The University of Queensland

Mesoniviruses (Mesoniviridae)

Hobson-Peters, Jody and Watterson, Daniel (2021). Mesoniviruses (Mesoniviridae). Encyclopedia of Virology. (pp. 804-807) Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-12-814515-9.00007-2

Plugging the leak in Dengue shock

Watterson, Daniel, Modhiran, Naphak, Muller, David A., Stacey, Katryn J. and Young, Paul R. (2018). Plugging the leak in Dengue shock. Dengue and Zika: Control and Antiviral Treatment Strategies. (pp. 89-106) edited by Rolf Hilgenfeld and Subhash G. Vasudevan. Singapore, Singapore: Springer Nature. doi: 10.1007/978-981-10-8727-1_7

Enhancement of cellular immunity following needle-free vaccination of mice with SARS-CoV-2 spike protein

McMillan, Christopher L. D., Wijesundara, Danushka K., Choo, Jovin J. Y., Amarilla, Alberto A., Modhiran, Naphak, Fernando, Germain J. P., Khromykh, Alexander A., Watterson, Daniel, Young, Paul R. and Muller, David A. (2024). Enhancement of cellular immunity following needle-free vaccination of mice with SARS-CoV-2 spike protein. Journal of General Virology, 105 (1), 1-6. doi: 10.1099/jgv.0.001947

The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 gamma variant

Pegg, Cassandra L., Modhiran, Naphak, Parry, Rhys H., Liang, Benjamin, Amarilla, Alberto A., Khromykh, Alexander A., Burr, Lucy, Young, Paul R., Chappell, Keith, Schulz, Benjamin L. and Watterson, Daniel (2023). The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 gamma variant. Glycobiology cwad097, 1-13. doi: 10.1093/glycob/cwad097

Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

Aguado, Julio, Amarilla, Alberto A., Taherian Fard, Atefeh, Albornoz, Eduardo A., Tyshkovskiy, Alexander, Schwabenland, Marius, Chaggar, Harman K., Modhiran, Naphak, Gómez-Inclán, Cecilia, Javed, Ibrahim, Baradar, Alireza A., Liang, Benjamin, Peng, Lianli, Dharmaratne, Malindrie, Pietrogrande, Giovanni, Padmanabhan, Pranesh, Freney, Morgan E., Parry, Rhys, Sng, Julian D. J., Isaacs, Ariel, Khromykh, Alexander A., Valenzuela Nieto, Guillermo, Rojas-Fernandez, Alejandro, Davis, Thomas P., Prinz, Marco, Bengsch, Bertram, Gladyshev, Vadim N., Woodruff, Trent M., Mar, Jessica C. ... Wolvetang, Ernst J. (2023). Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology. Nature Aging, 3 (12), 1-15. doi: 10.1038/s43587-023-00519-6

Long-term safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2 in adults aged 18–55 years or ≥56 years: 12-month results from a randomised, double-blind, placebo-controlled, phase 1 trial

Chappell, Keith J., Mordant, Francesca L., Amarilla, Alberto A., Modhiran, Naphak, Liang, Benjamin, Li, Zheyi, Wijesundara, Danushka K., Lackenby, Julia A., Griffin, Paul, Bennet, Jillian K., Hensen, Luca, Zhang, Wuji, Nguyen, Thi H.O., Tran, Mai H., Tapley, Peter, Barnes, James, Reading, Patrick C., Kedzierska, Katherine, Ranasinghe, Charani, Subbarao, Kanta, Watterson, Daniel, Young, Paul R. and Munro, Trent P. (2023). Long-term safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2 in adults aged 18–55 years or ≥56 years: 12-month results from a randomised, double-blind, placebo-controlled, phase 1 trial. eBioMedicine, 97 104842, 104842. doi: 10.1016/j.ebiom.2023.104842

Kinetics of severe dengue virus infection and development of gut pathology in mice

Pliego Zamora, Adriana, Kim, Jaehyeon, Vajjhala, Parimala R., Thygesen, Sara J., Watterson, Daniel, Modhiran, Naphak, Bielefeldt-Ohmann, Helle and Stacey, Katryn J. (2023). Kinetics of severe dengue virus infection and development of gut pathology in mice. Journal of Virology, 97 (11) ARTN e0125123, e0125123. doi: 10.1128/jvi.01251-23

Cubane and cyclooctatetraene pirfenidones – synthesis and biological evaluation

Liu, Yizhou, Wen Liang, Benjamin Jian, Modhiran, Naphak, Savage, G. Paul, Watterson, Daniel and Williams, Craig M. (2023). Cubane and cyclooctatetraene pirfenidones – synthesis and biological evaluation. Asian Journal of Organic Chemistry, 12 (8) e202300238, 1-7. doi: 10.1002/ajoc.202300238

A nanobody recognizes a unique conserved epitope and potently neutralizes against the SARS-CoV-2 omicron variants

Modhiran, Naphak, Lauer, Simon Malte, Amarilla, Alberto A., Hewins, Peter, Lopes van den Broek, Sara Irene, Low, Yu Shang, Thakur, Nazia, Liang, Benjamin, Nieto, Guillermo Valenzuela, Jung, James, Paramitha, Devina, Isaacs, Ariel, Sng, Julian D. J., Song, David, Jørgensen, Jesper Tranekjær, Cheuquemilla, Yorka, Bürger, Jörg, Andersen, Ida Vang, Himelreichs, Johanna, Jara, Ronald, MacLoughlin, Ronan, Miranda-Chacon, Zaray, Chana-Cuevas, Pedro, Kramer, Vasko, Spahn, Christian M. T., Mielke, Thorsten, Khromykh, Alexander A., Munro, Trent, Jones, Martina L. ... Watterson, Daniel (2023). A nanobody recognizes a unique conserved epitope and potently neutralizes against the SARS-CoV-2 omicron variants. iScience, 26 (7) 107085, 107085. doi: 10.1016/j.isci.2023.107085

Structure and antigenicity of divergent Henipavirus fusion glycoproteins

Isaacs, Ariel, Low, Yu Shang, Macauslane, Kyle L., Seitanidou, Joy, Pegg, Cassandra L., Cheung, Stacey T. M., Liang, Benjamin, Scott, Connor A. P., Landsberg, Michael J., Schulz, Benjamin L., Chappell, Keith J., Modhiran, Naphak and Watterson, Daniel (2023). Structure and antigenicity of divergent Henipavirus fusion glycoproteins. Nature Communications, 14 (1) 3577, 1-10. doi: 10.1038/s41467-023-39278-8

Inactivation of SARS‐CoV ‐2 infectivity in platelet concentrates or plasma following treatment with ultraviolet C light or with methylene blue combined with visible light

Hobson‐Peters, Jody, Amarilla, Alberto A., Rustanti, Lina, Marks, Denese C., Roulis, Eileen, Khromykh, Alexander A., Modhiran, Naphak, Watterson, Daniel, Reichenberg, Stefan, Tolksdorf, Frank, Sumian, Chryslain, Seltsam, Axel, Gravemann, Ute and Faddy, Helen M. (2023). Inactivation of SARS‐CoV ‐2 infectivity in platelet concentrates or plasma following treatment with ultraviolet C light or with methylene blue combined with visible light. Transfusion, 63 (2), 288-293. doi: 10.1111/trf.17238

SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

Albornoz, Eduardo A., Amarilla, Alberto A., Modhiran, Naphak, Parker, Sandra, Li, Xaria X., Wijesundara, Danushka K., Aguado, Julio, Zamora, Adriana Pliego, McMillan, Christopher L. D., Liang, Benjamin, Peng, Nias Y. G., Sng, Julian D. J., Saima, Fatema Tuj, Fung, Jenny N., Lee, John D., Paramitha, Devina, Parry, Rhys, Avumegah, Michael S., Isaacs, Ariel, Lo, Martin W., Miranda-Chacon, Zaray, Bradshaw, Daniella, Salinas-Rebolledo, Constanza, Rajapakse, Niwanthi W., Wolvetang, Ernst J., Munro, Trent P., Rojas-Fernandez, Alejandro, Young, Paul R., Stacey, Katryn J. ... Woodruff, Trent M. (2023). SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein. Molecular Psychiatry, 28 (7), 2878-2893. doi: 10.1038/s41380-022-01831-0

Monoclonal antibodies specific for SARS-CoV-2 spike protein suitable for multiple applications for current variants of concern

