The University of Queensland

Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner

Willis, Emily F., MacDonald, Kelli P. A., Nguyen, Quan H., Garrido, Adahir Labrador, Gillespie, Ellen R., Harley, Samuel B. R., Bartlett, Perry F., Schroder, Wayne A., Yates, Abi G., Anthony, Daniel C., Rose-John, Stefan, Ruitenberg, Marc J. and Vukovic, Jana (2020). Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner. Cell, 180 (5), 833-846.e16. doi: 10.1016/j.cell.2020.02.013

ROCK2 regulates microglia proliferation and neuronal survival after traumatic brain injury

Willis, Emily F., Kim, Seung Jae, Chen, Wei, Nyuydzefe, Melanie, MacDonald, Kelli P.A., Zanin-Zhorov, Alexandra, Ruitenberg, Marc J. and Vukovic, Jana (2024). ROCK2 regulates microglia proliferation and neuronal survival after traumatic brain injury. Brain, Behavior, and Immunity, 117, 181-194. doi: 10.1016/j.bbi.2024.01.004

CSF-1R inhibitor PLX3397 attenuates peripheral and brain chronic GVHD and improves functional outcomes in mice

Shaikh, Samreen N., Willis, Emily F., Dierich, Max, Xu, Yi, Stuart, Samuel J. S., Gobe, Glenda C., Bashaw, Abate A., Rawashdeh, Oliver, Kim, Seung Jae and Vukovic, Jana (2023). CSF-1R inhibitor PLX3397 attenuates peripheral and brain chronic GVHD and improves functional outcomes in mice. Journal of Neuroinflammation, 20 (1) 300, 300. doi: 10.1186/s12974-023-02984-7

Robust mapping of spatiotemporal trajectories and cell–cell interactions in healthy and diseased tissues

Pham, Duy, Tan, Xiao, Balderson, Brad, Xu, Jun, Grice, Laura F., Yoon, Sohye, Willis, Emily F., Tran, Minh, Lam, Pui Yeng, Raghubar, Arti, Kalita-de Croft, Priyakshi, Lakhani, Sunil, Vukovic, Jana, Ruitenberg, Marc J. and Nguyen, Quan H. (2023). Robust mapping of spatiotemporal trajectories and cell–cell interactions in healthy and diseased tissues. Nature Communications, 14 (1) 7739, 1-25. doi: 10.1038/s41467-023-43120-6

Intravenous immunoglobulin (IVIG) promotes brain repair and improves cognitive outcomes after traumatic brain injury in a FcγRIIB receptor-dependent manner

Willis, Emily F., Gillespie, Ellen R., Guse, Kirsten, Zuercher, Adrian W., Käsermann, Fabian, Ruitenberg, Marc J. and Vukovic, Jana (2023). Intravenous immunoglobulin (IVIG) promotes brain repair and improves cognitive outcomes after traumatic brain injury in a FcγRIIB receptor-dependent manner. Brain, Behavior, and Immunity, 109, 37-50. doi: 10.1016/j.bbi.2022.12.018

Selective ablation of BDNF from microglia reveals novel roles in self-renewal and hippocampal neurogenesis

Harley, Samuel B. R., Willis, Emily F., Shaikh, Samreen N., Blackmore, Daniel G., Sah, Pankaj, Ruitenberg, Marc J., Bartlett, Perry F. and Vukovic, Jana (2021). Selective ablation of BDNF from microglia reveals novel roles in self-renewal and hippocampal neurogenesis. The Journal of Neuroscience, 41 (19), 4172-4186. doi: 10.1523/jneurosci.2539-20.2021

Protocol for brain-wide or region-specific microglia depletion and repopulation in adult mice

Willis, Emily F. and Vukovic, Jana (2020). Protocol for brain-wide or region-specific microglia depletion and repopulation in adult mice. STAR protocols, 1 (3) 100211, 100211. doi: 10.1016/j.xpro.2020.100211

Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner

Willis, Emily F., MacDonald, Kelli P. A., Nguyen, Quan H., Garrido, Adahir Labrador, Gillespie, Ellen R., Harley, Samuel B. R., Bartlett, Perry F., Schroder, Wayne A., Yates, Abi G., Anthony, Daniel C., Rose-John, Stefan, Ruitenberg, Marc J. and Vukovic, Jana (2020). Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner. Cell, 180 (5), 833-846.e16. doi: 10.1016/j.cell.2020.02.013

Complement components are upregulated and correlate with disease progression in the TDP-43 mouse model of amyotrophic lateral sclerosis

Lee, John D., Levin, Samantha C., Willis, Emily F., Li, Rui, Woodruff, Trent M. and Noakes, Peter G. (2018). Complement components are upregulated and correlate with disease progression in the TDP-43 mouse model of amyotrophic lateral sclerosis. Journal of Neuroinflammation, 15 (1) 171, 171. doi: 10.1186/s12974-018-1217-2

Defects in synaptic transmission at the neuromuscular junction precedes motor deficits in a TDP-43Q331K transgenic mouse model of amyotrophic lateral sclerosis

Chand, Kirat K., Lee, Kah Meng, Lee, John D., Qiu, Hao, Willis, Emily F., Lavidis, Nickolas A., Hilliard, Massimo A. and Noakes, Peter G. (2018). Defects in synaptic transmission at the neuromuscular junction precedes motor deficits in a TDP-43Q331K transgenic mouse model of amyotrophic lateral sclerosis. FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology, 32 (5), fj201700835R-2689. doi: 10.1096/fj.201700835R

Somatic Arc protein expression in hippocampal granule cells is increased in response to environmental change but independent of task-specific learning

Cleland, J. P., Willis, E. F., Bartlett, P. F. and Vukovic, J. (2017). Somatic Arc protein expression in hippocampal granule cells is increased in response to environmental change but independent of task-specific learning. Scientific Reports, 7 (1) 12477, 12477. doi: 10.1038/s41598-017-12583-1

Protocol for Short- and Longer-term Spatial Learning and Memory in Mice

Willis, Emily F., Bartlett, Perry F. and Vukovic, Jana (2017). Protocol for Short- and Longer-term Spatial Learning and Memory in Mice. Frontiers in Behavioral Neuroscience, 11 197, 1-8. doi: 10.3389/fnbeh.2017.00197

Role of microglia in traumatic brain injury

Willis, Emily (2020). Role of microglia in traumatic brain injury. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/906b939