Honorary Senior Fellow
Overview
I completed a PhD in Neuroscience with Jack Pettigrew (FRS) at Vision, Touch & Hearing Research Centre followed by an NHMRC Clinical Research Fellowship at Alfred Health & Monash University.
Back in QLD I'm continuing a transdisciplinary research & innovation program to Bring Discoveries of the Brain to Life!
I'm currently focused on developing novel MedTech Biotech diagnostics & therapeutics for enhancing human performance, recovery & resilience with the following projects:
[1] Precision Pain Medicine — the largest genetic study of persistent (chronic) pain in Australia, in collaboration with QIMR Berghofer & Monash University, aims to identify pharmacogenomics causal pathways for the design of personalised therapeutics & effective early intervention approaches (e.g., screening, education, prevention).
[2] Brain Switcha — A digital transdiagnostic biomarker and cloud-based large-scale population phenotyping & analytics platform to improve early intervention strategies in sleep & mental health conditions (esp. at-risk youth cohorts) and recruitment screening for Defence forces.
[3] VCS — vestibulocortical stimulation: A simple, inexpensive, non-invasive & non-pharmacologic neurotherapeutic treatment technique for fibromyalgia (with US colleagues) and other centralised pain syndromes, sleep apnoea, dementia & mental health conditions (e.g., depression, PTSD, bipolar disorder).
I also have >5 years professional services experience providing specialist research performance evaluation, consultation, reporting & training workshops that successfully delivered several major strategic priorities to a large internal & external client base — such as organisational unit leaders/managers at multiple levels (e.g., Centre/Department) and senior executive business missions for national/international strategic partnerships. This work includes mapping, monitoring & benchmarking of research capacity, capabilities/strengths, gaps & collaboration networks (e.g., clinical, corporate & government) across diverse disciplines for Annual & Septennial Departmental Reviews (e.g., patent, policy & clinical guideline citations; external stakeholder engagement including media); ARC Engagement & Impact assessments; and workforce capability development (e.g., recruitment for senior leadership positions and ranking of NHMRC/ARC funding applicants).
In particular, I enjoy meeting & connecting people with a shared vision & commitment towards building innovative & sustainable public-private partnerships to deliver meaningful solutions for the wider community.
Research Interests
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VCS — Vestibulocortical Stimulation: Applications & mechanisms
— effectiveness of non-invasive vestibular neuromodulation protocols as a treatment for psychiatric & neurological illnesses (e.g., depression, bipolar disorder, post-traumatic stress disorder, dementia, epilepsy, persistent pain) and enhancing affective-cognitive Resilience in Contested Environments #RiCE | #PrecisionPainMedicine — clinical and performance-enhancing applications of repeated VCS (#rVCS) — and the genetics & neuroimaging of its (therapeutic) response — with the aim of elucidating novel electroceutical pathways, response biomarkers and personalised treatment protocols across a spectrum psychiatric & neurological disorders | 'Electroceutomics' -
Minimal phenotyping: Perceptual & cognitive biomarkers
— validating the clinical utility of novel visual task measures for identifying individuals at increased risk of developing mental illness (e.g., young people, at-risk/early psychosis cohorts). — multi-platform development of candidate diagnostic/endophenotype perceptual & cognitive task measures for large-scale user-friendly testing in genotyped and at-risk/youth cohorts (e.g., web, mobile, tablet, gaming, virtual reality). -
Phylogenetics & evolution of bistable switching and VCS network
— from bacterial chemotaxis & fruit fly optomotor responses to binary decision-making in mammals (e.g., approach/avoidance choice behaviour) and disordered mood/cognitive states in humans (e.g., mania/depression, denial/insight) — investigating the comparative genetics, neural network dynamics (e.g., vestibulocortical circuitry) and molecular mechanisms of bistable (anti-phase) interhemispheric oscillations — which have been observed across a range of phenotypes (e.g., biological rhythms, autonomic functions, oculomotor activity, perception/attention, cognitive/behaviour changes) and in different species (e.g., Drosophila, sandlance, birds, cetaceans, rodents, humans) | #PrecisionSwitchMedicine -
MedTech & Biotech platform development
— autonomic activity recording devices with real-time analysis output of endogenous rhythms and their clinical (diagnostic) utility in psychiatry, neurology & sleep medicine | #PrecisionSleepMedicine — portable/wearable devices with integrated software applications for (i) perceptual rivalry viewing (e.g., stereoscopic 3D displays), data collection & analyses; (ii) probing interhemispheric rhythms (e.g., autonomic respiratory/nasal cycle periodicity); and (iii) inducing, recording & real-time analysis output of VCS. -
Scientometrics of research benefits
— developing quantitative indicators of interdisciplinary conceptual & empirical synthesis, scientific impact, translational & innovation outcomes using machine learning (A.I.) analytical methods.
Qualifications
- Doctor of Philosophy, The University of Queensland
- Bachelor (Honours), The University of Queensland
- Bachelor of Arts, The University of Queensland
Publications
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Journal Article: Dichoptic viewing methods for binocular rivalry research: prospects for large-scale clinical and genetic studies
Law, Phillip C. F., Paton, Bryan K., Thomson, Richard H., Liu, Guang B., Miller, Steven M. and Ngo, Trung T. (2013). Dichoptic viewing methods for binocular rivalry research: prospects for large-scale clinical and genetic studies. Twin Research and Human Genetics, 16 (6), 1033-1078. doi: 10.1017/thg.2013.76
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Book Chapter: Binocular rivalry, brain stimulation and bipolar disorder
Ngo, Trung T., Barsdell, Wendy N., Law, Phillip C. F. and Miller, Steven M. (2013). Binocular rivalry, brain stimulation and bipolar disorder. The constitution of visual consciousness: Lessons from binocular rivalry. (pp. 211-252) edited by S. M. Miller. Amsterdam, The Netherlands: John Benjamins Publishing Company. doi: 10.1075/aicr.90.09ngo
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Book Chapter: Early views on binocular rivalry
Wade, Nicholas J. and Ngo, Trung T. (2013). Early views on binocular rivalry. The constitution of visual consciousness: Lessons from binocular rivalry. (pp. 77-108) edited by S. M. Miller. Amsterdam, The Netherlands: John Benjamins Publishing Company. doi: 10.1075/aicr.90.04wad
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Journal Article: Psychiatric and genetic studies of binocular rivalry: an endophenotype for bipolar disorder?
