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Professor David McIntyre

Emeritus Professor

Mater Research Institute-UQ
Faculty of Medicine
h.d.mcintyre@uq.edu.au

Overview

Professor David McIntyre trained in Endocrinology in Australia and Belgium. He works clinically as Director of Obstetric Medicine at Mater Health Services and is an Emeritus Professor in the Faculty of Medicine (Mater Research). David has published over 250 papers (>25000 citations), primarily in the field of medical complications of pregnancy, with a particular focus on diabetes and obesity. Recent research has examined the effects of diabetes, obesity and hypertension during pregnancy on the health of Mothers and Babies, during pregnancy and with long term follow up. David is a Past Chair of the Australasian Diabetes in Pregnancy Society and the International Association of Diabetes in Pregnancy Study Groups (IADPSG). In 2016, David became the first Australian trained clinician to receive the Norbert Freinkel Award for contributions to diabetes in pregnancy from the American Diabetes Association. In 2019 he was awarded the Jørgen Pedersen Lecture for diabetes in pregnancy by DPSG Europe and the Stream Lead Award Lecture for “Diabetes and Women” by the International Diabetes Federation.

Research Interests

  • DIabetes in pregnancy
  • Medical complications of pregnancy
  • Obesity in pregnancy
  • Intensive insulin therapy in Type 1 diabetes
  • Life course epidemiology of cardiometabolic disease

Research Impacts

Direct impact on clinical practice:

  • Testing for gestational diabetes mellitus (GDM). Professor McIntyre has been centrally involved in the development and dissemination of the IADPSG recommendations for diagnosis of GDM. This has included membership of the consensus conference, which developed the IADPSG recommendations, and of the writing group, which finalized the proposed criteria. On a national level, he was involved in representations to the college of Obstetrics and Gynecology, ADIPS and the Australian Diabetes Society (ADS) as well as within Queensland) and locally at the Mater Mothers Hospital. He chaired the GDM workgroup for the Statewide Clinical Diabetes Network and was lead author on local GDM guidelines. Internationally, he has been closely involved in similar processes as Chair of IADPSG and a member of the FIGO Pregnancy and Non Communicable Disease (NCD) committee.
  • Intensive diabetes management. Since 2004, he has been a founding member of the OzDAFNE collaboration, which introduced the Dose Adjustment for Normal Eating (DAFNE) system of education in intensive insulin therapy for Type 1 diabetes patients into clinical practice in Australia. This has become the mainstay of such treatment in Queensland and DAFNE courses are now offered in over 20 centres across Australia and New Zealand.

Clinical Practice Guidelines:

Professor McIntyre participated in the development of clinical practice guidelines for Obesity in pregnancy via the Statewide Maternity and Neonatal Network and served as Co-lead of the group which developed a guideline for GDM diagnosis and treatment published in 2015.

Investigator-initiated Clinical Trials:

  • He has been involved in the MiG trial of metformin in the management of gestational diabetes and I have started the first Australian site for the “MiTY” (Metformin in Type 2 diabetes) trial to further examine the use of this medication in pregnancy.
  • He was Chief Investigator B and lead at Mater Health Services for the “SPRING” (Supplementation with Probiotics in Gestation) trial recently reported its negative findings regarding the use of probiotics in GDM prevention.
  • He has initiated two RCTs dealing with lifestyle strategies in the prevention of progression to Type 2 diabetes following GDM.
  • He was CI on a further RCT “TRIM” (Trial of Weight Reduction in New Mums) dealing with optimal dietary follow up to reduce post-partum weight retention in obese pregnant women.

Public Health: Throughhis ole in the National Diabetes in Pregnancy Advisory Committee, he hascontributed to definition of priorities for the care of women with diabetes before, during and after pregnancy. Hiscontributions to GDM care also relate to Public Health as GDM is the commonest identifiable antecedent to overt Type 2 diabetes in parous women.

