The University of Queensland

AKT regulation of ORAI1-mediated calcium influx in breast cancer cells

Bong, Alice Hui Li, Hua, Trinh, So, Choon Leng, Peters, Amelia A., Robitaille, Mélanie, Tan, Yin Yi, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2022). AKT regulation of ORAI1-mediated calcium influx in breast cancer cells. Cancers, 14 (19) 4794, 1-14. doi: 10.3390/cancers14194794

ORAI1-regulated gene expression in breast cancer cells: Roles for STIM1 binding, calcium influx and transcription factor translocation

Robitaille, Mélanie, Chan, Shao Ming, Peters, Amelia A., Dai, Limin, So, Choon Leng, Bong, Alice H. L., Sadras, Francisco, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2022). ORAI1-regulated gene expression in breast cancer cells: Roles for STIM1 binding, calcium influx and transcription factor translocation. International Journal of Molecular Sciences, 23 (11) 5867, 1-14. doi: 10.3390/ijms23115867

ORAI1 regulates sustained cytosolic free calcium fluctuations during breast cancer cell apoptosis and apoptotic resistance via a STIM1 independent pathway

Bassett, John J., Robitaille, Mélanie, Peters, Amelia A., Bong, Alice H. L., Taing, Meng‐Wong, Wood, Ian A., Sadras, Francisco, Roberts‐Thomson, Sarah J. and Monteith, Gregory R. (2022). ORAI1 regulates sustained cytosolic free calcium fluctuations during breast cancer cell apoptosis and apoptotic resistance via a STIM1 independent pathway. The FASEB Journal, 36 (1) e22108, e22108. doi: 10.1096/fj.202002031rr

Assessment of doxorubicin-induced remodeling of Ca2+ signaling and associated Ca2+ regulating proteins in MDA-MB-231 breast cancer cells

Bong, Alice H.L., Bassett, John J., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2020). Assessment of doxorubicin-induced remodeling of Ca2+ signaling and associated Ca2+ regulating proteins in MDA-MB-231 breast cancer cells. Biochemical and Biophysical Research Communications, 522 (2), 532-538. doi: 10.1016/j.bbrc.2019.11.136

NCS-1 expression is higher in basal breast cancers and regulates calcium influx and cytotoxic responses to doxorubicin

Bong, Alice H. L., Robitaille, Mélanie, Milevskiy, Michael J. G., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2019). NCS-1 expression is higher in basal breast cancers and regulates calcium influx and cytotoxic responses to doxorubicin. Molecular Oncology, 14 (1) 1878-0261.12589, 87-104. doi: 10.1002/1878-0261.12589

Pharmacological inhibition of store-operated calcium entry in MDA-MB-468 basal A breast cancer cells: consequences on calcium signalling, cell migration and proliferation

Azimi, Iman, Bong, Alice H., Poo, Greta X. H., Armitage, Kaela, Lok, Dawn, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2018). Pharmacological inhibition of store-operated calcium entry in MDA-MB-468 basal A breast cancer cells: consequences on calcium signalling, cell migration and proliferation. Cellular and Molecular Life Sciences, 75 (24), 4525-4537. doi: 10.1007/s00018-018-2904-y

Calcium signaling and the therapeutic targeting of cancer cells

Bong, Alice H. L. and Monteith, Gregory R. (2018). Calcium signaling and the therapeutic targeting of cancer cells. Biochimica et Biophysica Acta, 1865 (11), 1786-1794. doi: 10.1016/j.bbamcr.2018.05.015

Assessment of cytosolic free calcium changes during ceramide-induced cell death in MDA-MB-231 breast cancer cells expressing the calcium sensor GCaMP6m

Bassett, John J., Bong, Alice H.L., Janke, Ellen K., Robitaille, Mélanie, Roberts-Thomson, Sarah J., Peters, Amelia A. and Monteith, Gregory R. (2018). Assessment of cytosolic free calcium changes during ceramide-induced cell death in MDA-MB-231 breast cancer cells expressing the calcium sensor GCaMP6m. Cell Calcium, 72, 39-50. doi: 10.1016/j.ceca.2018.02.003

Breast cancer cells: focus on the consequences of epithelial-to-mesenchymal transition

Bong, Alice H. L. and Monteith, Gregory R. (2017). Breast cancer cells: focus on the consequences of epithelial-to-mesenchymal transition. International Journal of Biochemistry & Cell Biology, 87 (33), 23-26. doi: 10.1016/j.biocel.2017.03.014

Abstract 3629: Calcium signalling and the breast cancer microenvironment

Bong, Alice H., Gieniec, Krystyna A., Sadras, Francisco, Robitaille, Mélanie, Roberts-Thomson, Sarah J., Davis, Felicity M. and Monteith, Gregory R. (2023). Abstract 3629: Calcium signalling and the breast cancer microenvironment. 114th Annual Meeting of the American Association for Cancer Research (AACR), Orlando, FL United States, 14-19 April 2023. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2023-3629

A recently identified ion channel in breast cancer

Bong, Alice H. L., Robitaille, Mélanie, Milevskiy, Michael J. G., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2019). A recently identified ion channel in breast cancer. AuPS/ASB Scientific meeting, Canberra, Australia, 1-4 December 2019.

