Ommeh (Sheila Cecily) was born on the slopes of Mount Elgon which is an extinct volcano that straddles both Kenya and Uganda and it was once the tallest mountain in Africa before the glaciers melted away. She spent her early years growing up on the foothills of this majestic mountain with her grandmother who is a small-holder rural farmer. From a young age, she witnessed first-hand the effects of disease and climate change on vulnerable livestock like poultry, cattle, goats and sheep among others leading to the loss of livelihoods for the farmers in her community.
During her formative years; 1984- 2002, Ommeh had an interest and pursued Agriculture and STEM upto the tertiary level. Her mentor was her late mother who was also an accomplised scientist and quite a visionary leader. For her postgraduate and early-career years; 2003 - 2011 Ommeh was affilliated at the International Livestock Research Institute (ILRI) where she did research on poultry genetics with a focus on genetic resitance to viral diseases. Her main fields of training and research are in Molecular Genetics and Bioinformatics.
In 2012, Ommeh joined the Institute for Biotechnology Research (IBR) at Jomo Kenyatta University of Agriculture and Technology (JKUAT) as a Research Fellow. She formed the Animal Biotechnology Research Group and the flagship project was on Indigenous poutry. Ommeh led other research projects that aimed to understand the origins, domestication and biodiversity of indigenous livestock and domesticates. The focus of these projects was to characterize candidate genes for both production and adaptive traits like disease and heat stress. Along with key collaborators, she did extensive research on emerging livestock species like minor poultry species, camels and donkeys. This also involved research on the diversity and domestication of bushmeat like guineafowls and quails. She also lead extensive research on pathogen surveillance and genomics using a Onehealth approach on bats, rodents, dogs, cats, ticks, humans among others. In 2019, Ommeh was promoted to Senior Research Fellow position and took up various leadership roles. She was a Principal Supervisor, Mentor and successfully graduated over twenty students affilliated to her own projects and funds; 6 were PhDs and over 15 Msc students.
In 2023, Ommeh Joined QAAFI as an Associate Professor in Animal Biotechnology. She plans to intergrate key outputs from previous research into her current research program at CAS. Ommeh's primary research focus is on improvement of Animal Health and Production at the "Onehealth" interface. Her research group at the Center for Animal Science aims to develop Molecular Diagnostics and Vaccines that will detect and control notifiable animal diseases. She will also lead research on diversity and harnessing bushtucker AKA bushmeat as emerging livestock species and a source of quality protein.
Masila, Ednah M., Ogada, Stephen O., Ogali, Irene N., Kennedy, Grace M., Too, Eric K. and Ommeh, Cecily S. (2024). Mitochondrial DNA D-Loop Polymorphisms among the Galla Goats Reveals Multiple Maternal Origins with Implication on the Functional Diversity of the HSP70 Gene. Genetics Research, 2024, 1-15. doi: 10.1155/2024/5564596
Journal Article: Can the Revolution in mRNA-Based Vaccine Technologies Solve the Intractable Health Issues of Current Ruminant Production Systems?
Mahony, Timothy J., Briody, Tatiana E. and Ommeh, Sheila C. (2024). Can the Revolution in mRNA-Based Vaccine Technologies Solve the Intractable Health Issues of Current Ruminant Production Systems?. Vaccines, 12 (2), 152. doi: 10.3390/vaccines12020152
Journal Article: Metagenomic Characterization of Poultry Cloacal and Oropharyngeal Swabs in Kenya Reveals Bacterial Pathogens and Their Antimicrobial Resistance Genes
Panyako, Philip M., Ommeh, Sheila C., Kuria, Stephen N., Lichoti, Jacqueline K., Musina, Johns, Nair, Venugopal, Nene, Vish, Munir, Muhammad and Oyola, Samuel O. (2024). Metagenomic Characterization of Poultry Cloacal and Oropharyngeal Swabs in Kenya Reveals Bacterial Pathogens and Their Antimicrobial Resistance Genes. International Journal of Microbiology, 2024 8054338, 1-18. doi: 10.1155/2024/8054338
Genomics and Potential Downstream Applications in the Developing World
Djikeng, Appolinaire, Ommeh, Sheila, Sangura, Sitati, Njaci, Isaac and Ngara, Mtakai (2012). Genomics and Potential Downstream Applications in the Developing World. Advances in Microbial Ecology. (pp. 335-356) New York, NY United States: Springer. doi: 10.1007/978-1-4614-2182-5_20
Masila, Ednah M., Ogada, Stephen O., Ogali, Irene N., Kennedy, Grace M., Too, Eric K. and Ommeh, Cecily S. (2024). Mitochondrial DNA D-Loop Polymorphisms among the Galla Goats Reveals Multiple Maternal Origins with Implication on the Functional Diversity of the HSP70 Gene. Genetics Research, 2024, 1-15. doi: 10.1155/2024/5564596
Mahony, Timothy J., Briody, Tatiana E. and Ommeh, Sheila C. (2024). Can the Revolution in mRNA-Based Vaccine Technologies Solve the Intractable Health Issues of Current Ruminant Production Systems?. Vaccines, 12 (2), 152. doi: 10.3390/vaccines12020152
Panyako, Philip M., Ommeh, Sheila C., Kuria, Stephen N., Lichoti, Jacqueline K., Musina, Johns, Nair, Venugopal, Nene, Vish, Munir, Muhammad and Oyola, Samuel O. (2024). Metagenomic Characterization of Poultry Cloacal and Oropharyngeal Swabs in Kenya Reveals Bacterial Pathogens and Their Antimicrobial Resistance Genes. International Journal of Microbiology, 2024 8054338, 1-18. doi: 10.1155/2024/8054338
Panyako, Philip M., Ommeh, Sheila C., Kuria, Stephen N., Lichoti, Jacqueline K., Musina, Johns, Nair, Venugopal, Nene, Vish, Oyola, Samuel O. and Munir, Muhammad (2023). Metagenomic characterization reveals virus coinfections associated with Newcastle disease virus among poultry in Kenya. Journal of Basic Microbiology, 63 (12), 1383-1396. doi: 10.1002/jobm.202300390
Discovery of novel DNA viruses in small mammals from Kenya
Ochola, Griphin Ochieng, Li, Bei, Obanda, Vincent, Ommeh, Sheila, Ochieng, Harold, Yang, Xing-Lou, Onyuok, Samson Omondi, Shi, Zheng-Li, Agwanda, Bernard and Hu, Ben (2022). Discovery of novel DNA viruses in small mammals from Kenya. Virologica Sinica, 37 (4), 491-502. doi: 10.1016/j.virs.2022.06.001
Ogada, Stephen, Otecko, Newton O., Moraa Kennedy, Grace, Musina, John, Agwanda, Bernard, Obanda, Vincent, Lichoti, Jacqueline, Peng, Min‐Sheng and Ommeh, Sheila (2021). Demographic history and genetic diversity of wild African harlequin quail (Coturnix delegorguei delegorguei) populations of Kenya. Ecology and Evolution, 11 (24), 18562-18574. doi: 10.1002/ece3.8458
Zhang, You, Hu, Ben, Agwanda, Bernard, Fang, Yaohui, Wang, Jun, Kuria, Stephen, Yang, Juan, Masika, Moses, Tang, Shuang, Lichoti, Jacqueline, Fan, Zhaojun, Shi, Zhengli, Ommeh, Sheila, Wang, Hualin, Deng, Fei and Shen, Shu (2021). Viromes and surveys of RNA viruses in camel-derived ticks revealing transmission patterns of novel tick-borne viral pathogens in Kenya. Emerging Microbes & Infections, 10 (1), 1975-1987. doi: 10.1080/22221751.2021.1986428
Evolutionary genomics at the human-environment interface in Africa
Svardal, Hannes, Rusuwa, Bosco, Linderoth, Tyler, Kiran, Anmol, Charmantier, Anne, Lattorff, H. Michael G., Cagan, Alex, Ommeh, Sheila C., Kamng'ona, Arox, Katongo, Cyprian, Santos, M. Emília, Durbin, Richard, Kumwenda, Benjamin, Visscher, Peter M. and Von Der Heyden, Sophie (2020). Evolutionary genomics at the human-environment interface in Africa. Molecular Biology and Evolution, 37 (10), 3076-3080. doi: 10.1093/molbev/msaa132
Ogali, Irene N., Okumu, Paul O., Mungube, Erick O., Lichoti, Jacqueline K., Ogada, Stephen, Moraa, Grace K., Agwanda, Bernard R. and Ommeh, Sheila C. (2020). Genomic and Pathogenic Characteristics of Virulent Newcastle Disease Virus Isolated from Chicken in Live Bird Markets and Backyard Flocks in Kenya. International Journal of Microbiology, 2020, 1-11. doi: 10.1155/2020/4705768
Huang, Xunhe, Otecko, Newton O., Peng, Minsheng, Weng, Zhuoxian, Li, Weina, Chen, Jiebo, Zhong, Ming, Zhong, Fusheng, Jin, Sihua, Geng, Zhaoyu, Luo, Wei, He, Danlin, Ma, Cheng, Han, Jianlin, Ommeh, Sheila C, Zhang, Yaping, Zhang, Xiquan and Du, Bingwang (2020). Genome-wide genetic structure and selection signatures for color in 10 traditional Chinese yellow-feathered chicken breeds. GBMC genomics, 21 (1) 316, 1-12. doi: 10.1186/s12864-020-6736-4
Ma, Xi-Yao, Ning, Tiao, Adeola, Adeniyi C., Li, Jie, Esmailizadeh, Ali, Lichoti, Jacqueline K., Agwanda, Bernard R., Isakova, Jainagul, Aldashev, Almaz A., Wu, Shi-Fang, Liu, He-Qun, Abdulloevich, Najmudinov Tojiddin, Afanasevna, Manilova Elena, Ibrohimovich, Khudoidodov Behruz, Adedokun, Rahamon Akinyele Moshood, Olaogun, Sunday Charles, Sanke, Oscar J., Mangbon, Godwin F., Chen, Xi, Yang, Wei-Kang, Wang, Zhe, Peng, Min-Sheng, Ommeh, Sheila C., Li, Yan and Zhang, Ya-Ping (2020). Potential dual expansion of domesticated donkeys revealed by worldwide analysis on mitochondrial sequences. Zoological Research, 41 (1), 51-60. doi: 10.24272/j.issn.2095-8137.2020.007
Onyuok, Samson Omondi, Hu, Ben, Li, Bei, Fan, Yi, Kering, Kelvin, Ochola, Griphin Ochieng, Zheng, Xiao-Shuang, Obanda, Vincent, Ommeh, Sheila, Yang, Xing-Lou, Agwanda, Bernard and Shi, Zheng-Li (2019). Molecular detection and genetic characterization of Novel RNA viruses in wild and synanthropic rodents and shrews in Kenya. Frontiers in Microbiology, 10 2696, 1-11. doi: 10.3389/fmicb.2019.02696
Serological evidence of MERS-CoV and HKU8-related CoV co-infection in Kenyan camels
Zhang, Wei, Zheng, Xiao-Shuang, Agwanda, Bernard, Ommeh, Sheila, Zhao, Kai, Lichoti, Jacqueline, Wang, Ning, Chen, Jing, Li, Bei, Yang, Xing-Lou, Mani, Shailendra, Ngeiywa, Kisa-Juma, Zhu, Yan, Hu, Ben, Onyuok, Samson Omondi, Yan, Bing, Anderson, Danielle E, Wang, Lin-Fa, Zhou, Peng and Shi, Zheng-Li (2019). Serological evidence of MERS-CoV and HKU8-related CoV co-infection in Kenyan camels. Emerging Microbes and Infections, 8 (1), 1528-1534. doi: 10.1080/22221751.2019.1679610