Morgan, Mahali S., Yan, Kexin, Le, Thuy T., Johnston, Ryan A., Amarilla, Alberto A., Muller, David A., McMillan, Christopher L. D., Modhiran, Naphak, Watterson, Daniel, Potter, James R., Sng, Julian D. J., Lor, Mary, Paramitha, Devina, Isaacs, Ariel, Khromykh, Alexander A., Hall, Roy A., Suhrbier, Andreas, Rawle, Daniel J. and Hobson-Peters, Jody (2022). Monoclonal antibodies specific for SARS-CoV-2 spike protein suitable for multiple applications for current variants of concern. Viruses, 15 (1) 139, 1-18. doi: 10.3390/v15010139

Zika virus noncoding RNA cooperates with the viral protein NS5 to inhibit STAT1 phosphorylation and facilitate viral pathogenesis

Slonchak, Andrii, Wang, Xiaohui, Aguado, Julio, Sng, Julian D. J., Chaggar, Harman, Freney, Morgan E., Yan, Kexin, Torres, Francisco J., Amarilla, Alberto A., Balea, Rickyle, Setoh, Yin Xiang, Peng, Nias, Watterson, Daniel, Wolvetang, Ernst, Suhrbier, Andreas and Khromykh, Alexander A. (2022). Zika virus noncoding RNA cooperates with the viral protein NS5 to inhibit STAT1 phosphorylation and facilitate viral pathogenesis. Science Advances, 8 (48) eadd8095, eadd8095. doi: 10.1126/sciadv.add8095

Development and evaluation of an 18F-labeled nanobody to target SARS-CoV-2's spike protein

Lopes van den Broek, Sara, García-Vázquez, Rocío, Andersen, Ida Vang, Valenzuela-Nieto, Guillermo, Shalgunov, Vladimir, Battisti, Umberto M., Schwefel, David, Modhiran, Naphak, Kramer, Vasko, Cheuquemilla, Yorka, Jara, Ronald, Salinas-Varas, Constanza, Amarilla, Alberto A., Watterson, Daniel, Rojas-Fernandez, Alejandro and Herth, Matthias M. (2022). Development and evaluation of an 18F-labeled nanobody to target SARS-CoV-2's spike protein. Frontiers in Nuclear Medicine, 2 1033697. doi: 10.3389/fnume.2022.1033697

Characterization and comparison of novel adjuvants for a prefusion clamped MERS vaccine

O’Donnell, Jake S., Isaacs, Ariel, Jakob, Virginie, Lebas, Celia, Barnes, James B., Reading, Patrick C., Young, Paul R., Watterson, Daniel, Dubois, Patrice M., Collin, Nicolas and Chappell, Keith J. (2022). Characterization and comparison of novel adjuvants for a prefusion clamped MERS vaccine. Frontiers in Immunology, 13 976968, 976968. doi: 10.3389/fimmu.2022.976968

A platform technology for generating subunit vaccines against diverse viral pathogens

Young, Andrew, Isaacs, Ariel, Scott, Connor A. P., Modhiran, Naphak, McMillan, Christopher L. D., Cheung, Stacey T. M., Barr, Jennifer, Marsh, Glenn, Thakur, Nazia, Bailey, Dalan, Li, Kenneth S. M., Luk, Hayes K. H., Kok, Kin-Hang, Lau, Susanna K. P., Woo, Patrick C. Y., Furuyama, Wakako, Marzi, Andrea, Young, Paul R., Chappell, Keith J. and Watterson, Daniel (2022). A platform technology for generating subunit vaccines against diverse viral pathogens. Frontiers in Immunology, 13 963023, 1-16. doi: 10.3389/fimmu.2022.963023

Skin-patch delivered subunit vaccine induces broadly neutralising antibodies against SARS-CoV-2 variants of concern

McMillan, Christopher L.D., Amarilla, Alberto A., Modhiran, Naphak, Choo, Jovin J.Y., Azuar, Armira, Honeyman, Kate E., Khromykh, Alexander A., Young, Paul R., Watterson, Daniel and Muller, David A. (2022). Skin-patch delivered subunit vaccine induces broadly neutralising antibodies against SARS-CoV-2 variants of concern. Vaccine, 40 (34), 4929-4932. doi: 10.1016/j.vaccine.2022.07.013

SARS-CoV-2 triggers complement activation through interactions with heparan sulfate

Lo, Martin W., Amarilla, Alberto A., Lee, John D., Albornoz, Eduardo A., Modhiran, Naphak, Clark, Richard J., Ferro, Vito, Chhabra, Mohit, Khromykh, Alexander A., Watterson, Daniel and Woodruff, Trent M. (2022). SARS-CoV-2 triggers complement activation through interactions with heparan sulfate. Clinical and Translational Immunology, 11 (8) e1413, e1413. doi: 10.1002/cti2.1413

Nucleocapsid specific diagnostics for the detection of divergent SARS-CoV-2 variants

Isaacs, Ariel, Amarilla, Alberto A., Aguado, Julio, Modhiran, Naphak, Albornoz, Eduardo A., Baradar, Alireza A., McMillan, Christopher L. D., Choo, Jovin J. Y., Idris, Adi, Supramaniam, Aroon, McMillan, Nigel A. J., Muller, David A., Young, Paul R., Woodruff, Trent M., Wolvetang, Ernst J., Chappell, Keith J. and Watterson, Daniel (2022). Nucleocapsid specific diagnostics for the detection of divergent SARS-CoV-2 variants. Frontiers in Immunology, 13 926262, 926262. doi: 10.3389/fimmu.2022.926262

The distinguishing NS5-M114V mutation in American Zika virus isolates has negligible impacts on virus replication and transmission potential

Peng, Nias Y. G., Amarilla, Alberto A., Hugo, Leon E., Modhiran, Naphak, Sng, Julian D. J., Slonchak, Andrii, Watterson, Daniel, Setoh, Yin Xiang and Khromykh, Alexander A. (2022). The distinguishing NS5-M114V mutation in American Zika virus isolates has negligible impacts on virus replication and transmission potential. PLoS Neglected Tropical Diseases, 16 (5) e0010426, 1-17. doi: 10.1371/journal.pntd.0010426

Absence of anti-RBD antibodies in SARS-CoV-2 infected or naive individuals prior to vaccination with CoronaVac leads to short protection of only four months duration

Oliveira, Camille F. de, Neto, Walter F. F., Silva, Carla P. da, Ribeiro, Ana Claudia S., Martins, Lívia C., Sousa, Alana W. de, Freitas, Maria N. O., Chiang, Jannifer O., Silva, Franko A., Santos, Eder B. dos, Medeiros, Daniele B. A., Pinheiro, Gleiciane S., Brandão, Gleiciane F., Carvalho, Valéria L., Azevedo, Raimunda S. S., Vasconcelos, Pedro F. C., Costa, Igor B., Costa, Iran B., Santos, Mirleide C. dos, Soares, Luana S., Bedran, Rayssa L. S., Ferreira, James L., Amarilla, Alberto A., Modhiran, Naphak, McMillan, Christopher L. D., Freney, Morgan E., Muller, David A., Watterson, Daniel, Casseb, Lívia M. N. and Henriques, Daniele F. (2022). Absence of anti-RBD antibodies in SARS-CoV-2 infected or naive individuals prior to vaccination with CoronaVac leads to short protection of only four months duration. Vaccines, 10 (5) 690. doi: 10.3390/vaccines10050690

Peptide-based vaccine against SARS-CoV-2: peptide antigen discovery and screening of adjuvant systems

Shalash, Ahmed O., Azuar, Armira, Madge, Harrison Y. R., Modhiran, Naphak, Amarilla, Alberto A., Liang, Benjamin, Khromykh, Alexander A., Hussein, Waleed M., Chappell, Keith J., Watterson, Daniel, Young, Paul R., Skwarczynski, Mariusz and Toth, Istvan (2022). Peptide-based vaccine against SARS-CoV-2: peptide antigen discovery and screening of adjuvant systems. Pharmaceutics, 14 (4) 856, 856. doi: 10.3390/pharmaceutics14040856

Dermal delivery of a SARS-CoV-2 subunit vaccine induces immunogenicity against variants of concern