Qualifications

  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Doctoral Diploma of Medicine, The University of Queensland
  • Bachelor of Medicine and Surgery and Medical Science, The University of Queensland

Publications

  • Journal Article: Gestational diabetes mellitus

    McIntyre, H. David, Catalano, Patrick, Zhang, Cuilin, Desoye, Gernot, Mathiesen, Elisabeth R. and Damm, Peter (2019). Gestational diabetes mellitus. Nature Reviews Disease Primers, 5 (1) 47. doi: 10.1038/s41572-019-0098-8

  • Journal Article: Development of a risk engine relating maternal glycemia and body mass index to pregnancy outcomes

    McIntyre, H. David, Gibbons, Kristen S., Lowe, Julia and Oats, Jeremy J. N. (2018). Development of a risk engine relating maternal glycemia and body mass index to pregnancy outcomes. Diabetes Research and Clinical Practice, 139, 331-338. doi: 10.1016/j.diabres.2018.02.036

  • Journal Article: FIGO analysis of research priorities in hyperglycemia in pregnancy

    McIntyre, David, Desoye, Gernot, Dunne, Fidelma, Simeoni, Umberto, H A Visser, Gerard, Kapur, Anil and Hod, Moshe (2018). FIGO analysis of research priorities in hyperglycemia in pregnancy. Diabetes Research and Clinical Practice, 145, 5-14. doi: 10.1016/j.diabres.2018.03.026

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Grants

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Supervision

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Publications

Featured Publications

  • Gestational diabetes mellitus

    McIntyre, H. David, Catalano, Patrick, Zhang, Cuilin, Desoye, Gernot, Mathiesen, Elisabeth R. and Damm, Peter (2019). Gestational diabetes mellitus. Nature Reviews Disease Primers, 5 (1) 47. doi: 10.1038/s41572-019-0098-8

  • Development of a risk engine relating maternal glycemia and body mass index to pregnancy outcomes

    McIntyre, H. David, Gibbons, Kristen S., Lowe, Julia and Oats, Jeremy J. N. (2018). Development of a risk engine relating maternal glycemia and body mass index to pregnancy outcomes. Diabetes Research and Clinical Practice, 139, 331-338. doi: 10.1016/j.diabres.2018.02.036

  • FIGO analysis of research priorities in hyperglycemia in pregnancy

    McIntyre, David, Desoye, Gernot, Dunne, Fidelma, Simeoni, Umberto, H A Visser, Gerard, Kapur, Anil and Hod, Moshe (2018). FIGO analysis of research priorities in hyperglycemia in pregnancy. Diabetes Research and Clinical Practice, 145, 5-14. doi: 10.1016/j.diabres.2018.03.026

Book Chapter

  • Adrenal disease in pregnancy

    Lockett, Jack, Inder, Warrick, McIntyre, David H., Barrett, Helen L., Kumar, Sailesh and Clifton, Vicki Lee (2022). Adrenal disease in pregnancy. Hormones and pregnancy. (pp. 164-182) edited by Felice Petraglia, Mariarosaria Di Tommaso and Federico Mecacci. Cambridge, United Kingdom: Cambridge University Press. doi: 10.1017/9781009030830.015

  • Gestational Diabetes

    McIntyre, H. David and Oats, Jeremy J. N. (2022). Gestational Diabetes. Endocrinology and Diabetes: A Problem Oriented Approach: Second Edition. (pp. 315-324) Cham, Switzerland: Springer. doi: 10.1007/978-3-030-90684-9_29

  • Cost of pregnancy complications related to noncommunicable diseases and cost effectiveness of interventions to address them

    Kapur, Anil, Hyett, Jon and McIntyre, H. David (2020). Cost of pregnancy complications related to noncommunicable diseases and cost effectiveness of interventions to address them. New technologies and perinatal medicine: prediction and prevention of pregnancy complications. (pp. 60-72) edited by Moshe Hod, Vincenzo Berghella, Mary E. D'Alton, Gian Carlo Di Renzo, Eduard Gratacós and Vassilios Fanos. Boca Raton, FL, United States: CRC Press. doi: 10.1201/9781315201955-11

  • Obesity in pregnancy: epidemiology, mechanisms, nutritional and metabolic management

    McIntyre, H. David, Dekker, Marloes, Barrett, Helen L. and Callaway, Leonie K. (2020). Obesity in pregnancy: epidemiology, mechanisms, nutritional and metabolic management. Gestational Diabetes: A Decade after the HAPO Study. (pp. 21-34) edited by Annunziata Lapolla and Boyd E. Metzger. Basel, Switzerland: S. Karger. doi: 10.1159/000480163

  • Gestational diabetes mellitus, obesity, and pregnancy outcomes

    McIntyre, Harold David, Dekker-Nitert, Marloes, Barrett, Helen Lorraine Graham and Callaway, Leonie Kaye (2018). Gestational diabetes mellitus, obesity, and pregnancy outcomes. Textbook of Diabetes and Pregnancy. (pp. 246-252) Boca Raton, FL United States: CRC Press.