Otecko, Newton O., Ogali, Irene, Ng'ang'a, Said I., Mauki, David H., Ogada, Stephen, Moraa, Grace K., Lichoti, Jacqueline, Agwanda, Bernard, Peng, Min-Shen, Ommeh, Sheila C. and Zhang, Ya-Ping (2019). Phenotypic and morphometric differentiation of indigenous chickens from Kenya and other tropical countries augments perspectives for genetic resource improvement and conservation. Poultry Science, 98 (7), 2747-2755. doi: 10.3382/ps/pez097
Wang, Xuan, Zhou, Bo-Wen, Yang, Melinda A., Yin, Ting-Ting, Chen, Fang-Liang, Ommeh, Sheila C., Esmailizadeh, Ali, Turner, Melissa M., Poyarkov, Andrei D., Savolainen, Peter, Wang, Guo-Dong, Fu, Qiaomei and Zhang, Ya-Ping (2019). Canine transmissible venereal tumor genome reveals ancient introgression from coyotes to pre-contact dogs in North America. Cell Research, 29 (7), 592-595. doi: 10.1038/s41422-019-0183-2
Ommeh, Sheila, Zhang, Wei, Zohaib, Ali, Chen, Jing, Zhang, Huajun, Hu, Ben, Ge, Xing-Yi, Yang, Xing-Lou, Masika, Moses, Obanda, Vincent, Luo, Yun, Li, Shan, Waruhiu, Cecilia, Li, Bei, Zhu, Yan, Ouma, Desterio, Odendo, Vincent, Wang, Lin-Fa, Anderson, Danielle E, Lichoti, Jacqueline, Mungube, Erick, Gakuya, Francis, Zhou, Peng, Ngeiywa, Kisa-Juma, Yan, Bing, Agwanda, Bernard and Shi, Zheng-Li (2019). Correction to: genetic evidence of Middle East Respiratory Syndrome Coronavirus (MERS-Cov) and widespread seroprevalence among camels in Kenya. Virologica Sinica, 34 (1), 115-115. doi: 10.1007/s12250-019-00092-6
Ommeh, Sheila, Zhang, Wei, Zohaib, Ali, Chen, Jing, Zhang, Huajun, Hu, Ben, Ge, Xing-Yi, Yang, Xing-Lou, Masika, Moses, Obanda, Vincent, Luo, Yun, Li, Shan, Waruhiu, Cecilia, Li, Bei, Zhu, Yan, Ouma, Desterio, Odendo, Vincent, Wang, Lin-Fa, Anderson, Danielle E, Lichoti, Jacqueline, Mungube, Erick, Gakuya, Francis, Zhou, Peng, Ngeiywa, Kisa-Juma, Yan, Bing, Agwanda, Bernard and Shi, Zheng-Li (2018). Genetic evidence of Middle East Respiratory Syndrome Coronavirus (MERS-Cov) and widespread seroprevalence among camels in Kenya. Virologica Sinica, 33 (6), 484-492. doi: 10.1007/s12250-018-0076-4
Murunga, Philip, Kennedy, Grace Moraa, Imboma, Titus, Malaki, Phillista, Kariuki, Daniel, Ndiema, Emmanuel, Obanda, Vincent, Agwanda, Bernard, Lichoti, Jacqueline Kasiiti and Ommeh, Sheila Cecily (2018). Mitochondrial DNA D-Loop Diversity of the Helmeted Guinea Fowls in Kenya and Its Implications on HSP70 Gene Functional Polymorphism. BioMed Research International, 2018 7314038, 1-12. doi: 10.1155/2018/7314038
Ogali, Irene N., Wamuyu, Lucy W., Lichoti, Jacqueline K., Mungube, Erick O., Agwanda, Bernard and Ommeh, Sheila C. (2018). Molecular Characterization of Newcastle Disease Virus from Backyard Poultry Farms and Live Bird Markets in Kenya. International Journal of Microbiology, 2018 2368597, 1-11. doi: 10.1155/2018/2368597
Waruhiu, Cecilia, Ommeh, Sheila, Obanda, Vincent, Agwanda, Bernard, Gakuya, Francis, Ge, Xing-Yi, Yang, Xing-Lou, Wu, Li-Jun, Zohaib, Ali, Hu, Ben and Shi, Zheng-Li (2018). Correction to: Molecular detection of viruses in Kenyan bats and discovery of novel astroviruses, caliciviruses and rotaviruses. Virologica Sinica, 33 (3), 294-294. doi: 10.1007/s12250-018-0035-0
Waruhiu, Cecilia, Ommeh, Sheila, Obanda, Vincent, Agwanda, Bernard, Gakuya, Francis, Ge, Xing-Yi, Yang, Xing-Lou, Wu, Li-Jun, Zohaib, Ali, Hu, Ben and Shi, Zheng-Li (2017). Molecular detection of viruses in Kenyan bats and discovery of novel astroviruses, caliciviruses and rotaviruses. Virologica Sinica, 32 (2), 101-114. doi: 10.1007/s12250-016-3930-2