McMillan, Christopher L. D., Azuar, Armira, Choo, Jovin J. Y., Modhiran, Naphak, Amarilla, Alberto A., Isaacs, Ariel, Honeyman, Kate E., Cheung, Stacey T. M., Liang, Benjamin, Wurm, Maria J., Pino, Paco, Kint, Joeri, Fernando, Germain J. P., Landsberg, Michael J., Khromykh, Alexander A., Hobson-Peters, Jody, Watterson, Daniel, Young, Paul R. and Muller, David A. (2022). Dermal delivery of a SARS-CoV-2 subunit vaccine induces immunogenicity against variants of concern. Vaccines, 10 (4) 578, 578. doi: 10.3390/vaccines10040578

Synthetic heparan sulfate mimetic pixatimod (PG545) potently inhibits SARS-CoV-2 by disrupting the spike–ACE2 interaction

Guimond, Scott E., Mycroft-West, Courtney J., Gandhi, Neha S., Tree, Julia A., Le, Thuy T., Spalluto, C. Mirella, Humbert, Maria V., Buttigieg, Karen R., Coombes, Naomi, Elmore, Michael J., Wand, Matthew, Nyström, Kristina, Said, Joanna, Setoh, Yin Xiang, Amarilla, Alberto A., Modhiran, Naphak, Sng, Julian D. J., Chhabra, Mohit, Young, Paul R., Rawle, Daniel J., Lima, Marcelo A., Yates, Edwin A., Karlsson, Richard, Miller, Rebecca L., Chen, Yen-Hsi, Bagdonaite, Ieva, Yang, Zhang, Stewart, James, Nguyen, Dung ... Turnbull, Jeremy E. (2022). Synthetic heparan sulfate mimetic pixatimod (PG545) potently inhibits SARS-CoV-2 by disrupting the spike–ACE2 interaction. ACS Central Science, 8 (5) acscentsci.1c01293, 527-545. doi: 10.1021/acscentsci.1c01293

Author Correction: Development of molecular clamp stabilized hemagglutinin vaccines for Influenza A viruses

McMillan, Christopher L. D., Cheung, Stacey T. M., Modhiran, Naphak, Barnes, James, Amarilla, Alberto A., Bielefeldt-Ohmann, Helle, Lee, Leo Yi Yang, Guilfoyle, Kate, van Amerongen, Geert, Stittelaar, Koert, Jakob, Virginie, Lebas, Celia, Reading, Patrick, Short, Kirsty R., Young, Paul R., Watterson, Daniel and Chappell, Keith J. (2022). Author Correction: Development of molecular clamp stabilized hemagglutinin vaccines for Influenza A viruses. npj Vaccines, 7 (1) 3, 3. doi: 10.1038/s41541-021-00428-y

Detection and quantification of SARS-CoV-2 receptor binding domain neutralization by a sensitive competitive ELISA assay

Shalash, Ahmed O., Azuar, Armira, Madge, Harrison Y. R., Modhiran, Naphak, Amarilla, Alberto A., Liang, Benjamin, Khromykh, Alexander A., Watterson, Daniel, Young, Paul R., Toth, Istvan and Skwarczynski, Mariusz (2021). Detection and quantification of SARS-CoV-2 receptor binding domain neutralization by a sensitive competitive ELISA assay. Vaccines, 9 (12) 1493, 1-21. doi: 10.3390/vaccines9121493

Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity nanobody

Valenzuela Nieto, Guillermo, Jara, Ronald, Watterson, Daniel, Modhiran, Naphak, Amarilla, Alberto A., Himelreichs, Johanna, Khromykh, Alexander A., Salinas-Rebolledo, Constanza, Pinto, Teresa, Cheuquemilla, Yorka, Margolles, Yago, López González del Rey, Natalia, Miranda-Chacon, Zaray, Cuevas, Alexei, Berking, Anne, Deride, Camila, González-Moraga, Sebastián, Mancilla, Héctor, Maturana, Daniel, Langer, Andreas, Toledo, Juan Pablo, Müller, Ananda, Uberti, Benjamín, Krall, Paola, Ehrenfeld, Pamela, Blesa, Javier, Chana-Cuevas, Pedro, Rehren, German, Schwefel, David ... Rojas-Fernandez, Alejandro (2021). Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity nanobody. Scientific Reports, 11 (1) 3318, 3318. doi: 10.1038/s41598-021-82833-w

Systems serology detects functionally distinct coronavirus antibody features in children and elderly

Selva, Kevin J., van de Sandt, Carolien E., Lemke, Melissa M., Lee, Christina Y., Shoffner, Suzanne K., Chua, Brendon Y., Davis, Samantha K., Nguyen, Thi H. O., Rowntree, Louise C., Hensen, Luca, Koutsakos, Marios, Wong, Chinn Yi, Mordant, Francesca, Jackson, David C., Flanagan, Katie L., Crowe, Jane, Tosif, Shidan, Neeland, Melanie R., Sutton, Philip, Licciardi, Paul V., Crawford, Nigel W., Cheng, Allen C., Doolan, Denise L., Amanat, Fatima, Krammer, Florian, Chappell, Keith, Modhiran, Naphak, Watterson, Daniel, Young, Paul ... Chung, Amy W. (2021). Systems serology detects functionally distinct coronavirus antibody features in children and elderly. Nature Communications, 12 (1) 2037, 2037. doi: 10.1038/s41467-021-22236-7

Development of molecular clamp stabilized hemagglutinin vaccines for Influenza A viruses

McMillan, Christopher L. D., Cheung, Stacey T. M., Modhiran, Naphak, Barnes, James, Amarilla, Alberto A., Bielefeldt-Ohmann, Helle, Lee, Leo Yi Yang, Guilfoyle, Kate, van Amerongen, Geert, Stittelaar, Koert, Jakob, Virginie, Lebas, Celia, Reading, Patrick, Short, Kirsty R., Young, Paul R., Watterson, Daniel and Chappell, Keith J. (2021). Development of molecular clamp stabilized hemagglutinin vaccines for Influenza A viruses. npj Vaccines, 6 (1) 135, 135. doi: 10.1038/s41541-021-00395-4

Complete protection by a single-dose skin patch–delivered SARS-CoV-2 spike vaccine

McMillan, Christopher L. D., Choo, Jovin J. Y., Idris, Adi, Supramaniam, Aroon, Modhiran, Naphak, Amarilla, Alberto A., Isaacs, Ariel, Cheung, Stacey T. M., Liang, Benjamin, Bielefeldt-Ohmann, Helle, Azuar, Armira, Acharya, Dhruba, Kelly, Gabrielle, Fernando, Germain J. P., Landsberg, Michael J., Khromykh, Alexander A., Watterson, Daniel, Young, Paul R., McMillan, Nigel A. J. and Muller, David A. (2021). Complete protection by a single-dose skin patch–delivered SARS-CoV-2 spike vaccine. Science Advances, 7 (44) eabj8065, eabj8065. doi: 10.1126/sciadv.abj8065

Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial

Chappell, Keith J., Mordant, Francesca L., Li, Zheyi, Wijesundara, Danushka K., Ellenberg, Paula, Lackenby, Julia A., Cheung, Stacey T. M., Modhiran, Naphak, Avumegah, Michael S., Henderson, Christina L., Hoger, Kym, Griffin, Paul, Bennet, Jillian, Hensen, Luca, Zhang, Wuji, Nguyen, Thi H. O., Marrero-Hernandez, Sara, Selva, Kevin J., Chung, Amy W., Tran, Mai H., Tapley, Peter, Barnes, James, Reading, Patrick C., Nicholson, Suellen, Corby, Stavroula, Holgate, Thomas, Wines, Bruce D., Hogarth, P Mark, Kedzierska, Katherine ... Munro, Trent P. (2021). Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial. The Lancet Infectious Diseases, 21 (10), 1383-1394. doi: 10.1016/S1473-3099(21)00200-0

Combinatorial F-G Immunogens as Nipah and Respiratory Syncytial Virus Vaccine Candidates

Isaacs, Ariel, Cheung, Stacey T. M., Thakur, Nazia, Jaberolansar, Noushin, Young, Andrew, Modhiran, Naphak, Bailey, Dalan, Graham, Simon P., Young, Paul R., Chappell, Keith J. and Watterson, Daniel (2021). Combinatorial F-G Immunogens as Nipah and Respiratory Syncytial Virus Vaccine Candidates. Viruses, 13 (10) 1942. doi: 10.3390/v13101942

