Dr Adam Hagg

Research Officer

Faculty of Medicine

Overview

Publications

  • Sartori, Roberta, Hagg, Adam, Zampieri, Sandra, Armani, Andrea, Winbanks, Catherine E., Viana, Lais R., Haidar, Mouna, Watt, Kevin, Qian, Hongwei, Pezzini, Camilla, Zanganeh, Pardis, Turner, Bradley J., Larsson, Anna, Zanchettin, Gianpietro, Pierobon, Elisa S., Moletta, Lucia, Valmasoni, Michele, Ponzoni, Alberto, Attar, Shady, Da Dalt, Gianfranco, Sperti, Cosimo, Kustermann, Monika, Thomson, Rachel E., Larsson, Lars, Loveland, Kate L., Costelli, Paola, Megighian, Aram, Merigliano, Stefano, Penna, Fabio ... Sandri, Marco (2021). Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia. Science Translational Medicine, 13 (605). doi: 10.1126/scitranslmed.aay9592

  • Watt, K., Henstridge, D. C., Ziemann, M., Sim, C. B., Montgomery, M. K., Samocha-Bonet, D., Parker, B. L., Dodd, G. T., Bond, S. T., Salmi, T. M., Lee, R. S., Thomson, R. E., Hagg, A., Davey, J. R., Qian, H., Koopman, R., El-Osta, A., Greenfield, J. R., Watt, M. J., Febbraio, M. A., Drew, B. G., Cox, A. G., Porrello, E. R., Harvey, K. F. and Gregorevic, P. (2021). Yap regulates skeletal muscle fatty acid oxidation and adiposity in metabolic disease. Nature Communications, 12 (1) 2887. doi: 10.1038/s41467-021-23240-7

  • Goodman, Craig A., Davey, Jonathan R., Hagg, Adam, Parker, Benjamin L. and Gregorevic, Paul (2021). Dynamic changes to the skeletal muscle proteome and ubiquitinome induced by the E3 ligase, ASB2β. Molecular and Cellular Proteomics, 20 100050, 100050. doi: 10.1016/j.mcpro.2021.100050

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Supervision

  • Doctor Philosophy

View all Supervision

Publications

Journal Article

  • Sartori, Roberta, Hagg, Adam, Zampieri, Sandra, Armani, Andrea, Winbanks, Catherine E., Viana, Lais R., Haidar, Mouna, Watt, Kevin, Qian, Hongwei, Pezzini, Camilla, Zanganeh, Pardis, Turner, Bradley J., Larsson, Anna, Zanchettin, Gianpietro, Pierobon, Elisa S., Moletta, Lucia, Valmasoni, Michele, Ponzoni, Alberto, Attar, Shady, Da Dalt, Gianfranco, Sperti, Cosimo, Kustermann, Monika, Thomson, Rachel E., Larsson, Lars, Loveland, Kate L., Costelli, Paola, Megighian, Aram, Merigliano, Stefano, Penna, Fabio ... Sandri, Marco (2021). Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia. Science Translational Medicine, 13 (605). doi: 10.1126/scitranslmed.aay9592

  • Watt, K., Henstridge, D. C., Ziemann, M., Sim, C. B., Montgomery, M. K., Samocha-Bonet, D., Parker, B. L., Dodd, G. T., Bond, S. T., Salmi, T. M., Lee, R. S., Thomson, R. E., Hagg, A., Davey, J. R., Qian, H., Koopman, R., El-Osta, A., Greenfield, J. R., Watt, M. J., Febbraio, M. A., Drew, B. G., Cox, A. G., Porrello, E. R., Harvey, K. F. and Gregorevic, P. (2021). Yap regulates skeletal muscle fatty acid oxidation and adiposity in metabolic disease. Nature Communications, 12 (1) 2887. doi: 10.1038/s41467-021-23240-7

  • Goodman, Craig A., Davey, Jonathan R., Hagg, Adam, Parker, Benjamin L. and Gregorevic, Paul (2021). Dynamic changes to the skeletal muscle proteome and ubiquitinome induced by the E3 ligase, ASB2β. Molecular and Cellular Proteomics, 20 100050, 100050. doi: 10.1016/j.mcpro.2021.100050

  • Hagg, Adam, Kharoud, Swati, Goodchild, Georgia, Goodman, Craig A., Chen, Justin L., Thomson, Rachel E., Qian, Hongwei, Gregorevic, Paul, Harrison, Craig A. and Walton, Kelly L. (2020). TMEPAI/PMEPA1 is a positive regulator of skeletal muscle mass. Frontiers in Physiology, 11 560225, 560225. doi: 10.3389/fphys.2020.560225

