Journal Article: A chimeric vaccine protects farmed saltwater crocodiles from West Nile virus-induced skin lesions
Habarugira, Gervais, Harrison, Jessica J., Moran, Jasmin, Suen, Willy W., Colmant, Agathe M. G., Hobson-Peters, Jody, Isberg, Sally R., Bielefeldt-Ohmann, Helle and Hall, Roy A. (2023). A chimeric vaccine protects farmed saltwater crocodiles from West Nile virus-induced skin lesions. npj Vaccines, 8 (1) 93, 1-9. doi: 10.1038/s41541-023-00688-w
Journal Article: Serological characterization of lineage II insect-specific flaviviruses compared with pathogenic mosquito-borne flaviviruses
Tabata, Koshiro, Itakura, Yukari, Toba, Shinsuke, Uemura, Kentaro, Kishimoto, Mai, Sasaki, Michihito, Harrison, Jessica J., Sato, Akihiko, Hall, William W., Hall, Roy A., Sawa, Hirofumi and Orba, Yasuko (2022). Serological characterization of lineage II insect-specific flaviviruses compared with pathogenic mosquito-borne flaviviruses. Biochemical and Biophysical Research Communications, 616, 115-121. doi: 10.1016/j.bbrc.2022.05.080
Kurucz, Nina, McMahon, Jamie Lee, Warchot, Allan, Hewitson, Glen, Barcelon, Jean, Moore, Frederick, Moran, Jasmin, Harrison, Jessica J., Colmant, Agathe M. G., Staunton, Kyran M., Ritchie, Scott A., Townsend, Michael, Steiger, Dagmar Meyer, Hall, Roy A., Isberg, Sally R. and Hall-Mendelin, Sonja (2022). Nucleic acid preservation card surveillance is effective for monitoring arbovirus transmission on crocodile farms and provides a one health benefit to northern Australia. Viruses, 14 (6) 1342, 1-14. doi: 10.3390/v14061342
New vaccines and diagnostics to control viral disease in farmed crocodiles
(2023–2027) ARC Linkage Projects
Broad-spectrum vaccine design for flaviviruses and henipaviruses
(2023–2025) NHMRC MRFF EMCR - Early to Mid-Career Researchers
Insect-specific virus host restriction
(2023–2025) ARC Discovery Early Career Researcher Award
A chimeric vaccine protects farmed saltwater crocodiles from West Nile virus-induced skin lesions
Habarugira, Gervais, Harrison, Jessica J., Moran, Jasmin, Suen, Willy W., Colmant, Agathe M. G., Hobson-Peters, Jody, Isberg, Sally R., Bielefeldt-Ohmann, Helle and Hall, Roy A. (2023). A chimeric vaccine protects farmed saltwater crocodiles from West Nile virus-induced skin lesions. npj Vaccines, 8 (1) 93, 1-9. doi: 10.1038/s41541-023-00688-w
Tabata, Koshiro, Itakura, Yukari, Toba, Shinsuke, Uemura, Kentaro, Kishimoto, Mai, Sasaki, Michihito, Harrison, Jessica J., Sato, Akihiko, Hall, William W., Hall, Roy A., Sawa, Hirofumi and Orba, Yasuko (2022). Serological characterization of lineage II insect-specific flaviviruses compared with pathogenic mosquito-borne flaviviruses. Biochemical and Biophysical Research Communications, 616, 115-121. doi: 10.1016/j.bbrc.2022.05.080
Kurucz, Nina, McMahon, Jamie Lee, Warchot, Allan, Hewitson, Glen, Barcelon, Jean, Moore, Frederick, Moran, Jasmin, Harrison, Jessica J., Colmant, Agathe M. G., Staunton, Kyran M., Ritchie, Scott A., Townsend, Michael, Steiger, Dagmar Meyer, Hall, Roy A., Isberg, Sally R. and Hall-Mendelin, Sonja (2022). Nucleic acid preservation card surveillance is effective for monitoring arbovirus transmission on crocodile farms and provides a one health benefit to northern Australia. Viruses, 14 (6) 1342, 1-14. doi: 10.3390/v14061342
Habarugira, Gervais, Moran, Jasmin, Harrison, Jessica J., Isberg, Sally R., Hobson-Peters, Jody, Hall, Roy A. and Bielefeldt-Ohmann, Helle (2022). Evidence of Infection with Zoonotic Mosquito-Borne Flaviviruses in Saltwater Crocodiles (Crocodylus porosus) in Northern Australia. Viruses, 14 (5) 1106. doi: 10.3390/v14051106
Slonchak, Andrii, Parry, Rhys, Pullinger, Brody, Sng, Julian D. J., Wang, Xiaohui, Buck, Teresa F., Torres, Francisco J., Harrison, Jessica J., Colmant, Agathe M. G., Hobson-Peters, Jody, Hall, Roy A., Tuplin, Andrew and Khromykh, Alexander A. (2022). Structural analysis of 3’UTRs in insect flaviviruses reveals novel determinants of sfRNA biogenesis and provides new insights into flavivirus evolution. Nature Communications, 13 (1) 1279, 1-16. doi: 10.1038/s41467-022-28977-3
O’Brien, Caitlin A., Huang, Bixing, Warrilow, David, Hazlewood, Jessamine E., Bielefeldt-Ohmann, Helle, Hall-Mendelin, Sonja, Pegg, Cassandra L., Harrison, Jessica J., Paramitha, Devina, Newton, Natalee D., Schulz, Benjamin L., Suhrbier, Andreas, Hobson-Peters, Jody and Hall, Roy A. (2022). Extended characterisation of five archival tick-borne viruses provides insights for virus discovery in Australian ticks. Parasites and Vectors, 15 (1) 59, 59. doi: 10.1186/s13071-022-05176-z
The chimeric Binjari-Zika vaccine provides long-term protection against ZIKA virus challenge
Hazlewood, Jessamine E., Tang, Bing, Yan, Kexin, Rawle, Daniel J., Harrison, Jessica J., Hall, Roy A., Hobson-Peters, Jody and Suhrbier, Andreas (2022). The chimeric Binjari-Zika vaccine provides long-term protection against ZIKA virus challenge. Vaccines, 10 (1) 85. doi: 10.3390/vaccines10010085
Chimeric vaccines based on novel insect-specific flaviviruses
Harrison, Jessica J., Hobson-Peters, Jody, Bielefeldt-Ohmann, Helle and Hall, Roy A. (2021). Chimeric vaccines based on novel insect-specific flaviviruses. Vaccines, 9 (11) 1230, 1230. doi: 10.3390/vaccines9111230
Improved detection of flaviviruses in Australian mosquito populations via replicative intermediates
O'Brien, Caitlin A., Harrison, Jessica J., Colmant, Agathe M. G., Traves, Renee J., Paramitha, Devina, Hall-Mendelin, Sonja, Bielefeldt-Ohmann, Helle, Vet, Laura J., Piyasena, Thisun B. H., Newton, Natalee D., Yam, Alice W., Hobson-Peters, Jody and Hall, Roy A. (2021). Improved detection of flaviviruses in Australian mosquito populations via replicative intermediates. Journal of General Virology, 102 (7) 001617. doi: 10.1099/jgv.0.001617
A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses
Amarilla, Alberto A., Sng, Julian D. J., Parry, Rhys, Deerain, Joshua M., Potter, James R., Setoh, Yin Xiang, Rawle, Daniel J., Le, Thuy T., Modhiran, Naphak, Wang, Xiaohui, Peng, Nias Y. G., Torres, Francisco J., Pyke, Alyssa, Harrison, Jessica J., Freney, Morgan E., Liang, Benjamin, McMillan, Christopher L. D., Cheung, Stacey T. M., Guevara, Darwin J Da Costa, Hardy, Joshua M., Bettington, Mark, Muller, David A., Coulibaly, Fasséli, Moore, Frederick, Hall, Roy A., Young, Paul R., Mackenzie, Jason M., Hobson-Peters, Jody, Suhrbier, Andreas ... Khromykh, Alexander A. (2021). A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses. Nature Communications, 12 (1) 3431, 3431. doi: 10.1038/s41467-021-23779-5
