Insect-specific virus host restriction (2023–2025)

Abstract:
Mosquito-borne viruses are a topic of intense research due to their complex biology, ecology and evolution, and their potential to produce unpredictable outbreaks of disease in both humans and animals. Insect-specific viruses (ISVs) are viruses that replicate solely in mosquito cell and are unable to infect vertebrate tissues. This project aims to assess the biodiversity of ISVs in the Australian mosquito population and identify key factors behind their restriction in vertebrates. The objectives of the studies proposed will answer clearly defined important biological questions about ISVs, while also delivering technological advances, novel reagents and potential commercial outcomes for the control and prevention of arboviral disease.
Grant type:
ARC Discovery Early Career Researcher Award
Researchers:
  • ARC DECRA Fellow
    School of Chemistry and Molecular Biosciences
    Faculty of Science
    ARC DECRA Fellow
    School of Chemistry and Molecular Biosciences
    Faculty of Science
Funded by:
Australian Research Council