Cord‐blood respiratory syncytial virus antibodies and respiratory health in first 5‐years of life

Takashima, Mari D., Grimwood, Keith, Sly, Peter D., Lambert, Stephen B., Chappell, Keith J., Watterson, Daniel, Young, Paul, Kusel, Merci, Holt, Barbara, Holt, Patrick and Ware, Robert S. (2021). Cord‐blood respiratory syncytial virus antibodies and respiratory health in first 5‐years of life. Pediatric Pulmonology, 56 (12), 3942-3951. doi: 10.1002/ppul.25688

Implications of dengue virus maturation on vaccine induced humoral immunity in mice

Scott, Connor A. P., Amarilla, Alberto A., Bibby, Summa, Newton, Natalee D., Hall, Roy A., Hobson-Peters, Jody, Muller, David A., Chappell, Keith J., Young, Paul R., Modhiran, Naphak and Watterson, Daniel (2021). Implications of dengue virus maturation on vaccine induced humoral immunity in mice. Viruses, 13 (9) 1843, 1843. doi: 10.3390/v13091843

No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing

Smits, Nathan, Rasmussen, Jay, Bodea, Gabriela O., Amarilla, Alberto A., Gerdes, Patricia, Sanchez-Luque, Francisco J., Ajjikuttira, Prabha, Modhiran, Naphak, Liang, Benjamin, Faivre, Jamila, Deveson, Ira W., Khromykh, Alexander A., Watterson, Daniel, Ewing, Adam D. and Faulkner, Geoffrey J. (2021). No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing. Cell Reports, 36 (7) 109530, 109530. doi: 10.1016/j.celrep.2021.109530

Current knowledge of COVID-19: advances, challenges and future perspectives

Wu, Yuhan, Peng, Zhuobing, Yan, Yongxue, Hu, Jintao, Wang, Yalong, Wang, Xiaoyu, Peng, Ruchao, Watterson, Daniel and Shi, Yi (2021). Current knowledge of COVID-19: advances, challenges and future perspectives. Biosafety and Health, 3 (4), 202-209. doi: 10.1016/j.bsheal.2021.06.001

ACE2-lentiviral transduction enables mouse SARS-CoV-2 infection and mapping of receptor interactions

Rawle, Daniel J., Le, Thuy T., Dumenil, Troy, Yan, Kexin, Tang, Bing, Nguyen, Wilson, Watterson, Daniel, Modhiran, Naphak, Hobson-Peters, Jody, Bishop, Cameron and Suhrbier, Andreas (2021). ACE2-lentiviral transduction enables mouse SARS-CoV-2 infection and mapping of receptor interactions. PLoS Pathogens, 17 (7) e1009723, 1-37. doi: 10.1371/journal.ppat.1009723

A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses

Amarilla, Alberto A., Sng, Julian D. J., Parry, Rhys, Deerain, Joshua M., Potter, James R., Setoh, Yin Xiang, Rawle, Daniel J., Le, Thuy T., Modhiran, Naphak, Wang, Xiaohui, Peng, Nias Y. G., Torres, Francisco J., Pyke, Alyssa, Harrison, Jessica J., Freney, Morgan E., Liang, Benjamin, McMillan, Christopher L. D., Cheung, Stacey T. M., Guevara, Darwin J Da Costa, Hardy, Joshua M., Bettington, Mark, Muller, David A., Coulibaly, Fasséli, Moore, Frederick, Hall, Roy A., Young, Paul R., Mackenzie, Jason M., Hobson-Peters, Jody, Suhrbier, Andreas ... Khromykh, Alexander A. (2021). A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses. Nature Communications, 12 (1) 3431, 3431. doi: 10.1038/s41467-021-23779-5

A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses

Hardy, Joshua M., Newton, Natalee D., Modhiran, Naphak, Scott, Connor A. P., Venugopal, Hariprasad, Vet, Laura J., Young, Paul R., Hall, Roy A., Hobson-Peters, Jody, Coulibaly, Fasséli and Watterson, Daniel (2021). A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses. Nature Communications, 12 (1) 3266, 3266. doi: 10.1038/s41467-021-22773-1

A chimeric dengue virus vaccine candidate delivered by high density microarray patches protects against infection in mice

Choo, Jovin J. Y., Vet, Laura J., McMillan, Christopher L. D., Harrison, Jessica J., Scott, Connor A. P., Depelsenaire, Alexandra C. I., Fernando, Germain J. P., Watterson, Daniel, Hall, Roy A., Young, Paul R., Hobson-Peters, Jody and Muller, David A. (2021). A chimeric dengue virus vaccine candidate delivered by high density microarray patches protects against infection in mice. npj Vaccines, 6 (1) 66, 66. doi: 10.1038/s41541-021-00328-1

Assessing the potential of unmanned aerial vehicle spraying of aqueous ozone as an outdoor disinfectant for SARS-CoV-2

Albert, Simon, Amarilla, Alberto A., Trollope, Ben, Sng, Julian D.J., Setoh, Yin Xiang, Deering, Nathaniel, Modhiran, Naphak, Weng, Sung-Hsia, Melo, Maria C., Hutley, Nicholas, Nandy, Avik, Furlong, Michael J., Young, Paul R., Watterson, Daniel, Grinham, Alistair R. and Khromykh, Alexander A. (2021). Assessing the potential of unmanned aerial vehicle spraying of aqueous ozone as an outdoor disinfectant for SARS-CoV-2. Environmental Research, 196 110944, 110944. doi: 10.1016/j.envres.2021.110944

The structure of an infectious immature flavivirus redefines viral architecture and maturation

Newton, Natalee D., Hardy, Joshua M., Modhiran, Naphak, Hugo, Leon E., Amarilla, Alberto A., Bibby, Summa, Venugopal, Hariprasad, Harrison, Jessica J., Traves, Renee J., Hall, Roy A., Hobson-Peters, Jody, Coulibaly, Fasséli and Watterson, Daniel (2021). The structure of an infectious immature flavivirus redefines viral architecture and maturation. Science Advances, 7 (20) eabe4507, 1-12. doi: 10.1126/sciadv.abe4507

Preclinical development of a molecular clamp-stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2

Watterson, Daniel, Wijesundara, Danushka K., Modhiran, Naphak, Mordant, Francesca L., Li, Zheyi, Avumegah, Michael S., McMillan, Christopher L. D., Lackenby, Julia, Guilfoyle, Kate, van Amerongen, Geert, Stittelaar, Koert, Cheung, Stacey T. M., Bibby, Summa, Daleris, Mallory, Hoger, Kym, Gillard, Marianne, Radunz, Eve, Jones, Martina L., Hughes, Karen, Hughes, Ben, Goh, Justin, Edwards, David, Scoble, Judith, Pearce, Lesley, Kowalczyk, Lukasz, Phan, Tram, La, Mylinh, Lu, Louis, Pham, Tam ... Chappell, Keith J. (2021). Preclinical development of a molecular clamp-stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2. Clinical & Translational Immunology, 10 (4) e1269, e1269. doi: 10.1002/cti2.1269

Discovery of sisunatovir (RV521), an inhibitor of respiratory syncytial virus fusion

Cockerill, G. Stuart, Angell, Richard M., Bedernjak, Alexandre, Chuckowree, Irina, Fraser, Ian, Gascon-Simorte, Jose, Gilman, Morgan S. A., Good, James A. D., Harland, Rachel, Johnson, Sara M., Ludes-Meyers, John H., Littler, Edward, Lumley, James, Lunn, Graham, Mathews, Neil, McLellan, Jason S., Paradowski, Michael, Peeples, Mark E., Scott, Claire, Tait, Dereck, Taylor, Geraldine, Thom, Michelle, Thomas, Elaine, Villalonga Barber, Carol, Ward, Simon E., Watterson, Daniel, Williams, Gareth, Young, Paul and Powell, Kenneth (2021). Discovery of sisunatovir (RV521), an inhibitor of respiratory syncytial virus fusion. Journal of Medicinal Chemistry, 64 (7) acs.jmedchem.0c01882, 3658-3676. doi: 10.1021/acs.jmedchem.0c01882

Epidemiology of respiratory syncytial virus in a community birth cohort of infants in the first 2 years of life

