., Aaltonen, Lauri A., Abascal, Federico, Abeshouse, Adam, Aburatani, Hiroyuki, Adams, David J., Agrawal, Nishant, Ahn, Keun Soo, Ahn, Sung-Min, Aikata, Hiroshi, Akbani, Rehan, Akdemir, Kadir C., Al-Ahmadie, Hikmat, Al-Sedairy, Sultan T., Al-Shahrour, Fatima, Alawi, Malik, Albert, Monique, Aldape, Kenneth, Alexandrov, Ludmil B., Ally, Adrian, Alsop, Kathryn, Alvarez, Eva G., Amary, Fernanda, Amin, Samirkumar B., Aminou, Brice, Ammerpohl, Ole ... von Mering, Christian (2022). Author Correction: Divergent mutational processes distinguish hypoxic and normoxic tumours (Nature Communications, (2020), 11, 1, (737), 10.1038/s41467-019-14052-x). Nature Communications, 13 (1) 7569. doi: 10.1038/s41467-022-32339-4

  • Author Correction: Inferring structural variant cancer cell fraction (Nature Communications, (2020), 11, 1, (730), 10.1038/s41467-020-14351-8)

    Cmero, Marek, Yuan, Ke, Ong, Cheng Soon, Schröder, Jan, Adams, David J., Anur, Pavana, Beroukhim, Rameen, Boutros, Paul C., Bowtell, David D. L., Campbell, Peter J., Cao, Shaolong, Christie, Elizabeth L., Cun, Yupeng, Dawson, Kevin J., Demeulemeester, Jonas, Dentro, Stefan C., Deshwar, Amit G., Donmez, Nilgun, Drews, Ruben M., Eils, Roland, Fan, Yu, Fittall, Matthew W., Garsed, Dale W., Gerstung, Moritz, Getz, Gad, Gonzalez, Santiago, Ha, Gavin, Haase, Kerstin, Imielinski, Marcin ... von Mering, Christian (2022). Author Correction: Inferring structural variant cancer cell fraction (Nature Communications, (2020), 11, 1, (730), 10.1038/s41467-020-14351-8). Nature Communications, 13 (1) 7568. doi: 10.1038/s41467-022-32338-5

  • Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer

    Geyer, C. E., Garber, J. E., Gelber, R. D., Yothers, G., Taboada, M., Ross, L., Rastogi, P., Cui, K., Arahmani, A., Aktan, G., Armstrong, A. C., Arnedos, M., Balmaña, J., Bergh, J., Bliss, J., Delaloge, S., Domchek, S. M., Eisen, A., Elsafy, F., Fein, L. E., Fielding, A., Ford, J. M., Friedman, S., Gelmon, K. A., Gianni, L., Gnant, M., Hollingsworth, S. J., Im, S. A., Jager, A. ... Cho, Eun Kyung (2022). Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer. Annals of Oncology, 33 (12), 1250-1268. doi: 10.1016/j.annonc.2022.09.159

  • NDRG1 in Cancer: A Suppressor, Promoter, or Both?

    Joshi, Vaibhavi, Lakhani, Sunil R. and McCart Reed, Amy E. (2022). NDRG1 in Cancer: A Suppressor, Promoter, or Both?. Cancers, 14 (23) 5739, 1-15. doi: 10.3390/cancers14235739

  • Comprehensive histopathologic and genomic analysis of a novel case of lipoblastoma-like tumour of the vulva demonstrating malignant behaviour

    Kutasovic, Jamie R., Nones, Katia, Lakis, Vanessa, Koufariotis, Lambros T., Ferguson, Kaltin, McCart Reed, Amy E., Simpson, Peter T., Lakhani, Sunil R., Mar Fan, Helen, Higgins, Megan, Davies, Janene, Payton, Diane and Taege, Lucinda (2022). Comprehensive histopathologic and genomic analysis of a novel case of lipoblastoma-like tumour of the vulva demonstrating malignant behaviour. Human Pathology Reports, 30 300678, 300678. doi: 10.1016/j.hpr.2022.300678

  • Prospective optimization of endobronchial ultrasound-guided transbronchial needle aspiration lymph node assessment for lung cancer: Three needle agitations are noninferior to 10 agitations for adequate tumor cell and DNA yield

    Fielding, David, Dalley, Andrew J., Singh, Mahendra, Nandakumar, Lakshmy, Nones, Katia, Lakis, Vanessa, Chittoory, Haarika, Ferguson, Kaltin, Bashirzadeh, Farzad, Bint, Michael, Pahoff, Carl, Son, Jung Hwa, Hodgson, Alan, Sharma, Sowmya, Godbolt, David, Coleman, Kylie, Whitfield, Lenore, Waddell, Nicola, Lakhani, Sunil R., Hartel, Gunter and Simpson, Peter T. (2022). Prospective optimization of endobronchial ultrasound-guided transbronchial needle aspiration lymph node assessment for lung cancer: Three needle agitations are noninferior to 10 agitations for adequate tumor cell and DNA yield. JTO Clinical and Research Reports, 3 (10) 100403, 100403. doi: 10.1016/j.jtocrr.2022.100403

  • Modeling brain metastasis by internal carotid artery injection of cancer cells

    Lim, Malcolm, Fletcher, Nicholas, Reed, Amy Mccart, Flint, Melanie, Thurecht, Kristofer, Saunus, Jodi and Lakhani, Sunil R. (2022). Modeling brain metastasis by internal carotid artery injection of cancer cells. Journal of Visualized Experiments, 2022 (186) e64216. doi: 10.3791/64216

  • The increasing importance of pathology in modern clinical trial conduct: OlympiA as a case in point

    Kalinowski, Lauren, Viale, Giuseppe, Domchek, Susan, Tutt, Andrew, Lucas, Peter C. and Lakhani, Sunil R. (2022). The increasing importance of pathology in modern clinical trial conduct: OlympiA as a case in point. Pathology, 54 (5), 511-516. doi: 10.1016/j.pathol.2022.05.003

  • Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer

    Saunus, Jodi M., De Luca, Xavier M., Northwood, Korinne, Raghavendra, Ashwini, Hasson, Alexander, McCart Reed, Amy E., Lim, Malcolm, Lal, Samir, Vargas, A. Cristina, Kutasovic, Jamie R., Dalley, Andrew J., Miranda, Mariska, Kalaw, Emarene, Kalita-de Croft, Priyakshi, Gresshoff, Irma, Al-Ejeh, Fares, Gee, Julia M. W., Ormandy, Chris, Khanna, Kum Kum, Beesley, Jonathan, Chenevix-Trench, Georgia, Green, Andrew R., Rakha, Emad A., Ellis, Ian O., Nicolau, Dan V., Simpson, Peter T. and Lakhani, Sunil R. (2022). Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer. npj Breast Cancer, 8 (1) 57, 1-16. doi: 10.1038/s41523-022-00425-x

  • N-glycolylneuraminic acid serum biomarker levels are elevated in breast cancer patients at all stages of disease

    Shewell, Lucy K., Day, Christopher J., Kutasovic, Jamie R., Abrahams, Jodie L., Wang, Jing, Poole, Jessica, Niland, Colleen, Ferguson, Kaltin, Saunus, Jodi M., Lakhani, Sunil R., von Itzstein, Mark, Paton, James C., Paton, Adrienne W. and Jennings, Michael P. (2022). N-glycolylneuraminic acid serum biomarker levels are elevated in breast cancer patients at all stages of disease. BMC Cancer, 22 (1) 334, 334. doi: 10.1186/s12885-022-09428-0

  • Emerging biomarkers for diagnosis, prevention and treatment of brain metastases—from biology to clinical utility

    Kalita-de Croft, Priyakshi, Joshi, Vaibhavi, Saunus, Jodi M. and Lakhani, Sunil R. (2022). Emerging biomarkers for diagnosis, prevention and treatment of brain metastases—from biology to clinical utility. Diseases, 10 (1), 11. doi: 10.3390/diseases10010011

  • Landscape of epidermal growth factor receptor heterodimers in brain metastases

    Lim, Malcolm, Nguyen, Tam H., Niland, Colleen, Reid, Lynne E., Jat, Parmjit S., Saunus, Jodi M. and Lakhani, Sunil R. (2022). Landscape of epidermal growth factor receptor heterodimers in brain metastases. Cancers, 14 (3), 533. doi: 10.3390/cancers14030533

  • Whole genome deep sequencing analysis of cell-free DNA in samples with low tumour content

    Ganesamoorthy, Devika, Robertson, Alan James, Chen, Wenhan, Hall, Michael B., Cao, Minh Duc, Ferguson, Kaltin, Lakhani, Sunil R., Nones, Katia, Simpson, Peter T. and Coin, Lachlan J. M. (2022). Whole genome deep sequencing analysis of cell-free DNA in samples with low tumour content. BMC Cancer, 22 (1) 85, 85. doi: 10.1186/s12885-021-09160-1

  • Blood-derived extracellular vesicle-associated miR-3182 detects non-small cell lung cancer patients

    Visan, Kekoolani S., Lobb, Richard J., Wen, Shu Wen, Bedo, Justin, Lima, Luize G., Krumeich, Sophie, Palma, Carlos, Ferguson, Kaltin, Green, Ben, Niland, Colleen, Cloonan, Nicole, Simpson, Peter T., McCart Reed, Amy E., Everitt, Sarah J., MacManus, Michael P., Hartel, Gunter, Salomon, Carlos, Lakhani, Sunil R., Fielding, David and Möller, Andreas (2022). Blood-derived extracellular vesicle-associated miR-3182 detects non-small cell lung cancer patients. Cancers, 14 (1) 257, 257. doi: 10.3390/cancers14010257

  • The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group

    El Bairi, Khalid, Haynes, Harry R., Blackley, Elizabeth, Fineberg, Susan, Shear, Jeffrey, Turner, Sophia, de Freitas, Juliana Ribeiro, Sur, Daniel, Amendola, Luis Claudio, Gharib, Masoumeh, Kallala, Amine, Arun, Indu, Azmoudeh-Ardalan, Farid, Fujimoto, Luciana, Sua, Luz F., Liu, Shi-Wei, Lien, Huang-Chun, Kirtani, Pawan, Balancin, Marcelo, El Attar, Hicham, Guleria, Prerna, Yang, Wenxian, Shash, Emad, Chen, I-Chun, Bautista, Veronica, Do Prado Moura, Jose Fernando, Rapoport, Bernardo L., Castaneda, Carlos, Spengler, Eunice ... The International Immuno-Oncology Biomarker Working Group (2021). The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group. npj Breast Cancer, 7 (1) 150. doi: 10.1038/s41523-021-00346-1

  • The mutational landscape of melanoma brain metastases presenting as the first visceral site of recurrence

    Rabbie, Roy, Ferguson, Peter, Wong, Kim, Couturier, Dominique-Laurent, Moran, Una, Turner, Clinton, Emanuel, Patrick, Haas, Kerstin, Saunus, Jodi M., Davidson, Morgan R., Lakhani, Sunil R., Shivalingam, Brindha, Long, Georgina, Parkinson, Christine, Osman, Iman, Scolyer, Richard A., Corrie, Pippa and Adams, David J. (2021). The mutational landscape of melanoma brain metastases presenting as the first visceral site of recurrence. British Journal of Cancer, 124 (1), 156-160. doi: 10.1038/s41416-020-01090-2

  • Elevating CDCA3 levels enhances tyrosine kinase inhibitor sensitivity in TKI-resistant EGFR mutant non-small-cell lung cancer

    Sahin, Katherine B., Shah, Esha T., Ferguson, Genevieve P., Molloy, Christopher, Kalita-de Croft, Priyakshi, Hayes, Sarah A., Hudson, Amanda, Colvin, Emily, Kamitakahara, Hannah, Harvie, Rozelle, Hasovits, Csilla, Khan, Tashbib, Duijf, Pascal H. G., Howell, Viive M., He, Yaowu, Bolderson, Emma, Hooper, John D., Lakhani, Sunil R., Richard, Derek J., O’Byrne, Kenneth J. and Adams, Mark N. (2021). Elevating CDCA3 levels enhances tyrosine kinase inhibitor sensitivity in TKI-resistant EGFR mutant non-small-cell lung cancer. Cancers, 13 (18) 4651, 4651. doi: 10.3390/cancers13184651

  • Correction: McCart Reed et al. The Genomic Landscape of Lobular Breast Cancer. Cancers 2021, 13, 1950

    McCart Reed, Amy E., Foong, Samuel, Kutasovic, Jamie R., Nones, Katia, Waddell, Nicola, Lakhani, Sunil R. and Simpson, Peter T. (2021). Correction: McCart Reed et al. The Genomic Landscape of Lobular Breast Cancer. Cancers 2021, 13, 1950. Cancers, 13 (16) 4010. doi: 10.3390/cancers13164010

  • SP142 PD-L1 scoring shows high interobserver and intraobserver agreement in triple-negative breast carcinoma but overall low percentage agreement with other PD-L1 clones SP263 and 22C3

    Pang, Jia-Min B., Castles, Belinda, Byrne, David J., Button, Peter, Hendry, Shona, Lakhani, Sunil R., Sivasubramaniam, Vanathi, Cooper, Wendy A., Armes, Jane, Millar, Ewan K.A., Raymond, Wendy, Roberts-Thomson, Samuel, Kumar, Beena, Burr, Marian, Selinger, Christina, Harvey, Kate, Chan, Charles, Beith, Jane, Clouston, David, O'Toole, Sandra A. and Fox, Stephen B. (2021). SP142 PD-L1 scoring shows high interobserver and intraobserver agreement in triple-negative breast carcinoma but overall low percentage agreement with other PD-L1 clones SP263 and 22C3. American Journal of Surgical Pathology, 45 (8), 1108-1117. doi: 10.1097/PAS.0000000000001701

  • Adjuvant olaparib for patients with BRCA1- or BRCA2-mutated breast cancer

    Tutt, Andrew N. J., Garber, Judy E., Kaufman, Bella, Viale, Giuseppe, Fumagalli, Debora, Rastogi, Priya, Gelber, Richard D., de Azambuja, Evandro, Fielding, Anitra, Balmaña, Judith, Domchek, Susan M., Gelmon, Karen A., Hollingsworth, Simon J., Korde, Larissa A., Linderholm, Barbro, Bandos, Hanna, Senkus, Elżbieta, Suga, Jennifer M., Shao, Zhimin, Pippas, Andrew W., Nowecki, Zbigniew, Huzarski, Tomasz, Ganz, Patricia A., Lucas, Peter C., Baker, Nigel, Loibl, Sibylle, McConnell, Robin, Piccart, Martine, Schmutzler, Rita ... Geyer, Charles E. (2021). Adjuvant olaparib for patients with BRCA1- or BRCA2-mutated breast cancer. New England Journal of Medicine, 384 (25), 2394-2405. doi: 10.1056/NEJMoa2105215

  • Altered calcium influx pathways in cancer-associated fibroblasts

    Sadras, Francisco, Stewart, Teneale A., Robitaille, Mélanie, Peters, Amelia A., Croft, Priyakshi Kalita-de, Soon, Patsy S., Saunus, Jodi M., Lakhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2021). Altered calcium influx pathways in cancer-associated fibroblasts. Biomedicines, 9 (6) 680, 1-13. doi: 10.3390/biomedicines9060680

  • Characterization of immune cell subsets of tumor infiltrating lymphocytes in brain metastases

    Croft, Priyakshi Kalita-de, Chittoory, Haarika, Nguyen, Tam H., Saunus, Jodi M., Kim, Woo Gyeong, Reed, Amy E. McCart, Lim, Malcolm, De Luca, Xavier M., Ferguson, Kaltin, Niland, Colleen, Mazzieri, Roberta, Dolcetti, Riccardo, Simpson, Peter T. and Lakhani, Sunil R. (2021). Characterization of immune cell subsets of tumor infiltrating lymphocytes in brain metastases. Biology, 10 (5) 425, 425. doi: 10.3390/biology10050425

  • The genomic landscape of lobular breast cancer

    McCart Reed, Amy E., Foong, Samuel, Kutasovic, Jamie R., Nones, Katia, Waddell, Nicola, Lakhani, Sunil R. and Simpson, Peter T. (2021). The genomic landscape of lobular breast cancer. Cancers, 13 (8) 1950. doi: 10.3390/cancers13081950

  • Tumor signature analysis implicates hereditary cancer genes in endometrial cancer development

    Kondrashova, Olga, Shamsani, Jannah, O’Mara, Tracy A., Newell, Felicity, Reed, Amy E. McCart, Lakhani, Sunil R., Kirk, Judy, Pearson, John V., Waddell, Nicola and Spurdle, Amanda B. (2021). Tumor signature analysis implicates hereditary cancer genes in endometrial cancer development. Cancers, 13 (8) 1762, 1-16. doi: 10.3390/cancers13081762

  • Metaplastic carcinomas of the breast without evidence of epithelial differentiation: a diagnostic approach for management

    Rakha, Emad A., Quinn, Cecily M., Foschini, Maria Pia, Munoz Martin, Monica, Dabbs, David J., Lakhani, Sunil, Varga, Zsuzsanna, Pinder, Sarah E., Schmitt, Fernando C., Reis-Filho, Jorge S., Fox, Stephen B., Ellis, Ian O., Tan, Puay-Hoon and Mihai, Raluca (2021). Metaplastic carcinomas of the breast without evidence of epithelial differentiation: a diagnostic approach for management. Histopathology, 78 (5), 759-771. doi: 10.1111/his.14290

  • Spatial profiling technologies and applications for brain cancers

    Kalita-de Croft, Priyakshi, Rad, Habib Sadeghi, Gasper, Harry, O'Byrne, Ken, Lakhani, Sunil R. and Kulasinghe, Arutha (2021). Spatial profiling technologies and applications for brain cancers. Expert Review of Molecular Diagnostics, 21 (3), 323-332. doi: 10.1080/14737159.2021.1900735

  • CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers

    Johnson, Nichola, Maguire, Sarah, Morra, Anna, Kapoor, Pooja Middha, Tomczyk, Katarzyna, Jones, Michael E., Schoemaker, Minouk J., Gilham, Clare, Bolla, Manjeet K., Wang, Qin, Dennis, Joe, Ahearn, Thomas U., Andrulis, Irene L., Anton-Culver, Hoda, Antonenkova, Natalia N., Arndt, Volker, Aronson, Kristan J., Augustinsson, Annelie, Baynes, Caroline, Freeman, Laura E. Beane, Beckmann, Matthias W., Benitez, Javier, Bermisheva, Marina, Blomqvist, Carl, Boeckx, Bram, Bogdanova, Natalia V., Bojesen, Stig E., Brauch, Hiltrud, Brenner, Hermann ... Fletcher, Olivia (2021). CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers. British Journal of Cancer, 124 (4), 842-854. doi: 10.1038/s41416-020-01185-w

  • An update on the molecular pathology of metaplastic breast cancer

    McCart Reed, Amy E., Kalaw, Emarene M. and Lakhani, Sunil R. (2021). An update on the molecular pathology of metaplastic breast cancer. Breast Cancer, 13, 161-170. doi: 10.2147/bctt.s296784

  • Invasive lobular carcinoma of the breast: the increasing importance of this special subtype

    McCart Reed, Amy E., Kalinowski, Lauren, Simpson, Peter T. and Lakhani, Sunil R. (2021). Invasive lobular carcinoma of the breast: the increasing importance of this special subtype. Breast Cancer Research, 23 (1) 6, 6. doi: 10.1186/s13058-020-01384-6

  • Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials

    Hudeček, Jan, Voorwerk, Leonie, van Seijen, Maartje, Nederlof, Iris, de Maaker, Michiel, van den Berg, Jose, van de Vijver, Koen K., Sikorska, Karolina, Adams, Sylvia, Demaria, Sandra, Viale, Giuseppe, Nielsen, Torsten O., Badve, Sunil S., Michiels, Stefan, Symmans, William Fraser, Sotiriou, Christos, Rimm, David L., Hewitt, Stephen M., Denkert, Carsten, Loibl, Sibylle, Loi, Sherene, Bartlett, John M. S., Pruneri, Giancarlo, Dillon, Deborah A., Cheang, Maggie C. U., Tutt, Andrew, Hall, Jacqueline A., Kos, Zuzana, Salgado, Roberto ... and International Immuno-Oncology Biomarker Working Group (2020). Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials. npj Breast Cancer, 6 (1) 15. doi: 10.1038/s41523-020-0155-1

  • Divergent mutational processes distinguish hypoxic and normoxic tumours

    Bhandari, Vinayak, Li, Constance H., Bristow, Robert G., Boutros, Paul C., Aaltonen, Lauri A., Abascal, Federico, Abeshouse, Adam, Aburatani, Hiroyuki, Adams, David J., Agrawal, Nishant, Ahn, Keun Soo, Ahn, Sung-Min, Aikata, Hiroshi, Akbani, Rehan, Akdemir, Kadir C., Al-Ahmadie, Hikmat, Al-Sedairy, Sultan T., Al-Shahrour, Fatima, Alawi, Malik, Albert, Monique, Aldape, Kenneth, Alexandrov, Ludmil B., Ally, Adrian, Alsop, Kathryn, Alvarez, Eva G., Amary, Fernanda, Amin, Samirkumar B., Aminou, Brice, Ammerpohl, Ole ... PCAWG Consortium (2020). Divergent mutational processes distinguish hypoxic and normoxic tumours. Nature Communications, 11 (1) 737. doi: 10.1038/s41467-019-14052-x

  • Inferring structural variant cancer cell fraction

    Cmero, Marek, Yuan, Ke, Ong, Cheng Soon, Schröder, Jan, Adams, David J., Anur, Pavana, Beroukhim, Rameen, Boutros, Paul C., Bowtell, David D. L., Campbell, Peter J., Cao, Shaolong, Christie, Elizabeth L., Cun, Yupeng, Dawson, Kevin J., Demeulemeester, Jonas, Dentro, Stefan C., Deshwar, Amit G., Donmez, Nilgun, Drews, Ruben M., Eils, Roland, Fan, Yu, Fittall, Matthew W., Garsed, Dale W., Gerstung, Moritz, Getz, Gad, Gonzalez, Santiago, Ha, Gavin, Haase, Kerstin, Imielinski, Marcin ... von Mering, Christian (2020). Inferring structural variant cancer cell fraction. Nature Communications, 11 (1) 730. doi: 10.1038/s41467-020-14351-8

  • Sex differences in oncogenic mutational processes

    Li, Constance H., Prokopec, Stephenie D., Sun, Ren X., Yousif, Fouad, Schmitz, Nathaniel, Al-Shahrour, Fatima, Atwal, Gurnit, Bailey, Peter J., Biankin, Andrew V., Boutros, Paul C., Campbell, Peter J., Chang, David K., Cooke, Susanna L., Deshpande, Vikram, Faltas, Bishoy M., Faquin, William C., Garraway, Levi, Getz, Gad, Grimmond, Sean M., Haider, Syed, Hoadley, Katherine A., Jiao, Wei, Kaiser, Vera B., Karlić, Rosa, Kato, Mamoru, Kübler, Kirsten, Lazar, Alexander J., Li, Constance H., Louis, David N. ... Lakhani, Sunil R. (2020). Sex differences in oncogenic mutational processes. Nature Communications, 11 (1) 4330. doi: 10.1038/s41467-020-17359-2

  • Lobular carcinoma in situ: diagnostic criteria and molecular correlates

    Sokolova, Anna and Lakhani, Sunil R. (2020). Lobular carcinoma in situ: diagnostic criteria and molecular correlates. Modern Pathology, 34 (S1), 8-14. doi: 10.1038/s41379-020-00689-3

  • Metaplastic breast cancers frequently express immune checkpoint markers FOXP3 and PD-L1

    Kalaw, Emarene, Lim, Malcolm, Kutasovic, Jamie R., Sokolova, Anna, Taege, Lucinda, Johnstone, Kate, Bennett, James, Saunus, Jodi M., Niland, Colleen, Ferguson, Kaltin, Gresshoff, Irma, Bettington, Mark, Pathmanathan, Nirmala, Tse, Gary M., Papadimos, David, Pathmanathan, Rajadurai, Harris, Gavin, Yamaguchi, Rin, Tan, Puay Hoon, Fox, Stephen, O’Toole, Sandra A., Simpson, Peter T., Lakhani, Sunil R. and McCart Reed, Amy E. (2020). Metaplastic breast cancers frequently express immune checkpoint markers FOXP3 and PD-L1. British Journal of Cancer, 123 (11), 1665-1672. doi: 10.1038/s41416-020-01065-3

  • Phenotypic drift in metastatic progression of breast cancer: a case report with histologically heterogeneous lesions that are clonally related

    Kutasovic, Jamie R., McCart Reed, Amy E., Sokolova, Anna, Jayanthan, Janani, Da Silva, Leonard, Simpson, Peter T. and Lakhani, Sunil R. (2020). Phenotypic drift in metastatic progression of breast cancer: a case report with histologically heterogeneous lesions that are clonally related. Clinical Case Reports, 8 (12) ccr3.3257, 2725-2731. doi: 10.1002/ccr3.3257

  • The latest FADS: Functional analysis of GLDN patient variants and classification of GLDN-associated AMC as a type of viable fetal akinesia deformation sequence

    Mis, Emily K., Al-Ali, Samir, Ji, Weizhen, Spencer-Manzon, Michele, Konstantino, Monica, Khokha, Mustafa K., Jeffries, Lauren and Lakhani, Saquib A. (2020). The latest FADS: Functional analysis of GLDN patient variants and classification of GLDN-associated AMC as a type of viable fetal akinesia deformation sequence. American Journal of Medical Genetics Part A, 182 (10), 2291-2296. doi: 10.1002/ajmg.a.61783

  • Using whole-genome sequencing data to derive the homologous recombination deficiency scores

    de Luca, Xavier M., Newell, Felicity, Kazakoff, Stephen H., Hartel, Gunter, McCart Reed, Amy E., Holmes, Oliver, Xu, Qinying, Wood, Scott, Leonard, Conrad, Pearson, John V., Lakhani, Sunil R., Waddell, Nicola, Nones, Katia and Simpson, Peter T. (2020). Using whole-genome sequencing data to derive the homologous recombination deficiency scores. npj Breast Cancer, 6 (1) 33, 33. doi: 10.1038/s41523-020-0172-0

  • Clinicopathologic significance of nuclear HER4 and phospho-YAP(S127) in human breast cancers and matching brain metastases

    Kalita-de Croft, Priyakshi, Lim, Malcolm, Chittoory, Haarika, de Luca, Xavier M., Kutasovic, Jamie R., Day, Bryan W., Al-Ejeh, Fares, Simpson, Peter T., McCart Reed, Amy E., Lakhani, Sunil R. and Saunus, Jodi M. (2020). Clinicopathologic significance of nuclear HER4 and phospho-YAP(S127) in human breast cancers and matching brain metastases. Therapeutic Advances in Medical Oncology, 12, 175883592094625. doi: 10.1177/1758835920946259

  • Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1

    Teo, Wee S., Holliday, Holly, Karthikeyan, Nitheesh, Cazet, Aurélie S., Roden, Daniel L., Harvey, Kate, Konrad, Christina Valbirk, Murali, Reshma, Varghese, Binitha Anu, Thankamony, Archana P., Chan, Chia-Ling, McFarland, Andrea, Junankar, Simon, Ye, Sunny, Yang, Jessica, Nikolic, Iva, Shah, Jaynish S., Baker, Laura A., Millar, Ewan K. A., Naylor, Matthew J., Ormandy, Christopher J., Lakhani, Sunil R., Kaplan, Warren, Mellick, Albert S., O'Toole, Sandra A., Swarbrick, Alexander and Nair, Radhika (2020). Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1. Frontiers in Cell and Developmental Biology, 8 552, 552. doi: 10.3389/fcell.2020.00552

  • Association of sperm-associated antigen 5 and treatment response in patients with estrogen receptor-positive breast cancer

    Abdel-Fatah, Tarek M. A., Ball, Graham R., Thangavelu, Pulari U., Reid, Lynne E., McCart Reed, Amy E., Saunus, Jodi M., Duijf, Pascal H. G., Simpson, Peter T., Lakhani, Sunil R., Pongor, Lorinc, Gyorffy, Balázs, Moseley, Paul M., Green, Andrew R., Pockley, Alan G., Caldas, Carlos, Ellis, Ian O. and Chan, Stephen Y. T. (2020). Association of sperm-associated antigen 5 and treatment response in patients with estrogen receptor-positive breast cancer. JAMA Network Open, 3 (7), e209486. doi: 10.1001/jamanetworkopen.2020.9486

  • Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer

    Baker, Laura A., Holliday, Holly, Roden, Daniel, Krisp, Christoph, Wu, Sunny Z., Junankar, Simon, Serandour, Aurelien A., Mohammed, Hisham, Nair, Radhika, Sankaranarayanan, Geetha, Law, Andrew M. K., McFarland, Andrea, Simpson, Peter T., Lakhani, Sunil, Dodson, Eoin, Selinger, Christina, Anderson, Lyndal, Samimi, Goli, Hacker, Neville F., Lim, Elgene, Ormandy, Christopher J., Naylor, Matthew J., Simpson, Kaylene, Nikolic, Iva, O'Toole, Sandra, Kaplan, Warren, Cowley, Mark J., Carroll, Jason S., Molloy, Mark and Swarbrick, Alexander (2020). Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer. Breast Cancer Research , 22 (1) 63, 63. doi: 10.1186/s13058-020-01306-6

  • Blocking immunosuppressive neutrophils deters pY696-EZH2–driven brain metastases

    Zhang, Lin, Yao, Jun, Wei, Yongkun, Zhou, Zhifen, Li, Ping, Qu, Jingkun, Badu-Nkansah, Akosua, Yuan, Xiangliang, Huang, Yu-Wen, Fukumura, Kazutaka, Mao, Xizeng, Chang, Wei-Chao, Saunus, Jodi, Lakhani, Sunil, Huse, Jason T., Hung, Mien-Chie and Yu, Dihua (2020). Blocking immunosuppressive neutrophils deters pY696-EZH2–driven brain metastases. Science Translational Medicine, 12 (545) eaaz5387, eaaz5387. doi: 10.1126/scitranslmed.aaz5387

  • Digital spatial profiling application in breast cancer: a user’s perspective

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  • Novel compound heterozygous variants in <i>NHLRC2</i> in a patient with FINCA syndrome

    Brodsky, Nina N., Boyarchuk, Oksana, Kovalchuk, Tetyana, Hariyan, Tetyana, Rice, Andrew, Ji, Weizhen, Khokha, Mustafa, Lakhani, Saquib and Lucas, Carrie L. (2020). Novel compound heterozygous variants in NHLRC2 in a patient with FINCA syndrome. Journal of Human Genetics, 65 (10), 911-915. doi: 10.1038/s10038-020-0776-0

  • Tradeoff between metabolic i-proteasome addiction and immune evasion in triple-negative breast cancer

    Adwal, Alaknanda, Kalita-de Croft, Priyakshi, Shakya, Reshma, Lim, Malcolm, Kalaw, Emarene, Taege, Lucinda D., McCart Reed, Amy E., Lakhani, Sunil R., Callen, David F. and Saunus, Jodi M. (2020). Tradeoff between metabolic i-proteasome addiction and immune evasion in triple-negative breast cancer. Life Science Alliance, 3 (7) e201900562, 1-12. doi: 10.26508/lsa.201900562

  • Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

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  • Report on computational assessment of tumor infiltrating lymphocytes from the International Immuno-Oncology Biomarker Working Group

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  • Estrogen and progesterone receptor testing in breast cancer: American society of clinical oncology/college of American pathologists guideline update

    Allison, Kimberly H., Hammond, M. Elizabeth H., Dowsett, Mitchell, McKernin, Shannon E., Carey, Lisa A., Fitzgibbons, Patrick L., Hayes, Daniel F., Lakhani, Sunil R., Chavez-MacGregor, Mariana, Perlmutter, Jane, Perou, Charles M., Regan, Meredith M., Rimm, David L., Symmans, W. Fraser, Torlakovic, Emina E., Varella, Leticia, Viale, Giuseppe, Weisberg, Tracey F., McShane, Lisa M. and Wolff, Antonio C. (2020). Estrogen and progesterone receptor testing in breast cancer: American society of clinical oncology/college of American pathologists guideline update. Archives of Pathology and Laboratory Medicine, 144 (5), 545-563. doi: 10.5858/arpa.2019-0904-SA

  • Estrogen and progesterone receptor testing in breast cancer: ASCO/CAP guideline update

    Allison, Kimberly H., Hammond, M. Elizabeth H., Dowsett, Mitchell, McKernin, Shannon E., Carey, Lisa A., Fitzgibbons, Patrick L., Hayes, Daniel F., Lakhani, Sunil R., Chavez-MacGregor, Mariana, Perlmutter, Jane, Perou, Charles M., Regan, Meredith M., Rimm, David L., Symmans, W. Fraser, Torlakovic, Emina E., Varella, Leticia, Viale, Giuseppe, Weisberg, Tracey F., McShane, Lisa M. and Wolff, Antonio C. (2020). Estrogen and progesterone receptor testing in breast cancer: ASCO/CAP guideline update. Journal of Clinical Oncology, 38 (12), 1346-1366. doi: 10.1200/JCO.19.02309

  • American registry of pathology expert opinions: The spectrum of lobular carcinoma in situ: Diagnostic features and clinical implications

    Schnitt, Stuart J., Brogi, Edi, Chen, Yunn-Yi, King, Tari A. and Lakhani, Sunil R. (2020). American registry of pathology expert opinions: The spectrum of lobular carcinoma in situ: Diagnostic features and clinical implications. Annals of Diagnostic Pathology, 45 151481, 151481. doi: 10.1016/j.anndiagpath.2020.151481

  • Morphologic and Genomic Heterogeneity in the Evolution and Progression of Breast Cancer

    Kutasovic, Jamie R., McCart Reed, Amy E., Sokolova, Anna, Lakhani, Sunil R. and Simpson, Peter T. (2020). Morphologic and Genomic Heterogeneity in the Evolution and Progression of Breast Cancer. Cancers, 12 (4) 848, 848. doi: 10.3390/cancers12040848

  • Pitfalls and controversies in pathology impacting breast cancer management

    Kim, Woo Gyeong, Cummings, Margaret C. and Lakhani, Sunil R. (2020). Pitfalls and controversies in pathology impacting breast cancer management. Expert Review of Anticancer Therapy, 20 (3), 205-219. doi: 10.1080/14737140.2020.1738222

  • The 2019 WHO classification of tumours of the breast

    Hoon Tan, Puay, Ellis, Ian, Allison, Kimberly, Brogi, Edi, Fox, Stephen B., Lakhani, Sunil, Lazar, Alexander J., Morris, Elizabeth A., Sahin, Aysegul, Salgado, Roberto, Sapino, Anna, Sasano, Hironobu, Schnitt, Stuart, Sotiriou, Christos, van Diest, Paul, White, Valerie A., Lokuhetty, Dilani, Cree, Ian A. and WHO Classification of Tumours Editorial Board (2020). The 2019 WHO classification of tumours of the breast. Histopathology, 77 (2) his.14091, 181-185. doi: 10.1111/his.14091

  • Pan-cancer analysis of whole genomes

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  • Non-coding RNAs underlie genetic predisposition to breast cancer

    Moradi Marjaneh, Mahdi, Beesley, Jonathan, O'Mara, Tracy A., Mukhopadhyay, Pamela, Koufariotis, Lambros T., Kazakoff, Stephen, Hussein, Nehal, Fachal, Laura, Bartonicek, Nenad, Hillman, Kristine M., Kaufmann, Susanne, Sivakumaran, Haran, Smart, Chanel E., McCart Reed, Amy E., Ferguson, Kaltin, Saunus, Jodi M., Lakhani, Sunil R., Barnes, Daniel R., Antoniou, Antonis C., Dinger, Marcel E., Waddell, Nicola, Easton, Douglas F., Dunning, Alison M., Chenevix-Trench, Georgia, Edwards, Stacey L. and French, Juliet D. (2020). Non-coding RNAs underlie genetic predisposition to breast cancer. Genome Biology, 21 (1) 7, 7. doi: 10.1186/s13059-019-1876-z

  • Survival and disease characteristics of de novo versus recurrent metastatic breast cancer in a cohort of young patients

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  • The path to a better biomarker: Application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice

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  • Development and validation of a targeted gene sequencing panel for application to disparate cancers

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  • Publisher Correction: Homologous recombination DNA repair defects in PALB2-associated breast cancers (npj Breast Cancer, (2019), 5, 1, (23), 10.1038/s41523-019-0115-9)

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  • LobSig is a multigene predictor of outcome in invasive lobular carcinoma

    McCart Reed, Amy E., Lal, Samir, Kutasovic, Jamie R., Wockner, Leesa, Robertson, Alan, de Luca, Xavier M., Kalita-de Croft, Priyakshi, Dalley, Andrew J., Coorey, Craig P., Kuo, Luyu, Ferguson, Kaltin, Niland, Colleen, Miller, Gregory, Johnson, Julie, Reid, Lynne E., Males, Renique, Saunus, Jodi M., Chenevix-Trench, Georgia, Coin, Lachlan, Lakhani, Sunil R. and Simpson, Peter T. (2019). LobSig is a multigene predictor of outcome in invasive lobular carcinoma. npj Breast Cancer, 5 (1) 18, 18. doi: 10.1038/s41523-019-0113-y

  • Correction: DUB3 and USP7 de-ubiquitinating enzymes control replication inhibitor Geminin: molecular characterization and associations with breast cancer (Oncogene, (2017), 36, 33, (4802-4809), 10.1038/onc.2017.21)

    Hernández-Pérez, S., Cabrera, E., Salido, E., Lim, M., Reid, L., Lakhani, S. R., Khanna, K. K., Saunus, J. M. and Freire, R. (2019). Correction: DUB3 and USP7 de-ubiquitinating enzymes control replication inhibitor Geminin: molecular characterization and associations with breast cancer (Oncogene, (2017), 36, 33, (4802-4809), 10.1038/onc.2017.21). Oncogene, 38 (24), 4886-4886. doi: 10.1038/s41388-019-0753-2

  • ASCO/CAP 2018 breast cancer HER2 testing guidelines: summary of pertinent recommendations for practice in Australia

    Farshid, Gelareh, Bilous, Michael, Morey, Adrienne, Fox, Stephen, Lakhani, Sunil, Loi, Sherene, Bell, Richard and Spillane, Andrew (2019). ASCO/CAP 2018 breast cancer HER2 testing guidelines: summary of pertinent recommendations for practice in Australia. Pathology, 51 (4), 345-348. doi: 10.1016/j.pathol.2019.02.004

  • Proteomic analysis of the breast cancer brain metastasis microenvironment

    Kalita-de Croft, Priyakshi, Straube, Jasmin, Lim, Malcolm, Al-Ejeh, Fares, Lakhani, Sunil R. and Saunus, Jodi M. (2019). Proteomic analysis of the breast cancer brain metastasis microenvironment. International Journal of Molecular Sciences, 20 (10) 2524, 2524. doi: 10.3390/ijms20102524

  • A molecular and morphological deep-dive into metaplastic breast cancers

    McCart Reed, Amy E. and Lakhani, Sunil R. (2019). A molecular and morphological deep-dive into metaplastic breast cancers. Cancer Informatics, 18, 1-2. doi: 10.1177/1176935119850155

  • Whole-genome sequencing reveals clinically relevant insights into the aetiology of familial breast cancers

    Nones, K., Johnson, J., Newell, F., Patch, A. M., Thorne, H., Kazakoff, S. H., de Luca, X. M., Parsons, M. T., Ferguson, K., Reid, L. E., McCart Reed, A. E., Srihari, S., Lakis, V., Davidson, A. L., Mukhopadhyay, P., Holmes, O., Xu, Q., Wood, S., Leonard, C., The Kathleen Cuningham Foundation Consortium for Research into Familial Aspects of Breast Cancer (kConFab), The Australian Breast Cancer Tissue Bank (ABCTB), The Brisbane Breast Bank (BBB), Beesley, J., Harris, J. M., Barnes, D., Degasperi, A., Ragan, M. A., Spurdle, A. B., Khanna, K. K. ... Simpson, P. T. (2019). Whole-genome sequencing reveals clinically relevant insights into the aetiology of familial breast cancers. Annals of Oncology, 30 (7) mdz132, 1071-1079. doi: 10.1093/annonc/mdz132

  • Innovative therapeutic strategies for effective treatment of brain metastases

    Lim, Malcolm, Puttick, Simon, Houston, Zachary H., Thurecht, Kristofer J., Kalita-de Croft, Priyakshi, Mahler, Stephen, Rose, Stephen E., Jeffree, Rosalind L., Mazzieri, Roberta, Dolcetti, Riccardo, Lakhani, Sunil R. and Saunus, Jodi M. (2019). Innovative therapeutic strategies for effective treatment of brain metastases. International Journal of Molecular Sciences, 20 (6) 1280. doi: 10.3390/ijms20061280

  • Secreted cellular prion protein binds doxorubicin and correlates with anthracycline resistance in breast cancer

    Wiegmans, Adrian P., Saunus, Jodi M., Ham, Sunyoung, Lobb, Richard J., Kutasovic, Jamie R., Dalley, Andrew J., Miranda, Mariska, Atkinson, Caroline, Foliaki, Simote T., Ferguson, Kaltin, Niland, Colleen, Johnstone, Cameron N., Lewis, Victoria, Collins, Steven, Lakhani, Sunil R., Al-Ejeh, Fares and Möller, Andreas (2019). Secreted cellular prion protein binds doxorubicin and correlates with anthracycline resistance in breast cancer. JCI Insight, 5 (6). doi: 10.1172/jci.insight.124092

  • The circular RNome of primary breast cancer

    Smid, Marcel, Wilting, Saskia M., Uhr, Katharina, Rodriguez-Gonzalez, F. German, de Weerd, Vanja, Prager-Van der Smissen, Wendy J. C., van der Vlugt-Daane, Michelle, van Galen, Anne, Nik-Zainal, Serena, Butler, Adam, Martin, Sancha, Davies, Helen R., Staaf, Johan, van de Vijver, Marc J., Richardson, Andrea L., MacGrogan, Gaeten, Salgado, Roberto, van den Eynden, Gert G. G. M., Purdie, Colin A., Thompson, Alastair M., Caldas, Carlos, Span, Paul N., Sweep, Fred C. G. J., Simpson, Peter T., Lakhani, Sunil R., Van Laere, Steven, Desmedt, Christine, Paradiso, Angelo, Eyfjord, Jorunn ... Martens, John W. M. (2019). The circular RNome of primary breast cancer. Genome Research, 29 (3), 356-366. doi: 10.1101/gr.238121.118

  • Diff-Quik cytology smears from endobronchial ultrasound transbronchial needle aspiration lymph node specimens as a source of DNA for next-generation sequencing instead of cell blocks

    Fielding, David, Dalley, Andrew J., Bashirzadeh, Farzad, Singh, Mahendra, Nandakumar, Lakshmy, McCart Reed, Amy E., Black, Debra, Kazakoff, Stephen, Pearson, John V., Nones, Katia, Waddell, Nicola, Lakhani, Sunil R. and Simpson, Peter T. (2019). Diff-Quik cytology smears from endobronchial ultrasound transbronchial needle aspiration lymph node specimens as a source of DNA for next-generation sequencing instead of cell blocks. Respiration, 97 (6), 1-14. doi: 10.1159/000495661

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  • Phenotypic and molecular dissection of Metaplastic Breast Cancer and the prognostic implications

    McCart Reed, Amy Ellen, Kalaw, Emarene, Nones, Katia, Bettington, Mark, Lim, Malcolm, Bennett, James, Johnstone, Kate, Kutasovic, Jamie Rose, Saunus, Jodi Marie, Kazakoff, Stephen, Xu, Qinying, Wood, Scott, Holmes, Oliver, Leonard, Conrad, Reid, Lynne Estelle, Black, Debra, Niland, Colleen, Ferguson, Kaltin, Gresshoff, Irma, Raghavendra, Ashwini, Harvey, Kate, Cooper, Caroline, Liu, Cheng, Kalinowski, Lauren, Reid, Andrew Scott, Davidson, Morgan, Pearson, John V, Pathmanathan, Nirmala, Tse, Gary ... Lakhani, Sunil R. (2019). Phenotypic and molecular dissection of Metaplastic Breast Cancer and the prognostic implications. Journal of Pathology, 247 (2), 214-227. doi: 10.1002/path.5184

  • Breast cancer metastasis to gynaecological organs: a clinico‐pathological and molecular profiling study

    Kutasovic, Jamie R., McCart Reed, Amy E., Males, Renique, Sim, Sarah, Saunus, Jodi M., Dalley, Andrew, McEvoy, Christopher R., Dedina, Liana, Miller, Gregory, Peyton, Stephen, Reid, Lynne, Lal, Samir, Niland, Colleen, Ferguson, Kaltin, Fellowes, Andrew P., Al-Ejeh, Fares, Lakhani, Sunil R., Cummings, Margaret C. and Simpson, Peter T. (2019). Breast cancer metastasis to gynaecological organs: a clinico‐pathological and molecular profiling study. The Journal of Pathology: Clinical Research, 5 (1), 25-39. doi: 10.1002/cjp2.118

  • Heritable DNA methylation marks associated with susceptibility to breast cancer

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  • Recent advances in breast cancer research impacting clinical diagnostic practice : Breast cancer research - where are we now?