  • Davey, Jonathan R., Estevez, Emma, Thomson, Rachel E., Whitham, Martin, Watt, Kevin I., Hagg, Adam, Qian, Hongwei, Henstridge, Darren C., Ludlow, Helen, Hedger, Mark P., McGee, Sean L., Coughlan, Melinda T., Febbraio, Mark A. and Gregorevic, Paul (2020). Intravascular Follistatin gene delivery improves glycemic control in a mouse model of type 2 diabetes. The FASEB Journal, 34 (4), 5697-5714. doi: 10.1096/fj.201802059rrr

  • Walton, Kelly L., Chen, Justin L., Arnold, Quinn, Kelly, Emily, La, Mylinh, Lu, Louis, Lovrecz, George, Hagg, Adam, Colgan, Timothy D., Qian, Hongwei, Gregorevic, Paul and Harrison, Craig A. (2019). Activin A–induced cachectic wasting is attenuated by systemic delivery of its cognate propeptide in male mice. Endocrinology, 160 (10), 2417-2426. doi: 10.1210/en.2019-00257

  • Walker, Ryan G., McCoy, Jason C., Czepnik, Magdalena, Mills, Melanie J., Hagg, Adam, Walton, Kelly L., Cotton, Thomas R., Hyvönen, Marko, Lee, Richard T., Gregorevic, Paul, Harrison, Craig A. and Thompson, Thomas B. (2018). Molecular characterization of latent GDF8 reveals mechanisms of activation. Proceedings of the National Academy of Sciences of the United States of America, 115 (5), E866-E875. doi: 10.1073/pnas.1714622115

  • Chen, Justin L., Walton, Kelly L., Hagg, Adam, Colgan, Timothy D., Johnson, Katharine, Qian, Hongwei, Gregorevic, Paul and Harrison, Craig A. (2017). Specific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and disease. Proceedings of the National Academy of Sciences of the United States of America, 114 (26), E5266-E5275. doi: 10.1073/pnas.1620013114

  • Chen, Justin L., Walton, Kelly L., Qian, Hongwei, Colgan, Timothy D., Hagg, Adam, Watt, Matthew J., Harrison, Craig A. and Gregorevic, Paul (2016). Differential effects of IL6 and activin A in the development of cancer-associated cachexia. Cancer Research, 76 (18), 5372-5382. doi: 10.1158/0008-5472.CAN-15-3152

  • Winbanks, Catherine E., Murphy, Kate T., Bernardo, Bianca C., Qian, Hongwei, Liu, Yingying, Sepulveda, Patricio V., Beyer, Claudia, Hagg, Adam, Thomson, Rachel E., Chen, Justin L., Walton, Kelly L., Loveland, Kate L., McMullen, Julie R., Rodgers, Buel D., Harrison, Craig A., Lynch, Gordon S. and Gregorevic, Paul (2016). Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice. Science Translational Medicine, 8 (348). doi: 10.1126/scitranslmed.aac4976

  • Hagg, Adam, Colgan, Timothy D., Thomson, Rachel E., Qian, Hongwei, Lynch, Gordon S. and Gregorevic, Paul (2016). Using AAV vectors expressing the β2-adrenoceptor or associated Gα proteins to modulate skeletal muscle mass and muscle fibre size. Scientific Reports, 6 (1) 23042, 23042. doi: 10.1038/srep23042

  • Sepulveda, Patricio V., Lamon, Severine, Hagg, Adam, Thomson, Rachel E., Winbanks, Catherine E., Qian, Hongwei, Bruce, Clinton R., Russell, Aaron P. and Gregorevic, Paul (2015). Evaluation of follistatin as a therapeutic in models of skeletal muscle atrophy associated with denervation and tenotomy. Scientific Reports, 5 (1) 17535, 17535. doi: 10.1038/srep17535

  • Watt, K. I., Turner, B. J., Hagg, A., Zhang, X., Davey, J. R., Qian, H., Beyer, C., Winbanks, C. E., Harvey, K. F. and Gregorevic, P. (2015). The Hippo pathway effector YAP is a critical regulator of skeletal muscle fibre size. Nature Communications, 6 (1) 6048, 6048. doi: 10.1038/ncomms7048

  • Winbanks, Catherine E., Beyer, Claudia, Hagg, Adam, Qian, Hongwei, Sepulveda, Patricio V. and Gregorevic, Paul (2013). miR-206 represses hypertrophy of myogenic cells but not muscle fibers via inhibition of HDAC4. PLoS One, 8 (9), e73589. doi: 10.1371/journal.pone.0073589

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Associate Advisor