The University of Queensland

Iron and liver disease

Crawford, Darrell H. G., Fletcher, Linda M. and Kowdley, Kris V. (2012). Iron and liver disease. Iron physiology and pathophysiology in humans. (pp. 441-445) edited by Gregory J. Anderson and Gordon D. McLaren. New York, United States: Humana Press. doi: 10.1007/978-1-60327-485-2_22

Molecular epidemiology of hepatitis B among Indigenous Australians in Queensland and the Torres Strait Islands

Littlejohn, Margaret, Jaskowski, Lesley-Anne, Edwards, Ros, Jackson, Kathy, Yuen, Lilly, Crawford, Darrel, Locarnini, Stephen A. and Cooksley, Graham (2024). Molecular epidemiology of hepatitis B among Indigenous Australians in Queensland and the Torres Strait Islands. Internal Medicine Journal, 54 (1), 129-138. doi: 10.1111/imj.16166

A salivary biomarker panel to detect liver cirrhosis

Trevisan França de Lima, Lucas, Crawford, Darrell H. G., Broszczak, Daniel A., Zhang, Xi, Bridle, Kim R. and Punyadeera, Chamindie (2023). A salivary biomarker panel to detect liver cirrhosis. iScience, 26 (7) 107015, 107015. doi: 10.1016/j.isci.2023.107015

The impact of posttraumatic stress disorder on upper gastrointestinal investigations in Australian Defence Force veterans: a retrospective review

Crawford, Darrell H. G., Mellor, Rebecca, Duenow, Patrick and Connelly, Luke B. (2023). The impact of posttraumatic stress disorder on upper gastrointestinal investigations in Australian Defence Force veterans: a retrospective review. Internal Medicine Journal, 53 (5), 841-844. doi: 10.1111/imj.16088

Clinical practice guidelines on hemochromatosis: Asian Pacific Association for the Study of the Liver

Crawford, Darrell H. G., Ramm, Grant A., Bridle, Kim R., Nicoll, Amanda J., Delatycki, Martin B. and Olynyk, John K. (2023). Clinical practice guidelines on hemochromatosis: Asian Pacific Association for the Study of the Liver. Hepatology International, 17 (3), 522-541. doi: 10.1007/s12072-023-10510-3

Remembering Lawrie Powell 1934-2022

Farrell, Geoff, Crawford, Darrell and Anderson, Greg (2022). Remembering Lawrie Powell 1934-2022. Journal of Gastroenterology and Hepatology, 37 (11), 2193-2194. doi: 10.1111/jgh.16031

Efficacy and safety of immune-modulating therapy for primary sclerosing cholangitis: a systematic review and meta-analysis

Liu, Xin, Wang, Haolu, Liu, Xinyao, Bridle, Kim, Crawford, Darrell and Liang, Xiaowen (2022). Efficacy and safety of immune-modulating therapy for primary sclerosing cholangitis: a systematic review and meta-analysis. Pharmacology and Therapeutics, 237 108163, 1-13. doi: 10.1016/j.pharmthera.2022.108163

Polypharmacy in Australian veterans with post-traumatic stress disorder upon admission to a mental health facility: A retrospective chart review

Mellor, Rebecca, Khoo, Andrew, Saunders-Dow, Elise, Raguz, Ella, Taing, Meng-Wong, Hanjani, Leila Shafiee, Freeman, Chris and Crawford, Darrell (2022). Polypharmacy in Australian veterans with post-traumatic stress disorder upon admission to a mental health facility: A retrospective chart review. Drugs - Real World Outcomes, 9 (3), 347-357. doi: 10.1007/s40801-022-00298-3

Post‐traumatic stress disorder is associated with a higher rate of polypectomy independent of an increased frequency of colonoscopy in Australian veterans – a retrospective review

Crawford, Darrell H.G., Mellor, Rebecca, Teo, Andrew, Duenow, Patrick and Connelly, Luke B (2022). Post‐traumatic stress disorder is associated with a higher rate of polypectomy independent of an increased frequency of colonoscopy in Australian veterans – a retrospective review. Internal Medicine Journal, 53 (8), 1423-1428. doi: 10.1111/imj.15818

Long-term survival and postoperative complications of pre-liver transplantation transarterial chemoembolisation in hepatocellular carcinoma: a systematic review and meta-analysis

Butcher, Daniel A., Brandis, Kelli J., Wang, Haolu, Spannenburg, Liam, Bridle, Kim R., Crawford, Darrell HG. and Liang, Xiaowen (2022). Long-term survival and postoperative complications of pre-liver transplantation transarterial chemoembolisation in hepatocellular carcinoma: a systematic review and meta-analysis. European Journal of Surgical Oncology, 48 (3), 621-631. doi: 10.1016/j.ejso.2021.09.017

APASL clinical practice guidance: the diagnosis and management of patients with primary biliary cholangitis

You, Hong, Ma, Xiong, Efe, Cumali, Wang, Guiqiang, Jeong, Sook-Hyang, Abe, Kazumichi, Duan, Weijia, Chen, Sha, Kong, Yuanyuan, Zhang, Dong, Wei, Lai, Wang, Fu-Sheng, Lin, Han-Chieh, Yang, Jin Mo, Tanwandee, Tawesak, Gani, Rino A., Payawal, Diana A., Sharma, Barjesh C., Hou, Jinlin, Yokosuka, Osamu, Dokmeci, A. Kadir, Crawford, Darrell, Kao, Jia-Horng, Piratvisuth, Teerha, Suh, Dong Jin, Lesmana, Laurentius A., Sollano, Jose, Lau, George, Sarin, Shiv K. ... Jia, Jidong (2022). APASL clinical practice guidance: the diagnosis and management of patients with primary biliary cholangitis. Hepatology International, 16 (1), 1-23. doi: 10.1007/s12072-021-10276-6

CD73 and PD-L1 as potential therapeutic targets in gallbladder cancer

Cao, Lu, Bridle, Kim R., Shrestha, Ritu, Prithviraj, Prashanth, Crawford, Darrell H. G. and Jayachandran, Aparna (2022). CD73 and PD-L1 as potential therapeutic targets in gallbladder cancer. International Journal of Molecular Sciences, 23 (3) 1565, 1565. doi: 10.3390/ijms23031565

Investigation of C reactive Protein and AIM2 Methylation as a marker for PTSD in Australian Vietnam veterans

McD Young, Ross, Lawford, Bruce, Mellor, Rebecca, Morris, Charles P, Voisey, Joanne, on behalf of the PTSD Initiative, McLeay, Sarah, Harvey, Wendy, Romaniuk, Madeline, Crawford, Darrell, Colquhoun, David, McD Young, Ross, Dwyer, Miriam, Gibson, John, O'Sullivan, Robyn, Cooksley, Graham, Strakosch, Christopher, Thomson, Rachel, Voisey, Joanne and Lawford, Bruce (2021). Investigation of C reactive Protein and AIM2 Methylation as a marker for PTSD in Australian Vietnam veterans. Gene, 803 145898, 1-6. doi: 10.1016/j.gene.2021.145898

Gene expression analysis in three posttraumatic stress disorder cohorts implicates inflammation and innate immunity pathways and uncovers shared genetic risk with major depressive disorder

Garrett, Melanie E., Qin, Xue Jun, Mehta, Divya, Dennis, Michelle F., Marx, Christine E., Grant, Gerald A., Stein, Murray B., Kimbrel, Nathan A., Beckham, Jean C., Hauser, Michael A., Ashley-Koch, Allison E., Brancu, Mira, Calhoun, Patrick S., Dedert, Eric, Elbogen, Eric B., Fairbank, John A., Hurley, Robin A., Kilts, Jason D., Kirby, Angela, Martindale, Sara, McDonald, Scott D., Moore, Scott D., Morey, Rajendra A., Naylor, Jennifer C., Rowland, Jared, Shura, Robert, Swinkels, Cindy, Szabo, Steven T., Taber, Katherine H. ... Lawford, Bruce (2021). Gene expression analysis in three posttraumatic stress disorder cohorts implicates inflammation and innate immunity pathways and uncovers shared genetic risk with major depressive disorder. Frontiers in Neuroscience, 15 678548. doi: 10.3389/fnins.2021.678548

Iron depletion attenuates steatosis in a mouse model of non-alcoholic fatty liver disease: Role of iron-dependent pathways

Crawford, Darrell H.G., Ross, Diana G.F., Jaskowski, Lesley-Anne, Burke, Leslie J., Britton, Laurence J., Musgrave, Nick, Briskey, David, Rishi, Gautam, Bridle, Kim R. and Subramaniam, V. Nathan (2021). Iron depletion attenuates steatosis in a mouse model of non-alcoholic fatty liver disease: Role of iron-dependent pathways. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1867 (7) 166142, 166142. doi: 10.1016/j.bbadis.2021.166142

Liver organoid as a 3D in vitro model for drug validation and toxicity assessment

Brooks, Anastasia, Liang, Xiaowen, Zhang, Yonglong, Zhao, Chun-Xia, Roberts, Michael S., Wang, Haolu, Zhang, Lei and Crawford, Darrell H.G. (2021). Liver organoid as a 3D in vitro model for drug validation and toxicity assessment. Pharmacological Research, 169 105608, 105608. doi: 10.1016/j.phrs.2021.105608

Self-reported Liver Disorders in Australian Vietnam War Veterans

Wang, H., Liang, X., Bridle, K. and Crawford, D. (2021). Self-reported Liver Disorders in Australian Vietnam War Veterans. Journal of Military and Veterans Health, 29 (3), 43-51.

Dual targeting of sorafenib-resistant HCC-derived cancer stem cells

Shrestha, Ritu, Bridle, Kim R., Cao, Lu, Crawford, Darrell H. G. and Jayachandran, Aparna (2021). Dual targeting of sorafenib-resistant HCC-derived cancer stem cells. Current Oncology, 28 (3), 2150-2172. doi: 10.3390/curroncol28030200

Australian recommendations for the management of hepatocellular carcinoma: a consensus statement

Lubel, John S., Roberts, Stuart K., Strasser, Simone I., Thompson, Alexander J., Philip, Jennifer, Goodwin, Mark, Clarke, Stephen, Crawford, Darrell H. G., Levy, Miriam T. and Shackel, Nick (2021). Australian recommendations for the management of hepatocellular carcinoma: a consensus statement. Medical Journal of Australia, 214 (10), 475-483. doi: 10.5694/mja2.50885

Prognostic role of immune checkpoint regulators in cholangiocarcinoma: a pilot study

Cao, Lu, Prithviraj, Prashanth, Shrestha, Ritu, Sharma, Revati, Anaka, Matthew, Bridle, Kim R., Kannourakis, George, Crawford, Darrell H.G. and Jayachandran, Aparna (2021). Prognostic role of immune checkpoint regulators in cholangiocarcinoma: a pilot study. Journal of Clinical Medicine, 10 (10) 2191, 2191. doi: 10.3390/jcm10102191

Combined inhibition of TGF-β1-induced EMT and PD-L1 silencing re-sensitizes hepatocellular carcinoma to sorafenib treatment

Shrestha, Ritu, Prithviraj, Prashanth, Bridle, Kim R., Crawford, Darrell H. G. and Jayachandran, Aparna (2021). Combined inhibition of TGF-β1-induced EMT and PD-L1 silencing re-sensitizes hepatocellular carcinoma to sorafenib treatment. Journal of Clinical Medicine, 10 (9) 1889, 1889. doi: 10.3390/jcm10091889

Reply

Reiling, Janske, Butler, Nick, Simpson, Andrew H., Hodgkinson, Peter, Campbell, Catherine, Lockwood, David, Bridle, Kim J., Santrampurwala, Nishreen, Britton, Laurence J., Crawford, Darrell H., Dejong, Cornelius H. C. and Fawcett, Jonathan (2021). Reply. Liver Transplantation, 27 (4), 602-603. doi: 10.1002/lt.25894

Inhibition of MLKL attenuates necroptotic cell death in a murine cell model of ischaemia injury

Baidya, Raji, Gautheron, Jérémie, Crawford, Darrell H. G., Wang, Haolu and Bridle, Kim R. (2021). Inhibition of MLKL attenuates necroptotic cell death in a murine cell model of ischaemia injury. Journal of Clinical Medicine, 10 (2) 212, 1-18. doi: 10.3390/jcm10020212

Immune checkpoint molecules are regulated by transforming growth factor (Tgf)-β1-induced epithelial-to-mesenchymal transition in hepatocellular carcinoma

Shrestha, Ritu, Bridle, Kim R., Crawford, Darrell H. G. and Jayachandran, Aparna (2021). Immune checkpoint molecules are regulated by transforming growth factor (Tgf)-β1-induced epithelial-to-mesenchymal transition in hepatocellular carcinoma. International Journal of Medical Sciences, 18 (12), 2466-2479. doi: 10.7150/ijms.54239

Assessment and transplantation of orphan donor livers: a back-to-base approach to normothermic machine perfusion

Reiling, Janske, Butler, Nick, Simpson, Andrew, Hodgkinson, Peter, Campbell, Catherine, Lockwood, David, Bridle, Kim, Santrampurwala, Nishreen, Britton, Laurence, Crawford, Darrell, Dejong, Cornelius H. C. and Fawcett, Jonathan (2020). Assessment and transplantation of orphan donor livers: a back-to-base approach to normothermic machine perfusion. Liver Transplantation, 26 (12), 1618-1628. doi: 10.1002/lt.25850

The use of minimally invasive biomarkers for the diagnosis and prognosis of hepatocellular carcinoma

Trevisan França de Lima, Lucas, Broszczak, Daniel, Zhang, Xi, Bridle, Kim, Crawford, Darrell and Punyadeera, Chamindie (2020). The use of minimally invasive biomarkers for the diagnosis and prognosis of hepatocellular carcinoma. Biochimica et Biophysica Acta - Reviews on Cancer, 1874 (2) 188451, 188451. doi: 10.1016/j.bbcan.2020.188451

Necroptosis in hepatosteatotic ischaemia-reperfusion injury

Baidya, Raji, Crawford, Darrell H. G., Gautheron, Jérémie, Wang, Haolu and Bridle, Kim R. (2020). Necroptosis in hepatosteatotic ischaemia-reperfusion injury. International Journal of Molecular Sciences, 21 (16) 5931, 1-29. doi: 10.3390/ijms21165931

Factor structure of posttraumatic stress disorder (PTSD) in Australian Vietnam Veterans: Confirmatory factor analysis of the Clinician-Administered PTSD Scale for DSM–5

Gilmour, John, Romaniuk, Madeline, on behalf of the PTSD Initiative , McLeay, Sarah, Harvey, Wendy, Crawford, Darrell, Colquhoun, David, McD Young, Ross, Dwyer, Miriam, Gibson, John, O’Sullivan, Robyn, Cooksley, Graham, Strakosch, Christopher, Thomson, Rachel, Voisey, Joanne and Lawford, Bruce (2020). Factor structure of posttraumatic stress disorder (PTSD) in Australian Vietnam Veterans: Confirmatory factor analysis of the Clinician-Administered PTSD Scale for DSM–5. Journal of Military, Veteran and Family Health, 6 (1), 48-57. doi: 10.3138/jmvfh-2018-0042

TNF-α-mediated epithelial-to-mesenchymal transition regulates expression of immune checkpoint molecules in hepatocellular carcinoma

Shrestha, Ritu, Bridle, Kim R., Crawford, Darrell H.G. and Jayachandran, Aparna (2020). TNF-α-mediated epithelial-to-mesenchymal transition regulates expression of immune checkpoint molecules in hepatocellular carcinoma. Molecular Medicine Reports, 21 (4), 1849-1860. doi: 10.3892/mmr.2020.10991

Association between hereditary hemochromatosis and hepatocellular carcinoma: a comprehensive review

Jayachandran, Aparna, Shrestha, Ritu, Bridle, Kim R. and Crawford, Darrell H. G. (2020). Association between hereditary hemochromatosis and hepatocellular carcinoma: a comprehensive review. Hepatoma Research, 6 8. doi: 10.20517/2394-5079.2019.35

Therapeutic modulators of hepatic stellate cells for hepatocellular carcinoma

Ruan, Qi, Wang, Haolu, Burke, Leslie J., Bridle, Kim R., Li, Xinxing, Zhao, Chun-Xia, Crawford, Darrell H. G., Roberts, Michael S. and Liang, Xiaowen (2020). Therapeutic modulators of hepatic stellate cells for hepatocellular carcinoma. International Journal of Cancer, 147 (6) ijc.32899, 1519-1527. doi: 10.1002/ijc.32899

Imaging-based vascular-related biomarkers for early detection of acetaminophen-induced liver injury

Wang, Haolu, Burke, Leslie J., Patel, Jatin, Tse, Brian W.C., Bridle, Kim R., Cogger, Victoria C., Li, Xinxing, Liu, Xin, Yang, Haotian, Crawford, Darrell H. G., Roberts, Michael S., Gao, Wenchao and Liang, Xiaowen (2020). Imaging-based vascular-related biomarkers for early detection of acetaminophen-induced liver injury. Theranostics, 10 (15), 6715-6727. doi: 10.7150/thno.44900

APASL HCV guidelines of virus-eradicated patients by DAA on how to monitor HCC occurrence and HBV reactivation

Kanda, Tatsuo, Lau, George K. K., Wei, Lai, Moriyama, Mitsuhiko, Yu, Ming-Lung, Chuang, Wang-Long, Ibrahim, Alaaeldin, Lesmana, Cosmas Rinaldi Adithya, Sollano, Jose, Kumar, Manoj, Jindal, Ankur, Sharma, Barjesh Chander, Hamid, Saeed S., Kadir Dokmeci, A., Mamun-Al-Mahtab,, McCaughan, Geoffrey W., Wasim, Jafri, Crawford, Darrell H. G., Kao, Jia-Horng, Ooka, Yoshihiko, Yokosuka, Osamu, Sarin, Shiv Kumar and Omata, Masao (2019). APASL HCV guidelines of virus-eradicated patients by DAA on how to monitor HCC occurrence and HBV reactivation. Hepatology International, 13 (6), 649-661. doi: 10.1007/s12072-019-09988-7

Immune checkpoint blockade therapies for HCC: current status and future implications

Shrestha, Ritu, Bridle, Kim R., Crawford, Darrell H. G. and Jayachandran, Aparna (2019). Immune checkpoint blockade therapies for HCC: current status and future implications. Hepatoma Research, 2019 (5) 32. doi: 10.20517/2394-5079.2019.24

DNA methylation from germline cells in veterans with PTSD

Mehta, Divya, Pelzer, Elise S., Bruenig, Dagmar, Lawford, Bruce, McLeay, Sarah, Morris, Charles P., Gibson, John N., Young, Ross McD., Voisey, Joanne, Harvey, Wendy, Romaniuk, Madeline, Crawford, Darrell, Colquhoun, David, Dwyer, Miriam, Gibson, John, O'Sullivan, Robyn, Cooksley, Graham, Strakosch, Christopher and Thomson, Rachel (2019). DNA methylation from germline cells in veterans with PTSD. Journal of Psychiatric Research, 116, 42-50. doi: 10.1016/j.jpsychires.2019.06.001

Comparison of sleep patterns in Vietnam veterans with and without posttraumatic stress disorder using wrist actigraphy

Theal, Rebecca, McLeay, Sarah, Gleeson, Sarah, Lowrie, Fraser, O'Sullivan, Robyn, on behalf of the PTSD Initiative, Harvey, Wendy, Romaniuk, Madeline, Crawford, Darrell, Colquhoun, David, Young, Ross McD, Dwyer, Miriam, Gibson, John, Cooksley, Graham, Strakosch, Christopher, Thomson, Rachel, Voisey, Joanne and Lawford, Bruce (2019). Comparison of sleep patterns in Vietnam veterans with and without posttraumatic stress disorder using wrist actigraphy. Journal of Clinical Sleep Medicine, 15 (5), 725-732. doi: 10.5664/jcsm.7762

Interleukin-33 / Cyclin D1 imbalance in severe liver steatosis predicts susceptibility to ischemia reperfusion injury

Núñez, Kelley G., Frank, Anderson, Gonzalez-Rosario, Janet, Galliano, Gretchen, Bridle, Kim, Crawford, Darrell, Seal, John, Abbruscato, Frank, Vashistha, Himanshu, Thevenot, Paul T. and Cohen, Ari J. (2019). Interleukin-33 / Cyclin D1 imbalance in severe liver steatosis predicts susceptibility to ischemia reperfusion injury. PLoS One, 14 (4) e0216242, e0216242. doi: 10.1371/journal.pone.0216242

Resilience and psychopathology in trauma-exposed Australian Veterans: an exploratory factor analysis of the Connor-Davidson Resilience Scale

Kidd, Chloe, Romaniuk, Madeline, McLeay, Sarah, Harvey, Wendy, Romaniuk, Madeline, Crawford, Darrell, Colquhoun, David, McD Young, Ross, Dwyer, Miriam, Gibson, John, O’Sullivan, Robyn, Cooksley, Graham, Strakosch, Christopher, Thomson, Rachel, Voisey, Joanne and Lawford, Bruce (2019). Resilience and psychopathology in trauma-exposed Australian Veterans: an exploratory factor analysis of the Connor-Davidson Resilience Scale. Journal of Military, Veteran and Family Health, 5 (1), 27-39. doi: 10.3138/jmvfh.2018-0016

APASL clinical practice recommendation: how to treat HCV-infected patients with renal impairment?

Kanda, Tatsuo, Lau, George K. K., Wei, Lai, Moriyama, Mitsuhiko, Yu, Ming-Lung, Chuang, Wang-Long, Ibrahim, Alaaeldin, Lesmana, Cosmas Rinaldi Adithya, Sollano, Jose, Kumar, Manoj, Jindal, Ankur, Sharma, Barjesh Chander, Hamid, Saeed S., Dokmeci, A. Kadir, Mamun-Al-Mahtab,, McCaughan, Geofferey W., Wasim, Jafri, Crawford, Darrell H. G., Kao, Jia-Horng, Yokosuka, Osamu, Sarin, Shiv Kumar and Omata, Masao (2019). APASL clinical practice recommendation: how to treat HCV-infected patients with renal impairment?. Hepatology International, 13 (2), 103-109. doi: 10.1007/s12072-018-9915-5

Five‐year conditional survival for patients with hepatocellular carcinoma in Queensland, Australia

Valery, Patricia C., Baade, Peter A., Stuart, Katherine A., Leggett, Barbara A., Macdonald, Graeme A., Whiteman, David C., Crawford, Darrell H. and Clark, Paul J. (2019). Five‐year conditional survival for patients with hepatocellular carcinoma in Queensland, Australia. GastroHep, 1 (2), 61-69. doi: 10.1002/ygh2.327

Spotlight on Bortezomib: potential in the treatment of hepatocellular carcinoma

Huang, I-Tao, Dhungel, Bijay, Shrestha, Ritu, Bridle, Kim R., Crawford, Darrell H. G., Jayachandran, Aparna and Steel, Jason C (2019). Spotlight on Bortezomib: potential in the treatment of hepatocellular carcinoma. Expert Opinion on Investigational Drugs, 28 (1), 7-18. doi: 10.1080/13543784.2019.1551359

Exosome-based liquid biopsy in the management of hepatocellular carcinoma

Jayachandran, Aparna, Manda, Sasidhar Venkata, Shrestha, Ritu, Bridle, Kim R., Prithviraj, Prashanth and Crawford, Darrell H. G. (2018). Exosome-based liquid biopsy in the management of hepatocellular carcinoma. Hepatoma Research, 4 (8) 44, 44. doi: 10.20517/2394-5079.2018.59

Monitoring immune checkpoint regulators as predictive biomarkers in hepatocellular carcinoma

Shrestha, Ritu, Prithviraj, Prashanth, Anaka, Matthew, Bridle, Kim R., Crawford, Darrell H. G., Dhungel, Bijay, Steel, Jason C. and Jayachandran, Aparna (2018). Monitoring immune checkpoint regulators as predictive biomarkers in hepatocellular carcinoma. Frontiers in Oncology, 8 (JUL) 269, 269. doi: 10.3389/fonc.2018.00269

Hepatic iron concentration correlates with insulin sensitivity in nonalcoholic fatty liver disease

Britton, Laurence, Bridle, Kim, Reiling, Janske, Santrampurwala, Nishreen, Wockner, Leesa, Ching, Helena, Stuart, Katherine, Subramaniam, V Nathan, Jeffrey, Gary, St Pierre, Tim, House, Michael, Gummer, Joel, Trengove, Robert, Olynyk, John, Crawford, Darrell and Adams, Leon (2018). Hepatic iron concentration correlates with insulin sensitivity in nonalcoholic fatty liver disease. Hepatology Communications, 2 (6), 644-653. doi: 10.1002/hep4.1190

Sleep disturbances in Australian Vietnam veterans with and without posttraumatic stress disorder

Baird, Timothy, McLeay, Sarah, Harvey, Wendy, Theal, Rebecca, Law, Dayna, Romaniuk, Madeline, Crawford, Darrell, Colquhoun, David, Young, Ross, Dwyer, Miriam, Gibson, John, O'Sullivan, Robyn, Cooksley, Graham, Strakosch, Christopher, Thomson, Rachel, Voisey, Joanne and Lawford, Bruce (2018). Sleep disturbances in Australian Vietnam veterans with and without posttraumatic stress disorder. Journal of Clinical Sleep Medicine, 14 (5), 745-752. doi: 10.5664/jcsm.7096

Evaluation of a bone morphogenetic protein 6 variant as a cause of iron loading

McDonald, Cameron J., Rishi, Gautam, Secondes, Eriza S., Ostini, Lesa, Wallace, Daniel F., Crawford, Darrell H. G., Sia, Hanlon, Clark, Paul and Subramaniam, V. Nathan (2018). Evaluation of a bone morphogenetic protein 6 variant as a cause of iron loading. Human Genomics, 12 (1) 23, 23. doi: 10.1186/s40246-018-0155-5

Ferroportin expression in adipocytes does not contribute to iron homeostasis or metabolic responses to a high calorie diet

Britton, Laurence, Jaskowski, Lesley-Anne, Bridle, Kim, Secondes, Eriza, Wallace, Daniel, Santrampurwala, Nishreen, Reiling, Janske, Miller, Gregory, Mangiafico, Salvatore, Andrikopoulos, Sofianos, Subramaniam, V. Nathan and Crawford, Darrell (2018). Ferroportin expression in adipocytes does not contribute to iron homeostasis or metabolic responses to a high calorie diet. CMGH, 5 (3), 319-331. doi: 10.1016/j.jcmgh.2018.01.005

Iron inhibits the secretion of Apolipoprotein E in cultured human adipocytes

Britton, L. J., Bridle, Kim, Jaskowski, Lesley-Anne, He, Jingjing, Ng, Choaping, Ruelcke, Jayde E., Mohamed, Ahmed, Reiling, Janske, Santrampurwala, Nishreen, Hill, Michelle M., Whitehead, Jonathan P., Subramaniam, V. Nathan and Crawford, Darrell H. G. (2018). Iron inhibits the secretion of Apolipoprotein E in cultured human adipocytes. Cellular and Molecular Gastroenterology and Hepatology, 6 (2), 214-217. doi: 10.1016/j.jcmgh.2018.04.005

Concise Review: Quantitative Detection and Modeling the In Vivo Kinetics of Therapeutic Mesenchymal Stem/Stromal Cells

Brooks, Anastasia, Futrega, Kathryn, Liang, Xiaowen, Hu, Xiaoling, Liu, Xin, Crawford, Darrell H. G., Doran, Michael R., Roberts, Michael S. and Wang, Haolu (2017). Concise Review: Quantitative Detection and Modeling the In Vivo Kinetics of Therapeutic Mesenchymal Stem/Stromal Cells. Stem Cells Translational Medicine, 7 (1), 78-86. doi: 10.1002/sctm.17-0209

Reduction of body iron in HFE-related haemochromatosis and moderate iron overload (Mi-Iron): a multicentre, participant-blinded, randomised controlled trial

Ong, Sim Y., Gurrin, Lyle C., Dolling, Lara, Dixon, Jeanette, Nicoll, Amanda J., Wolthuizen, Michelle, Wood, Erica M., Anderson, Gregory J., Ramm, Grant A., Allen, Katrina J., Olynyk, John K., Crawford, Darrell, Ramm, Louise E., Gow, Paul, Durrant, Simon, Powell, Lawrie W. and Delatycki, Martin B. (2017). Reduction of body iron in HFE-related haemochromatosis and moderate iron overload (Mi-Iron): a multicentre, participant-blinded, randomised controlled trial. Lancet Haematology, 4 (12), E607-E614. doi: 10.1016/S2352-3026(17)30214-4

The Implications of the Shift Toward Donation After Circulatory Death in Australia

Reiling, Janske, Forrest, Elizabeth, Bridle, Kim R., Britton, Laurence J., Santrampurwala, Nishreen, Crawford, Darrell H. G., Dejong, Cornelis H. C. and Fawcett, Jonathan (2017). The Implications of the Shift Toward Donation After Circulatory Death in Australia. Transplantation Direct, 3 (12) e226, 1-7. doi: 10.1097/TXD.0000000000000743

Visualization and Modeling of the In Vivo Distribution of Mesenchymal Stem Cells

Wang, Haolu, Thorling, Camilla A., Xu, Zhi Ping, Crawford, Darrell H. G., Liang, Xiaowen, Liu, Xin and Roberts, Michael S. (2017). Visualization and Modeling of the In Vivo Distribution of Mesenchymal Stem Cells. Current Protocols in Stem Cell Biology, 43 (1), 1-17. doi: 10.1002/cpsc.39

The cost of successful antiviral therapy in hepatitis C patients: a comparison of IFN-free versus IFN-based regimens at an individual patient level in Australia

Lee, Allister Sebastian, van Driel, Mieke L. and Crawford, Darrell H (2017). The cost of successful antiviral therapy in hepatitis C patients: a comparison of IFN-free versus IFN-based regimens at an individual patient level in Australia. ClinicoEconomics and Outcomes Research, 9, 595-607. doi: 10.2147/CEOR.S146280

Serum ferritin concentration predicts hepatic fibrosis better than hepatic iron concentration in human HFE-Haemochromatosis

Wood, Marnie J., Crawford, Darrell H. G., Wockner, Leesa F., Powell, Lawrie W. and Ramm, Grant A. (2017). Serum ferritin concentration predicts hepatic fibrosis better than hepatic iron concentration in human HFE-Haemochromatosis. Liver International, 37 (9), 1382-1388. doi: 10.1111/liv.13395

The role of macrophages in the development of biliary injury in a lipopolysaccharide-aggravated hepatic ischaemia-reperfusion model

Reiling, J., Bridle, K. R., Schaap, F. G., Jaskowski, L., Santrampurwala, N., Britton, L. J., Campbell, C. M., Jansen, P. L. M., Damink, S. W. M. O., Crawford, D. H. G., Dejong, C. H. C. and Fawcett, J. (2017). The role of macrophages in the development of biliary injury in a lipopolysaccharide-aggravated hepatic ischaemia-reperfusion model. Biochimica et Biophysica Acta, 1864 (4 Pt B), 1284-1292. doi: 10.1016/j.bbadis.2017.06.028

Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice

Heritage, Mandy, Jaskowski, Lesley, Bridle, Kim, Campbell, Catherine, Briskey, David, Britton, Laurence, Fletcher, Linda, Vitetta, Luis, Subramaniam, V. Nathan and Crawford, Darrell (2017). Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice. World Journal of Gastrointestinal Pathophysiology, 8 (2), 67-76. doi: 10.4291/wjgp.v8.i2.67

Physical comorbidities of post-traumatic stress disorder in Australian Vietnam War veterans

McLeay, Sarah C., Harvey, Wendy M., Romaniuk, Madeline N. M., Crawford, Darrell H. G., Colquhoun, David M., Young, Ross McD., Dwyer, Miriam, Gibson, John M., O'Sullivan, Robyn A., Cooksley, Graham, Strakosch, Christopher R., Thomson, Rachel M., Voisey, Joanne and Lawford, Bruce R. (2017). Physical comorbidities of post-traumatic stress disorder in Australian Vietnam War veterans. Medical Journal of Australia, 206 (6), 251-257. doi: 10.5694/mja16.00935

Time to viral suppression is not related to achievement of SVR12 in HCV GT1-infected patients treated with ombitasvir/paritaprevir/ritonavir and dasabuvir with or without ribavirin

Alqahtani, S., Ozaras, R., Isakov, V., Wyles, D., Ferenci, P., Feld, J. J., Calinas, F., Gschwantler, M., Gane, E., Crawford, D., Jacobson, I. M., Dumas, E. O., King, M. and Sulkowski, M. (2017). Time to viral suppression is not related to achievement of SVR12 in HCV GT1-infected patients treated with ombitasvir/paritaprevir/ritonavir and dasabuvir with or without ribavirin. Journal of Viral Hepatitis, 24 (4), 280-286. doi: 10.1111/jvh.12641

Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury

Wang, Haolu, Zhang, Run, Bridle, Kim R., Jayachandran, Aparna, Thomas, James A., Zhang, Wenzhu, Yuan, Jingli, Xu, Zhi Ping, Crawford, Darrell H. G., Liang, Xiaowen, Liu, Xin and Roberts, Michael S. (2017). Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury. Scientific Reports, 7 (1) 45374, 45374. doi: 10.1038/srep45374

Low-dose lipopolysaccharide causes biliary injury by blood biliary barrier impairment in a rat hepatic ischemia/reperfusion model

Reiling, Janske, Bridle, Kim R., Gijbels, Marion, Schaap, Frank G., Jaskowski, Lesley, Santrampurwala, Nishreen, Britton, Laurence J., Campbell, Catherine M., Olde Damink, Steven W. M., Crawford, Darrell H. G., Dejong, Cornelius H. C. and Fawcett, Jonathan (2017). Low-dose lipopolysaccharide causes biliary injury by blood biliary barrier impairment in a rat hepatic ischemia/reperfusion model. Liver Transplantation, 23 (2), 194-206. doi: 10.1002/lt.24681

Iron and non-alcoholic fatty liver disease

Britton, Laurence J., Subramaniam, V. Nathan and Crawford, Darrell H. G. (2016). Iron and non-alcoholic fatty liver disease. World Journal of Gastroenterology, 22 (36), 8112-8122. doi: 10.3748/wjg.v22.i36.8112

APASL consensus statements and recommendations for hepatitis C prevention, epidemiology, and laboratory testing

Omata, Masao, Kanda, Tatsuo, Wei, Lai, Yu, Ming-Lung, Chuang, Wang-Long, Ibrahim, Alaaeldin, Lesmana, Cosmas Rinaldi Adithya, Sollano, Jose, Kumar, Manoj, Jindal, Ankur, Sharma, Barjesh Chander, Hamid, Saeed S., Dokmeci, A. Kadir, Al-Mahtab, Mamun, McCaughan, Geofferey W., Wasim, Jafri, Crawford, Darrell H. G., Kao, Jia-Horng, Yokosuka, Osamu, Lau, George K. K. and Sarin, Shiv Kumar (2016). APASL consensus statements and recommendations for hepatitis C prevention, epidemiology, and laboratory testing. Hepatology International, 10 (5), 681-701. doi: 10.1007/s12072-016-9736-3

Probiotics modify tight-junction proteins in an animal model of nonalcoholic fatty liver disease

Briskey, David, Heritage, Mandy, Jaskowski, Lesley-Anne, Peake, Jonathan, Gobe, Glenda, Subramaniam, V. Nathan, Crawford, Darrell, Campbell, Catherine and Vitetta, Luis (2016). Probiotics modify tight-junction proteins in an animal model of nonalcoholic fatty liver disease. Therapeutic Advances in Gastroenterology, 9 (4), 463-472. doi: 10.1177/1756283X16645055

Heterozygous Hfe gene deletion leads to impaired glucose homeostasis, but not liver injury in mice fed a high-calorie diet

Britton, Laurence, Jaskowski, Lesley, Bridle, Kim, Santrampurwala, Nishreen, Reiling, Janske, Musgrave, Nick, Subramaniam, V. Nathan and Crawford, Darrell (2016). Heterozygous Hfe gene deletion leads to impaired glucose homeostasis, but not liver injury in mice fed a high-calorie diet. Physiological Reports, 4 (12) e12837, e12837. doi: 10.14814/phy2.12837

Visualizing liver anatomy, physiology and pharmacology using multiphoton microscopy

Wang, Haolu, Liang, Xiaowen, Gravot, Germain, Thorling, Camilla A., Crawford, Darrell H. G., Xu, Zhi Ping, Liu, Xin and Roberts, Michael S. (2016). Visualizing liver anatomy, physiology and pharmacology using multiphoton microscopy. Journal of Biophotonics, 10 (1), 46-60. doi: 10.1002/jbio.201600083

APASL consensus statements and recommendation on treatment of hepatitis C

Omata, Masao, Kanda, Tatsuo, Wei, Lai, Yu, Ming-Lung, Chuang, Wang-Long, Ibrahim, Alaaeldin, Lesmana, Cosmas Rinaldi Adithya, Sollano, Jose, Kumar, Manoj, Jindal, Ankur, Sharma, Barjesh Chander, Hamid, Saeed S., Dokmeci, A. Kadir, Mamun-Al-Mahtab, McCaughan, Geofferey W., Wasim, Jafri, Crawford, Darrell H. G., Kao, Jia-Horng, Yokosuka, Osamu, Lau, George K. K. and Sarin, Shiv Kumar (2016). APASL consensus statements and recommendation on treatment of hepatitis C. Hepatology International, 10 (5), 702-726. doi: 10.1007/s12072-016-9717-6

A physiologically based kinetic model for elucidating the in vivo distribution of administered mesenchymal stem cells

Wang, Haolu, Liang, Xiaowen, Xu, Zhi Ping, Crawford, Darrell H. G, Liu, Xin and Roberts, Michael S. (2016). A physiologically based kinetic model for elucidating the in vivo distribution of administered mesenchymal stem cells. Scientific Reports, 6 (1) 22293, e22293.1-e22293.12. doi: 10.1038/srep22293

Does the death knell toll for phlebotomy in NAFLD? Reply

Adams, Leon A., Crawford, Darrell H., St Pierre, Tim K. and Olynyk, John K. (2015). Does the death knell toll for phlebotomy in NAFLD? Reply. Hepatology, 62 (6), 1921-1922. doi: 10.1002/hep.28030

Should HFE p.C282Y homozygotes with moderately elevated serum ferritin be treated? A randomised controlled trial comparing iron reduction with sham treatment (Mi-iron)

Ong, Sim Yee, Dolling, Lara, Dixon, Jeannette L., Nicoll, Amanda J., Gurrin, Lyle C, Wolthuizen, Michelle, Wood, Erica M., Anderson, Greg J., Ramm, Grant A., Allen, Katrina J., Olynyk J.K., Crawford, Darrell, Kava, Jennifer, Ramm, Louise E., Gow, Paul, Durrant, Simon, Powell, Lawrie W. and Delatycki, Martin B. (2015). Should HFE p.C282Y homozygotes with moderately elevated serum ferritin be treated? A randomised controlled trial comparing iron reduction with sham treatment (Mi-iron). BMJ Open, 5 (8) e008938, e008938. doi: 10.1136/bmjopen-2015-008938

Next-generation sequencing: Application of a novel platform to analyze atypical iron disorders

McDonald, Cameron J., Ostini, Lesa., Wallace, Daniel F., Lyons, Alison., Crawford, Darrell H.G. and Subramaniam, V. Nathan. (2015). Next-generation sequencing: Application of a novel platform to analyze atypical iron disorders. Journal of Hepatology, 63 (5), 1288-1293. doi: 10.1016/j.jhep.2015.06.027

Features of hepatitis C virus infection, current therapies and ongoing clinical trials in ten Asian Pacific countries

Omata, Masao, Kanda, Tatsuo, Yokosuka, Osamu, Crawford, Darrell, Al-Mahtab, Mamun, Wei, Lai, Ibrahim, Alaaeldin, Lau, George K.K, Sharma, Barjesh C, Hamid, Saeed S, Chuang, Wan-Long and Dokmeci, A.Kadir (2015). Features of hepatitis C virus infection, current therapies and ongoing clinical trials in ten Asian Pacific countries. Hepatology International, 9 (4), 486-507. doi: 10.1007/s12072-015-9630-4

The impact of phlebotomy in nonalcoholic fatty liver disease: a prospective, randomized, controlled trial

Adams, Leon A., Crawford, Darrell H., Stuart, Katherine, House, Michael J., St Pierre, Timothy G., Webb, Malcolm, Ching, Helena L. I., Kava, Jenny, Bynevelt, Michael, MacQuillan, Gerry C., Garas, George, Ayonrinde, Oyekoya T., Mori, Trevor A., Croft, Kevin D., Niu, Xianwa, Jeffrey, Gary P. and Olynyk, John K. (2015). The impact of phlebotomy in nonalcoholic fatty liver disease: a prospective, randomized, controlled trial. Hepatology, 61 (5), 1555-1564. doi: 10.1002/hep.27662

Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2-/- mice

Bridle, Kim R., Sobbe, Amy L., de Guzman, C. Erika, Santrampurwala, Nishreen, Jaskowski, Lesley A., Clouston, Andrew D., Campbell, Catherine M., Nathan Subramaniam, V. and Crawford, Darrell H. G. (2015). Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2-/- mice. Liver International, 35 (4), 1451-1463. doi: 10.1111/liv.12494

Urea production during Normothermic Machine Perfusion: Price of Success?

Reiling, Janske, Lockwood, David S. R., Simpson, Andrew H., Campbell, Catherine M., Bridle, Kim R., Santrampurwala, Nishreen, Britton, Laurence J., Crawford, Darrell Henry G., Dejong, Cornelius H. C. and Fawcett, Jonathan (2015). Urea production during Normothermic Machine Perfusion: Price of Success?. Liver Transplantation, 21 (5), 700-703. doi: 10.1002/lt.24094

Inconsistent hepatic antifibrotic effects with the iron chelator deferasirox

Sobbe, Amy, Bridle, Kim R., Jaskowski, Lesley, de Guzman, C. Erika, Santrampurwala, Nishreen, Clouston, Andrew D., Campbell, Catherine M., Subramaniam, V. Nathan and Crawford, Darrell H. G. (2015). Inconsistent hepatic antifibrotic effects with the iron chelator deferasirox. Journal of Gastroenterology and Hepatology, 30 (3), 638-645. doi: 10.1111/jgh.12720

Real-time histology in liver disease using multiphoton microscopy with fluorescence lifetime imaging

Wang, Haolu, Liang, Xiaowen, Mohammed, Yousuf H., Thomas, James A., Bridle, Kim R., Thorling, Camilla A., Grice, Jeffrey E., Xu, Zhi Ping, Liu, Xin, Crawford, Darrell H. G. and Roberts, Michael S. (2015). Real-time histology in liver disease using multiphoton microscopy with fluorescence lifetime imaging. Biomedical Optics Express, 6 (3), 780-792. doi: 10.1364/BOE.6.000780

Diagnostic imaging and therapeutic application of nanoparticles targeting the liver

Wang, Haolu, Thorling, Camilla A., Liang, Xiaowen, Bridle, Kim R., Grice, Jeffrey E., Zhu, Yian, Crawford, Darrell H. G., Xu, Zhi Ping, Liu, Xin and Roberts, Michael S. (2015). Diagnostic imaging and therapeutic application of nanoparticles targeting the liver. Journal of Materials Chemistry B, 3 (6), 939-958. doi: 10.1039/C4TB01611D

Assessing steatotic liver function after ischemia-reperfusion injury by in vivo multiphoton imaging of fluorescein disposition

Thorling C.A., Jin L., Weiss M., Crawford D., Liu X., Burczynski F.J., Liu D., Wang H. and Roberts M.S. (2015). Assessing steatotic liver function after ischemia-reperfusion injury by in vivo multiphoton imaging of fluorescein disposition. Drug Metabolism and Disposition, 43 (1), 154-162. doi: 10.1124/dmd.114.060848

Reimbursement policies in the Asia-Pacific for chronic hepatitis B

Lim, Seng Gee, Amarapurkar, Deepak N., Chan, Henry Lik-Yuen, Crawford, Darrell H., Gane, Edward J., Han, Kwang-Hyub, Ahn, Sang Hoon, Jafri, Wasim, Jia, Jidong, Kao, Jia-Horng, Lesmana, Laurentius A., Lesmana, C. Rinaldi A., Mohamed, Rosmawati, Pham Hoang Phiet,, Piratvisuth, Teerha, Sarin, Shiv K., Sollarno, Jose D., Eguchi, Yuichiro, Mamun-Al Mahtab, and Lee, Keat Hong (2015). Reimbursement policies in the Asia-Pacific for chronic hepatitis B. Hepatology International, 9 (1), 43-51. doi: 10.1007/s12072-014-9593-x

Remoteness, race and social disadvantage: Disparities in hepatocellular carcinoma incidence and survival in Queensland, Australia

Clark, Paul J., Stuart, Katherine A., Leggett, Barbara A., Crawford, Darrell H., Boyd, Peter, Fawcett, Jonathan, Whiteman, David C. and Baade, Peter D. (2015). Remoteness, race and social disadvantage: Disparities in hepatocellular carcinoma incidence and survival in Queensland, Australia. Liver International, 35 (12), 2584-2594. doi: 10.1111/liv.12853

Multiphoton microscopy in defining liver function

Thorling, Camilla A., Crawford, Darrell, Burczynski, Frank J., Liu, Xin, Liau, Ian and Roberts, Michael S. (2014). Multiphoton microscopy in defining liver function. Journal of Biomedical Optics, 19 (9) 090901, 90901-090901. doi: 10.1117/1.JBO.19.9.090901

Interleukin-28B rs12979860 C allele: protective against advanced fibrosis in chronic hepatitis C genotype 1 infection

Kitson, Matthew T., George, Jacob, Dore, Gregory J., Leung, Reynold, Button, Peter, McCaughan, Geoffrey W., Crawford, Darrell H. G., Sievert, William, Weltman, Martin D., Cheng, Wendy S. C. and Roberts, Stuart K. (2014). Interleukin-28B rs12979860 C allele: protective against advanced fibrosis in chronic hepatitis C genotype 1 infection. Journal of Gastroenterology and Hepatology (Australia), 29 (7), 1458-1462. doi: 10.1111/jgh.12544

ITPA genotype protects against anemia during peginterferon and ribavirin therapy but does not influence virological response

Holmes, Jacinta A., Roberts, Stuart K., Ali, Rachel J., Dore, Gregory J., Sievert, William, McCaughan, Geoffrey W., Crawford, Darrell H., Cheng, Wendy S., Weltman, Martin D., Bonanzinga, Sara, Visvanathan, Kumar, Sundararajan, Vijaya, Desmond, Paul V., Bowden, D. Scott, Matthews, Gail V. and Thompson, Alexander J. (2014). ITPA genotype protects against anemia during peginterferon and ribavirin therapy but does not influence virological response. Hepatology, 59 (6), 2152-2160. doi: 10.1002/hep.27022

Effects of long-term hepatic ischemia-reperfusion injury on the function of P-glycoprotein in vivo in rats

Thorling, Camilla A., Roberts, Michael S., Liu, Xin, Fletcher, Linda M., Crawford, Darrell and Burczynski, Frank J. (2014). Effects of long-term hepatic ischemia-reperfusion injury on the function of P-glycoprotein in vivo in rats. Journal of Pharmacy and Pharmaceutical Sciences, 17 (1), 121-135. doi: 10.18433/J33C7B

Distribution of interferon lambda-3 gene polymorphisms in Australian patients with previously untreated genotype 1 chronic hepatitis C: analysis from the PREDICT and CHARIOT studies

Roberts, Stuart K., Mitchell, Joanne, Leung, Reynold, Booth, David, Bollipo, Steven, Ostapowicz, George, Sloss, Andrew, McCaughan, Geoffrey W., Dore, Gregory J., Thompson, Alexander, Crawford, Darrell H. G., Sievert, William, Weltman, Martin, Cheng, Wendy and George, Jacob (2014). Distribution of interferon lambda-3 gene polymorphisms in Australian patients with previously untreated genotype 1 chronic hepatitis C: analysis from the PREDICT and CHARIOT studies. Journal of Gastroenterology and Hepatology (Australia), 29 (1), 179-184. doi: 10.1111/jgh.12424

Hereditary hemochromatosis types 1, 2, and 3

Crawford, Darrell H. G. (2014). Hereditary hemochromatosis types 1, 2, and 3. Clinical Liver Disease, 3 (5), 96-97. doi: 10.1002/cld.339

Intravital multiphoton imaging of the selective uptake of water-dispersible quantum dots into sinusoidal liver cells

Liang X., Grice J.E., Zhu Y., Liu D., Sanchez W.Y., Li Z., Crawford D.H.G., Le Couteur D.G., Cogger V.C., Liu X., Xu Z.P. and Roberts M.S. (2014). Intravital multiphoton imaging of the selective uptake of water-dispersible quantum dots into sinusoidal liver cells. Small, 11 (14), 1711-1720. doi: 10.1002/smll.201402698

Treatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin

Feld, Jordan J., Kowdley, Kris V., Coakley, Eoin, Sigal, Samuel, Nelson, David R., Crawford, Darrell, Weiland, Ola, Aguilar, Humberto, Xiong, Junyuan, Pilot-Matias, Tami, DaSilva-Tillmann, Barbara, Larsen, Lois, Podsadecki, Thomas and Bernstein, Barry (2014). Treatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin. New England Journal of Medicine, 370 (17), 1594-1603. doi: 10.1056/NEJMoa1315722

A corn oil-based diet protects against combined ethanol and iron-induced liver injury in a mouse model of hemochromatosis

Tan, Terrence C. H., Crawford, Darrell H. G., Jaskowski, Lesley A., Murphy, Therese L., Santrampurwala, Nishreen, Crane, Denis, Clouston, Andrew D., Subramaniam, V. Nathan, Anderson, Gregory J. and Fletcher, Linda M. (2013). A corn oil-based diet protects against combined ethanol and iron-induced liver injury in a mouse model of hemochromatosis. Alcoholism-Clinical and Experimental Research, 37 (10), 1619-1631. doi: 10.1111/acer.12155

Iron storage disease in Asia-Pacific populations: the importance of non-HFE mutations

McDonald, Cameron J., Wallace, Daniel F., Crawford, Darrell H. G. and Subramaniam, V. Nathan (2013). Iron storage disease in Asia-Pacific populations: the importance of non-HFE mutations. Journal of Gastroenterology and Hepatology, 28 (7), 1087-1094. doi: 10.1111/jgh.12222

Interaction of serum ferritin and body mass index in patients with chronic hepatitis B: improved prediction of cirrhosis

Paul, Sanjoy, O’Regan, Kevin, St John, Andrew, Stuart, Katherine and Crawford, Darrell (2013). Interaction of serum ferritin and body mass index in patients with chronic hepatitis B: improved prediction of cirrhosis. Hepatology, 57 (5), 2094-2095. doi: 10.1002/hep.26076

Vitamin D status does not predict sustained virologic response or fibrosis stage in chronic hepatitis C genotype 1 infection

Kitson, Matthew T., Dore, Gregory J., George, Jacob, Button, Peter, McCaughan, Geoffrey W., Crawford, Darrell H. G., Sievert, William, Weltman, Martin D., Cheng, Wendy S. and Roberts, Stuart K. (2013). Vitamin D status does not predict sustained virologic response or fibrosis stage in chronic hepatitis C genotype 1 infection. Journal of Hepatology, 58 (3), 467-472. doi: 10.1016/j.jhep.2012.11.017

Excess iron modulates endoplasmic reticulum stress-associated pathways in a mouse model of alcohol and high-fat diet-induced liver injury

Tan, Terrence C. H., Crawford, Darrell H. G., Jaskowski, Lesley A., Subramaniam,V. Nathan, Clouston, Andrew D., Crane, Denis I., Bridle, Kim R., Anderson, Gregory J. and Fletcher, Linda M. (2013). Excess iron modulates endoplasmic reticulum stress-associated pathways in a mouse model of alcohol and high-fat diet-induced liver injury. Laboratory Investigation, 93 (12), 1295-1312. doi: 10.1038/labinvest.2013.121

Elevated serum ferritin: what should GPs know?

