Dr. Huadong Peng began his tenure as a Senior Research Fellow at the Food and Beverage Accelerator (FaBA) and Australian Institute for Bioengineering and Nanotechnology (AIBN) at the University of Queensland, Australia, in January 2024. He earned his PhD from Monash University in 2018, followed by postdoctoral training at Imperial College London and the Technical University of Denmark until 2023. Prior to his PhD, Dr. Peng obtained a Master’s Degree from the University of Chinese Academy of Sciences in 2013 and a Bachelor’s Degree from China Three Gorges University in 2010. Additionally, he served as a research associate at Novozymes China from November 2013 to January 2015.
Dr. Peng's research is focused on synthetic biology, metabolic engineering, microbial communities, lipid metabolism, microbial food and industrial biotechnology. He has received numerous awards, including the prestigious Marie Skłodowska-Curie Fellowship. He has published more than 30 peer-reviewed papers and patents in well-known journals such as Nat. Microbial., Nat. Chem. Biol., Biotechnol Biofuels, Appl. Energy, Bioresour. Technol., Biotechnol. J, etc. Furthermore, he has delivered numerous oral presentations at international conferences, showcasing his extensive research and its impact in metabolic engineering, synthetic biology, microbial food and biotechnology.
Journal Article: Yeast Platforms for Production and Screening of Bioactive Derivatives of Rauwolscine
Bradley, Samuel A., Hansson, Frederik G., Lehka, Beata J., Rago, Daniela, Pinho, Pedro, Peng, Huadong, Adhikari, Khem B., Haidar, Ahmad K., Hansen, Lea G., Volkova, Daria, Holtz, Maxence, Muyo Abad, Sergi, Ma, Xin, Koudounas, Konstantinos, Besseau, Sébastien, Gautron, Nicolas, Mélin, Céline, Marc, Jillian, Birer Williams, Caroline, Courdavault, Vincent, Jensen, Emil D., Keasling, Jay D., Zhang, Jie and Jensen, Michael K. (2024). Yeast Platforms for Production and Screening of Bioactive Derivatives of Rauwolscine. ACS Synthetic Biology. doi: 10.1021/acssynbio.4c00039
Journal Article: A molecular toolkit of cross-feeding strains for engineering synthetic yeast communities
Peng, Huadong, Darlington, Alexander P. S., South, Eric J., Chen, Hao-Hong, Jiang, Wei and Ledesma-Amaro, Rodrigo (2024). A molecular toolkit of cross-feeding strains for engineering synthetic yeast communities. Nature Microbiology, 9 (3), 848-863. doi: 10.1038/s41564-023-01596-4
Journal Article: Exploring engineering strategies that enhance de novo production of exotic cyclopropane fatty acids in <i>Saccharomyces cerevisiae</i>
Jiang, Wei, Peng, Huadong, He, Lizhong, Lesma‐Amaro, Rodrigo and Haritos, Victoria S. (2024). Exploring engineering strategies that enhance de novo production of exotic cyclopropane fatty acids in Saccharomyces cerevisiae. Biotechnology Journal, 19 (2) 2300694. doi: 10.1002/biot.202300694
Yeast Platforms for Production and Screening of Bioactive Derivatives of Rauwolscine
Bradley, Samuel A., Hansson, Frederik G., Lehka, Beata J., Rago, Daniela, Pinho, Pedro, Peng, Huadong, Adhikari, Khem B., Haidar, Ahmad K., Hansen, Lea G., Volkova, Daria, Holtz, Maxence, Muyo Abad, Sergi, Ma, Xin, Koudounas, Konstantinos, Besseau, Sébastien, Gautron, Nicolas, Mélin, Céline, Marc, Jillian, Birer Williams, Caroline, Courdavault, Vincent, Jensen, Emil D., Keasling, Jay D., Zhang, Jie and Jensen, Michael K. (2024). Yeast Platforms for Production and Screening of Bioactive Derivatives of Rauwolscine. ACS Synthetic Biology. doi: 10.1021/acssynbio.4c00039
A molecular toolkit of cross-feeding strains for engineering synthetic yeast communities
Peng, Huadong, Darlington, Alexander P. S., South, Eric J., Chen, Hao-Hong, Jiang, Wei and Ledesma-Amaro, Rodrigo (2024). A molecular toolkit of cross-feeding strains for engineering synthetic yeast communities. Nature Microbiology, 9 (3), 848-863. doi: 10.1038/s41564-023-01596-4
Jiang, Wei, Peng, Huadong, He, Lizhong, Lesma‐Amaro, Rodrigo and Haritos, Victoria S. (2024). Exploring engineering strategies that enhance de novo production of exotic cyclopropane fatty acids in Saccharomyces cerevisiae. Biotechnology Journal, 19 (2) 2300694. doi: 10.1002/biot.202300694
Spontaneously established syntrophic yeast communities improve bioproduction
Aulakh, Simran Kaur, Sellés Vidal, Lara, South, Eric J., Peng, Huadong, Varma, Sreejith Jayasree, Herrera-Dominguez, Lucia, Ralser, Markus and Ledesma-Amaro, Rodrigo (2023). Spontaneously established syntrophic yeast communities improve bioproduction. Nature Chemical Biology, 19 (8), 951-961. doi: 10.1038/s41589-023-01341-2
Peng, Huadong, Chen, Ruiqi, Shaw, William M., Hapeta, Piotr, Jiang, Wei, Bell, David J., Ellis, Tom and Ledesma-Amaro, Rodrigo (2023). Modular Metabolic Engineering and Synthetic Coculture Strategies for the Production of Aromatic Compounds in Yeast. Acs Synthetic Biology, 12 (6), 1739-1749. doi: 10.1021/acssynbio.3c00047
Valorisation of Biomass Waste for Sustainable Bioenergy and Biofuel Production
Sun, Pei-Ti and Peng, Huadong (2023). Valorisation of Biomass Waste for Sustainable Bioenergy and Biofuel Production. Bioengineering, 10 (5) ARTN 619, 619. doi: 10.3390/bioengineering10050619
Su, Rui, Wang, Ting, Bo, Taidong, Cai, Ningyun, Yuan, Meng, Wu, Chen, Jiang, Hao, Peng, Huadong, Chen, Ning and Li, Yanjun (2023). Enhanced production of d-pantothenic acid in Corynebacterium glutamicum using an efficient CRISPR-Cpf1 genome editing method. Microbial Cell Factories, 22 (1) ARTN 3. doi: 10.1186/s12934-023-02017-1
Engineering Biology of Yeast for Advanced Biomanufacturing
Jiang, Wei, Li, Yanjun and Peng, Huadong (2022). Engineering Biology of Yeast for Advanced Biomanufacturing. Bioengineering, 10 (1), 10. doi: 10.3390/bioengineering10010010
Jiang, Wei, Li, Chao, Li, Yanjun and Peng, Huadong (2022). Metabolic engineering strategies for improved lipid production and cellular physiological responses in yeast Saccharomyces cerevisiae. Journal of Fungi, 8 (5) 427, 1-22. doi: 10.3390/jof8050427
Metabolic engineering strategies to enable microbial utilization of C1 feedstocks
Jiang, Wei, Hernández Villamor, David, Peng, Huadong, Chen, Jian, Liu, Long, Haritos, Victoria and Ledesma-Amaro, Rodrigo (2021). Metabolic engineering strategies to enable microbial utilization of C1 feedstocks. Nature Chemical Biology, 17 (8), 845-855. doi: 10.1038/s41589-021-00836-0
Novel scale-up strategy based on three-dimensional shear space for animal cell culture
Li, Chao, Teng, Xiaonuo, Peng, Huadong, Yi, Xiaoping, Zhuang, Yingping, Zhang, Siliang and Xia, Jianye (2020). Novel scale-up strategy based on three-dimensional shear space for animal cell culture. Chemical Engineering Science, 212 115329, 115329. doi: 10.1016/j.ces.2019.115329
Zhang, Zhi-Hong, Peng, Huadong, Woo, Meng Wai, Zeng, Xin-An, Brennan, Margaret and Brennan, Charles S. (2020). Preparation and characterization of whey protein isolate-chlorophyll microcapsules by spray drying: Effect of WPI ratios on the physicochemical and antioxidant properties. Journal of Food Engineering, 267 109729, 109729. doi: 10.1016/j.jfoodeng.2019.109729
Li, Chao, Tian, Jiangtao, Wang, Weifei, Peng, Huadong, Zhang, Ming, Hang, Haifeng, Zhang, Siliang and Xia, Jian-Ye (2019). Numerical and experimental assessment of a miniature bioreactor equipped with a mechanical agitator and non-invasive biosensors. Journal of Chemical Technology and Biotechnology, 94 (8), 2671-2683. doi: 10.1002/jctb.6076
