The University of Queensland

Perforated intravenous catheter design is acceptable for the administration of contrast-enhanced computed tomography administration in cancer patients: results of a pilot randomised controlled trial

Gavin, Nicole C., Wignall, Elizabeth, Marsh, Nicole, Marquart, Louise, Dobeli, Karen L., O'Brien, Catherine, Verderosa, Anthony D., Totsika, Makrina and Keogh, Samantha (2023). Perforated intravenous catheter design is acceptable for the administration of contrast-enhanced computed tomography administration in cancer patients: results of a pilot randomised controlled trial. The Journal of Vascular Access ARTN 11297298231171422, 112972982311714. doi: 10.1177/11297298231171422

Siderophore conjugates to combat antibiotic-resistant bacteria

Rayner, Beth, Verderosa, Anthony D., Ferro, Vito and Blaskovich, Mark A. T. (2023). Siderophore conjugates to combat antibiotic-resistant bacteria. RSC Medicinal Chemistry, 14 (5), 800-822. doi: 10.1039/d2md00465h

Metals to combat antimicrobial resistance

Frei, Angelo, Verderosa, Anthony D., Elliott, Alysha G., Zuegg, Johannes and Blaskovich, Mark A. T. (2023). Metals to combat antimicrobial resistance. Nature Reviews Chemistry, 7 (3), 1-23. doi: 10.1038/s41570-023-00463-4

A buried water network modulates the activity of the Escherichia coli disulphide catalyst DsbA

Wang, Geqing, Qin, Jilong, Verderosa, Anthony D., Hor, Lilian, Santos-Martin, Carlos, Paxman, Jason J., Martin, Jennifer L., Totsika, Makrina and Heras, Begoña (2023). A buried water network modulates the activity of the Escherichia coli disulphide catalyst DsbA. Antioxidants, 12 (2) 380, 380. doi: 10.3390/antiox12020380

Use of antiviral agents and other therapies for COVID-19

Blaskovich, Mark A. T. and Verderosa, Anthony D. (2023). Use of antiviral agents and other therapies for COVID-19. Seminars in Respiratory and Critical Care Medicine, 44 (1), 118-129. doi: 10.1055/s-0042-1758837

Repeat-unit elongations to produce bacterial complex long polysaccharide chains, an O-antigen perspective

Hong, Yaoqin, Hu, Dalong, Verderosa, Anthony D., Qin, Jilong, Totsika, Makrina and Reeves, Peter R. (2023). Repeat-unit elongations to produce bacterial complex long polysaccharide chains, an O-antigen perspective. EcoSal Plus, 11 (1), 1-16. doi: 10.1128/ecosalplus.esp-0020-2022

Loss of β-ketoacyl acyl carrier protein synthase III activity restores multidrug-resistant escherichia coli sensitivity to previously ineffective antibiotics

Hong, Yaoqin, Qin, Jilong, Verderosa, Anthony D., Hawas, Sophia, Zhang, Bing, Blaskovich, Mark A. T., Cronan, John E. and Totsika, Makrina (2022). Loss of β-ketoacyl acyl carrier protein synthase III activity restores multidrug-resistant escherichia coli sensitivity to previously ineffective antibiotics. mSphere, 7 (3), e0011722. doi: 10.1128/msphere.00117-22

Combination therapies for biofilm inhibition and eradication: a comparative review of laboratory and preclinical studies

Hawas, Sophia, Verderosa, Anthony D. and Totsika, Makrina (2022). Combination therapies for biofilm inhibition and eradication: a comparative review of laboratory and preclinical studies. Frontiers in Cellular and Infection Microbiology, 12 850030. doi: 10.3389/fcimb.2022.850030

Isothiazolone-nitroxide hybrids with activity against antibiotic-resistant Staphylococcus aureus biofilms

Verderosa, Anthony D., Hawas, Sophia, Harris, Jessica, Totsika, Makrina and Fairfull-Smith, Kathryn E. (2022). Isothiazolone-nitroxide hybrids with activity against antibiotic-resistant Staphylococcus aureus biofilms. ACS Omega, 7 (6), 5300-5310. doi: 10.1021/acsomega.1c06433

Thermoresponsive polymer-antibiotic conjugates based on gradient copolymers of 2-oxazoline and 2-oxazine

Park, Jong-Ryul, Verderosa, Anthony D., Totsika, Makrina, Hoogenboom, Richard and Dargaville, Tim R. (2021). Thermoresponsive polymer-antibiotic conjugates based on gradient copolymers of 2-oxazoline and 2-oxazine. Biomacromolecules, 22 (12), 5185-5194. doi: 10.1021/acs.biomac.1c01133

Salmonella enterica BcfH Is a Trimeric Thioredoxin-Like Bifunctional Enzyme with Both Thiol Oxidase and Disulfide Isomerase Activities