Goot, Katie, Hazeldine, Simon, Bentley, Peter, Olynyk, John and Crawford, Darrell (2012). Elevated serum ferritin: what should GPs know?. Australian Family Physician, 41 (12), 945-949.

The serum hepcidin:ferritin ratio is a potential biomarker for cirrhosis

Tan, Terrence C. H., Crawford, Darrell H. G., Franklin, Michael E., Jaskowski, Lesley A., Macdonald, Graeme A., Jonsson, Julie R., Watson, Melanie J., Taylor, Paul J. and Fletcher, Linda M. (2012). The serum hepcidin:ferritin ratio is a potential biomarker for cirrhosis. Liver International, 32 (9), 1391-1399. doi: 10.1111/j.1478-3231.2012.02828.x

Hepatocellular necrosis, fibrosis and microsomal activity determine the hepatic pharmacokinetics of basic drugs in right-heart-failure-induced liver damage

Li, Peng, Robertson, Thomas A., Zhang, Qian, Fletcher, Linda M., Crawford, Darrell H. G., Weiss, Michael and Roberts, Michael S. (2012). Hepatocellular necrosis, fibrosis and microsomal activity determine the hepatic pharmacokinetics of basic drugs in right-heart-failure-induced liver damage. Pharmaceutical Research, 29 (6), 1658-1669. doi: 10.1007/s11095-012-0690-z

Early on-treatment viral load and baseline METAVIR score: improved prediction of sustained virological response in HCV genotype 1 patients

Crawford, Darrell H. G., Dore, Gregory J., Sievert, William, Cheng, Wendy S. C., Weltman, Martin, McCaughan, Geoffrey, Rawlinson, William, Marks, Philippa S., Yoshihara, Motoko, Rizkalla, Bishoy, Roberts, Stuart K. and the CHARIOT Study Group (2012). Early on-treatment viral load and baseline METAVIR score: improved prediction of sustained virological response in HCV genotype 1 patients. Antiviral Therapy, 17 (5), 849-854. doi: 10.3851/IMP2104

Iron predicts tolerance in liver transplantation

Wallace, Daniel F., Crawford, Darrell H. G. and Subramaniam, V. Nathan (2012). Iron predicts tolerance in liver transplantation. Gastroenterology, 143 (3), 862-865. doi: 10.1053/j.gastro.2012.07.091

The control of iron homeostasis: MICRORNAS join the party

Wallace, Daniel F., Crawford, Darrell H.G. and Subramaniam, V. Nathan (2011). The control of iron homeostasis: MICRORNAS join the party. Gastroenterology, 141 (4), 1520-1522. doi: 10.1053/j.gastro.2011.08.018

Testing for HFE-related haemochromatosis

St John, Andrew T., Stuart, Katherine A. and Crawford, Darrell H. G. (2011). Testing for HFE-related haemochromatosis. Australian Prescriber, 34 (3), 73-76. doi: 10.18773/austprescr.2011.046

Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis

Li, Peng, Robertson, Thomas A., Thorling, Camilla A., Zhang, Qian, Fletcher, Linda M., Crawford, Darrell H. G. and Roberts, Michael S. (2011). Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis. Drug Metabolism and Disposition, 39 (4), 571-579. doi: 10.1124/dmd.110.036806

Virological response is associated with decline in hemoglobin concentration during pegylated interferon and ribavirin therapy in hepatitis C virus genotype 1

Sievert, William, Dore, Gregory J., McCaughan, Geoffrey W., Yoshihara, Motoko, Crawford, Darrell H., Cheng, Wendy, Weltman, Martin, Rawlinson, William, Rizkalla, Bishoy, DePamphilis, Jean K., Roberts, Stuart K. and on behalf of the CHARIOT Study Group (2011). Virological response is associated with decline in hemoglobin concentration during pegylated interferon and ribavirin therapy in hepatitis C virus genotype 1. Hepatology, 53 (4), 1109-1117. doi: 10.1002/hep.24180

Altered Lipid Metabolism in Hfe-Knockout Mice Promotes Severe NAFLD and Early Fibrosis

Tan, Terrence C.H., Crawford, Darrell H.G., Jaskowski, Lesley A., Murphy, Therese M., Heritage, Mandy L., Subramaniam, V. Nathan, Clouston, Andrew D., Anderson, Gregory J. and Fletcher, Linda M. (2011). Altered Lipid Metabolism in Hfe-Knockout Mice Promotes Severe NAFLD and Early Fibrosis. American Journal of Physiology: Gastrointestinal and Liver Physiology, 301 (5), 1-39. doi: 10.1152/ajpgi.00150.2011

Effect of adjuvant-induced systemic inflammation in rats on hepatic disposition kinetics of taurocholate

Roberts, Michael S., Liu, Xin, Zou, Yuhong, Siebert, Gerhard A., Chang, Ping, Whitehouse, Michael W., Fletcher, Linda and Crawford, Darrell H. G. (2011). Effect of adjuvant-induced systemic inflammation in rats on hepatic disposition kinetics of taurocholate. American Journal of Physiology-gastrointestinal And Liver Physiology, 300 (1), G130-G136. doi: 10.1152/ajpgi.00162.2010

Effect of low-level HCV viraemia at week 24 on HCV treatment response in genotype 1 patients

Baleriola, Cristina, Rawlinson, William D., Dore, Gregory J., Chaverot, Sandra, Stelzer-Braid, Sacha, Yoshihara, Motoko, Crawford, Darrell, Sievert, William, McCaughan, Geoffrey, Weltman, Martin, Cheng, Wendy, Rizkalla, Bishoy, Dubois, Dwight, Thommes, James and Roberts, Stuart (2011). Effect of low-level HCV viraemia at week 24 on HCV treatment response in genotype 1 patients. Antiviral Therapy, 16 (2), 173-180. doi: 10.3851/IMP1731

Low virological response and high relapse rates in hepatitis C genotype 1 patients with advanced fibrosis despite adequate therapeutic dosing

Cheng, Wendy S. C., Roberts, Stuart K., McCaughan, Geoffrey, Sievert, William, Weltman, Martin, Crawford, Darrell, Rawlinson, William, Marks, Philippa S., Thommes, James, Rizkalla, Bishoy, Yoshihara, Motoko, Dore, Gregory J. and CHARIOT Study Group (2010). Low virological response and high relapse rates in hepatitis C genotype 1 patients with advanced fibrosis despite adequate therapeutic dosing. Journal of Hepatology, 53 (4), 616-623. doi: 10.1016/j.jhep.2010.04.024

Ferritin and liver allocation? Impact on mortality not only on the waiting list but also after orthotopic liver transplantation should be considered: Reply

Crawford, Darrell H. G., Fletcher, Linda M. and Stuart, Katherine A. (2010). Ferritin and liver allocation? Impact on mortality not only on the waiting list but also after orthotopic liver transplantation should be considered: Reply. Hepatology, 52 (1), 393-393. doi: 10.1002/hep.23732

Serum ferritin concentration predicts mortality in patients awaiting liver transplantation

Walker, Nicole M., Stuart, Katherine A., Ryan, Rebecca J., Desai, Shireena, Saab, Sammy, Nicol, Jennifer A., Fletcher, Linda M. and Crawford, Darrell H. G. (2010). Serum ferritin concentration predicts mortality in patients awaiting liver transplantation. Hepatology, 51 (5), 1683-1691. doi: 10.1002/hep.23537

Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model

Zou, Yu-Hong, Liu, Xin, Khlentzos, Alexander M., Asadian, Peyman, Li, Peng, Thorling, Camilla A., Robertson, Thomas A., Fletcher, Linda M., Crawford, Darrell H. G. and Roberts, Michael S. (2010). Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model. Drug Metabolism and Pharmacokinetics, 25 (5), 442-449. doi: 10.2133/dmpk.DMPK-10-RG-031

Adding serum sodium to model for end-stage liver disease: Identifying those most at risk

Crawford, Darrell H. G. and Stuart, Katherine (2009). Adding serum sodium to model for end-stage liver disease: Identifying those most at risk. Journal of Gastroenterology and Hepatology, 24 (12), 1804-1806. doi: 10.1111/j.1440-1746.2009.06028.x

Altered clot kinetics in patients with non-alcoholic fatty liver disease

Hickman, I. J., Sullivan, C. M., Flight, S., Campbell, C., Crawford, D. H., Masci, P. P., O'Moore-Sullivan, T. M., Prins, J. B. and Macdonald, G. A. (2009). Altered clot kinetics in patients with non-alcoholic fatty liver disease. Annals of Hepatology, 8 (4), 331-338. doi: 10.1016/s1665-2681(19)31746-6

Fifty years of Australian gastroenterology and hepatology: A golden era of contributions to the region

Farrell, Geoffrey C., Yeomans, Neville D. and Crawford, Darrell (2009). Fifty years of Australian gastroenterology and hepatology: A golden era of contributions to the region. Journal of Gastroenterology and Hepatology, 24 (10), 1579-1586. doi: 10.1111/%28ISSN%291440-1746

Impact of high-dose peginterferon alfa-2a on virological response rates in patients with hepatitis C genotype 1: A randomized controlled trial

Roberts, Stuart K., Weltman, Martin D., Crawford, Darrell H. G., McCaughan, Geoffrey W., Sievert, William, Cheng, Wendy S., Rawlinson, William, Desmond, Paul V., Marks, Phillipa S., Yoshihara, Mokoto, Rizkalla, Bishoy, DePamphilis, Jean K., Dore, Gregory J. and for the Chariot Study Group (2009). Impact of high-dose peginterferon alfa-2a on virological response rates in patients with hepatitis C genotype 1: A randomized controlled trial. Hepatology, 50 (4), 1045-1055. doi: 10.1002/hep.23130

Rapamycin Inhibits Hepatic Fibrosis in Rats by Attenuating Multiple Profibrogenic Pathways

Bridle, K.R, Popa, C, Morgan, ML, Sobbe, AL, Clouston, AD, Fletcher, LM and Crawford, DHG (2009). Rapamycin Inhibits Hepatic Fibrosis in Rats by Attenuating Multiple Profibrogenic Pathways. Liver Transplantation, 15 (10), 1315-1324. doi: 10.1002/lt.21804

Reply: Utility of platelets and aspartate aminotransferase vs serum ferritin and serum hyaluronic acid as markers of cirrhosis in hemochromatosis

Crawford, Darrell H. G. and Ramm, Grant A. (2009). Reply: Utility of platelets and aspartate aminotransferase vs serum ferritin and serum hyaluronic acid as markers of cirrhosis in hemochromatosis. Hepatology, 49 (5), 1781-1782. doi: 10.1002/hep.22948

GESA: 50 years of progress

Crawford, Darrell (2009). GESA: 50 years of progress. Journal of Gastroenterology and Hepatology, 24 (Suppl. 3), S1-S1. doi: 10.1111/j.1440-1746.2009.06063.x

Hepcidin regulation in wild-type and Hfe knockout mice in response to alcohol consumption: Evidence for an alcohol-induced hypoxic response

Heritage, Mandy L., Murphy, Therese L., Bridle, Kim R., Anderson, Gregory J., Crawford, Darrell H. G. and Fletcher, Linda M. (2009). Hepcidin regulation in wild-type and Hfe knockout mice in response to alcohol consumption: Evidence for an alcohol-induced hypoxic response. Alcoholism, Clinical and Experimental Research, 33 (8), 1391-1400. doi: 10.1111/j.1530-0277.2009.00969.x

Serum hyaluronic acid with serum ferritin accurately predicts cirrhosis and reduces the need for liver biopsy in C282Y hemochromatosis

Crawford, D. H. G., Murphy, T. L., Ramm, L. E., Fletcher, L. M., Clouston, AD, Anderson, G. J., Subramaniam, V. N., Powell, L. W. and Ramm, G. A. (2009). Serum hyaluronic acid with serum ferritin accurately predicts cirrhosis and reduces the need for liver biopsy in C282Y hemochromatosis. Hepatology, 49 (2), 418-425. doi: 10.1002/hep.22650

Juvenile iron overload: Advances, but no answers

Walker, Nicole A., Crawford, Darrell H.G., Subramaniam, V. Nathan and Wallace, Daniel F. (2008). Juvenile iron overload: Advances, but no answers. Journal of Pediatrics, 153 (4), 588-588. doi: 10.1016/j.jpeds.2008.06.005

Cell-specific location of Hfe: It is the 'cyte that matters'

Crawford, Darrell H. G., Fletcher, Linda M. and Anderson, Gregory J. (2008). Cell-specific location of Hfe: It is the 'cyte that matters'. Hepatology, 48 (1), 336-338. doi: 10.1002/hep.22427

Patient-focused outcomes following detection in a hospital-based screening programme for C282Y haemochromatosis

McCullen, M. A., Fletcher, L. M., Dimeski, G., Pink, A., Powell, L. W., Crawford, D.H. and Hickman, P. E. (2008). Patient-focused outcomes following detection in a hospital-based screening programme for C282Y haemochromatosis. Internal Medicine Journal, 38 (8), 651-656. doi: 10.1111/j.1445-5994.2007.01578.x

Resolution of protein-losing enteropathy after successful heart transplantation in an adult patient with arrhythmogenic right ventricular cardiomyopathy (ARVC)

Korczyk, Darius, Clark, Paul, Crawford, Darrell, Maddicks-Law, Jo, Javorsky, George and Meyers, Deborah (2007). Resolution of protein-losing enteropathy after successful heart transplantation in an adult patient with arrhythmogenic right ventricular cardiomyopathy (ARVC). Journal of Heart and Lung Transplantation, 26 (9), 963-964. doi: 10.1016/j.healun.2007.07.003

Undetected hepatocellular carcinoma in patients undergoing liver transplantation: is associated with favorable outcome

Urahashi, T., Lynch, S. V., Kim, Y. H., Balderson, G. A., Fawcett, J. W., Crawford, D. H. and Strong, R. W. (2007). Undetected hepatocellular carcinoma in patients undergoing liver transplantation: is associated with favorable outcome. Hepatogastroenterology, 54 (76), 1192-1195.

Erratum: Somatostatin receptor expression, tumour response and quality of life in patients with advanced hepatocellular carcinoma treated with long-acting octreotide (British Journal of Cancer (2006) 95, (853-861) DOI: 10.1038/6603325)

Cebon, J., Findlay, M., Hargreaves, C., Stockler, M., Thompson, P., Boyer, M., Roberts, S., Poon, A., Scott, A. M., Kalff, V., Garas, G., Dowling, A., Crawford, D., Ring, J., Basser, R., Strickland, A., MacDonald, G., Green, M., Nowak, A., Dickman, B., Dhillon, H. and Gebski, V. (2007). Erratum: Somatostatin receptor expression, tumour response and quality of life in patients with advanced hepatocellular carcinoma treated with long-acting octreotide (British Journal of Cancer (2006) 95, (853-861) DOI: 10.1038/6603325). British Journal of Cancer, 96 (7), 1154-1154. doi: 10.1038/sj.bjc.6603674

Hepcidin gene expression is further suppressed in HFE-/-mice following chronic ethanol consumption

Fletcher, LM, Heritage, ML, Bridle, KR, Murphy, TL, Anderson, GJ and Crawford, DH (2007). Hepcidin gene expression is further suppressed in HFE-/-mice following chronic ethanol consumption. American Journal of Hematology, 82 (6), 528-529.

Lamivudine plus low-dose hepatitis B immunoglobulin to prevent recurrent hepatitis B following liver transplant

Gane, E. J., Angus, P. W., Strasser, S., Crawford, D. H. G., Ring, J., Jeffrey, G. P. and McCaughan, G. W. (2007). Lamivudine plus low-dose hepatitis B immunoglobulin to prevent recurrent hepatitis B following liver transplant. Gastroenterology, 132 (3), 931-937. doi: 10.1053/jgastro.2007.01.005

Somatostatin receptor expression, tumour response, and quality of life in patients with advanced hepatocellular carcinoma treated with long-acting octreotide

Cebon, J., Australasian Gastro-Intestinal Trials Group (AGITG) AG0001H Investigators, Findlay, M., Hargreaves, C., Stockler, M., Thompson, P., Boyer, M., Roberts, S., Poon, A., Scott, A. M., Kalff, V., Garas, G., Dowling, A., Crawford, D., Ring, J., Basser, R., Strickland, A., Macdonald, G., Green, M., Nowak, A., Dickman, B., Dhillon, H. and Gebski, V. (2006). Somatostatin receptor expression, tumour response, and quality of life in patients with advanced hepatocellular carcinoma treated with long-acting octreotide. British Journal of Cancer, 95 (7), 853-861. doi: 10.1038/sj.bjc.6603325

Hepatic pharmacokinetics of propranolol in rats with adjuvant-induced systemic inflammation

Hung, Daniel Y., Siebert, Gerhard A., Chang, Ping, Whitehouse, Michael W., Fletcher, Linda, Crawford, Darrell H. G. and Roberts, Michael S. (2006). Hepatic pharmacokinetics of propranolol in rats with adjuvant-induced systemic inflammation. American Journal of Physiology-gastrointestinal And Liver Physiology, 290 (2), G343-G351. doi: 10.1152/ajpgi.00155.2005

Hepcidin is down-regulated in alcoholic liver injury: Implications for the pathogenesis of alcoholic liver disease

Bridle, Kim R., Cheung, Ting-Kin, Murphy, Therese L., Walters, Margaret M., Anderson, Gregory J., Crawford, Darrell H. G. and Fletcher, Linda M. (2006). Hepcidin is down-regulated in alcoholic liver injury: Implications for the pathogenesis of alcoholic liver disease. Alcoholism-clinical And Experimental Research, 30 (1), 106-112. doi: 10.1111/j.1530-0277.2006.00002.x

Screening for hemochromatosis in asymptomatic subjects with or without a family history

Powell, Lawrie W., Dixon, Jeannette L., Ramm, Grant A., Purdie, David M., Lincoln, Douglas J., Anderson, Gregory J., Subramaniam, V. Nathan, Hewett, David G., Searle, Jeffrey W., Fletcher, Linda M., Crawford, Darrell H., Rodgers, Helen, Allen, Katrina J., Cavanaugh, Juleen A. and Bassett, Mark L. (2006). Screening for hemochromatosis in asymptomatic subjects with or without a family history. Archives of Internal Medicine, 166 (3), 294-301. doi: 10.1001/archinte.166.3.294

Ferroportin disease due to the A77D mutation in Australia

Subramaniam, V. N., Wallace, D. F., Dixon, J. L., Fletcher, L. M. and Crawford, D. H. (2005). Ferroportin disease due to the A77D mutation in Australia. Gut, 54 (7), 1048-1049. doi: 10.1136/gut.2005.069021

No hepatic iron overload 12 years after liver transplantation for hereditary hemochromatosis - reply

Crawford, Darrell and Fletcher, Linda (2004). No hepatic iron overload 12 years after liver transplantation for hereditary hemochromatosis - reply. Hepatology, 40 (3), 762-762. doi: 10.1002/hep.20417

No hepatic iron overload 12 years after liver transplantation for hereditary hemochromatosis [3] (multiple letters)

Bralet, Marie-Pierre, Duclos-Vallee, Jean-Charles, Castaing, Denis, Samuel, Didier, Guettier, Catherine, Crawford, Darrell and Fletcher, Linda (2004). No hepatic iron overload 12 years after liver transplantation for hereditary hemochromatosis [3] (multiple letters). Hepatology, 40 (3), 762-762. doi: 10.1002/hep.20398

Reply

Anderson, Gregory J., Frazer, David M., Bridle, Kim R., Crawford, Darell H. G., Subramaniam, V. Nathan, Powell, Lawrie W. and Ramm, Grant A. (2004). Reply. Gastroenterology, 126 (2), 616-616. doi: 10.1053/j.gastro.2003.12.054

Increased duodenal expression of divalent metal transporter 1 and iron-regulated gene 1 in cirrhosis

Stuart, KA, Anderson, GJ, Frazer, DM, Murphy, TL, Powell, LW, Fletcher, LM and Crawford, DH (2004). Increased duodenal expression of divalent metal transporter 1 and iron-regulated gene 1 in cirrhosis. Hepatology, 39 (2), 492-499. doi: 10.1002/hep.20038

Patient and graft survival after liver transplantation for hereditary hemochromatosis: Implications for pathogenesis

Crawford, DHG, Fletcher, LM, Hubscher, SG, Stuart, KA, Gane, E, Angus, PW, Jeffrey, GP, McCaughan, GW, Kerlin, P, Powell, LW and Elias, EE (2004). Patient and graft survival after liver transplantation for hereditary hemochromatosis: Implications for pathogenesis. Hepatology, 39 (6), 1655-1662. doi: 10.1002/hep.20242

Tumor progression in hepatocellular carcinoma: Relationship with tumor stroma and parenchymal disease

Lockwood, D. S. R, Yeadon, T. M., Clouston, A. D., Crawford, D. G., Fawcett, J., Callaghan, S. A. and Gotley, D. C. (2003). Tumor progression in hepatocellular carcinoma: Relationship with tumor stroma and parenchymal disease. Journal of Gastroenterology And Hepatology, 18 (6), 666-672. doi: 10.1046/j.1440-1746.2003.03018.x

Identification and characterization of the hepatic stellate cell transferrin receptor

Bridle, Kim R., Crawford, Darrell H. G. and Ramm, Grant A. (2003). Identification and characterization of the hepatic stellate cell transferrin receptor. American Journal of Pathology, 162 (5), 1661-1667. doi: 10.1016/S0002-9440(10)64300-3

Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis

Bridle, K. R., Frazer, D. M., Wilkins, S. J., Dixon, J. L., Purdie, D. M., Crawford, D. H. G., Subramaniam, V. N, Powell, L. W., Anderson, G. J. and Ramm, G. A. (2003). Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet, 361 (9358), 669-673. doi: 10.1016/S0140-6736(03)12602-5

Duodenal expression of iron transport molecules in untreated haemochromatosis subjects

Stuart, KA, Anderson, GJ, Frazer, DM, Powell, LW, McCullen, M, Fletcher, LM and Crawford, DHG (2003). Duodenal expression of iron transport molecules in untreated haemochromatosis subjects. Gut, 52 (7), 953-959. doi: 10.1136/gut.52.7.953

Effect of alcohol on iron storage diseases of the liver

Fletcher, LM, Bridle, KR and Crawford, DHG (2003). Effect of alcohol on iron storage diseases of the liver. Best Practice & Research In Clinical Gastroenterology, 17 (4), 663-677. doi: 10.1053/ybega.2003.378

Evidence for a sub-morphological inflammatory process in the liver in haemochromatosis

Bridle, K. R., Crawford, D. H. G., Fletcher, L. M., Smith, J. L., Powell, L. W. and Ramm, G. A. (2003). Evidence for a sub-morphological inflammatory process in the liver in haemochromatosis. Journal of Hepatology, 38 (4), 426-433. doi: 10.1016/S0168-8278(02)00444-0

Liver transplantation for HCV-associated liver cirrhosis: Predictors of outcomes in a population with significant genotype 3 and 4 distribution

Zekry, A, Whiting, P, Crawford, DH, Angus, PW, Jeffrey, GP, Padbury, RT, Gane, EJ and McCaughan, GW (2003). Liver transplantation for HCV-associated liver cirrhosis: Predictors of outcomes in a population with significant genotype 3 and 4 distribution. Liver Transplantation, 9 (4), 339-347. doi: 10.1053/jlts.2003.50063

The influence of viral genotypes and rejection episodes on the recurrence of hepatitis C after liver transplantation

Sugo, H, Balderson, GA, Crawford, DHG, Fawcett, J, Lynch, SV, Strong, RW and Futagawa, S (2003). The influence of viral genotypes and rejection episodes on the recurrence of hepatitis C after liver transplantation. Surgery Today, 33 (6), 421-425. doi: 10.1007/s10595-002-2537-5

Concordance of iron indices in homozygote and heterozygote sibling pairs in hemochromatosis families: implications for family screening

Whiting, PW, Fletcher, LM, Dixon, JK, Gochee, P, Powell, LW and Crawford, DHG (2002). Concordance of iron indices in homozygote and heterozygote sibling pairs in hemochromatosis families: implications for family screening. Journal of Hepatology, 37 (3), 309-314. doi: 10.1016/S0168-8278(02)00216-7

Excess alcohol greatly increases the prevalence of cirrhosis in hereditary hemochromatosis

Fletcher, Linda M., Dixon, Jeanette L., Purdie, David M., Powell, Lawrie W. and Crawford, Darrel H.G. (2002). Excess alcohol greatly increases the prevalence of cirrhosis in hereditary hemochromatosis. Gastroenterology, 122 (2), 281-289. doi: 10.1053/gast.2002.30992

GH treatment in adults with chronic liver disease: A randomized, double-blind, placebo-controlled, cross-over study

Wallace, J. D., Abbott-Johnson, W. J., Crawford, D. H. G., Barnard, R., Potter, J. M. and Cuneo, R. C. (2002). GH treatment in adults with chronic liver disease: A randomized, double-blind, placebo-controlled, cross-over study. Journal of Clinical Endocrinology And Metabolism, 87 (6), 2751-2759. doi: 10.1210/jc.87.6.2751

Overseas liver transplantation for hepatitis C in Japanese patients: A comparison with patients from Australia/New Zealand

Sugo, H, Balderson, GA, Crawford, DHG, Fawcett, J, Lynch, SV, Strong, RW and Futagawa, S (2002). Overseas liver transplantation for hepatitis C in Japanese patients: A comparison with patients from Australia/New Zealand. Transplantation Proceedings, 34 (8), 3323-3324. doi: 10.1016/S0041-1345(02)03599-6

Screening for hemochromatosis

McCullen, MA, Crawford, DHG and Hickman, PE (2002). Screening for hemochromatosis. Clinica Chimica Acta, 315 (1-2), 169-186. doi: 10.1016/S0009-8981(01)00711-2

Alcohol and the pancreas

Haber, Paul, Nakamura, Masahiko, Tsuchimoto, Kanji, Ishii, Hiromasa, Keogh, Gregory W., Apte, Minoti V., Moran, Corey S., Stewart, Nancy L., Crawford, Darrell H. G., Pirola, Romano C., McCaughan, Geoffrey W., Ramm, Grant A., Wilson, Jeremy S., Nishino, H., Kohno, M., Aizawa, R., Tajima, N., Maruyama, K., Takahashi, H., Matsushita, S., Okuyama, K., Yokoyama, A., Nakamura, Y., Shirakura, K., Conigrave, Katherine M., Hu, B. Frank, Camargo Jr, Carlos A., Stampfer, Meir J., Willett, Walter C. and Rimm, Eric B. (2001). Alcohol and the pancreas. Alcoholism: Clinical and Experimental Research, 25 (s1), 244S-250S. doi: 10.1111/j.1530-0277.2001.tb02403.x

Role of myofibroblasts in tumour encapsulation of hepatocellular carcinoma in haemochromatosis

Bridle, Kim R., Crawford, Darrell H. G., Powell, Lawrie W. and Ramm, Grant A. (2001). Role of myofibroblasts in tumour encapsulation of hepatocellular carcinoma in haemochromatosis. Liver, 21 (2), 96-104. doi: 10.1034/j.1600-0676.2001.021002096.x

Vitamin B12 and hepatitis C: Molecular biology and human pathology

Lott, William B., Takyar, Seyedtaghi S., Tuppen, Joseph, Crawford, Darrell H. G., Harrison, Michael, Sloots, Theo P. and Gowans, Eric J. (2001). Vitamin B12 and hepatitis C: Molecular biology and human pathology. Proceedings of the National Academy of Sciences, 98 (9), 4916-4921. doi: 10.1073/pnas.081072798

Estimation of body water compartments in cirrhosis by multiple-frequency bioelectrical-impedance analysis

Lehnert, ME, Clarke, DD, Gibbons, JG, Ward, LC, Golding, SM, Shepherd, RW, Cornish, BH and Crawford, DHG (2001). Estimation of body water compartments in cirrhosis by multiple-frequency bioelectrical-impedance analysis. Nutrition, 17 (1), 31-34. doi: 10.1016/S0899-9007(00)00473-1

Lipid peroxidation in hepatic steatosis in humans is associated with hepatic fibrosis and occurs predominately in acinar zone 3

Macdonald, G., Bridle, K. R., Ward, P. J., Walker, N. I., Houglum, K., George, D. K., Smith, J. L., Powell, L. W., Crawford, D. and Ramm, G. A. (2001). Lipid peroxidation in hepatic steatosis in humans is associated with hepatic fibrosis and occurs predominately in acinar zone 3. Journal of Gastroenterology and Hepatology, 16 (6), 599-606. doi: 10.1046/j.1440-1746.2001.02445.x

Role of cytokine gene polymorphisms in acute rejection and renal impairment after liver transplantation

Jonsson, Julie R., Hong, Cui, Purdie, David M., Hawley, Carmel, Isbel, Nicky, Butler, Maree, Balderson, Glenda A., Clouston, Andrew D., Pandeya, Nirmala, Stuart, Katherine, Edwards-Smith, Catherine, Crawford, Darrel H., Fawcett, Jonathon and Powell, Elizabeth E. (2001). Role of cytokine gene polymorphisms in acute rejection and renal impairment after liver transplantation. Liver Transplantation, 7 (3), 255-263. doi: 10.1053/jlts.2001.22450

Increased hepatic iron and cirrhosis: no evidence for an adverse effect on patient outcome following liver transplantation

Stuart, Katherine A., Fletcher, Linda M., Clouston, Andrew D., Lynch, Steve V., Purdie, David M., Kerlin, Paul and Crawford, Darrell H. G. (2000). Increased hepatic iron and cirrhosis: no evidence for an adverse effect on patient outcome following liver transplantation. Hepatology, 32 (6), 1200-1207. doi: 10.1053/jhep.2000.20348

Why there is discordance in reported decision thresholds for transferrin saturation when screening for hereditary hemochromatosis

McCullen, M.A., Crawford, D.H.G., Dimeski, G., Tate, J. and Hickman, P.E. (2000). Why there is discordance in reported decision thresholds for transferrin saturation when screening for hereditary hemochromatosis. Hepatology, 32 (6), 1410-1411.

Hepatocellular carcinoma in Australia: largely preventable

Crawford, Darrell H. G. and Fawcett, Jonathon (2000). Hepatocellular carcinoma in Australia: largely preventable. Medical Journal of Australia, 173 (8), 396-397. doi: 10.5694/j.1326-5377.2000.tb139263.x

Morphology of liver repair following cholestatic liver injury: Resolution of ductal hyperplasia, matrix deposition and regression of myofibroblasts

Ramm, G. A., Carr, S. C., Bridle, K. R., Li, L., Britton, R. S., Crawford, D. H. G., Vogler, C. A., Bacon, B. R. and Tracy, T. F. (2000). Morphology of liver repair following cholestatic liver injury: Resolution of ductal hyperplasia, matrix deposition and regression of myofibroblasts. Liver, 20 (5), 387-396. doi: 10.1034/j.1600-0676.2000.020005387.x

Combination low-dose hepatitis B immune globulin and lamivudine therapy provides effective prophylaxis against posttransplantation hepatitis B

Angus, P. W., McCaughan, G. W., Gane, E. J., Crawford, D. H. G. and Harley, H. (2000). Combination low-dose hepatitis B immune globulin and lamivudine therapy provides effective prophylaxis against posttransplantation hepatitis B. Liver Transplantation, 6 (4), 429-433. doi: 10.1053/jlts.2000.8310

Screening for hemochromatosis

Crawford, D. H. G. and Hickman, P. (2000). Screening for hemochromatosis. Hepatology, 31 (5), 1192-1193. doi: 10.1053/he.2000.7354

Confirmation of the Role of the Mayo Risk Score as a Predictor of Resource Utilization After Orthotopic Liver Transplantation for Primary Biliary Cirrhosis

GilroyRichardK, LynchStephenV, StrongRussellW, KerlinPaul, BaldersonGlendaA, StuartKatherineA and Crawford, Darrell H. G. (2000). Confirmation of the Role of the Mayo Risk Score as a Predictor of Resource Utilization After Orthotopic Liver Transplantation for Primary Biliary Cirrhosis. Liver Transplantation, 6 (6), 749-752. doi: 10.1053/jlts.2000.9746

Detection of male DNA in the liver of female patients with primary biliary cirrhosis

Fanning, Peter A., Jonsson, Julie R., Clouston, Andrew D., Edwards-Smith, Cathy, Balderson, Glenda A., Macdonald, Graeme A., Crawford, Darrell H. G., Kerlin, Paul, Powell, Lawrie W. and Powell, Elizabeth E. (2000). Detection of male DNA in the liver of female patients with primary biliary cirrhosis. Journal of Hepatology, 33 (5), 690-695. doi: 10.1016/S0168-8278(00)80297-4

Host genetic factors influence disease progression in chronic hepatitis C

Powell, E. E., Edwards-Smith, C. J., Hay, J. L., Clouston, A. D., Crawford, D. H., Shorthouse, C., Purdie, D. M. and Jonsson, J. R. (2000). Host genetic factors influence disease progression in chronic hepatitis C. Hepatology, 31 (4), 828-833. doi: 10.1053/he.2000.6253

Activation of pancreatic stellate cells in human and experimental pancreatic fibrosis

Haber, P. S., Keogh, G. W., Apte, M. V., Moran, C. S., Stewart, N. L., Crawford, D. H. G., Pirola, R. C., McCaughan, G. W., Ramm, G. A. and Wilson, J. S. (1999). Activation of pancreatic stellate cells in human and experimental pancreatic fibrosis. American Journal of Pathology, 155 (4), 1087-1095. doi: 10.1016/S0002-9440(10)65211-X

Case report: Lamivudine therapy for submassive hepatic necrosis due to reactivation of Hepatitis B following chemotherapy

Maguire, C. M., Crawford, D. H. G., Hourigan, L. F., Clouston, A. D., Walpole, E. T. and Powell, E. E. (1999). Case report: Lamivudine therapy for submassive hepatic necrosis due to reactivation of Hepatitis B following chemotherapy. Journal of Gastroenterology and Hepatalogy, 14 (8), 801-803. doi: 10.1046/j.1440-1746.1999.01961.x

Elevated serum type IV collagen: a sensitive indicator of the presence of cirrhosis in haemochromatosis

George, D. Keith, Ramm, Grant A., Walker, Neal I., Powell, Lawrie W. and Crawford, Darrell H. G. (1999). Elevated serum type IV collagen: a sensitive indicator of the presence of cirrhosis in haemochromatosis. Journal of Hepatology, 31 (1), 47-52. doi: 10.1016/S0168-8278(99)80162-7

Linkage disequilibrium analysis in Australian haemochromatosis patients indicates bipartite association with clinical expression

Pratiwi, Rarastoeti, Fletcher, Linda M., Pyper, Wendy R., Do, Kim-Anh, Crawford, Darrell H. G., Powell, Lawrie W. and Jazwinska, Elizabeth C. (1999). Linkage disequilibrium analysis in Australian haemochromatosis patients indicates bipartite association with clinical expression. Journal of Hepatology, 31 (1), 39-46. doi: 10.1016/S0168-8278(99)80161-5

Utility of genotyping in diagnosis of genetic haemochromatosis

Crawford, D. H. G. and Fletcher, L. M. (1999). Utility of genotyping in diagnosis of genetic haemochromatosis. Journal of Gastroenterology and Hepatology, 14 (5), 401-402. doi: 10.1046/j.1440-1746.1999.01887.x

Haemochromatosis

Crawford, D. H. G. and RammGA (1999). Haemochromatosis. Trends in Endocrinology and Metabolism, 10 (1), 14-17. doi: 10.1016/S1043-2760(98)00103-9

The DRD2 A1 allele: a behavioural genetic risk factor in hepatitis C infection of persistent drug abusers

Lawford, B., Young, R. M., Noble, E. P., Crawford, D., Rowell, J., Shadforth, S., Ritchie, T., Zhang, X. and Cooksley, G. E. (1999). The DRD2 A1 allele: a behavioural genetic risk factor in hepatitis C infection of persistent drug abusers. Addiction Biology, 4 (1), 61-66. doi: 10.1080/13556219971858

Contribution of hepatic parenchymal and nonparenchymal cells to hepatic fibrogenesis in biliary atresia

Ramm, G. A., Nair, V. G., Bridle, K. R., Shepherd, R. W. and Crawford, D. H. G. (1998). Contribution of hepatic parenchymal and nonparenchymal cells to hepatic fibrogenesis in biliary atresia. American Journal of Pathology, 153 (2), 527-535. doi: 10.1016/S0002-9440(10)65595-2

Haemochromatosis

Crawford, D. H. G., Leggett, B. A. and Powell, L. W. (1998). Haemochromatosis. Bailliere's Clinical Gastroenterology, 12 (2), 209-225. doi: 10.1016/S0950-3528(98)90131-2

Evidence for altered hepatic matrix degradation in genetic haemochromatosis

George, D.K., Ramm, G.A., Powell, L.W., Fletcher, L.M., Walker, N.I., Cowley, L.L. and Crawford, D.H.G. (1998). Evidence for altered hepatic matrix degradation in genetic haemochromatosis. Gut, 42 (5), 715-720. doi: 10.1136/gut.42.5.715

Expression of HLA-linked hemochromatosis in subjects homozygous or heterozygous for the C282Y mutation

Crawford, D. H. G., Jazwinska, E. C., Cullen, L. M. and Powell, L. W. (1998). Expression of HLA-linked hemochromatosis in subjects homozygous or heterozygous for the C282Y mutation. Gastroenterology, 114 (5), 1003-1008. doi: 10.1016/S0016-5085(98)70320-8

The C282Y mutation in the haemochromatosis gene (HFE) and hepatitis C virus infection are independent cofactors for porphyria cutanea tarda in Australian patients

Stuart, K. A., Busfield, F., Jazwinska, E. C., Gibson, P., Butterworth, L. A., Cooksley, W. G., Powell, L. W. and Crawford, D. H. G. (1998). The C282Y mutation in the haemochromatosis gene (HFE) and hepatitis C virus infection are independent cofactors for porphyria cutanea tarda in Australian patients. Journal of Hepatology, 28 (3), 404-409. doi: 10.1016/S0168-8278(98)80313-9

Distribution of transferrin saturation in an Australian population: Relevance to the early diagnosis of hemochromatosis

McLarenCE, McLachlanGJ, HallidayJW, WebbSI, LeggettBA, JazwinskaEC, Crawford, DHG, GordeukVR, McLarenGD and PowellLW (1998). Distribution of transferrin saturation in an Australian population: Relevance to the early diagnosis of hemochromatosis. Gastroenterology, 114 (3), 543-549. doi: 10.1016/S0016-5085(98)70538-4

Hepatic iron stores and steatosis are associated with lipid peroxidation and fibrosis

Macdonald, GA, Bridle, KR, Ward, PJ, Walker, NI, Houglum, K, Powell, LW, Crawford, DHG and Ramm, GA (1998). Hepatic iron stores and steatosis are associated with lipid peroxidation and fibrosis. Hepatology, 28 (4, Part 2 Suppl.), 639A-639A.

The haemochromatosis gene

Crawford, D. H. G. (1997). The haemochromatosis gene. Australian and New Zealand Journal of Medicine, 27 (6), 639-641. doi: 10.1111/j.1445-5994.1997.tb00989.x

Neonatal screening for the hemochromatosis defect

Cullen, L. M., Summerville, L., Glassick, T. V., Crawford, D. H. G., Powell, L. W. and Jazwinska, E. C. (1997). Neonatal screening for the hemochromatosis defect. Blood, 90 (10), 4236-4237.

Excess iron induces hepatic oxidative stress and transforming growth factor beta 1 in genetic hemochromatosis

Houglum, K., Ramm, G. A., Crawford, D. H. G., Witztum, J. L., Powell, L. W. and Chojkier, M. (1997). Excess iron induces hepatic oxidative stress and transforming growth factor beta 1 in genetic hemochromatosis. Hepatology, 26 (3), 605-610. doi: 10.1002/hep.510260311

A techniques for the culture of Barrett's oesophageal cells

Khan, S. M., Pillay, S. P., Papadimos, D., Yong, J. W. K., Roberts, H. J. V. and Crawford, D. H. (1997). A techniques for the culture of Barrett's oesophageal cells. Journal of Gastroenterology and Hepatology, 12 (8), 606-611. doi: 10.1111/j.1440-1746.1997.tb00493.x

Evidence that 'myofibroblast-like' cells are the cellular source of capsular collagen in hepatocellular carcinoma

Ooi, L. P. J., Crawford, D. H. G., Gotley, D. C., Clouston, A. D., Strong, R. W., Gobe, G. C., Halliday, J. W., Bridle, K. R. and Ramm, G. A. (1997). Evidence that 'myofibroblast-like' cells are the cellular source of capsular collagen in hepatocellular carcinoma. Journal of Hepatology, 26 (4), 798-807. doi: 10.1016/S0168-8278(97)80245-0

Hepatic stellate cell activation in genetic haemochromatosis - Lobular distribution, effect of increasing hepatic iron and response to phlebotomy

Ramm, G. A., Crawford, D. H. G., Powell, L. W., Walker, N. I., Fletcher, L. M. and Halliday, J. W. (1997). Hepatic stellate cell activation in genetic haemochromatosis - Lobular distribution, effect of increasing hepatic iron and response to phlebotomy. Journal of Hepatology, 26 (3), 584-592. doi: 10.1016/S0168-8278(97)80424-2

Determinants of disease expression in Australian haemochromatosis patients

Crawford, D. H. G. (1996). Determinants of disease expression in Australian haemochromatosis patients. Journal of Gastroenterology and Hepatology, 11 (11), 1043-1045. doi: 10.1111/j.1440-1746.1996.tb00034.x

Antibacterial-induced hepatotoxicity - Incidence, prevention and management

George, D. K. and Crawford, D. H. G. (1996). Antibacterial-induced hepatotoxicity - Incidence, prevention and management. Drug Safety, 15 (1), 79-85. doi: 10.2165/00002018-199615010-00007

Factors influencing disease expression in hemochromatosis

Crawford, D. H. G., Powell, L. W., Halliday, J. W. and Leggett, B. A. (1996). Factors influencing disease expression in hemochromatosis. Annual Review of Nutrition, 16, 139-160. doi: 10.1146/annurev.nutr.16.1.139

Flucloxacillin associated cholestatic hepatitis. An Australian and Swedish epidemic?

Devereaux, B. M., Crawford, D. H. G., Purcell, P., Powell, L. W. and Roeser, H. P. (1995). Flucloxacillin associated cholestatic hepatitis. An Australian and Swedish epidemic?. European Journal of Clinical Pharmacology, 49 (1-2), 81-85. doi: 10.1007/BF00192363

Evidence that the ancestral haplotype in Australian hemochromatosis patients may be associated with a common mutation in the gene

Crawford, D. H. G., Powell, L. W., Leggett, B. A., Francis, J. S., Fletcher, L. M., Webb, S. I., Halliday, J. W. and Jazwinska, E. C. (1995). Evidence that the ancestral haplotype in Australian hemochromatosis patients may be associated with a common mutation in the gene. American Journal of Human Genetics, 57 (2), 362-367.

Renal glomerular lesions in unselected patients with cirrhosis undergoing orthotopic liver transplantation

Axelsen, R. A., Crawford, D. H. G., Endre, Z. H., Lynch, S. V., Balderson, G. A., Strong, R. W. and Fleming, S. J. (1995). Renal glomerular lesions in unselected patients with cirrhosis undergoing orthotopic liver transplantation. Pathology, 27 (3), 237-246. doi: 10.1080/00313029500169053

Trigeminal Sensory Neuropathy Induced by Interferon-Alpha Therapy

ReadSJ, Crawford, D. H. G., PenderMP and GrahamMacdonald (1995). Trigeminal Sensory Neuropathy Induced by Interferon-Alpha Therapy. Australian and New Zealand Journal of Medicine, 25 (1), 54-54. doi: 10.1111/j.1445-5994.1995.tb00580.x

Body composition in nonalcoholic cirrhosis: The effect of disease etiology and severity on nutritional compartments

Crawford, D. H. G., Shepherd, R. W., Halliday, J. W., Cooksley, G. W. G. E., Golding, S. D., Cheng, W. S. C. and Powell, L. W. (1994). Body composition in nonalcoholic cirrhosis: The effect of disease etiology and severity on nutritional compartments. Gastroenterology, 106 (6), 1611-1617. doi: 10.1016/0016-5085(94)90418-9

Clinical Applicability of Bioelectric Impedance to Measure Body-Composition in Health and Disease

Holt, TL, Cui, CT, Thomas, BJ, Ward, LC, Quirk, PC, Crawford, D and Shepherd, RW (1994). Clinical Applicability of Bioelectric Impedance to Measure Body-Composition in Health and Disease. Nutrition, 10 (3), 221-224.

Distribution of body water in patients with cirrhosis: The effect of liver transplantation

Crawford, D. H. G., Halliday, J. W., Cooksley, W. G. E., Murphy, T. L., Golding, S. D., Wallace, J. D., Cuneo, R. C., Lynch, S. V., Strong, R. J. and Powell, L. W. (1993). Distribution of body water in patients with cirrhosis: The effect of liver transplantation. Hepatology, 17 (6), 1016-1021. doi: 10.1016/0270-9139(93)90116-5

Concordance of iron storage in siblings with genetic hemochromatosis: Evidence for a predominantly genetic effect on iron storage

Crawford, Darrell H. G. , Halliday, June W. , Summers, Kim M. , Bourke, Michael J. and Powell, Lawrie W. (1993). Concordance of iron storage in siblings with genetic hemochromatosis: Evidence for a predominantly genetic effect on iron storage. Hepatology, 17 (5), 833-837. doi: 10.1002/hep.1840170514

Concordance of iron storage in siblings with genetic hemochromatosis: Evidence for a predominantly genetic effect on iron storage

Crawford, D. H. G., Halliday, J. W., Summers, K. M., Bourke, M. J. and Powell, L. W. (1993). Concordance of iron storage in siblings with genetic hemochromatosis: Evidence for a predominantly genetic effect on iron storage. Hepatology, 17 (5), 833-837. doi: 10.1016/0270-9139(93)90160-O

Pathogenesis and assessment of malnutrition in liver disease

Crawford, D. H. G., Cuneo, R. C. and Shepherd, R. W. (1993). Pathogenesis and assessment of malnutrition in liver disease. Journal of Gastroenterology and Hepatology, 8 (1), 89-94. doi: 10.1111/j.1440-1746.1993.tb01180.x

Glomerular abnormalities in children undergoing orthotopic liver transplantation

Chin, S. E., Axelsen, R. A., Crawford, D. H. G., Endre, Z. H., Lynch, S. V., Balderson, G. A., Strong, R. W., Shepherd, R. W., Burke, J. R. and Fleming, S. J. (1992). Glomerular abnormalities in children undergoing orthotopic liver transplantation. Pediatric Nephrology, 6 (5), 407-411. doi: 10.1007/BF00873994

Fulminant hepatic failure complicating the treatment of Mycobacterium xenopi - Reply

Powell, L. W. and Crawford, D. H. G. (1992). Fulminant hepatic failure complicating the treatment of Mycobacterium xenopi - Reply. Medical Journal of Australia, 156 (11), 812-812.

