Dr Stefan Emming


Institute for Molecular Bioscience


Stefan has a long-standing interest in trying to understand cellular processes at a detailed molecular level. He did his Master in Biochemistry in a Structural Biology lab, investigating the structure and function of the intracellular innate immune sensors AIM2 and STING. Following a short period at the Biozentrum in Basel (Switzerland), Stefan joined the Molecular Immunology lab of S. Monticelli at the Institute for Research in Biomedicine (Bellinzona, Switzerland) to conduct a PhD. After a deep dive into transcriptional and post-transcriptional regulation of gene expression in T cells during his PhD, Stefan joined the Inflammasome Lab in 2019 as a Postdoctoral Research Officer and was awarded an ARC DECRA fellowship starting in 2022. His research is focused on the multi-step mechanism of inflammasome activation and its regulation on a molecular level


  • Doctor of Philosophy, University of Bern


  • Coombs, Jared R., Zamoshnikova, Alina, Holley, Caroline L., Maddugoda, Madhavi P., Teo, Daniel Eng Thiam, Chauvin, Camille, Poulin, Lionel F, Vitak, Nazarii, Ross, Connie M., Mellacheruvu, Manasa, Coll, Rebecca C., Heinz, Leonhard X., Burgener, Sabrina S., Emming, Stefan, Chamaillard, Mathias, Boucher, Dave and Schroder, Kate (2024). NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome. Science Signaling, 17 (820) abg8145, eabg8145. doi: 10.1126/scisignal.abg8145

  • Yap, Jeremy KY, Emming, Stefan and Schroder, Kate (2023). Oxidized thioredoxin 1 places a leash on NLRP1 inflammasome activity. Immunology & Cell Biology, 102 (1), 5-7. doi: 10.1111/imcb.12710

  • Mellacheruvu, Manasa, Lawrence, Grace M. E. P., Emming, Stefan and Schroder, Kate (2023). Reversing the mitochondrial hex that bewitches NLRP3. Science Immunology, 8 (84) eadh2967, 1-4. doi: 10.1126/sciimmunol.adh2967

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  • Doctor Philosophy

  • Doctor Philosophy

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Book Chapter

  • Emming, Stefan, Monteleone, Mercedes M., Kambara, Hiroto, Starchenko, Alina, Alley, Jennifer, Nolan, Michael A., Li, Wei, Kilty, Iain and Schroder, Kate (2023). Quantifying Cell Death Induced by the NLRC4 Inflammasome. NLR Proteins: Methods and Protocols. (pp. 199-210) New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-3350-2_13

Journal Article

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision