The University of Queensland

Journal Article

• The transmembrane adaptor SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs

  Liu, Liping, Lucas, Richard M., Nanson, Jeffrey D., Li, Yan, Whitfield, Jason, Curson, James E. B., Tuladhar, Neeraj, Alexandrov, Kirill, Mobli, Mehdi, Sweet, Matthew J., Kobe, Bostjan, Stow, Jennifer and Luo, Lin (2022). The transmembrane adaptor SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs. Journal of Biological Chemistry, 298 (5) 101857, 101857. doi: 10.1016/j.jbc.2022.101857

• An alternative downstream translation start site in the non‐TIR adaptor Scimp enables selective amplification of CpG DNA responses in mouse macrophages

  Curson, James E.B., Luo, Lin, Liu, Liping, Burgess, Belinda J., Bokil, Nilesh J., Wall, Adam A, Brdicka, Tomas, Kapetanovic, Ronan, Stow, Jennifer L and Sweet, Matthew J (2022). An alternative downstream translation start site in the non‐TIR adaptor Scimp enables selective amplification of CpG DNA responses in mouse macrophages. Immunology and Cell Biology, 100 (4), 267-284. doi: 10.1111/imcb.12540

• SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophages

  Lucas, Richard M., Liu, Liping, Curson, James E. B., Koh, Yvette W. H., Tuladhar, Neeraj, Condon, Nicholas D., Das Gupta, Kaustav, Burgener, Sabrina S., Schroder, Kate, Ingley, Evan, Sweet, Matthew J., Stow, Jennifer L. and Luo, Lin (2021). SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophages. Cell Reports, 36 (10) 109662, 1-20. doi: 10.1016/j.celrep.2021.109662

• Signalling, sorting and scaffolding adaptors for Toll-like receptors

  Luo, Lin, Lucas, Richard M., Liu, Liping and Stow, Jennifer L. (2019). Signalling, sorting and scaffolding adaptors for Toll-like receptors. Journal of Cell Science, 133 (5) jcs239194, jcs239194. doi: 10.1242/jcs.239194

• SCIMP is a universal Toll‐like receptor adaptor in macrophages

  Luo, Lin, Curson, James E. B., Liu, Liping, Wall, Adam A., Tuladhar, Neeraj, Lucas, Richard M., Sweet, Matthew J. and Stow, Jennifer L. (2019). SCIMP is a universal Toll‐like receptor adaptor in macrophages. Journal of Leukocyte Biology, 107 (2) JLB.2MA0819-138RR, 251-262. doi: 10.1002/jlb.2ma0819-138rr

• Albumin binding domain fusing R/K-X-X-R/K sequence for enhancing tumor delivery of doxorubicin

  Liu, Liping, Zhang, Chun, Li, Zenglan, Wang, Chunyue, Bi, Jingxiu, Yin, Shuang, Wang, Qi, Yu, Rong, Liu, Yongdong and Su, Zhiguo (2017). Albumin binding domain fusing R/K-X-X-R/K sequence for enhancing tumor delivery of doxorubicin. Molecular Pharmaceutics, 14 (11), 3739-3749. doi: 10.1021/acs.molpharmaceut.7b00497

• Purification and characterization of a long-acting ciliary neurotrophic factor via genetically fused with an albumin-binding domain

  Xu, Longfu, Zhang, Chun, Liu, Liping, Zhang, Yao, Wang, Qi, Wang, Jian, Liu, Yongdong and Su, Zhiguo (2017). Purification and characterization of a long-acting ciliary neurotrophic factor via genetically fused with an albumin-binding domain. Protein Expression and Purification, 139, 14-20. doi: 10.1016/j.pep.2017.07.006