    McCart Reed, Amy E, Kalita-de Croft, Priyakshi, Kutasovic, Jamie, Saunus, Jodi M and Lakhani, Sunil R (2018). Recent advances in breast cancer research impacting clinical diagnostic practice : Breast cancer research - where are we now?. The Journal of Pathology, 247 (5), 552-562. doi: 10.1002/path.5199

  • CEP55 is a determinant of cell fate during perturbed mitosis in breast cancer

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  • Invasion in breast lesions: the role of the epithelial-stroma barrier

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  • Mixed ductal-lobular carcinomas: evidence for progression from ductal to lobular morphology

    McCart Reed, Amy E., Kutasovic, Jamie R., Nones, Katia, Saunus, Jodi M., Da Silva, Leonard, Newell, Felicity, Kazakoff, Stephen, Melville, Lewis, Jayanthan, Janani, Vargas, Ana Cristina, Reid, Lynne E., Beesley, Jonathan, Chen, Xiao Qing, Patch, Anne Marie, David Clouston, D., Porter, Alan, Evans, Elizabeth, Pearson, John V., Chenevix-Trench, Georgia, Cummings, Margaret C., Waddell, Nic, Lakhani, Sunil R. and Simpson, Peter T. (2018). Mixed ductal-lobular carcinomas: evidence for progression from ductal to lobular morphology. The Journal of Pathology, 244 (4), 460-468. doi: 10.1002/path.5040

  • Characterization of a novel breast cancer cell line derived from a metastatic bone lesion of a breast cancer patient

    Johnson, Julie, Bessette, Darrell C., Saunus, Jodi M., Smart, Chanel E., Song, Sarah, Johnston, Rebecca L., Cocciardi, Sibylle, Rozali, Esdy N., Johnstone, Cameron N., Vargas, Ana Christina, Kazakoff, Stephen H., BioBank, Victorian Cancer, Khanna, Kum Kum, Lakhani, Sunil R., Chenevix-Trench, Georgia, Simpson, Peter T., Nones, Katia, Waddell, Nicola and Al-Ejeh, Fares (2018). Characterization of a novel breast cancer cell line derived from a metastatic bone lesion of a breast cancer patient. Breast Cancer Research and Treatment, 170 (1), 179-188. doi: 10.1007/s10549-018-4719-9

  • Expression of MAGE-A and NY-ESO-1 cancer-testis antigens is enriched in triple-negative invasive breast cancers

    Raghavendra, Ashwini, Kalita-de Croft, Priyakshi, Vargas, Ana Cristina, Smart, Chanel E., Simpson, Peter T., Saunus, Jodi M. and Lakhani, Sunil R. (2018). Expression of MAGE-A and NY-ESO-1 cancer-testis antigens is enriched in triple-negative invasive breast cancers. Histopathology, 73 (1), 68-80. doi: 10.1111/his.13498

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  • Assessing tumor-infiltrating lymphocytes in solid tumors: A practical review for pathologists and proposal for a standardized method from the international immuno-oncology biomarkers working group: Part 2: TILs in melanoma, gastrointestinal tract carcinomas, non-small cell lung carcinoma and mesothelioma, endometrial and ovarian carcinomas, squamous cell carcinoma of the head and neck, genitourinary carcinomas, and primary brain tumors

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  • SASH1 mediates sensitivity of breast cancer cells to chloropyramine and is associated with prognosis in breast cancer

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  • The cancer genetics and pathology of male breast cancer

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  • TGFβ isoforms and receptors mRNA expression in breast tumours: Prognostic value and clinical implications

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  • Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib

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  • An evaluation of the prognostic model PREDICT using the POSH cohort of women aged ≤40 years at breast cancer diagnosis

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  • Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines

    Momeny, Majid, Saunus, Jodi M., Marturana, Flavia, McCart Reed, Amy E., Black, Debra, Sala, Gianluca, Iacobelli, Stefano, Holland, Jane D., Yu, Dihua, Da Silva, Leonard, Simpson, Peter T., Khanna, Kum Kum, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2015). Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines. Oncotarget, 6 (6), 3932-3946. doi: 10.18632/oncotarget.2846

  • Invasive lobular carcinoma of the breast: morphology, biomarkers and 'omics

    McCart Reed, Amy E., Kutasovic, Jamie R., Lakhani, Sunil R. and Simpson, Peter T. (2015). Invasive lobular carcinoma of the breast: morphology, biomarkers and 'omics. Breast Cancer Research, 17 (12) 12, 1-11. doi: 10.1186/s13058-015-0519-x

  • ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype

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  • Obesity and the outcome of young breast cancer patients in the UK: The POSH study

    Copson, E. R., Cutress, R. I., Maishman, T., Eccles, B. K., Gerty, S., Stanton, L., Altman, D. G., Durcan, L., Wong, C., Simmonds, P. D., Jones, L., Eccles, D. M., POSH Study Steering Group and Lakhani, S. (2015). Obesity and the outcome of young breast cancer patients in the UK: The POSH study. Annals of Oncology, 26 (1), 101-112. doi: 10.1093/annonc/mdu509

  • Erratum: Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer

    Al-Ejeh, F, Simpson, P T, Saunus, J M, Klein, K, Kalimutho, M, Shi, W, Miranda, M, Kutasovic, J, Raghavendra, A, Madore, J, Reid, L, Krause, L, Chenevix-Trench, G, Lakhani, S R and Khanna, K K (2014). Erratum: Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer. Oncogenesis, 3 (10) e124, e124-e124. doi: 10.1038/oncsis.2014.41

  • Is the one-step nucleic acid amplification assay better for intra-operative assessment of breast sentinel nodes?

    Bettington, Mark, Lakhani, Sunil R. and Ung, Owen A. (2014). Is the one-step nucleic acid amplification assay better for intra-operative assessment of breast sentinel nodes?. ANZ Journal of Surgery, 84 (10), 725-729. doi: 10.1111/ans.12497

  • Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

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  • COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatment

    Generali, D., Buffa, F. M., Deb, S., Cummings, M., Reid, L. E., Taylor, M., Andreis, D., Allevi, G., Ferrero, G., Byrne, D., Martinotti, M., Bottini, A., Harris, A. L., Lakhani, S. R. and Fox, S. B. (2014). COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatment. British Journal of Cancer, 111 (1), 46-54. doi: 10.1038/bjc.2014.236

  • Molecular classification of breast cancer

    Vuong, Darina, Simpson, Peter T., Green, Benjamin, Cummings, Margaret C. and Lakhani, Sunil R. (2014). Molecular classification of breast cancer. Virchows Archiv, 465 (1), 1-14. doi: 10.1007/s00428-014-1593-7

  • Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer

    Al-Ejeh, F., Simpson, P. T., Sanus, J. M., Klein, K., Kalimutho, M., Shi, W., Miranda, M., Kutasovic, J., Raghavendra, A., Madore, J., Reid, L., Krause, L., Chenevix-Trench, G., Lakhani, S. R. and Khanna, K. K. (2014). Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer. Oncogenesis, 3 (4) e100, 1-12. doi: 10.1038/oncsis.2014.14

  • Processed pseudogenes acquired somatically during cancer development

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  • Multifactorial likelihood assessment of BRCA1 and BRCA2 missense variants confirms that BRCA1:c.122A>G(p.His41Arg) is a pathogenic mutation

    Whiley, Phillip J., Parsons, Michael T., Leary, Jennifer, Tucker, Kathy, Warwick, Linda, Dopita, Belinda, Thorne, Heather, Lakhani, Sunil R., Goldgar, David E., Brown, Melissa A. and Spurdle, Amanda B. (2014). Multifactorial likelihood assessment of BRCA1 and BRCA2 missense variants confirms that BRCA1:c.122A>G(p.His41Arg) is a pathogenic mutation. PloS One, 9 (1) e86836, 1-10. doi: 10.1371/journal.pone.0086836

  • Ethnicity and outcome of young breast cancer patients in the United Kingdom: the POSH study

    Copson, E., Maishman, T., Gerty, S., Eccles, B., Stanton, L., Cutress, R. I., Altman, D. G., Durcan, L., Simmonds, P., Jones, L., Tapper W., Eccles, D., POSH study steering group and Lakhani, Sunil (2014). Ethnicity and outcome of young breast cancer patients in the United Kingdom: the POSH study. British Journal of Cancer, 110 (1), 230-241. doi: 10.1038/bjc.2013.650

  • Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer

    Al-Ejeh, Fares, Miranda, Mariska, Shi,Wei, Simpson, Peter T., Song, Sarah, Vargas, Ana Cristina, Saunus, Jodi M., Smart, Chanel E., Mariasegaram, Mythily, Wiegmans, Adrian P., Chenevix-Trench, Georgia, Lakhani, Sunil R. and Khanna, Kum Kum (2014). Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer. Oncotarget, 5 (10), 3145-3158. doi: 10.18632/oncotarget.1865

  • Metastatic progression of breast cancer: Insights from 50 years of autopsies

    Cummings, Margaret C., Simpson, Peter T., Reid, Lynne E., Jayanthan, Janani, Skerman, Joanna, Song, Sarah, McCart Reed, Amy E., Kutasovic, Jamie R., Morey, Adrienne L., Marquart, Louise, O'Rourke, Peter and Lakhani, Sunil R. (2014). Metastatic progression of breast cancer: Insights from 50 years of autopsies. Journal of Pathology, 232 (1), 23-31. doi: 10.1002/path.4288

  • Mutations in EGFR, BRAF and RAS are rare in triple-negative and basal-like breast cancers from Caucasian women

    Tilch, E., Seidens, T., Cocciardi, S., Reid, L. E., Byrne, D., Simpson, P. T., Vargas, A. C., Cummings, M. C., Fox, S. B., Lakhani, S. R. and Chenevix Trench, G. (2014). Mutations in EGFR, BRAF and RAS are rare in triple-negative and basal-like breast cancers from Caucasian women. Breast Cancer Research and Treatment, 143 (2), 385-392. doi: 10.1007/s10549-013-2798-1

  • Rad51 supports triple negative breast cancer metastasis

    Wiegmans, Adrian P., Al-Ejeh, Fares, Chee, Nicole, Yap, Pei-Yi, Gorski, Julia J., Da Silva, Leonard, Bolderson, Emma, Chenevix-Trench, Georgia, Anderson, Robin, Simpson, Peter T., Lakhani, Sunil R. and Khanna, Kum Kum (2014). Rad51 supports triple negative breast cancer metastasis. Oncotarget, 5 (10), 3261-3272. doi: 10.18632/oncotarget.1923

  • miR-139-5p is a regulator of metastatic pathways in breast cancer

    Krishnan, Keerthana, Steptoe, Anita, Martin, Hilary, Pattabiraman, Diwakar R., Nones, Katia, Waddell, Nicola, Mariasegaram, Mythily, Simpson, Peter T., Lakhani, Sunil R., Vlassov, Alexander, Grimmond, Sean M. and Cloonan, Nicole (2013). miR-139-5p is a regulator of metastatic pathways in breast cancer. RNA, 19 (12), 1767-1780. doi: 10.1261/rna.042143.113

  • c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer

    Nair, R., Roden, D. L., Teo, W. S., McFarland, A., Junankar, S., Ye, S., Nguyen, A., Yang, J., Nikolic, I., Hui, M., Morey, A., Shah, J., Pfefferle, A. D., Usary, J., Selinger, C., Baker, L. A., Armstrong, N., Cowley, M. J., Naylor, M. J., Ormandy, C. J., Lakhani, S. R., Herschkowitz, J. I., Perou, C. M., Kaplan, W., O'Toole, S. A. and Swarbrick, A. (2013). c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer. Oncogene, 33 (30), 3992-4002. doi: 10.1038/onc.2013.368

  • Signatures of mutational processes in human cancer

    Alexandrov, Ludmil B., Nik-Zainal, Serena, Wedge, David C., Aparicio, Samuel A. J. R., Behjati, Sam, Biankin, Andrew V., Bignell, Graham R., Bolli, Niccolo, Borg, Ake, Borresen-Dale, Anne-Lise, Boyault, Sandrine, Burkhardt, Birgit, Butler, Adam P., Caldas, Carlos, Davies, Helen R., Desmedt, Christine, Eils, Roland, Eyfjord, Jorunn Erla, Foekens, John A., Greaves, Mel, Hosoda, Fumie, Hutter, Barbara, Ilicic, Tomislav, Imbeaud, Sandrine, Imielinsk, Marcin, Jaeger, Natalie, Jones, David T. W., Jones, David, Knappskog, Stian ... Stratton, Michael R. (2013). Signatures of mutational processes in human cancer. Nature, 500 (7463), 415-421. doi: 10.1038/nature12477

  • Intraoperative imprint cytology for breast cancer sentinel nodes: is it worth it?

    Richards, Angela D. M., Lakhani, Sunil R., James, Daniel T. and Ung, Owen A. (2013). Intraoperative imprint cytology for breast cancer sentinel nodes: is it worth it?. ANZ Journal of Surgery, 83 (7-8), 539-544. doi: 10.1111/j.1445-2197.2012.06293.x

  • Mammographic and ultrasound features of invasive lobular carcinoma of the breast

    Porter, Alan J., Evans, Elizabeth B., Foxcroft, Loani M., Simpson, Peter T. and Lakhani, Sunil R. (2013). Mammographic and ultrasound features of invasive lobular carcinoma of the breast. Journal of Medical Imaging and Radiation Oncology, 58 (1), 1-10. doi: 10.1111/1754-9485.12080

  • In vitro analysis of breast cancer cell line tumourspheres and primary human breast epithelia mammospheres demonstrates inter- and intrasphere heterogeneity

    Smart, Chanel E., Morrison, Brian J., Saunus, Jodi M., Vargas, Ana Cristina, Keith, Patricia, Reid, Lynne, Wockner, Leesa, Amiri, Marjan Askarian, Sarkar, Debina, Simpson, Peter T., Clarke, Catherine, Schmidt, Chris W., Reynolds, Brent A., Lakhani, Sunil R. and Lopez, J. Alejandro (2013). In vitro analysis of breast cancer cell line tumourspheres and primary human breast epithelia mammospheres demonstrates inter- and intrasphere heterogeneity. PloS One, 8 (6) e64388, e64388. doi: 10.1371/journal.pone.0064388

  • Evaluating the repair of DNA derived from formalin-fixed paraffin-embedded tissues prior to genomic profiling by SNP-CGH analysis

    Hosein, Abdel Nasser, Song, Sarah, McCart Reed, Amy E., Jayanthan, Janani, Reid, Lynne E., Kutasovic, Jamie R., Cummings, Margaret C., Waddell, Nic, Lakhani, Sunil R., Chenevix-Trench, Georgia and Simpson, Peter T. (2013). Evaluating the repair of DNA derived from formalin-fixed paraffin-embedded tissues prior to genomic profiling by SNP-CGH analysis. Laboratory Investigation, 93 (6), 701-710. doi: 10.1038/labinvest.2013.54

  • Treatment of triple-negative breast cancer using anti-EGFR-directed radioimmunotherapy combined with radiosensitizing chemotherapy and PARP inhibitor

    Al-Ejeh, Fares, Shi, Wei, Miranda, Mariska, Simpson, Peter T., Vargas, Ana Cristina, Song, Sarah, Wiegmans, Adrian P., Swarbrick, Alex, Welm, Alana L., Brown, Michael P., Chenevix-Trench, Georgia, Lakhani, Sunil R. and Khanna, Kum Kum (2013). Treatment of triple-negative breast cancer using anti-EGFR-directed radioimmunotherapy combined with radiosensitizing chemotherapy and PARP inhibitor. Journal of Nuclear Medicine, 54 (6), 913-921. doi: 10.2967/jnumed.112.111534

  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Bojesen, Stig E., Pooley, Karen A., Johnatty, Sharon E., Beesley, Jonathan, Michailidou, Kyriaki, Tyrer, Jonathan P., Edwards, Stacey L., Pickett, Hilda A., Shen, Howard C., Smart, Chanel E., Hillman, Kristine M., Mai, Phuong L., Lawrenson, Kate, Stutz, Michael D., Lu, Yi, Karevan, Rod, Woods, Nicholas, Johnston, Rebecca L., French, Juliet D., Chen, Xiaoqing, Weischer, Maren, Nielsen, Sune F., Maranian, Melanie J., Ghoussaini, Maya, Ahmed, Shahana, Baynes, Caroline, Bolla, Manjeet K., Wang, Qin, Dennis, Joe ... Genetic Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers (GEMO) (2013). Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nature Genetics, 45 (4), 371-384. doi: 10.1038/ng.2566

  • MicroRNA-182-5-p targets a network of genes involved in DNA repair

    Krishnan, Keerthana, Steptoe, Anita L., Martin, Hilary C., Wani, Shivangi, Nones, Katia, Waddell, Nic, Mariasegaram, Mythily, Simpson, Peter T., Lakhani, Sunil R., Gabrielli, Brian, Vlassov, Alexander, Cloonan, Nicole and Grimmond, Sean M. (2013). MicroRNA-182-5-p targets a network of genes involved in DNA repair. RNA, 19 (2), 230-242. doi: 10.1261/rna.034926.112

  • Lobular neoplasia of the breast revisited with emphasis on the role of e-cadherin immunohistochemistry

    Dabbs, David J., Schnitt, Stuart J., Geyer, Felipe C., Weigelt, Britta, Baehner, Frederick L., Decker, Thomas, Eusebi, Vincenzo, Fox, Stephen B., Ichihara, Shu, Lakhani, Sunil R., Palacios, Jose, Rakha, Emad, Richardson, Andrea L., Schmitt, Fernando C., Tan, Puay-Hoon, Tse, Gary M., Vincent-Salomon, Anne, Ellis, Ian O., Badve, Sunil and Reis-Filho, Jorge S. (2013). Lobular neoplasia of the breast revisited with emphasis on the role of e-cadherin immunohistochemistry. American Journal of Surgical Pathology, 37 (7), e1-e11. doi: 10.1097/PAS.0b013e3182918a2b

  • Expression profiling of archival tumors for long-term health studies

    Waldron, Levi, Ogino, Shuji, Hoshida, Yujin, Shima, Kaori, Reed, Amy E. McCart, Simpson, Peter T., Baba, Yoshifumi, Nosho, Katsuhiko, Segata, Nicola, Vargas, Ana Cristina, Cummings, Margaret C., Lakhani, Sunil R., Kirkner, Gregory J., Giovannucci, Edward, Quackenbush, John, Golub, Todd R., Fuchs, Charles S., Parmigiani, Giovanni and Huttenhower, Curtis (2012). Expression profiling of archival tumors for long-term health studies. Clinical Cancer Research, 18 (22), 6136-6146. doi: 10.1158/1078-0432.CCR-12-1915

  • Morphological and molecular analysis of a breast cancer cluster at the ABC Studio in Toowong

    Waddell, N., Stein, S. R., Wagner, S. A., Bennett, I., Djougarian, A., Melana, S., Jaffer, S., Holland, J. F., Pogo, B. G. T., Gonda, T. J., Brown, M. A., Leo, P., Saunders, N. A., McMillan, N. A., Cocciardi, S., Vargas, A. C., Lakhani, S. R., Chenevix-Trench, G., Newman, B. and Francis, G. D. (2012). Morphological and molecular analysis of a breast cancer cluster at the ABC Studio in Toowong. Pathology, 44 (5), 469-472. doi: 10.1097/PAT.0b013e3283559e67

  • Calcium channel TRPV6 as a potential therapeutic target in estrogen receptor negative breast cancer

    Peters, Amelia A., Simpson, Peter T., Bassett, Johnathon J., Lee, Jane M., Da Silva, Leonard, Reid, Lynne E., Song, Sarah, Parat, Marie-Odile, Lakhani, Sunil R., Kenny, Paraic A., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2012). Calcium channel TRPV6 as a potential therapeutic target in estrogen receptor negative breast cancer. Molecular Cancer Therapeutics, 11 (10), 2158-2168. doi: 10.1158/1535-7163.MCT-11-0965

  • Expression and function of the protein tyrosine phosphatase receptor J (PTPRJ) in normal mammary epithelial cells and breast tumors

    Smart, Chanel E., Askarian Amiri, Marjan E., Wronski, Ania, Dinger, Marcel E., Crawford, Joanna, Ovchinnikov, Dmitry A., Vargas, Ana Cristina, Reid, Lynne, Simpson, Peter T., Song, Sarah, Wiesner, Christiane, French, Juliet D., Dave, Richa K., da Silva, Leonard, Purdon, Amy, Andrew, Megan, Mattick, John S., Lakhani, Sunil R., Brown, Melissa A. and Kellie, Stuart (2012). Expression and function of the protein tyrosine phosphatase receptor J (PTPRJ) in normal mammary epithelial cells and breast tumors. PLoS One, 7 (7) e40742, e40742.1-e40742.13. doi: 10.1371/journal.pone.0040742

  • The landscape of cancer genes and mutational processes in breast cancer

    Stephens, Philip J., Tarpey, Patrick S., Davies, Helen, Van Loo, Peter, Greenman, Chris, Wedge, David C., Nik-Zainal, Serena, Martin, Sancha, Varela, Ignacio, Bignell, Graham R., Yates, Lucy R., Papaemmanuil, Elli, Beare, David, Butler, Adam, Cheverton, Angela, Gamble, John, Hinton, Jonathan, Jia, Mingming, Jayakumar, Alagu, Jones, David, Latimer, Calli, Lau, KingWai, McLaren, Stuart, McBride, David J., Menzies, Andrew, Mudie, Laura, Raine, Laura, Rad, Roland, Chapman, Michael Spencer ... Stratton, Michael R. (2012). The landscape of cancer genes and mutational processes in breast cancer. Nature, 486 (7403), 400-U133. doi: 10.1038/nature11017

  • Observer agreement comparing the use of virtual slides with glass slides in the pathology review component of the POSH breast cancer cohort study

    Shaw, Emily Clare, Hanby, Andrew M., Wheeler, Kevin, Shaaban, Abeer M ., Poller, David, Barton, Sheila, Treanor, Darren, Fulford, Laura, Walker, Rosemary A., Ryan, Deirdre, Lakhani, Sunil R., Wells, Clive A., Roche, Heather, Theaker, Jeffrey M., Ellis, Ian O, Jones, J. Louise and Eccles, Diana M. (2012). Observer agreement comparing the use of virtual slides with glass slides in the pathology review component of the POSH breast cancer cohort study. Journal of Clinical Pathology, 65 (5), 403-408. doi: 10.1136/jclinpath-2011-200369

  • Molecular pathology of pre-invasive breast disease in the screening setting: Application in diagnosis and management

    McCart Reed, Amy E., Cummings, Margaret C., Lakhani, Sunil R. and Simpson, Peter T. (2012). Molecular pathology of pre-invasive breast disease in the screening setting: Application in diagnosis and management. Diagnostic Histopathology, 18 (2), 64-69. doi: 10.1016/j.mpdhp.2011.11.006

  • Tubular breast carcinoma: An argument against treatment de-escalation

    Hansen, Carmen J., Kenny, Liz, Lakhani, Sunil R., Ung, Owen, Keller, Jacqui, Tripcony, Lee, Cheuk, Robyn, Grogan, Michelle, Vargas, Ana Cristina and Martin, Jarad (2012). Tubular breast carcinoma: An argument against treatment de-escalation. Journal of Medical Imaging and Radiation Oncology, 56 (1), 116-122. doi: 10.1111/j.1754-9485.2011.02330.x

  • Gene expression profiling of tumour epithelial and stromal compartments during breast cancer progression

    Vargas, Ana Cristina, McCart Reed, Amy E., Waddell, Nic, Lane, Annette, Reid, Lynne E., Smart, Chanel E., Cocciardi, Sibylle, da Silva, Leonard, Song, Sarah, Chenevix-Trench, Georgia, Simpson Peter T. and Lakhani, Sunil R. (2012). Gene expression profiling of tumour epithelial and stromal compartments during breast cancer progression. Breast Cancer Research and Treatment, 135 (1), 153-165. doi: 10.1007/s10549-012-2123-4

  • Molecular classification of breast carcinoma

    Alizart, Michelle, Saunus, Jodi, Cummings, Margaret and Lakhani, Sunil R. (2012). Molecular classification of breast carcinoma. Diagnostic Histopathology, 18 (3), 97-103. doi: 10.1016/j.mpdhp.2011.12.003

  • Extramedullary megakaryoblastic leukaemia with massive generalised infiltration

    Vargas, Ana Cristina, O'Brien, Blake, Marquez, Maria Luisa, Ortiz-Hidalgo, Carlos and Lakhani, Sunil R. (2011). Extramedullary megakaryoblastic leukaemia with massive generalised infiltration. Pathology, 43 (5), 517-519. doi: 10.1097/PAT.0b013e32834864ba

  • Rare variants in the ATM gene and risk of breast cancer

    Goldgar, David E., Healey, Sue, Dowty, James G., Da Silva, Leonard, Chen, Xiaoqing, Spurdle, Amanda B., Terry, Mary B., Daly, Mary J., Buys, Saundra M., Southey, Melissa C., Andrulis, Irene, John, Esther M., Breast Cancer Family Registry, Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer, Khanna, Kum K., Hopper, John L., Oefner, Peter J., Lakhani, Sunil and Chenevix-Trench, Georgia (2011). Rare variants in the ATM gene and risk of breast cancer. Breast Cancer Research, 13 (4) R73, R73-1-R73-9. doi: 10.1186/bcr2919

  • Splicing and multifactorial analysis of intronic BRCA1 and BRCA2 sequence variants identifies clinically significant splicing aberrations up to 12 nucleotides from the intron/exon boundary

    Whiley, Phillip J., Guidugli, Lucia, Walker, Logan C., Healey, Sue, Thompson, Bryony A., Lakhani, Sunil R., Da Silva, Leonard M., kConFab Investigators, Tavtigian, Sean V., Goldgar, David E., Brown, Melissa A., Couch, Fergus J. and Spurdle, Amanda B. (2011). Splicing and multifactorial analysis of intronic BRCA1 and BRCA2 sequence variants identifies clinically significant splicing aberrations up to 12 nucleotides from the intron/exon boundary. Human Mutation, 32 (6), 678-687. doi: 10.1002/humu.21495

  • Tumor heterogeneity in a follicular carcinoma of thyroid: a study by comparative genomic hybridization

    Da Silva, Leonard, James, Daniel, Simpson, Peter T., Walker, Daniel, Vargas, Ana Cristina, Jayanthan, Janani, Lakhani, Sunil R. and McNicol, Anne Marie (2011). Tumor heterogeneity in a follicular carcinoma of thyroid: a study by comparative genomic hybridization. Endocrine Pathology, 22 (2), 103-107. doi: 10.1007/s12022-011-9154-y

