The University of Queensland

Cytokine receptors

Brooks, Andrew J., Dehkhoda, Farhad and Kragelund, Birthe (2018). Cytokine receptors. Endocrinology: principles of endocrinology and hormone action. (pp. 157-185) edited by Antonino Belfiore and Derek LeRoith. Amsterdam, The Netherlands: Springer. doi: 10.1007/978-3-319-44675-2_8

The ATM Ser49Cys Variant Effects ATM Function as a Regulator of Oncogene-Induced Senescence

Atkinson, Caroline, McInerney-Leo, Aideen, Proctor, Martina, Lanagan, Catherine, Stevenson, Alexander, Dehkhoda, Farhad, Caole, Mary, Maas, Ellie, Ainger, Stephen, Pritchard, Antonia, Johansson, Peter, Leo, Paul, Hayward, Nicholas, Sturm, Richard, Duncan, Emma and Gabrielli, Brian (2024). The ATM Ser49Cys Variant Effects ATM Function as a Regulator of Oncogene-Induced Senescence. International Journal of Molecular Sciences, 25 (3), 1664. doi: 10.3390/ijms25031664

Tyrosine kinases compete for growth hormone receptor binding and regulate receptor mobility and degradation

Chhabra, Yash, Seiffert, Pernille, Gormal, Rachel S., Vullings, Manon, Lee, Christine Mei Mei, Wallis, Tristan P., Dehkhoda, Farhad, Indrakumar, Sowmya, Jacobsen, Nina L., Lindorff-Larsen, Kresten, Durisic, Nela, Waters, Michael J., Meunier, Frederic A., Kragelund, Birthe B. and Brooks, Andrew J. (2023). Tyrosine kinases compete for growth hormone receptor binding and regulate receptor mobility and degradation. Cell Reports, 42 (5) 112490, 112490. doi: 10.1016/j.celrep.2023.112490

The SOCS1 KIR and SH2 domain are both required for suppression of cytokine signaling in vivo

Doggett, Karen, Keating, Narelle, Dehkhoda, Farhad, Bidgood, Grace M., Meza Guzman, Lizeth G., Leong, Evelyn, Kueh, Andrew, Nicola, Nicos A., Kershaw, Nadia J., Babon, Jeffrey J., Alexander, Warren S. and Nicholson, Sandra E. (2023). The SOCS1 KIR and SH2 domain are both required for suppression of cytokine signaling in vivo. Cytokine, 165 156167, 1-8. doi: 10.1016/j.cyto.2023.156167

Optimization of phosphotyrosine peptides that target the SH2 domain of SOCS1 and block substrate ubiquitination

Chen, Hao, Wu, Yuntong, Li, Kunlun, Currie, Iain, Keating, Narelle, Dehkhoda, Farhad, Grohmann, Christoph, Babon, Jeffrey J., Nicholson, Sandra E. and Sleebs, Brad E. (2022). Optimization of phosphotyrosine peptides that target the SH2 domain of SOCS1 and block substrate ubiquitination. ACS Chemical Biology, 17 (2), 449-462. doi: 10.1021/acschembio.1c00884

Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands

Linossi, Edmond M., Li, Kunlun, Veggiani, Gianluca, Tan, Cyrus, Dehkhoda, Farhad, Hockings, Colin, Calleja, Dale J., Keating, Narelle, Feltham, Rebecca, Brooks, Andrew J., Li, Shawn S., Sidhu, Sachdev S., Babon, Jeffrey J., Kershaw, Nadia J. and Nicholson, Sandra E. (2021). Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands. Nature Communications, 12 (1) 7032, 7032. doi: 10.1038/s41467-021-26983-5

The growth hormone receptor: mechanism of receptor activation, cell signaling, and physiological aspects

Dehkhoda, Farhad , Lee, Christine M. M. , Medina, Johan and Brooks, Andrew J. (2018). The growth hormone receptor: mechanism of receptor activation, cell signaling, and physiological aspects. Frontiers in Endocrinology, 9 (35) 35, 35. doi: 10.3389/fendo.2018.00035

The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors

Byron, Sara A., Chen, Huaibin, Wortmann, Andreas, Loch, David, Gartside, Michael G., Dehkhoda, Farhad, Blais, Steven P., Neubert, Thomas A., Mohammadi, Moosa and Pollock, Pamela M. (2013). The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors. NeoPlasia, 15 (8), 975-988. doi: 10.1593/neo.121106

Modulation of dopamine's effect at dopamine 2 receptors (D2R) mediated by association with the ghrelin receptor, GHSR

Furness, John, Dehkhoda, Farhad, Whitfield, Emily, Fothergill, Linda, Misgenaw, Desye, Ringuet, Mitchell and Furness, Sebastian (2023). Modulation of dopamine's effect at dopamine 2 receptors (D2R) mediated by association with the ghrelin receptor, GHSR. American Physiology Summit 2023, Long Beach, CA USA, 20-23 April 2023. Rockville, MD USA: American Physiological Society. doi: 10.1152/physiol.2023.38.s1.5731818