Associate Professor Dominic Ng

Associate Professor

School of Biomedical Sciences
Faculty of Medicine
d.ng1@uq.edu.au
+61 7 336 53077

Overview

Dr Dominic Ng graduated with a BSc (Hons) and gained his PhD from the University of Western Australia. His doctoral studies, conducted in the laboratory of Assoc. Prof. Marie Bogoyevitch, were focused on cardiomyocyte signalling mechanisms regulating pathological tissue growth (ie cardiac hypertrophy). He continued his research training in Singapore as a post-doctoral research fellow based at the Institute of Molecular and Cell Biology, the flagship institute of Singapore’s science agency (A*STAR) located at the world renowned Biopolis research precinct. During this time, his research interests turned to the complex regulation of the cytoskeleton and their functions in development and disease.

He returned to the Australian medical research community on an NHMRC Peter Doherty Fellowship (2006-2010) followed by a Faculty Trust Roper Fellowship (2011-2012). In this time, Dominic established an independent research program focused on complex signalling regulation of microtubule organization. In 2013, Dominic was appointed as a Senior Research Fellow, supported by an ARC Future Fellowship (2013-2016) at the Department of Biochemistry within the Bio21 Institute, University of Melbourne. In 2015, Dominic relocated his research group to the School of Biomedical Science, University of Queensland and is currently appointed as an ARC Future Fellow and Senior Lecturer.

Research Interests

  • Cell Signalling
    Protein phosphorylation, protein interactions, kinases, STAT transcription factors, microtubule-associated proteins.
  • Molecular Cardiology
    Cardiomyocyte growth, cardiac hypertrophy, cardiac injury, cardioprotection
  • Neural Development
    Neural stem cells, microcephaly genes, neural migration, neural proliferation, neuronal cell death

Qualifications

  • Doctor of Philosophy, University of Western Australia
  • Bachelor of Science, University of Western Australia

Publications

  • Yan, Yu, Wang, Dean, Xin, Ruiqi, Soriano, Raine A., Ng, Dominic C. M., Wang, Wei and Ping, Peipei (2023). Protocol for the prediction, interpretation, and mutation evaluation of post-translational modification using MIND-S. Star Protocols, 4 (4) ARTN 102682, 102682. doi: 10.1016/j.xpro.2023.102682

  • Ding, Qiao, Kesavan, Kaamini, Lee, Kah Meng, Wimberger, Elyse, Robertson, Thomas, Gill, Melinder, Power, Dominique, Chang, Jeryn, Fard, Atefeh T., Mar, Jessica C., Henderson, Robert D., Heggie, Susan, McCombe, Pamela A., Jeffree, Rosalind L., Colditz, Michael J., Hilliard, Massimo A., Ng, Dominic C. H., Steyn, Frederik J., Phillips, William D., Wolvetang, Ernst J., Ngo, Shyuan T. and Noakes, Peter G. (2022). Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron Disease. Acta Neuropathologica Communications, 10 (1) 61, 61. doi: 10.1186/s40478-022-01360-5

  • Rashidieh, Behnam, Shohayeb, Belal, Bain, Amanda Louise, Fortuna, Patrick R. J., Sinha, Debottam, Burgess, Andrew, Mills, Richard, Adams, Rachael C., Lopez, J. Alejandro, Blumbergs, Peter, Finnie, John, Kalimutho, Murugan, Piper, Michael, Hudson, James Edward, Ng, Dominic C. H. and Khanna, Kum Kum (2021). Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis. PLoS Genetics, 17 (10) e1009334, e1009334. doi: 10.1371/journal.pgen.1009334

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Grants

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Supervision

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Publications

Book Chapter

  • Ng, Dominic Chi Hiung and Byrne, Frances (2012). Stathmin and cancer. Cytoskeleton and Human Disease. (pp. 259-284) edited by Maria Kavallaris. New York, NY USA: Humana Press. doi: 10.1007/978-1-61779-788-0_14

Journal Article

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor