Dr Natacha Omer is a paediatic oncologist at the Queensland Children's Hospital in Brisbane. She is specialised in solid tumours, with a spacial interest in paediatric and adolescent sarcomas, cancer immunotherapy and molecular oncology. She is undertaking a PhD in immunology studying natural killer (NK) cell immunotherapy in paediatric sarcomas at the Frazer Institute, University of Queensland, in Dr Fernando Guimaraes lab.
Ramamurthy, Ashika, Connolly, Elizabeth A, Mar, Jasmine, Lewin, Jeremy, Bhadri, Vivek A, Phillips, Marianne B, Winstanley, Mark, Orme, Lisa M, Grimison, Peter, Connor, Joanna, Lazarakis, Smaro, Hong, Angela M, Omer, Natacha and Cayrol, Julie (2024). High-dose chemotherapy for Ewing sarcoma and Rhabdomyosarcoma: A systematic review by the Australia and New Zealand sarcoma association clinical practice guidelines working party. Cancer Treatment Reviews, 124 102694, 102694. doi: 10.1016/j.ctrv.2024.102694
Journal Article: A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer
Mayoh, Chelsea, Gifford, Andrew J., Terry, Rachael, Lau, Loretta M S, Wong, Marie, Rao, Padmashree, Shai-Hee, Tyler, Saletta, Federica, Khuong-Quang, Dong-Anh, Qin, Vicky, Mateos, Marion K., Meyran, Deborah, Miller, Katherine E., Yuksel, Aysen, Mould, Emily V A, Bowen-James, Rachel, Govender, Dinisha, Senapati, Akanksha, Zhukova, Nataliya, Omer, Natacha, Dholaria, Hetal, Alvaro, Frank, Tapp, Heather, Diamond, Yonatan, Pozza, Luciano Dalla, Moore, Andrew S., Nicholls, Wayne, Gottardo, Nicholas G., McCowage, Geoffrey ... Ekert, Paul G. (2023). A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer. Genome Medicine, 15 (1) 20, 20. doi: 10.1186/s13073-023-01170-x
Journal Article: Enhancing the potential of immunotherapy in paediatric sarcomas: breaking the immunosuppressive barrier with receptor tyrosine kinase inhibitors
Fleuren, Emmy D. G., Terry, Rachael L., Meyran, Deborah, Omer, Natacha, Trapani, Joseph A., Haber, Michelle, Neeson, Paul J. and Ekert, Paul G. (2021). Enhancing the potential of immunotherapy in paediatric sarcomas: breaking the immunosuppressive barrier with receptor tyrosine kinase inhibitors. Biomedicines, 9 (12) 1798, 1798. doi: 10.3390/biomedicines9121798
Training Natural Killer Cells for Immunotherapy for Children, Adolescent, and Adults with Sarcoma
(2023–2030) Cooper Rice-Brading Foundation Ltd/Tie Dye Project
Ramamurthy, Ashika, Connolly, Elizabeth A, Mar, Jasmine, Lewin, Jeremy, Bhadri, Vivek A, Phillips, Marianne B, Winstanley, Mark, Orme, Lisa M, Grimison, Peter, Connor, Joanna, Lazarakis, Smaro, Hong, Angela M, Omer, Natacha and Cayrol, Julie (2024). High-dose chemotherapy for Ewing sarcoma and Rhabdomyosarcoma: A systematic review by the Australia and New Zealand sarcoma association clinical practice guidelines working party. Cancer Treatment Reviews, 124 102694, 102694. doi: 10.1016/j.ctrv.2024.102694
A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer
Mayoh, Chelsea, Gifford, Andrew J., Terry, Rachael, Lau, Loretta M S, Wong, Marie, Rao, Padmashree, Shai-Hee, Tyler, Saletta, Federica, Khuong-Quang, Dong-Anh, Qin, Vicky, Mateos, Marion K., Meyran, Deborah, Miller, Katherine E., Yuksel, Aysen, Mould, Emily V A, Bowen-James, Rachel, Govender, Dinisha, Senapati, Akanksha, Zhukova, Nataliya, Omer, Natacha, Dholaria, Hetal, Alvaro, Frank, Tapp, Heather, Diamond, Yonatan, Pozza, Luciano Dalla, Moore, Andrew S., Nicholls, Wayne, Gottardo, Nicholas G., McCowage, Geoffrey ... Ekert, Paul G. (2023). A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer. Genome Medicine, 15 (1) 20, 20. doi: 10.1186/s13073-023-01170-x
Fleuren, Emmy D. G., Terry, Rachael L., Meyran, Deborah, Omer, Natacha, Trapani, Joseph A., Haber, Michelle, Neeson, Paul J. and Ekert, Paul G. (2021). Enhancing the potential of immunotherapy in paediatric sarcomas: breaking the immunosuppressive barrier with receptor tyrosine kinase inhibitors. Biomedicines, 9 (12) 1798, 1798. doi: 10.3390/biomedicines9121798
Enhancing natural killer cell targeting of pediatric sarcoma
Omer, Natacha, Nicholls, Wayne, Ruegg, Bronte, Souza-Fonseca-Guimaraes, Fernando and Rossi, Gustavo Rodrigues (2021). Enhancing natural killer cell targeting of pediatric sarcoma. Frontiers in Immunology, 12 791206, 791206. doi: 10.3389/fimmu.2021.791206
Terry, Rachael L., Meyran, Deborah, Fleuren, Emmy D. G., Mayoh, Chelsea, Zhu, Joe, Omer, Natacha, Ziegler, David S., Haber, Michelle, Darcy, Phillip K., Trapani, Joseph A., Neeson, Paul J. and Ekert, Paul G. (2021). Chimeric antigen receptor T cell therapy and the immunosuppressive tumor microenvironment in pediatric sarcoma. Cancers, 13 (18) 4704. doi: 10.3390/cancers13184704
Phase-II trials in osteosarcoma recurrences: a systematic review of past experience
Omer, Natacha, Le Deley, Marie-Cecile, Piperno-Neumann, Sophie, Marec-Berard, Perrine, Italiano, Antoine, Corradini, Nadege, Bellera, Carine, Brugieres, Laurence and Gaspar, Nathalie (2017). Phase-II trials in osteosarcoma recurrences: a systematic review of past experience. European Journal of Cancer, 75, 98-108. doi: 10.1016/j.ejca.2017.01.005
Precision medicine search for paediatric oncology
Koopman, Bevan, Wright, Tracey, Omer, Natacha, McCabe, Veronica and Zuccon, Guido (2021). Precision medicine search for paediatric oncology. 44th International ACM SIGIR Conference on Research and Development in Information Retrieval, Virtual, 11 - 15 July, 2021. New York, NY, United States: Association for Computing Machinery. doi: 10.1145/3404835.3462792
Khuong-Quang, Dong-Anh, Nagabushan, Sumanth, Manoharan, Neevika, Arndt, Greg, Barahona, Paulette, Cowley, Mark J, Ekert, Paul G, Failes, Tim, Bolanos, Noemi Fuentes, Gauthier, Maely, Gifford, Andrew J, Haber, Michelle, Kumar, Amit, Lock, Richard B, Marshall, Glenn M, Mayoh, Chelsea, Mould, Emily, Norris, Murray D, Gopalakrishnan, Anjana, Omer, Natacha, Trebilcock, Peter, Trahair, Toby N, Tsoli, Maria, Tucker, Katherine, Wong, Marie, Tyrrell, Vanessa, Lau, Loretta and S, Ziegler, David (2020). Precision medicine for paediatric high-grade diffuse midline gliomas - results from the zero childhood cancer comprehensive precision medicine program. 19th International Symposium on Pediatric Neuro-Oncology (ISPNO 2020), Karuizawa, Japan, 13-16 December 2020. Cary, NC, United States: Oxford University Press . doi: 10.1093/neuonc/noaa222.117
Training Natural Killer Cells for Immunotherapy for Children, Adolescent, and Adults with Sarcoma
(2023–2030) Cooper Rice-Brading Foundation Ltd/Tie Dye Project