  • Biomarkers of metabolic and cardiovascular risk in gestational diabetes

    Nitert, Marloes Dekker, Callaway, Leonie K., McIntyre, H. David and Barrett, Helen L. (2018). Biomarkers of metabolic and cardiovascular risk in gestational diabetes. Nutrition and diet in maternal diabetes: an evidence-based approach. (pp. 147-159) edited by Rajkumar Rajendram, Victor R. Preedy and Vinood B. Patel. Cham, Switzerland: Springer Nature. doi: 10.1007/978-3-319-56440-1_13

  • Probiotics in the prevention of gestational diabetes mellitus (GDM)

    Gomez Arango, Luisa F., Barrett, Helen L., Callaway, Leonie K., McIntyre, H. David and Nitert, Marloes Dekker (2018). Probiotics in the prevention of gestational diabetes mellitus (GDM). Nutrition and diet in maternal diabetes: an evidence-based approach. (pp. 275-288) edited by Rajkumar Rajendram, Victor R. Preedy and Vinood B. Patel. Cham, Switzerland: Humana Press. doi: 10.1007/978-3-319-56440-1_22

  • Obesity and diabetes in pregnancy

    McIntyre, H. David, Nitert, Marloes Dekker, Barrett, Helen L. and Callaway, Leonie K. (2017). Obesity and diabetes in pregnancy. A practical manual of diabetes in pregnancy. (pp. 87-103) edited by David R. McCance, Michael Maresh and David A. Sacks. Chichester, UK: John Wiley & Sons. doi: 10.1002/9781119043805.ch7

  • Gestational diabetes

    McIntyre, H. David, Baskerville, Catherine and Oats, Jeremy J. N. (2014). Gestational diabetes. Endocrinology and diabetes: a problem-oriented approach. (pp. 361-373) edited by Francisco Bandeira, Hossein Gharib, Airton Golbert, Luiz Griz and Manuel Faria. New York, NY, United States: Springer New York. doi: 10.1007/978-1-4614-8684-8_28

  • Preconception care and barriers to addressing overweight and obesity: a focus on weight loss advice and weight loss strategies

    Dekker Nitert, M., Barrett, H. L., de Jersey, S., Matusiak, K., McIntyre, H. D. and Callaway, L. K. (2014). Preconception care and barriers to addressing overweight and obesity: a focus on weight loss advice and weight loss strategies. Handbook of diet and nutrition in the menstrual cycle, periconception and fertility. (pp. 327-342) edited by HollinsMartin, C, VanDenAkker, O, Martin, C and Preedy, VR. Wageningen, Netherlands: Wageningen Academic Publishers. doi: 10.3920/978-90-8686-767-7.020

  • Obesity in pregnancy: data from the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study

    McIntyre, Harold David, Lowe, Lynn P., Dyer, Alan R. and Metzger, Boyd E. (2012). Obesity in pregnancy: data from the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study. Maternal obesity and pregnancy. (pp. 271-281) edited by Per Glud Ovesen and Dorte Møller Jensen. Heidelberg, Germany: Springer. doi: 10.1007/978-3-642-25023-1_17

Journal Article

Conference Publication

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

Completed Supervision

This staff member is a UQ Expert for media in the following fields:

pregnancy, obesity, type 1 diabetes, gestational diabetes, diabetes

They are happy to lend their expertise to your articles or broadcasts and share their research discoveries and insights with the community via media channels.

For additional assistance with story ideas, general advice and information or help with seeking further experts, please email the UQ Media Team or telephone (07) 3365 1120.

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ResearcherID: F-1888-2010

ORCID: 0000-0001-8819-5794

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