Universal occurrence of glomerular abnormalities in patients receiving liver transplants

Crawford, D. H. G., Endre, Z. H., Axelsen, R. A., Lynch, S. V., Balderson, G. A., Strong, R. W., Kerlin, P., Powell, L. W. and Fleming, S. J. (1992). Universal occurrence of glomerular abnormalities in patients receiving liver transplants. American Journal of Kidney Diseases, 19 (4), 339-344. doi: 10.1016/S0272-6386(12)80451-3

Persistent glomerular abnormalities following orthotopic liver transplantation

Fleming, S. J., Axelsen, R. A., Lynch, S. L., Endre, Z. H., Balderson, G. A. and Crawford, D. H. G. (1991). Persistent glomerular abnormalities following orthotopic liver transplantation. Nephron, 58 (4), 486-486. doi: 10.1159/000186487

Current concepts in rational therapy for haemochromatosis

Crawford, D. H. G. and Halliday, J. W. (1991). Current concepts in rational therapy for haemochromatosis. Drugs, 41 (6), 875-882. doi: 10.2165/00003495-199141060-00005

Wilson's disease in an Australian Aborigine

Crawford, D. H. G., Shepherd, R., Cooksley, W. G. E., Patrick, M. and Powell, L. W. (1990). Wilson's disease in an Australian Aborigine. Journal of Gastroenterology and Hepatology, 5 (6), 705-707. doi: 10.1111/j.1440-1746.1990.tb01130.x

Percutaneous endoscopic gastrostomy: a two-year experience

George, J., Crawford, D., Lewis, T., Shepherd, R. and Ward, M. (1990). Percutaneous endoscopic gastrostomy: a two-year experience. Medical Journal of Australia, 152 (1), 17-19. doi: 10.5694/j.1326-5377.1990.tb124421.x

Reactive oxygen species-mediated hepatic stellate cell activation via PI3K in liver cancer

Ruan, Qi, Cao, Lu, Yang, Haotian, Burke, Leslie, Bridle, Kim, Crawford, Darrell and Liang, Xiaowen (2023). Reactive oxygen species-mediated hepatic stellate cell activation via PI3K in liver cancer. EASL Congress 2023, Vienna, Austria, 21 - 24 June 2023. Amsterdam, Netherlands: Elsevier BV.

Attenuation of receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain like pseudokinase (MLKL) blocks the TRIF-RIPK3-MLKL-driven necroptotic cell death in steatotic hepatocytes undergoing ischemic injury

Baidya, R., Jaskowski, L., Gautheron, J., Jayachandran, A., Wang, H., Thevenot, P., Cohen, A., Crawford, D. and Bridle, K. (2019). Attenuation of receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain like pseudokinase (MLKL) blocks the TRIF-RIPK3-MLKL-driven necroptotic cell death in steatotic hepatocytes undergoing ischemic injury. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “The Universe Within”, Adelaide Convention Centre, 8-10 September 2019. Hoboken, NJ, United States: Wiley-Blackwell. doi: 10.1111/jgh.14798

Enrichment of multiple immune checkpoints in cholangiocarcinoma cancer stem cells

Cao, L., Shrestha, R., Bridle, K., Crawford, D. and Jayachandran, A. (2019). Enrichment of multiple immune checkpoints in cholangiocarcinoma cancer stem cells. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “The Universe Within”, Adelaide Convention Centre, 8-10 September 2019. Hoboken, NJ, United States: Wiley-Blackwell. doi: 10.1111/jgh.14797

Tumor necrosis factor-alpha promotes epithelial-to-mesenchymal transition and expression of immune checkpoint molecules in hepatocellular carcinoma

Shrestha, R., Bridle, K., Cao, L., Crawford, D. and Jayachandran, A. (2019). Tumor necrosis factor-alpha promotes epithelial-to-mesenchymal transition and expression of immune checkpoint molecules in hepatocellular carcinoma. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “The Universe Within”, Adelaide Convention Centre, 8-10 September 2019. Richmond, VIC, Australia: Wiley-Blackwell.

Comparable Levels of Inflammatory Mediators in Portal Venous Blood Collected from Organ Donors Donating after Circulatory Death and those Donating after Brain Death

Reiling, Janske, Hohenhaus, Daniel M., Sweet, Matt J., Raj, Ashok S., Campbell, Catherine M., Bridle, Kim R., Santrampurwala, Nishreen, Britton, Laurence J., Crawford, Darrell H. G., Dejong, Cornelis H. C. and Fawcett, Jonathan (2018). Comparable Levels of Inflammatory Mediators in Portal Venous Blood Collected from Organ Donors Donating after Circulatory Death and those Donating after Brain Death. 14th World Congress of the International-Pancreas-and-Islet-Transplant-Association (IPITA), Monterey Ca, 24-27 September 2013. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.tp.0000543959.06247.92

Inflammatory Pathways in Adipocytes Are Activated By Ferritin and Iron

Jaskowski, Lesley, Bridle, Kim, Britton, Laurence J., Jayachandran, Apama, Ramm, Grant A. and Crawford, Darrell H. G. (2018). Inflammatory Pathways in Adipocytes Are Activated By Ferritin and Iron. Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, San Francisco, CA, United States, 9-13 November 2018. Hoboken, NJ United States: Wiley.

Necroptosis Contributes to Cell Death of Steatotic Hepatocytes Following Ischaemic Injury

Baidya, Raji, Jaskowski, Lesley, Jayachandran, Aparna, Thevenot, Paul, Cohen, Ari J., Crawford, Darrell H.G. and Bridle, Kim (2018). Necroptosis Contributes to Cell Death of Steatotic Hepatocytes Following Ischaemic Injury. Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) / Liver Meeting, San Francisco, California, 9-13 November 2018 . Hoboken, NJ, United States: John Wiley & Sons.

Prognostic Impact of Immune Checkpoint Inhibitor Expression and Its Association with Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma

Shrestha, Ritu, Prithiviraj, Prashanth, Bridle, Kim, Anake, Matthew, Crawford, Darrell H. G. and Jayachandran, Aparna (2018). Prognostic Impact of Immune Checkpoint Inhibitor Expression and Its Association with Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma. Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) / Liver Meeting, San Francisco, CA United States, 9-13 November 2018. Hoboken, NJ United States: Wiley.

Do macrophages play a role in the development of endotoxin-induced biliary injury in rats?

Reiling, J., Bridle, K. B., Schaap, F. G., Jaskowski, L., Santrampurwala, N., Britton, L. J., Campbell, C. M., Damink, S. W. M. Olde, Crawford, D. H. G., Dejong, C. H. C. and Fawcett, J. (2017). Do macrophages play a role in the development of endotoxin-induced biliary injury in rats?. HOBOKEN: WILEY.

Characterizing and predicting the in vivo kinetics of mesenchymal stem cells and their secretome for the treatment of liver cirrhosis

Wang, H., Liang, X., Weijs, L., Brooks, A., Liu, X., Roberts, M. S. and Crawford, D. H. G. (2017). Characterizing and predicting the in vivo kinetics of mesenchymal stem cells and their secretome for the treatment of liver cirrhosis. Gastroenterological Society of Australia Australian Gastroenterology Week Precision Medicine in Gastroenterology, Gold Coast, Queensland, 20–22 Aug 2017. Hoboken, NJ United States: Wiley.

Iron blocks the secretion of apolipoprotein E in cultured human adipocytes

Britton, L. J., Bridle, K., Jaskowski, L. A., He, J., Ng, C., Ruelcke, J. E., Reiling, J., Santrampurwala, N., Hill, M. M., Whitehead, J. P., Subramaniam, V. N. and Crawford, D. H. G. (2017). Iron blocks the secretion of apolipoprotein E in cultured human adipocytes. Gastroenterological Society of Australia Australian Gastroenterology Week Precision Medicine in Gastroenterology , Gold Coast, QLD, Australia, 20–22 August 2017. Hoboken, NJ United States: Wiley-Blackwell Publishing.

Non-invasive assessment of the liver using imaging

Thorling (Thompson), Camilla, Wang, Haolu, Liu, Xin, Liang, Xiaowen, Crawford, Darrell H. G. and Roberts, Michael S. (2017). Non-invasive assessment of the liver using imaging. SPIE BioPhotonics Australasia Conference, Adelaide, SA, Australia, 17 - 19 October 2016. Bellingham, WA, United States: International Society for Optical Engineering. doi: 10.1117/12.2242883

Efficacy and safety of ombitasvir/paritaprevir/ritonavir and dasabuvir, with or without ribavirin, in adults treated with the regimen approved in Australia, Canada, New Zealand, and Switzerland

Gane, E., Strasser, S. I., Feld, J., Dufour, J. F., Crawford, D., Roberts, S., Satyanand, T., Kapoor, M., Larsen, L. and Podsadecki, T. (2016). Efficacy and safety of ombitasvir/paritaprevir/ritonavir and dasabuvir, with or without ribavirin, in adults treated with the regimen approved in Australia, Canada, New Zealand, and Switzerland. HOBOKEN: WILEY-BLACKWELL.

Evaluation of a bone morphogenetic protein 6 variant as a cause of iron loading

Mcdonald, C. J., Rishi, G., Ostini, L., Wallace, D. F., Crawford, D. H. G., Sia, H., Clark, P. and Subramaniam, V. N. (2016). Evaluation of a bone morphogenetic protein 6 variant as a cause of iron loading. Gastroenterological Society of Australia, Australian Gastroenterology Week 2016, Adelaide, SA Australia, 10-12 October 2016. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.

Liver disease in Vietnam veterans: a comparison of veterans with and without PTSD

Hlaing, P. M., Bridle, K. R., Jaskowski, L. A., Harvey, W. M. and Crawford, D. H. G. (2016). Liver disease in Vietnam veterans: a comparison of veterans with and without PTSD. Gastroenterological Society of Australia, Australian Gastroenterology Week 2016, Adelaide, South Australia, Australia, 10–12 October 2016. Hoboken, NJ United States: Wiley-Blackwell Publishing.

Population-based factors associated with early death after liver cancer diagnosis and resection in Queensland, Australia 1996-2011

Clark, P. J., O'Rourke, T. R., Fawcett, J., Stuart, K. A., Macdonald, G. A., Crawford, D. H., Leggett, B. A., Whiteman, D. C., Baade, P. A. and Valery, P. C. (2016). Population-based factors associated with early death after liver cancer diagnosis and resection in Queensland, Australia 1996-2011. EASL International Liver Congress, Barcelona, Spain, 13-17 April 2016. Amsterdam, Netherlands: Elsevier. doi: 10.1016/S0168-8278(16)00477-3

The application of normothermic machine perfusion to bench-test human donor livers

Reiling, J., Simpson, A., Bridle, K. R., Lockwood, D., Santrampurwala, N., Britton, L., Dejong, C. H. C., Crawford, D. H. G. and Fawcett, J. (2016). The application of normothermic machine perfusion to bench-test human donor livers. Gastroenterological Society of Australia, Australian Gastroenterology Week 2016, Adelaide, South Australia, Australia, 10–12 October 2016. Hoboken, NJ United States: Wiley-Blackwell Publishing.

Using multiphoton fluorescence lifetime imaging to characterize liver damage and fluorescein disposition in liver in vivo

Thorling, Camilla A., Studier, Hauke, Crawford, Darrell H. G. and Roberts, Michael S. (2016). Using multiphoton fluorescence lifetime imaging to characterize liver damage and fluorescein disposition in liver in vivo. Multiphoton Microscopy in the Biomedical Sciences XVI, San Francisco, CA, United States, 14-16 February 2016. Bellingham, WA, United States: S P I E - International Society for Optical Engineering. doi: 10.1117/12.2235828

A blood-flow limited physiologically based kinetic model to characterize and predict the biological fate of mesenchymal stem cells in vivo

Wang, H., Liang, X., Endo-Munoz, L., Weijs, L., Liu, X., Crawford, D. and Roberts, M. (2015). A blood-flow limited physiologically based kinetic model to characterize and predict the biological fate of mesenchymal stem cells in vivo. Gastro 2015 GESA‐AGW And WGO International Congress, Gastroenterological Society Of Australia Australian Gastroenterology Week 2015 - World Congress Of Gastroenterology, , Brisbane, Queensland, Australia, 28 September‐2 October 2015. Richmond, VIC Australia: Wiley.

A physiologically based kinetic model to characterize and predict the biological fate of circulating tumor cells in vivo

Wang, H., Liang, X., Thorling, C., Xu, Z. P., Crawford, D., Liu, X. and Roberts, M. (2015). A physiologically based kinetic model to characterize and predict the biological fate of circulating tumor cells in vivo. European Cancer Congress, Vienna, Austria, 2015. Hoboken, NJ United States: Wiley. doi: 10.1016/S0959-8049(15)30013-7

Free fatty acid treatment reduces BMP6 signalling in AML12 hepatocytes

Santrampurwala, N., Bridle, K. R., Reiling, J., Britton, L. J., Jaskowski, L. A., Subramaniam, V. N. and Crawford, D. H. G. (2015). Free fatty acid treatment reduces BMP6 signalling in AML12 hepatocytes. Gastro 2015 GESA-AGW and WGO International Congress, Brisbane, Queensland, Australia, 28 September-2 October 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13087

Next-generation sequencing: application of a novel platform to the analysis of atypical iron disorders

Mcdonald, C. J., Ostini, L., Wallace, D. F., Lyons, A., Crawford, D. H. G. and Subramaniam, V. N. (2015). Next-generation sequencing: application of a novel platform to the analysis of atypical iron disorders. Gastro 2015 GESA‐AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 | World Congress of Gastroenterology, Brisbane, QLD, Australia, 28 September - 2 October 2015. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia.

Pre-treatment with TIMP-3 prevents the development of biliary injury in an LPS enhanced ischaemia-reperfusion animal model

Reiling, J., Bridle, K., Campbell, C., Santrampurwala, N., Britton, L., Cohen, A., Crawford, D., Dejong, C. and Fawcett, J. (2015). Pre-treatment with TIMP-3 prevents the development of biliary injury in an LPS enhanced ischaemia-reperfusion animal model. World Congress of Gastroenterology, Brisbane, Queensland, Australia, 28 September-2 October, 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13087

Serum adipokines in response to venesection in patients with non-alcoholic fatty liver disease

Britton, L., Bridle, K., Reiling, J., Santrampurwala, N., Wockner, L., Ching, H., Subramaniam, V., Crawford, D. and Adams, L. (2015). Serum adipokines in response to venesection in patients with non-alcoholic fatty liver disease. Gastro 2015 GESA-AGW and WGO International Congress, Brisbane, Queensland, Australia, 28 September-2 October 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.13087

Hepatic microRNA expression is altered in a murine model of iron and fat co-mediated liver injury

Mcdonald, C. J., Yuan, Y., Santrampurwala, N., Crawford, D. H. G. and Subramaniam, V. N. (2014). Hepatic microRNA expression is altered in a murine model of iron and fat co-mediated liver injury. HOBOKEN: WILEY-BLACKWELL. doi: 10.1111/jgh.12736_5

The potential role of lipopolysaccharides in the development of biliary injury in an animal partial liver ischemia model

Reiling, J., Bridle, K. R., Santrampurwala, N., Britton, L. J., Crawford, D. H. G., Dejong, C. H. C. and Fawcett, J. (2014). The potential role of lipopolysaccharides in the development of biliary injury in an animal partial liver ischemia model. HOBOKEN: WILEY-BLACKWELL. doi: 10.1111/jgh.12736_8

ABT-450/r/Ombitasvir plus Dasabuvir With or Without Ribavirin in HCV Genotype 1-infected Patients with History of Depression or Bipolar Disorder: Pooled Analysis of Efficacy and Safety in Phase 3 Trials

Nelson, David R., Reddy, K. Rajender, Di Bisceglie, Adrian M., Ferenci, Peter, Crawford, Darrell H., Stauber, Rudolf E., Yakovlev, Alexey A., de Ledinghen, Victor, Hinrichsen, Holger, Bernstein, David Eric, de Knegt, Robert J., Hassanein, Tarek, Norris, Suzanne, Xiong, Junyuan J., McGovern, Barbara H. and Agarwal, Kosh (2014). ABT-450/r/Ombitasvir plus Dasabuvir With or Without Ribavirin in HCV Genotype 1-infected Patients with History of Depression or Bipolar Disorder: Pooled Analysis of Efficacy and Safety in Phase 3 Trials. 65th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, Massachusetts, 7-11 November 2014 . Hoboken, NJ, United States: John Wiley & Sons.

Safety of ABT-450/r/Ombitasvir plus Dasabuvir With or Without Ribavirin in HCV Genotype 1-infected Patients >= 65 Years of Age: Results From Phase 2 and 3 Trials

Flamm, Steven L., Gane, Edward J., DuFour, Jean-Francois J., Rustgi, Vinod, Bain, Vincent G., Crawford, Darrell H., Andreone, Pietro, Hassanein, Tarek, Mazur, Wlodzimierz W., Lovell, Sandra S., Da Silva-Tillmann, Barbara, Shulman, Nancy, Puoti, Massimo, Box, Terry D. and Jacobson, Ira M. (2014). Safety of ABT-450/r/Ombitasvir plus Dasabuvir With or Without Ribavirin in HCV Genotype 1-infected Patients >= 65 Years of Age: Results From Phase 2 and 3 Trials. 65th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, Massachusetts, 7-11 November 2014. Hoboken, NJ, United States: John Wiley & Sons.

Successful ex-vivo normothermic oxygenated machine perfusion of human donor livers

Reiling, J., Lockwood, D. S. R., Simpson, A. H., Campbell, C. M., Bridle, K. R., Santrampurwala, N., Britton, L. J., Crawford, D. H. G., Dejong, C. H. C. and Fawcett, J. (2014). Successful ex-vivo normothermic oxygenated machine perfusion of human donor livers. 65th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA, United States, 7 - 11 November 2014. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia.

Administration of an iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe-/- mice

Wilkinson, Ashley S., Bridle, Kim, Britton, Laurence, Jaskowski, Lesley, Fletcher, Linda M., Subramaniam, V. Nathan and Crawford, Darrell H. (2013). Administration of an iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe-/- mice. 64th Annual Meeting and Postgraduate Course of the American Association for the Study of Liver Diseases, Washington, DC, United States, 1 - 5 November 2013. Hoboken, NJ, United States: John Wiley & Sons.

An iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe(-/-) mice

Wilkinson, A. S., Bridle, K. R., Britton, L. J., Jaskowski, L. A., Fletcher, L. M., Subramaniam, V. N. and Crawford, D. H. G. (2013). An iron-deficient diet attenuates diet-induced hepatic steatosis in HFE-associated non-alcoholic fatty liver disease using Hfe(-/-) mice. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

Heterozygous Deletion of the Hfe Gene Contributes to Hepatic Iron Loading But Not Steatosis in Mice Fed a High Fat Diet

Britton, Laurence, Jaskowski, Lesley, Wilkinson, Ashley, Bridle, Kim, Subramaniam, Nathan and Crawford, Darrell (2013). Heterozygous Deletion of the Hfe Gene Contributes to Hepatic Iron Loading But Not Steatosis in Mice Fed a High Fat Diet. 5th Meeting of the International BioIron Society, University College London UK, 14 - 18 May 2013. Hoboken, NJ United States: John Wiley and Sons, Inc. doi: 10.1002/ajh.23453

Heterozygous Hfe (haemochromatosis) gene deletion contributes to hepatic iron loading but not steatosis in mice fed a high fat diet

Britton, L., Jaskowski, L., Wilkinson, A., Bridle, K., Subramaniam, N. and Crawford, D. (2013). Heterozygous Hfe (haemochromatosis) gene deletion contributes to hepatic iron loading but not steatosis in mice fed a high fat diet. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

Hfe-associated steatohepatitis: Expression profiling and identifying the molecular basis of liver injury

Santrampurwala, N., Bridle, K. R., Heritage, M. L., Jaskowski, L. A., Wilkinson, A. S., Subramaniam, V. N. and Crawford, D. H. G. (2013). Hfe-associated steatohepatitis: Expression profiling and identifying the molecular basis of liver injury. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

Impaired iron uptake in Mdr2(-/-) mice results in hepatic iron deficiency: implications for patients with cholestatic liver injury

Sobbe, A. L., Frazer, D. M., Bridle, K. R., Jaskowski, L. A., Anderson, G. J., Subramaniam, V. N. and Crawford, D. H. (2013). Impaired iron uptake in Mdr2(-/-) mice results in hepatic iron deficiency: implications for patients with cholestatic liver injury. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, 7 - 9 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

Interleukin-28B rs12979860 C allele is protective against advanced fibrosis in chronic he[atotos C genotype 1 infection: analysis of the Australasian Chariot Study Cohort

Kitson, M. T., Dore, G. J., George, J., Button, P., McCaughan, G. W., Crawford, D. H., Sievert, W., Weltman, M. D., Cheng, W. S. and Roberts, S. K. (2013). Interleukin-28B rs12979860 C allele is protective against advanced fibrosis in chronic he[atotos C genotype 1 infection: analysis of the Australasian Chariot Study Cohort. International Liver Congress / 48th Annual Meeting of the European Association for the Study of the Liver (EASL), Amsterdam Netherlands, 24-28 April 2013. Amsterdam, The Netherlands: Elsevier BV. doi: 10.1016/S0168-8278(13)60468-7

Isolated Hepatic Iron Deficiency Despite Abundant Systemic Iron in Mdr2-/- Mice: Integrity of the Biliary Transport System Is Important in Liver Iron Homeostasis

Sobbe, Amy, Frazer, David, Bridle, Kim, Jaskowski, Lesley, Ostini, Lesa, de Guzman, Erika, Santrampurwala, Nishreen, Anderson, Gregory, Subramaniam, V. Nathan and Crawford, Darrell (2013). Isolated Hepatic Iron Deficiency Despite Abundant Systemic Iron in Mdr2-/- Mice: Integrity of the Biliary Transport System Is Important in Liver Iron Homeostasis. 5th Meeting of the International BioIron Society, University College London UK, 14 - 18 May 2013. Hoboken, NJ United States: John Wiley and Sons, Inc. doi: 10.1002/ajh.23453

New genetic complexity underlying atypical iron disorders

McDonald, C. J., Wallace, D. F., Crawford, D. H. and Subramaniam, V. N. (2013). New genetic complexity underlying atypical iron disorders. Australian Gastroenterology Week 2013, Melbourne, Australia, 7-9 October 2013. Richmond Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12365

The impact of phlebotomy in non-alcoholic fatty liver disease: interim results of a randomized controlled trial

Adams, Leon, House, Michael J., St Pierre, Timothy G., Crawford, Darrell H., Stuart, Katherine A., Ching, Helena, Kava, Jenny, Webb, Malcolm and Olynyk, John K. (2013). The impact of phlebotomy in non-alcoholic fatty liver disease: interim results of a randomized controlled trial. 64th Annual Meeting and Postgraduate Course of the American Association for the Study of Liver Diseases, Washington Dc, 01 - 05 November, 2013. Hoboken, NJ United States: John Wiley and Sons, Inc.. doi: 10.1002/hep.26849

Application of next-generation sequencing technology to diagnosis of genetic iron disorders

McDonald, Cameron, Wallace, Daniel, Crawford, Darrell H. and Subramaniam, Nathan (2012). Application of next-generation sequencing technology to diagnosis of genetic iron disorders. Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/j.1440-1746.2011.07251.x

Curcumin and vitamin E combination treatment reduces the severity of disease in a diet-induced mouse model of NAFLD

Wilkinson, Ashley S., Heritage, Mandy L., Jaskowski, Lesley A., Britton, Laurence J., Tan, Terrence C., Clouston, Andrew, Bridle, Kim, Macdonald, Graeme A., Anderson, Gregory, Fletcher, Linda M., Subramaniam, Nathan and Crawford, Darrell H. (2012). Curcumin and vitamin E combination treatment reduces the severity of disease in a diet-induced mouse model of NAFLD. Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, Vic., Australia: Wiley-Blackwell Publishing. doi: 10.1111/j.1440-1746.2011.07251.x

Deferasirox does not exhibit antifibrotic activity when administered to Mdr2-/- mice

Sobbe, Amy, Bridle, Kim, de Guzman, Cloe Erika, Santrampurwala, Nishreen, Subramaniam, Nathan and Crawford, Darrell H. (2012). Deferasirox does not exhibit antifibrotic activity when administered to Mdr2-/- mice. Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, Vic., Australia: Wiley-Blackwell Publishing. doi: 10.1111/j.1440-1746.2011.07251.x