  • Breast cancer stem cells: Treatment resistance and therapeutic opportunities

    AL-Ejeh, Fares, Smart, Chanel E., Morrison, Brian J., Chenevix-Trench, Georgia, Lopez, J. Alejandro, Lakhani, Sunil R., Brown, Michael P. and Khanna, Kum Kum (2011). Breast cancer stem cells: Treatment resistance and therapeutic opportunities. Carcinogenesis, 32 (5), 650-658. doi: 10.1093/carcin/bgr028

  • SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer

    Askarian-Amiri, Marjan E., Crawford, Joanna, French, Juliet D., Smart, Chanel E., Smith, Martin A., Clark, Michael B., Ru, Kelin, Mercer, Tim R., Thompson, Ella R., Lakhani, Sunil R., Vargas, Ana C., Campbell, Ian G., Brown, Melissa A., Dinger, Marcel E. and Mattick, John S. (2011). SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer. RNA, 17 (5), 878-891. doi: 10.1261/rna.2528811

  • Phenotype-genotype correlation in familial breast cancer

    Vargas, A.C., Reis, J.S. and Lakhani, S.R. (2011). Phenotype-genotype correlation in familial breast cancer. Journal of Mammary Gland Biology and Neoplasia, 16 (1), 27-40. doi: 10.1007/s10911-011-9204-6

  • Analysis of brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit

    Smart, C.E., Wronski, A., French, J.D., Edwards, S.L., Asselin-Labat, M.L., Waddell, N., Peters, K., Brewster, B.L., Brooks, K., Simpson, K., Manning, N., Lakhani, S.R., Grimmond, S., Lindeman, G.J., Visvader, J.E. and Brown, M.A. (2011). Analysis of brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit. Oncogene, 30 (13), 1597-1607. doi: 10.1038/onc.2010.538

  • Application of molecular findings to the diagnosis and management of breast disease: Recent advances and challenges

    Simpson, Peter T., Vargas, Ana Christina, Al-Ejeh, Fares, Khanna, Kum Kum, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2011). Application of molecular findings to the diagnosis and management of breast disease: Recent advances and challenges. Human Pathology, 42 (2), 153-165. doi: 10.1016/j.humpath.2010.07.008

  • Basal-like and triple-negative breast cancers: A critical review with an emphasis on the implications for pathologists and oncologists

    Badve, Sunil, Dabbs, David J., Schnitt, Stuart J., Baehner, Frederick L., Decker, Thomas, Eusebi, Vincenzo, Fox, Stephen B., Ichihara, Shu, Jacquemier, Jocelyne, Lakhani, Sunil R., Palacios, Jose, Rakha, Emad A., Richardson, Andrea L., Schmitt, Fernando C., Tan, Puay-Hoon, Tse, Gary M., Weigelt, Britta, Ellis, Ian O. and Reis-Filho, Jorge S. (2011). Basal-like and triple-negative breast cancers: A critical review with an emphasis on the implications for pathologists and oncologists. Modern Pathology, 24 (2), 157-167. doi: 10.1038/modpathol.2010.200

  • Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers

    Ramus, Susan J., Kartsonaki, Christiana, Gayther, Simon A., Pharoah, Paul D. P., Sinilnikova, Olga M., Beesley, Jonathan, Chen, Xiaoqing, McGuffog, Lesley, Healey, Sue, Couch, Fergus J., Wang, Xianshu, Fredericksen, Zachary, Peterlongo, Paolo, Manoukian, Siranoush, Peissel, Bernard, Zaffaroni, Daniela, Roversi, Gaia, Barile, Monica, Viel, Alessandra, Allavena, Anna, Ottini, Laura, Papi, Laura, Gismondi, Viviana, Capra, Fabio, Radice, Paolo, Greene, Mark H., Mai, Phuong L., Andrulis, Irene L., Glendon, Gord ... Lakhani, Sunil (2011). Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers. Journal of the National Cancer Institiute, 103 (2), 105-116. doi: 10.1093/jnci/djq494

  • Molecular aspects of breast cancer metastasis to the brain

    Saunus, Jodi M., Momeny, Majid, Simpson, Peter T., Da Silva, Leonard and Lakhani, Sunil R. (2011). Molecular aspects of breast cancer metastasis to the brain. Genetics Research International, 2011, 219189-1-219189-9. doi: 10.4061/2011/219189

  • Molecular classification of breast cancer: Is it time to pack up our microscopes?

    Cummings, Margaret C., Chambers, Rachael, Simpson, Peter T. and Lakhani, Sunil R. (2011). Molecular classification of breast cancer: Is it time to pack up our microscopes?. Pathology, 43 (1), 1-8. doi: 10.1097/PAT.0b013e328341e0b5

  • The contribution of breast cancer pathology to statistical models to predict mutation risk in BRCA carriers

    Vargas, AC, Da Silva, L and Lakhani, SR (2010). The contribution of breast cancer pathology to statistical models to predict mutation risk in BRCA carriers. Familial Cancer, 9 (4), 545-553. doi: 10.1007/s10689-010-9362-5

  • Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomes

    Al-Ejeh, F., Kumar, R., Wiegmans, A., Lakhani, S.R., Brown, M.P. and Khanna, K.K. (2010). Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomes. Oncogene, 29 (46), 6085-6098. doi: 10.1038/onc.2010.407

  • DNA methylation profiling of phyllodes and fibroadenoma tumours of the breast

    Huang, Katie T., Dobrovic, Alexander, Yan, Max, Karim, Rooshdiya Z., Lee, C. Soon, Lakhani, Sunil R. and Fox, Stephen B. (2010). DNA methylation profiling of phyllodes and fibroadenoma tumours of the breast. Breast Cancer Research and Treatment, 124 (2), 555-565. doi: 10.1007/s10549-010-0970-4

  • A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population

    Antoniou, Antonis C., Wang, Xianshu, Fredericksen, Zachary S., McGuffog, Lesley, Tarrell, Robert, Sinilnikova, Olga M., Healey, Sue, Morrison, Jonathan, Kartsonaki,Christiana, Lesnick, Timothy, Ghoussaini, Maya, Barrowdale, Daniel, Peock, Susan, Cook, Margaret, Oliver, Clare, Frost, Debra, Eccles, Diana, Evans, D. Gareth, Eeles, Ros, Izatt, Louise, Chu, Carol, Douglas, Fiona, Paterson, Joan, Stoppa-Lyonnet, Dominique, Houdayer, Claude, Mazoyer, Sylvie, Giraud, Sophie, Lasset, Christine, Remenieras, Audrey ... Lakhani, Sunil (2010). A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population. Nature Genetics, 42 (10), 885-892. doi: 10.1038/ng.669

  • Common genetic variants and modification of penetrance of BRCA2-associated breast cancer

    Mia M. Gaudet, Tomas Kirchhoff, Todd Green, Joseph Vijai, Joshua M. Korn, Candace Guiducci, Ayellet V. Segre, Kate McGee, Lesley McGuffog, Christiana Kartsonaki, Jonathan Morrison, Sue Healey, Olga M. Sinilnikova, Dominique Stoppa-Lyonnet, Sylvie Mazoyer, Marion Gauthier-Villars, Hagay Sobol, Michel Longy, Marc Frenay, GEMO Study Collaborators, Frans B. L. Hogervorst, Matti a. Rookus, J. Margriet Collee, Nicoline Hoogerbrugge, Kees E. P. van Roozendaal, HEBON Study Collaborators, Marion Piedmonte, Wendy Rubinstein, Stacy Nerenstone ... Lakhani, Sunil (2010). Common genetic variants and modification of penetrance of BRCA2-associated breast cancer. PLoS Genetics, 6 (10), e1001183-1-e1001183-12. doi: 10.1371/journal.pgen.1001183

  • Subtypes of familial breast tumours revealed by expression and copy number profiling

    Waddell, N, Arnold, J, Cocciardi, S, da Silva, L, Marsh, A, Riley, J, Johnstone, CN, Orloff, M, Assie, G, Eng, C, Reid, L, Keith, P, Yan, M, Fox, S, Devilee, P, Godwin, AK, Hogervorst, FBL, Couch, F, Grimmond, S, Flanagan, JM, Khanna, K, Simpson, PT, Lakhani, SR, Chenevix-Trench, G and kConFab Investigators (2010). Subtypes of familial breast tumours revealed by expression and copy number profiling. Breast Cancer Research And Treatment, 123 (3), 661-677. doi: 10.1007/s10549-009-0653-1

  • Gene expression profiling of formalin-fixed, paraffin-embedded familial breast tumours using the whole genome-DASL assay

    Waddell, Nic, Cocciardi, Sibylle, Johnson, Julie, Healey, Sue, Marsh, Anna, Riley, Joan, da Silva, Leonard, Vargas, Ana Cristina, Reid, Lynne, Simpson, Peter T., Lakhani, Sunil R. and Chenevix-Trench, Georgia (2010). Gene expression profiling of formalin-fixed, paraffin-embedded familial breast tumours using the whole genome-DASL assay. Journal of Pathology, 221 (4), 452-461. doi: 10.1002/path.2728

  • Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers

    Wang, Xianshu, Pankratz, V. Shane, Fredericksen, Zachary, Tarrell, Robert, Karaus, Mary, McGuffog, Lesley, Pharaoh, Paul D.P., Ponder, Bruce A.J., Dunning, Alison M., Peock, Susan, Cook, Margaret, Oliver, Clare, Frost, Debra, EMBRACE, Sinilnikova, Olga M., Stoppa-Lyonnet, Dominique, Mazoyer, Sylvie, Houdayer, Claude, GEMO, Hogervorst, Frans B.L., Hooning, Maartje J., Ligtenberg, Marjolijn J., HEBON, Spurdle, Amanda, Chenevix-Trench, Georgia, kConFab, Schmutzler, Rita K., Wappenschmidt, Barbara, Engel, Christoph ... Lakhani, Sunil (2010). Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers. Human Molecular Genetics, 19 (14), 2886-2897. doi: 10.1093/hmg/ddq174

  • Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell lines

    Alexopoulou, Annika N., Leao, Maria, Caballero, Otavia L., Da Silva, Leonard, Reid, Lynne, Lakhani, Sunil R., Simpson, Andrew J., Marshall, John F., Neville, A. Munro and Jat, Parmjit S. (2010). Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell lines. Breast Cancer Research, 12 (4) R51, R51-1-R51-17. doi: 10.1186/bcr2610

  • Detection of Splicing Aberrations Caused by BRCA1 and BRCA2 Sequence Variants Encoding Missense Substitutions: Implications for Prediction of Pathogenicity

    Walker, Logan C., Whiley, Phillip J., Couch, Fergus J., Farrugia, Daniel J., Healey, Sue, Eccles, Diana M., Lin, Feng, Butler, Samantha A., Goff, Sheila A., Thompson, Bryony A., Lakhani, Sunil R., Da Silva, Leonard M., Tavtigian, Sean V., Goldgar, David E., Brown, Melissa A. and Spurdle, Amanda B. (2010). Detection of Splicing Aberrations Caused by BRCA1 and BRCA2 Sequence Variants Encoding Missense Substitutions: Implications for Prediction of Pathogenicity. Human Mutation, 31 (6), E1484-E1505. doi: 10.1002/humu.21267

  • Incorporating tumour pathology information into breast cancer risk prediction algorithms

    Mavaddat, Nasim, Rebbeck, Timothy R., Lakhani, Sunil R., Easton, Douglas F. and Antoniou, Antonis C. (2010). Incorporating tumour pathology information into breast cancer risk prediction algorithms. Breast Cancer Research, 12 (3) R28, R28 - 1-R28 - 12. doi: 10.1186/bcr2576

  • Pathology of hereditary breast cancer

    Da Silva, Leonard and Lakhani, Sunil R. (2010). Pathology of hereditary breast cancer. Modern Pathology, 23 (S2), S46-S51. doi: 10.1038/modpathol.2010.37

  • DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status

    Flanagan, James M., Cocciardi, Sibylle, Waddell, Nic, Johnstone, Cameron N., Marsh, Anna, Henderson, Stephen, Simpson, Peter, da Silva, Leonard, kConFab Investigators, Khanna, Kumkum, Lakhani, Sunil, Boshoff, Chris, Chenevix-Trench, Georgia, Brown, Melissa, Cummings, Margaret and Edwards, Stacey (2010). DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status. American Journal of Human Genetics, 86 (3), 420-433. doi: 10.1016/j.ajhg.2010.02.008

  • Bayes analysis provides evidence of pathogenicity for the BRCA1 c.135-1G>T (IVS3-1) and BRCA2 c.7977-1G>C (IVS17-1) variants displaying in vitro splicing results of equivocal clinical significance.

    Spurdle, Amanda B., Lakhani, Sunil R., Da Silva, Leonard M., Balleine, Rosemary L., kConFab Investigators and Goldgar, David E. (2010). Bayes analysis provides evidence of pathogenicity for the BRCA1 c.135-1G>T (IVS3-1) and BRCA2 c.7977-1G>C (IVS17-1) variants displaying in vitro splicing results of equivocal clinical significance.. Human Mutation, 31 (2), E1141-E1145. doi: 10.1002/humu.21181

  • Breast pathology: Beyond morphology

    Simpson, Peter T., Reis-Filho, Jorge S. and Lakhani, Sunil R. (2010). Breast pathology: Beyond morphology. Seminars in Diagnostic Pathology, 27 (1), 91-96. doi: 10.1053/j.semdp.2009.12.001

  • Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?

    Lakhani, Sunil R., Khanna, Kum K. and Chenevix-Trench, Georgia (2010). Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?. Breast Cancer Research, 12 (2) 104, 104-1-104-2. doi: 10.1186/bcr2483

  • Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study

    Milne, Roger L., Gaudet, Mia M., Spurdle, Amanda B., Fasching, Peter A., Couch, Fergus J., Benitez, Javier, Arias Perez, Jose Ignacio, Zamora, M. Pilar, Malats, Nuria, dos Santos Silva, Isabel, Gibson, Lorna J., Fletcher, Olivia, Johnson, Nichola, Anton-Culver, Hoda, Ziogas, Argyrios, Figueroa, Jonine, Brinton, Louise, Sherman, Mark E., Lissowska, Jolanta, Hopper, John L., Dite, Gillian S., Apicella, Carmel, Southey, Melissa C., Sigurdson, Alice J., Linet, Martha S., Schonfeld, Sara J., Freedman, D. Michal, Mannermaa, Arto, Kosma, Veli-Matti ... Lakhani, Sunil (2010). Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study. Breast Cancer Research, 12 (6) R110, R110.1-R110.11. doi: 10.1186/bcr2797

  • Breast cancer prognostic classification in the molecular era: The role of histological grade

    Rakha, Emad A., Reis-Filho, Jorge S., Baehner, Frederick, Dabbs, David J., Decker, Thomas, Eusebi, Vincenzo, Fox, Stephen B., Ichihara, Shu, Jacquemier, Jocelyne, Lakhani, Sunil R., Palacios, José, Richardson, Andrea L., Schnitt, Stuart J., Schmitt, Fernando C., Tan, Puay-Hoon, Tse, Gary M., Badve, Sunil and Ellis, Ian (2010). Breast cancer prognostic classification in the molecular era: The role of histological grade. Breast Cancer Research, 12 (4) 207, 1-12. doi: 10.1186/bcr2607

  • HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer

    Da Silva, Leonard, Simpson, Peter T., Smart, Chanek E., Cocciardi, Sibylle, Waddell, Nic, Lane, Annette, Morrison, Brian J., Vargas, Ana Cristina, Healey, Sue, Beesley, Jonathan, Pakkiri, Pria, Parry, Suzanne, Kurniawan, Nyoman, Reid, Lynne, Keith, Patricia, Faria, Paulo, Pereira, Emilio, Skalova, Alena, Bilous, Michael, Balleine, Rosemary L., Do, Hongdo, Dobrovic, Alexander, Fox, Stephen, Franco, Marcello, Reynolds, Brent, Khanna, Kum Kum, Cummings, Margaret, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2010). HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer. Breast Cancer Research, 12 (4) R46, R46-1-R46-11. doi: 10.1186/bcr2603

  • CT-X antigen expression in human breast cancer

    Grigoriadis, Anita, Caballero, Otavia L., Hoek, Keith S., da Silva, Leonard, Chen, Yao-Tseng, Shin, Sandra J., Jungbluth, Achim A., Miller, Lance D., Clouston, David, Cebon, Jonathan, Old, Lloyd J., Lakhani, Sunil R., Simpson, Andrew J.G. and Neville, A. Munro Neville (2009). CT-X antigen expression in human breast cancer. Proceedings of the National Academy of Sciences, 106 (32), 13493-13498. doi: 10.1073/pnas.0906840106

  • Cancers in BRCA1 and BRCA2 carriers and in women at high risk for breast cancer: MR imaging and mammographic features

    Gilbert, Fiona J., Warren, Ruth M. L., Kwan-Lim, Gek, Thompson, Deborah J., Eeles, Ros A., Evans, D. Gareth, Leach, Martin O., United Kingdom Magnetic Resonance Imaging in Breast Screening (MARIBS) Study Group and Lakhani, S. R. (2009). Cancers in BRCA1 and BRCA2 carriers and in women at high risk for breast cancer: MR imaging and mammographic features. Radiology, 252 (2), 358-368. doi: 10.1148/radiol.2522081032

  • Fibroadenoma and intraduct papilloma--a common pathogenesis?

    Cummings, Margaret C., Da Silva, Leonard, Papadimos, David J. and Lakhani, Sunil R. (2009). Fibroadenoma and intraduct papilloma--a common pathogenesis?. Virchows Archiv, 455 (3), 271-275. doi: 10.1007/s00428-009-0817-8

  • Molecular evidence for progression of microglandular adenosis (MGA) to invasive carcinoma

    Shin, Sandra J., Simpson, Peter T., Da Silva, Leonard, Jayanthan, Janani, Reid, Lynne, Lakhani, Sunil R. and Rosen, Paul Peter (2009). Molecular evidence for progression of microglandular adenosis (MGA) to invasive carcinoma. The American Journal of Surgical Pathology, 33 (4), 496-504. doi: 10.1097/PAS.0b013e31818af361

  • Pleomorphic Lobular Carcinoma of the Breast: molecular pathology and clinical impact

    Vargas, Ana-Cristina, Lakhani‌, Sunil R. and Simpson, Peter T. (2009). Pleomorphic Lobular Carcinoma of the Breast: molecular pathology and clinical impact. Future Oncology, 5 (2), 233-243. doi: 10.2217/14796694.5.2.233

  • Current and future approach to the pathologist's assessment for targeted therapy in breast cancer

    Pakkiri, P, Lakhani, SR and Smart, CE (2009). Current and future approach to the pathologist's assessment for targeted therapy in breast cancer. Pathology, 41 (1), 89-99. doi: 10.1080/00313020802563551

  • Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis

    Da Silva, Leonard, Buck, Lyndall, Simpson, Peter T., Reid, Lynne, McCallum, Naomi, Madigan, Barry J. and Lakhani, Sunil R. (2009). Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis. Virchows Archiv, 454 (1), 107-114. doi: 10.1007/s00428-008-0700-z

  • Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

    Smart, Chanel E., Clarke, Catherine, Brooks, Kelly M., Raghavendra, Ashwini, Brewster, Brooke L., French, Juliet D., Hetherington, Rehan, Fleming, Jean S., Rothnagel, Joseph A., Wainwright, Brandon, Lakhani, Sunil R. and Brown, Melissa A. (2008). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. Breast Cancer Research and Treatment, 112 (2), 237-241. doi: 10.1007/s10549-007-9859-2

  • Breast cancer special types: why bother?

    Reis-Filho, J.S. and Lakhani, S.R. (2008). Breast cancer special types: why bother?. Journal of Pathology, 216 (4), 394-398. doi: 10.1002/path.2419

  • Breast cancer stem cells: Implications for therapy of breast cancer

    Morrison, Brian J., Schmidt, Chis W., Lakhani, Sunil, Reynolds, Brent A. and Alejandro, Lopez J. (2008). Breast cancer stem cells: Implications for therapy of breast cancer. Breast Cancer Research, 10 (4) 210, 210-1-210-14. doi: 10.1186/bcr2111

  • Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas

    Simpson, P. T., Reis-Filho, J. S., Lambros, M. B. K., Jones, C., Steele, D., Mackay, A., Iravani, M., Fenwick, K., Dexter, T., Jones, A., Reid, L., Da Silva, L., Shin, S. J., Hardisson, D., Ashworth, A., Schmitt, F. C., Palacios, J. and Lakhani, S.R. (2008). Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas. Journal of Pathology, 215 (3), 231-244. doi: 10.1002/path.2358

  • Aberrant expression of E-cadherin in lobular carcinomas of the breast

    DA Silva, L, Parry, S, Reid, L, Keith, P, Waddell, N, Kossai, M, Clarke, C, Lakhani, SR and Simpson, PT (2008). Aberrant expression of E-cadherin in lobular carcinomas of the breast. American Journal of Surgical Pathology, 32 (5), 773-783. doi: 10.1097/PAS.0b013e318158d6c5

  • Clinical classification of BRCA1 and BRCA2 DNA sequence variants: The value of cytokeratin profiles and evolutionary analysis - A report from the kConFab Investigators

    Spurdle, A.B., Lakhani, S.R., Healey, S., Parry, S., Da Silva, L. M., Brinkworth, R.I., Hopper, J.L., Brown, M.A., Babikyan, D., Chenevix-Trench, G., Tavtigian, S.V. and Goldgar, D.E. (2008). Clinical classification of BRCA1 and BRCA2 DNA sequence variants: The value of cytokeratin profiles and evolutionary analysis - A report from the kConFab Investigators. Journal of Clinical Oncology, 26 (10), 1657-1663. doi: 10.1200/JCO.2007.13.2779

  • Pathology in education and practice: a time for integration?

    Mortimer, R. and Lakhani, S. (2008). Pathology in education and practice: a time for integration?. Australian Health Review, 32 (2), 319-321. doi: 10.1071/AH080319

  • What's in a cancer syndrome? Genes, phenotype and pathology

    Wayte, Nicola, Da Silva, Leonard, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2008). What's in a cancer syndrome? Genes, phenotype and pathology. Pathology, 40 (3), 247-259. doi: 10.1080/00313020801911553

  • Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants?