Choo, Jovin J. Y., Vet, Laura J., McMillan, Christopher L. D., Harrison, Jessica J., Scott, Connor A. P., Depelsenaire, Alexandra C. I., Fernando, Germain J. P., Watterson, Daniel, Hall, Roy A., Young, Paul R., Hobson-Peters, Jody and Muller, David A. (2021). A chimeric dengue virus vaccine candidate delivered by high density microarray patches protects against infection in mice. npj Vaccines, 6 (1) 66, 66. doi: 10.1038/s41541-021-00328-1
The structure of an infectious immature flavivirus redefines viral architecture and maturation
Newton, Natalee D., Hardy, Joshua M., Modhiran, Naphak, Hugo, Leon E., Amarilla, Alberto A., Bibby, Summa, Venugopal, Hariprasad, Harrison, Jessica J., Traves, Renee J., Hall, Roy A., Hobson-Peters, Jody, Coulibaly, Fasséli and Watterson, Daniel (2021). The structure of an infectious immature flavivirus redefines viral architecture and maturation. Science Advances, 7 (20) eabe4507, 1-12. doi: 10.1126/sciadv.abe4507
Colmant, Agathe M. G., Hobson-Peters, Jody, Slijkerman, Teun A. P., Harrison, Jessica J., Pijlman, Gorben P., van Oers, Monique M., Simmonds, Peter, Hall, Roy A. and Fros, Jelke J. (2021). Insect-specific flavivirus replication in mammalian cells is inhibited by physiological temperature and the zinc-finger antiviral protein. Viruses, 13 (4) 573, 1-16. doi: 10.3390/v13040573
A unique relative of Rotifer birnavirus Isolated from Australian mosquitoes
O’Brien, Caitlin A., Pegg, Cassandra L., Nouwens, Amanda S., Bielefeldt-Ohmann, Helle, Huang, Bixing, Warrilow, David, Harrison, Jessica J., Haniotis, John, Schulz, Benjamin L., Paramitha, Devina, Colmant, Agathe M. G., Newton, Natalee D., Doggett, Stephen L., Watterson, Daniel, Hobson-Peters, Jody and Hall, Roy A. (2020). A unique relative of Rotifer birnavirus Isolated from Australian mosquitoes. Viruses, 12 (9) 1056, 1056. doi: 10.3390/v12091056
Harrison, Jessica J., Hobson-Peters, Jody, Colmant, Agathe M. G., Koh, Joanna, Newton, Natalee D., Warrilow, David, Bielefeldt-Ohmann, Helle, Piyasena, Thisun B. H., O’Brien, Caitlin A., Vet, Laura J., Paramitha, Devina, Potter, James R., Davis, Steven S., Johansen, Cheryl A., Setoh, Yin Xiang, Khromykh, Alexander A. and Hall, Roy A. (2020). Antigenic characterization of new lineage II insect-specific flaviviruses in Australian mosquitoes and identification of host restriction factors. mSphere, 5 (3) e00095, 1-19. doi: 10.1128/msphere.00095-20
Protective efficacy of a chimeric insect-specific flavivirus vaccine against West Nile virus
Vet, Laura J., Setoh, Yin Xiang, Amarilla, Alberto A., Habarugira, Gervais, Suen, Willy W., Newton, Natalee D., Harrison, Jessica J., Hobson-Peters, Jody, Hall, Roy A. and Bielefeldt-Ohmann, Helle (2020). Protective efficacy of a chimeric insect-specific flavivirus vaccine against West Nile virus. Vaccines, 8 (2) 258, 258. doi: 10.3390/vaccines8020258
NS4/5 mutations enhance flavivirus Bamaga virus infectivity and pathogenicity in vitro and in vivo