Iron Toxicity Impairs Autophagy and Promotes ER Stress in Obesity and Alcohol-Induced Fibrosing Steatohepatitis

Tan, Terrence C., Crawford, Darrell H., Jaskowski, Lesley, Santrampurwala, Nishreen, Heritage, Mandy, Subramaniam, V. Nathan, Clouston, Andrew D., Crane, Denis I., Anderson, Gregory J. and Fletcher, Linda M. (2012). Iron Toxicity Impairs Autophagy and Promotes ER Stress in Obesity and Alcohol-Induced Fibrosing Steatohepatitis. 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), Boston, MA, United States, 9-13 November 2012. Hoboken, NJ, United States: John Wiley and Sons. doi: 10.1002/hep.26040

Iron toxicity impairs autophagy and promotes ER stress in obesity and alcohol-induced fibrosing steatohepatitis

Tan, Terrence C., Crawford, Darrell H., Jaskowski, Lesley A., Murphy, Therese L., Santrampurwala, Nishreen, Heritage, Mandy L., Subramaniam, Nathan, Clouston, Andrew, Crane, Denis I., Anderson, Gregory and Fletcher, Linda M. (2012). Iron toxicity impairs autophagy and promotes ER stress in obesity and alcohol-induced fibrosing steatohepatitis. Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, Vic., Australia: Wiley-Blackwell Publishing. doi: 10.1111/j.1440-1746.2011.07251.x

The progression of NAFLD to NASH in a mouse model of Hfe(-/-)- associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E

Heritage, Mandy, Jaskowski, Lesley, Wilkinson, Ashley S., Britton, Laurence, Tan, Terrence C., Clouston, Andrew D., Bridle, Kim, Anderson, Gregory J., Macdonald, Graeme A., Fletcher, Linda M., Subramaniam, V. Nathan and Crawford, Darrell H. (2012). The progression of NAFLD to NASH in a mouse model of Hfe(-/-)- associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E. 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), Boston MA., United States, 9-13 November 2012. Hoboken, NJ United States: John Wiley and Sons. doi: 10.1002/hep.26040

The progression of NAFLD to NASH in a mouse model of Hfe(-/-)-associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E

Heritage, Mandy L., Wilkinson, Ashley S., Jaskowski, Lesley A., Britton, Laurence J., Tan, Terrence C., Bridle, Kim, Clouston, Andrew, Anderson, Gregory, Fletcher, Linda M., Macdonald, Graeme A., Subramaniam, Nathan and Crawford, Darrell H. (2012). The progression of NAFLD to NASH in a mouse model of Hfe(-/-)-associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E. Abstracts of the Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/j.1440-1746.2011.07251.x

Vitamin D Status Is Associated with Complete Evr But Not Svr in Chronic Hepatitis C Genotype 1 Infection: Analysis of the Australasian Chariot Study Cohort

Kitson, MT, Dore, GJ, Button, P, McCaughan, G, Crawford, D, Sievert, W, Weltman, M, Cheng, W, Roberts, SK and Chariot (2012). Vitamin D Status Is Associated with Complete Evr But Not Svr in Chronic Hepatitis C Genotype 1 Infection: Analysis of the Australasian Chariot Study Cohort. 47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Barcelona Spain, Apr 18-22, 2012. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(12)61138-6

Vitamin D status and liver histology in chronic hepatitis C genotype 1 infection: Analysis of the Australasian chariot study cohort

Kitson, M. T., Dore, G. J., Button, P., McCaughan, G., Crawford, D., Sievert, W., Weltman, M., Cheng, W., Roberts, S. K. and Chariot (2012). Vitamin D status and liver histology in chronic hepatitis C genotype 1 infection: Analysis of the Australasian chariot study cohort. 47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Barcelona Spain, Apr 18-22, 2012. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(12)60913-1

Altered lipid metabolism in HFE-knockout mice promotes severe NAFLD and early fibrosis

Tan, Terrence C. H., Crawford, Darrell H. G., Jaskowski, Lesley A., Murphy, Therese M., Heritage, Mandy L., Subramaniam, V. Nathan, Clouston, Andrew D., Anderson, Gregory J. and Fletcher, Linda M. (2011). Altered lipid metabolism in HFE-knockout mice promotes severe NAFLD and early fibrosis. Australian Gastroenterology Week 2011, Brisbane, Australia, 12-15 September 2011. MALDEN: WILEY-BLACKWELL.

Early On-Treatment Plasma Ribavirin Concentrations Are Associated with On-Treatment Anaemia and Treatment Outcome in Chronic Hepatitis C Genotype 1 Patients

Ali, R. J., Roberts, S. K., Ray, J., Sievert, W., McCaughan, G., Weltman, M., Crawford, D., Cheng, W., Rawlinson, W., Thommes, J., Rizkalla, B., Yoshihara, M., Dore, G. J., Matthews, G. V. and Chariot Study Grp (2011). Early On-Treatment Plasma Ribavirin Concentrations Are Associated with On-Treatment Anaemia and Treatment Outcome in Chronic Hepatitis C Genotype 1 Patients. 46th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Berlin Germany, 2011. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(11)60403-0

Evolution of hepatic fibrosis in Mdr2(-/-): Distinct temporal expression of fibrogenic mediators

Marbach, J., Sobbe, A. L., Jaskowski, L., De Guzman, C. E., Santrampurwala, N., Bridle, K. R. and Crawford, D. H. (2011). Evolution of hepatic fibrosis in Mdr2(-/-): Distinct temporal expression of fibrogenic mediators. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing.

Hepatic regeneration is not impaired in the Mdr2(-/-) mouse model of cholestasis

Hsu, L., Sobbe, A. L., Jaskowski, L., De Guzman, C. E., Santrampurwala, N., Bridle, K. R. and Crawford, D. H. (2011). Hepatic regeneration is not impaired in the Mdr2(-/-) mouse model of cholestasis. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing.

Hepatocellular carcinoma in an Australian tertiary hospital: No evidence of detection at an earlier stage over the past 10-years

Woodward, A. J., Miller, L. J., Fawcett, J., Crawford, D. H. G. and Stuart, K. A. (2011). Hepatocellular carcinoma in an Australian tertiary hospital: No evidence of detection at an earlier stage over the past 10-years. Unknown, unknown, unknown. MALDEN: WILEY-BLACKWELL.

Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice suggests a liver-specific alteration in iron metabolism

Sobbe, A. L., Bridle, K. R., Jaskowski, L. A., Ostini, L., De Guzman, C. E., Santrampurwala, N., Subramaniam, V. N., Fletcher, L. M. and Crawford, D. H. (2011). Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice suggests a liver-specific alteration in iron metabolism. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing.

Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice: Integrity of the bile transport system is important in normal liver iron homeostasis

Sobbe, A., Bridle, K., Jaskowski, L., Ostini, L., de Guzman, C. E., Santrampurwala, N., Subramaniam, V. N., Fletcher, L. M. and Crawford, D. H. (2011). Isolated hepatic iron deficiency despite abundant systemic iron in Mdr2(-/-) mice: Integrity of the bile transport system is important in normal liver iron homeostasis. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco, CA, United States, 4-8 November 2011. Malden MA United States: Wiley-Blackwell Publishing.

Lack of efficacy of rapamycin as an antifibrotic agent in the Mdr2(-/-) model of liver fibrosis

Bridle, K. R., Sobbe, A., Jaskowski, L., De Guzman, C. E., Santrampurwala, N., Fletcher, L. and Crawford, D. H. (2011). Lack of efficacy of rapamycin as an antifibrotic agent in the Mdr2(-/-) model of liver fibrosis. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing.

The Altered Expression of Iron Metabolism Genes in Models of Liver Injury Suggests Iron Deficiency in Cholestasis and Inappropriate Regulation of Hepcidin in Hepatocellular Cirrhosis

Heritage, M., Stuart, K. A., Bridle, K., Murphy, T. L., Sobbe, A., Jaskowski, L., Ostini, L., Subramaniam, V. N., Fletcher, L. M. and Crawford, D. H. (2011). The Altered Expression of Iron Metabolism Genes in Models of Liver Injury Suggests Iron Deficiency in Cholestasis and Inappropriate Regulation of Hepcidin in Hepatocellular Cirrhosis. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco, CA, United States, 4-8 November 2011. Malden MA United States: Wiley-Blackwell Publishing.

The altered expression of iron metabolism genes in models of liver injury suggests iron deficiency in cholestasis and inappropriate regulation of hepcidin in hepatocellular cirrhosis

Heritage, M. L., Stuart, K. A., Bridle, K. R., Murphy, T. L., Sobbe, A. L., Jaskowski, L. A., Ostini, L., Subramaniam, V. N., Fletcher, L. M. and Crawford, D. H. G. (2011). The altered expression of iron metabolism genes in models of liver injury suggests iron deficiency in cholestasis and inappropriate regulation of hepcidin in hepatocellular cirrhosis. Australian Gastroenterology Week 2011, Brisbane, Australia, 12–15 September 2011. Malden MA United States: Wiley-Blackwell Publishing.

The protective effects of corn-oil diet against alcohol and iron-induced hepatotoxicity in a mouse model of hemochromatosis

Tan, T., Crawford, D. H., Jaskowski, L., Murphy, T. L., Subramaniam, V. N. and Fletcher, L. M. (2011). The protective effects of corn-oil diet against alcohol and iron-induced hepatotoxicity in a mouse model of hemochromatosis. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL. doi: 10.1002/hep.24666

Altered expression of iron-regualtory genes in an animal model of cholestasis

Sobbe, A. L., Bridle, K.R., Fletcher, L. and Crawford, D, H. G. (2010). Altered expression of iron-regualtory genes in an animal model of cholestasis. Australian Gastroenterology Week 2010, Gold Coast, QLD, Australia, 20-23 October 2010. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2010.06450.x

Efficacy of tenofovir disoproxil fumarate treatment in patients with a suboptimal response to adefovir dipivoxil

Sievert, W., George, J., Strasser, S. I., Crawford, D., Heathcote, E. J., Marcellin, P., Elsome, A. M., Sorbel, J. and Rousseau, F. (2010). Efficacy of tenofovir disoproxil fumarate treatment in patients with a suboptimal response to adefovir dipivoxil. unknown, unknown, unknown. MALDEN: WILEY-BLACKWELL PUBLISHING, INC.

HBsAg kinetics of decay and baseline characteristics of HBeAg-positive patients with chronic hepatitis B following 3 years of tenofovir disoproxil fumarate (TDF) treatment

George, J., Gane, E. J., Sievert, W. S., Desmond, P. A., Crawford, D., Roberts, S. K., Strasser, S. I., Heathcote, E. J., Marcellin, P., Sorbel, J. and Rousseau, F. (2010). HBsAg kinetics of decay and baseline characteristics of HBeAg-positive patients with chronic hepatitis B following 3 years of tenofovir disoproxil fumarate (TDF) treatment. unknown, unknown, unknown. MALDEN: WILEY-BLACKWELL PUBLISHING, INC.

Non-Svr to peginterferon Alfa-2a therapy and ribavirin is strongly predicted by baseline factors and week 8 on-treatment viral load in Hcv genotype (gt) 1 patients: New insights from cart analysis of the chariot study

Roberts, S. K., Ferenci, P., Yoshihara, M., Crawford, D. H., Sieverf, W., McCaughan, G. W., Cheng, W., Weltman, M., Rawlinson, W. D., McCloud, P. I., Rizkalla, B. and Dore, G. J. (2010). Non-Svr to peginterferon Alfa-2a therapy and ribavirin is strongly predicted by baseline factors and week 8 on-treatment viral load in Hcv genotype (gt) 1 patients: New insights from cart analysis of the chariot study. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston, MA, United States, 29 Oct-2 Nov, 2010. MALDEN: WILEY-BLACKWELL.

Serum ferritin: An independent predictor of mortality in patients awaiting liver transplantation in a cohort and validation study of patients from Australia and North America

Walker, N. M., Stuart, K. A., Ryan, R. J., Desai, S., Saab, S., Nicol, J. A., Fletcher, L. M. and Crawford, D. H. G. (2010). Serum ferritin: An independent predictor of mortality in patients awaiting liver transplantation in a cohort and validation study of patients from Australia and North America. 45th Annual Meeting of the European-Association-for-the-Study-of-Liver, Vienna, Austria, April 14-18 2010. Amsterdam, Netherlands: Elsevier. doi: 10.1016/S0168-8278(10)60465-5

Serum hepcidin profiles in patients with advanced liver cirrhosis: relationships with iron markers and disease severity

Tan, Tch, Fletcher, L.M., Franklin, M.E., Taylor, P.J. and Crawford, D.H.G. (2010). Serum hepcidin profiles in patients with advanced liver cirrhosis: relationships with iron markers and disease severity. Australian Gastroenterology Week 2010, Gold Coast, Queensland, Australia, 20 - 23 October 2010. Richmond, Vic., Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2010.06451.x

Advanced fibrosis in genotype 1 HCV infected patients receiving antiviral therapy is associated with virologic relapse independent of rapid (RVR) and early (EVR) virologic response

McCaughan, G. W., Roberts, S. K., Weltman, M., Crawford, D. H., Sievert, W., Cheng, W., Rawlinson, W., Yoshihara, M., McCloud, P. I., Rizkalla, B. and Dore, G. J. (2009). Advanced fibrosis in genotype 1 HCV infected patients receiving antiviral therapy is associated with virologic relapse independent of rapid (RVR) and early (EVR) virologic response. 60th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston, MA, U.S.A., 30 October - 3 November 2009. HOBOKEN: JOHN WILEY & SONS INC. doi: 10.1002/hep.23307

Alcohol withdrawal is associated with a rebound increase in hepcidin expression: further evidence for an alcohol/hepcidin interaction

Tan, T. C. H., Heritage, M., Jaskowski, L. A., Murphy, T. L., Crawford, D. H. G. and Fletcher, L. M. (2009). Alcohol withdrawal is associated with a rebound increase in hepcidin expression: further evidence for an alcohol/hepcidin interaction. Australia & New Zealand Medical & Surgical Gastrointestinal Week 2009, Sydney, NSW, Australia, 21-24 October 2009. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2009.06055.x

Baseline and ontreatment predictors of svr to peginterferon alfa-2a therapy and ribavirin in hcv genotype (GT) 1 treatment naive patients: New insights from the chariot study

Weltman, M, Dore, GJ, Sievert, W, McCaughan, GW, Crawford, DH, Cheng, W, Rawlinson, W, Yashihara, M, McCloud, PI, Rizkalla, B and Roberts, SK (2009). Baseline and ontreatment predictors of svr to peginterferon alfa-2a therapy and ribavirin in hcv genotype (GT) 1 treatment naive patients: New insights from the chariot study. 60th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston MA, OCT 30-NOV 03, 2009. HOBOKEN: JOHN WILEY & SONS INC.

Efficacy and safety of peginterferon alfa-2A 360 mu g/week in combination with ribavirin in hepatitis C genotype 1 patients with cirrhosis : Analysis from the chariot study

Cheng, W. S. C., Roberts, S., Weltman, M., Crawford, D. H. G., Sievert, W., McCaughan, G., Rawlinson, W., Desmond, P., Yoshihara, M., Rizkalla, B., DePamphilis, J., Marks, P. and Dore, G. J. (2009). Efficacy and safety of peginterferon alfa-2A 360 mu g/week in combination with ribavirin in hepatitis C genotype 1 patients with cirrhosis : Analysis from the chariot study. 44th Annual Meeting of the European-Association-for-the-Study-of-the-Liver, Copenhagen, Denmark, 22-26 April 2009. Copenhagan, Denmark: Elsevier. doi: 10.1016/S0168-8278(09)60603-6

Expression of fibrogenic genes does not differentiate patients with rapid and non-rapid progression post liver transplant for hepatitis C

Sobbe, A.L., Bridle, K.R., Morgan, M.L., Lipka, G., Fletcher, L. and Crawford, D.H.G. (2009). Expression of fibrogenic genes does not differentiate patients with rapid and non-rapid progression post liver transplant for hepatitis C. Australia & New Zealand Medical & Surgical Gastrointestinal Week 2009, Sydney Convention & Exhibition Centre, Sydney, NSW, Australia, 21-24 October 2009. Carlton South, Vic.: Blackwell Publishing Asia.

High-dose peginterferon alfa-2A (40KD) induction therapy and standard ribavirin enhances early but not sustained virological responses in HCV genotype 1 patients: Final chariot study results

Roberts, S., Weltman, M., Crawford, D. H. G., Cheng, W. S. C., Sievert, W., McCaughan, G., Desmond, P., Rawlinson, W., Marks, P., Yoshihara, M., Rizkalla, B., DePamphilis, J. and Dore, G. J. (2009). High-dose peginterferon alfa-2A (40KD) induction therapy and standard ribavirin enhances early but not sustained virological responses in HCV genotype 1 patients: Final chariot study results. 44th Annual Meeting of the European Association for the Study of the Liver, Copenhagen, Denmark, 22-26 April 2009. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(09)60126-4

Impact of low-level hepatitis C viraemia at week 24 on HCV treatment response in genotype 1 patients

Baleriola, C., Rawlinson, W., Chaverot, S., Stelzer-Braid, S., Yoshihara, M., Rizkalla, B., Dubois, D., Sievert, W., McCaughan, G., Crawford, D. H. G., Weltman, M., Cheng, W. S. C., Dore, G. J. and Roberts, S. (2009). Impact of low-level hepatitis C viraemia at week 24 on HCV treatment response in genotype 1 patients. 44th Annual Meeting of the European-Association-for-the-Study-of-the-Liver, Copenhagen, Denmark, 22-26 April 2009. Copenhagan, Denmark: Elsevier. doi: 10.1016/S0168-8278(09)60600-0

PEGINTERFERON ALFA-2A (40KD) (PEGIFN alpha 2A) HAS A WIDE SAFETY MARGIN IN COMBINATION WITH RIBAVIRIN (RBV) 1000/1200 MG/DAY IN PATIENTS INFECTED WITH HCV GENOTYPE 1: POOLED ANALYSIS OF DATA FROM FOUR RANDOMIZED MULTICENTER STUDIES

Marcellin, P, Jensen, DM, Roberts, SK, Hadziyannis, SJ, Dore, GJ, Diago, M, Weltman, M, McCaughan, GW, Cheng, W, Crawford, DH, Sievert, W, Rawlinson, W, Solsky, J, Tietz, A and Rizzetto, M (2009). PEGINTERFERON ALFA-2A (40KD) (PEGIFN alpha 2A) HAS A WIDE SAFETY MARGIN IN COMBINATION WITH RIBAVIRIN (RBV) 1000/1200 MG/DAY IN PATIENTS INFECTED WITH HCV GENOTYPE 1: POOLED ANALYSIS OF DATA FROM FOUR RANDOMIZED MULTICENTER STUDIES. 60th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston MA, OCT 30-NOV 03, 2009. HOBOKEN: JOHN WILEY & SONS INC.

Reimbursement policies in Asia-Pacific for chronic Hepatitis B

Lim, Seng Gee, Amarapurkar, Deepak N., Chan, Henry Lik-Yuen, Crawford, Darrell H., Gane, Edward J, Han, Kwang-Hyub, Ishaque, Shamsuddin M., Jafri, Syed M., Jia, Jidong, Kao, Jia-Horng, Lesmana, Laurentius A., Mizokami, Masashi, Mohamed, Rosmawati, Pham, Pham Hoang, Piratvisuth, Teerha, Sarin, Shiv K., Sollarno, Jose D., Yokosuka, Osamu and Lok, Anna S. (2009). Reimbursement policies in Asia-Pacific for chronic Hepatitis B. 60th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA, U.S.A., 30 October - 3 November 2009. Hoboken, NJ, U.S.A.: John Wiley & Sons. doi: 10.1002/hep.23303

SIGNIFICANT HEMOGLOBIN (HB) DECLINE DURING PEGYLATED INTERFERON AND RIBAVIRIN THERAPY IN HCV GENOTYPE 1 IS ASSOCIATED WITH SUSTAINED VIROLOGIC RESPONSE (SVR): AN ANALYSIS FROM THE CHARIOT STUDY

Sievert, W, Dore, GJ, McCaughan, GW, Yoshihara, M, Crawford, DH, Cheng, W, Weltman, M, Rawlinson, W, Rizkalla, B, McCloud, PI and Roberts, SK (2009). SIGNIFICANT HEMOGLOBIN (HB) DECLINE DURING PEGYLATED INTERFERON AND RIBAVIRIN THERAPY IN HCV GENOTYPE 1 IS ASSOCIATED WITH SUSTAINED VIROLOGIC RESPONSE (SVR): AN ANALYSIS FROM THE CHARIOT STUDY. 60th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston MA, OCT 30-NOV 03, 2009. HOBOKEN: JOHN WILEY & SONS INC.

The antifibrotic effect of low dose rapamycin is diminished in Mdr2-/- when administered to animals with advanced hepatic fibrosis

Sobbe, AL, Bridle, KR and Crawford, DHG (2009). The antifibrotic effect of low dose rapamycin is diminished in Mdr2-/- when administered to animals with advanced hepatic fibrosis. Australia & New Zealand Medical & Surgical Gastrointestinal Week 2009, Sydney, Australia, 21-24 October 2009. MALDEN: WILEY-BLACKWELL PUBLISHING, INC.

Baseline factors associated with rapid and early virological responses in HCV genotype 1 patients treated with induction dosing of pegylated interferon: The CHARIOT study

Crawford, D. H. G., Roberts, S., Weltman, M., Cheng, W. S. C., Sievert, W., McCaughan, G., Desmond, P., Alston, A. W., DePamphilis, J., Marks, P. and Dore, G. J. (2008). Baseline factors associated with rapid and early virological responses in HCV genotype 1 patients treated with induction dosing of pegylated interferon: The CHARIOT study. 43rd Annual Meeting of the European Association for the Study of the Liver, Milan, Italy, 23-27 April 2008. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(08)60781-3

Hepcidin regulation in response to alcohol consumption: evidence for an alcohol-induced hypoxic response

Heritage, M. L., Jaskowski, L. A., Bridle, K. R., Murphy, T. L., Anderson, G. J., Crawford, D. H. and Fletcher, L. M. (2008). Hepcidin regulation in response to alcohol consumption: evidence for an alcohol-induced hypoxic response. Australian Gastroenterology Week, Brisbane, Qld, Australia, 22-25 October, 2008. Carlton South, Vic, Australia: Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2008.05613.x

Hepcidin regulation in wild-type and HFE-/mice in response to alcohol consumption: Evidence for an alcohol-induced hypoxic response

Fletcher, L. M., Heritage, M. L., Murphy, T. L., Bridle, K. R., Anderson, G. J. and Crawford, D. H. (2008). Hepcidin regulation in wild-type and HFE-/mice in response to alcohol consumption: Evidence for an alcohol-induced hypoxic response. 43rd Annual Meeting of the European Association for the Study of the Liver, Milan, Italy, 23-27 April, 2008. Copenhagen, Denmark: Elsevier. doi: 10.1016/S0168-8278(08)60888-0

Hepcidin regulation in wild-type and Hfe(-/-) mice in response to alcohol consumption: Evidence for an alcohol-induced hypoxic response

FletcherLM, Heritage, ML, MurphyTL, BridleKR, AndersonGJ and CrawfordDH (2008). Hepcidin regulation in wild-type and Hfe(-/-) mice in response to alcohol consumption: Evidence for an alcohol-induced hypoxic response. 43rd Annual Meeting of the European-Association-for-the-Study-of-the-Liver, Milan ITALY, APR 23-27, 2008. doi: 10.1016/S0168-8278(08)60888-0

Multiple pathways to hepatic fibrosis are inhibited by rapamycin

Bridle, K. R., Sobbe, A. L., Fletcher, L. M., Clouston, A. D. and Crawford, D. H. G. (2008). Multiple pathways to hepatic fibrosis are inhibited by rapamycin. Australian Gastroenterology Week 2008, Brisbane, Qld, Australia, 22-25 October 2008. Carlton South, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2008.05613.x

Obesity is linked with increased clot strength and impaired fibrinolysis in nonalcoholic fatty liver disease

Hickman, I. J., Sullivan, C. M., Flight, S., Campbell, C., Crawford, D. H., Masci, P. P., O'Moore-Sullivan, T. M., Prins, J. B. and Macdonald, G. A. (2008). Obesity is linked with increased clot strength and impaired fibrinolysis in nonalcoholic fatty liver disease. 16th European Congress on Obesity, Geneva, Switzerland, 14-17 May 2008. LONDON: NATURE PUBLISHING GROUP.

