The University of Queensland

Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

Aguado, Julio, Amarilla, Alberto A., Taherian Fard, Atefeh, Albornoz, Eduardo A., Tyshkovskiy, Alexander, Schwabenland, Marius, Chaggar, Harman K., Modhiran, Naphak, Gómez-Inclán, Cecilia, Javed, Ibrahim, Baradar, Alireza A., Liang, Benjamin, Peng, Lianli, Dharmaratne, Malindrie, Pietrogrande, Giovanni, Padmanabhan, Pranesh, Freney, Morgan E., Parry, Rhys, Sng, Julian D. J., Isaacs, Ariel, Khromykh, Alexander A., Valenzuela Nieto, Guillermo, Rojas-Fernandez, Alejandro, Davis, Thomas P., Prinz, Marco, Bengsch, Bertram, Gladyshev, Vadim N., Woodruff, Trent M., Mar, Jessica C. ... Wolvetang, Ernst J. (2023). Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology. Nature Aging, 3 (12), 1-15. doi: 10.1038/s43587-023-00519-6

CRISPR-Cas9 direct fusions for improved genome editing via enhanced homologous recombination

Tabassum, Tahmina, Pietrogrande, Giovanni, Healy, Michael and Wolvetang, Ernst J. (2023). CRISPR-Cas9 direct fusions for improved genome editing via enhanced homologous recombination. International Journal of Molecular Sciences, 24 (19) 14701, 1-17. doi: 10.3390/ijms241914701

Deconstructing heterogeneity of replicative senescence in human mesenchymal stem cells at single cell resolution

Taherian Fard, Atefeh, Leeson, Hannah C., Aguado, Julio, Pietrogrande, Giovanni, Power, Dominique, Gómez-Inclán, Cecilia, Zheng, Huiwen, Nelson, Christopher B., Soheilmoghaddam, Farhad, Glass, Nick, Dharmaratne, Malindrie, Watson, Ebony R., Lu, Jennifer, Martin, Sally, Pickett, Hilda A., Cooper-White, Justin, Wolvetang, Ernst J. and Mar, Jessica C. (2023). Deconstructing heterogeneity of replicative senescence in human mesenchymal stem cells at single cell resolution. GeroScience, 46 (1), 1-17. doi: 10.1007/s11357-023-00829-y

Neural epidermal growth factor-like like protein 2 is expressed in human oligodendroglial cell types

Shaker, Mohammed R., Kahtan, Amna, Prasad, Renuka, Lee, Ju-Hyun, Pietrogrande, Giovanni, Leeson, Hannah C., Sun, Woong, Wolvetang, Ernst J. and Slonchak, Andrii (2022). Neural epidermal growth factor-like like protein 2 is expressed in human oligodendroglial cell types. Frontiers in Cell and Developmental Biology, 10 803061, 803061. doi: 10.3389/fcell.2022.803061

Corticosterone administration alters white matter tract structure and reduces gliosis in the sub-acute phase of experimental stroke

Zalewska, Katarzyna, Hood, Rebecca J., Pietrogrande, Giovanni, Sanchez-Bezanilla, Sonia, Ong, Lin Kooi, Johnson, Sarah J., Young, Kaylene M., Nilsson, Michael and Walker, Frederick R. (2021). Corticosterone administration alters white matter tract structure and reduces gliosis in the sub-acute phase of experimental stroke. International Journal of Molecular Sciences, 22 (13) 6693, 6693. doi: 10.3390/ijms22136693

Exploring how low oxygen post conditioning improves stroke-induced cognitive impairment: a consideration of amyloid-beta loading and other mechanisms

Zhao, Zidan, Hood, Rebecca J., Ong, Lin Kooi, Pietrogrande, Giovanni, Sanchez Bezanilla, Sonia, Warren, Kirby E., Ilicic, Marina, Kluge, Murielle G., TeBay, Clifford, Ottersen, Ole P., Johnson, Sarah J., Nilsson, Michael and Walker, Frederick R. (2021). Exploring how low oxygen post conditioning improves stroke-induced cognitive impairment: a consideration of amyloid-beta loading and other mechanisms. Frontiers in Neurology, 12 585189, 1-14. doi: 10.3389/fneur.2021.585189

Rapid and efficient generation of myelinating human oligodendrocytes in organoids

Shaker, Mohammed R., Pietrogrande, Giovanni, Martin, Sally, Lee, Ju-Hyun, Woong, Sun and Wolvetang, Ernst J. (2021). Rapid and efficient generation of myelinating human oligodendrocytes in organoids. Frontiers in Cellular Neuroscience, 15 631548, 1-11. doi: 10.3389/fncel.2021.631548

Low oxygen post conditioning as an efficient non-pharmacological strategy to promote motor function after stroke

Pietrogrande, Giovanni, Zalewska, Katarzyna, Zhao, Zidan, Johnson, Sarah J., Nilsson, Michael and Walker, Frederick R. (2018). Low oxygen post conditioning as an efficient non-pharmacological strategy to promote motor function after stroke. Translational Stroke Research, 10 (4), 402-412. doi: 10.1007/s12975-018-0656-5

Urokinase receptor promotes skin tumor formation by preventing epithelial cell activation of Notch1

Mazzieri, Roberta, Pietrogrande, Giovanni, Gerasi, Laura, Gandelli, Alessandro, Colombo, Piergiuseppe, Moi, Davide, Brombin, Chiara, Ambrosi, Alessandro, Danese, Silvio, Mignatti, Paolo, Blasi, Francesco and D'Alessio, Silvia (2015). Urokinase receptor promotes skin tumor formation by preventing epithelial cell activation of Notch1. Cancer Research, 75 (22), 4895-4909. doi: 10.1158/0008-5472.CAN-15-0378

VEGF-C-dependent stimulation of lymphatic function ameliorates experimental inflammatory bowel disease

D'Alessio, Silvia, Correale, Carmen, Tacconi, Carlotta, Gandelli, Alessandro, Pietrogrande, Giovanni, Vetrano, Stefania, Genua, Marco, Arena, Vincenzo, Spinelli, Antonino, Peyrin-Biroulet, Laurent, Fiocchi, Claudio and Danese, Silvio (2014). VEGF-C-dependent stimulation of lymphatic function ameliorates experimental inflammatory bowel disease. Journal of Clinical Investigation, 124 (9), 3863-3878. doi: 10.1172/JCI72189

Chemogenetic modulation of human in vitro motoneuron development accelerates maturation trajectory and electrophysical properties

Morrison, Sean, Shaker, Mohammed, Pietrogrande, Giovanni, Wolvetang, Ernst and Noakes, Peter (2023). Chemogenetic modulation of human in vitro motoneuron development accelerates maturation trajectory and electrophysical properties. ISN‐ESN 2023 Meeting, Porto, Portugal, 8‐11 August 2023. Chichester, West Sussex, United Kingdom: Wiley-Blackwell.