Takashima, Mari D., Grimwood, Keith, Sly, Peter D., Lambert, Stephen B., Chappell, Keith J., Watterson, Daniel and Ware, Robert S. (2021). Epidemiology of respiratory syncytial virus in a community birth cohort of infants in the first 2 years of life. European Journal of Pediatrics, 180 (7), 2125-2135. doi: 10.1007/s00431-021-03998-0

An optimized high-throughput immuno-plaque assay for SARS-CoV-2

Amarilla, Alberto A., Modhiran, Naphak, Setoh, Yin Xiang, Peng, Nias Y. G., Sng, Julian D. J., Liang, Benjamin, McMillan, Christopher L. D., Freney, Morgan E, Cheung, Stacey T. M., Chappell, Keith J., Khromykh, Alexander A., Young, Paul R. and Watterson, Daniel (2021). An optimized high-throughput immuno-plaque assay for SARS-CoV-2. Frontiers in Microbiology, 12 625136, 625136. doi: 10.3389/fmicb.2021.625136

Adjuvant selection for influenza and RSV prefusion subunit vaccines

Isaacs, Ariel, Li, Zheyi, Cheung, Stacey T. M., Wijesundara, Danushka K., McMillan, Christopher L. D., Modhiran, Naphak, Young, Paul R., Ranasinghe, Charani, Watterson, Daniel and Chappell, Keith J. (2021). Adjuvant selection for influenza and RSV prefusion subunit vaccines. Vaccines, 9 (2) 71, 1-14. doi: 10.3390/vaccines9020071

A broadly protective antibody that targets the flavivirus NS1 protein

Modhiran, Naphak, Song, Hao, Liu, Lidong, Bletchly, Cheryl, Brillault, Lou, Amarilla, Alberto A., Xu, Xiaoying, Qi, Jianxun, Chai, Yan, Cheung, Stacey T. M., Traves, Renee, Setoh, Yin Xiang, Bibby, Summa, Scott, Connor A. P., Freney, Morgan E., Newton, Natalee D., Khromykh, Alexander A., Chappell, Keith J., Muller, David A., Stacey, Katryn J., Landsberg, Michael J., Shi, Yi, Gao, George F., Young, Paul R. and Watterson, Daniel (2021). A broadly protective antibody that targets the flavivirus NS1 protein. Science, 371 (6525), 190-194. doi: 10.1126/science.abb9425

The next generation of influenza vaccines: towards a universal solution

McMillan, Christopher L. D., Young, Paul R., Watterson, Daniel and Chappell, Keith J. (2021). The next generation of influenza vaccines: towards a universal solution. Vaccines, 9 (1) 26, 1-20. doi: 10.3390/vaccines9010026

Rapid response subunit vaccine design in the absence of structural information

Wijesundara, Danushka K., Avumegah, Michael S., Lackenby, Julia, Modhiran, Naphak, Isaacs, Ariel, Young, Paul R., Watterson, Daniel and Chappell, Keith J. (2020). Rapid response subunit vaccine design in the absence of structural information. Frontiers in Immunology, 11 592370, 592370. doi: 10.3389/fimmu.2020.592370

Micro-fusion inhibition tests: quantifying antibody neutralization of virus-mediated cell–cell fusion

Thakur, Nazia, Conceicao, Carina, Isaacs, Ariel, Human, Stacey, Modhiran, Naphak, McLean, Rebecca K., Pedrera, Miriam, Tan, Tiong Kit, Rijal, Pramila, Townsend, Alain, Taylor, Geraldine, Young, Paul R., Watterson, Daniel, Chappell, Keith J., Graham, Simon P. and Bailey, Dalan (2020). Micro-fusion inhibition tests: quantifying antibody neutralization of virus-mediated cell–cell fusion. Journal of General Virology, 102 (1) 001506. doi: 10.1099/jgv.0.001506

Genetic, morphological and antigenic relationships between mesonivirus isolates from Australian mosquitoes and evidence for their horizontal transmission

Newton, Natalee D., Colmant, Agathe M. G., O’Brien, Caitlin A., Ledger, Emma, Paramitha, Devina, Bielefeldt-Ohmann, Helle, Watterson, Daniel, McLean, Breeanna J., Hall-Mendelin, Sonja, Warrilow, David, van den Hurk, Andrew F., Liu, Wenjun, Hoare, Christina, Kizu, Joanne R., Gauci, Penelope J., Haniotis, John, Doggett, Stephen L., Shaban, Babak, Johansen, Cheryl A., Hall, Roy A. and Hobson-Peters, Jody (2020). Genetic, morphological and antigenic relationships between mesonivirus isolates from Australian mosquitoes and evidence for their horizontal transmission. Viruses, 12 (10) 1159, 1159. doi: 10.3390/v12101159

A unique relative of Rotifer birnavirus Isolated from Australian mosquitoes

O’Brien, Caitlin A., Pegg, Cassandra L., Nouwens, Amanda S., Bielefeldt-Ohmann, Helle, Huang, Bixing, Warrilow, David, Harrison, Jessica J., Haniotis, John, Schulz, Benjamin L., Paramitha, Devina, Colmant, Agathe M. G., Newton, Natalee D., Doggett, Stephen L., Watterson, Daniel, Hobson-Peters, Jody and Hall, Roy A. (2020). A unique relative of Rotifer birnavirus Isolated from Australian mosquitoes. Viruses, 12 (9) 1056, 1056. doi: 10.3390/v12091056

Bovine herpesvirus-4-vectored delivery of nipah virus glycoproteins enhances T cell immunogenicity in pigs

Pedrera, Miriam, Macchi, Francesca, McLean, Rebecca K., Franceschi, Valentina, Thakur, Nazia, Russo, Luca, Medfai, Lobna, Todd, Shawn, Tchilian, Elma Z., Audonnet, Jean-Christophe, Chappell, Keith, Isaacs, Ariel, Watterson, Daniel, Young, Paul R., Marsh, Glenn A., Bailey, Dalan, Graham, Simon P. and Donofrio, Gaetano (2020). Bovine herpesvirus-4-vectored delivery of nipah virus glycoproteins enhances T cell immunogenicity in pigs. Vaccines, 8 (1) 115, 115. doi: 10.3390/vaccines8010115

Flow-cytometry detection of fluorescent magnetic nanoparticle clusters increases sensitivity of dengue immunoassay

Sanjaya, K.C., Ranzoni, Andrea, Hung, Jacky, Blaskovich, Mark A.T., Watterson, Daniel, Young, Paul R. and Cooper, Matthew A. (2020). Flow-cytometry detection of fluorescent magnetic nanoparticle clusters increases sensitivity of dengue immunoassay. Analytica Chimica Acta, 1107, 85-91. doi: 10.1016/j.aca.2020.02.007

Novel monoclonal antibodies against Australian strains of negeviruses and insights into virus structure, replication and host -restriction

Colmant, Agathe M. G., O'Brien, Caitlin A., Newton, Natalee D., Watterson, Daniel, Hardy, Joshua, Coulibaly, Fasséli, Bielefeldt-Ohmann, Helle, Warrilow, David, Huang, Bixing, Paramitha, Devina, Harrison, Jessica J., Hall, Roy A. and Hobson-Peters, Jody (2020). Novel monoclonal antibodies against Australian strains of negeviruses and insights into virus structure, replication and host -restriction. Journal of General Virology, 101 (4), 440-452. doi: 10.1099/jgv.0.001388

A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus

Hobson-Peters, Jody, Harrison, Jessica J., Watterson, Daniel, Hazlewood, Jessamine E., Vet, Laura J., Newton, Natalee D., Warrilow, David, Colmant, Agathe M. G., Taylor, Carmel, Huang, Bixing, Piyasena, Thisun B. H., Chow, Weng Kong, Setoh, Yin Xiang, Tang, Bing, Nakayama, Eri, Yan, Kexin, Amarilla, Alberto A., Wheatley, Sarah, Moore, Peter R., Finger, Mitchell, Kurucz, Nina, Modhiran, Naphak, Young, Paul R., Khromykh, Alexander A., Bielefeldt-Ohmann, Helle, Suhrbier, Andreas and Hall, Roy A. (2019). A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus. Science Translational Medicine, 11 (522) eaax7888, 1-15. doi: 10.1126/scitranslmed.aax7888

Efficient delivery of dengue virus subunit vaccines to the skin by microprojection arrays

