The University of Queensland

Reassessing the putative molecular Target(s) of potent antitubercular 2-(Alkylsulfonyl)acetamides

Farr, Dylan C., Haselhorst, Thomas, Tan, Lendl, Furness, Juanelle, Strong, Emily, Grice, I. Darren, West, Nicholas P. and Houston, Todd A. (2024). Reassessing the putative molecular Target(s) of potent antitubercular 2-(Alkylsulfonyl)acetamides. European Journal of Medicinal Chemistry, 264 115983, 1-12. doi: 10.1016/j.ejmech.2023.115983

FDA-approved amoxapine effectively promotes macrophage control of mycobacteria by inducing autophagy

Wang, Jia, Sha, Jian, Strong, Emily, Chopra, Ashok K. and Lee, Sunhee (2022). FDA-approved amoxapine effectively promotes macrophage control of mycobacteria by inducing autophagy. Microbiology Spectrum, 10 (5). doi: 10.1128/spectrum.02509-22

Reversing BCG-mediated autophagy inhibition and mycobacterial survival to improve vaccine efficacy

Gonzalez-Orozco, Maria, Strong, Emily J., Paroha, Ruchi and Lee, Sunhee (2022). Reversing BCG-mediated autophagy inhibition and mycobacterial survival to improve vaccine efficacy. BMC Immunology, 23 (1) 43. doi: 10.1186/s12865-022-00518-z

Mycobacterium tuberculosis PPE51 inhibits autophagy by suppressing toll-like receptor 2-dependent signaling

Strong, Emily J., Wang, Jia, Ng, Tony W., Porcelli, Steven A. and Lee, Sunhee (2022). Mycobacterium tuberculosis PPE51 inhibits autophagy by suppressing toll-like receptor 2-dependent signaling. MBio, 13 (3). doi: 10.1128/mbio.02974-21

Induced synthesis of mycolactone restores the pathogenesis of Mycobacterium ulcerans in vitro and in vivo

Strong, Emily, Hart, Bryan, Wang, Jia, Orozco, Maria Gonzalez and Lee, Sunhee (2022). Induced synthesis of mycolactone restores the pathogenesis of Mycobacterium ulcerans in vitro and in vivo. Frontiers in Immunology, 13 750643. doi: 10.3389/fimmu.2022.750643

Mycobacterium tuberculosis PE_PGRS20 and PE_PGRS47 proteins inhibit autophagy by interaction with Rab1A

Strong, Emily J., Ng, Tony W., Porcelli, Steven A. and Lee, Sunhee (2021). Mycobacterium tuberculosis PE_PGRS20 and PE_PGRS47 proteins inhibit autophagy by interaction with Rab1A. Msphere, 6 (4), 1-17. doi: 10.1128/msphere.00549-21

Targeting autophagy as a strategy for developing new vaccines and host-directed therapeutics against mycobacteria

Strong, Emily J. and Lee, Sunhee (2021). Targeting autophagy as a strategy for developing new vaccines and host-directed therapeutics against mycobacteria. Frontiers in Microbiology, 11 614313. doi: 10.3389/fmicb.2020.614313

Identification of autophagy-inhibiting factors of mycobacterium tuberculosis by high-throughput loss-of-function screening

Strong, Emily J., Jurcic Smith, Kristen L., Saini, Neeraj K., Ng, Tony W., Porcelli, Steven A. and Lee, Sunhee (2020). Identification of autophagy-inhibiting factors of mycobacterium tuberculosis by high-throughput loss-of-function screening. Infection and Immunity, 88 (12) e00269-20. doi: 10.1128/IAI.00269-20

Homologous alignment cloning: a rapid, flexible and highly efficient general molecular cloning method

Tan, Lendl, Strong, Emily J., Woods, Kyra and West, Nicholas P. (2018). Homologous alignment cloning: a rapid, flexible and highly efficient general molecular cloning method. PeerJ, 6 (6) e5146, e5146. doi: 10.7717/peerj.5146

Use of soluble extracellular regions of MmpL (SERoM) as vaccines for tuberculosis

Strong, Emily J. and West, Nicholas P. (2018). Use of soluble extracellular regions of MmpL (SERoM) as vaccines for tuberculosis. Scientific Reports, 8 (1) 5604, 5604. doi: 10.1038/s41598-018-23893-3

Burkholderia pseudomallei capsule exacerbates respiratory melioidosis but does not afford protection against antimicrobial signaling or bacterial killing in human olfactory ensheathing cells

Dando, Samantha J., Ipe, Deepak S., Batzloff, Michael, Sullivan, Matthew J., Crossman, David K., Crowley, Michael, Strong, Emily, Kyan, Stephanie, Leclercq, Sophie Y., Ekberg, Jenny A. K., St John, James, Beacham, Ifor R. and Ulett, Glen C. (2016). Burkholderia pseudomallei capsule exacerbates respiratory melioidosis but does not afford protection against antimicrobial signaling or bacterial killing in human olfactory ensheathing cells. Infection and Immunity, 84 (7), 1941-1956. doi: 10.1128/IAI.01546-15

Macrophage plasticity and activation states drive differential expression of murine macrophage galactose-type lectin (MGL) orthologs

Paez, Reina N., Browning, Sarah, Files, Megan A., Varghese, Alyssa A., Huante, Matthew B., Strong, Emily, Lee, Sunhee, Endsley, Mark A. and Endsley, Janice J. (2023). Macrophage plasticity and activation states drive differential expression of murine macrophage galactose-type lectin (MGL) orthologs. Annual Meeting of the American Association of Immunologists (AAI), Washington, DC United States, 11-15 May 2023. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.210.Supp.160.32

A Functional Genomics Approach to Vaccine Development Against Mycobacterium tuberculosis and the Role MmpL13 Plays in Tuberculosis Infection

Strong, Emily (2017). A Functional Genomics Approach to Vaccine Development Against Mycobacterium tuberculosis and the Role MmpL13 Plays in Tuberculosis Infection. PhD Thesis, School of Chemistry & Molecular Biosciences, The University of Queensland. doi: 10.14264/uql.2017.1037