Colmant, Agathe M. G., Bielefeldt-Ohmann, Helle, Vet, Laura J., O’Brien, Caitlin A., Bowen, Richard A., Hartwig, Airn E., Davis, Steven, Piyasena, Thisun B. H., Habarugira, Gervais, Harrison, Jessica J., Hobson-Peters, Jody and Hall, Roy A. (2020). NS4/5 mutations enhance flavivirus Bamaga virus infectivity and pathogenicity in vitro and in vivo. PLoS Neglected Tropical Diseases , 14 (3) e0008166, 1-28. doi: 10.1371/journal.pntd.0008166
Colmant, Agathe M. G., O'Brien, Caitlin A., Newton, Natalee D., Watterson, Daniel, Hardy, Joshua, Coulibaly, Fasséli, Bielefeldt-Ohmann, Helle, Warrilow, David, Huang, Bixing, Paramitha, Devina, Harrison, Jessica J., Hall, Roy A. and Hobson-Peters, Jody (2020). Novel monoclonal antibodies against Australian strains of negeviruses and insights into virus structure, replication and host -restriction. Journal of General Virology, 101 (4), 440-452. doi: 10.1099/jgv.0.001388
Hobson-Peters, Jody, Harrison, Jessica J., Watterson, Daniel, Hazlewood, Jessamine E., Vet, Laura J., Newton, Natalee D., Warrilow, David, Colmant, Agathe M. G., Taylor, Carmel, Huang, Bixing, Piyasena, Thisun B. H., Chow, Weng Kong, Setoh, Yin Xiang, Tang, Bing, Nakayama, Eri, Yan, Kexin, Amarilla, Alberto A., Wheatley, Sarah, Moore, Peter R., Finger, Mitchell, Kurucz, Nina, Modhiran, Naphak, Young, Paul R., Khromykh, Alexander A., Bielefeldt-Ohmann, Helle, Suhrbier, Andreas and Hall, Roy A. (2019). A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus. Science Translational Medicine, 11 (522) eaax7888, 1-15. doi: 10.1126/scitranslmed.aax7888
Determinants of Zika virus host tropism uncovered by deep mutational scanning
Setoh, Yin Xiang, Amarilla, Alberto A., Peng, Nias Y. G., Griffiths, Rebecca E., Carrera, Julio, Freney, Morgan E., Nakayama, Eri, Ogawa, Shinya, Watterson, Daniel, Modhiran, Naphak, Nanyonga, Faith Elizabeth, Torres, Francisco J., Slonchak, Andrii, Periasamy, Parthiban, Prow, Natalie A., Tang, Bing, Harrison, Jessica, Hobson-Peters, Jody, Cuddihy, Thom, Cooper-White, Justin, Hall, Roy A., Young, Paul R., Mackenzie, Jason M., Wolvetang, Ernst, Bloom, Jesse D., Suhrbier, Andreas and Khromykh, Alexander A. (2019). Determinants of Zika virus host tropism uncovered by deep mutational scanning. Nature Microbiology, 4 (5), 876-887. doi: 10.1038/s41564-019-0399-4
The taxonomy of an Australian nodavirus isolated from mosquitoes
Warrilow, David, Huang, Bixing, Newton, Natalee D., Harrison, Jessica J., Johnson, Karyn N., Chow, Weng Kong, Hall, Roy A. and Hobson-Peters, Jody (2018). The taxonomy of an Australian nodavirus isolated from mosquitoes. PLoS One, 13 (12) e0210029, 1-9. doi: 10.1371/journal.pone.0210029
Colmant, Agathe M. G., Hall-Mendelin, Sonja, Ritchie, Scott A., Bielefeldt-Ohmann, Helle, Harrison, Jessica J., Newton, Natalee D., O’Brien, Caitlin A., Cazier, Chris, Johansen, Cheryl A., Hobson-Peters, Jody, Hall, Roy A. and van den Hurk, Andrew F. (2018). The recently identified flavivirus Bamaga virus is transmitted horizontally by Culex mosquitoes and interferes with West Nile virus replication in vitro and transmission in vivo. PLoS Neglected Tropical Diseases, 12 (10) e0006886, e0006886. doi: 10.1371/journal.pntd.0006886
New genotypes of Liao ning virus (LNV) in Australia exhibit an insect-specific phenotype