Ngo, Trung T., Mitchell, Philip B., Martin, Nicholas G. and Miller, Steven M. (2011). Psychiatric and genetic studies of binocular rivalry: an endophenotype for bipolar disorder?. Acta Neuropsychiatrica, 23 (1), 37-42. doi: 10.1111/j.1601-5215.2010.00510.x
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Journal Article: Caloric vestibular stimulation reveals discrete neural mechanisms for coherence rivalry and eye rivalry: A meta-rivalry model
Ngo, Trung T., Liu, Guang B., Tilley, Andrew J., Pettigrew, John D. and Miller, Steven M. (2007). Caloric vestibular stimulation reveals discrete neural mechanisms for coherence rivalry and eye rivalry: A meta-rivalry model. Vision Research, 47 (21), 2685-2699. doi: 10.1016/j.visres.2007.03.024
Available Projects
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Honours / Masters / PhD / DPsych / DBiotech / MBBS / MD research projects
The following research projects are open to enthusiastic & driven individuals from a wide range of background disciplines/industry experience, e.g., biomedical/electrical engineering, physics, computer science, mathematics & statistics, biological/life sciences, medicine & allied health, information technology, psychology:
Minimal phenotyping: Perceptual & cognitive biomarkers
- validating the clinical utility of novel visual task measures for identifying individuals at increased risk of developing mental illness (e.g., young people, at-risk/early psychosis cohorts).
- multi-platform development of candidate diagnostic/endophenotype perceptual & cognitive task measures for large-scale user-friendly testing in genotyped and at-risk/youth cohorts (e.g., web, mobile, tablet, gaming, virtual reality).
VCS — VestibuloCortical Stimulation: Applications & mechanisms
- effectiveness of non-invasive vestibular neuromodulation protocols as a treatment for psychiatric & neurological illnesses (e.g., depression, bipolar disorder, post-traumatic stress disorder, dementia, epilepsy, persistent pain) and enhancing affective-cognitive Resilience in Contested Environments #RiCE | #PrecisionPainMedicine
- clinical and performance-enhancing applications of repeated VCS (#rVCS) — and the genetics & neuroimaging of its (therapeutic) response — with the aim of elucidating novel electroceutical pathways, response biomarkers and personalised treatment protocols across a spectrum psychiatric & neurological disorders | 'Electroceutomics'
MedTech & Biotech platform development
- autonomic activity recording devices with real-time analysis output of endogenous rhythms and their clinical (diagnostic) utility in psychiatry, neurology & sleep medicine | #PrecisionSleepMedicine
- portable/wearable devices with integrated software applications for (i) perceptual rivalry viewing (e.g., stereoscopic 3D displays), data collection & analyses; (ii) probing interhemispheric rhythms (e.g., autonomic respiratory/nasal cycle periodicity); and (iii) inducing, recording & real-time analysis output of VCS.
Phylogenetics & evolution of bistable switching and VCS network
- from bacterial chemotaxis & fruit fly optomotor responses to binary decision-making in mammals (e.g., approach/avoidance choice behaviour) and disordered mood/cognitive states in humans (e.g., mania/depression, denial/insight)
- investigating the comparative genetics, neural network dynamics (e.g., vestibulocortical circuitry) and molecular mechanisms of bistable (anti-phase) interhemispheric oscillations — which have been observed across a range of phenotypes (e.g., biological rhythms, autonomic functions, oculomotor activity, perception/attention, cognitive/behaviour changes) and in different species (e.g., Drosophila, sandlance, birds, cetaceans, rodents, humans) | #PrecisionSwitchMedicine
Scientometrics of research benefits
- developing quantitative indicators of interdisciplinary conceptual & empirical synthesis, scientific impact, translational & innovation outcomes using machine learning (A.I.) analytical methods.
Publications
Featured Publications
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Law, Phillip C. F., Paton, Bryan K., Thomson, Richard H., Liu, Guang B., Miller, Steven M. and Ngo, Trung T. (2013). Dichoptic viewing methods for binocular rivalry research: prospects for large-scale clinical and genetic studies. Twin Research and Human Genetics, 16 (6), 1033-1078. doi: 10.1017/thg.2013.76
-
Binocular rivalry, brain stimulation and bipolar disorder
Ngo, Trung T., Barsdell, Wendy N., Law, Phillip C. F. and Miller, Steven M. (2013). Binocular rivalry, brain stimulation and bipolar disorder. The constitution of visual consciousness: Lessons from binocular rivalry. (pp. 211-252) edited by S. M. Miller. Amsterdam, The Netherlands: John Benjamins Publishing Company. doi: 10.1075/aicr.90.09ngo
-
Early views on binocular rivalry
Wade, Nicholas J. and Ngo, Trung T. (2013). Early views on binocular rivalry. The constitution of visual consciousness: Lessons from binocular rivalry. (pp. 77-108) edited by S. M. Miller. Amsterdam, The Netherlands: John Benjamins Publishing Company. doi: 10.1075/aicr.90.04wad
-
Psychiatric and genetic studies of binocular rivalry: an endophenotype for bipolar disorder?
Ngo, Trung T., Mitchell, Philip B., Martin, Nicholas G. and Miller, Steven M. (2011). Psychiatric and genetic studies of binocular rivalry: an endophenotype for bipolar disorder?. Acta Neuropsychiatrica, 23 (1), 37-42. doi: 10.1111/j.1601-5215.2010.00510.x
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Ngo, Trung T., Liu, Guang B., Tilley, Andrew J., Pettigrew, John D. and Miller, Steven M. (2007). Caloric vestibular stimulation reveals discrete neural mechanisms for coherence rivalry and eye rivalry: A meta-rivalry model. Vision Research, 47 (21), 2685-2699. doi: 10.1016/j.visres.2007.03.024
Book Chapter
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Binocular rivalry, brain stimulation and bipolar disorder
Ngo, Trung T., Barsdell, Wendy N., Law, Phillip C. F. and Miller, Steven M. (2013). Binocular rivalry, brain stimulation and bipolar disorder. The constitution of visual consciousness: Lessons from binocular rivalry. (pp. 211-252) edited by S. M. Miller. Amsterdam, The Netherlands: John Benjamins Publishing Company. doi: 10.1075/aicr.90.09ngo
-
Early views on binocular rivalry
Wade, Nicholas J. and Ngo, Trung T. (2013). Early views on binocular rivalry. The constitution of visual consciousness: Lessons from binocular rivalry. (pp. 77-108) edited by S. M. Miller. Amsterdam, The Netherlands: John Benjamins Publishing Company. doi: 10.1075/aicr.90.04wad
Journal Article
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Kaplan, Michael H, Zhou, Celine H, Carroll, Emily, Weinberg, Alan D, Clauw, Daniel J, Ngô, Trung Thành and Tassiulas, Ioannis (2023). Pain Relief in Refractory Fibromyalgia Following Vestibulocortical Stimulation: An Open-label Pilot Trial. Pain Medicine. doi: 10.1093/pm/pnad145
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Genetic impact of blood C-reactive protein levels on chronic spinal and widespread pain
Farrell, Scott F., Sterling, Michele, Klyne, David M., Mustafa, Sanam, Campos, Adrián I., Kho, Pik-Fang, Lundberg, Mischa, Rentería, Miguel E., Ngo, Trung Thanh and Cuéllar-Partida, Gabriel (2023). Genetic impact of blood C-reactive protein levels on chronic spinal and widespread pain. European Spine Journal, 32 (6), 2078-2085. doi: 10.1007/s00586-023-07711-7
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Farrell, Scott F., Kho, Pik-Fang, Lundberg, Mischa, Campos, Adrián I., Rentería, Miguel E., de Zoete, Rutger M.J., Sterling, Michele, Ngo, Trung Thanh and Cuéllar-Partida, Gabriel (2023). A shared genetic signature for common chronic pain conditions and its impact on biopsychosocial traits. The Journal of Pain, 24 (3), 369-386. doi: 10.1016/j.jpain.2022.10.005
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Genetic basis to structural grey matter associations with chronic pain
Farrell, Scott F, Campos, Adrián I, Kho, Pik-Fang, de Zoete, Rutger M J, Sterling, Michele, Rentería, Miguel E, Ngo, Trung Thanh and Cuéllar-Partida, Gabriel (2021). Genetic basis to structural grey matter associations with chronic pain. Brain, 144 (12), 3611-3622. doi: 10.1093/brain/awab334
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Campos, Adrián I., Ngo, Trung Thanh, Medland, Sarah E., Wray, Naomi R., Hickie, Ian B., Byrne, Enda M., Martin, Nicholas G. and Rentería, Miguel E. (2021). Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtype. Australian and New Zealand Journal of Psychiatry, 56 (9) ARTN 00048674211031491, 1-10. doi: 10.1177/00048674211031491
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Roughan, William H., Campos, Adrián I., García-Marín, Luis M., Cuéllar-Partida, Gabriel, Lupton, Michelle K., Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Byrne, Enda M., Ngo, Trung Thanh, Martin, Nicholas G. and Rentería, Miguel E. (2021). Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness. Frontiers in Psychiatry, 12 643609, 1-13. doi: 10.3389/fpsyt.2021.643609
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Tolerability of caloric vestibular stimulation in a persistent pain cohort
Ngo, Trung T., Barsdell, Wendy N., Law, Phillip C.F., Arnold, Carolyn A., Chou, Michael J., Nunn, Andrew K., Brown, Douglas J., Fitzgerald, Paul B., Gibson, Stephen J. and Miller, Steven M. (2020). Tolerability of caloric vestibular stimulation in a persistent pain cohort. Brain Stimulation, 13 (5), 1446-1448. doi: 10.1016/j.brs.2020.07.003
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An update on adjunctive treatment options for bipolar disorder
Dean, Olivia M., Gliddon, Emma, Van Rheenen, Tamsyn E., Giorlando, Francesco, Davidson, Sandra K., Kaur, Manreena, Ngo, Trung T. and Williams, Lana J. (2018). An update on adjunctive treatment options for bipolar disorder. Bipolar Disorders, 20 (2), 87-96. doi: 10.1111/bdi.12601
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Law, Phillip C. F., Gurvich, Caroline T., Ngo, Trung T. and Miller, Steven M. (2017). Evidence that eye-movement profiles do not explain slow binocular rivalry rate in bipolar disorder: support for a perceptual endophenotype. Bipolar Disorders, 19 (6), 465-476. doi: 10.1111/bdi.12515
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Law, Phillip C. F., Miller, Steven M. and Ngo, Trung T. (2017). The effect of stimulus strength on binocular rivalry rate in healthy individuals: Implications for genetic, clinical and individual differences studies. Physiology & Behavior, 181, 127-136. doi: 10.1016/j.physbeh.2017.08.023
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Law, Phillip C. F., Paton, Bryan K., Riddiford, Jacqueline A., Gurvich, Caroline T., Ngo, Trung T. and Miller, Steven M. (2015). No relationship between binocular rivalry rate and eye-movement profiles in healthy individuals: a Bayes factor analysis. Perception, 44 (6), 643-661. doi: 10.1177/0301006615594267
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Law, Phillip C. F., Paton, Bryan K., Thomson, Richard H., Liu, Guang B., Miller, Steven M. and Ngo, Trung T. (2013). Dichoptic viewing methods for binocular rivalry research: prospects for large-scale clinical and genetic studies. Twin Research and Human Genetics, 16 (6), 1033-1078. doi: 10.1017/thg.2013.76
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Individual differences in moral behaviour: a role for response to risk and uncertainty?
Palmer, Colin J., Paton, Bryan, Ngo, Trung T., Thomson, Richard H., Hohwy, Jakob and Miller, Steven M. (2013). Individual differences in moral behaviour: a role for response to risk and uncertainty?. Neuroethics, 6 (1), 97-103. doi: 10.1007/s12152-012-9158-4
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Attentional switching in humans and flies: rivalry in large and miniature brains
Miller, Steven Mark, Ngo, Trung Thanh and van Swinderen, Bruno (2012). Attentional switching in humans and flies: rivalry in large and miniature brains. Frontiers in Human Neuroscience, 5 (JANUARY 2012), 1-17. doi: 10.3389/fnhum.2011.00188
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Psychiatric and genetic studies of binocular rivalry: an endophenotype for bipolar disorder?
Ngo, Trung T., Mitchell, Philip B., Martin, Nicholas G. and Miller, Steven M. (2011). Psychiatric and genetic studies of binocular rivalry: an endophenotype for bipolar disorder?. Acta Neuropsychiatrica, 23 (1), 37-42. doi: 10.1111/j.1601-5215.2010.00510.x
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Genetic contribution to individual variation in binocular rivalry rate
Miller, Steven M., Hansell, Narelle K., Ngo, Trung T., Liu, Guang B., Pettigrew, John D., Martin, Nicholas G. and Wright, Margaret J. (2010). Genetic contribution to individual variation in binocular rivalry rate. Proceedings of the National Academy of Sciences of the United States of America, 107 (6), 2664-2668. doi: 10.1073/pnas.0912149107
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The changing face of perceptual rivalry
Ngo, T. T., Liu, G. B., Tilley, A. J., Pettigrew, J. D. and Miller, S. M. (2007). The changing face of perceptual rivalry. Brain Research Bulletin, 75 (5), 610-618. doi: 10.1016/j.brainresbull.2007.10.006
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Ngo, Trung T., Liu, Guang B., Tilley, Andrew J., Pettigrew, John D. and Miller, Steven M. (2007). Caloric vestibular stimulation reveals discrete neural mechanisms for coherence rivalry and eye rivalry: A meta-rivalry model. Vision Research, 47 (21), 2685-2699. doi: 10.1016/j.visres.2007.03.024
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Miller, Steven M. and Ngo, Trung T. (2007). Studies of caloric vestibular stimulation: implications for the cognitive neurosciences, the clinical neurosciences and neurophilosophy. Acta Neuropsychiatrica, 19 (3), 183-203. doi: 10.1111/j.1601-5215.2007.00208.x
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The use of tDCS and CVS as methods of non-invasive brain stimulation
Been, Gregory, Ngo, Trung T., Miller, Steven M. and Fitzgerald, Paul B. (2007). The use of tDCS and CVS as methods of non-invasive brain stimulation. Brain Research Reviews, 56 (2), 346-361. doi: 10.1016/j.brainresrev.2007.08.001
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Slow binocular rivalry in bipolar disorder
Miller, S.M., Gynther, B.D., Heslop, K.R., Liu, G.B., Mitchell, P.B., Ngo, T.T., Pettigrew, J.D. and Geffen, L.B. (2003). Slow binocular rivalry in bipolar disorder. Psychological Medicine, 33 (4), 683-692. doi: 10.1017/S0033291703007475
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Binocular rivalry and perceptual coherence
Ngo, T. T., Miller, S. M., Liu, G. B. and Pettigrew, J. D. (2000). Binocular rivalry and perceptual coherence. Current Biology, 10 (4), R134-R136. doi: 10.1016/S0960-9822(00)00399-7
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Interhemispheric switching mediates perceptual rivalry
Miller, SM, Liu, GB, Ngo, TT, Hooper, G, Riek, S, Carson, RG and Pettigrew, JD (2000). Interhemispheric switching mediates perceptual rivalry. Current Biology, 10 (7), 383-392. doi: 10.1016/S0960-9822(00)00416-4
Conference Publication
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Campos, Adrián I., Roughan, William H., García-Marin, Luis M., Cuéllar-Partida, Gabriel, Lupton, Michelle K., Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Byrne, Enda M., Ngo, Trung T., Martin, Nicholas G. and Rentería, Miguel E. (2020). The relationship between comorbid chronic pain and poorer self-reported antidepressant efficacy is partly mediated by genetics. Virtual 2020 World Congress of Psychiatric Genetics (WCPG), Online, 16–22 October 2020.
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Ngo, Trung Thanh, Zhu, Guohun, Rentería, Miguel E. and Cuéllar-Partida, Gabriel (2020). Elucidating a phylogenetic switching model of sleep, vision & mental health with computational biology and complex network analyses. Systems & Computational Neuroscience Down Under (SCiNDU) 2020 meeting, St Lucia, QLD Australia, 29–31 January 2020.
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Genetic, lifestyle and environmental risk factors for chronic pain revealed through GWAS
Lundberg, Mischa, Campos, Adrian I., Farrell, Scott F., Wang, Geng, Sterling, Michele M., Rentería, Miguel E., Ngo, Trung Thanh and Cuéllar-Partida, Gabriel (2020). Genetic, lifestyle and environmental risk factors for chronic pain revealed through GWAS. 50th Annual Meeting of the Behavior Genetics Association, Online, 26 June 2020. NEW YORK: SPRINGER.
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A genome-wide association study (GWAS) of chronic pain
Lundberg, Mischa, Campos-González, Adrian I., Rentería, Miguel E., Ngo, Trung Thanh and Cuéllar-Partida, Gabriel (2019). A genome-wide association study (GWAS) of chronic pain. Brisbane Pain Research Symposium 2019: Multidisciplinary Perspectives & Therapeutics, St Lucia. QLD, Australia, 29 November 2019.
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A phylogenetic switch model of brain and behavior: From E. coli to e-Mental Health applications
Ngo, Trung Thanh (2019). A phylogenetic switch model of brain and behavior: From E. coli to e-Mental Health applications. Memorial Celebration of Emeritus Professor Jack Pettigrew’s Life in Science, St Lucia, QLD Australia, 18 October 2019.
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Complex-Traits Genetics Virtual Lab: A community-driven web platform for post-GWAS analyses
Cuéllar-Partida, Gabriel, Lundberg, Mischa, Campos-González, Adrian I., Kho, Pik Fang, D’Urso, Shannon, Hwang, Liang-Dar, Ngo, Trung Thanh and Rentería, Miguel E. (2019). Complex-Traits Genetics Virtual Lab: A community-driven web platform for post-GWAS analyses. American Society of Human Genetics (ASHG) 69th Annual Meeting, Houston, TX United States, 15–19 October 2019.
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Lundberg, Mischa, Campos, Adrian, Rentería, Miguel E., Ngo, Trung Thanh and Cuéllar-Partida, Gabriel (2019). Dissecting the genetic architecture of chronic pain using CTG-VL — Complex-Traits Genetics Virtual Lab. PAH Health Symposium & Translational Research Symposium, Woolloongabba Brisbane, QLD Australia, 5–6 Aug 2019.
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Lundberg, Mischa, Campos, Adrian, Rentería, Miguel, Ngo, Trung and Cuéllar-Partida, Gabriel (2019). Dissecting the genetic architecture of chronic pain using CTG-VL — Complex-Traits Genetics Virtual Lab. 49th Annual Meeting of the Behavior Genetics Association, Stockholm, Sweden, 26–29 June 2019. New York, NY United States: Springer Nature. doi: 10.1007/s10519-019-09973-8
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Genetic epidemiology of back pain: Examining causality with Complex Traits Virtual Lab
Ngo, Trung Thanh, Lundberg, Mischa, Campos-González, Adrian, Kho, Pik Fang, D’Urso, Shannon, Hwang, Liang-Dar, Rentería, Miguel and Cuéllar-Partida, Gabriel (2019). Genetic epidemiology of back pain: Examining causality with Complex Traits Virtual Lab. Australasian Epidemiological Association 2019 Annual Scientific Meeting — 'Epidemiology in the real world', South Brisbane, QLD Australia, 23–25 October 2019.
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Ngo, Trung T. and Johnson, Jeremy C. S. (2019). Non-invasive therapeutic intervention for impaired insight in psychiatric disorders: a repeated vestibulocortical stimulation (rVCS) study protocol. Asian Federation of Psychiatric Associations 7th World Congress of Asian Psychiatry, Sydney, NSW, Australia, 21–24 February 2019.
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Ngo, Trung T. , Rentería, Miguel E. and Cuéllar-Partida, Gabriel (2019). Precision switch medicine: transdiagnostic stratification of bipolar and related disorders with an integrated phenotyping and genetics analysis cloud platform. 21st Annual ISBD Conference: Global Advances in Bipolar Disorder and Depression, International Convention Centre, Sydney, Australia, 20–23 March 2019. Hoboken, NJ, United States: Wiley-Blackwell. doi: 10.1111/bdi.12746
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Campos-González, Adrian, Cuéllar-Partida, Gabriel, Rentería, Miguel and Ngo, Trung (2019). Towards precision pain medicine: Characterising persistent pain and its underlying genetics in 288,118 adults. International Neuromodulation Society’s 14th World Congress, ICC Sydney, NSW Australia, 25–30 May 2019. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1111/ner.12958
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Cuéllar-Partida, Gabriel, Kho, Pik Fang and Ngo, Trung Thanh (2019). Unlocking your genes for analysis: An open science web platform for research discovery, replication and translation. AIMOS 2019 conference (Association for Interdisciplinary Meta-research & Open Science), Melbourne, VIC, Australia, 7–8 November 2019.
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Ngo, Trung T. , Rentería, Miguel E. and Cuéllar-Partida, Gabriel (2018). Advancing a neurogenomics oscillator model of bistable affective-cognitive states, behaviour and disorders. 5th Annual Australasian Society for Social & Affective Neuroscience Conference, Brisbane QLD, Australia, 20–21 June 2018.
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Trung T. Ngo and Gabriel Cuéllar-Partida (2018). Bistable visual perception and switching behaviour: investigating a fundamental brain mechanism with computational biology methods. International Congress of Neuroethology, Brisbane Convention & Exhibition Centre, 15–20 July 2018. International Society for Neuroethology.
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Characterising a putative EEG switching biomarker in chronobiology
Zhu, G. and Ngo, T. (2018). Characterising a putative EEG switching biomarker in chronobiology. 30th Annual Scientific Meeting (ASM) of Australasian-Sleep-Association and the Australasian-Sleep-Technologists-Association (Sleep DownUnder), Brisbane Australia, 17-20 October 2018. Hoboken, NJ United States: Wiley.
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Complex network signal analysis of sleep EEG: brain switching dynamics and potential applications
Zhu, Guohun and Ngo, Trung T. (2018). Complex network signal analysis of sleep EEG: brain switching dynamics and potential applications. 11th Australasian Workshop on Neuro-Engineering & Computational Neuroscience, University of Sydney, NSW, Australia, 27–29 November 2018.
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Ngo, Trung T. , Rentería, Miguel E. and Cuéllar-Partida, Gabriel (2018). E-mental health transdiagnostic stratification: A cloud-based platform for multi-phenotyping and genetic analyses. 40th Annual Society for Mental Health Research Conference, Noosa Heads, QLD Australia, 28–30 November 2018.
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Zhang, Zhimin , Ertekin, Deniz , Zhu, Guohun and Ngo, Trung T. (2018). EEG brain switching activity in sleep apnoea: examining a putative chronobiological marker with fuzzy entropy. 38th Australasian Neuroscience Society Annual Scientific Meeting, Brisbane Convention & Exhibition Centre, South Brisbane QLD, Australia, 3–6 December 2018.
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Improving memory in dementia and healthy older people with rVCS: a study protocol
Trung T. Ngo and Miguel E. Rentería (2018). Improving memory in dementia and healthy older people with rVCS: a study protocol. BDHP Ageing Theme Conference: “Improving the Health of Older People”, Translational Research Institute, Woolloongabba QLD, Australia, 3 August 2018.
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Persistent pain and depression: examining clinical comorbidity and shared risk factors
Campos-González, Adrián , Cuéllar-Partida, Gabriel , Byrne, Enda M. , Medland, Sarah E. , Hickie, Ian B. , Wray, Naomi R. , Martin, Nicholas G. , Rentería, Miguel E. and Ngo, Trung T. (2018). Persistent pain and depression: examining clinical comorbidity and shared risk factors. Brisbane Pain Research: Multidisciplinary Perspectives & Therapeutics, IMB Centre for Pain Research, St Lucia, QLD, 7 December 2018.
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A perceptual endophenotype for mental illness: Characterising normal genetic variation in the trait
Cuéllar-Partida, Gabriel, Ngo, Trung T., Couvy-Duchesne, Baptiste, Rentería, Miguel E., Colodro Conde, Lucia, Gordon, Scott D., Hansell, Narelle K., Medland, Sarah E., Wright, Margaret J. and Martin, Nicholas G. (2017). A perceptual endophenotype for mental illness: Characterising normal genetic variation in the trait. BLiSS 2017 — Brisbane Life Science ECR Symposium, Translational Research Institute, Brisbane, 24 November 2017.
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GWAS of complementary perceptual endophenotype measures: How do they rate?
