The University of Queensland

Cytoskeleton and motors: complex cytoskeletal structures – cell–cell adhesion and the cytoskeleton

Nanavati, Bageshri N., Yap, Alpha S. and Noordstra, Ivar (2022). Cytoskeleton and motors: complex cytoskeletal structures – cell–cell adhesion and the cytoskeleton. Reference module in life sciences. (pp. Unknown-Unknown) Amsterdam, Netherlands: Elsevier. doi: 10.1016/b978-0-12-821618-7.00089-4

A truncation mutant of adenomatous polyposis coli impairs apical cell extrusion through elevated epithelial tissue tension

Gan, Wan J., Giri, Rabina, Begun, Jakob, Abud, Helen E., Hardeman, Edna C., Gunning, Peter W., Yap, Alpha S. and Noordstra, Ivar (2024). A truncation mutant of adenomatous polyposis coli impairs apical cell extrusion through elevated epithelial tissue tension. Cytoskeleton. doi: 10.1002/cm.21893

A Lifeact-EGFP quail for studying actin dynamics in vivo

Alvarez, Yanina D., van der Spuy, Marise, Wang, Jian Xiong, Noordstra, Ivar, Tan, Siew Zhuan, Carroll, Murron, Yap, Alpha S., Serralbo, Olivier and White, Melanie D. (2024). A Lifeact-EGFP quail for studying actin dynamics in vivo. Journal of Cell Biology, 223 (9) ARTN e202404066. doi: 10.1083/jcb.202404066

c-Src induced vascular malformations require localised matrix degradation at focal adhesions

Essebier, Patricia, Keyser, Mikaela, Yordanov, Teodor, Hill, Brittany, Yu, Alexander, Noordstra, Ivar, Yap, Alpha S., Stehbens, Samantha J., Lagendijk, Anne K., Schimmel, Lilian and Gordon, Emma J. (2024). c-Src induced vascular malformations require localised matrix degradation at focal adhesions. Journal of Cell Science, 137 (13) jcs262101. doi: 10.1242/jcs.262101

Adherens junctions as molecular regulators of emergent tissue mechanics

Campàs, Otger, Noordstra, Ivar and Yap, Alpha S. (2023). Adherens junctions as molecular regulators of emergent tissue mechanics. Nature Reviews Molecular Cell Biology, 25 (4), 252-269. doi: 10.1038/s41580-023-00688-7

Epithelial cell spreading assay on E-cadherin-coated glass or PDMS substrates for microscopy-based analysis of cadherin adhesions

Schimmel, Lilian and Noordstra, Ivar (2023). Epithelial cell spreading assay on E-cadherin-coated glass or PDMS substrates for microscopy-based analysis of cadherin adhesions. STAR Protocols, 4 (4) 102626. doi: 10.1016/j.xpro.2023.102626

An E-cadherin-actin clutch translates the mechanical force of cortical flow for cell-cell contact to inhibit epithelial cell locomotion

Noordstra, Ivar, Hermoso, Mario Díez, Schimmel, Lilian, Bonfim-Melo, Alexis, Currin-Ross, Denni, Duong, Cao Nguyen, Kalappurakkal, Joseph Mathew, Morris, Richard G., Vestweber, Dietmar, Mayor, Satyajit, Gordon, Emma, Roca-Cusachs, Pere and Yap, Alpha S. (2023). An E-cadherin-actin clutch translates the mechanical force of cortical flow for cell-cell contact to inhibit epithelial cell locomotion. Developmental Cell, 58 (18), 1748-1763.e6. doi: 10.1016/j.devcel.2023.06.011

Cadherins and the cortex: A matter of time?

Noordstra, Ivar, Morris, Richard G. and Yap, Alpha S. (2023). Cadherins and the cortex: A matter of time?. Current Opinion in Cell Biology, 80 102154, 102154. doi: 10.1016/j.ceb.2023.102154

Organization and dynamics of the cortical complexes controlling insulin secretion in β-cells

Noordstra, Ivar, van den Berg, Cyntha M., Boot, Fransje W J, Katrukha, Eugene A., Yu, Ka Lou, Tas, Roderick P., Portegies, Sybren, Viergever, Bastiaan J., de Graaff, Esther, Hoogenraad, Casper C., de Koning, Eelco J P, Carlotti, Françoise, Kapitein, Lukas C. and Akhmanova, Anna (2022). Organization and dynamics of the cortical complexes controlling insulin secretion in β-cells. Journal of cell science, 135 (3) jcs259430. doi: 10.1242/jcs.259430

Rapid lamellipodial responses by neighbor cells drive epithelial sealing in response to pyroptotic cell death

Bonfim-Melo, Alexis, Noordstra, Ivar, Gupta, Shafali, Chan, Amy H., Jones, Mathew J.K., Schroder, Kate and Yap, Alpha S. (2022). Rapid lamellipodial responses by neighbor cells drive epithelial sealing in response to pyroptotic cell death. Cell Reports, 38 (5) 110316, 110316. doi: 10.1016/j.celrep.2022.110316

Live imaging of apoptotic extrusion and quantification of apical extrusion in epithelial cells