Peng, Huadong, He, Lizhong and Haritos, Victoria S. (2019). Flow-cytometry-based physiological characterisation and transcriptome analyses reveal a mechanism for reduced cell viability in yeast engineered for increased lipid content. Biotechnology for Biofuels, 12 (1) 98, 98. doi: 10.1186/s13068-019-1435-6
Peng, Huadong, He, Lizhong and Haritos, Victoria S. (2019). Enhanced Production of High-Value Cyclopropane Fatty Acid in Yeast Engineered for Increased Lipid Synthesis and Accumulation. Biotechnology Journal, 14 (4) 1800487, e1800487. doi: 10.1002/biot.201800487
Zhang, Zhi-Hong, Peng, Huadong, Ma, Haile and Zeng, Xin-An (2019). Effect of inlet air drying temperatures on the physicochemical properties and antioxidant activity of whey protein isolate-kale leaves chlorophyll (WPI-CH) microcapsules. Journal of Food Engineering, 245, 149-156. doi: 10.1016/j.jfoodeng.2018.10.011
Kochan, Kamila, Peng, Huadong, Gwee, Eunice S. H., Izgorodina, Ekaterina, Haritos, Victoria and Wood, Bayden R. (2019). Raman spectroscopy as a tool for tracking cyclopropane fatty acids in genetically engineered: Saccharomyces cerevisiae. Analyst, 144 (3), 901-912. doi: 10.1039/c8an01477a
He, Qin, Peng, Huadong, Sheng, Mengyao, Hu, Shishan, Qiu, Jiguo and Gu, Jiayu (2019). Humidity control strategies for solid-state fermentation: Capillary water supply by water-retention materials and negative-pressure auto-controlled irrigation. Frontiers in Bioengineering and Biotechnology, 7 (OCT) 263. doi: 10.3389/fbioe.2019.00263
Peng, Huadong, He, Lizhong and Haritos, Victoria S. (2018). Metabolic engineering of lipid pathways in Saccharomyces cerevisiae and staged bioprocess for enhanced lipid production and cellular physiology. Journal of Industrial Microbiology and Biotechnology, 45 (8), 707-717. doi: 10.1007/s10295-018-2046-0
Kochan, Kamila, Peng, Huadong, Wood, Bayden R. and Haritos, Victoria S. (2018). Single cell assessment of yeast metabolic engineering for enhanced lipid production using Raman and AFM-IR imaging. Biotechnology for Biofuels, 11 (1) 106, 106. doi: 10.1186/s13068-018-1108-x
Peng, Huadong, Moghaddam, Lalehvash, Brinin, Anthony, Williams, Brett, Mundree, Sagadevan and Haritos, Victoria S. (2018). Functional assessment of plant and microalgal lipid pathway genes in yeast to enhance microbial industrial oil production. Biotechnology and Applied Biochemistry, 65 (2), 138-144. doi: 10.1002/bab.1573
Effect of acetylation/deacetylation on enzymatic hydrolysis of corn stalk
Jiang, Wei, Peng, Huadong, Li, Hongqiang and Xu, Jian (2014). Effect of acetylation/deacetylation on enzymatic hydrolysis of corn stalk. Biomass and Bioenergy, 71, 294-298. doi: 10.1016/j.biombioe.2014.09.028
Peng, Huadong, Chen, Hongzhang, Qu, Yongshui, Li, Hongqiang and Xu, Jian (2014). Bioconversion of different sizes of microcrystalline cellulose pretreated by microwave irradiation with/without NaOH. Applied Energy, 117, 142-148. doi: 10.1016/j.apenergy.2013.12.002
Peng, Huadong, Luo, Hao, Jin, Shengying, Li, Hongqiang and Xu, Jian (2014). Improved bioethanol production from corn stover by alkali pretreatment with a novel pilot-scale continuous microwave irradiation reactor. Biotechnology and Bioprocess Engineering, 19 (3), 493-502. doi: 10.1007/s12257-014-0014-8
Peng, Huadong, Li, Hongqiang, Luo, Hao and Xu, Jian (2013). A novel combined pretreatment of ball milling and microwave irradiation for enhancing enzymatic hydrolysis of microcrystalline cellulose. Bioresource Technology, 130, 81-87. doi: 10.1016/j.biortech.2012.10.167
Optimization of microwave pretreatment on wheat straw for ethanol production
Xu, Jian, Chen, Hongzhang, Kádár, Zsófia, Thomsen, Anne Belinda, Schmidt, Jens Ejbye and Peng, Huadong (2011). Optimization of microwave pretreatment on wheat straw for ethanol production. Biomass and Bioenergy, 35 (9), 3859-3864. doi: 10.1016/j.biombioe.2011.04.054