The University of Queensland

Imaging flow cytometric analysis of primary bone marrow erythroblastic islands

Tay, Joshua, Bisht, Kavita, Winkler, Ingrid G. and Levesque, Jean-Pierre (2023). Imaging flow cytometric analysis of primary bone marrow erythroblastic islands. Spectral and imaging cytometry methods and protocols. (pp. 43-61) edited by Natasha S. Barteneva and Ivan A. Vorobjev. New York, NY: Humana Press Inc.. doi: 10.1007/978-1-0716-3020-4_3

Bacterial Lipopolysaccharides Exacerbate Neurogenic Heterotopic Ossification Development

Salga, Marjorie, Samuel, Selwin G., Tseng, Hsu‐Wen, Gatin, Laure, Girard, Dorothée, Rival, Bastien, Barbier, Valerie, Bisht, Kavita, Shatunova, Svetlana, Debaud, Charlotte, Winkler, Ingrid G., Paquereau, Julie, Dinh, Aurélien, Genêt, Guillaume, Kerever, Sébastien, Abback, Paer‐Sélim, Banzet, Sébastien, Genêt, François, Lévesque, Jean‐Pierre and Alexander, Kylie A. (2023). Bacterial Lipopolysaccharides Exacerbate Neurogenic Heterotopic Ossification Development. Journal of Bone and Mineral Research, 38 (11), 1-18. doi: 10.1002/jbmr.4905

GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection

Foo, Cheng Xiang, Bartlett, Stacey, Chew, Keng Yih, Ngo, Minh Dao, Bielefeldt-Ohmann, Helle, Jayakody Arachchige, Buddhika, Matthews, Benjamin, Reed, Sarah, Wang, Ran, Smith, Christian, Sweet, Matthew J., Burr, Lucy, Bisht, Kavita, Shatunova, Svetlana, Sinclair, Jane E., Parry, Rhys, Yang, Yuanhao, Lévesque, Jean-Pierre, Khromykh, Alexander, Rosenkilde, Mette Marie, Short, Kirsty R. and Ronacher, Katharina (2023). GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection. European Respiratory Journal, 61 (3) 2201306, 1-15. doi: 10.1183/13993003.01306-2022

Macrophages form erythropoietic niches and regulate iron homeostasis to adapt erythropoiesis in response to infections and inflammation

Lévesque, Jean-Pierre, Summers, Kim M., Bisht, Kavita, Millard, Susan M., Winkler, Ingrid G. and Pettit, Allison R. (2021). Macrophages form erythropoietic niches and regulate iron homeostasis to adapt erythropoiesis in response to infections and inflammation. Experimental Hematology, 103, 1-14. doi: 10.1016/j.exphem.2021.08.011

Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model

Walweel, K., Boon, A. C., See Hoe, L. E., Obonyo, N. G., Pedersen, S. E., Diab, S. D., Passmore, M. R., Hyslop, K., Colombo, S. M., Bartnikowski, N. J., Bouquet, M., Wells, M. A., Black, D. M., Pimenta, L. P., Stevenson, A. K., Bisht, K., Skeggs, K., Marshall, L., Prabhu, A., James, L. N., Platts, D. G., Macdonald, P. S., McGiffin, D. C., Suen, J. Y. and Fraser, J. F. (2021). Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model. Biomedical Journal, 45 (5), 776-787. doi: 10.1016/j.bj.2021.10.007

Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilization

Bisht, Kavita, McGirr, Crystal, Lee, Seo-Youn, Tseng, Hsu-Wen, Fleming, Whitney, Alexander, Kylie A., Matsumoto, Taichi, Barbier, Valérie, Sims, Natalie A., Müller-Newen, Gerhard, Winkler, Ingrid G., Bonig, Halvard and Lévesque, Jean-Pierre (2021). Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilization. Leukemia, 36 (2), 333-347. doi: 10.1038/s41375-021-01413-z

Role of macrophages and phagocytes in orchestrating normal and pathologic hematopoietic niches