Duszyc, Kinga, Noordstra, Ivar, Yap, Alpha S and Gomez, Guillermo A (2021). Live imaging of apoptotic extrusion and quantification of apical extrusion in epithelial cells. Bio-protocol, 11 (22) e4232, e4232. doi: 10.21769/BioProtoc.4232

Endothelial junctional membrane protrusions serve as hotspots for neutrophil transmigration

Arts, Janine J. G., Mahlandt, Eike K., Grönloh, Max, Schimmel, Lilian, Noordstra, Ivar, Gordon, Emma, van Steen, Abraham C.I., Tol, Simon, Walzog, Barbara, van Rijssel, Jos, Nolte, Martijn A., Postma, Marten, Khuon, Satya, Heddleston, John M., Wait, Eric, Chew, Teng Leong, Winter, Mark, Montanez, Eloi, Goedhart, Joachim and van Buul, Jaap D. (2021). Endothelial junctional membrane protrusions serve as hotspots for neutrophil transmigration. eLife, 10 e66074. doi: 10.7554/elife.66074

Enhanced RhoA signaling stabilizes E-cadherin in migrating epithelial monolayers

Gupta, Shafali, Duszyc, Kinga, Verma, Suzie, Budnar, Srikanth, Liang, Xuan, Gomez, Guillermo A., Marcq, Philippe, Noordstra, Ivar and Yap, Alpha S. (2021). Enhanced RhoA signaling stabilizes E-cadherin in migrating epithelial monolayers. Journal of Cell Science, 134 (17) jcs258767, 1-13. doi: 10.1242/jcs.258767

For whom the cell tolls

Noordstra, Ivar and Yap, Alpha S. (2021). For whom the cell tolls. Developmental Cell, 56 (11), 1555-1557. doi: 10.1016/j.devcel.2021.05.013

Caveolae control contractile tension for epithelia to eliminate tumor cells

Teo, Jessica L., Gomez, Guillermo A., Weeratunga, Saroja, Davies, Elizabeth M., Noordstra, Ivar, Budnar, Srikanth, Katsuno-Kambe, Hiroko, McGrath, Meagan J., Verma, Suzie, Tomatis, Vanesa, Acharya, Bipul R., Balasubramaniam, Lakshmi, Templin, Rachel M., McMahon, Kerrie-Ann, Lee, Yoke Seng, Ju, Robert J., Stebhens, Samantha J., Ladoux, Benoit, Mitchell, Christina A., Collins, Brett M., Parton, Robert G. and Yap, Alpha S. (2020). Caveolae control contractile tension for epithelia to eliminate tumor cells. Developmental Cell, 54 (1), 75-91.e7. doi: 10.1016/j.devcel.2020.05.002

TMEM59 potentiates Wnt signaling by promoting signalosome formation

Gerlach, Jan P., Jordens, Ingrid, Tauriello, Daniele V. F., Land-Kuper, Ineke van 't, Bugter, Jeroen M., Noordstra, Ivar, van der Kooij, Johanneke, Low, Teck Y., Pimentel-Muiños, Felipe X., Xanthakis, Despina, Fenderico, Nicola, Rabouille, Catherine, Heck, Albert J. R., Egan, David A. and Maurice, Madelon M. (2018). TMEM59 potentiates Wnt signaling by promoting signalosome formation. Proceedings of the National Academy of Sciences of the United States of America, 115 (17), E3996-E4005. doi: 10.1073/pnas.1721321115

Linking cortical microtubule attachment and exocytosis

Akhmanova, Anna and Noordstra, Ivar (2017). Linking cortical microtubule attachment and exocytosis. F1000Research, 6 469, 469. doi: 10.12688/f1000research.10729.1

Mesenchymal cell invasion requires cooperative regulation of persistent microtubule growth by SLAIN2 and CLASP1

Bouchet, Benjamin P., Noordstra, Ivar, van Amersfoort, Miranda, Katrukha, Eugene A., Ammon, York-Christoph, ter Hoeve, Natalie D., Hodgson, Louis, Dogterom, Marileen, Derksen, Patrick W. B. and Akhmanova, Anna (2016). Mesenchymal cell invasion requires cooperative regulation of persistent microtubule growth by SLAIN2 and CLASP1. Developmental Cell, 39 (6), 708-723. doi: 10.1016/j.devcel.2016.11.009

Molecular pathway of microtubule organization at the golgi apparatus

Wu, Jingchao, de Heus, Cecilia, Liu, Qingyang, Bouchet, Benjamin P., Noordstra, Ivar, Jiang, Kai, Hua, Shasha, Martin, Maud, Yang, Chao, Grigoriev, Ilya, Katrukha, Eugene A., Altelaar, A. F. Maarten, Hoogenraad, Casper C., Qi, Robert Z., Klumperman, Judith and Akhmanova, Anna (2016). Molecular pathway of microtubule organization at the golgi apparatus. Developmental Cell, 39 (1), 44-60. doi: 10.1016/j.devcel.2016.08.009

Control of apico-basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7

Noordstra, Ivar, Liu, Qingyang, Nijenhuis, Wilco, Hua, Shasha, Jiang, Kai, Baars, Matthijs, Remmelzwaal, Sanne, Martin, Maud, Kapitein, Lukas C. and Akhmanova, Anna (2016). Control of apico-basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7. Journal of Cell Science, 129 (22), 4278-4288. doi: 10.1242/jcs.194878