The University of Queensland

Tandem affinity purification to identify cytosolic and nuclear Gβγ-interacting proteins

Campden, Rhiannon, Petrin, Darlaine, Robitaille, Melanie, Audet, Nicolas, Gora, Sarah, Angers, Stephane and Hebert, Terence E. (2015). Tandem affinity purification to identify cytosolic and nuclear Gβγ-interacting proteins. Nuclear G-protein coupled receptors. (pp. 161-184) edited by Bruce G. Allen and Terence E. Hébert. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-1755-6_14

Real-time BRET assays to measure G protein/effector interactions

Petrin, Darlaine, Robitaille, Melanie and Hebert, Terence E. (2011). Real-time BRET assays to measure G protein/effector interactions. Signal Transduction Protocols . (pp. 245-261) edited by Louis M. Luttrell and Stephen S. G. Ferguson. Totowa, NJ, United States: Humana Press. doi: 10.1007/978-1-61779-160-4_13

Novel tools for use in Bioluminescence Resonance Energy Transfer (BRET) assays

Robitaille, Melanie, Heroux, Isabelle, Baragli, Alessandra and Hebert, Terence E. (2009). Novel tools for use in Bioluminescence Resonance Energy Transfer (BRET) assays. Bioluminescence: Methods and Protocols. (pp. 215-234) edited by Preston B. Rich and Christelle Douillet. Totowa, NJ, United States: Humana Press. doi: 10.1007/978-1-60327-321-3_18

Cellular geometry and epithelial-mesenchymal plasticity intersect with PIEZO1 in breast cancer cells

So, Choon Leng, Robitaille, Mélanie, Sadras, Francisco, McCullough, Michael H., Milevskiy, Michael J. G., Goodhill, Geoffrey J., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2024). Cellular geometry and epithelial-mesenchymal plasticity intersect with PIEZO1 in breast cancer cells. Communications Biology, 7 (1) 467. doi: 10.1038/s42003-024-06163-z

The intersection between cysteine proteases, Ca2+ signalling and cancer cell apoptosis

Hua, Trinh, Robitaille, Mélanie, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2023). The intersection between cysteine proteases, Ca2+ signalling and cancer cell apoptosis. Biochimica et Biophysica Acta - Molecular Cell Research, 1870 (7) 119532, 1-13. doi: 10.1016/j.bbamcr.2023.119532

TRPV4 and the paradox of faster cellular migration rates in more viscous extracellular fluids

So, Choon Leng, Robitaille, Mélanie and Monteith, Gregory R. (2023). TRPV4 and the paradox of faster cellular migration rates in more viscous extracellular fluids. Cell Calcium, 109 102685, 1-3. doi: 10.1016/j.ceca.2022.102685

AKT regulation of ORAI1-mediated calcium influx in breast cancer cells

Bong, Alice Hui Li, Hua, Trinh, So, Choon Leng, Peters, Amelia A., Robitaille, Mélanie, Tan, Yin Yi, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2022). AKT regulation of ORAI1-mediated calcium influx in breast cancer cells. Cancers, 14 (19) 4794, 1-14. doi: 10.3390/cancers14194794

Increased matrix stiffness suppresses ATP-induced sustained Ca2+ influx in MDA-MB-231 breast cancer cells

So, Choon Leng, Meinert, Christoph, Xia, Qing, Robitaille, Mélanie, Roberts-Thomson, Sarah J and Monteith, Gregory R (2022). Increased matrix stiffness suppresses ATP-induced sustained Ca2+ influx in MDA-MB-231 breast cancer cells. Cell Calcium, 104 102569, 1-10. doi: 10.1016/j.ceca.2022.102569

ORAI1-regulated gene expression in breast cancer cells: Roles for STIM1 binding, calcium influx and transcription factor translocation

Robitaille, Mélanie, Chan, Shao Ming, Peters, Amelia A., Dai, Limin, So, Choon Leng, Bong, Alice H. L., Sadras, Francisco, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2022). ORAI1-regulated gene expression in breast cancer cells: Roles for STIM1 binding, calcium influx and transcription factor translocation. International Journal of Molecular Sciences, 23 (11) 5867, 1-14. doi: 10.3390/ijms23115867

Uncoiling the link between STIM1 and metastatic pathways in estrogen receptor negative breast cancer cells

