The University of Queensland

Epithelial Mechanosensing at Cell-Cell Contacts and Tight Junctions

Brooks, John W., Parton, Robert G., Yap, Alpha S. and Duszyc, Kinga (2022). Epithelial Mechanosensing at Cell-Cell Contacts and Tight Junctions. Tight Junctions. (pp. 27-50) Cham: Springer International Publishing. doi: 10.1007/978-3-030-97204-2_3

Apical extrusion prevents apoptosis from activating an acute inflammatory program in epithelia

Duszyc, Kinga, von Pein, Jessica B., Ramnath, Divya, Currin-Ross, Denni, Verma, Suzie, Lim, Fayth, Sweet, Matthew J., Schroder, Kate and Yap, Alpha S. (2023). Apical extrusion prevents apoptosis from activating an acute inflammatory program in epithelia. Developmental Cell, 58 (21), 2235-2248.e6. doi: 10.1016/j.devcel.2023.08.009

Dynamically regulated focal adhesions coordinate endothelial cell remodelling in developing vasculature

Chau, Tevin C. Y., Keyser, Mikaela S., Da Silva, Jason A., Morris, Elysse K., Yordanov, Teodor E., Duscyz, Kinga P., Paterson, Scott, Yap, Alpha S., Hogan, Benjamin M. and Lagendijk, Anne Karine (2022). Dynamically regulated focal adhesions coordinate endothelial cell remodelling in developing vasculature. Development, 149 (23) dev200454, 1-14. doi: 10.1242/dev.200454

Regulating life after death: how mechanical communication mediates the epithelial response to apoptosis

Bonfim-Melo, Alexis, Duszyc, Kinga, Gomez, Guillermo A. and Yap, Alpha S. (2022). Regulating life after death: how mechanical communication mediates the epithelial response to apoptosis. The European Physical Journal E, 45 (1) 9, 9. doi: 10.1140/epje/s10189-022-00163-9

Live imaging of apoptotic extrusion and quantification of apical extrusion in epithelial cells

Duszyc, Kinga, Noordstra, Ivar, Yap, Alpha S and Gomez, Guillermo A (2021). Live imaging of apoptotic extrusion and quantification of apical extrusion in epithelial cells. Bio-protocol, 11 (22) e4232, e4232. doi: 10.21769/BioProtoc.4232

Enhanced RhoA signaling stabilizes E-cadherin in migrating epithelial monolayers

Gupta, Shafali, Duszyc, Kinga, Verma, Suzie, Budnar, Srikanth, Liang, Xuan, Gomez, Guillermo A., Marcq, Philippe, Noordstra, Ivar and Yap, Alpha S. (2021). Enhanced RhoA signaling stabilizes E-cadherin in migrating epithelial monolayers. Journal of Cell Science, 134 (17) jcs258767, 1-13. doi: 10.1242/jcs.258767

Mechanotransduction activates RhoA in the neighbors of apoptotic epithelial cells to engage apical extrusion

Duszyc, Kinga, Gomez, Guillermo A., Lagendijk, Anne K., Yau, Mei-Kwan, Nanavati, Bageshri Naimish, Gliddon, Briony L., Hall, Thomas E., Verma, Suzie, Hogan, Benjamin M., Pitson, Stuart M., Fairlie, David P., Parton, Robert G. and Yap, Alpha S. (2021). Mechanotransduction activates RhoA in the neighbors of apoptotic epithelial cells to engage apical extrusion. Current Biology, 31 (6), 1326-1336.e5. doi: 10.1016/j.cub.2021.01.003

Snail induces epithelial cell extrusion by regulating RhoA contractile signalling and cell–matrix adhesion

Wee, Kenneth, Hediyeh-Zadeh, Soroor, Duszyc, Kinga, Verma, Suzie, Nanavati, Bageshri N., Khare, Satyajeet, Varma, Amrita, Daly, Roger J., Yap, Alpha S., Davis, Melissa J. and Budnar, Srikanth (2020). Snail induces epithelial cell extrusion by regulating RhoA contractile signalling and cell–matrix adhesion. Journal of Cell Science, 133 (13) jcs235622, jcs235622. doi: 10.1242/jcs.235622

A mechanosensitive RhoA pathway that protects epithelia against acute tensile stress

Acharya, Bipul R., Nestor-Bergmann, Alexander, Liang, Xuan, Gupta, Shafali, Duszyc, Kinga, Gauquelin, Estelle, Gomez, Guillermo A., Budnar, Srikanth, Marcq, Philippe, Jensen, Oliver E., Bryant, Zev and Yap, Alpha S. (2018). A mechanosensitive RhoA pathway that protects epithelia against acute tensile stress. Developmental Cell, 47 (4), 439-452. doi: 10.1016/j.devcel.2018.09.016

Mechanosensing and mechanotransduction at cell-cell junctions

Yap, Alpha S., Duszyc, Kinga and Viasnoff, Virgile (2018). Mechanosensing and mechanotransduction at cell-cell junctions. Cold Spring Harbor Perspectives in Biology, 10 (8) a028761, a028761. doi: 10.1101/cshperspect.a028761

In life there is death: How epithelial tissue barriers are preserved despite the challenge of apoptosis

Duszyc, Kinga, Gomez, Guillermo A., Schroder, Kate, Sweet, Matthew J. and Yap, Alpha S. (2017). In life there is death: How epithelial tissue barriers are preserved despite the challenge of apoptosis. Tissue Barriers, 5 (4) e1345353, e1345353. doi: 10.1080/21688370.2017.1345353

ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens

Priya, Rashmi, Liang, Xuan, Teo, Jessica L., Duszyc, Kinga, Yap, Alpha S. and Gomez, Guillermo A. (2017). ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens. Molecular Biology of the Cell, 28 (1), 12-20. doi: 10.1091/mbc.E16-04-0262

Elimination of apoptotic epithelial cells: Regulation of apoptotic extrusion and immune responses to epithelial apoptosis

Duszyc, Kinga Patrycja (2019). Elimination of apoptotic epithelial cells: Regulation of apoptotic extrusion and immune responses to epithelial apoptosis. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. doi: 10.14264/uql.2019.709