    Lovelock, Paul K., Spurdle, Amanda B., Mok, Myth T. S., Farrugia, Daniel J., Lakhani, Sunil R., Healey, Sue, Arnold, Stephen, Buchanan, Daniel, kConFab Investigators, Couch, Fergus J., Henderson, Berik R., Goldgar, David E., Tavtigian, Sean V., Chenevix-Trench, Georgia and Brown, Melissa A (2007). Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants?. Breast Cancer Research, 9 (6: R82) R82, 1-13. doi: 10.1186/bcr1826

  • Mutation analysis of five candidate genes in familial breast cancer

    Marsh, Anna, Healey, Sue, Lewis, Aaron, Spurdle, Amanda B., Kedda, Mary Anne, Khanna, Kum Kum, Mann, Graham J., Pupo, Gulietta M., Lakhani, Sunil R. and Chenevix-Trench, Georgia (2007). Mutation analysis of five candidate genes in familial breast cancer. Breast Cancer Research & Treatment, 105 (3), 377-389. doi: 10.1007/s10549-006-9461-z

  • Genome-wide association study identifies novel breast cancer susceptibility loci

    Easton, Douglas F., Pooley, Karen A., Dunning, Alison M., Pharoah, Paul D. P., Thompson, Deborah, Ballinger, Dennis G., Struewing, Jeffery P., Morrison, Jonathan, Field, Helen, Luben, Robert, Wareham, Nicholas, Ahmed, Shahana, Healey, Catherine S., Bowman, Richard, SEARCH collaborators, Meyer, Kerstin B., Haiman, Christopher A., Kolonel, Laurence K., Henderson, Brian E., Marchand, Loic Le, Brennan, Paul, Sangrajrang, Suleeporn, Gaborieau, Valerie, Odefrey, Fabrice, Shen, Chen-Yang, Wu, Pei-Ei, Wang, Hui-Chun, Eccles Diana, Evans, D. Gareth ... Ward, Robyn (2007). Genome-wide association study identifies novel breast cancer susceptibility loci. Nature, 447 (7148), 1087-1093. doi: 10.1038/nature05887

  • Demystifying basal-like breast carcinomas

    Da Silva, L., Clarke, C. and Lakhani, S.R. (2007). Demystifying basal-like breast carcinomas. Journal of Clinical Pathology, 60 (12), 1328-1332. doi: 10.1136/jcp.2006.041731

  • Comparative molecular pathology of adenoid cystic carcinoma from different sites: A microarray-based CGH analysi

    Fulford, L. G., Reis, J. S., Mackay, A., Fenwick, K., Iravani, M., Ashworth, A., Nicholson, A. G., Schmitt, F. C., Simpson, H. W. and Lakhani, S. R. (2007). Comparative molecular pathology of adenoid cystic carcinoma from different sites: A microarray-based CGH analysi. Laboratory Investigation, 87 (Supplement 1s), 305A-306A. doi: 10.1038/sj.labinvest.3700582

  • Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival

    Fulford, Laura G., Reis-Filho, Jorge S., Ryder, Ken, Jones, Chris, Gillett, Cheryl E., Hanby, Andrew, Easton, Douglas and Lakhani, Sunil R. (2007). Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival. Breast Cancer Research, 9 (1) R4, 1-11. doi: 10.1186/bcr1636

  • Comparative molecular pathology of adenoid cystic carcinoma from different sites: A microarray-based CGH analysis

    Fulford, L. G., Reis, J. S., Mackay, A., Feinwick, K., Iravani, M., Ashworth, A., Nicholson, A. G., Schmitt, F. C., Simpson, R. H. W. and Lakhani, Sunil R. (2007). Comparative molecular pathology of adenoid cystic carcinoma from different sites: A microarray-based CGH analysis. Modern Pathology, 20 (Supplement 2s), 305A-306A. doi: 10.1038/sj.modpathol.3800815

  • In situ carcinoma - can we predict which patient will come back with a recurrence?

    Simpson, P.T., Da Silva, L. M and Lakhani, S.R. (2007). In situ carcinoma - can we predict which patient will come back with a recurrence?. Cancer Cell, 12 (5), 409-411. doi: 10.1016/j.ccr.2007.10.026

  • FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas

    Reis-Filho, Jorge Sergio, Simpson, Pete T., Turner, Nicholas C., Lambros, Maryou Ballo, Jones, Chris, Mackay, Alan, Grigoriadis, Anita, Sarrio, David, Savage, Kay, Dexter, Tim, Iravani, Marjan, Fenwick, Kerry, Weber, Barbara, Hardisson, David, Schmitt, Fernando Carlos, Palacios, Jose, Lakhani, Sunil R. and Ashworth, Alan (2006). FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas. Clinical Cancer Research, 12 (22), 6652-6662. doi: 10.1158/1078-0432.CCR-06-1164

  • Genetic and Histopathologic Evaluation of BRCA1 and BRCA2 DNA Sequence Variance of Unknown Clinical Significance

    Chenevix-Trench, Georgia, Healey, Sue, Lakhani, Sunil, Waring, Paul, Cummings, Margaret, Brinkworth, Ross, Deffenbaugh, Amie M., Burbidge, Lynn Anne, Pruss, Dmitry, Judkins, Thad, Scholl, Tom, Bekessy, Anna, Marsh, Anna, Lovelock, Paul, Wong, Ming, Tesoriero, Andrea, Renard, Helene, Southey, Melissa, Hopper, John L., Yannoukakos, Koulis, Brown, Melissa, kConFab Investigators, Easton, Douglas, Tavtigian, Sean V., Goldgar, David and Spurdle, Amanda B. (2006). Genetic and Histopathologic Evaluation of BRCA1 and BRCA2 DNA Sequence Variance of Unknown Clinical Significance. Cancer Research, 66 (4), 2019-2027. doi: 10.1158/0008-5472.CAN-05-3546

  • A Test of Performance of Breast MRI Interpretation in a Multicentre Screening Study

    Warren, Ruth, Hayes, Carmel, Pointon, Linda, Hoff, Rebecca, Gilbert, Fiona J., Padhani, Anwar R., Rubin, Caroline, Kaplan, Glenda, Raza, Kauza, Wilkinson, Laura, Hall-Craggs, Margaret, Kessar, Preminda, Rankin, Sheila, Dixon, Adrian K., Walsh, James, Turnbull, Lindsay, Britton, Peter, Sinnatamby, Ruchi, Easton, Doug, Thompson, Deborah, Lakhani, Sunil R., Leach, Martin O. and MARIBS (2006). A Test of Performance of Breast MRI Interpretation in a Multicentre Screening Study. Magnetic Resonance Imaging, 24 (7), 917-929. doi: 10.1016/j.mri.2006.03.004

  • Basal-like breast carcinomas: clinical outcome and response to chemotherapy

    Banerjee, S., Reis, J. S., Ashley, S., Steele, D., Ashworth, A., Lakhani, S. R. and Smith, I. E. (2006). Basal-like breast carcinomas: clinical outcome and response to chemotherapy. Journal of Clinical Pathology, 59 (7), 729-735. doi: 10.1136/jcp.2005.033043

  • Cost-effectiveness of screening with contrast enhanced magnetic resonance imaging vs X-ray mammography of women at a high familial risk of breast cancer

    Griebsch, I., Brown, J., Boggis, C., Dixon, A., Dixon, M., Easton, D., Eeles, R., Evans, D. G., Gilbert, F. J., Hawnaur, J., Kessar, P., Lakhani, S. R., Moss, S. M., Nerurkar, A. and Padhani, A. R. (2006). Cost-effectiveness of screening with contrast enhanced magnetic resonance imaging vs X-ray mammography of women at a high familial risk of breast cancer. British Journal of Cancer, 95 (7), 801-810. doi: 10.1038/sj.bjc.6603356

  • EGFR amplification and lack of activating mutations in metaplastic breast carcinomas

    Reis-Filho, J. S., Pinheiro, C., Lambros, M. B. K., Milanezi, F., Carvalho, S., Savage, K., Simpson, P. T., Jones, C., Swift, S., Mackay, A., Reis, R. M., Hornick, J. L., Pereira, E. M., Baltazar, F., Fletcher, C. D. M., Ashworth, A., Lakhani, S. R. and Schmitt, F. C. (2006). EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. Journal of Pathology, 209 (4), 445-453. doi: 10.1002/path.2004

  • EGFR expression predicts BRCA1 status in patients with breast cancer - In response

    Lakhani, S. R. (2006). EGFR expression predicts BRCA1 status in patients with breast cancer - In response. Clinical Cancer Research, 12 (2), 671-671. doi: 10.1158/1078-0432.CCR-05-2297

  • Evaluation of a prospective scoring system designed for a multicenter breast MR imaging screening study

    Warren, RML, Thompson, D, Pointon, LJ, Hoff, R, Gilbert, FJ, Padhani, AR, Easton, DF, Lakhani, SR and Leach, MO (2006). Evaluation of a prospective scoring system designed for a multicenter breast MR imaging screening study. Radiology, 239 (3), 677-685. doi: 10.1148/radiol.2393042007

  • Expression profiling using cDNA microarrays

    Jones, Chris, Simpson, Peter, Mackay, Alan and Lakhani, Sunil R (2006). Expression profiling using cDNA microarrays. Methods in molecular medicine, 120, 403-414.

  • Gene expression analysis using filter cDNA microarrays

    Simpson, Peter, Jones, Chris, Mackay, Alan and Lakhani, Sunil R (2006). Gene expression analysis using filter cDNA microarrays. Methods in molecular medicine, 120, 415-424.

  • Introduction: The role of myoepithelial cells in integration of form and function in the mammary gland

    Lakhani, S. and Bissell, M. (2006). Introduction: The role of myoepithelial cells in integration of form and function in the mammary gland. Journal of Mammary Gland Biology & Neoplasia, 10 (3), 197-198. doi: 10.1007/s10911-005-9580-x

  • Mapping loss of heterozygosity in normal human breast cells from BRCA1/2 carriers

    Clarke, C. L., Sandle, J., Jones, A. A., Sofronis, A., Patani, N. R. and Lakhani, S. R. (2006). Mapping loss of heterozygosity in normal human breast cells from BRCA1/2 carriers. British Journal of Cancer, 95 (4), 515-519. doi: 10.1038/sj.bjc.6603298

  • Metaplastic breast carcinomas are basal-like tumours

    Reis-Filho, J. S., Milanezi, F., Steele, D., Savage, K., Simpson, P. T., Nesland, J. M., Pereira, E. M., Lakhani, S. R. and Schmitt, F. C. (2006). Metaplastic breast carcinomas are basal-like tumours. Histopathology, 49 (1), 10-21. doi: 10.1111/j.1365-2559.2006.02467.x

  • Pathological complete response and residual DCIS following neoadjuvant chemotherapy for breast carcinoma

    Jones, R. L., Lakhani, S. R., Ring, A. E., Ashley, S., Walsh, G. and Smith, I. E. (2006). Pathological complete response and residual DCIS following neoadjuvant chemotherapy for breast carcinoma. British Journal of Cancer, 94 (3), 358-362. doi: 10.1038/sj.bjc.6602950

  • Reply to the letter to the editor by Van Diest, et al

    Lakhani, Sunil R. (2006). Reply to the letter to the editor by Van Diest, et al. Clinical Cancer Research, 12 (2), 671-671. doi: 10.1158/1078-0432.CCR-05-2297

  • Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast

    Fulford, L. G., Easton, D. F., Reis-Filho, J. S., Sofronis, A., Gillett, C. E., Lakhani, S. R. and Hanby, A. (2006). Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast. Histopathology, 49 (1), 22-34. doi: 10.1111/j.1365-2559.2006.02453.x

  • The management of lobular carcinoma in situ (LCIS). Is LCIS the same as ductal carcinoma in situ (DCIS)?

    Lakhani, SR, Audretsch, W, Cleton-Jensen, AM, Cutuli, B, Ellis, I, Eusebi, V, Greco, M, Houslton, RS, Kuhl, CK, Kurtz, J, Palacios, J, Peterse, H, Rochard, F and Rutgers, E (2006). The management of lobular carcinoma in situ (LCIS). Is LCIS the same as ductal carcinoma in situ (DCIS)?. European Journal of Cancer, 42 (14), 2205-2211. doi: 10.1016/j.ejca.2006.03.019

  • The molecular genetics of breast cancer: The contribution of comparative genomic hybridization

    Reis-Filho, Jorge S., Simpson, Peter T., Gale, Theodora and Lakhani, Sunil R. (2005). The molecular genetics of breast cancer: The contribution of comparative genomic hybridization. Pathology Research & Practice, 201 (11), 713-725. doi: 10.1016/j.prp.2005.05.013

  • Myoepithelial calls: Pathology, cell separation and markers of myoepithelial differentiation

    Clarke, Catherine, Sandle, Jennifer and Lakhani, Sunil R. (2005). Myoepithelial calls: Pathology, cell separation and markers of myoepithelial differentiation. Journal of Mammary Gland Biology and Neoplasia, 10 (3), 273-280. doi: 10.1007/s10911-005-9587-3

  • A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer

    Stephens, P., Edkins, S., Davies, H., Greenman, C., Cox, C., Hunter, C., Bignell, G., Teague, J., Smith, R., Stevens, C., O'Meara, S., Parker, A., Tarpey, P., Avis, T., Barthorpe, A., Brackenbury, L., Buck, G., Butler, A., Clements, J., Cole, J., Dicks, E., Edwards, K., Forbes, S., Gorton, M., Gray, K., Halliday, K., Harrison, R., Hills, K., Hinton, J. ... Wooster, R. (2005). A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer. Nature Genetics, 37 (6), 590-592. doi: 10.1038/ng1571

  • Columnar cell lesions of the breast: The missing link in breast cancer progression? A morphological and molecular analysis

    Simpson, P. T., Gale, T., Reis-Filho, J. S., Jones, C., Parry, S., Sloane, J. P., Hanby, A., Pinder, S. E., Lee, A. H. S., Humphreys, S., Ellis, I. O. and Lakhani, S. R. (2005). Columnar cell lesions of the breast: The missing link in breast cancer progression? A morphological and molecular analysis. American Journal of Surgical Pathology, 29 (6), 734-746. doi: 10.1097/01.pas.0000157295.93914.3b

  • Phase I pharmacokinetic and pharmacodynarnic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies

    Banerji, Udai, O'Donnell, Anne, Scurr, Michelle, Pacey, Simon, Stapleton, Sarah, Asad, Yasmin, Simmons, Laura, Maloney, Alison, Raynaud, Florence, Campbell, Maeli, Walton, Micheal, Lakhani, Sunil, Kaye, Stanley, Workman, Paul and Judson, Ian (2005). Phase I pharmacokinetic and pharmacodynarnic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies. Journal of Clinical Oncology, 23 (18), 4152-4161. doi: 10.1200/JCO.2005.00.612

  • Continued axillary sampling is unnecessary and provides no further information to sentinel node biopsy in staging breast cancer

    Gui, GPH, Joubert, DJ, Reichert, R, Ward, A, Lakhani, S, Osin, P, Nerurkar, A, A'Hern, R, Benson, K and Underwood, SR (2005). Continued axillary sampling is unnecessary and provides no further information to sentinel node biopsy in staging breast cancer. Ejso, 31 (7), 707-714. doi: 10.1016/j.ejso.2005.04.014

  • Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: Immunohistochemical and chromogenic in situ hybridization analysis

    Reis-Filho, Jorge S., Milanezi, Fernanda, Carvalho, Silvia, Simpson, Peter T., Steele, Dawn, Savage, Kay, Lambros, Maryou B. K., Pereira, Emilio M., Nesland, John M., Lakhani, Sunil R. and Schmitt, Fernando C. (2005). Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: Immunohistochemical and chromogenic in situ hybridization analysis. Breast Cancer Research, 7 (6) R1028, R1028-R1035. doi: 10.1186/bcr1341

  • Molecular evolution of breast cancer

    Simpson, P. T., Reis-Filho, J. S., Gale, T. and Lakhani, S. R. (2005). Molecular evolution of breast cancer. Journal of Pathology, 205 (2), 248-254. doi: 10.1002/path.1691

  • Pleomorphic lobular carcinoma of the breast: role of comprehensive molecular pathology in characterization of an entity

    Reis-Filho, J. S., Simpson, P. T., Jones, C., Steele, D., Mackay, A., Iravani, M., Fenwick, K., Valgeirrson, H., Lambros, M., Ashworth, A., Palacios, J., Schmitt, F. and Lakhani, S. R. (2005). Pleomorphic lobular carcinoma of the breast: role of comprehensive molecular pathology in characterization of an entity. Journal of Pathology, 207 (1), 1-13. doi: 10.1002/path.1806

  • Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype

    Lakhani, S. R., Reis-Filho, J. S., Fulford, L., Penault-Llorca, F., van der Vjiver, M., Parry, S., Bishop, T., Benitez, J., Rivas, C., Bignon, Y. J., Chang-Claude, J., Hamann, U., Cornelisse, C. J., Devilee, P. and Beckmann, M. W. (2005). Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype. Clinical Cancer Research, 11 (14), 5175-5180. doi: 10.1158/1078-0432.CCR-04-2424

  • Reading protocol for dynamic contrast-enhanced MR images of the breast: Sensitivity and specificity analysis

    Warren, RML, Pointon, L, Thompson, D, Hoff, R, Gilbert, FJ, Padhani, A, Easton, D, Lakhani, SR and Leach, MO (2005). Reading protocol for dynamic contrast-enhanced MR images of the breast: Sensitivity and specificity analysis. Radiology, 236 (3), 779-788. doi: 10.1148/radiol.2363040735

  • Screening with magnetic resonance imaging and mammography of a UK population at high familial risk of breast cancer: a prospective multicentre cohort study (MARIBS)

    Leach, M. O., Boggis, C. R. M., Dixon, A. K., Easton, D. F., Eeles, R. A., Evans, D. G. R., Gilbert, F. J., Griebsch, I., Hoff, R. J. C., Kessar, P., Lakhani, S. R. and Moss, S. M. (2005). Screening with magnetic resonance imaging and mammography of a UK population at high familial risk of breast cancer: a prospective multicentre cohort study (MARIBS). The Lancet, 365 (9473), 1769-1778. doi: 10.1016/S0140-6736(05)66481-1

  • Somatic mutations of the protein kinase gene family in human lung cancer

    Davies, H, Hunter, C, Smith, R, Stephens, P, Greenman, C, Bignell, G, Teague, B, Butler, A, Edkins, S, Stevens, C, Parker, A, O'Meara, S, Avis, T, Barthorpe, S, Brackenbury, L, Buck, G, Clements, B, Cole, J, Dicks, E, Edwards, K, Forbes, S, Gorton, M, Gray, K, Halliday, K, Harrison, R, Hills, K, Hinton, J, Jones, D, Kosmidou, V ... Futreal, PA (2005). Somatic mutations of the protein kinase gene family in human lung cancer. Cancer Research, 65 (17), 7591-7595. doi: 10.1158/0008-5472.CAN-05-1855

  • Typical medullary breast carcinomas have a basal/myoepithelial phenotype

    Jacquemier, J., Padovani, L., Rabayrol, L., Lakhani, S. R., Penault-Llorca, F., Denoux, Y., Fiche, M., Figueiro, P., Maisongrosse, V., Ledoussal, V., Penuela, J. M., Udvarhely, N., El Makdissi, G., Ginestier, C. and Geneix, J. (2005). Typical medullary breast carcinomas have a basal/myoepithelial phenotype. Journal of Pathology, 207 (3), 260-268. doi: 10.1002/path.1845

  • Molecular cytogenetic identification of subgroups of grade III invasive ductal breast carcinomas with different clinical outcomes

    Jones, Chris, Ford, Emily, Gillett, Cheryl, Ryder, Ken, Merrett, Samantha, Reis, Jorge S., Fulford, Laura G., Hanby, Andrew and Lakhani, Sunil R. (2004). Molecular cytogenetic identification of subgroups of grade III invasive ductal breast carcinomas with different clinical outcomes. Clinical Cancer Research, 10 (18), 5988-5997. doi: 10.1158/1078-0432.CCR-03-0731

  • Expression profiling of purified normal human luminal and myoepithelial breast cells: Identification of novel prognostic markers for breast cancer

    Jones, Chris, Mackay, Alan, Grigoriadis, Anita, Cossu, Antonio, Reis-Filho, Jorge S., Fulford, Laura, Dexter, Tim, Davies, Susan, Bulmer, Karen, Ford, Emily, Parry, Suzanne, Budroni, Mario, Palmieri, Giuseppe, Neville, A. Munro, O'Hare, Michael J. and Lakhani, Sunil R. (2004). Expression profiling of purified normal human luminal and myoepithelial breast cells: Identification of novel prognostic markers for breast cancer. Cancer Research, 64 (9), 3037-3045. doi: 10.1158/0008-5472.CAN-03-2028

  • Putting the brakes on cylindromatosis?

    Lakhani, Sunil R. (2004). Putting the brakes on cylindromatosis?. New England Journal of Medicine, 350 (2), 187-188. doi: 10.1056/NEJMcibr032650

  • Collagenous spherulosis in an adenomyoepithelioma of the breast

    Reis-Filho, J. S., Fulford, L. G., Crebassa, B., Carpentier, S. and Lakhani, S. R. (2004). Collagenous spherulosis in an adenomyoepithelioma of the breast. Journal of Clinical Pathology, 57 (1), 83-86. doi: 10.1136/jcp.57.1.83

  • Cytokeratin 5/6 in normal human breast: lack of evidence for a stem cell phenotype

    Clarke, CL, Sandle, J, Parry, SC, Reis, JS, O'Hare, MJ and Lakhani, SR (2004). Cytokeratin 5/6 in normal human breast: lack of evidence for a stem cell phenotype. Journal of Pathology, 204 (2), 147-152. doi: 10.1002/path.1647

  • Distribution and significance of 14-3-3 sigma, a novel myoepithelial marker, in normal, benign, and malignant breast tissue

    Simpson, Peter T., Gale, Theodora, Reis-Filho, Jorge S, Jones, Chris, Parry, Suzanne, Steele, Dawn, Cossu, Antonio, Budroni, Mario, Palmieri, Giuseppe and Lakhani, Sunil R (2004). Distribution and significance of 14-3-3 sigma, a novel myoepithelial marker, in normal, benign, and malignant breast tissue. Journal of Pathology, 202 (3), 274-285. doi: 10.1002/path.1530

  • Expression of ATM, p53, and the MRE11-Rad50-NBS1 complex in myoepithelial cells from benign and malignant proliferations of the breast

    Angele, S., Jones, C., Reis Filho, J. S., Fulford, L. G., Treilleux, I. and Lakhani, S. R. (2004). Expression of ATM, p53, and the MRE11-Rad50-NBS1 complex in myoepithelial cells from benign and malignant proliferations of the breast. Journal of Clinical Pathology, 57 (11), 1179-1184. doi: 10.1136/jcp.2004.017434

  • Grade of recurrent in situ and invasive carcinoma following treatment of pure ductal carcinoma in situ of the breast

    Millis, R. R., Pinder, S. E., Ryder, K., Howitt, R. and Lakhani, S. R. (2004). Grade of recurrent in situ and invasive carcinoma following treatment of pure ductal carcinoma in situ of the breast. British Journal of Cancer, 90 (8), 1538-1542. doi: 10.1038/sj.bjc.6601704

  • Oestrogen receptor status, pathological complete response and prognosis in patients receiving neoadjuvant chemotherapy for early breast cancer

    Ring, A. E., Smith, I. E., Ashley, S., Fulford, L. G. and Lakhani, S. R. (2004). Oestrogen receptor status, pathological complete response and prognosis in patients receiving neoadjuvant chemotherapy for early breast cancer. British Journal of Cancer, 91 (12), 2012-2017. doi: 10.1038/sj.bjc.6602235

  • Pathology of ovarian cancers in BRCA1 and BRCA2 carriers

    Lakhani, SR, Manek, S, Penault-Llorca, F, Flanagan, A, Arnout, L, Merrett, S, McGuffog, L, Steele, D, Devilee, P, Klijn, JGM, Meijers-Heijboer, H, Radice, P, Pilotti, S, Nevanlinna, H, Butzow, R, Sobol, H, Jacquemier, J, Lyonet, DS, Neuhausen, SL, Weber, B, Wagner, T, Winqvist, R, Bignon, YJ, Monti, F, Schmitt, F, Lenoir, G, Seitz, S, Hamman, U, Pharoah, P ... Easton, DF (2004). Pathology of ovarian cancers in BRCA1 and BRCA2 carriers. Clinical Cancer Research, 10 (7), 2473-2481. doi: 10.1158/1078-0432.CCR-1029-3

  • The diagnosis and management of pre-invasive breast disease: Editor's reply

    Lakhani, Sunil R. (2004). The diagnosis and management of pre-invasive breast disease: Editor's reply. Breast Cancer Research, 6 (1: E4), 1-2. doi: 10.1186/bcr741

  • The inframammary fold: contents, clinical significance and implications for immediate breast reconstruction

    Gui, GPH, Behranwala, KA, Abdullah, N, Seet, J, Osin, P, Nerurkar, A and Lakhani, SR (2004). The inframammary fold: contents, clinical significance and implications for immediate breast reconstruction. British Journal of Plastic Surgery, 57 (2), 146-149. doi: 10.1016/j.bjps.2003.11.030

  • Pathologic quiz case: A 93-year-old woman with an enlarged and tender left breast

    Reis-Filho, Jorge S., Fulford, Laura G., Freeman, Alex and Lakhani, Sunil R. (2003). Pathologic quiz case: A 93-year-old woman with an enlarged and tender left breast. Archives of Pathology & Laboratory Medicine, 127 (12), 1626-1628.