Monteith, Prof. Gregory R, Robitaille, Mélanie and Roberts-Thomson, Sarah J. (2022). Uncoiling the link between STIM1 and metastatic pathways in estrogen receptor negative breast cancer cells. Cell Calcium, 103 102563, 102563. doi: 10.1016/j.ceca.2022.102563

ORAI1 regulates sustained cytosolic free calcium fluctuations during breast cancer cell apoptosis and apoptotic resistance via a STIM1 independent pathway

Bassett, John J., Robitaille, Mélanie, Peters, Amelia A., Bong, Alice H. L., Taing, Meng‐Wong, Wood, Ian A., Sadras, Francisco, Roberts‐Thomson, Sarah J. and Monteith, Gregory R. (2022). ORAI1 regulates sustained cytosolic free calcium fluctuations during breast cancer cell apoptosis and apoptotic resistance via a STIM1 independent pathway. The FASEB Journal, 36 (1) e22108, e22108. doi: 10.1096/fj.202002031rr

Altered calcium influx pathways in cancer-associated fibroblasts

Sadras, Francisco, Stewart, Teneale A., Robitaille, Mélanie, Peters, Amelia A., Croft, Priyakshi Kalita-de, Soon, Patsy S., Saunus, Jodi M., Lakhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2021). Altered calcium influx pathways in cancer-associated fibroblasts. Biomedicines, 9 (6) 680, 1-13. doi: 10.3390/biomedicines9060680

Activation of the ion channel TRPV4 induces epithelial to mesenchymal transition in breast cancer cells

Azimi, Iman, Robitaille, Mélanie, Armitage, Kaela, So, Choon Leng, Milevskiy, Michael J. G., Northwood, Korinne, Lim, Huai Fang, Thompson, Erik W., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2020). Activation of the ion channel TRPV4 induces epithelial to mesenchymal transition in breast cancer cells. International Journal of Molecular Sciences, 21 (24) 9417, 1-14. doi: 10.3390/ijms21249417

NCS-1 expression is higher in basal breast cancers and regulates calcium influx and cytotoxic responses to doxorubicin

Bong, Alice H. L., Robitaille, Mélanie, Milevskiy, Michael J. G., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2019). NCS-1 expression is higher in basal breast cancers and regulates calcium influx and cytotoxic responses to doxorubicin. Molecular Oncology, 14 (1) 1878-0261.12589, 87-104. doi: 10.1002/1878-0261.12589

ARGLU1 is a transcriptional coactivator and splicing regulator important for stress hormone signaling and development

Magomedova, Lilia, Tiefenbach, Jens, Zilberman, Emma, Le Billan, Florian, Voisin, Veronique, Saikali, Michael, Boivin, Vincent, Robitaille, Melanie, Gueroussov, Serge, Irimia, Manuel, Ray, Debashish, Patel, Rucha, Xu, ChangJiang, Jeyasuria, Pancharatnam, Bader, Gary D, Hughes, Timothy R, Morris, Quaid D, Scott, Michelle S, Krause, Henry, Angers, Stephane, Blencowe, Benjamin J and Cummins, Carolyn L (2019). ARGLU1 is a transcriptional coactivator and splicing regulator important for stress hormone signaling and development. Nucleic Acids Research, 47 (6), 2856-2870. doi: 10.1093/nar/gkz010

ORAI1 and ORAI3 in breast cancer molecular subtypes and the identification of ORAI3 as a hypoxia sensitive gene and a regulator of hypoxia responses

Azimi, Iman, Milevskiy, Michael J. G., Chalmers, Silke B., Yapa, Kunsala T. D. S., Robitaille, Mélanie, Henry, Christopher, Baillie, Gregory J., Thompson, Erik W., Roberts-Thomson, Sarah J and Monteith, Gregory R (2019). ORAI1 and ORAI3 in breast cancer molecular subtypes and the identification of ORAI3 as a hypoxia sensitive gene and a regulator of hypoxia responses. Cancers, 11 (2) 208. doi: 10.3390/cancers11020208

A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties

Pavlovic, Zvezdan, Adams, Jarrett J., Blazer, Levi L., Gakhal, Amandeep K., Jarvik, Nick, Steinhart, Zachary, Robitaille, Melanie, Mascall, Keith, Pan, James, Angers, Stephane, Moffat, Jason and Sidhu, Sachdev S. (2018). A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties. mAbs, 10 (8), 1157-1167. doi: 10.1080/19420862.2018.1515565