Subedi, Pramod, Paxman, Jason J., Wang, Geqing, Hor, Lilian, Hong, Yaoqin, Verderosa, Anthony D., Whitten, Andrew E., Panjikar, Santosh, Santos-Martin, Carlos F., Martin, Jennifer L., Totsika, Makrina and Heras, Begoña (2021). Salmonella enterica BcfH Is a Trimeric Thioredoxin-Like Bifunctional Enzyme with Both Thiol Oxidase and Disulfide Isomerase Activities. Antioxidants and Redox Signaling, 35 (1), 21-39. doi: 10.1089/ars.2020.8218

Antivirulence DsbA inhibitors attenuate Salmonella enterica serovar Typhimurium fitness without detectable resistance

Dhouib, Rabeb, Vagenas, Dimitrios, Hong, Yaoqin, Verderosa, Anthony D., Martin, Jennifer L., Heras, Begoña and Totsika, Makrina (2021). Antivirulence DsbA inhibitors attenuate Salmonella enterica serovar Typhimurium fitness without detectable resistance. FASEB BioAdvances, 3 (4), 231-242. doi: 10.1096/fba.2020-00100

A high-throughput cell-based assay pipeline for the preclinical development of bacterial DsbA inhibitors as antivirulence therapeutics

Verderosa, Anthony D., Dhouib, Rabeb, Hong, Yaoqin, Anderson, Taylah K., Heras, Begona and Totsika, Makrina (2021). A high-throughput cell-based assay pipeline for the preclinical development of bacterial DsbA inhibitors as antivirulence therapeutics. Scientific Reports, 11 (1) 1569. doi: 10.1038/s41598-021-81007-y

An in vitro reconstructed human skin equivalent model to study the role of skin integration around percutaneous devices against bacterial infection

Bolle, Eleonore C. L., Verderosa, Anthony D., Dhouib, Rabeb, Parker, Tony J., Fraser, John F., Dargaville, Tim R. and Totsika, Makrina (2020). An in vitro reconstructed human skin equivalent model to study the role of skin integration around percutaneous devices against bacterial infection. Frontiers in Microbiology, 11 670. doi: 10.3389/fmicb.2020.00670

Nitroxide functionalized antibiotics are promising eradication agents against Staphylococcus aureus biofilms

Verderosa, Anthony D., Dhouib, Rabeb, Fairfull-Smith, Kathryn E. and Totsika, Makrina (2020). Nitroxide functionalized antibiotics are promising eradication agents against Staphylococcus aureus biofilms. Antimicrobial Agents and Chemotherapy, 64 (1) e01685-19. doi: 10.1128/aac.01685-19

Bacterial biofilm eradication agents: a current review

Verderosa, Anthony D., Totsika, Makrina and Fairfull-Smith, Kathryn E. (2019). Bacterial biofilm eradication agents: a current review. Frontiers in Chemistry, 7 824. doi: 10.3389/fchem.2019.00824

Eradicating uropathogenic Escherichia coli biofilms with a ciprofloxacin-dinitroxide conjugate

Verderosa, Anthony D., Harris, Jessica, Dhouib, Rabeb, Totsika, Makrina and Fairfull-Smith, Kathryn E. (2019). Eradicating uropathogenic Escherichia coli biofilms with a ciprofloxacin-dinitroxide conjugate. MedChemComm, 10 (5), 699-711. doi: 10.1039/c9md00062c

Profluorescent fluoroquinolone- nitroxides for investigating antibiotic-bacterial interactions

Verderosa, Anthony D., Dhouib, Rabeb, Fairfull-Smith, Kathryn E. and Totsika, Makrina (2019). Profluorescent fluoroquinolone- nitroxides for investigating antibiotic-bacterial interactions. Antibiotics, 8 (1) 19, 19. doi: 10.3390/antibiotics8010019

Moraxella catarrhalis NucM is an entry nuclease involved in extracellular DNA and RNA degradation, cell competence and biofilm scaffolding

Tan, Aimee, Li, Wing-Sze, Verderosa, Anthony D., Blakeway, Luke V., D. Mubaiwa, Tsitsi, Totsika, Makrina and Seib, Kate L. (2019). Moraxella catarrhalis NucM is an entry nuclease involved in extracellular DNA and RNA degradation, cell competence and biofilm scaffolding. Scientific Reports, 9 (1) 2579. doi: 10.1038/s41598-019-39374-0

Ciprofloxacin-nitroxide hybrids with potential for biofilm control

Verderosa, Anthony D., de la Fuente-Núñez, César, Mansour, Sarah C., Cao, Jicong, Lu, Timothy K., Hancock, Robert E.W. and Fairfull-Smith, Kathryn E. (2017). Ciprofloxacin-nitroxide hybrids with potential for biofilm control. European Journal of Medicinal Chemistry, 138, 590-601. doi: 10.1016/j.ejmech.2017.06.058

Synthesis and evaluation of ciprofloxacin-nitroxide conjugates as anti-biofilm agents

Verderosa, Anthony D., Mansour, Sarah C., De La Fuente-Núñez, César, Hancock, Robert E. W. and Fairfull-Smith, Kathryn E. (2016). Synthesis and evaluation of ciprofloxacin-nitroxide conjugates as anti-biofilm agents. Molecules, 21 (7) 841. doi: 10.3390/molecules21070841