  • The diagnosis and management of pre-invasive breast disease: Editor's reply

    Lakhani, Sunil R. (2003). The diagnosis and management of pre-invasive breast disease: Editor's reply. Breast Cancer Research, 6 (1), E4.1-E4.2. doi: 10.1186/bcr741

  • A 62-year-old woman with a 4.5-cm nodule in the right breast

    Reis-Filho, Jorge S., Fulford, Laura G., Lakhani, Sunil R. and Schmitt, Fernando C. (2003). A 62-year-old woman with a 4.5-cm nodule in the right breast. Archives of Pathology and Laboratory Medicine, 127 (9), e396-e398.

  • The morphology of breast tumors in BRCA1/2 carriers

    Lakhani, Sunil R. (2003). The morphology of breast tumors in BRCA1/2 carriers. Pathology Case Reviews, 8 (5), 240-244.

  • Malignant adenomyoepithelioma of the breast metastasizing to the liver [Letter to the Editor]

    Jones, Chris, Tooze, Reuben and Lakhani, Sunil R. (2003). Malignant adenomyoepithelioma of the breast metastasizing to the liver [Letter to the Editor]. Virchows Archiv, 442 (5), 504-506. doi: 10.1007/s00428-003-0806-2

  • Progesterone receptor-positive eruptive syringoma associated with diabetes

    Timpanidis, Penelope C., Lakhani, Sunil R. and Groves, Richard W. (2003). Progesterone receptor-positive eruptive syringoma associated with diabetes. Journal of The American Academy of Dermatology, 48 (5, Supp. 1), S103-S104. doi: 10.1067/mjd.2003.159

  • BCL-6 is expressed in breast cancer and prevents mammary epithelial differentiation

    Logarajah, S, Hunter, P, Kraman, M, Steele, D, Lakhani, S, Bobrow, L, Venkitaraman, A and Wagner, S (2003). BCL-6 is expressed in breast cancer and prevents mammary epithelial differentiation. Oncogene, 22 (36), 5572-5578. doi: 10.1038/sj.onc.1206689

  • Can the stroma provide the clue to the cellular basis for mammographic density?

    Warren, R and Lakhani, SR (2003). Can the stroma provide the clue to the cellular basis for mammographic density?. Breast Cancer Research, 5 (5), 225-227. doi: 10.1186/bcr642

  • Comparative genomic hybridization analysis of bilateral hyperplasia of usual type of the breast

    Jones, C, Merrett, S, Thomas, VA, Barker, TH and Lakhani, SR (2003). Comparative genomic hybridization analysis of bilateral hyperplasia of usual type of the breast. Journal of Pathology, 199 (2), 152-156. doi: 10.1002/path.1280

  • Genetic alterations in pre-invasive lesions

    Reis-Filho, Jorge S. and Lakhani, Sunil R. (2003). Genetic alterations in pre-invasive lesions. Breast Cancer Research, 5 (6) 313, 313-319. doi: 10.1186/bcr650

  • In-situ lobular neoplasia: time for an awakening

    Lakhani, Sunil R. (2003). In-situ lobular neoplasia: time for an awakening. The Lancet, 361 (9352), 96-96. doi: 10.1016/S0140-6736(03)12240-4

  • Pathology of atypical lobular hyperplasia and lobular carcinoma in situ

    Simpson, Peter T., Gale, Theodora, Fulford, Laura G., Reis-Filho, Jorge S. and Lakhani, Sunil R. (2003). Pathology of atypical lobular hyperplasia and lobular carcinoma in situ. Breast Cancer Research, 5 (5), 258-262. doi: 10.1186/bcr624

  • Salivary gland-like tumours of the breast: surgical and molecular pathology

    Pia-Foschini, M., Reis, J. S., Eusebi, V. and Lakhani, S. R. (2003). Salivary gland-like tumours of the breast: surgical and molecular pathology. Journal of Clinical Pathology, 56 (7), 497-506. doi: 10.1136/jcp.56.7.497

  • The diagnosis and management of pre-invasive breast disease — current challenges, future hopes

    Lakhani, Sunil R. (2003). The diagnosis and management of pre-invasive breast disease — current challenges, future hopes. Breast Cancer Research, 5 (5), 248-249. doi: 10.1186/bcr641

  • X-inactivation patch size in human female tissue confounds the assessment of tumor clonality

    Novelli, M, Cossu, A, Oukrif, D, Quaglia, A, Lakhani, S, Poulsom, R, Sasieni, P, Carta, P, Contini, M, Pasca, A, Palmieri, G, Bodmer, W, Tanda, F and Wright, N (2003). X-inactivation patch size in human female tissue confounds the assessment of tumor clonality. Proceedings of The National Academy of Sciences of The United States of America, 100 (6), 3311-3314. doi: 10.1073/pnas.0437825100

  • cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells

    Mackay, A., Jones, C., Dexter, T., Silva, R. L. A., Bulmer, K., Jones, A., Simpson, P., Harris, R. A., Jat, P. S., Neville, A. M., Reis, L. F. L., Lakhani, S. R. and O'Hare, M. J. (2003). cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells. Oncogene, 22 (17), 2680-2688. doi: 10.1038/sj.onc.1206349

  • The pathology of familial breast cancer: Predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2

    Lakhani, Sunil R., van de Vijver, Marc J., Jacquemier, Jocelyne, Anderson, Thomas J., Osin, Peter P., McGuffog, Lesley and Easton, Douglas F. (2002). The pathology of familial breast cancer: Predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2. Journal of Clinical Oncology, 20 (9), 2310-2318. doi: 10.1200/JCO.2002.09.023

  • The Significance of Early Breast Lesions

    Clarke, C. and Lakhani, S. R. (2002). The Significance of Early Breast Lesions. Breast Cancer Online, 5, 1-5.

  • The Wnt pathway, epithelial-stromal interactions, and malignant progression in phyllodes tumours

    Sawyer, EJ, Hanby, AM, Rowan, AJ, Gillett, CE, Thomas, RE, Poulsom, R, Lakhani, SR, Ellis, IO, Ellis, P and Tomlinson, IPM (2002). The Wnt pathway, epithelial-stromal interactions, and malignant progression in phyllodes tumours. Journal of Pathology, 196 (4), 437-444. doi: 10.1002/path.1067

  • The expression patterns of integrin subunits on human breast tissues obtained during pregnancy

    Suzuki, RN, Entwistle, A, Atherton, AJ, Clarke, C, Lakhani, SR and O'Hare, MJ (2002). The expression patterns of integrin subunits on human breast tissues obtained during pregnancy. Cell Biology International, 26 (7), 593-598. doi: 10.1006/cbir.2002.0880

  • Microarray and histopathological analysis of tumours: The future and the past?

    Lakhani, Sunil R. and Ashworth, Alan (2001). Microarray and histopathological analysis of tumours: The future and the past?. Nature Reviews Cancer, 1 (2), 151-157. doi: 10.1038/35101087

  • CGH analysis of ductal carcinoma of the breast with basaloid/myoepithelial cell differentiation

    Jones, C., Nonni, A. V., Fulford, L., Merrett, S., Chaggar, R., Eusebi, V. and Lakhani, S. R. (2001). CGH analysis of ductal carcinoma of the breast with basaloid/myoepithelial cell differentiation. British Journal of Cancer, 85 (3), 422-427. doi: 10.1054/bjoc.2001.1869

  • Profiling familial breast cancer

    Lakhani, SR, O'Hare, MJ and Ashworth, A (2001). Profiling familial breast cancer. Nature Medicine, 7 (4), 408-410. doi: 10.1038/86464

  • Profiling familial breast cancer

    Lakhani, Sunil R., O'Hare, Michael J. and Ashworth, Alan (2001). Profiling familial breast cancer. Nature Medicine, 7 (4), 408-410. doi: 10.1038/86464

  • Contribution of germline MLH1 and MSH2 mutations to lobular carcinoma in situ of the breast

    Stone, JG, Coleman, G, Gusterson, B, Marossy, A, Lakhani, SR, Ward, A, Nash, A, McKinna, A, A'Hern, R, Stratton, MR and Houlston, RS (2001). Contribution of germline MLH1 and MSH2 mutations to lobular carcinoma in situ of the breast. Cancer Letters, 167 (2), 171-174. doi: 10.1016/S0304-3835(01)00448-7

  • Loss of heterozygosity at cylindromatosis gene locus, CYLD, in sporadic skin adnexal tumours

    Leonard, N, Chaggar, R, Jones, C, Takahashi, M, Nikitopoulou, A and Lakhani, SR (2001). Loss of heterozygosity at cylindromatosis gene locus, CYLD, in sporadic skin adnexal tumours. Journal of Clinical Pathology, 54 (9), 689-692. doi: 10.1136/jcp.54.9.689

  • MR imaging of the skin and nipple of the breast: differentiation between tumour recurrence and post-treatment change

    Ralleigh, G, Walker, AE, Hall-Craggs, MA, Lakhani, SR and Saunders, C (2001). MR imaging of the skin and nipple of the breast: differentiation between tumour recurrence and post-treatment change. European Radiology, 11 (9), 1651-1658. doi: 10.1007/s003300100837

  • Molecular cytogenetic comparison of apocrine hyperplasia and apocrine carcinoma of the breast

    Jones, C, Damiani, S, Wells, D, Chaggar, R, Lakhani, SR and Eusebi, V (2001). Molecular cytogenetic comparison of apocrine hyperplasia and apocrine carcinoma of the breast. American Journal of Pathology, 158 (1), 207-214. doi: 10.1016/S0002-9440(10)63959-4

  • Molecular genetics of solid tumours: translating research into clinical practice. What we could do now: breast cancer

    Lakhani, SR (2001). Molecular genetics of solid tumours: translating research into clinical practice. What we could do now: breast cancer. Journal of Clinical Pathology-molecular Pathology, 54 (5), 281-284. doi: 10.1136/mp.54.5.281

  • The mammary myoepithelial cell - Cinderella or ugly sister?

    Lakhani, SR and O'Hare, MJ (2001). The mammary myoepithelial cell - Cinderella or ugly sister?. Breast Cancer Research, 3 (1) 1, 1-4. doi: 10.1186/bcr260

  • Proliferation and differentiation in the human breast during pregnancy

    Suzuki, R., Atherton, A. J., O'Hare, M. J., Entwistle, A., Lakhani, S. R. and Clarke, C. (2000). Proliferation and differentiation in the human breast during pregnancy. Differentiation, 66 (2-3), 106-115. doi: 10.1046/j.1432-0436.2000.660205.x

  • Clonality analysis of defined cell populations in paraffin-embedded tissue sections by RT-PCR amplification of X-linked G6PD gene

    Peng, Huaizheng, Lakhani, Sunil R., Lee, Chungyin, Zheng, Qiang, Chaggar, Ranbir K., Wright, Nicholas A., Pan, Langxing and Isaacson, Peter G. (2000). Clonality analysis of defined cell populations in paraffin-embedded tissue sections by RT-PCR amplification of X-linked G6PD gene. Journal of Pathology, 191 (3), 313-317. doi: 10.1002/1096-9896(2000)9999:9999<::AID-PATH621>3.0.CO;2-3

  • Comparative genomic hybridization analysis of myoepithelial carcinoma of the breast

    Jones, C., Foschini, M. P., Chaggar, R., Lu, Y. J., Wells, D., Shipley, J. M., Eusebi, V. and Lakhani, S. R. (2000). Comparative genomic hybridization analysis of myoepithelial carcinoma of the breast. Laboratory Investigation, 80 (6), 831-836. doi: 10.1038/labinvest.3780087

  • Identification of the familial cylindromatosis tumour-suppressor gene

    Bignell, Graham R., Warren, William, Seal, Sheila, Takahashi, Meiko, Rapley, Elizabeth, Barfoot, Rita, Green, Helen, Brown, Carolanne, Biggs, Patrick J., Lakhani, Sunil R., Jones, Christopher, Hansen, Juliana, Blair, Edward, Hofmann, Benedikt, Siebert, Reiner, Turner, Gwen, Evans, D. Gareth, Schrander-Stumpel, Connie, Beemer, Frits A., van den Ouweland, Ans, Halley, Dicky, Delpech, Bertrand, Cleveland, Mark G., Jaakko, Irene Leigh, Rasmussen, Leisti Sonja, Wallace, Margaret R., Fenske, Christiane, Banerjee, Piu, Oiso, Naoki ... Stratton, Michael R. (2000). Identification of the familial cylindromatosis tumour-suppressor gene. Nature Genetics, 25 (2), 160-165. doi: 10.1038/76006

  • Diagnosis of breast cancer using elastic-scattering spectroscopy: preliminary clinical results

    Bigio, Irving J., Bown, Stephen G., Briggs, Gavin, Kelley, Christine, Lakhani, Suni, Pickard, David, Ripley, Paul M., Rose, Ian G. and Saunders, Christobel (2000). Diagnosis of breast cancer using elastic-scattering spectroscopy: preliminary clinical results. Journal of Biomedical Optics, 5 (2), 221-228. doi: 10.1117/1.429990

  • How diagnosis with microarrays can help cancer patients

    Masters, John R. W. and Lakhani, Sunil R. (2000). How diagnosis with microarrays can help cancer patients. Nature, 404 (6781), 921-921. doi: 10.1038/35010139

  • Radiation safety of the sentinel lymph node technique in breast cancer

    Waddington, W. A., Taylor, I., Lakhani, S. R., Short, M. D. and Ell, P. J. (2000). Radiation safety of the sentinel lymph node technique in breast cancer. European Journal of Nuclear Medicine, 27 (4), 277-291.

  • Comparative genomic hybridization reveals extensive variation among different MCF-7 cell stocks

    Jones, Chris, Payne, Joachim, Wells, Dagan, Delhanty, Joy D. A., Lakhani, Sunil R. and Kortenkamp, Andreas (2000). Comparative genomic hybridization reveals extensive variation among different MCF-7 cell stocks. Cancer Genetics and Cytogenetics, 117 (2), 153-158. doi: 10.1016/S0165-4608(99)00158-2

  • Improving the reproducibility of the MCF-7 cell proliferation assay for the detection of xenoestrogens

    Payne, J., Jones, C., Lakhani, S. and Kortenkamp, A. (2000). Improving the reproducibility of the MCF-7 cell proliferation assay for the detection of xenoestrogens. Science of the Total Environment, 248 (1), 51-62. doi: 10.1016/S0048-9697(99)00479-9

  • Molecular analysis of phyllodes tumors reveals distinct changes in the epithelial and stromal components

    Sawyer, Elinor J., Hanby, Andrew M., Ellis, Paul, Lakhani, Sunil R., Ellis, Ian O., Boyle, Sue and Tomlinson, Ian P. M. (2000). Molecular analysis of phyllodes tumors reveals distinct changes in the epithelial and stromal components. American Journal of Pathology, 156 (3), 1093-1098. doi: 10.1016/S0002-9440(10)64977-2

  • The pathology of familial breast cancer: histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2

    Lakhani, Sunil R., Gusterson, Barry A., Jacquemier, Jocelyne, Sloane, John P., Anderson, Thomas J., van de Vijver, Marc J., Venter, Deon, Freeman, Alex, Antoniou, Antonios, McGuffog, Lesley, Smyth, Elizabeth, Steel, C. Michael, Haites, Nava, Scott, Rodney J., Goldgar, David, Neuhausen, Susan, Daly, Peter A., Ormiston, Wilma, McManus, Ross, Scherneck, Siegfried, Ponder, Bruce A. J., Futreal, P. Andrew, Peto, Julian, Stoppa-Lyonnet, Dominique, Bignon, Yves-Jean, Struewing, Jeffery P., Bishop, D. Timothy, Klijn, J.G.M., Devilee, Peter ... Stratton, Michael R. (2000). The pathology of familial breast cancer: histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2. Clinical Cancer Research, 6 (3), 782-789.

  • Lobular carcinoma in situ of the breast is not caused by constitutional mutations in the E-cadherin gene

    Rahman, N., Stone, J. G., Coleman, G., Gusterson, B., Seal, S., Lakhani, S. R., Ward, A., Nash, A., McKinna, A., A'Hern, R. and Houlston, R. S. (2000). Lobular carcinoma in situ of the breast is not caused by constitutional mutations in the E-cadherin gene. British Journal of Cancer, 82 (3), 568-570. doi: 10.1054/bjoc.1999.0965

  • Linkage and LOH studies in 19 cylindromatosis families show no evidence of genetic heterogeneity and refine the CYLD locus on chromosome 16q12-q13

    Takahashi, M., Rapley, E., Biggs, P. J., Lakhani, S. R., Cooke, D., Hansen, J., Blair, E., Hofmann, B., Siebert, R., Turner, G., Schrander-Stumpel, C., Beemer, F. A., van Vloten, W. A., Breuning, M. H., van den Ouweland, A., Halley, D., Delpech, B., Cleveland, M., Leigh, I., Chapman, P., Burn, J., Hohl, D., Gorog, J. P., Seal, S., Mangion, J., Warren, W., Bignell, G. and Stratton, M. R. (2000). Linkage and LOH studies in 19 cylindromatosis families show no evidence of genetic heterogeneity and refine the CYLD locus on chromosome 16q12-q13. Human Genetics, 106 (1), 58-65. doi: 10.1007/s004399900227

  • Genetic alterations in 'normal' luminal and myoepithelial cells of the breast

    Lakhani, Sunil R., Chaggar, Ranbir, Davies, Susan, Jones, Chris, Collins, Nadine, Odel, Christopher, Stratton, Michael R. and O'Hare, Michael J. (1999). Genetic alterations in 'normal' luminal and myoepithelial cells of the breast. Journal of Pathology, 189 (4), 496-503. doi: 10.1002/(SICI)1096-9896(199912)189:4<496::AID-PATH485>3.3.CO;2-4

  • re: Fibroadenoma with keratinous squamous cysts

    Colville, C. C., Krysa, J., Saunders, C., Schneidau, A. and Lakhani, S. R. (1999). re: Fibroadenoma with keratinous squamous cysts. Breast, 8 (6), 347-349. doi: 10.1054/brst.1999.0076

  • High level expression of differentially localized BAG-1 isoforms in some oestrogen receptor-positive human breast cancers

    Brimmell, M., Burns, J. S., Munson, P., Mcdonald, L., O'Hare, M. J., Lakhani, S. R. and Packham, G. (1999). High level expression of differentially localized BAG-1 isoforms in some oestrogen receptor-positive human breast cancers. British Journal of Cancer, 81 (6), 1042-1051. doi: 10.1038/sj.bjc.6690805

  • The pathology of hereditary breast cancer

    Lakhani, Sunil R. (1999). The pathology of hereditary breast cancer. Disease Markers, 15 (1-3), 113-114. doi: 10.1155/1999/459486

  • Atypical lobular hyperplasia and lobular carcinoma in situ: surgical and molecular pathology

    Lishman, S. C. and Lakhani, S. R. (1999). Atypical lobular hyperplasia and lobular carcinoma in situ: surgical and molecular pathology. Histopathology, 35 (3), 195-200. doi: 10.1046/j.1365-2559.1999.00815.x

  • Imprint cytology in sentinel node biopsy in breast cancer: is it reliable?

    Keshtgar, M. R. S., Kocjan, G., Lakhani, S. R. and Ell, P. J. (1999). Imprint cytology in sentinel node biopsy in breast cancer: is it reliable?. Nuclear Medicine Communications, 20 (7), 678-678. doi: 10.1097/00006231-199907000-00029

  • Does preoperative MRI influence the extent of surgical resection in conservative breast cancer surgery?

    Douek, M., Hall-Craggs, M. A., Lakhani, S. R. and Baum, M. (1999). Does preoperative MRI influence the extent of surgical resection in conservative breast cancer surgery?. Breast, 8 (2), 84-88. doi: 10.1016/S0960-9776(99)90005-X

  • The transition from hyperplasia to invasive carcinoma of the breast

    Lakhani, Sunil R. (1999). The transition from hyperplasia to invasive carcinoma of the breast. Journal of Pathology, 187 (3), 272-278. doi: 10.1002/(SICI)1096-9896(199902)187:3<272::AID-PATH265>3.0.CO;2-2

  • Allelic imbalance in familial and sporadic prostate cancer at the putative human prostate cancer susceptibility locus, HPC1

    Dunsmuir, W. D., Edwards, S. M., Lakhani, S. R., Young, M., Corbishley, C., Kirby, R. S., Dearnaley, D. P., Dowe, A., Ardern-Jones, A., Kelly, J., CRCBPG UK Familial Prostate Cancer Study Collaborators and Eeles, R. A. (1998). Allelic imbalance in familial and sporadic prostate cancer at the putative human prostate cancer susceptibility locus, HPC1. British Journal of Cancer, 78 (11), 1430-1433. doi: 10.1038/bjc.1998.703

  • Comparative genomic hybridization analysis of lobular carcinoma in situ and atypical lobular hyperplasia and potential roles for gains and losses of genetic material in breast neoplasia

    Lu, Yong-Jie, Osin, Pinchas, Lakhani, Sunil R., Di Palma, Silvana, Gusterson, Barry A. and Shipley, Janet M. (1998). Comparative genomic hybridization analysis of lobular carcinoma in situ and atypical lobular hyperplasia and potential roles for gains and losses of genetic material in breast neoplasia. Cancer Research, 58 (20), 4721-4727.

  • Immunohistochemical expression of BRCA2 protein and allelic loss at the BRCA2 locus in prostate cancer

    Edwards, Stephen M., Dunsmuir, William D., Gillett, Cheryl E., Lakhani, Sunil R., Corbishley, Catherine, Young, Martin, Kirby, Roger S., Dearnaley, David P., Dowe, Anna, Ardern-Jones, Audrey, Kelly, Jo, CRC/BPG UK Fmilial Prostate Cancer Study Collaborators, Spurr, Nigel, Barnes, Diana M. and Eeles, Rosalind A. (1998). Immunohistochemical expression of BRCA2 protein and allelic loss at the BRCA2 locus in prostate cancer. International Journal of Cancer, 78 (1), 1-7. doi: 10.1002/(SICI)1097-0215(19980925)78:1<1::AID-IJC1>3.0.CO;2-U

  • Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations

    Lakhani, Sunil R., Jacquemier, Jocelyne, Sloane, John P, Gusterson, Barry A., Anderson, Thomas J., van de Vijver, Marc J., Farid, Linda M., Venter, Deon, Antoniou, Antonios, Storfer-Isser, Amy, Smyth, Elizabeth, Steel, C. Michael, Haites, Neva, Scott, Rodney J., Goldgar, David, Neuhausen, Susan, Daly, Peter A., Ormiston, Wilma, McManus, Ross, Scherneck, Siegfried, Ponder, Bruce A. J., Ford, Debbie, Peto, Julian, Stoppa-Lyonnet, Dominique, Bignon, Yves-Jean, Struewing, Jeffrey P., Spurr, Nigel K., Bishop, D. Timothy, Klijn, J. G. M. ... Easton, Douglas F. (1998). Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations. Journal of the National Cancer Institute, 90 (15), 1138-1145. doi: 10.1093/jnci/90.15.1138

  • Can magnetic-resonance imaging help elucidate natural history of breast cancer multicentricity?

    Douek, Michael, Vaidya, Jayant S., Lakhani, Sunil R., Hall-Craggs, Margaret A., Baum, Michael and Taylor, Irving (1998). Can magnetic-resonance imaging help elucidate natural history of breast cancer multicentricity?. Lancet, 351 (9105), 801-802. doi: 10.1016/S0140-6736(98)24011-6

  • Breast disease in HIV positive males

    Keshtgar, M., Davidson, T., Soundy, V., Lakhani, S. R. and Miller, R. (1997). Breast disease in HIV positive males. The Breast, 6 (5), 281-283. doi: 10.1016/S0960-9776(97)90005-9

  • Pathology of familial breast cancer: differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases

    Breast Cancer Linkage Consortium*, Lakhani, Sunil R., Easton, Douglas F., Stratton, Michael R., Anderson, Thomas J., Farid, Linda M., Gusterson, B. A., Jaquemier, J., Sloane, J. P., Venter, D., VandeVijver, M. J., Bishop, D. T., Barkardottir, R. B., Bignon, Y. J., Cornelisse, C., ChangClaude, J., Daly, P. A., Devilee, P., Egilsson, V., Ford, D., Goldgar, D., Haites, N., Hamann, U., Klijn, J. G. M., Lasset, C., Lenoir, G., McManus, R., Neuhausen, S., Ormiston, W. ... Vasen, H. (1997). Pathology of familial breast cancer: differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases. Lancet, 349 (9064), 1505-1510.