Rapamycin as an inhibitor of hepatic fibrosis: relevance to whole blood levels

Popa, C., Bridle, K. R., Morgan, M. L., Clouston, A. D., Fletcher, L. M. and Crawford, D. H. G. (2008). Rapamycin as an inhibitor of hepatic fibrosis: relevance to whole blood levels. 43rd Annual Meeting of the European Association for the Study of the Liver, Milan, Italy, 23-27 April, 2008. Ireland: Elsevier. doi: 10.1016/S0168-8278(08)60467-5

Serum ferritin concentration predicts mortality and adverse liver events in patients with cirrhosis listed for liver transplantation

Walker, N. M., Ryan, R. J., Fletcher, L. M., Nicol, J., Stuart, K. A. and Crawford, D. H. (2008). Serum ferritin concentration predicts mortality and adverse liver events in patients with cirrhosis listed for liver transplantation. Australian Gastroenterology Week, Brisbane, Australia, 22–25 October 2008. MALDEN: WILEY-BLACKWELL PUBLISHING, INC.

Serum ferritin concentration predicts mortality and adverse liver-related clinical events in patients with cirrhosis listed for liver transplantation

Crawford, D. H., Walkerl, N. M., Stuart, K. A., Fletcher, L. M., Ryon, R. J. and Nicol, J. (2008). Serum ferritin concentration predicts mortality and adverse liver-related clinical events in patients with cirrhosis listed for liver transplantation. 59th Annual Meeting of the American Association for the Study of Liver Diseases, San Francisco, CA, United States, 31 October-4 November 2008. HOBOKEN: WILEY-BLACKWELL PUBLISHING, INC.

Serum hyaluronic acid with serum ferritin accurately predicts cirrhosis and reduces the need for liver biopsy in C282Y hemochromatosis

Crawford, Darrell H., Murphy, Therese L., Ramm, Louise E., Fletcher, Linda M., Clouston, Andrew D., Anderson, Gregory J., Subramaniam, V. Nathan, Powell, Lawrie W. and Ramm, Grant A. (2008). Serum hyaluronic acid with serum ferritin accurately predicts cirrhosis and reduces the need for liver biopsy in C282Y hemochromatosis. The Liver Meeting 2008: 59th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), San Francisco, CA, U.S.A., 31 October-4 November 2008. Hoboken, NJ, U.S.A.: John Wiley & Sons. doi: 10.1002/hep.22641

Serum hyaluronic acid with serum ferritin accurately predicts cirrhosis and reduces the need for liver biopsy in C282Y hemochromatosis

Crawford, D. H. G., Murphy, T. L., Ramm, L. E., Fletcher, L. M., Clouston, A. D., Anderson, G. J., Subramaniam, V. N., Powell, L. W. and Ramm, G. A. (2008). Serum hyaluronic acid with serum ferritin accurately predicts cirrhosis and reduces the need for liver biopsy in C282Y hemochromatosis. AGW 2008: Australian Gastroenterology Week 08, Brisbane, QLD, Australia, 22-25 October 2008. MALDEN: WILEY-BLACKWELL PUBLISHING, INC. doi: 10.1111/j.1440-1746.2008.05613.x

Alcohol consumption further modulates hepcidin gene expression in an animal model of hemochromatosis

Heritage, M. L., Murphy, T. L., Popa, C., Bridle, K. R., Anderson, G. J., Crawford, D. H. G. and Fletcher, L. M. (2007). Alcohol consumption further modulates hepcidin gene expression in an animal model of hemochromatosis. Australian Gastroenterology Week 2007, Perth, Australia, 24–27 October 2007. Melbourne, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2007.05161.x

Alcohol consumption further modulates hepcidin gene expression in an animal model of hemochromatosis

Fletcher, L. M., Heritage, M. L., Murphy, T. L., Popa, C., Bridle, K. R., Anderson, G. J. and Crawford, D. H. (2007). Alcohol consumption further modulates hepcidin gene expression in an animal model of hemochromatosis. 58th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, Massachusetts, U.S.A., 1-6 November 2007. U.S.A.: Wiley InterScience. doi: 10.1002/hep.22022

Does iron play a role in the pathogenesis and phenotype of hepatocellular carcinoma in patients with cirrhosis?

Ryan, R., Fletcher, L., Jones, D., Stuart, K. and Crawford, D. (2007). Does iron play a role in the pathogenesis and phenotype of hepatocellular carcinoma in patients with cirrhosis?. 2007 International BioIron Society Meeting, Kyoto, Japan, 1-6 April 2007. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/ajh.20964

Hepciden gene expression is further suppressed in Hfe-/- mice following chronic ethanol consumption

Fletcher, L. M., Heritage, M. L., Murphy, T. L., Bridle, K. R., Anderson, G. J. and Crawford, D. H. G. (2007). Hepciden gene expression is further suppressed in Hfe-/- mice following chronic ethanol consumption. 2007 International BioIron Society Meeting, Kyoto, Japan, 1-6 April, 2007. New York: Wiley-LISS. doi: 10.1002/ajh.20964

Rapamycin as an anti-fibrotic agent

Popa, C., Bridle, K. R., Morgan, M. L., Robinson, M. W., Fletcher, L. M. and Crawford, D. H. (2007). Rapamycin as an anti-fibrotic agent. Australian Gastroenterology Week, Perth, Australia, 24-27 October 2007. Australia. doi: 10.1111/j.1440-1746.2007.05161.x

Post liver transplantation disease recurrence: influence of matrix degradation proteins

Bridle, K. R., Murphy, T. L., Fletcher, L. M. and Crawford, D. H. G. (2006). Post liver transplantation disease recurrence: influence of matrix degradation proteins. Australian Gastroenterology Week 2006, Adelaide, South Australia, 11-14 October, 2006. Carlton South, Vic. Australia: Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2006.04689.x

Serum adiponectin is increased in HFE-/- mice fed alcohol

Bridle, K. R., Murphy, T. L., Anderson, G. J., Macdonald, G. A., Crawford, D. H. G. and Fletcher, L. M. (2006). Serum adiponectin is increased in HFE-/- mice fed alcohol. Australian Gastroenterology Week 2006, Adelaide, South Australia, 11-14 October, 2006. Carlton South, Vic. Australia: Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2006.04689.x

Very low dose rapamycin : In vitro evidence for its use as an antifibrotic agent

Morgan, M. L., Bridle, K. R., Fletcher, L. M. and Crawford, D. H. G. (2006). Very low dose rapamycin : In vitro evidence for its use as an antifibrotic agent. Australian Gastroenterology Week, Adelaide, SA, Australia, 11-14 October 2006. Richmond, Vic., Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2006.04689.x

Very low dose rapamycin: in vitro evidence for its use as an antifibrotic agent

Morgan, M. L., Bridle, K. R., Fletcher, L. M. and Crawford, D. H. G. (2006). Very low dose rapamycin: in vitro evidence for its use as an antifibrotic agent. Australian Gastroenterology Week 2006, Adelaide, South Australia, 11-14 October, 2006. Carlton South, Vic. Australia: Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2006.04689.x

Von Willebrand factor expression in relation to cirrhosis development in a rat model of fibrogenesis

Bridle, K. R., Patella, S., Tchongue, J., Fletcher, L. M., Sievert, W. and Crawford, D. H. G. (2006). Von Willebrand factor expression in relation to cirrhosis development in a rat model of fibrogenesis. Australian Gastroenterology Week 2006, Adelaide, South Australia, 11-14 October, 2006. Carlton South, Vic. Australia: Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2006.04689.x

Von Willebrand factor expression in relation to cirrhosis development in a rat model of fibrogenesis

Bridle, K. R., Patella, S., Tchongue, J., Fletcher, L. M., Sievert, W. and Crawford, D. H. G. (2006). Von Willebrand factor expression in relation to cirrhosis development in a rat model of fibrogenesis. Australian Gastroenterology Week, Adelaide, Australia, 11–14 October 2006. Oxford United Kingdom: Wiley.

Expression of the iron regulatory peptide hepcidin is reduced in patients with chronic liver disease

Anderson, Greg, Frazer, David M., Bridle, Kim R., Macdonald, Graeme A., Smith, Jeffrey L., Turlin, Bruno, Subramaniam, Nathan, Crawford, Darrell H., Powell, Lawrie W. and Ramm, Grant A. (2005). Expression of the iron regulatory peptide hepcidin is reduced in patients with chronic liver disease. 47th Annual Meeting of the American Society of Hematology, Atlanta, Georgia, USA, 10-13 December, 2005. Washington, D.C., USA: American Society of Hematology.

Hepatic fibrosis but not cirrhosis in hemochromatosis is reversed by iron removal by phlebotomy therapy.

Powell, LW, Dixon, JL, Anderson, GA, Subramaniam, VN, Lincoln, DJ, Fletcher, LM, Crawford, DH, Searle, JW and Ramm, GA (2005). Hepatic fibrosis but not cirrhosis in hemochromatosis is reversed by iron removal by phlebotomy therapy.. 56th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, San Francisco CA, NOV 11-15, 2005. HOBOKEN: JOHN WILEY & SONS INC.

Rapamycin, but not cyclosporine A or tacrolimus, reduces hepatic stellate cell activation: implications for post-transplant fibrogenesis

Bridle, K. R., Robinson, M. W., Fletcher, L. M. and Crawford, D. H. (2005). Rapamycin, but not cyclosporine A or tacrolimus, reduces hepatic stellate cell activation: implications for post-transplant fibrogenesis. Australian Gastroenterology Week 2005, Brisbane, Qld, Australia, 19-22 October, 2005. Carlton South, Vic. Australia: Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2005.04091_4.x

Unexplained late centrilobular hepatitis after liver transplantation - Relationship to autoimmune hepatitis and GST-T1 mismatch

Clouston, A., Campbell, C., Lynch, S., Jonsson, J., Balderson, G., Barrie, H. and Crawford, D. (2005). Unexplained late centrilobular hepatitis after liver transplantation - Relationship to autoimmune hepatitis and GST-T1 mismatch. 56th Annual Meeting of the American Association for the Study of Liver Diseases, San Francisco, CA, United States, 11-15 November 2005. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/hep.20924

Alcohol-induced down-regulation of hepcidin mRNA expression is mediated by oxidative stress

Bridle, K. R., Murphy, T., Walters, M., Crawford, D. H. G. and Fletcher, L. M. (2004). Alcohol-induced down-regulation of hepcidin mRNA expression is mediated by oxidative stress. Australian Gastroenterology Week 2004, Brisbane Convention Centre, Brisbane Qld, Australia, 4-8 October, 2004. Carlton South, Vic. Australia: Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2004.3615_3..x

Alcohol-induced downregulation of hepcidin mRNA expression is mediated by oxidative stress

Bridle, Kim, Crawford, Darrell, Fletcher, Linda, Murphy, Therese and Walters, Margaret (2004). Alcohol-induced downregulation of hepcidin mRNA expression is mediated by oxidative stress. The Liver Meeting 2004: 55th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA, U.S.A., 29 October-2 November 2004. Hoboken, NJ, U.S.A: John Wiley & Sons. doi: 10.1002/hep.1840400508

Alcohol-induced downregulation of hepcidin mRNA expression is mediated by oxidative stress

Bridle, K., Murphy, T., Walters, M., Crawford, D. and Fletcher, L. (2004). Alcohol-induced downregulation of hepcidin mRNA expression is mediated by oxidative stress. 55th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), Boston MA, United States, Oct 29 - Nov 02 2004. Hoboken, NJ United States: John Wiley & Sons.

Factors affecting the gene expression of hepcidin in chronic viral hepatitis C

Bridle, K. R., Fletcher, L. M., Jonsson, J. R., Richardson, M. M., Clouston, A. D., Powell, E. E. and Crawford, D. H. G. (2004). Factors affecting the gene expression of hepcidin in chronic viral hepatitis C. Australian Gastroenterology Week 2004, Brisbane Convention Centre, Brisbane, Qld Australia, 4-8 October, 2004. Carlton South, Vic. Australia: Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2004.3615_3..x

The penetrance of HFE-associated hemochromatosis as assessed by clinical evaluation and liver biopsy in subjects identified by health checks, family screening or population screening

Powell, L. W., Dixon, J. L., Ramm, G. A., Anderson, G. J., Subramaniam, V. N., Purdie, D. M., Hewett, D. G., Searle, J. W., Fletcher, L. M., Crawford, D. H., Rodgers, H., Khoo, T. L., Cavanaugh, J. A. and Bassett, M. L. (2004). The penetrance of HFE-associated hemochromatosis as assessed by clinical evaluation and liver biopsy in subjects identified by health checks, family screening or population screening. 55th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), Boston MA, 29 October - 2 November 2004. HOBOKEN: JOHN WILEY & SONS INC.

A comparison of the hepatic extraction of transferrin-bound and non-transferrin bound iron in an animal model of haemolytic anemia

Bridle, K. R., Fletcher, L. M., Murphy, T., Walters, M., Hung, D., Chang, P., Siebert, G., Roberts, M. and Crawford, D. H. G. (2003). A comparison of the hepatic extraction of transferrin-bound and non-transferrin bound iron in an animal model of haemolytic anemia. 54th Annual Meeting of the American Association for the Study of Liver Disease, Boston, Massachusetts, USA, 24-28 October 2003. Carlton South, Vic.: Blackwell Publishing Asia. doi: 10.1046/j.1440-1746.18.s2.5.x

A comparison of the hepatic extraction of transferrin-bound and non-transferrin bound iron in an animal model of hemolytic anemia

Fletcher,Linda, Bridle, Kim, Murphy, Therese, Walters, Margaret, Hung, Daniel, Chang, Ping, Siebert, Gerhard, Roberts, Michael and Crawford, Darrell (2003). A comparison of the hepatic extraction of transferrin-bound and non-transferrin bound iron in an animal model of hemolytic anemia. 54th Annual Meeting of the American Association for the Study of Liver Disease, Boston, Massachusetts, USA, 24 - 28 October, 2003. Hoboken, NJ, U.S.A: Wiley Interscience. doi: 10.1002/hep.1840380508

Dark adaptation improves with intramuscular vitamin A in patients awaiting liver transplantation

Abbott-Johnson, W. J., Abiad, G., Kerlin, P., Cuneo, R. C., Crawford, D. H., Ash, A., Clague, A. and Coroneo, M. (2003). Dark adaptation improves with intramuscular vitamin A in patients awaiting liver transplantation. 21st Annual Scientific Meeting of the Transplantation Societyd, Canberra, 9-11 April, 2003. Australia: Blackwell Publishing Asia.

Failure of hepcidin upregulation in HFE-associated haemochromatosis implicates the liver in the regulation of body iron homeostasis

Bridle, K. R., Frazer, D. M., Wilkins, S. J., Dixon, J. L., Millard, K. N., Crawford, D. H. G., Subramaniam, V. N., Powell, L. W., Anderson, G. J. and Ramm , G. A. (2003). Failure of hepcidin upregulation in HFE-associated haemochromatosis implicates the liver in the regulation of body iron homeostasis. Australian Gastroenterology Week, Cairns, Australia, 7-10 October 2003. Carlton South, Vic., Australia: Blackwell Publishing Asia. doi: 10.1046/j.1440-1746.18.s2.5.x

Hepcidin expression is down-regulated in alcohol-fed rats: A possible pathogenic factor in alcohol related hepatic siderosis

Cheung, T. K., Fletcher, L., Bridle, K., Murphy, T. and Crawford, D. (2003). Hepcidin expression is down-regulated in alcohol-fed rats: A possible pathogenic factor in alcohol related hepatic siderosis. 54th Annual Meeting of the American-Association-for-the-Study-of-Liver-Disease, Boston MA, United States, Oct 24-28, 2003. Hoboken, NJ United States: John Wiley & Sons.

Hepcidin expression is down-regulated in alcohol-fed rats: A possible pathogenic factor in alcohol related hepatic siderosis.

Bridle, Kim, Cheung, Ting Kin, Crawford, Darrell, Fletcher, Linda and Murphy, Therese (2003). Hepcidin expression is down-regulated in alcohol-fed rats: A possible pathogenic factor in alcohol related hepatic siderosis.. The Liver Meeting 2003: 54th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA, U.S.A., 25-28 October 2003. 0270-9139 (print); 1527-3350 (electronic): John Wiley & Sons. doi: 10.1002/hep.1840380508

Model for end-stage liver disease (MELD) score: Is it useful in predicting outcome following cadeveric liver transplant?

Meade, B. J., Yeung, S., Balderson, G.A., Crawford, D. H. and Lynch, S. V. (2003). Model for end-stage liver disease (MELD) score: Is it useful in predicting outcome following cadeveric liver transplant?. 21st Annual Scientific Meeting, Canberra, 9-11 April 2003. Australia: Blackwell Publishing Asia.

Rates of iron accumulation in untreated subjects homozygous for the C282Y hemochromatosis mutation: Relevance to disease penetrance

Powell, L. W., Dixon, J. L., Hewett, D. G., Purdie, D. M., Ramm, G. A., Anderson, G. J., Subramaniam, N., Fletcher, L. M., Crawford, D. H., Cavanaugh, J. A. and Bassett, M. L. (2003). Rates of iron accumulation in untreated subjects homozygous for the C282Y hemochromatosis mutation: Relevance to disease penetrance. 54th Annual Meeting of the American Association for the Study of Liver Disease, Boston, MA, United States, 24-28 October 2003. PHILADELPHIA: W B SAUNDERS CO.

Reduced hepcidin expression in alcohol-fed rats may be a contributing factor in alcoholic hepatic siderosis

Cheung, T. K., Fletcher, L. M., Bridle, K. R., Murphy, T. L. and Crawford, D. H. G. (2003). Reduced hepcidin expression in alcohol-fed rats may be a contributing factor in alcoholic hepatic siderosis. Australian Gastroenterology Week 2003, Cairns, QLD, Australia, 7-10 Ocrober, 2003. Carlton South, Vic. Australia: Blackwell Publishing Asia. doi: 10.1046/j.1440-1746.18.s2.5.x

The clinical relevance of compound heterozygosity for the hemochromatosis mutations (C282Y/H63D)

Hewett, D. G.., Dixon, J. L., Purdie, D. M., Ramm, G. A., Anderson, G. J., Subramaniam, N., Fletcher, L. M., Crawford, D. H., Cavanaugh, J. A., Bassett, M. L. and Powell, L. W. (2003). The clinical relevance of compound heterozygosity for the hemochromatosis mutations (C282Y/H63D). 54th Annual Meeting of the American Association for the Study of Liver Disease, Boston, M.A. USA, 24-28 October 2003. PHILADELPHIA: W B SAUNDERS CO.

Duodenal expression of iron transport genes in untreated hemochromatosis subjects.

Stuart, K, Anderson, G, Frazer, D, Powell, L, McCullen, M, Fletcher, L and Crawford, D (2002). Duodenal expression of iron transport genes in untreated hemochromatosis subjects.. 53rd Annual Meeting of the Association-for-the-Study-of-Liver-Diseases (AASLD), Boston Massachusetts, Nov 01-05, 2002. PHILADELPHIA: W B SAUNDERS CO.

Hereditary hemochromatosis and liver transplantation: Implications for patient survival, graft function and the pathogenesis of hereditary hemochromatosis.

Crawford, D, Hubscher, S, Stuart, K, McCaughan, G, Gane, E, Angus, P, Jeffrey, G, Kerlin, P, Powell, L, Fletcher, L and Elias, E (2002). Hereditary hemochromatosis and liver transplantation: Implications for patient survival, graft function and the pathogenesis of hereditary hemochromatosis.. 53rd Annual Meeting of the Association-for-the-Study-of-Liver-Diseases (AASLD), Boston Massachusetts, Nov 01-05, 2002. PHILADELPHIA: W B SAUNDERS CO.

Phenotypic expression of hfe-associated hemochromatosis in C282Y homozygous relatives: Implications for screening.

Powell, L, Dixon, JL, Ramm, G, Anderson, G, Subramaniam, N, Fletcher, L, Crawford, D, Cavanaugh, J and Bassett, M (2002). Phenotypic expression of hfe-associated hemochromatosis in C282Y homozygous relatives: Implications for screening.. 53rd Annual Meeting of the Association-for-the-Study-of-Liver-Diseases (AASLD), Boston Massachusetts, Nov 01-05, 2002. PHILADELPHIA: W B SAUNDERS CO.

Centrilobular hepatitis with elevated autoantibody titers after liver transplantation: autoimmune hepatitis or a form of rejection?

Clouston, A.D., McCullen, M., Fawcett, J. and Crawford, D.H. (2002). Centrilobular hepatitis with elevated autoantibody titers after liver transplantation: autoimmune hepatitis or a form of rejection?. 53rd Annual Meeting of the Association for the Study of Liver Diseases (AASLD), Boston, MA, United States, 1-5 November 2002. Hoboken, NJ, United States: John Wiley & Sons.

The effects of vitamin B12 on hepatitis C virus replication

Whiting, P.W., Gowans, E.J., Sloots, T.P., Mackay, I.M., Tillack, S., Harrison, M., Beller, E.M. and Crawford, D.H.G. (2002). The effects of vitamin B12 on hepatitis C virus replication. Digestive Disease Week and the 103rd Annual Meeting of the American Gastroenterological Association. Digestive Disease Week and the 103rd Annual Meeting of the American Gastroenterological Association, San Francisco, CA, United States, 19-22 May 2002. Maryland Heights, MO, United States: W.B. Saunders.

Expression of intestinal iron transport proteins in animal models of cirrhosis: relationship to reduced hepatic iron concentrations in cholestasis

Stuart, K.A., Fletcher, L.M., Anderson, G.J., Frazer, D.M., Murphy, T.M. and Crawford, D.H. (2001). Expression of intestinal iron transport proteins in animal models of cirrhosis: relationship to reduced hepatic iron concentrations in cholestasis. 52th Annual Meeting of the American Association for the Study of Liver Diseases, Dallas, TX, United States, 9-13 November 2001. Hoboken, NJ, United States: John Wiley & Sons.

Hepatic expression of iron transporters in patients with hemochromatosis or hepatitis C virus infection

Brindle, K.R., Frazer, D.M., Crawford, D.H. and Ramm, G.A. (2001). Hepatic expression of iron transporters in patients with hemochromatosis or hepatitis C virus infection. 52th Annual Meeting of the American Association for the Study of Liver Diseases, Dallas, TX, United States, 9-13 November 2001. Hoboken, NJ, United States: John Wiley & Sons.

Intestinal iron transporter expression in liver disease

Stuart, K.A., Frazer, D.M., Purdie, D.M., Fletcher, L.M., Anderson, G.J. and Crawford, D.H. (2001). Intestinal iron transporter expression in liver disease. 102nd Annual Meeting of the American Gastroenterological Association, Atlanta, GA, United States, 20-23 May 2001. Maryland Heights, MO, United States: W.B. Saunders. doi: 10.1016/S0016-5085(08)83376-8

Non-HFE related haemochromatosis in Australia

Wallace, D. F., Dixon, J. L., Stephenson, P., Searle, J. W., Fletcher, L. M., Crawford, D. H., Subramaniam, V. N. and Powell, L. W. (2001). Non-HFE related haemochromatosis in Australia. 52th Annual Meeting of the American Association for the Study of Liver Diseases, Dallas, TX, United States, 9-13 November 2001. Hoboken, NJ, United States: John Wiley & Sons.

Outcome analysis of a hospital-based screening strategy for C282Y hereditary haemochromatosis (HHC)

McCullen, M., Fletcher, L.M., Powell, L.W., Roggeveen, J., Pink, A., Dimeski, G., Hickman, P. and Crawford, D.H. (2001). Outcome analysis of a hospital-based screening strategy for C282Y hereditary haemochromatosis (HHC). 52th Annual Meeting of the American Association for the Study of Liver Diseases, Dallas, TX, United States, 9-13 November 2001. Hoboken, NJ, United States: John Wiley & Sons.

Concordance of iron indices between family members within hemochromatosis families: further evidence that it additional modifying genes influence HFE expression in hemochromatosis

Whiting, P.W., Poos, J.F., Purdie, D.M., Powell, L.W., Fletcher, L.M. and Crawford, D.H. (2000). Concordance of iron indices between family members within hemochromatosis families: further evidence that it additional modifying genes influence HFE expression in hemochromatosis. 51st Annual Meeting American Association for the Study of Liver Disease, Dallas, TX, United States, 27 - 31 October 2000. Hoboken, NJ, United States: John Wiley & Sons.

Early detection of response to interferon treatment in chronic HCV

Butterworth, L. A., Cooksley, W. G. E., Crawford, D., D'Arcy, D., Dorrington, L., Garrett, L., Hourigan, K., Macdonald, G. and Walker, D. (2000). Early detection of response to interferon treatment in chronic HCV. 10th Int Symp on Viral Hepatitis and Liver Disease, Atlanta, USA, 9-13 April, 2000.

Effects of cobalamin on hepatitis C virus translation and replication

Cooksley, W. G. E., Crawford, D., Gowans, E. J., Harrison, M., Lott, W. B., Macdonald, G. and Sloots, T. (2000). Effects of cobalamin on hepatitis C virus translation and replication. Ann Mtg of American Assn for the Study of Liver Disease, Dallas, Texas, 27-31 Oct, 2000.