Assessment of cytosolic free calcium changes during ceramide-induced cell death in MDA-MB-231 breast cancer cells expressing the calcium sensor GCaMP6m

Bassett, John J., Bong, Alice H.L., Janke, Ellen K., Robitaille, Mélanie, Roberts-Thomson, Sarah J., Peters, Amelia A. and Monteith, Gregory R. (2018). Assessment of cytosolic free calcium changes during ceramide-induced cell death in MDA-MB-231 breast cancer cells expressing the calcium sensor GCaMP6m. Cell Calcium, 72, 39-50. doi: 10.1016/j.ceca.2018.02.003

Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors

Steinhart, Zachary, Pavlovic, Zvezdan, Chandrashekhar, Megha, Hart, Traver, Wang, Xiaowei, Zhang, Xiaoyu, Robitaille, Melanie, Browne, Kevin R., Jaksani, Sridevi, Overmeer, Rene, Boj, Sylvia F., Adams, Jarrett, Pan, James, Clevers, Hans, Sidhu, Sachdev, Moffat, Jason and Angers, Stephane (2017). Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors. Nature Medicine, 23 (1), 60-68. doi: 10.1038/nm.4219

YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells

Dey, A., Robitaille, M., Remke, M., Maier, C., Malhotra, A., Gregorieff, A., Wrana, J. L., Taylor, M. D., Angers, S. and Kenney, A. M. (2016). YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells. Oncogene, 35 (32), 4256-4268. doi: 10.1038/onc.2015.491

SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the G alpha i-LGN-NuMA Ternary Complex

Chiu, Catherine W. N., Monat, Carine, Robitaille, Melanie, Lacomme, Marine, Daulat, Avais M., Macleod, Graham, McNeill, Helen, Cayouette, Michel and Angers, Stephane (2016). SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the G alpha i-LGN-NuMA Ternary Complex. Developmental Cell, 36 (1), 50-62. doi: 10.1016/j.devcel.2015.12.016

Gβ4γ1 as a modulator of M3 muscarinic receptor signalling and novel roles of Gβ1 subunits in the modulation of cellular signalling

Khan, Shahriar M., Min, Adam, Gora, Sarah, Houranieh, Geeda M., Campden, Rhiannon, Robitaille, Melanie, Trieu, Phan, Petrin, Darlaine, Jacobi, Ashley M., Behlke, Mark A., Angers, Stephane and Hebert, Terence E. (2015). Gβ4γ1 as a modulator of M3 muscarinic receptor signalling and novel roles of Gβ1 subunits in the modulation of cellular signalling. Cellular Signalling, 27 (8), 1597-1608. doi: 10.1016/j.cellsig.2015.04.007

BioID-based identification of SKP Cullin F-box (SCF)(beta-TrCP1/2) E3 ligase substrates

Coyaud, Etienne, Mis, Monika, Laurent, Estelle M. N., Dunham, Wade H., Couzens, Amber L., Robitaille, Melanie, Gingras, Anne-Claude, Angers, Stephane and Raught, Brian (2015). BioID-based identification of SKP Cullin F-box (SCF)(beta-TrCP1/2) E3 ligase substrates. Molecular & Cellular Proteomics, 14 (7), 1781-1795. doi: 10.1074/mcp.M114.045658

The identification of novel protein-protein interactions in liver that affect glucagon receptor activity

Han, Junfeng, Zhang, Ming, Froese, Sean, Dai, Feihan F., Robitaille, Melanie, Bhattacharjee, Alpana, Huang, Xinyi, Jia, Weiping, Angers, Stephane, Wheeler, Michael B. and Wei, Li (2015). The identification of novel protein-protein interactions in liver that affect glucagon receptor activity. Plos One, 10 (6), e0129226. doi: 10.1371/journal.pone.0129226

Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic beta cells

Zhang, Ming, Robitaille, Melanie, Showalter, Aaron D., Huang, Xinyi, Liu, Ying, Bhattacharjee, Alpana, Willard, Francis S., Han, Junfeng, Froese, Sean, Wei, Li, Gaisano, Herbert Y., Angers, Stephane, Sloop, Kyle W., Dai, Feihan F. and Wheeler, Michael B. (2014). Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic beta cells. Molecular and Cellular Proteomics, 13 (11), 3049-3062. doi: 10.1074/mcp.M114.040196