  • Terminology for carcinoma-in-situ of the breast

    Quinn, Cecily, Ostrowski, Julian, Oxley, Dwight K., Sloane, J. P., Lakhani, S. R., Stratton, M. R., Baum, Michael, Simpson, Jean F., Jensen, Roy A. and Page, David L. (1996). Terminology for carcinoma-in-situ of the breast. Lancet, 347 (9010), 1259-1260. doi: 10.1016/S0140-6736(96)90774-6

  • The cylindromatosis gene (cyld1) on chromosome 16q may be the only tumour suppressor gene involved in the development of cylindromas

    Chapman, P., Lakhani, S. R. and Burn, J. (1996). The cylindromatosis gene (cyld1) on chromosome 16q may be the only tumour suppressor gene involved in the development of cylindromas. Oncogene, 12 (6), 1375-1377.

  • Detection of allelic imbalance indicates that a proportion of mammary hyperplasia of usual type are clonal, neoplastic proliferations

    Lakhani, S. R., Slack, D. N., Hamoudi, R. A., Collins, N., Stratton, M. R. and Sloane, J. P. (1996). Detection of allelic imbalance indicates that a proportion of mammary hyperplasia of usual type are clonal, neoplastic proliferations. Laboratory Investigation, 74 (1), 129-135.

  • Loss of heterozygosity in sporadic breast tumours at the BRCA2 locus on chromosome 13q12-q13

    Cleton-Jansen, A. -M., Collins, N., Lakhani, S. R., Weissenbach, J., Devilee, P., Cornelisse, C. J. and Stratton, M. R. (1995). Loss of heterozygosity in sporadic breast tumours at the BRCA2 locus on chromosome 13q12-q13. British Journal of Cancer, 72 (5), 1241-1244. doi: 10.1038/bjc.1995.493

  • Atypical ductal hyperplasia of the breast: Clonal proliferation with loss of heterozygosity on chromosomes 16q and 17p

    Lakhani, S. R., Collins, N., Stratton, M. R. and Sloane, J. P. (1995). Atypical ductal hyperplasia of the breast: Clonal proliferation with loss of heterozygosity on chromosomes 16q and 17p. Journal of Clinical Pathology, 48 (7), 611-615. doi: 10.1136/jcp.48.7.611

  • neu Overexpression correlates with extent of disease in large cell ductal carcinoma in situ of the breast

    De Potter, Christian R., Schelfhout, Anne-Marie, Verbeeck, Paul, Lakhani, Sunil R., Brunken, Roland, Van Den Tweel, Jan G., Schauer, Alfred J. and Sloane, John P. (1995). neu Overexpression correlates with extent of disease in large cell ductal carcinoma in situ of the breast. Human Pathology, 26 (6), 601-606. doi: 10.1016/0046-8177(95)90163-9

  • Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13

    Collins, N., McManus, R., Wooster, R., Mangion, J., Seal, S., Lakhani, S. R., Ormiston, W., Daly, P. A., Ford, D., Easton, D. F. and Stratton, M. R. (1995). Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13. Oncogene, 10 (8), 1673-1675.

  • LOSS OF HETEROZYGOSITY IN LOBULAR CARCINOMA IN-SITU OF THE BREAST

    LAKHANI, , COLLINS, N, SLOANE, JP and STRATTON, MR (1995). LOSS OF HETEROZYGOSITY IN LOBULAR CARCINOMA IN-SITU OF THE BREAST. Journal of Clinical Pathology-Clinical Molecular Pathology Edition, 48 (2), M74-M78.

  • Loss of heterozygosity in ductal carcinoma in situ of the breast

    Stratton, M. R., Collins, N., Lakhani, S. R. and Sloane, J. P. (1995). Loss of heterozygosity in ductal carcinoma in situ of the breast. Journal of Pathology, 175 (2), 195-201. doi: 10.1002/path.1711750207

  • Malignant myoepithelioma (Myoepithelial carcinoma) of the breast - a detailed cytokeratin study

    Lakhani, S. R., Ohare, M. J., Winehouse, J., Gazet, J. C. and Sloane, J. P. (1995). Malignant myoepithelioma (Myoepithelial carcinoma) of the breast - a detailed cytokeratin study. Journal of Clinical Pathology, 48 (2), 164-167. doi: 10.1136/jcp.48.2.164

  • Intravascular malignant lymphomatosis (angiotropic large-cell lymphoma). A case report with evidence for T-cell lineage with polymerase chain reaction analysis

    Lakhani, S. R. and Hall, J. M. (1994). Intravascular malignant lymphomatosis (angiotropic large-cell lymphoma). A case report with evidence for T-cell lineage with polymerase chain reaction analysis. Histopathology, 25 (3), 283-286. doi: 10.1111/j.1365-2559.1994.tb01331.x

  • Renal allograft dysfunction due to vesicoureteric obstruction by nodular malakoplakia

    Stern, S. C. M., Lakhani, S. and Morgan, S. H. (1994). Renal allograft dysfunction due to vesicoureteric obstruction by nodular malakoplakia. Nephrology, Dialysis, Transplantation, 9 (8), 1188-1190.

  • Early clinical pathologists: Robert Koch (1843-1910)

    Lakhani, S. R. (1993). Early clinical pathologists: Robert Koch (1843-1910). Journal of Clinical Pathology, 46 (7), 596-598.

  • Early clinical pathologists: Edward Jenner (1749-1823)

    Lakhani, S. R. (1992). Early clinical pathologists: Edward Jenner (1749-1823). Journal of Clinical Pathology, 45 (9), 756-758. doi: 10.1136/jcp.45.9.756

  • Parathyroid hormone related protein in hypercalcaemia of Hodgkin's disease

    Bolodeoku, J., Lakhani, S., Dunne, F., Ratcliffe, W. A., Clarke, M. and Barron, J. L. (1992). Parathyroid hormone related protein in hypercalcaemia of Hodgkin's disease. Journal of Clinical Pathology, 45 (6), 541-542. doi: 10.1136/jcp.45.6.541

  • Early clinical pathologists 4: Rudolf Virchow (1821-1902)

    Tildsley, G. J. and Lakhani, S. (1992). Early clinical pathologists 4: Rudolf Virchow (1821-1902). Journal of Clinical Pathology, 45 (1), 6-7. doi: 10.1136/jcp.45.1.6

  • Early clinical pathologists 4: John Hunter (1728-1793)

    Lakhani, S. (1991). Early clinical pathologists 4: John Hunter (1728-1793). Journal of Clinical Pathology, 44 (8), 621-623. doi: 10.1136/jcp.44.8.621

  • Breast conserving surgery in the management of in situ breast carcinoma

    Graham, M. D., Lakhani, S. and Gazet, J. C. (1991). Breast conserving surgery in the management of in situ breast carcinoma. European Journal of Surgical Oncology, 17 (3), 258-264.

  • Enhanced anti-tumour activity of carmustine (BCNU) with tumour necrosis factor in vitro and in vivo

    Jones, A. L., Millar, J. L., Millar, B. C., Powell, B., Selby, P., Winkley, A., Lakhani, S., Gore, M. E. and McElwain, T. J. (1990). Enhanced anti-tumour activity of carmustine (BCNU) with tumour necrosis factor in vitro and in vivo. British Journal of Cancer, 62 (5), 776-780. doi: 10.1038/bjc.1990.378

  • How do we teach pathology? The teaching of pathology at St. George's Hospital Medical School, London

    Lakhani, S., Chambers, T. J. and Dilly, S. A. (1990). How do we teach pathology? The teaching of pathology at St. George's Hospital Medical School, London. Journal of Pathology, 161 (2), 179-181. doi: 10.1002/path.1711610214

  • Choroid-plexus papillomas - immunohistochemical study

    Lakhani, S., Hangartner, J. R. W. and Dilly, S. A. (1990). Choroid-plexus papillomas - immunohistochemical study. Histopathology, 16 (4), 419-419. doi: 10.1111/j.1365-2559.1990.tb01153.x

  • Chemotherapy for malignant melanoma: Combinations and high doses produce more responses without survival benefit

    Lakhani, S., Selby, P., Bliss, J. M., Perren, T. J., Gore, M. E. and McElwain, T. J. (1990). Chemotherapy for malignant melanoma: Combinations and high doses produce more responses without survival benefit. British Journal of Cancer, 61 (2), 330-334. doi: 10.1038/bjc.1990.65

  • Dose-dependent acute hepatitis associated with administration of high dose methotrexate

    Banerjee, A. K., Lakhani, S., Vincent, M. and Selby, P. (1988). Dose-dependent acute hepatitis associated with administration of high dose methotrexate. Human Toxicology, 7 (6), 561-562. doi: 10.1177/096032718800700608

  • Infused vincristine and adriamycin with high dose methylprednisolone (VAMP) in advanced previously treated multiple myeloma patients

    Forgeson, G. V., Selby, P., Lakhani, S., Zulian, G., Viner, C., Maitland, J. and McElwain, T. J. (1988). Infused vincristine and adriamycin with high dose methylprednisolone (VAMP) in advanced previously treated multiple myeloma patients. British Journal of Cancer, 58 (4), 469-473. doi: 10.1038/bjc.1988.243

  • Amebic-colitis - an often misdiagnosed disease

    Lakhani, S. and Jones, P. W. (1987). Amebic-colitis - an often misdiagnosed disease. The Practitioner, 231 (1438), 1431-1432.

  • Effect of a surgical day unit on waiting lists

    Lakhani, S., Leach, R. D. and Jarrett, P. E. M. (1987). Effect of a surgical day unit on waiting lists. Journal of the Royal Society of Medicine, 80 (10), 628-629.

  • Intensive therapy for medical complications of haematological malignancy at The Royal Marsden Hospital

    Banerjee, A., Lakhani, S., McElwain, T. J. and Powles, R. (1987). Intensive therapy for medical complications of haematological malignancy at The Royal Marsden Hospital. Intensive Care Medicine, 13 (3), 213-214.

  • Differences among Asian patients

    Shaunak, S., Lakhani, S. R., Abraham, R. and Maxwell, J. D. (1986). Differences among Asian patients. BMJ, 293 (6555), 1169-1169. doi: 10.1136/bmj.293.6555.1169

  • Razoxane and leukemia

    Lakhani, S., Davidson, R. N., Hiwaizi, F. and Marsden, R. A. (1984). Razoxane and leukemia. Lancet, 2 (8397), 288-289.

  • Characterization of the inhibitory effects of hyperprolactinaemia on the mechanism controlling LH secretion in chronically ovariectomized rats

    Carter, D. A., Lakhani, S. and Whitehead, S. A. (1983). Characterization of the inhibitory effects of hyperprolactinaemia on the mechanism controlling LH secretion in chronically ovariectomized rats. Journal of Reproduction and Fertility, 69 (1), 57-64.

  • Iron in flour

    Lakhani, S. and Sondhi, R. (1983). Iron in flour. Lancet, 2 (8356), 967-967.

Conference Publication

  • HER2 in situ hybridization testing in breast cancer: applying algorithm-assisted assessment to reduce interobserver variability in difficult cases

    Gough, Madeline, Liu, Cheng, Srinivasan, Bhuvana, Wilkinson, Lisa, Dunk, Louisa, Yang, Yuanhao, Tuffaha, Haitham, Kryza, Thomas, Hooper, John D., Lakhani, Sunil R. and Snell, Cameron Edward (2023). HER2 in situ hybridization testing in breast cancer: applying algorithm-assisted assessment to reduce interobserver variability in difficult cases. 2023 ASCO Annual Meeting, Chicago, IL United States, 2-6 June 2023. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2023.41.16_suppl.e13561

  • Branchioma: A Series of 23 Cases Illustrating Frequent Loss of the Retinoblastoma 1 (Rb1)

    Baneckova, Martina, Thompson, Lester, Hyrcza, Martin, Vanecek, Tomas, Grossmann, Petr, Michal, Michael, Hajkova, Veronika, Taheri, Touraj, Rupp, Niels, Suster, David, Lakhani, Sunil, Nikolov, Dimitar Hadzi, Skalova, Alena, Michal, Michal and Agaimy, Abbas (2023). Branchioma: A Series of 23 Cases Illustrating Frequent Loss of the Retinoblastoma 1 (Rb1). 112th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP), Mexico, Mar 11-16, 2023. NEW YORK: ELSEVIER SCIENCE INC.

  • Diff-Quik smears from EBUS TBNA procedures: Evaluating measures of tumour cellularity and feasibility of whole genome sequencing (WGS)

    Fielding, David, Dalley, Andrew, Singh, Mahendra, Nandakumar, Lakshmy, Lakis, Vanessa, Chittoory, Haarika, Bashirzadeh, Farzad, Bint, Michael, Pahoff, Carl, Son, Jung, Hodgson, Alan, Sharma, Sowmya, Godbolt, David, Coleman, Kylie, Whitfield, Lenore, Waddell, Nicola, Lakhani, Sunil, Nones, Katia, Hartel, Gunter and Simpson, Peter (2023). Diff-Quik smears from EBUS TBNA procedures: Evaluating measures of tumour cellularity and feasibility of whole genome sequencing (WGS). HOBOKEN: WILEY.

  • Implementation of precision oncology for breast cancer care in Brisbane: Q-IMPROvE

    McCart Reed, Amy, McCurry, Therese, Simpson, Peter, Inglis, Po-Ling, Ung, Owen, Murugappan, Kowsalya, Waddell, Nic, Snell, Cameron, Woodward, Natasha, Middleton, Kathryn, Walpole, Euan, O'Byrne, Ken, Cuff, Katharine, Andelkovic, Vladimir, Roberts, Kate, Steinke, Karin, Santamaria, Gorane, McCarthy, Nicole, Mar Fan, Helen, Kalinowski, Lauren and Lakhani, Sunil (2021). Implementation of precision oncology for breast cancer care in Brisbane: Q-IMPROvE. Brisbane Cancer Conference , Brisbane, QLD Australia, 25-26 Nov 2021.

  • Implementation of precision oncology for breast cancer care in Brisbane: Q-IMPROvE

    McCart Reed, Amy, McCurry, Therese, Simpson, Peter, Inglis, Po-ling, Ung, Owen, Murugappan, Kowsalya, Waddell, Nic, Snell, Cameron, Woodward, Natasha, Middleton, Kathryn, Walpole, Euan, O'Byrne, Ken, Cuff, Katharine, Andelkovic, Vlad, Roberts, Kate, Steinke, Karin, Santamaria, Gorane, McCarthy, Nicole, Mar Fan, Helen, Kalinowski, Lauren and Lakhani, Sunil (2021). Implementation of precision oncology for breast cancer care in Brisbane: Q-IMPROvE. Herston Symposium, Brisbane, QLD Australia, September 2021.

  • OlympiA: A phase III, multicenter, randomized, placebo-controlled trial of adjuvant olaparib after (neo)adjuvant chemotherapy in patients with germline BRCA1/2 mutations and high-risk HER2-negative early breast cancer

    Tutt, Andrew, Garber, Judy Ellen, Kaufman, Bella, Viale, Giuseppe, Fumagalli, Debora, Rastogi, Priya, Gelber, Richard D., de Azambuja, Evandro, Fielding, Anitra, Gelpi, Judith Balmana, Gelmon, Karen A., Baker, Nigel, Arahmani, Amal, Senkus-Konefka, Elzbieta, Mc Fadden, Eleanor, Karantza, Vassiliki, Lakhani, Sunil R., Yothers, Greg, Campbell, Christine and Geyer, Charles E. (2021). OlympiA: A phase III, multicenter, randomized, placebo-controlled trial of adjuvant olaparib after (neo)adjuvant chemotherapy in patients with germline BRCA1/2 mutations and high-risk HER2-negative early breast cancer. Virtual Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Electr Network, Jun 04-08, 2021. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. doi: 10.1200/JCO.2021.39.15_suppl.LBA1

  • Calcium communication in an in vitro model of breast cancer brain metastases

    Chalmers, Silke B., Sadras, Francisco, Saunus, Jodi , Lakhani, Sunil , Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2020). Calcium communication in an in vitro model of breast cancer brain metastases. ASCEPT-APSA Joint virtual scientific meeting 2020, Virtual meeting, 24-26 November 2020.

  • Remodelling of calcium influx pathways in breast cancer associated fibroblasts

    Sadras, Francisco, Stewart, Teneale A., Robitaille, Melanie, Peters, Amelia A., Kalita-de Croft, Priyakshi, Soon, Patsy, Saunus, Jodi M., Lakhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2020). Remodelling of calcium influx pathways in breast cancer associated fibroblasts. 2019 San Antonio Breast Cancer Symposium, San Antonio, TX United States, 10-14 December 2019. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.sabcs19-p6-06-15

  • Dissecting the heterogeneity of metaplastic breast cancer: a morphological, immunohistochemical and genomic analysis of a large cohort

    Reed, A. E. McCart, Kalaw, E., Nones, K., Bettington, M., Lim, M., Bennett, J., Johnstone, K., Kutasovic, J. R., Kazakoff, S., Xu, Q. C., Saunus, J. M., Reid, L. E., Black, D., Niland, C., Ferguson, K., Gresshoff, I., Raghavendra, A., Liu, J. C., Kalinowski, L., Reid, A. S., Davidson, M., Pearson, J. V., Yamaguchi, R., Harris, G., Tse, G., Papadimos, D., Pathmanathan, R., Pathmanathan, N., Tan, P. H. ... Lakhani, S. R. (2019). Dissecting the heterogeneity of metaplastic breast cancer: a morphological, immunohistochemical and genomic analysis of a large cohort. San Antonio Breast Cancer Symposium, San Antonio, TX, United States, 4-8 December 2018. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS18-P3-08-03

  • Assessment of Ca2+ channels and pumps in brain-seeking breast cancer cell lines

    Lim, Darren Z. R. , Chalmers, Silke B. , Robitaille, Melanie , Saunus, Jodi M. , Lakhani, Sunil R. , Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2019). Assessment of Ca2+ channels and pumps in brain-seeking breast cancer cell lines. ASCEPT-PAGANZ Joint Scientific Meeting, Queenstown, New Zealand, 25-29 November 2019. Hamilton Central, QLD, Australia: ASCEPT.

  • Innovation in diagnosis and treatment of brain metastases using multifunctional nanomedicines

    Saunus, J. M., Lim, M., Puttick, S., Croft, P. Kalita-de, Houston, Z. H., Jones, M. L., Latter, M. J., Campbell, L. C., Thomas, P., Jeffree, R. L., Rose, S. E., Mahler, S. M., Thurecht, K. J., Scott, A. M. and Lakhani, S. R. (2019). Innovation in diagnosis and treatment of brain metastases using multifunctional nanomedicines. San Antonio Breast Cancer Symposium, San Antonio, Texas, 4-8 December 2018. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS18-P1-19-02

  • LobSig, a prognostic signature for Invasive Lobular Carcinoma

    McCart Reed, Amy E., Lal, Samir, Kutasovic, Jamie R., Wockner, Leesa, Robertson, Alan, de Croft, Priyakshi Kalıta, Dalley, Andrew, Coorey, Craig P., Kuo, Luyu, Ferguson, Kaltin, Niland, Colleen, Miller, Gregory, Johnson, Julie, Reid, Lynne E., Males, Renique, Saunus, Jodi M., Chenevix-Trench, Georgia, Coin, Lachlan, Lakhani, Sunil R. and Simpson, Peter T. (2019). LobSig, a prognostic signature for Invasive Lobular Carcinoma. 7th International PacRim Breast and Prostate Cancer Meeting, Barossa Novotel, South Australia, Australia, 17-20 March 2019.

  • Remodeling of calcium influx pathways in models of cancer associated fibroblasts in breast cancer

    Monteith, Greg, Sadras, Francisco, Stewart, Teneale, Robitaille, Melanie, Kalita-de Croft, Priyakshi, Soon, Patsy, Saunus, Jodi, Lakhani, Sunil and Roberts-Thomson, Sarah (2019). Remodeling of calcium influx pathways in models of cancer associated fibroblasts in breast cancer. AACR Annual Meeting on Bioinformatics, Convergence Science, and Systems Biology, Atlanta, GA United States, 29 March - 3 April 2019. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS18-99

  • Using whole genome sequencing and somatic mutation signatures to unravel insight into familial breast cancer aetiology

    Simpson, P., Nones, K., Johnson, J., Newell, F., Patch, A-M, Thorne, H., Kazakoff, S., De Luca, X., Parsons, M., Ferguson, K., Reid, L., Reed, A. McCart, Srihari, S., Lakis, V., Davidson, A., Mukhopadhyay, P., Holmes, O., Xu, Q., Wood, S., Leonard, C., Beasley, J., Degasperi, A., Nik-Zainal, S., Ragan, M., Spurdle, A., Khanna, K. K., Lakhani, S., Pearson, J., Chenevix-Trench, G. and Waddell, N. (2019). Using whole genome sequencing and somatic mutation signatures to unravel insight into familial breast cancer aetiology. San Antonio Breast Cancer Symposium, San Antonio, TX, United States, 4-8 December 2018. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS18-P5-10-01

  • Expression of ARGLU and FBXL3 is highly prognostic for invasive lobular carcinoma

    Coorey, Craig, Lal, Samir, Kutasovic, Jamie, Niland, Colleen, Ferguson, Kaltin, Kuo, Lu Yu, Reid, Lynne, Evans, Elizabeth, Porter, Alan, Lakhani, Sunil, McCart Reed, Amy and Simpson, Peter (2018). Expression of ARGLU and FBXL3 is highly prognostic for invasive lobular carcinoma. Pathology Update 2018, Sydney, NSW Australia, 2-4 March 2018. London, United Kingdom: Lippincott Williams & Wilkins. doi: 10.1016/j.pathol.2017.12.166

  • Proteomic analysis of the mouse brain stromal microenvironment: a milieu intérieur of metabolic reprogramming

    Kalita de Croft, Priyakshi , Straube, Jasmin , Al-Ejeh, Fares , M Saunus,Jodi and R Lakhani, Sunil (2018). Proteomic analysis of the mouse brain stromal microenvironment: a milieu intérieur of metabolic reprogramming. 30th Lorne Cancer Conference 2018, Lorne, Victoria, Australia, 8th-11th February, 2018.

  • Investigating the HER2-3 dimer as a theranostic target in brain metastases

    Saunus, J. M., Croft, P. K.-D., Lee, F. T., Al-Ejeh, F., Lim, M., Ensbey, K., Niland, C., Jeffree, R. L., Thomas, P., Day, B. W., Rose, S., Scott, A. M. and Lakhani, S. R. (2017). Investigating the HER2-3 dimer as a theranostic target in brain metastases. 16th Biennial Congress of the Metastasis Research Society, Chengdu, China, 16-20 September 2016. Dordrecht, Netherlands: Springer. doi: 10.1007/s10585-017-9843-0

  • An integrated molecular analysis of invasive lobular carcinoma

    Lal, S., Reed, A. McCart, Nones, K., Wockner, L., Song, S., Lakhani, S. and Simpson, P. (2017). An integrated molecular analysis of invasive lobular carcinoma. 39th Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, 6-10 December 2016. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS16-P1-05-16

  • Brocade: The National Breast Cancer Foundation Repository of Primary Tumours and Metastases from Breast Cancer Patients

    Anderson, Robin L., Swarbrick, Alex, Johnstone, Ricky, Chua, Boon, Gill, Anthony, Saunders, Christobel, Lakhani, Sunil, Lim, Elgene, Loi, Sherene, O'Toole, Sandra A., Khanna, Kum Kum, Devereux, Lisa, Harvey, Kate and Reed, Amy McCart (2017). Brocade: The National Breast Cancer Foundation Repository of Primary Tumours and Metastases from Breast Cancer Patients. COSA's 44th Annual Scientific Meeting: Immunotherapy: Molecules and Moutains, Darling Harbour, Sydney, NSW, 13–15 November 2017. Hoboken, NJ United States: Wiley.

