Mr Mark Chatfield


Centre for Health Services Research
Faculty of Medicine
+61 7 3346 5042


A/Prof Mark D. Chatfield is a diligent, highly experienced biostatistician. He is especially knowledgeable about clinical trials at UQ.

In collaboration with other researchers, he has published over 180 times in academic journals and has been/is an investigator on 26 NHMRC/MRFF funded (>$49M) studies (mostly clinical trials). He has co-supervised 4 PhD students to completion, and is currently an advisor to 5 PhD students.

He is regularly invited to be a statistical collaborator, advisor or consultant by researchers in the Faculty of Medicine and the Faculty of Health and Behavioural Sciences.

In 2021, he won a Service Excellence Award for outstanding biostatistical support and collaboration with numerous Faculty researchers. He is the leading biostatistician in the Research and Statistical Support Service (RASSS). In 2020, he was awarded The Outstanding Mid-Career Researcher by the Centre for Health Services Research.

He is an Honorary Fellow (Associate Professor, 2016-present) with Menzies School of Health Research, where he worked 2012-2017. He has also worked at QIMR Berghofer Medical Research Institute (2017-2018), NHMRC Clinical Trials Centre, University of Sydney (2009-2012), UK MRC Human Nutrition Research (2006-2009), Department of Public Health and Primary Care, University of Cambridge (2002-2006).

Research Interests

  • Randomised Clinical/Controlled Trials (RCTs)
    I make significant contributions to funding applications, trial design, monitoring, analysis, presentation and interpretation. I have substantial involvement with trials of various designs, and have a good understanding of adaptive trials. I have been involved with methodological research into cluster randomised trials (ICC for binary outcomes), sample size, width of 95% CI. I am a member of the Australian Clinical Trials Alliance (ACTA) Statistics in Trials Interest Group (STInG) executive committee. I have judged ACTA's Excellence in Trial Statistics Award in recent years. I have been a NHMRC & MRFF trials grant review panel member. I have given talks on the statistical aspects of trials.
  • Log scales, and the interpretation of natural log scale ouput
    I am currently thinking deeply about symmetric percentage differences: e.g. 100(A-B)/0.5(A+B)% and 100(lnA-lnB)%, Bland-Altman plots, summarising and plotting lognormal data, and the immediate interpretation of parameters on the natural log scale.
  • Meta analysis
    While involved with different types of meta-analysis, I am especially interested in the meta-analysis of continuous outcomes from RCTs. I have taught meta-analysis in RevMan and Stata. I am a member of the Cochrane Statistical Methods Group.
  • Other stats
    I am a member of the Royal Statistical Society (2002-present). I have reviewed many articles for The Lancet, and other journals. I have taught regression modelling.
  • Stata statistical software
    I am a Stata expert, and have contributed several programs ( (1) table1_mc ... creates "table 1" of baseline characteristics, (2) blandaltman... creates Bland-Altman plots featuring differences or %differences or ratios, (3) box_logscale... creates box plots on the log scale (generalising Tukey’s definition of whiskers), (4) power tworates_zhu... calculates sample size or power for a two-sample test of rates, (5) ciwidth proportions_mc... calculates precision and power for a CI-based comparison of two independent proportions (RD, RR, or OR), (6) precombine... examines n ≥ 2 datasets before combining, (7) labeldatasyntax... produces syntax to label variables and values given a data dictionary, (8) skilmack... performs the Skillings-Mack test, (9) tolerance... calculates tolerance intervals (normal distribution).


  • Masters (Coursework), University of Oxford
  • Masters (Coursework), University of Southampton
  • Bachelor of Arts, University of Oxford


View all Publications


  • Doctor Philosophy

  • Doctor Philosophy

  • Doctor Philosophy

View all Supervision


Featured Publications

Book Chapter

  • Fleming, Jane, Matthews, Fiona E., Chatfield, Mark and Brayne, Carol (2006). Population levels of mild cognitive impairment in England and Wales. Mild Cognitive Impairment: International Perspectives. (pp. 77-91) edited by Holly A. Tuokko and David F. Hultsch. New York, NY, United States: Taylor and Francis. doi: 10.4324/9780203782996

Journal Article

Conference Publication

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

Completed Supervision