Muller, David A., Depelsenaire, Alexandra C. I., Shannon, Ashleigh E., Watterson, Daniel, Corrie, Simon R., Owens, Nick S., Agyei-Yeboah, Christiana, Cheung, Stacey T. M., Zhang, Jin, Fernando, Germain J. P., Kendall, Mark A. F. and Young, Paul R. (2019). Efficient delivery of dengue virus subunit vaccines to the skin by microprojection arrays. Vaccines, 7 (4) 189, 189. doi: 10.3390/vaccines7040189

Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon

Tan, Yuen P., Xue, Yongbo, Savchenko, Andrei I., Houston, Sevan D., Modhiran, Naphak, McMillan, Christopher L. D., Boyle, Glen M., Bernhardt, Paul V., Young, Paul R., Watterson, Daniel and Williams, Craig M. (2019). Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon. Journal of Natural Products, 82 (10) acs.jnatprod.9b00522, 2828-2834. doi: 10.1021/acs.jnatprod.9b00522

Dual targeting of dengue virus virions and NS1 protein with the heparan sulfate mimic PG545

Modhiran, Naphak, Gandhi, Neha S., Wimmer, Norbert, Cheung, Stacey, Stacey, Katryn, Young, Paul R., Ferro, Vito and Watterson, Daniel (2019). Dual targeting of dengue virus virions and NS1 protein with the heparan sulfate mimic PG545. Antiviral Research, 168, 121-127. doi: 10.1016/j.antiviral.2019.05.004

Determinants of Zika virus host tropism uncovered by deep mutational scanning

Setoh, Yin Xiang, Amarilla, Alberto A., Peng, Nias Y. G., Griffiths, Rebecca E., Carrera, Julio, Freney, Morgan E., Nakayama, Eri, Ogawa, Shinya, Watterson, Daniel, Modhiran, Naphak, Nanyonga, Faith Elizabeth, Torres, Francisco J., Slonchak, Andrii, Periasamy, Parthiban, Prow, Natalie A., Tang, Bing, Harrison, Jessica, Hobson-Peters, Jody, Cuddihy, Thom, Cooper-White, Justin, Hall, Roy A., Young, Paul R., Mackenzie, Jason M., Wolvetang, Ernst, Bloom, Jesse D., Suhrbier, Andreas and Khromykh, Alexander A. (2019). Determinants of Zika virus host tropism uncovered by deep mutational scanning. Nature Microbiology, 4 (5), 876-887. doi: 10.1038/s41564-019-0399-4

Stachyonic acid: a dengue virus inhibitor from Basilicum polystachyon

Tan, Yuen P., Houston, Sevan D., Modhiran, Naphak, Savchenko, Andrei I., Boyle, Glen M., Young, Paul R., Watterson, Daniel and Williams, Craig M. (2019). Stachyonic acid: a dengue virus inhibitor from Basilicum polystachyon. Chemistry – A European Journal, 25 (22) chem.201900591, 5664-5667. doi: 10.1002/chem.201900591

Suppression of the pelo protein by Wolbachia and its effect on dengue virus in Aedes aegypti

Asad, Sultan, Hussain, Mazhar, Hugo, Leon, Osei-Amo, Solomon, Zhang, Guangmei, Watterson, Daniel and Asgari, Sassan (2018). Suppression of the pelo protein by Wolbachia and its effect on dengue virus in Aedes aegypti. PLoS Neglected Tropical Diseases, 12 (4) e0006405, e0006405. doi: 10.1371/journal.pntd.0006405

New genotypes of Liao ning virus (LNV) in Australia exhibit an insect-specific phenotype

Prow, Natalie A., Mah, Marcus G., Deerain, Joshua M., Warrilow, David, Colmant, Agathe M. G., O'Brien, Caitlin A., Harrison, Jessica J., McLean, Breeanna J., Hewlett, Elise K., Piyasena, Thisun B. H., Hall-Mendelin, Sonja, van den Hurk, Andrew F., Watterson, Daniel, Huang, Bixing, Schulz, Benjamin L., Webb, Cameron E., Johansen, Cheryl A., Chow, Weng K., Hobson-Peters, Jody, Cazier, Chris, Coffey, Lark L., Faddy, Helen M., Suhrbier, Andreas, Bielefeldt-Ohmann, Helle and Hall, Roy A. (2018). New genotypes of Liao ning virus (LNV) in Australia exhibit an insect-specific phenotype. The Journal of General Virology, 99 (4), 596-609. doi: 10.1099/jgv.0.001038

Pathogenesis, humoral immune responses and transmission between co-housed animals in a ferret model of human RSV infection

Chan, Kok Fei, Carolan, Louise A., Druce, Julian, Chappell, Keith, Watterson, Daniel, Young, Paul, Korenkov, Daniil, Subbarao, Kanta, Barr, Ian G., Laurie, Karen L. and Reading, Patrick C. (2018). Pathogenesis, humoral immune responses and transmission between co-housed animals in a ferret model of human RSV infection. Journal of Virology, 92 (4) e01322-17, 1-17. doi: 10.1128/JVI.01322-17

The heptad repeat C domain of the respiratory syncytial virus fusion protein plays a key role in membrane fusion

Bermingham, Imogen M., Chappell, Keith J., Watterson, Daniel and Young, Paul R. (2018). The heptad repeat C domain of the respiratory syncytial virus fusion protein plays a key role in membrane fusion. Journal of Virology, 92 (4) e01323-17, 1-14. doi: 10.1128/JVI.01323-17

Structural and functional characterization of a cross-reactive dengue virus neutralizing antibody that recognizes a cryptic epitope

Li, Jie, Watterson, Daniel, Chang, Chiung-Wen, Che, Xiao-Yan, Li, Xiao-Quan, Ericsson, Daniel J., Qiu, Li-Wen, Cai, Jian-Piao, Chen, Jing, Fry, Scott R., Cheung, Stacey T. M., Cooper, Matthew A., Young, Paul R. and Kobe, Bostjan (2018). Structural and functional characterization of a cross-reactive dengue virus neutralizing antibody that recognizes a cryptic epitope. Structure, 26 (1), 51-59. doi: 10.1016/j.str.2017.11.017

Induction of high titred, non-neutralising antibodies by self-adjuvanting peptide epitopes derived from the respiratory syncytial virus fusion protein

Jaberolansar, Noushin, Chappell, Keith J., Watterson, Daniel, Bermingham, Imogen M., Toth, Istvan, Young, Paul R. and Skwarczynski, Mariusz (2017). Induction of high titred, non-neutralising antibodies by self-adjuvanting peptide epitopes derived from the respiratory syncytial virus fusion protein. Scientific Reports, 7 (1) 11130, 11130. doi: 10.1038/s41598-017-10415-w

Reduction of Zika virus infectivity in platelet concentrates after treatment with ultraviolet C light and in plasma after treatment with methylene blue and visible light

Fryk, Jesse J., Marks, Denese C., Hobson-Peters, Jody, Watterson, Daniel, Hall, Roy A., Young, Paul R., Reichenberg, Stefan, Tolksdorf, Frank, Sumian, Chryslain, Gravemann, Ute, Seltsam, Axel and Faddy, Helen M. (2017). Reduction of Zika virus infectivity in platelet concentrates after treatment with ultraviolet C light and in plasma after treatment with methylene blue and visible light. Transfusion, 57 (11), 2677-2682. doi: 10.1111/trf.14256

A new clade of insect-specific flaviviruses from Australian Anopheles mosquitoes displays species-specific host-restriction

Colmant, Agathe M. G., Hobson-Peters, Jody, Bielefeldt-Ohmann, Helle, van den Hurk, Andrew F., Hall-Mendelin, Sonja, Chow, Weng Kong, Johansen, Cheryl A., Fros, Jelke, Simmonds, Peter, Watterson, Daniel, Cazier, Chris, Etebari, Kayvan, Asgari, Sassan, Schulz, Benjamin L., Beebe, Nigel, Vet, Laura J., Piyasena, Thisun B. H., Nguyen, Hong-Duyen, Barnard, Ross T. and Hall, Roy A. (2017). A new clade of insect-specific flaviviruses from Australian Anopheles mosquitoes displays species-specific host-restriction. mSphere, 2 (4) e00262-17, 1-19. doi: 10.1128/mSphere.00262-17

Isolation of serotype-specific antibodies against dengue virus non-structural protein 1 using phage display and application in a multiplexed serotyping assay