Mitochondrial DNA variation of Nigerian domestic helmeted guinea fowl
Adeola, Adeniyi C., Ommeh, Sheila C., Murphy, Robert W., Wu, Shi‐Fang, Peng, Min‐Sheng and Zhang, Ya‐Ping (2015). Mitochondrial DNA variation of Nigerian domestic helmeted guinea fowl. Animal Genetics, 46 (5), 576-579. doi: 10.1111/age.12324
Wamuyu, Lucy, Obanda, Vincent, Kariuki, Daniel, Gakuya, Francis, Makanda, Moni, Otiende, Moses and Ommeh, Sheila (2015). Molecular Detection and Characterization of Theileria Infecting Wildebeest (Connochaetes taurinus) in the Maasai Mara National Reserve, Kenya. Pathogens, 4 (3), 626-638. doi: 10.3390/pathogens4030626
Masanga, Joel Okoyo, Matheka, Jonathan Mutie, Omer, Rasha Adam, Ommeh, Sheila Cecily, Monda, Ethel Oranga and Alakonya, Amos Emitati (2015). Downregulation of transcription factor aflR in Aspergillus flavus confers reduction to aflatoxin accumulation in transgenic maize with alteration of host plant architecture. Plant Cell Reports, 34 (8), 1379-1387. doi: 10.1007/s00299-015-1794-9
Genome sequence of the tsetse fly (Glossina morsitans): vector of African trypanosomiasis
International Glossina Genome Initiative and Ommeh, Sheila (2014). Genome sequence of the tsetse fly (Glossina morsitans): vector of African trypanosomiasis. Science, 344 (6182), 380-386. doi: 10.1126/science.1249656
Basic molecular evolution workshop - a trans-African virtual training course
Ommeh, Sheila, Budd, Aidan, Ngara, Mtakai Vald, Njaci, Isaac and de Villiers, Etienne P. (2011). Basic molecular evolution workshop - a trans-African virtual training course. Bioessays, 33 (4), 243-247. doi: 10.1002/bies.201000139
Ten simple rules for organizing a virtual conference—anywhere
Gichora, Nelson N., Fatumo, Segun A., Ngara, Mtakai V., Chelbat, Noura, Ramdayal, Kavisha, Opap, Kenneth B., Siwo, Geoffrey H., Adebiyi, Marion O., El Gonnouni, Amina, Zofou, Denis, Maurady, Amal A. M., Adebiyi, Ezekiel F., de Villiers, Etienne P., Masiga, Daniel K., Bizzaro, Jeffrey W., Suravajhala, Prashanth, Ommeh, Sheila C. and Hide, Winston (2010). Ten simple rules for organizing a virtual conference—anywhere. PLoS Computational Biology, 6 (2) e1000650. doi: 10.1371/journal.pcbi.1000650
Razafindraibe, Hanta, Mobegi, Victor A., Ommeh, Sheila C., Rakotondravao,, Bjørnstad, Gro, Hanotte, Olivier and Jianlin, Han (2008). Mitochondrial DNA origin of indigenous Malagasy chicken: implication for a functional polymorphism at the Mx gene. Annals of the New York Academy of Sciences, 1149 (1), 77-79. doi: 10.1196/annals.1428.047
Effect of folate derivatives on the activity of antifolate drugs used against malaria and cancer
Nduati, Eunice, Diriye, Abdi, Ommeh, Sheila, Mwai, Leah, Kiara, Steven, Masseno, Victor, Kokwaro, Gilbert and Nzila, Alexis (2008). Effect of folate derivatives on the activity of antifolate drugs used against malaria and cancer. Parasitology Research, 102 (6), 1227-1234. doi: 10.1007/s00436-008-0897-4
Ommeh, Sheila, Nduati, Eunice, Mberu, Eddy, Kokwaro, Gilbert, Marsh, Kevin, Rosowsky, Andre and Nzila, Alexis (2004). In vitro activities of 2,4-diaminoquinazoline and 2,4-diaminopteridine derivatives against Plasmodium falciparum. Antimicrobial Agents and Chemotherapy, 48 (10) 3711, 1-4. doi: 10.1128/AAC.48.10.3711-3714.2004