Ngo, Trung T., Cuéllar-Partida, Gabriel, Couvy-Duchesne, Baptiste, Rentería, Miguel E., Colodro Conde, Lucia, Gordon, Scott D., Hansell, Narelle K., Medland, Sarah E., Wright, Margaret J. and Martin, Nicholas G. (2017). GWAS of complementary perceptual endophenotype measures: How do they rate?. Australasian Society for Bipolar & Depressive Disorders (ASBDD) 2017 Conference, Deakin Edge, Melbourne, 15–17 September 2017.
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Ngo, Trung T. and Rentería, Miguel E. (2017). Non-invasive DBS with caloric vestibular stimulation: clinical research applications and putative mechanisms. Asia-Pacific Centre for Neuromodulation Deep Brain Stimulation Symposium, Brisbane, Australia, 24–25 November 2017.
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Ngo, T. T., Couvy-Duchesne, B., Cuéllar-Partida, G., Rentería, M. E., Colodro Conde, L., Gordon, S. D., Hansell, N. K., Law, P. C. F., Miller, S. M., Medland, S. E., Wright, M. J. and Martin, N. G. (2016). Association of psychiatric profile measures with binocular rivalry rate (BRR): Implications for slow BRR as an endophenotype for bipolar disorder. International Society for Twin Studies Satellite Meeting, QIMR Berghofer Medical Research Institute, Brisbane, Australia, 20 June 2016. Cambridge, United Kingdom: Cambridge University Press. doi: 10.1017/thg.2016.66
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Ngo, Trung T., Law, Phillip C. F., Foley, Sharon R. and Capra, Carina (2016). Examining a novel visual task for identifying individuals at increased risk of developing mental illness. BLiSS 2016 — Brisbane Life Science ECR Symposium, Brisbane, Australia, 2 December 2016.
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Ngo, T. T., Barsdell, W. N., Arnold, C. A., Chou, M. J., New, P. W., Hill, S. T., Nunn, A. K., Brown, D. J., Gibson, S. J. and Miller, S. M. (2015). Bedside neuromodulation of persistent pain and allodynia using caloric vestibular stimulation: An effectiveness trial. 22nd World Congress of Neurology, Santiago, Chile, 31 October – 5 November 2015. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.jns.2015.08.304
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Binocular rivalry rate as a novel candidate endophenotype for bipolar disorder
Ngo, Trung, Rentería, Miguel E., Colodro Conde, Lucia, Couvy-Duchesne, Baptiste, Cuéllar-Partida, Gabriel, Hansell, Narelle K., Medland, Sarah E., Miller, Steven M., Wright, Margaret J. and Martin, Nicholas G. (2015). Binocular rivalry rate as a novel candidate endophenotype for bipolar disorder. XXIII rd World Congress of Psychiatric Genetics (WCPG), Toronto, Canada, 16–20 October 2015. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2015.09.010
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Miller, S. M., Law, P. C. F. and Ngo, T. T. (2015). Effects of drift speed and stimulus size on binocular rivalry rate and mixed percept duration in healthy individuals: Implications for endophenotype studies in clinical psychiatric groups. Society for Neuroscience 45th Annual Meeting, Chicago, USA, 17–21 October 2015.
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Ngo, T. T., Law, P. C. F. and Miller, S. M. (2015). Investigating optimal stimuli for large-scale endophenotype studies of binocular rivalry rate in bipolar disorder. Society for Mental Health Research Conference 2015, Sofitel Hotel, Brisbane, Qld, 2–4 December 2015.
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Law, P. C. F., Riddiford, J. A., Gurvich, C. T., Ngo, T. T. and Miller, S. M. (2015). Investigating the effect of stimulus variables and eye movement profiles on binocular rivalry rate: Implications for large-scale endophenotype studies. ICON 2014: XII International Conference on Cognitive Neuroscience, Brisbane Convention and Exhibition Centre, Queensland, Australia, 27–31 July 2014. Switzerland: Frontiers Research Foundation. doi: 10.3389/conf.fnhum.2015.217.00291
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A longitudinal investigation of binocular rivalry rate (BRR) in major psychotic disorders
Anderson-Schmidt, H., Gebel, L., Callista, K., Nierste, B., Glöckner, A., Budde, M., Heilbronner, U., Martin, N. G., Ngo, T. T., Miller, S. M. and Schulze, T. G. (2013). A longitudinal investigation of binocular rivalry rate (BRR) in major psychotic disorders. 21st World Congress of Psychiatric Genetics, Boston, USA, 17–21 October 2013.
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Development of a standardized system for perceptual rivalry research
Law, P. C. F., Paton, B. K., Thomson, R. H., Liu, G. B., Miller, S. M. and Ngo, T. T. (2013). Development of a standardized system for perceptual rivalry research. 33rd Annual Meeting of the Australian Neuroscience Society, Melbourne Exhibition and Convention Centre, Victoria, Australia, 3–6 February 2013. Australian Neuroscience Society.
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No relationship between binocular rivalry rate and eye movement variables
Law, P. C. F., Riddiford, J. A., Gurvich, C. T., Ngo, T. T. and Miller, S. M. (2013). No relationship between binocular rivalry rate and eye movement variables. 4th Australasian Cognitive Neuroscience Conference, Monash University, Melbourne, Australia, 28 November – 1 December 2013. Switzerland: Frontiers Research Foundation. doi: 10.3389/conf.fnhum.2013.212.00116
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Persistent pain and perceptual rivalry interactions: An exploratory study
Barsdell, W. N., Law, P. C. F., Gibson, S. J., Miller, S. M. and Ngo, T. T. (2013). Persistent pain and perceptual rivalry interactions: An exploratory study. 33rd Annual Scientific Meeting of the Australian Pain Society, Canberra, Australia, 17–20 March 2013. North Sydney, NSW Australia: Australian Society of Anaesthetists.
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Miller, S. M., Hansell, N. K., Ngo, T. T., Liu, G. B., Pettigrew, J. D., Wright, M. J. and Martin, N. G. (2012). Genetic contribution to individual variation in binocular rivalry rate, an endophenotype for bipolar disorder. 5th Biennial Conference of the International Society for Bipolar Disorders, Istanbul, Turkey, 14–17 March 2012. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1111/j.1399-5618.2012.00981.x
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Development of a binocular rivalry testing system for large-scale psychiatric and genetic studies
Law, P. C. F., Paton, B., Liu, G. B., Ngo, T. T. and Miller, S. M. (2011). Development of a binocular rivalry testing system for large-scale psychiatric and genetic studies. 1st Scientific Meeting of Biological Psychiatry Australia, Melbourne Cricket Ground, Melbourne, Australia, 7–8 November 2011.