Lebani, Kebaneilwe, Jones, Martina L., Watterson, Daniel, Ranzoni, Andrea, Traves, Renee J., Young, Paul R. and Mahler, Stephen M. (2017). Isolation of serotype-specific antibodies against dengue virus non-structural protein 1 using phage display and application in a multiplexed serotyping assay. PLoS One, 12 (7) e0180669, e0180669. doi: 10.1371/journal.pone.0180669

Computational identification of antibody epitopes on the dengue virus NS1 protein

Jones, Martina L., Legge, Fiona S., Lebani, Kebaneilwe, Mahler, Stephen M., Young, Paul R., Watterson, Daniel, Treutlein, Herbert R. and Zeng, Jun (2017). Computational identification of antibody epitopes on the dengue virus NS1 protein. Molecules, 22 (4) 607, 607. doi: 10.3390/molecules22040607

Discovery and characterisation of castlerea virus, a new species of Negevirus isolated in Australia

O'Brien, Caitlin A., McLean, Breeanna J., Colmant, Agathe M. G., Harrison, Jessica J., Hall-Mendelin, Sonja, van den Hurk, Andrew F., Johansen, Cheryl A., Watterson, Daniel, Bielefeldt-Ohmann, Helle, Newton, Natalee D., Schulz, Benjamin L., Hall, Roy A. and Hobson-Peters, Jody (2017). Discovery and characterisation of castlerea virus, a new species of Negevirus isolated in Australia. Evolutionary Bioinformatics, 13, 1176934317691269. doi: 10.1177/1176934317691269

Dengue virus NS1 protein activates immune cells via TLR4 but not TLR2 or TLR6

Modhiran, Naphak, Watterson, Daniel, Blumenthal, Antje, Baxter, Alan G., Young, Paul R. and Stacey, Katryn J. (2017). Dengue virus NS1 protein activates immune cells via TLR4 but not TLR2 or TLR6. Immunology and Cell Biology, 95 (5), 491-495. doi: 10.1038/icb.2017.5

Successful post-exposure prophylaxis of Ebola infected non-human primates using Ebola glycoprotein-specific equine IgG

Pyankov, Oleg V., Setoh, Yin Xiang, Bodnev, Sergey A., Edmonds, Judith H., Pyankova, Olga G., Pyankov, Stepan A., Pali, Gabor, Belford, Shane, Lu, Louis, La, Mylinh, Lovrecz, George, Volchkova, Valentina A., Chappell, Keith J., Watterson, Daniel, Marsh, Glenn, Young, Paul R., Agafonov, Alexander A., Farmer, Jillann F., Volchkov, Victor E., Suhrbier, Andreas and Khromykh, Alexander A. (2017). Successful post-exposure prophylaxis of Ebola infected non-human primates using Ebola glycoprotein-specific equine IgG. Scientific Reports, 7 (1) 41537, 41537. doi: 10.1038/srep41537

Fighting Ebola: a window for vaccine re-evaluation?

Chappell, Keith J. and Watterson, Daniel (2017). Fighting Ebola: a window for vaccine re-evaluation?. PLoS Pathogens, 13 (1) e1006037, e1006037. doi: 10.1371/journal.ppat.1006037

Product release is rate-limiting for catalytic processing by the Dengue virus protease

Shannon, A. E., Pedroso, M. M., Chappell, K. J., Watterson, D., Liebscher, S., Kok, W. M., Fairlie, D. P., Schenk, G. and Young, P. R. (2016). Product release is rate-limiting for catalytic processing by the Dengue virus protease. Scientific Reports, 6 (1) 37539, 37539. doi: 10.1038/srep37539

Phylogenetic diversity of koala retrovirus within a wild koala population

Chappell, K. J., Brealey, J. C., Amarilla, A. A., Watterson, D., Hulse, L., Palmieri, C., Johnston, S. D., Holmes, E. C., Meers, J. and Young, P. (2016). Phylogenetic diversity of koala retrovirus within a wild koala population. Journal of Virology, 91 (3) e01820-16, 363-374. doi: 10.1128/JVI.01820-16

Viral pathogen vaccines

Young, Paul, Chappell, Keith and Watterson, Dan (2016). Viral pathogen vaccines. Australasian Biotechnology, 26 (3), 35-35.

Dengue and chikungunya viruses in plasma are effectively inactivated after treatment with methylene blue and visible light

Fryk, Jesse J., Marks, Denese C., Hobson-Peters, Jody, Prow, Natalie A., Watterson, Daniel, Hall, Roy A., Young, Paul R., Reichenberg, Stefan, Sumian, Chryslain and Faddy, Helen M. (2016). Dengue and chikungunya viruses in plasma are effectively inactivated after treatment with methylene blue and visible light. Transfusion, 56 (9), 2278-2285. doi: 10.1111/trf.13729

Riboflavin and ultraviolet light: impact on dengue virus infectivity

Faddy, H. M., Fryk, J. J., Watterson, D., Young, P. R., Modhiran, N., Muller, D. A., Keil, S. D., Goodrich, R. P. and Marks, D. C. (2016). Riboflavin and ultraviolet light: impact on dengue virus infectivity. Vox Sanguinis, 111 (3), 235-241. doi: 10.1111/vox.12414

Inactivation of dengue, chikungunya, and Ross River viruses in platelet concentrates after treatment with ultraviolet C light

Faddy, Helen M., Fryk, Jesse J., Prow, Natalie A., Watterson, Daniel, Young, Paul R., Hall, Roy A., Tolksdorf, Frank, Sumian, Chryslain, Gravemann, Ute, Seltsam, Axel and Marks, Denese C. (2016). Inactivation of dengue, chikungunya, and Ross River viruses in platelet concentrates after treatment with ultraviolet C light. Transfusion, 56 (6pt2), 1548-1555. doi: 10.1111/trf.13519

The many faces of the flavivirus NS1 protein offer a multitude of options for inhibitor design

Watterson, Daniel, Modhiran, Naphak and Young, Paul R. (2016). The many faces of the flavivirus NS1 protein offer a multitude of options for inhibitor design. Antiviral Research, 130, 7-18. doi: 10.1016/j.antiviral.2016.02.014

A new Orbivirus isolated from mosquitoes in north-western Australia shows antigenic and genetic similarity to Corriparta virus but does not replicate in vertebrate cells

Harrison, Jessica J., Warrilow, David, McLean, Breeanna J., Watterson, Daniel, O'Brien, Caitlin A., Colmant, Agathe M.G., Johansen, Cheryl A., Barnard, Ross T., Hall-Mendelin, Sonja, Davis, Steven S., Hall, Roy A. and Hobson-Peters, Jody (2016). A new Orbivirus isolated from mosquitoes in north-western Australia shows antigenic and genetic similarity to Corriparta virus but does not replicate in vertebrate cells. Viruses, 8 (5) 141, e141.1-e141.15. doi: 10.3390/v8050141

Genetic characterization of archived bunyaviruses and their potential for emergence in Australia

Huang, Bixing, Firth, Cadhla, Watterson, Daniel, Allcock, Richard, Colmant, Agathe M. G., Hobson-Peters, Jody, Kirkland, Peter, Hewitson, Glen, McMahon, Jamie, Hall-Mendelin, Sonja, van den Hurk, Andrew F. and Warrilow, David (2016). Genetic characterization of archived bunyaviruses and their potential for emergence in Australia. Emerging Infectious Diseases, 22 (5), 833-840. doi: 10.3201/eid2205.151566

A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedance

Watterson, Daniel, Robinson, Jodie, Chappell, Keith J., Butler, Mark S., Edwards, David J., Fry, Scott R., Bermingham, Imogen M., Cooper, Matthew A. and Young, Paul R. (2016). A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedance. Scientific Reports, 6 (22791) 22791, 1-9. doi: 10.1038/srep22791

Discovery and characterisation of a new insect-specific bunyavirus from Culex mosquitoes captured in northern Australia

Hobson-Peters, Jody, Warrilow, David, McLean, Breeanna J., Watterson, Daniel, Colmant, Agathe M.G., van den Hurk, Andrew F., Hall-Mendelin, Sonja, Hastie, Marcus L., Gorman, Jeffrey J., Harrison, Jessica J., Prow, Natalie A., Barnard, Ross T., Allcock, Richard, Johansen, Cheryl A. and Hall, Roy A. (2016). Discovery and characterisation of a new insect-specific bunyavirus from Culex mosquitoes captured in northern Australia. Virology, 489, 269-281. doi: 10.1016/j.virol.2015.11.003

Response to comment on "Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity" and "Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination"

Stacey, Katryn J., Watterson, Daniel, Modhiran, Naphak and Young, Paul R. (2015). Response to comment on "Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity" and "Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination". Science Translational Medicine, 7 (318) 318lr4, 318lr4-318lr4. doi: 10.1126/scitranslmed.aad8657

Quantification of NS1 dengue biomarker in serum via optomagnetic nanocluster detection.

