The University of Queensland

Targeting the Plasmodium falciparum UCHL3 ubiquitin hydrolase using chemically constrained peptides

King, Harry R., Bycroft, Mark, Nguyen, Thanh-Binh, Kelly, Geoff, Vinogradov, Alexander A., Rowling, Pamela J E, Stott, Katherine, Ascher, David B., Suga, Hiroaki, Itzhaki, Laura S. and Artavanis-Tsakonas, Katerina (2024). Targeting the Plasmodium falciparum UCHL3 ubiquitin hydrolase using chemically constrained peptides. Proceedings of the National Academy of Sciences of the United States of America, 121 (21) e2322923121. doi: 10.1073/pnas.2322923121

Mechanisms of biased agonism by Gα_i/o-biased stapled peptide agonists of the relaxin-3 receptor

Jayakody, Tharindunee, Inoue, Asuka, Kannan, Srinivasaraghavan, Nakamura, Gaku, Kawakami, Kouki, Mendis, Krishan, Nguyen, Thanh-Binh, Li, Jianguo, Herr, Deron R., Verma, Chandra S. and Dawe, Gavin S. (2024). Mechanisms of biased agonism by Gαi/o-biased stapled peptide agonists of the relaxin-3 receptor. Science Signaling, 17 (823) eabl5880. doi: 10.1126/scisignal.abl5880

LEGO-CSM: a tool for functional characterization of proteins

Nguyen, Thanh Binh, de Sá, Alex G. C., Rodrigues, Carlos H. M., Pires, Douglas E. V. and Ascher, David B. (2023). LEGO-CSM: a tool for functional characterization of proteins. Bioinformatics, 39 (7) btad402, 1-4. doi: 10.1093/bioinformatics/btad402

A bias of Asparagine to Lysine mutations in SARS-CoV-2 outside the receptor binding domain affects protein flexibility

Boer, Jennifer C., Pan, Qisheng, Holien, Jessica K., Nguyen, Thanh-Binh, Ascher, David B. and Plebanski, Magdalena (2022). A bias of Asparagine to Lysine mutations in SARS-CoV-2 outside the receptor binding domain affects protein flexibility. Frontiers in Immunology, 13 954435, 1-13. doi: 10.3389/fimmu.2022.954435

kinCSM : Using graph‐based signatures to predict small molecule CDK2 inhibitors

Zhou, Yunzhuo, Al‐Jarf, Raghad, Alavi, Azadeh, Nguyen, Thanh Binh, Rodrigues, Carlos H. M., Pires, Douglas E. V. and Ascher, David B. (2022). kinCSM : Using graph‐based signatures to predict small molecule CDK2 inhibitors. Protein Science, 31 (11) e4453, 1-11. doi: 10.1002/pro.4453

Systematic evaluation of computational tools to predict the effects of mutations on protein stability in the absence of experimental structures

Pan, Qisheng, Nguyen, Thanh Binh, Ascher, David B and Pires, Douglas E V (2022). Systematic evaluation of computational tools to predict the effects of mutations on protein stability in the absence of experimental structures. Briefings in Bioinformatics, 23 (2) bbac025. doi: 10.1093/bib/bbac025

Structure-guided machine learning prediction of drug resistance mutations in Abelson 1 kinase

Zhou, Yunzhuo, Portelli, Stephanie, Pat, Megan, Rodrigues, Carlos H.M., Nguyen, Thanh-Binh, Pires, Douglas E.V. and Ascher, David B. (2021). Structure-guided machine learning prediction of drug resistance mutations in Abelson 1 kinase. Computational and Structural Biotechnology Journal, 19, 5381-5391. doi: 10.1016/j.csbj.2021.09.016