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Barsdell, W. N., Ngo, T. T., Chou, M. J., Arnold, C. A., Nunn, A., Hill, S. T., Brown, D. J., Gibson, S. J. and Miller, S. M. (2011). Effects of a non-invasive vestibular-cortical activation technique on subjective ratings of persistent pain and mood. 1st Scientific Meeting of Biological Psychiatry Australia, Melbourne Cricket Ground, Melbourne, Australia, 7–8 November 2011.
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Effects of a non-invasive vestibulocortical activation technique in persistent pain states
Ngo, T. T., Barsdell, W. N., Chou, M. J., Arnold, C., Nunn, A., Hill, S. T., Brown, D. J., Gibson, S. J. and Miller, S. M. (2011). Effects of a non-invasive vestibulocortical activation technique in persistent pain states. 8th IBRO World Congress of Neuroscience, Florence, Italy, 14–18 July, 2011.
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An association between inequity-averse moral preference and risk aversion in decision-making
Palmer, C. J., Paton, B., Ngo, T. T., Thomson, R. H., Hohwy, J. and Miller, S. M. (2010). An association between inequity-averse moral preference and risk aversion in decision-making. ANS/AuPS 2010 — 30th Annual Meeting of the Australian Neuroscience Society, in conjunction with the 50th Anniversary Meeting of the Australian Physiological Society, Sydney Convention & Exhibition Centre, Darling Harbour, Sydney, 31 January – 3 February 2010. Australian Neuroscience Society.
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Caloric vestibular stimulation reduces allodynia in complex regional pain syndrome (CRPS) Type II
Ngo, T. T., Chou, M. J., Nunn, A., Arnold, C., Brown, D. J., Gibson, S. J. and Miller, S. M. (2010). Caloric vestibular stimulation reduces allodynia in complex regional pain syndrome (CRPS) Type II. ANS/AuPS 2010 — 30th Annual Meeting of the Australian Neuroscience Society, in conjunction with the 50th Anniversary Meeting of the Australian Physiological Society, Sydney Convention & Exhibition Centre, Darling Harbour, Sydney, 31 January – 3 February 2010. Australian Neuroscience Society.
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Genetic contribution to individual variation in binocular rivalry rate
Miller, S. M., Hansell, N. K., Ngo, T. T., Liu, G. B., Pettigrew, J. D., Martin, N. G. and Wright, M. J. (2010). Genetic contribution to individual variation in binocular rivalry rate. ANS/AuPS 2010 — 30th Annual Meeting of the Australian Neuroscience Society, in conjunction with the 50th Anniversary Meeting of the Australian Physiological Society, Sydney Convention & Exhibition Centre, Darling Harbour, Sydney, 31 January – 3 February 2010. Australian Neuroscience Society.
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Miller, S. M., Hansell, N. K., Ngo, T. T., Liu, G. B., Pettigrew, J. D., Martin, N. G. and Wright, M. J. (2010). Genetic contribution to individual variation in binocular rivalry rate, an endophenotype for bipolar disorder. 18th World Congress of Psychiatric Genetics, Athens, Greece, 3–7 October 2010. International Society of Psychiatric Genetics.
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The genetics of binocular rivalry
Miller, S. M., Hansell, N. K., Ngo, T. T., Liu, G. B., Pettigrew, J. D., Martin, N. G. and Wright, M. J. (2010). The genetics of binocular rivalry. 7th FENS Forum of European Neuroscience, Amsterdam, The Netherlands, 3–7 July, 2010. Federation of European Neuroscience Societies.
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Caloric vestibular stimulation: From diagnosis to therapy?
Miller, S. M. and Ngo, T. T. (2007). Caloric vestibular stimulation: From diagnosis to therapy?. World Psychiatric Association International Congress 2007, Melbourne Convention Centre, Melbourne, Australia, 28 November – 2 December 2007. London, United Kingdom: Sage. doi: 10.1080/00048670701724597
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Caloric vestibular stimulation: Perceptual rivalry and beyond
Ngo, T. T. and Miller, S. M. (2007). Caloric vestibular stimulation: Perceptual rivalry and beyond. 7th IBRO World Congress of Neuroscience, Melbourne Convention Centre, Melbourne, Australia, 12–17 July 2007. International Brain Research Organization.
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Coherence (full-field) rivalry but not half-field rivalry is mediated by interhemispheric switching
Ngo, T. T., Miller, S. M., Liu, G. B., Tilley, A. J. and Pettigrew, J. D. (2002). Coherence (full-field) rivalry but not half-field rivalry is mediated by interhemispheric switching. Australian Neuroscience Society Annual Meeting, Sydney, 3 - 6 February 2002. Australia: Australian Neuroscience Society.
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Ngo, T. T., Miller, S. M., Liu, G. B. and Pettigrew, J. D. (2002). Predominance of Rubin’s vase perceptual alternations changes with unilateral caloric vestibular stimulation. 32nd Annual Meeting of the Society for Neuroscience, Orlando, Florida, USA, 3–7 November 2002. Washington, DC United States: Society for Neuroscience.
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Coherence rivalry and caloric stimulation: Further support for an interhemispheric switch mechanism
Ngo, T. T., Miller, S. M., Liu, G. B. and Pettigrew, J. D. (2001). Coherence rivalry and caloric stimulation: Further support for an interhemispheric switch mechanism. 21st Annual Meeting of the Australian Neuroscience Society, Brisbane Convention Centre, Australia, 28 - 31 January 2001. Australia: Australian Neuroscience Society.
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Temporal properties of binocular rivalry in bipolar disorder, schizophrenia and major depression
Miller, S. M., Geffen, L. B., Gynther, B. D., Heslop, K. R., Liu, G. B., Ngo, T. T., Mitchell, P. B. and Pettigrew, J. D. (2001). Temporal properties of binocular rivalry in bipolar disorder, schizophrenia and major depression. 21st Annual Meeting of the Australian Neuroscience Society, Brisbane Convention Centre, Australia, 28–31 January 2001. Australian Neuroscience Society.