Ubiquitylation and activation of a Rab GTPase is promoted by a beta(2)AR-HACE1 complex

Lachance, Veronik, Degrandmaison, Jade, Marois, Sebastien, Robitaille, Melanie, Genier, Samuel, Nadeau, Stephanie, Angers, Stephane and Parent, Jean-Luc (2014). Ubiquitylation and activation of a Rab GTPase is promoted by a beta(2)AR-HACE1 complex. Journal of Cell Science, 127 (1), 111-123. doi: 10.1242/jcs.132944

Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability

Roy, Sebastien J., Glazkova, Irina, Frechette, Louis, Iorio-Morin, Christian, Binda, Chantal, Petrin, Darlaine, Phan Trieu,, Robitaille, Melanie, Angers, Stephane, Hebert, Terence E. and Parent, Jean-Luc (2013). Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability. Molecular Endocrinology, 27 (8), 1245-1266. doi: 10.1210/me.2013-1091

A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression

Anastas, J. N., Biechele, T. L., Robitaille, M., Muster, J., Allison, K. H., Angers, S. and Moon, R. T. (2012). A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression. Oncogene, 31 (32), 3696-3708. doi: 10.1038/onc.2011.528

Gβγ is a negative regulator of AP-1 mediated transcription

Robitaille, Melanie, Gora, Sarah, Wang, Ying, Goupil, Eugenie, Petrin, Darlaine, Del Duca, Danny, Villeneuve, Louis R., Allen, Bruce G., Laporte, Stephane A., Bernard, Daniel J. and Hebert, Terence E. (2010). Gβγ is a negative regulator of AP-1 mediated transcription. Cellular Signalling, 22 (8), 1254-1266. doi: 10.1016/j.cellsig.2010.04.005

The Role of G beta gamma subunits in the organization, assembly, and function of GPCR signaling complexes

Dupre, Denis J., Robitaille, Melanie, Rebois, R. Victor and Hebert, Terence E. (2009). The Role of G beta gamma subunits in the organization, assembly, and function of GPCR signaling complexes. Annual Review of Pharmacology and Toxicology, 49 (1), 31-56. doi: 10.1146/annurev-pharmtox-061008-103038

Fonction des chaperonnes moléculaires dans l’assemblage des protéines G hétérotrimériques

Robitaille, Mélanie, Dupré, Denis J. and Hébert, Terence E. (2009). Fonction des chaperonnes moléculaires dans l’assemblage des protéines G hétérotrimériques. Médecine/Sciences, 25 (10), 821-825. doi: 10.1051/medsci/20092510821

The role of molecular chaperones in the assembly of heterotrimeric G proteins

Robitaille, Melanie, Dupre, Denis J. and Hebert, Terence E. (2009). The role of molecular chaperones in the assembly of heterotrimeric G proteins. M S-Medecine Sciences, 25 (10), 821-825. doi: 10.1051/medsci/20092510821

Rab1 GTPase and dimerization in the cell surface expression of angiotensin II type 2 receptor

Zhang, Xiaoping, Wang, Guansong, Dupre, Denis J., Feng, Yumei, Robitaille, Melanie, Lazartigues, Eric, Feng, Ying-Hong, Hebert, Terence E. and Wu, Guangyu (2009). Rab1 GTPase and dimerization in the cell surface expression of angiotensin II type 2 receptor. Journal of Pharmacology and Experimental Therapeutics, 330 (1), 109-117. doi: 10.1124/jpet.109.153460

A single conserved leucine residue on the first intracellular loop regulates ER export of G protein-coupled receptors

Duvernay, Matthew T., Dong, Chunmin, Zhang, Xiaoping, Robitaille, Melanie, Hebert, Terence E. and Wu, Guangyu (2009). A single conserved leucine residue on the first intracellular loop regulates ER export of G protein-coupled receptors. Traffic, 10 (5), 552-566. doi: 10.1111/j.1600-0854.2009.00890.x

Intracellular trafficking and assembly of specific Kir3 channel/G protein complexes

Robitaille, Melanie, Ramakrishnan, Nitya, Baragli, Alessandra and Hebert, Terence E. (2009). Intracellular trafficking and assembly of specific Kir3 channel/G protein complexes. Cellular Signalling, 21 (4), 488-501. doi: 10.1016/j.cellsig.2008.11.011