Lévesque, Jean-Pierre, Summers, Kim M., Millard, Susan, Bisht, Kavita, Winkler, Ingrid G. and Pettit, Allison R. (2021). Role of macrophages and phagocytes in orchestrating normal and pathologic hematopoietic niches. Experimental Hematology, 100, 12-31. doi: 10.1016/j.exphem.2021.07.001

Bacterial lipopolysaccharides suppress erythroblastic islands and erythropoiesis in the bone marrow in an extrinsic and G- CSF-, IL-1-, and TNF-independent manner

Bisht, Kavita, Tay, Joshua, Wellburn, Rebecca N., McGirr, Crystal, Fleming, Whitney, Nowlan, Bianca, Barbier, Valerie, Winkler, Ingrid G. and Levesque, Jean-Pierre (2020). Bacterial lipopolysaccharides suppress erythroblastic islands and erythropoiesis in the bone marrow in an extrinsic and G- CSF-, IL-1-, and TNF-independent manner. Frontiers in Immunology, 11 583550, 1-16. doi: 10.3389/fimmu.2020.583550

Endothelin receptor antagonist improves donor lung function in an ex vivo perfusion system

Walweel, K., Skeggs, K., Boon, A. C., See Hoe, L. E., Bouquet, M., Obonyo, N. G., Pedersen, S. E., Diab, S. D., Passmore, M. R., Hyslop, K., Wood, E. S., Reid, J., Colombo, S. M., Bartnikowski, N. J., Wells, M. A., Black, D., Pimenta, L. P., Stevenson, A. K., Bisht, K., Marshall, L., Prabhu, D. A., James, L., Platts, D. G., MacDonald, P. S., McGiffin, D. C., Suen, J. Y. and Fraser, J. F. (2020). Endothelin receptor antagonist improves donor lung function in an ex vivo perfusion system. Journal of Biomedical Science, 27 (1) 96, 96. doi: 10.1186/s12929-020-00690-7

Imaging flow cytometry reveals that granulocyte colony-stimulating factor treatment causes loss of erythroblastic islands in the mouse bone marrow

Tay, Joshua, Bisht, Kavita, McGirr, Crystal, Millard, Susan M., Pettit, Allison R., Winkler, Ingrid G. and Levesque, Jean-Pierre (2020). Imaging flow cytometry reveals that granulocyte colony-stimulating factor treatment causes loss of erythroblastic islands in the mouse bone marrow. Experimental Hematology, 82, 33-42. doi: 10.1016/j.exphem.2020.02.003

Oncostatin M is a novel niche factor that restrains hematopoietic stem cell mobilization in response to G-CSF and CXCR4 antagonist plerixafor

Bisht, Kavita, McGirr, Crystal, Alexander, Kylie A, Fleming, Whitney, Sims, Natalie, Newen, Gerhard Müller-, Winkler, Ingrid G and Levesque, Jean-Pierre (2019). Oncostatin M is a novel niche factor that restrains hematopoietic stem cell mobilization in response to G-CSF and CXCR4 antagonist plerixafor. Blood, 134 (Supplement_1), 4469-4469. doi: 10.1182/blood-2019-127431

Deletion of biliverdin reductase A in myeloid cells promotes chemokine expression and chemotaxis in part via a complement C5a­–C5aR1 pathway

Bisht, Kavita, Canesin, Giacomo, Cheytan, Tasneem, Li, Mailin, Nemeth, Zsuzsanna, Csizmadia, Eva, Woodruff, Trent M., Stec, David E., Bulmer, Andrew C., Otterbein, Leo E. and Wegiel, Barbara (2019). Deletion of biliverdin reductase A in myeloid cells promotes chemokine expression and chemotaxis in part via a complement C5a­–C5aR1 pathway. The Journal of Immunology, 202 (10), ji1701443-2990. doi: 10.4049/jimmunol.1701443

HIF prolyl hydroxylase inhibitor FG-4497 enhances mouse hematopoietic stem cell mobilization via VEGFR2/KDR

Bisht, Kavita, Brunck, Marion E., Matsumoto, Taichi, McGirr, Crystal, Nowlan, Bianca, Fleming, Whitney, Keech, Thomas, Magor, Graham, Perkins, Andrew C., Davies, Julie, Walkinshaw, Gail, Flippin, Lee, Winkler, Ingrid G. and Levesque, Jean-Pierre (2019). HIF prolyl hydroxylase inhibitor FG-4497 enhances mouse hematopoietic stem cell mobilization via VEGFR2/KDR. Blood Advances, 3 (3), 406-418. doi: 10.1182/bloodadvances.2018017566

Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock

Passmore, Margaret R., Byrne, Liam, Obonyo, Nchafatso G., See Hoe, Louise E., Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Bisht, Kavita, Tung, John-Paul, Fauzi, Mohd H., Narula, Monica, Pedersen, Sanne E., Esguerra-Lallen, Arlanna, Simonova, Gabriela, Sultana, Annette, Anstey, Chris M., Shekar, Kiran, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2018). Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock. Respiratory Research, 19 (1) 231, 231. doi: 10.1186/s12931-018-0935-4

Augmented renal clearance in traumatic brain injury: a single-center observational study of atrial natriuretic peptide, cardiac output, and creatinine clearance

Udy, Andrew A., Jarrett, Paul, Lassig-Smith, Melissa, Stuart, Janine, Starr, Therese, Dunlop, Rachel, Deans, Renae, Roberts, Jason A., Senthuran, Siva, Boots, Robert, Bisht, Kavita, Bulmer, Andrew C. and Lipman, Jeffrey (2017). Augmented renal clearance in traumatic brain injury: a single-center observational study of atrial natriuretic peptide, cardiac output, and creatinine clearance. Journal of Neurotrauma, 34 (1), 137-144. doi: 10.1089/neu.2015.4328

Alterations of tumor microenvironment by carbon monoxide impedes lung cancer growth

Nemeth, Zsuzsanna, Csizmadia, Eva, Vikstrom, Lisa, Li, Mailin, Bisht, Kavita, Feizi, Alborz, Otterbein, Sherrie, Zuckerbraun, Brian, Costa, Daniel B., Pandolfi, Pier Paolo, Fillinger, Janos, Döme, Balazs, Otterbein, Leo E. and Wegiel, Barbara (2016). Alterations of tumor microenvironment by carbon monoxide impedes lung cancer growth. Oncotarget, 7 (17), 23919-23932. doi: 10.18632/oncotarget.8081

Biliverdin modulates the expression of C5aR in response to endotoxin in part via mTOR signaling

Bisht, Kavita, Wegiel, Barbara, Tampe, Jens, Neubauer, Oliver, Wagner, Karl-Heinz, Otterbein, Leo E. and Bulmer, Andrew C. (2014). Biliverdin modulates the expression of C5aR in response to endotoxin in part via mTOR signaling. Biochemical and Biophysical Research Communications, 449 (1), 94-99. doi: 10.1016/j.bbrc.2014.04.150

Endogenous tetrapyrroles influence leukocyte responses to lipopolysaccharide in human blood: pre-clinical evidence demonstrating the anti-inflammatory potential of biliverdin

Bisht, Kavita, Tampe, Jens, Shing, Cecilia, Bakrania, Bhavisha, Winearls, James, Fraser, John, Wagner, Karl-Heinz and Bulmer, Andrew C. (2014). Endogenous tetrapyrroles influence leukocyte responses to lipopolysaccharide in human blood: pre-clinical evidence demonstrating the anti-inflammatory potential of biliverdin. Journal of Clinical and Cellular Immunology, 5 (3), 1000218. doi: 10.4172/2155-9899.1000218

Reduced circulating oxidized LDL is associated with hypocholesterolemia and enhanced thiol status in Gilbert syndrome

Boon, Ai-Ching, Hawkins, Clare L., Bisht, Kavita, Coombes, Jeff S., Bakrania, Bhavisha, Wagner, Karl-Heinz and Bulmer, Andrew C. (2012). Reduced circulating oxidized LDL is associated with hypocholesterolemia and enhanced thiol status in Gilbert syndrome. Free Radical Biology and Medicine, 52 (10), 2120-2127. doi: 10.1016/j.freeradbiomed.2012.03.002

Curcumin, resveratrol and flavonoids as anti-inflammatory, cyto- and DNA-protective dietary compounds

