Dr Alex Smith

Research Fellow in Glycotherapeutic

School of Chemical Engineering
Faculty of Engineering, Architecture and Information Technology


Dr. Alex Smith is a Research Fellow at UQ's School of Chemical Engineering. His interests are in understanding structure: function relationships between complex carbohydrates (such as heparan sulphate) and proteins, and how these interactions can inform the development of glycotherapeutic agents to treat a wide variety of injuries and diseases.

Research Interests

  • Heparan sulphate and other glycosaminoglycans
    Understanding structure: function relationships between complex carbohydrates such as heparan sulphate and the myriad of proteins to which heparan sulphate binds. Specifically, assessing interactions between heparan sulphate and proteins involved in wound healing, inflammation, cell survival, and differentiation.
  • Cell membrane engineering
    Developing novel strategies for cell membrane engineering using glycoconjugates to influence cell behaviour.
  • Glycotherapeutics
    Assessing the potential of using heparan sulphate and synthetic heparan sulphate mimetics in the treatment of numerous diseases, injuries, and as media additives in the expansion of therapeutically relevant cell types.


View all Publications


Featured Publications

Book Chapter

  • Huang, Mia L., Smith, Raymond A. A., Trieger, Greg W. and Godula, Kamil (2016). Glycocalyx remodeling with glycopolymer-based proteoglycan mimetics. Macro-glycoligands: methods and protocols. (pp. 207-224) edited by Xue-Long Sun. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-3130-9_17

Journal Article

Conference Publication