Combining protein complementation assays with resonance energy transfer to detect multipartner protein complexes in living cells

Rebois, R. Victor, Robitaille, Melanie, Petrin, Darlaine, Zylbergold, Peter, Trieu, Phan and Hebert, Terence E. (2008). Combining protein complementation assays with resonance energy transfer to detect multipartner protein complexes in living cells. Methods, 45 (3), 214-218. doi: 10.1016/j.ymeth.2008.06.006

Dopamine receptor-interacting protein 78 acts as a molecular chaperone for G gamma subunits before assembly with G beta

Dupre, Denis J., Robitaille, Melanie, Richer, Maxime, Ethier, Nathalie, Mamarbachi, Aida M. and Hebert, Terence E. (2007). Dopamine receptor-interacting protein 78 acts as a molecular chaperone for G gamma subunits before assembly with G beta. Journal of Biological Chemistry, 282 (18), 13703-13715. doi: 10.1074/jbc.M608846200

Seven transmembrane receptor core signaling complexes are assembled prior to plasma membrane trafficking

Dupre, Denis J., Robitaille, Melanie, Ethier, Nathalie, Villeneuve, Louis R., Mamarbachi, Aida M. and Hebert, Terence E. (2006). Seven transmembrane receptor core signaling complexes are assembled prior to plasma membrane trafficking. Journal of Biological Chemistry, 281 (45), 34561-34573. doi: 10.1074/jbc.M605012200

Heterotrimeric G proteins form stable complexes with adenylyl cyclase and Kir3.1 channels in living cells

Rebois, R. Victor, Robitaille, Melanie, Gales, Celine, Dupre, Denis J., Baragli, Alessandra, Trieu, Phan, Ethier, Nathalie, Bouvier, Michel and Hebert, Terence E. (2006). Heterotrimeric G proteins form stable complexes with adenylyl cyclase and Kir3.1 channels in living cells. Journal of Cell Science, 119 (13), 2807-2818. doi: 10.1242/jcs.03021

Abstract 3629: Calcium signalling and the breast cancer microenvironment

Bong, Alice H., Gieniec, Krystyna A., Sadras, Francisco, Robitaille, Mélanie, Roberts-Thomson, Sarah J., Davis, Felicity M. and Monteith, Gregory R. (2023). Abstract 3629: Calcium signalling and the breast cancer microenvironment. 114th Annual Meeting of the American Association for Cancer Research (AACR), Orlando, FL United States, 14-19 April 2023. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2023-3629

Remodelling of calcium influx pathways in breast cancer associated fibroblasts

Sadras, Francisco, Stewart, Teneale A., Robitaille, Melanie, Peters, Amelia A., Kalita-de Croft, Priyakshi, Soon, Patsy, Saunus, Jodi M., Lakhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2020). Remodelling of calcium influx pathways in breast cancer associated fibroblasts. 2019 San Antonio Breast Cancer Symposium, San Antonio, TX United States, 10-14 December 2019. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.sabcs19-p6-06-15

A recently identified ion channel in breast cancer

Bong, Alice H. L., Robitaille, Mélanie, Milevskiy, Michael J. G., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2019). A recently identified ion channel in breast cancer. AuPS/ASB Scientific meeting, Canberra, Australia, 1-4 December 2019.

Assessment of Ca2+ channels and pumps in brain-seeking breast cancer cell lines

Lim, Darren Z. R. , Chalmers, Silke B. , Robitaille, Melanie , Saunus, Jodi M. , Lakhani, Sunil R. , Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2019). Assessment of Ca2+ channels and pumps in brain-seeking breast cancer cell lines. ASCEPT-PAGANZ Joint Scientific Meeting, Queenstown, New Zealand, 25-29 November 2019. Hamilton Central, QLD, Australia: ASCEPT.