Prow, Natalie A., Mah, Marcus G., Deerain, Joshua M., Warrilow, David, Colmant, Agathe M. G., O'Brien, Caitlin A., Harrison, Jessica J., McLean, Breeanna J., Hewlett, Elise K., Piyasena, Thisun B. H., Hall-Mendelin, Sonja, van den Hurk, Andrew F., Watterson, Daniel, Huang, Bixing, Schulz, Benjamin L., Webb, Cameron E., Johansen, Cheryl A., Chow, Weng K., Hobson-Peters, Jody, Cazier, Chris, Coffey, Lark L., Faddy, Helen M., Suhrbier, Andreas, Bielefeldt-Ohmann, Helle and Hall, Roy A. (2018). New genotypes of Liao ning virus (LNV) in Australia exhibit an insect-specific phenotype. The Journal of General Virology, 99 (4), 596-609. doi: 10.1099/jgv.0.001038
Discovery and characterisation of castlerea virus, a new species of Negevirus isolated in Australia
O'Brien, Caitlin A., McLean, Breeanna J., Colmant, Agathe M. G., Harrison, Jessica J., Hall-Mendelin, Sonja, van den Hurk, Andrew F., Johansen, Cheryl A., Watterson, Daniel, Bielefeldt-Ohmann, Helle, Newton, Natalee D., Schulz, Benjamin L., Hall, Roy A. and Hobson-Peters, Jody (2017). Discovery and characterisation of castlerea virus, a new species of Negevirus isolated in Australia. Evolutionary Bioinformatics, 13, 1176934317691269. doi: 10.1177/1176934317691269
Hall, Roy A., Bielefeldt-Ohmann, Helle, McLean, Breeanna J., O'Brien, Caitlin A., Colmant, Agathe M.G., Piyasena, Thisun B.H., Harrison, Jessica J., Newton, Natalee D., Barnard, Ross T., Prow, Natalie A., Deerain, Joshua M., Mah, Marcus G.K.Y. and Hobson-Peters, Jody (2017). Commensal viruses of mosquitoes: Host restriction, transmission, and interaction with arboviral pathogens. Evolutionary Bioinformatics, 12 (Suppl 2), 35-44. doi: 10.4137/EBO.S40740
Harrison, Jessica J., Warrilow, David, McLean, Breeanna J., Watterson, Daniel, O'Brien, Caitlin A., Colmant, Agathe M.G., Johansen, Cheryl A., Barnard, Ross T., Hall-Mendelin, Sonja, Davis, Steven S., Hall, Roy A. and Hobson-Peters, Jody (2016). A new Orbivirus isolated from mosquitoes in north-western Australia shows antigenic and genetic similarity to Corriparta virus but does not replicate in vertebrate cells. Viruses, 8 (5) 141, e141.1-e141.15. doi: 10.3390/v8050141
Hobson-Peters, Jody, Warrilow, David, McLean, Breeanna J., Watterson, Daniel, Colmant, Agathe M.G., van den Hurk, Andrew F., Hall-Mendelin, Sonja, Hastie, Marcus L., Gorman, Jeffrey J., Harrison, Jessica J., Prow, Natalie A., Barnard, Ross T., Allcock, Richard, Johansen, Cheryl A. and Hall, Roy A. (2016). Discovery and characterisation of a new insect-specific bunyavirus from Culex mosquitoes captured in northern Australia. Virology, 489, 269-281. doi: 10.1016/j.virol.2015.11.003
Harrison, Jessica Jane (2019). Discovery and characterisation of novel insect-specific viruses and investigation of their host-restriction. PhD Thesis, School of Chemistry and Molecular Biosciences, The University of Queensland. doi: 10.14264/uql.2019.114
New vaccines and diagnostics to control viral disease in farmed crocodiles
(2023–2027) ARC Linkage Projects
Broad-spectrum vaccine design for flaviviruses and henipaviruses
(2023–2025) NHMRC MRFF EMCR - Early to Mid-Career Researchers
Insect-specific virus host restriction
(2023–2025) ARC Discovery Early Career Researcher Award
ChimerDx - Next generation rapid diagnostics using chimeric viral antigens
(2023–2024) Australia's Economic Accelerator Seed Grants