Effects of cobalamin on hepatitis C virus translation and replication

Crawford, D.H., Lott, W.B., Cooksley, G., HArrison, M., McDonald, G., Sloots, T. and Gowans, E.J. (2000). Effects of cobalamin on hepatitis C virus translation and replication. 51st Annual Meeting American Association for the Study of Liver Disease, Dallas, TX, United States, 27 - 31 October 2000. Hoboken, NJ, United States: John Wiley & Sons.

Expression of duodenal iron transporters in patients with cirrhosis

Stuart, K.A., Frazer, D.M., Fletcher, L.M., Anderson, G.J. and Crawford, D.H. (2000). Expression of duodenal iron transporters in patients with cirrhosis. 51st Annual Meeting American Association for the Study of Liver Disease, Dallas, TX, United States, 27 - 31 October 2000. Hoboken, NJ, United States: John Wiley & Sons.

Hepatic cirrhosis in hereditary hemochromatosis is seldom due soley to iron: evidence for a synergistic effect of alcohol and iron

Fletcher, L.L., Dixon, J.L., Powell, L.W. and Crawford, D.H. (2000). Hepatic cirrhosis in hereditary hemochromatosis is seldom due soley to iron: evidence for a synergistic effect of alcohol and iron. 51st Annual Meeting American Association for the Study of Liver Disease, Dallas, TX, United States, 27 - 31 October 2000. Hoboken, NJ, United States: John Wiley & Sons.

Lamivudine therapy for chronic hepatitis B patients receiving immunosuppression for non-hepatic diseases

Thomson, R.K., Koorey, D.J., Angus, P.W., Crawford, D.H. and McCaughan, G.W. (2000). Lamivudine therapy for chronic hepatitis B patients receiving immunosuppression for non-hepatic diseases. Annual Meeting of the British Society of Gastroenterology, Unknown, 2000. London, United Kingdom: B M J Group.

The role of cytokine gene polymorphisms in acute rejection after liver transplantation

Balderson, G. A., Clouston, A. D., Crawford, D. H., Edwards-Smith, C., Fawcett, J., Hong, C., Jonsson, J. R., Lynch, S. V., Pandeya, N., Powell, E., Purdie, D. M. and Stuart, K. A. (2000). The role of cytokine gene polymorphisms in acute rejection after liver transplantation. American Association for Study of Liver Disease, Dallas, U.S.A., 27-31 Oct, 2000. Orlando, U.S.A.: W. B. Saunders Co. Ltd..

The role of cytokine gene polymorphisms in acute rejection after liver transplantation

Jonsson, J. R., Cui, H., Powell, E., Pandeyer, N., Balderson, G. A., Clouston, A. D., Edwards-Smith, C., Stuart, K. A., Crawford, D. H., Fawcett, J., Lynch, S. V. and Purdie, D. M. (2000). The role of cytokine gene polymorphisms in acute rejection after liver transplantation. Australian Gastroenterology Week 2000, Hobart, Australia, 18-21 October, 2000. Melbourne: Blackwell Scientific.

The role of cytokine gene polymorphisms in acute rejection after liver transplantation

Hong, C., Powell, E. E., Balderson, G. A., Clouston, A. D., Purdie, D. M., Pandeya, N., Edwards-Smith, C. J., Stuart, K. A., Crawford, D. H., Fawcett, J., Lynch, S. V. and Jonsson, J. R. (2000). The role of cytokine gene polymorphisms in acute rejection after liver transplantation. -, -, -. PHILADELPHIA: W B SAUNDERS CO.

Automated measurement of unsaturated iron binding capcity is an effective screening strategy for C282Y homozygous hemochromatosis

Hickman, P. E., Hourigan, L. F., Powell, L. W. and Crawford, D. H. (1999). Automated measurement of unsaturated iron binding capcity is an effective screening strategy for C282Y homozygous hemochromatosis. Bioiron'99, Sorrento Palace, Sorrento - Naples, Italy, 23 - 28 May 1999. Italy: SGC.

Combination low dose hepatitis B immune globulin (HBIG) and lamivudine therapy provides effective prophylaxis against post transplant hepatitis B

Angus, P.W., Gane, E.J., Crawford, D.H. and McCaughan, G.W. (1999). Combination low dose hepatitis B immune globulin (HBIG) and lamivudine therapy provides effective prophylaxis against post transplant hepatitis B. 50th Annual Meeting American Association for the Study of Liver Disease, Dallas, TX, United States, 5-9 November 1999. Hoboken, NJ, United States: John Wiley & Sons.

Early detection of sustained responders to Interferon treatment

Butterworth, L. A., Cooksley, W. G. E., Crawford, D., D'Arcy, D., Dorrington, L., Hourigan, K. and Walker, D. (1999). Early detection of sustained responders to Interferon treatment. 3rd International Conference on Therapies for Viral Hepatitis, Ritz Carlton, Maui, Hawaii, 12-16 December, 1999. Atlanta, Georgia: Int. Medical Press.

Energy and amino acid supplements in a malnourished patients with cirrhosis: a randomised controlled trial

Sievert, W., Gibson, P.R., Colman, J.C., Kronborg, I., Crawford, D.H., Keogh, J., Nyulasi, I.B. and Strauss, B.J. (1999). Energy and amino acid supplements in a malnourished patients with cirrhosis: a randomised controlled trial. 50th Annual Meeting American Association for the Study of Liver Disease, Dallas, TX, United States, 5-9 November 1999. Hoboken, NJ, United States: John Wiley & Sons.

Hepatic iron overload not due to the C282Y mutation is associated with heavy iron loading in other organs

Fletcher, L. M., Summerville, L., Busfield, F., Bligh, J., Searle, J. W., Halliday, J. W., Powell, L. W. and Crawford, D. H. (1999). Hepatic iron overload not due to the C282Y mutation is associated with heavy iron loading in other organs. Bioiron'99, Sorrento Palace, Sorrento-Naples, Italy, 23 - 28 May, 1999. Italy: SGC.

Identification and characterisation of a receptor for transferrin on hepatic stellate cells: role in the transformation to myofibroblasts

Bridle, K., Blanch, N. L., Crawford, D. H. and Ramm, G. A. (1999). Identification and characterisation of a receptor for transferrin on hepatic stellate cells: role in the transformation to myofibroblasts. Australian Gastroenterology Week 1999, Brisbane, 4 - 8 Oct, 1999. Carlton, Vic: Blackwell Science Asia.

Identification and characterisation of the hepatic stellate cell transferrin receptor and influence of transferrin on hepatic stellate cell activation

Bridle, K., Stewart, N. L., Crawford, D. H., Anderson, G. and Ramm, G. A. (1999). Identification and characterisation of the hepatic stellate cell transferrin receptor and influence of transferrin on hepatic stellate cell activation. Bioiron'99, Sorrento Palace, Sorrento-Naples, Italy, 23 - 28 May 1999. Italy: SGC.

Iron overload in end-stage liver disease: Relationship to disease severity and post-transplant outcome

Stuart, K. A., Fletcher, L. M., Clouston, A., Purdie, D. M., Lynch, S. V., Kerlin, P. and Crawford, D. H. (1999). Iron overload in end-stage liver disease: Relationship to disease severity and post-transplant outcome. Australian Gastroenterology Week 1999, Brisbane, 4-8 October, 1999. Carlton, Vic: Blackwell Science.

Lamivudine therapy for patients with chronic hepatitis B receiving immunosuppression for non-hepatic diseases

Thomson, R.K., Koorey, D.J., Angus, P.W., Crawford, D.H. and McCaughan, G.W. (1999). Lamivudine therapy for patients with chronic hepatitis B receiving immunosuppression for non-hepatic diseases. 50th Annual Meeting American Association for the Study of Liver Disease, Dallas, TX, United States, 5-9 November 1999. Hoboken, NJ, United States: John Wiley & Sons.

Mayo risk score and child-pugh score are predictors of resource utilisation following orthotopic liver transplantation for primary biliary cirrhosis

Gilroy, R., Lynch, S. V., Strong, R. W., Kerlin, P., Balderson, G. A. and Crawford, D. H. (1999). Mayo risk score and child-pugh score are predictors of resource utilisation following orthotopic liver transplantation for primary biliary cirrhosis. Australian Gastroenterology Week 1999, Brisbane, 4-8 Oct, 1999. Carlton, Vic.: Blackwell Science.

Non-C282Y hepatic iron overload is associated with heavy iron loading in other organs

Crawford, D.H., Fletcher, L.M., Summerville, L., Busfield, F., Bligh, J., Searle, J.W., Halliday, J.W. and Powell, L.W. (1999). Non-C282Y hepatic iron overload is associated with heavy iron loading in other organs. 50th Annual Meeting American Association for the Study of Liver Disease, Dallas, TX, United States, 5-9 November 1999. Hoboken, NJ, United States: John Wiley & Sons.

Outcome of liver transplantation in patients with increase hepatic iron stores depends upon severity of liver disease but not degree of hepatic iron loading

Stuart, K.A., Fletcher, L.M., Kerlin, P., Purdie, D., Lynch, S.V. and Crawford, D.H. (1999). Outcome of liver transplantation in patients with increase hepatic iron stores depends upon severity of liver disease but not degree of hepatic iron loading. 50th Annual Meeting American Association for the Study of Liver Disease, Dallas, TX, United States, 5-9 November 1999. Hoboken, NJ, United States: John Wiley & Sons.

Serum collagen type IV and hyaluronic acid as markers of hepatic fibrosis in patients with haemochromatosis and other chronic liver diseases

Ramm, G. A., Murphy, T. L., Fanning, P. A., Clouston, A. D., George, D. K., Fletcher, L. M., Anderson, G., Powell, L. W. and Crawford, D. H. (1999). Serum collagen type IV and hyaluronic acid as markers of hepatic fibrosis in patients with haemochromatosis and other chronic liver diseases. Bioiron'99, Sorrento Palace, Sorrento - Naples, Italy, 23 - 28 May 1999. Italy: SGC.

Serum hyaluronic acid and collagen type IV as markers of hepatic fibrosis in patients with haemochromatosis and other chronic liver diseases

Ramm, G. A., Murphy, T. L., Fanning, P. A., Clouston, A. D., George, D. K., Fletcher, L. M., Anderson, G., Powell, L. W. and Crawford, D. H. (1999). Serum hyaluronic acid and collagen type IV as markers of hepatic fibrosis in patients with haemochromatosis and other chronic liver diseases. American Assoc. for the Study of Liver Diseases 50th Annual Meeting, Dallas, Texas, USA, 5 - 9 Nov, 1999. USA: W B Saunders Co..

Serum hyaluronic acid and collagen type IV as markers of hepatic fibrosis in patients with haemochromatosis and other chronic liver diseases American Association for the Study of Liver Diseases (AASLD) 50th annual meeting. Texas, USA. November 5-9, 1999.

Ramm, G.A., Murphy, T.L., Fanning, P.A., Clouston, A.D., Anderson, G.J. and Crawford, D.H. (1999). Serum hyaluronic acid and collagen type IV as markers of hepatic fibrosis in patients with haemochromatosis and other chronic liver diseases American Association for the Study of Liver Diseases (AASLD) 50th annual meeting. Texas, USA. November 5-9, 1999.. 50th Annual Meeting American Association for the Study of Liver Disease, Dallas, TX, United States, 5-9 November 1999. Hoboken, NJ, United States: John Wiley & Sons.

Serum hyaluronic acid is a sensitive marker of both cirrhosis in haemochromatosis and liver injury in other chronic liver diseases

Ramm, G. A., Murphy, T. L., Fanning, P. A., Clouston, A. D., George, D. K., Fletcher, L. M., Anderson, G., Powell, L. W. and Crawford, D. H. (1999). Serum hyaluronic acid is a sensitive marker of both cirrhosis in haemochromatosis and liver injury in other chronic liver diseases. Australian Gastroenterology Week 1999, Brisbane, 4 - 8 October,1999. Carlton, Vic: Blackwell Science Asia.

Transplanation for primary cholangitis - the Queensland experience

Thomson, A., Steadman, C., Balderson, G. A., Bansal, A., Crawford, D. H. and Lynch, S. V. (1999). Transplanation for primary cholangitis - the Queensland experience. Australian Gastroenterology Week 1999, Brisbane Convention Cen., 4-8 Oct, 1999. Carlton, Vic.: Blackwell Science.

Automated measurement of unsaturated iron binding capacity allows a cost effective, ongoing strategy for screening for haemochromatosis

Hickman, P., Hourgian, L., Powell, L.W. and Crawford, D.H.G. (1998). Automated measurement of unsaturated iron binding capacity allows a cost effective, ongoing strategy for screening for haemochromatosis. 49th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 6-10 November 1998. Hoboken, NJ, United States: John Wiley & Sons.

Ferritin increases PKC-zeta expression in early rat hepatic stellate cell activation

Ramm, G.A., Coomer, J.M., Watters, D.J. and Crawford, D.H.G. (1998). Ferritin increases PKC-zeta expression in early rat hepatic stellate cell activation. 49th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 6-10 November 1998. Hoboken, NJ, United States: John Wiley & Sons.

The changing role of liver biopsy in hereditary haemochromatosis after the cloning of the HFE gene

Baker, E.R., Monk, C.D., Do, K.A., Fletcher, L.M., Crawford, D.H.G. and Powell, L.W. (1998). The changing role of liver biopsy in hereditary haemochromatosis after the cloning of the HFE gene. 49th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 6-10 November 1998. Hoboken, NJ, United States: John Wiley & Sons.

The contribution of inflammatory cells to iron-induced hepatic fibrogenesis in hemochromatosis

Bridle, K. R., Crawford, D. H. G., Smith, J. L., Fletcher, L. M., Walker, N. I. and Ramm, G. A. (1998). The contribution of inflammatory cells to iron-induced hepatic fibrogenesis in hemochromatosis. 49th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 6-10 November 1998. Hoboken, NJ, United States: John Wiley & Sons.

Association of the HFE C282Y mutation with porphyria cutanea tarda in Australian patients The 47th Annual Meeting of the American Society of Human Genetics was held in Baltimore, Maryland, October 28 to November 1, l997

Busfield, F., Stuart, K.A., Gibson, P.R., Butterworth, L., Cooksley, G., Powell, L.W., Jazwinska, E.C. and Crawford, D.H.G. (1997). Association of the HFE C282Y mutation with porphyria cutanea tarda in Australian patients The 47th Annual Meeting of the American Society of Human Genetics was held in Baltimore, Maryland, October 28 to November 1, l997. 47th Annual Meeting of the American Society of Human Genetics, Baltimore, MD, United States, 28 October -1 November 1997. Cambridge, MA, United States: Cell Press.

Contribution of parenchymal and non-parenchymal cells to hepatic fibrogenesis in biliary atresia

Ramm, G.A., Shepherd, R.W. and Crawford, D.H.G. (1997). Contribution of parenchymal and non-parenchymal cells to hepatic fibrogenesis in biliary atresia. 48th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 7-11 November 1997. Hoboken, NJ, United States: John Wiley & Sons.

Expression of HLA-linked haemochromatosis in homozygous and heterozygous subjects diagnosed according to the C282Y mutation evaluation of previous diagnostic criteria

Crawford, D.H.G., Jazwinska, E.C., Cullen, L.M. and Powell, L.W. (1997). Expression of HLA-linked haemochromatosis in homozygous and heterozygous subjects diagnosed according to the C282Y mutation evaluation of previous diagnostic criteria. 48th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 7-11 November 1997. Hoboken, NJ, United States: John Wiley & Sons.

In vivo hepatic activities of matrix metalloproteinases-2, 3 and 9 are increased in prefibrotic animal and human iron overload

George, D.K., Ramm, G.A., Bridle, K.R., Fletcher, L.M. and Crawford, D.H.G. (1997). In vivo hepatic activities of matrix metalloproteinases-2, 3 and 9 are increased in prefibrotic animal and human iron overload. 48th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 7-11 November 1997. Hoboken, NJ, United States: John Wiley & Sons.

Interferon-gamma but not transforming growth factor-beta gene expression is upregulated in liver tissue of patients with genetic hemochromatosis

Bridle, K.R., Crawford, D.H.G., Fletcher, L.M. and Ramm, G.A. (1997). Interferon-gamma but not transforming growth factor-beta gene expression is upregulated in liver tissue of patients with genetic hemochromatosis. 48th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 7-11 November 1997. Hoboken, NJ, United States: John Wiley & Sons.

Role of tissue ferritin in regulation of alpha-smooth muscle actin expression in hepatic stellate cells via PKC zeta and/or nitric oxide

Ramm, G.A., Piva, T.J., Garrone, B.M., Watters, D.J. and Crawford, D.H.G. (1997). Role of tissue ferritin in regulation of alpha-smooth muscle actin expression in hepatic stellate cells via PKC zeta and/or nitric oxide. 48th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 7-11 November 1997. Hoboken, NJ, United States: John Wiley & Sons.

The C282Y mutation in HFE is common in Australian patients and can act independently of HCV to precipitate porphyria cutanea tarda

Stuart, K.A., Busfield, F., Jazwinska, E.C., Gibson, P., Butterworth, L.A., Cooksley, W.G.E., Powell, L.W. and Crawford, D.H.G. (1997). The C282Y mutation in HFE is common in Australian patients and can act independently of HCV to precipitate porphyria cutanea tarda. 48th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 7-11 November 1997. Hoboken, NJ, United States: John Wiley & Sons.

The role of activated hepatic stellate cells in capsule formation in hepatocellular carcinoma and colorectal metastases to the liver

Ramm, G.A., Ooi, L. L. P. J., Gotley, D. C., Clouston, A. D., Bridle, K. R. and Crawford, D. H. G. (1997). The role of activated hepatic stellate cells in capsule formation in hepatocellular carcinoma and colorectal metastases to the liver. 8th International Symposium on the Cells of the Hepatic Sinusoid, Bordeaux, France, 1-5 September 1996. Leiden, Netherlands: Kupffer Cell Foundation.

Biliary decompression results in rapid reversal of procollagen alpha(1)(I) gene expression in experimental biliary fibrosis

Ramm, G.A., Crawford, D.H.G., Bridle, K.R., Britton, R.S. and Bacon, B.R. (1996). Biliary decompression results in rapid reversal of procollagen alpha(1)(I) gene expression in experimental biliary fibrosis. 47th Annual Meeting of the American Association for the Study of Liver Disease, Chicag, Il, United States, 8-12 November 1996. Hoboken, NJ, United States: John Wiley & Sons.

Enhanced hepatic lipid peroxidation in genetic hemochromatosis; reversal by phlebotomy

Houglum, K., Ramm, G.A., Crawford, D.H.G., Witztum, J., Powell, L.W. and Chojkier, M. (1996). Enhanced hepatic lipid peroxidation in genetic hemochromatosis; reversal by phlebotomy. 47th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 8-12 November 1996. Hoboken, NJ, United States: John Wiley & Sons.

Evidence for altered matrix metalloproteinase and TIMP-1 activity in genetic hemochromatosis

George, D.K., Ramm, G.A. and Crawford, D.H.G. (1996). Evidence for altered matrix metalloproteinase and TIMP-1 activity in genetic hemochromatosis. 47th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 8-12 November 1996. Hoboken, NJ, United States: John Wiley & Sons.

Correlation between hepatic stellate cell activation and hepatitis-C virus genotype, viral load and response to interferon therapy

Ramm, G.A., Gibbons, J.C., Butterworth, L.A., Crawford, D.H.G., Walker, N.I. and Cooksley, W.G.E. (1995). Correlation between hepatic stellate cell activation and hepatitis-C virus genotype, viral load and response to interferon therapy. 46th Annual Meeting of the American Association for the Study of Liver Disease, Orlando, FL, United States, 1995. Hoboken, NJ, United States: John Wiley & Sons.

Hepatic stellate cell activation in genetic hemochromatosis: lobular distribution, effect of increasing hepatic iron and response to phlebotomy

Ramm, G.A., Powell, L.W., Fletcher, L.M., Walker, N.I., Owen, L.G. and Crawford, D.H.G. (1995). Hepatic stellate cell activation in genetic hemochromatosis: lobular distribution, effect of increasing hepatic iron and response to phlebotomy. 46th Annual Meeting of the American Association for the Study of Liver Disease, Orlando, FL, United States, 1995. Hoboken, NJ, United States: John Wiley & Sons.

The D2 dopamine-receptor a1 allele: a risk factor in hepatitis-C infection

Cooksley, W.G.E., Crawford, D.H.G., Foley, P.F., Lawford, B.R., Franz, C.P., Ritchie, T. and Noble, E.P. (1995). The D2 dopamine-receptor a1 allele: a risk factor in hepatitis-C infection. 46th Annual Meeting of the American Association for the Study of Liver Disease, Orlando, FL, United States, 1995. Hoboken, NJ, United States: John Wiley & Sons.

The distribution of transferrin saturation in an asymptomatic Australian population: relevance to the early diagnosis of hemochromatosis Washington, from. December 1-5, 1995.

McLaren, C.E., McLachlan, G.J., Webb, S.J., Jazwinska, E.C., Crawford, D.H.G., Gordeuk, V.R., McLaren, G.D. and Powell, LW (1995). The distribution of transferrin saturation in an asymptomatic Australian population: relevance to the early diagnosis of hemochromatosis Washington, from. December 1-5, 1995.. 37th Annual Meeting of the American Society of Hematology, Seattle, WA, United States, 1-5 December 1995. Washington, DC, United States: American Society of Hematology.

Alcohol Does Not Play a Significant Role in Promoting Cirrhosis in Chronic Hepatitis-C - Analysis of 102 Patients

Selvey, LA, Srirajalingan, M, Crawford, D, Leggett, B and Cooksley, Wge (1994). Alcohol Does Not Play a Significant Role in Promoting Cirrhosis in Chronic Hepatitis-C - Analysis of 102 Patients. W B SAUNDERS CO.

Body-composition analysis in nonalcoholic cirrhosis

Crawford, D.H.G., Shepherd, R.W., Cui, T.C., Murphy, T.L., Cooksley, W.G.E., Halliday, J.W. and Powell, L.W. (1992). Body-composition analysis in nonalcoholic cirrhosis. 43rd Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 31 October - 3 November 1992. Hoboken, NJ, United States: John Wiley & Sons.

Changes in body composition following liver transplantation

Crawford, D.H.G., Murphy, T.L., Cooksley, W.G.E., Halliday, J.W. and Powell, L.W. (1992). Changes in body composition following liver transplantation. 43rd Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 31 October - 3 November 1992. Hoboken, NJ, United States: John Wiley & Sons.

Glomerular lesions in cirrhosis: relationship to post liver transplant renal failure

Crawford, D.H.G., Axelsen, R.A., Powell, L.W., Kerlin, P., Endre, Z.H., Baldersen, G.A., Strong, R.J., Lynch, S.V. and Fleming, S.J. (1991). Glomerular lesions in cirrhosis: relationship to post liver transplant renal failure. 42ndAnnual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 2-5 November 1991. Hoboken, NJ, United States: John Wiley & Sons.

Universal occurrence of renal abnormalities in patients receiving liver transplants

Fleming, S.J., Crawford, D.H.G., Axelsen, R.A., Lynch, S.V., Baldersen, G.A., Strong, R.J., Kerlin, P., Powell, L.W. and Endre, Z.H. (1991). Universal occurrence of renal abnormalities in patients receiving liver transplants. 27th Scientific Meeting of the Australian and New Zealand Society of Nephrology, Christchurch, New Zealand, 27 February - 1 March 1991. London, United Kingdom: Nature Publishing Group. doi: 10.1038/ki.1991.245

Changes in body water and its distribution in patients with compensated cirrhosis

Crawford, D.H.G., Cheng, W.S.C., Murphy, T.L., Cooksley, W.G.E., Halliday, J.W. and Powell, L.W. (1990). Changes in body water and its distribution in patients with compensated cirrhosis. 41st Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 3-6 November 1990. Hoboken, NJ, United States: John Wiley & Sons.

The effect of progressive parenchymal liver disease on body fat and body cell mass

Crawford, D.H.G., Cheng, W.S.C., Murphy, T.L., Cooksley, W.G.E., Halliday, J.W. and Powell, L.W. (1990). The effect of progressive parenchymal liver disease on body fat and body cell mass. 41st Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 3-6 November 1990. Hoboken, NJ, United States: John Wiley & Sons.

Steatohepatitis: comparison of alcoholic and non-alcoholic subjects with particular reference to portal-hypertension and hepatic complications

Crawford, D. H. G., Powell, E. E., Searle, J. and Powell, L. W. (1989). Steatohepatitis: comparison of alcoholic and non-alcoholic subjects with particular reference to portal-hypertension and hepatic complications. International Symposium on Portal Hypertension and Digestive Organs, Tokyo Japan, 25 February 1989. Richmond, VIC, Australia: Wiley-Blackwell Publishing.