Remodeling of calcium influx pathways in models of cancer associated fibroblasts in breast cancer

Monteith, Greg, Sadras, Francisco, Stewart, Teneale, Robitaille, Melanie, Kalita-de Croft, Priyakshi, Soon, Patsy, Saunus, Jodi, Lakhani, Sunil and Roberts-Thomson, Sarah (2019). Remodeling of calcium influx pathways in models of cancer associated fibroblasts in breast cancer. AACR Annual Meeting on Bioinformatics, Convergence Science, and Systems Biology, Atlanta, GA United States, 29 March - 3 April 2019. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS18-99

Cancer associated fibroblasts undergo a calcium channel switch

Sadras, Francisco, Stewart, Teneale A., Robitaille, Melanie, Kalita-de Croft, Priyakshi, Patsy, Soon, Saunus, Jodi M., Makhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2018). Cancer associated fibroblasts undergo a calcium channel switch. Australasian Society for Clinical and Experimental Pharmacologists and Toxicologists, Adelaide, SA, Australia, 27 - 30 November 2018.

Expression of calcium pumps, channels and channel regulators in a model of therapy resistance in melanoma

Chua, Chia C., Hammerlinde, Heinz, Robitaille, Melanie, Roberts-Thomson, Sarah J., Schauder, Helmut and Monteith, Gregory R. (2018). Expression of calcium pumps, channels and channel regulators in a model of therapy resistance in melanoma. Australasian Society for Clinical and Experimental Pharmacologists and Toxicologists, Adelaide, SA Australia, 27 - 30 November 2018.

Sonic Hedgehog induces YB-1 in a yap-dependent manner to regulate Igf2 expression and proliferation in cerebellar granule neuron progenitors and medulloblastoma cells

Dey, A., Robitaille, M., Remke, M., Maier, C., Malhotra, A., Gregorieff, A., Wrana, J., Taylor, M., Angers, S. and Kenney, A. (2015). Sonic Hedgehog induces YB-1 in a yap-dependent manner to regulate Igf2 expression and proliferation in cerebellar granule neuron progenitors and medulloblastoma cells. 3rd Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, San Diego, CA United States, 7-8 May 2015. Cary, NC United States: Oxford University Press. doi: 10.1093/neuonc/nov061.78

Transcriptional regulation at IGF2 promoters and mechanistic insights on induction of IGF2 downstream of yap in SHH medulloblastomas

Dev, Abhinav, Robitaille, Melanie, Remke, Marc, Faury, Damien, Maier, Caroline, Malhotra, Anshu, Jabado, Nada, Taylor, Michael, Angers, Stephane and Kenney, Anna (2013). Transcriptional regulation at IGF2 promoters and mechanistic insights on induction of IGF2 downstream of yap in SHH medulloblastomas. 4th Quadrennial Meeting of the World-Federation-of-Neuro-Oncology (WFNO) held in conjunction with the 18th Annual Meeting of the Society-for-Neuro-Oncology (SNO), San Francisco, CA United States, 21-24 November 2013. Cary, NC United States: Oxford University Press.

Characterization of a novel protein interactor of galphai suggests its involvement in mitotic spindle orientation

Chiu, Catherine, Robitaille, Melanie, Daulat, Avais, Zhao, Peishen, Chidiac, Peter, Obiero, Josiah and Angers, Stephane (2013). Characterization of a novel protein interactor of galphai suggests its involvement in mitotic spindle orientation. GPCR 2012, -, 2012. London, United Kingdom: Taylor & Francis.

Unraveling 7tm receptor protein interaction landscape by proximity-depdendent biotin-labeling

Robitaille, Melanie and Angers, Stephane (2013). Unraveling 7tm receptor protein interaction landscape by proximity-depdendent biotin-labeling. GPCR 2012, -, 2012. London, United Kingdom: Taylor & Francis.

An unbiased proteomic screen for nuclear G beta gamma subunit interactors

Campden, R., Petrin, D., Robitaille, M., Angers, S. and Hebert, T. E. (2013). An unbiased proteomic screen for nuclear G beta gamma subunit interactors. ASCB Annual Meeting 2013, New Orleans, LA United States, 14-18 December 2013. Bethesda, MD United States: American Society for Cell Biology.

Sapcd2, a novel G alpha i-interacting protein regulating mitotic spindle orientation

Monat, C., Chiu, C., Robitaille, M., Daulat, A., Zhao, P., Chidiac, P., Cayouette, M. and Angers, S. (2013). Sapcd2, a novel G alpha i-interacting protein regulating mitotic spindle orientation. ASCB Annual Meeting 2013, New Orleans, LA United States, 14-18 December 2013. Bethesda, MD United States: American Society for Cell Biology.