  • Diffquik Stained Cytology Smears Provide Improved Malignant Cell Dna Yields From Lymph Nodes At Endobronchial Ultrasound Transbronchial Needle Aspiration (Ebus-Tbna)

    Fielding, D., Dalley, A., Bashirzadeh, F., Singh, M., Nandakumar, L., Reed, McCart A., Black, D., Waddell, N., Kazakoff, Stephen, Nones, Katia, Pearson, John, Lakhani, S. and Simpson, P. (2017). Diffquik Stained Cytology Smears Provide Improved Malignant Cell Dna Yields From Lymph Nodes At Endobronchial Ultrasound Transbronchial Needle Aspiration (Ebus-Tbna). ANZSRS/TSANZ Annual Scientific Meeting , Canberra, Australia, 24-28 March 2017. Richmond, VIC, Australia: Wiley-Blackwell.

  • Immunohistochemical evaluation of FOXA1 expression and its correlation with breast cancer-specific survival: queensland follow up cohort

    Dedina, Liana, Kutasovic, Jamie R., McCart Reed, Amy E., Simpson, Peter T. and Lakhani, Sunil R. (2017). Immunohistochemical evaluation of FOXA1 expression and its correlation with breast cancer-specific survival: queensland follow up cohort. Pathology Update 2017, Sydney Australia, 24 - 26 February 2017. London, United Kingdom: Lippincott Williams & Wilkins. doi: 10.1016/j.pathol.2016.12.174

  • Mixed ductal-lobular carcinomas of the breast: Abrogated cell adhesion in the clonal evolution from ductal to lobular morphology

    Reed, A. E. McCart, Kutasovic, J. R., Nones, K., da Silva, L., Melville, L., Jayanthan, J., Vargas, A. C., Reid, L. E., Saunus, J. M., Cummings, M. M., Porter, A., Evans, E., Waddell, N., Lakhani, S. R. and Simpson, P. T. (2017). Mixed ductal-lobular carcinomas of the breast: Abrogated cell adhesion in the clonal evolution from ductal to lobular morphology. San Antonio Breast Cancer Symposium, San Antonio, TX, United States, 6-10 December 2016. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS16-P1-07-08

  • RNA immunoprecipitation reveals lncRNA-protein interactions in basal-like breast cancer

    Northwood, K., Saunus, J., Milevskiy, M., Lakhani, S. and Brown, M. (2017). RNA immunoprecipitation reveals lncRNA-protein interactions in basal-like breast cancer. San Antonio Breast Cancer Symposium, San Antonio TX, United States, 6-10 December 2016. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS16-P1-04-05

  • The development of personalized diagnostic tests and therapeutic strategies in breast cancer

    Kutasovic, J. R., Rozali, E., Miranda, M., Lakhani, S. R. and Al-Ejeh, F. (2017). The development of personalized diagnostic tests and therapeutic strategies in breast cancer. San Antonio Breast Cancer Symposium, San Antonio, TX United States, 06-10 December 2016. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS16-P6-09-47

  • Targeting Her Receptors in Brain Metastases

    Lakhani, Sunil R. (2016). Targeting Her Receptors in Brain Metastases. HOBOKEN: WILEY-BLACKWELL.

  • Clinical Guidance for Management of Lobular Carcinoma in Situ

    Norris, S., Anderson, K., Jack, B., Milch, V., Lakhani, S. and Zorbas, H. (2016). Clinical Guidance for Management of Lobular Carcinoma in Situ. HOBOKEN: WILEY-BLACKWELL.

  • An integrative analysis of invasive lobular breast cancer

    Lal, Samir, McCart Reed, Amy E, Nones, Katia, Wockner Leesa, Song, Sarah, Waddell, Nic, Lakhani, Sunil and Simpson, Peter t (2016). An integrative analysis of invasive lobular breast cancer. Lorne Cancer Conference, Lorne VIC, Australia, February 11-13th 2016.

  • Investigating the Her2-3 dimer as a theranostic target in brain metastases

    Saunus, Jodi M., Kalita-de Croft, Priyakshi, Lee, F. T., Al-Ejeh, Fares, Lim, Malcolm, Ensbey, Kathleen, Niland, Colleen, Jeffree, Rosalind L., Thomas, Paul, Day, Bryan W., Rose, Stephen, Scott, Andrew M. and Lakhani, Sunil R. (2016). Investigating the Her2-3 dimer as a theranostic target in brain metastases. COSA's 43 and ANZBCTG's 38 Annual Scientific Meetings. Partners for Progress in Breast Cancer Research and Care, Gold Coast, QLD Australia, 15-17 November 2016. Chichester, West Sussex United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/ajco.12646

  • Next Generation Sequencing On Endobronchial Ultrasound Transbronchial Needle Aspirate Lymph Node Specimens in Lung Cancer Shows a High Incidence of Mutations and Consistency with Single Gene Testing

    Fielding, D., Bashirzadeh, F., Singh, M., Nandakumar, L., Reed, Mccart A., Black, D., Dalley, A., Pearson, J., Nones, K., Waddell, N., Simpson, P. and Lakhani, S. (2016). Next Generation Sequencing On Endobronchial Ultrasound Transbronchial Needle Aspirate Lymph Node Specimens in Lung Cancer Shows a High Incidence of Mutations and Consistency with Single Gene Testing. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Perth, WA Australia, 1–6 April 2016. Wiley. doi: 10.1111/resp.12754_12

  • The development of personalized diagnostic tests and therapeutic strategies in breast cancer

    Kutasovic, Jamie R., Rozali, Esdy, Miranda, Mariska, Lakhani, Sunil R. and Al-Ejeh, Fares (2016). The development of personalized diagnostic tests and therapeutic strategies in breast cancer. COSA's 43rd and ANZBCTG's 38th Annual Scientific Meetings. Partners for Progress in Breast Cancer Research and Care, Gold Coast, QLD Australia, 15-17 November 2016. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.

  • Breast cancer metastasis to gynaecological organs: impacting young women diagnosed with a luminal tumour subtype

    Kutasovic, Jamie, Reed, Amy McCart, Sim, Sarah, Cummings, Margaret, Lakhani, Sunil and Simpson, Peter (2015). Breast cancer metastasis to gynaecological organs: impacting young women diagnosed with a luminal tumour subtype. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, June 28th–July 1st, 2014. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/s10585-015-9708-3

  • Erk5 as a therapeutic target in triple negative breast cancer (TNBC)

    Miranda, Mariska Sauzine, Al Ejeh, Fares, Shi, Wei, Simpson, Peter, Lakhani, Sunil and Khanna, Kum Kum (2015). Erk5 as a therapeutic target in triple negative breast cancer (TNBC). 37th Annual CTRC-AACR San Antonio Breast Cancer Symposium, San Antonio, TX, United States, 9-13 December 2014. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS14-P6-03-11

  • Exploring the HER3 tyrosine kinase as a therapeutic target for treatment of brain metastases

    Saunus, Jodi M., Momeny, Majid, Da Silva, Leonard, Reid, Lynne, Holland, Jane D., Birchmeier, Walter, Jat, Parmjit, Brandner, Sebastian, Al-Ejeh, Fares, Khanna, Kum Kum, Chenevix-Trench, Georgia, Simpson, Peter T. and Lakhani, Sunil R. (2015). Exploring the HER3 tyrosine kinase as a therapeutic target for treatment of brain metastases. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, 28 June - 01 July 2014. Dordrecht, Netherlands: Springer. doi: 10.1007/s10585-015-9708-3

  • Flipping pathology and its impact on learning in second year medical students at University of Queensland, School of Medicine, Australia

    Koteeswaran, Raja, Deborah Smith, Ekta Bhutada, Simpson, Peter T., Emma Bartle, Julie Elizabeth Ayre, Galea, Melanie, Joanne Lester, Bowker, Shari and Lakhani, Sunil (2015). Flipping pathology and its impact on learning in second year medical students at University of Queensland, School of Medicine, Australia. The 2015 AAMC Medical Education Meeting, Baltimore, Maryland, USA, 10-12 November 2015.

  • Genomic and transcriptomic landscapes of human brain metastases

    Saunus, J. M., Quinn, M. C. J., Patch, A. M., Pearson, J. V., Bailey, P. J., Cloonan, N., Nones, K., Miller, D., Mariasegaram, M., Lau, Q., Jeffree, L., Khanna, K. K., Chenevix-Trench, G., Grimmond, S. M., Simpson, P. T., Waddell, N. and Lakhani, S. R. (2015). Genomic and transcriptomic landscapes of human brain metastases. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, June 28th–July 1st, 2014. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/s10585-015-9708-3

  • The inhibitor of differentiation proteins mediate tumour-initiating properties and metastasis in breast cancer

    Nair, Radhika, Teo, Wee Siang, Ye, Sunny, McFarland, Andrea, Harvey, Kate, Roden, Daniel, Junankar, Simon, Baker, Laura, Yang, Jessica, Fluke, Nicola, Millar, Ewan, Mellick, Albert, Naylor, Matthew, Ormandy, Christopher, Lakhani, Sunil, O'Toole, Sandra and Swarbrick, Alexander (2015). The inhibitor of differentiation proteins mediate tumour-initiating properties and metastasis in breast cancer. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, June 28th–July 1st, 2014. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/s10585-015-9708-3

  • The role of epithelial to mesenchymal plasticity in driving the invasive capacity of 'lobular-like' tumour cell differentiation in breast cancer

    Reed, McCart A. E., Kutasovic, J. R., Vargas, A. C., Da Silva, L., Jayanthan, J., Al-Murrani, A., Reid, L. E., Evans, E., Porter, A., Lakhani, S. R. and Simpson, P. T. (2015). The role of epithelial to mesenchymal plasticity in driving the invasive capacity of 'lobular-like' tumour cell differentiation in breast cancer. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, June 28th–July 1st, 2014. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/s10585-015-9708-3

  • Calcium efflux pump, PMCA2, in human breast tissue with lactational change and as a therapeutic target in breast cancer

    Peters, Amelia A., Lee, Wei C., Dray, Eloise, Smart, Chanel E., Reid, Lynne , da Silva, Leonard , Lakhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2014). Calcium efflux pump, PMCA2, in human breast tissue with lactational change and as a therapeutic target in breast cancer. 2nd Annual Congress of The European Society for Translational Medicine Medicine, Vienna, Austria, 22-25 September 2014.

  • Id4 Controls Mammary Stem Cells and Marks Breast Cancers with a Stem Cell Like Phenotype

    Junankar, Simon, Baker, Laura, Roden, Daniel, Nair, Radhika, Elsworth, Ben, Lakhani, Sunil, Simpson, Peter, Ormandy C, Chris, O'Toole, Sandra and Swarbrick, Alexander (2014). Id4 Controls Mammary Stem Cells and Marks Breast Cancers with a Stem Cell Like Phenotype. Sydney Cancer Conference 2014, University of Sydney, NSW Australia, 26 November 2014. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/ajco.12282

  • PMCA2 in human breast tissue with lactational change and in human breast cancer cells

    Peters, Amelia A., Lee, Wei C., Dray, Eloise , Smart, Chanel E., Reid, Lynne , da Silva, Leonard , Lakhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2014). PMCA2 in human breast tissue with lactational change and in human breast cancer cells. 13th International Meeting of the European Calcium Society, Aix-en-Provence, France, 13-17 September 2014.

  • Update on WHO breast classification: 2 years on

    Lakhani, Sunil R. (2014). Update on WHO breast classification: 2 years on. IAP 2014: 30th Congress of the International Academy of Pathology 2014, Bangkok, Thailand, 5-10 October, 2014. London, United Kingdom: Lippincott Williams & Wilkins. doi: 10.1097/01.PAT.0000454053.47289.16

  • Abrogated cell-cell adhesion in the phenotypic drift from ductal to lobular breast cancer types

    Da Silva, Leonard, McCart Reed, Amy E., Kutasovic, Jamie R., Vargas, Ana Cristina, Jayanthan, Janani, Reid, Lynne, Fritz, Brian, Cummings, Margaret C., Porter, Alan, Evans, Elizabeth, Lakhani, Sunil R. and Simpson, Peter T. (2012). Abrogated cell-cell adhesion in the phenotypic drift from ductal to lobular breast cancer types. 24th Lorne Cancer Conference 2012, Lorne, VIC, Australia, 9-11 February 2012.

  • Calcium channel transient receptor potential V6 (TRPV6) as a potential therapeutic target for some breast cancers

    Peters, A. A., Simpson, P. T., Bassett, J. J., Lee, J. M., Song, S., Parat, M. O., Lakhani, S. R., Kenny, P. A., Roberts-Thomson, S. J. and Monteith, G. R. (2012). Calcium channel transient receptor potential V6 (TRPV6) as a potential therapeutic target for some breast cancers. 24th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Dublin, Ireland, 6-9 November 2012. Oxford, United Kingdom: Pergamon. doi: 10.1016/S0959-8049(12)72328-6

  • Dissecting the role of the inhibitor of differentiation 1 in breast cancer metastasis and characterization of pathways controlling breast cancer stem cell phenotype

    Teo, W., Nair, R., McFarland, A., Ye, S., Mellick, A., Lakhani, S. and Swarbrick, A. (2012). Dissecting the role of the inhibitor of differentiation 1 in breast cancer metastasis and characterization of pathways controlling breast cancer stem cell phenotype. 22nd Biennial Congress of the European Association for Cancer Research, Barcelona Spain, 07-10 July 2012. Oxford, United Kingdom: Pergamon.

  • Immunohistochemical analysis of PMCA2 expression in normal and malignant human breast tissues

    Peters, Amelia, Lee, Wei C., Smart, Chanel E., Reid, Lynne, da Silva, Leonard, Lakhani, Sunil, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2012). Immunohistochemical analysis of PMCA2 expression in normal and malignant human breast tissues. Joint ASCEPT-APSA 2012 Conference, Medication Safety, Sydney, Australia, 2-5 December 2012.

  • Role of HER3 in brain metastases from primary breast cancer

    Saunus, Jodi M., Da Silva, Leonard, Momeny, Majid, Morrison, Brian, Lane, Annette, Smart, Chanel, Al-Ejeh, Fares, Khanna, Kum Kum, Chenevix-Trench, Georgia, Simpson, Peter T. and Lakhani, Sunil R. (2012). Role of HER3 in brain metastases from primary breast cancer. 24th Lorne Cancer Conference, Lorne, VIC, Australia, 9-12 February 2012.

  • Uncovering molecular mechanisms involved in metastasis to the brain

    Saunus, Jodi M., Momeny, Majid, Da Silva, Leonard, Vargas, Ana Cristina, Al-Ejeh, Fares, Morrison, Brian, Khanna, Kum Kum, Grimmond, Sean, Chenevix-Trench, Georgia, Jeffree, Rosalind L., Waddell, Nicola, Simpson, Peter T. and Lakhani, Sunil R. (2012). Uncovering molecular mechanisms involved in metastasis to the brain. 14th International Biennial Congress of the Metastasis Research Society, Brisbane, QLD, Australia, 2-5 September 2012.

  • Calcium Channel Transient Receptor Potential V6 (TRPV6) in Breast Cancer Cell Lines and in Breast Tumours

    Peters Amelia A., Simpson, Peter T., Bassett ,John J., Da Silva Leo, Reid, Lynne, Lakhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2011). Calcium Channel Transient Receptor Potential V6 (TRPV6) in Breast Cancer Cell Lines and in Breast Tumours. 5th PacRim Breast and Prostate Cancer Meeting, Kingscliffe, NSW, Australia, 3-7 May 2011.

  • Expression of the calcium pump PMCA2 in lactating breast and breast cancer

    Lee, W. C., Reid, L., Smart, Chanel, Simpson, P. T., Da Silva, L., Peters, Amelia, Lakhani, Sunil, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2011). Expression of the calcium pump PMCA2 in lactating breast and breast cancer. ComBio 2011, Cairns, Australia, 25-29 September 2011.

  • The Role of Type XI and Type XVII Collagen in Breast Cancer Progression

    Vargas, Ana Cristina, Simpson, Peter, McCart Reed, Amy, Lane, Annette, Smart, Chanel, Da Silva, Leonard and Lakhani, Sunil (2011). The Role of Type XI and Type XVII Collagen in Breast Cancer Progression. 100th Annual Meeting of the United States and Canadian Academy of Pathology, San Antonio, Texas, United States, February 6 - March 4 2011. London, United Kingdom: Nature Publishing Group.

  • The Transient Receptor Potential V6 (TRPV6) channel in clinical breast cancers and breast cancer cell lines

    Peters, Amelia A., Simpson, Peter T., Bassett, John J., Da Silva, Leo, Reid, Lynne, Lakhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory, R. (2011). The Transient Receptor Potential V6 (TRPV6) channel in clinical breast cancers and breast cancer cell lines. 17th International Symposium on Calcium-Binding Proteins and Calcium Function in Health and Disease (CaBP17), Beijing, China, 16-21 July 2011.

  • The role of Type XI Collagen in Breast Cancer Progression

    Vargas, Ana Cristina, Simpson, Peter T., McCart Reed, Amy E., Smart, Chanel, Waddell, Nic, Lane, Annette and Lakhani, Sunil (2011). The role of Type XI Collagen in Breast Cancer Progression. LICR Translational Oncology Conference, Melbourne, Australia, 24-26 October 2011.

  • The transient receptor potential V6 (TRPV6) calcium channel in breast cancer cell lines and clinical breast cancer tissues

    Peters, Amelia, Simpson, Peter T., Bassett, Johnathon, Lakhani, Sunil, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2011). The transient receptor potential V6 (TRPV6) calcium channel in breast cancer cell lines and clinical breast cancer tissues. American Association for Cancer Research 102nd Annual Meeting, Orlando, United States, 2 - 6 April 2011. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2011-2954

  • Lynch syndrome-associated breast cancers: clinicopathological characteristics of a case series from the Colon CFR

    Rosty, Christophe, Walsh, Michael, Cummings, Margaret, Buchanan, Daniel, Arnold, Sven, McKeone, Diane, Walters, Rhiannon, Hopper, John, Jenkins, Mark, Spurdle, Amanda, McGuckin, Michael, Lakhani, Sunil and Young, Joanne (2010). Lynch syndrome-associated breast cancers: clinicopathological characteristics of a case series from the Colon CFR. AACR 101st Annual Meeting 2010, Washington, DC, United States, 17-21 April 2010. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM10-32

  • Distinct pathological characteristics of lobular carcinoma

    Lakhani, SR and Simpson, PT (2010). Distinct pathological characteristics of lobular carcinoma. European Breast Cancer Conference, Barcelona Spain, Mar 24, 2010. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/S1359-6349(10)70242-1

  • Role of breast screening for characterising the heterogeneity of invasive lobular carcinomas of the breast

    Vargas, A. C., Simpson, P., Jayanthan, J., Lane, A., Reid, L., Evans, E., Porter, A. and Lakhani, S. (2010). Role of breast screening for characterising the heterogeneity of invasive lobular carcinomas of the breast. 28th International Congress of the International-Academy-of-Pathology, Sao Paulo, Brazil, 10-15 October 2010. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.

  • Shifting phenotypes in primary human mammary epithelial culture

    Smart, Chanel E., Saunus, Jodi M., Keith, Patricia, Vargas, Ana Cristina, Malik, Neelam, Clarke, Catherine, Simpson, Peter T. and Lakhani, Sunil R. (2010). Shifting phenotypes in primary human mammary epithelial culture. Sixth International Conference on Hormonal Oncogenesis, Tokyo, Japan, 12-16 September 2010.

  • Is there molecular evidence for progression of microglandular adenosis to carcinoma: Results of comparative genomic hybridization (CGH) on microdissected lesions

    Shin, S. J., Simpson, P. T., Da Silva, L., Mahalinga-Iyer, J., Lakhani, S. R. and Rosen, P. P. (2008). Is there molecular evidence for progression of microglandular adenosis to carcinoma: Results of comparative genomic hybridization (CGH) on microdissected lesions. 97th Annual Meeting of the United States and Canadian Academy of Pathology, Denver, CO, United States, 1-7 March 2008. Nature Publishing Group.

  • Evidence of evolution and intrinsic molecular relationship in a spectrum of morphological variants of invasive lobular carcinoma with variable E-cadherin status

    Da Silva, L., Parry, S., Keith, P., Lakhani, S. R. and Simpson, P. (2007). Evidence of evolution and intrinsic molecular relationship in a spectrum of morphological variants of invasive lobular carcinoma with variable E-cadherin status. United States and Canadian Academy of Pathology 2007 Annual Meeting, San Diego, California, 24-30 March, 2007. Baltimore, MD: Nature Publishing.

  • Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

    Smart, C. E., Clarke, C., Brooks, K. M., Raghavendra, A., Brewster, B. L., French, J. D., Hetherington, R., Fleming, J. S., Rothnagel, J. A., Wainwright, B., Lakhani, S. R. and Brown, M. A. (2007). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. Australian Breast Cancer Conference, Melbourne, Australia, 2007.

  • Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

    Brewster, Brooke, Brooke, Kelly, Brown, Melissa Anne, Clarke, C., Fleming, J. S., French, J. D., Hetherington, Rehan, Lakhani, Sunil, Raghavendra, Ashwini, Rothnagel, Joseph, Smart, Chanel and Wainwright, Brandon (2007). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. kConFab Familial Breast Cancer Conference, Couran Cove, Queensland, 21-24 August 2007.

  • Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

    Brewster, Brooke, Brooks, Kelly, Brown, Melissa Anne, Clarke, C., Fleming, J. S., French, J. D., Hetherington, Rehan, Lakhani, Sunil, Raghavendra, Ashwini, Rothnagel, Joseph, Smart, Chanel and Wainwright, Brandon (2007). Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia. Gordon Research Conference: Mammary Gland Biology, Newport, RI, 10-15 June 2007.

  • EGFR amplification and lack of activating mutations in metaplastic breast carcinomas

    Reis, JS, Pinheiro, C, Lambros, MBK, Milanezi, F, Carvalho, S, Savage, K, Simpson, PT, Jones, C, Swift, S, Mackay, A, Reis, RM, Hornick, JL, Pereira, EM, Baltazar, F, Fletcher, CDM, Ashworth, A, Lakhani, SR and Schmitt, FC (2006). EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. 190th Meeting of the Pathological-Society-of-Great-Britain-and-Ireland, Manchester England, Jul 04-07, 2006.

  • Genetic and immunohistopathological evaluation of BRCA1 and BRCA2 unclassified variants

    Chenevix-Trench, G., Healey, S. C., Lakhani, S., Brinkworth, R. I., KConFab, K. C. F., Marsh, A., Brown, M. A., Easton, D. F., Tavtigian, S., Goldgar, D. E. and Spurdle, A. B. (2005). Genetic and immunohistopathological evaluation of BRCA1 and BRCA2 unclassified variants. Familial Cancer 2005: Research and Practice, Couran Cove, Queensland, 30 August - 3 September, 2005.

  • Is there a benign to malignant progression?

    Lakhani, S. R. (1997). Is there a benign to malignant progression?. 2nd International Meeting on Current Topics in Breast Cancer Research, Cambridge, England, Sep, 1996. Bristol, United Kingdom: BioScientifica.

Other Outputs

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

Completed Supervision

This staff member is a UQ Expert for media in the following fields:

Genetics - breast cancer, Breast cancer - family history, Breast cancer, Cancer - breast, Myoepithelial cells, Brain metastasis

They are happy to lend their expertise to your articles or broadcasts and share their research discoveries and insights with the community via media channels.

For additional assistance with story ideas, general advice and information or help with seeking further experts, please email the UQ Media Team or telephone (07) 3365 1120.

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ResearcherID: I-1970-2018

ORCID: 0000-0003-4067-2760

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