Abstract P2-05-08: an assessment of the potential role of intracellular Ca2+store regulators in breast cancer cells

Bong, A.H., Roberts-Thomson, S.J., Milevskiy, M.J. and Monteith, G.R. (2019). Abstract P2-05-08: an assessment of the potential role of intracellular Ca2+store regulators in breast cancer cells. 2018 San Antonio Breast Cancer Symposium, San Antonio, TX, United States, 4-8 December 2018. Philadelphia, PA, United States: American Association for Cancer Research (AACR). doi: 10.1158/1538-7445.sabcs18-p2-05-08

The AKT activator SC79 promotes Ca2+ influx in MDA-MB-231 breast cancer cells

Tan, Yin Y., Bong, Alice H., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2018). The AKT activator SC79 promotes Ca2+ influx in MDA-MB-231 breast cancer cells. Australasian Society for Clinical and Experimental Pharmacologists and Toxicologists, Adelaide, SA, Australia, 27 - 30 November 2018.

Imaging intracellular Ca2+ dynamics in breast cancer using automated high-content fluorescence imaging

Bong, Alice, Bassett, John J, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2017). Imaging intracellular Ca2+ dynamics in breast cancer using automated high-content fluorescence imaging. SLAS2017, Washington, DC, United States, 4-8 February 2017.

Neuronal calcium sensor-1 (NCS-1) in the regulation of calcium homeostasis and cell death in MDA-MB-231 basal breast cancer cells

Bong, Alice H. L., Bassett, John J., Roberts-Thomson, Sarah J., Milevskiy, Michael J. G. and Monteith, Gregory R. (2017). Neuronal calcium sensor-1 (NCS-1) in the regulation of calcium homeostasis and cell death in MDA-MB-231 basal breast cancer cells. APSA-ASCEPT Joint Scientific Meeting, Brisbane, Australia, 5-8 December 2017.

Phosphatase and Tensin Homolog (PTEN) loss is associated with changes in Ca2+ signalling in MDA-MB-231 cells

Bong, Alice H.L., Hua, Trinh, Bassett, John J., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2017). Phosphatase and Tensin Homolog (PTEN) loss is associated with changes in Ca2+ signalling in MDA-MB-231 cells. 20th International Symposium on Calcium Binding Proteins and Calcium Function in Health and Disease, Awaji City, Japan, 22-26 October 2017.

Phosphatase and tensin homolog (PTEN) silencing suppresses Ca2+ responses in MDA-MB-231 breast cancer cells

Hua, Trin N., Bong, Alice H.L., Bassett, John J., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2017). Phosphatase and tensin homolog (PTEN) silencing suppresses Ca2+ responses in MDA-MB-231 breast cancer cells. APSA-ASCEPT Joint Scientific Meeting, Brisbane, QLD, Australia, 5-8 December 2017.

An Assessment of the effects of doxorubicin on calcium signalling in MDA-MB-231 breast cancer cells

Bong, Alice H. L., Bassett, John J., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2016). An Assessment of the effects of doxorubicin on calcium signalling in MDA-MB-231 breast cancer cells. ASCEPT-MPGPCR, Melbourne, Australia, 27–30 November 2016.

Changes in calcium signalling as a consequence of doxorubicin treatment in MDA-MB-231 breast cancer cells expressing a genetically-encoded calcium indicator

Bong, Alice H. I., Bassett, John J., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2016). Changes in calcium signalling as a consequence of doxorubicin treatment in MDA-MB-231 breast cancer cells expressing a genetically-encoded calcium indicator. 14th International Meeting of the European Calcium Society, Valladolid, Spain, 25-29 September 2016.

Assessment of the effects of genistein and resveratrol in an MDA-MB-231 breast cancer cell line expressing a genetically targeted calcium sensor.

Bong, Alice H. L., Bassett, John J., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2015). Assessment of the effects of genistein and resveratrol in an MDA-MB-231 breast cancer cell line expressing a genetically targeted calcium sensor.. APSA ASCEPT Joint Scientific Meeting 2015, Hobart, TAS, Australia, 29 November - 2 December 2015.