Antunes, Paula, Watterson, Daniel, Parmvi, Mattias, Burger, Robert, Boisen, Anja, Young, Paul, Cooper, Matthew A., Hansen, Mikkel F., Ranzoni, Andrea and Donolato, Marco (2015). Quantification of NS1 dengue biomarker in serum via optomagnetic nanocluster detection.. Scientific Reports, 5 (16145) 16145, 1-10. doi: 10.1038/srep16145

A novel insect-specific flavivirus replicates only in Aedes-derived cells and persists at high prevalence in wild Aedes vigilax populations in Sydney, Australia

McLean, Breeanna J., Hobson-Peters, Jody, Webb, Cameron E., Watterson, Daniel, Prow, Natalie A., Nguyen, Hong Duyen, Hall-Mendelin, Sonja, Warrilow, David, Johansen, Cheryl A., Jansen, Cassie C., van den Hurk, Andrew F., Beebe, Nigel W., Schnettler, Esther, Barnard, Ross T. and Hall, Roy A. (2015). A novel insect-specific flavivirus replicates only in Aedes-derived cells and persists at high prevalence in wild Aedes vigilax populations in Sydney, Australia. Virology, 486, 272-283. doi: 10.1016/j.virol.2015.07.021

Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity

Modhiran, Naphak, Watterson, Daniel, Muller, David A., Panetta, Adele K., Sester, David P., Liu, Lidong, Hume, David A., Stacey, Katryn J. and Young, Paul R. (2015). Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity. Science Translational Medicine, 7 (304) 304ra142, 1-10. doi: 10.1126/scitranslmed.aaa3863

Viral RNA intermediates as targets for detection and discovery of novel and emerging mosquito-borne viruses

O'Brien, Caitlin A., Hobson-Peters, Jody, Yam, Alice Wei Yee, Colmant, Agathe M. G., McLean, Breeanna J., Prow, Natalie A., Watterson, Daniel, Hall-Mendelin, Sonja, Warrilow, David, Ng, Mah-Lee, Khromykh, Alexander A. and Hall, Roy A. (2015). Viral RNA intermediates as targets for detection and discovery of novel and emerging mosquito-borne viruses. PLoS Neglected Tropical Diseases, 9 (3) e0003629, 1-27. doi: 10.1371/journal.pntd.0003629

Resistance of Black-lip learl oyster, Pinctada margaritifera, to infection by Ostreid herpes virus 1(mu)var under experimental challenge may be mediated by humoral antiviral activity

Tan, Terence L. S., Paul-Pont, Ika, Evans, Olivia M., Watterson, Daniel, Young, Paul, Whittington, Richard, Fougerouse, Angelique, Bichet, Hervé, Barnes, Andrew C. and Dang, Cécile (2015). Resistance of Black-lip learl oyster, Pinctada margaritifera, to infection by Ostreid herpes virus 1(mu)var under experimental challenge may be mediated by humoral antiviral activity. Fish and Shellfish Immunology, 44 (1), 232-240. doi: 10.1016/j.fsi.2015.02.026

Evaluation of direct versus multi-layer passivation and capture chemistries for nanoparticle-based biosensor applications

Sanjaya, K. C., Ranzoni, Andrea, Watterson, Daniel, Young, Paul and Cooper, Matthew A. (2014). Evaluation of direct versus multi-layer passivation and capture chemistries for nanoparticle-based biosensor applications. Biosensors and Bioelectronics, 67, 769-774. doi: 10.1016/j.bios.2014.09.048

A new species of mesonivirus from the Northern Territory, Australia

Warrilow, David, Watterson, Daniel, Hall, Roy A., Davis, Steven S., Weir, Richard, Kurucz, Nina, Whelan, Peter, Allcock, Richard, Hall-Mendelin, Sonja, O'Brien, Caitlin A. and Hobson-Peters, Jody (2014). A new species of mesonivirus from the Northern Territory, Australia. PLoS ONE, 9 (3) e91103, e91103.1-e91103.9. doi: 10.1371/journal.pone.0091103

Residues in domain III of the dengue virus envelope glycoprotein involved in cell-surface glycosaminoglycan binding

Watterson, Daniel, Kobe, Bostjan and Young, Paul R. (2012). Residues in domain III of the dengue virus envelope glycoprotein involved in cell-surface glycosaminoglycan binding. Journal of General Virology, 93 (1), 72-82. doi: 10.1099/vir.0.037317-0

Democratising large scale instrument-based science through e-Infrastructure

Abramson, David, Barkauskas, Deborah S., Carroll, Jake, Condon, Nicholas D, Modhiran, Naphak, Nguyen, Hoang, Springfield, James, Watterson, Daniel and Jin, Chao (2022). Democratising large scale instrument-based science through e-Infrastructure. IEEE 18th International Conference on E-Science (E-Science), Salt Lake City, UT USA, 10-14 October 2022. New York, NY USA: Institute of Electrical and Electronics Engineers. doi: 10.1109/escience55777.2022.00033

Targeted delivery of candidate dengue virus subunit vaccine to the skin using the Nanopatch™

Muller, D. A., Depelsenaire, A. C. I., Watterson, D., Zhang, J., Yukiko, S. R., Young, P. R. and Kendall, M. A. F. (2014). Targeted delivery of candidate dengue virus subunit vaccine to the skin using the Nanopatch™. Vaccine Technology V, Playa del Carmen, Mexico, 8-13 June 2014.

Nanopatch delivery of a tetravalent recombinant subunit dengue vaccine

Depelsenaire, Alexandra C. I., Watterson, Daniel, Zhang, Jin, Yukiko, Sally, Young, Paul R., Kendall, Mark A. F. and Muller, David A. (2013). Nanopatch delivery of a tetravalent recombinant subunit dengue vaccine. Australasian Virology Society Meeting 2013, Queenstown, New Zealand, 8-11 December 2013.

The effect of pathogen reduction technology (mirasol) on the infectivity of Denuge viruses

Faddy, H., Fryk, J., Young, P., Watterson, D., Goodrich, R. and Marks, D. (2012). The effect of pathogen reduction technology (mirasol) on the infectivity of Denuge viruses. 32nd International Congress of the International Society of Blood Transfusion in joint cooperation with the 10th Congress of AMMTAC, Cancun, Mexico, 7-12 July 2012. Oxford, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/j.1423-0410.2012.01615_2.x

Sneaking up on West Nile Virus NS2B/NS3 protease subcellular activity utilising dye-quenched substrates

Liebscher, Susan, Chappell, K. J., Stoermer, Martin J., Watterson, Daniel, Webb, Richard I., Khromykh, Alexander A., Fairlie, David P. and Young, Paul R. (2010). Sneaking up on West Nile Virus NS2B/NS3 protease subcellular activity utilising dye-quenched substrates. PlusStrand 2010: The Ninth International Symposium on Positive-Strand RNA Viruses, Atlanta, GA, U.S.A., 17-21 May 2010.

Development of a novel dengue virus binding assay using a recombinant sub-domain of E in a live cell LISA format

Watterson, D. and Young, P. R. (2006). Development of a novel dengue virus binding assay using a recombinant sub-domain of E in a live cell LISA format. Australian Society for Microbiology Annual Scientific Meeting, Gold Coast, Qld, 2-6 July, 2006.

Development of a novel dengue virus binding assay using a recombinant sub-domain of E in a live cell ELISA format

Watterson, D. and Young, P. R. (2005). Development of a novel dengue virus binding assay using a recombinant sub-domain of E in a live cell ELISA format. 3rd Australian Virology Group Meeting, Phillip Island, 9-12 December, 2005.

Examining the dual role of dengue virus E domain III in receptor binding and membrane fusion

Watterson, Daniel (2012). Examining the dual role of dengue virus E domain III in receptor binding and membrane fusion. PhD Thesis, School of Chemistry and Molecular Biosciences, The University of Queensland.