Bisht, Kavita, Wagner, Karl-Heinz and Bulmer, Andrew C. (2010). Curcumin, resveratrol and flavonoids as anti-inflammatory, cyto- and DNA-protective dietary compounds. Toxicology, 278 (1), 88-100. doi: 10.1016/j.tox.2009.11.008

Curcumin enhances non-inflammatory phagocytic activity of RAW264.7 cells

Bisht, Kavita, Choi, Woo H., Park, Shin Y., Chung, Moon K. and Koh, Woo S. (2009). Curcumin enhances non-inflammatory phagocytic activity of RAW264.7 cells. Biochemical and Biophysical Research Communications, 379 (2), 632-636. doi: 10.1016/j.bbrc.2008.12.135

Erythropoiesis suppression by bacterial liposaccharides is extrinsically mediated independently of G-CSF

Bisht, Kavita , Tay, Joshua , Jacobsen, Rebecca , McGirr, Crystal , Fleming, Whitney , Nowlan, Bianca , Barbier, Valerie , Winkler, Ingrid and Levesque, Jean-Pierre (2019). Erythropoiesis suppression by bacterial liposaccharides is extrinsically mediated independently of G-CSF. International Society of Experimental Hematology, Brisbane, Australia, 22-25 August 2019. Philadelphia, PA, United States: Elsevier.

Hematopoietic Stem Cell Mobilization and Erythropoiesis Suppression in Response to Lipopolysaccharides Involve Two Distinct Tlr4-Depedent Mechanisms with Different Requirement for G-Csf Receptors

Bisht, Kavita, Jacobsen, Rebecca, Brunck, Marion, Keech, Thomas, McGirr, Crystal, Nowlan, Bianca, Barbier, Valerie, Winkler, Ingrid and Levesque, Jean-Pierre (2016). Hematopoietic Stem Cell Mobilization and Erythropoiesis Suppression in Response to Lipopolysaccharides Involve Two Distinct Tlr4-Depedent Mechanisms with Different Requirement for G-Csf Receptors. 45th Annual Scientific Meeting of the International-Society-for-Experimental-Hematology (ISEH), San Diego, CA, United States, 25-28 August 2016. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2016.06.096

Suppression of medullar erythropoiesis in response to bacterial lipopolysaccharides (LPS) involves two distinct TLR4-dependent mechanisms with contrasted requirements for G-CSF receptors

Bisht, Kavita, Jacobsen, Rebecca, Nowlan, Bianca, McGirr, Crystal, Brunck, Marion, Keech, Thomas, Winkler, Ingrid G. and Levesque, Jean-Pierre (2016). Suppression of medullar erythropoiesis in response to bacterial lipopolysaccharides (LPS) involves two distinct TLR4-dependent mechanisms with contrasted requirements for G-CSF receptors. 58th Annual Meeting and Exposition of the American Society of Hematology (ASH), San Diego, CA, United States, 3-6 December 2016. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.V128.22.546.546

Carbon monoxide targets Notch1 and MAPK-ERK1/2 signaling pathways to block growth of lung carcinoma

Nemeth, Zsuzsanna, Csizmadia, Eva, Vikstrom, Lisa, Li, Mailin, Bisht, Kavita, Feizi, Alborz, Gallo, David, Otterbein, Leo, Fillinger, Janos, Dome, Balazs, B. Costa, Daniel and Wegiel, Barbara (2015). Carbon monoxide targets Notch1 and MAPK-ERK1/2 signaling pathways to block growth of lung carcinoma. AACR 106th Annual Meeting 2015, Philadelphia, PA, United States, 18-22 April 2015. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2015-416

Reduced LDL oxidation is secondary to protection from in vivo thiol oxidation and hypocholesterolemia in Gilbert's syndrome

Bulmer, Andrew Cameron, Boon, Ai-Ching, Hawkins, Clare, Bisht, Kavita, Coombes, Jeff and Wagner, Karl-Heinz (2012). Reduced LDL oxidation is secondary to protection from in vivo thiol oxidation and hypocholesterolemia in Gilbert's syndrome. Experimental Biology Meeting, San Diego, United States, 21-25 April 2012. Bethesda, MD, United States: Federation of American Societies for Experimental Biology.