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Binocular rivalry is slow in bipolar disorder but not in schizophrenia or major depression
Miller, S. M., Liu, G. B., Ngo, T. T., Geffen, L. B., Gynther, B. D., Mitchell, P. B. and Pettigrew, J. D. (2000). Binocular rivalry is slow in bipolar disorder but not in schizophrenia or major depression. Congress of the Association of European Psychiatrists, Prague, Czech Republic, 28 October–1 November, 2000. Cedex, France: Elsevier. doi: 10.1016/S0924-9338(00)94234-2
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Coherence rivalry: The eyes don't have it!
Ngo, T. T., Miller, S. M., Liu, G. B. and Pettigrew, J. D. (2000). Coherence rivalry: The eyes don't have it!. 20th Annual Meeting Of The Australian Neuroscience Society, Melbourne Convention Centre, Melbourne, Victoria, Australia, 30 Jan - 2 Feb, 2000. Melbourne, Australia: Australian Neuroscience Society.
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Miller, S. M., Ngo, T. T., Liu, G. B. and Pettigrew, J. D. (2000). Unilateral caloric stimulation changes perceptual predominance during binocular rivalry with oblique gratings. 20th Annual Meeting of the Australian Neuroscience Society, Melbourne Convention Centre, Melbourne, Victoria, Australia, 30 January – 2 February 2000. Australian Neuroscience Society.
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A common neural mechanism for reversible figures and binocular rivalry?
Ngo, T. T., Miller, S. M., Liu, G. B., Tilley, A. J., Broerse, P. J. and Pettigrew, J. D. (1999). A common neural mechanism for reversible figures and binocular rivalry?. 19th Annual Meeting Of The Australian Neuroscience Society, Hobart, TAS Australia, 31 January - 3 February 1999. Sydney: Australian Neuroscience Society.
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Clinical studies of binocular rivalry
Miller, S. M., Liu, G. B., Ngo, T. T., Gynther, B. D., Geffen, L. B., Mitchell, P. B., Martin, N. G. and Pettigrew, J. D. (1999). Clinical studies of binocular rivalry. 5th IBRO World Congress of Neuroscience, Jerusalem, Israel, 11–15 July 1999. International Brain Research Organization.
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Neural mechanisms in binocular rivalry: Studies of image bias and alternation rate
Miller, S. M., Liu, G. B., Ngo, T. T., Hooper, G., Riek, S., Carson, R. G. and Pettigrew, J. D. (1999). Neural mechanisms in binocular rivalry: Studies of image bias and alternation rate. 19th Annual Meeting Of The Australian Neuroscience Society, Hobart, TAS, Australia, 31 January – 3 February 1999. Australian Neuroscience Society.
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Slow binocular rivalry in bipolar disorder
Miller, S. M., Ngo, T. T., Liu, G. B., Gynther, B. D., Geffen, L. B., Mitchell, P. B., Martin, N. G. and Pettigrew, J. D. (1999). Slow binocular rivalry in bipolar disorder. Annual Scientific Meeting of the Australasian Society for Psychiatric Research, University of New South Wales, Sydney, Australia, 2–3 December 1999.
Other Outputs
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Advancing the interhemispheric switch model of perceptual rivalry
Ngo, Trung Thanh (2009). Advancing the interhemispheric switch model of perceptual rivalry. PhD Thesis, School of Biomedical Sciences and School of Psychology, The University of Queensland.
Possible Research Projects
Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.
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Honours / Masters / PhD / DPsych / DBiotech / MBBS / MD research projects
The following research projects are open to enthusiastic & driven individuals from a wide range of background disciplines/industry experience, e.g., biomedical/electrical engineering, physics, computer science, mathematics & statistics, biological/life sciences, medicine & allied health, information technology, psychology:
Minimal phenotyping: Perceptual & cognitive biomarkers
- validating the clinical utility of novel visual task measures for identifying individuals at increased risk of developing mental illness (e.g., young people, at-risk/early psychosis cohorts).
- multi-platform development of candidate diagnostic/endophenotype perceptual & cognitive task measures for large-scale user-friendly testing in genotyped and at-risk/youth cohorts (e.g., web, mobile, tablet, gaming, virtual reality).
VCS — VestibuloCortical Stimulation: Applications & mechanisms
- effectiveness of non-invasive vestibular neuromodulation protocols as a treatment for psychiatric & neurological illnesses (e.g., depression, bipolar disorder, post-traumatic stress disorder, dementia, epilepsy, persistent pain) and enhancing affective-cognitive Resilience in Contested Environments #RiCE | #PrecisionPainMedicine
- clinical and performance-enhancing applications of repeated VCS (#rVCS) — and the genetics & neuroimaging of its (therapeutic) response — with the aim of elucidating novel electroceutical pathways, response biomarkers and personalised treatment protocols across a spectrum psychiatric & neurological disorders | 'Electroceutomics'
MedTech & Biotech platform development
- autonomic activity recording devices with real-time analysis output of endogenous rhythms and their clinical (diagnostic) utility in psychiatry, neurology & sleep medicine | #PrecisionSleepMedicine
- portable/wearable devices with integrated software applications for (i) perceptual rivalry viewing (e.g., stereoscopic 3D displays), data collection & analyses; (ii) probing interhemispheric rhythms (e.g., autonomic respiratory/nasal cycle periodicity); and (iii) inducing, recording & real-time analysis output of VCS.
Phylogenetics & evolution of bistable switching and VCS network
- from bacterial chemotaxis & fruit fly optomotor responses to binary decision-making in mammals (e.g., approach/avoidance choice behaviour) and disordered mood/cognitive states in humans (e.g., mania/depression, denial/insight)
- investigating the comparative genetics, neural network dynamics (e.g., vestibulocortical circuitry) and molecular mechanisms of bistable (anti-phase) interhemispheric oscillations — which have been observed across a range of phenotypes (e.g., biological rhythms, autonomic functions, oculomotor activity, perception/attention, cognitive/behaviour changes) and in different species (e.g., Drosophila, sandlance, birds, cetaceans, rodents, humans) | #PrecisionSwitchMedicine
Scientometrics of research benefits
- developing quantitative indicators of interdisciplinary conceptual & empirical synthesis, scientific impact, translational & innovation outcomes using machine learning (A.I.) analytical methods.
