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Dr Yvonne Eiby

Senior Research Fellow

Medical School (Office & AME)
Faculty of Medicine
y.eiby@uq.edu.au
+61 7 334 66010

Overview

Research Interests

  • Neonatal physiology
    Improving brain outcomes for preterm infants by developing effective cardiovascular and nutritional support in early life.

Qualifications

  • Doctor of Philosophy, The University of Queensland
  • Bachelor (Honours) of Science (Advanced), The University of Queensland
  • Bachelor of Science, The University of Queensland

Publications

  • Journal Article: Red cell infusion but not saline is effective for volume expansion in preterm piglets

    Eiby, Yvonne A., Wright, Ian M. R., Stark, Michael J. and Lingwood, Barbara E. (2023). Red cell infusion but not saline is effective for volume expansion in preterm piglets. Pediatric Research, 94 (1), 112-118. doi: 10.1038/s41390-022-02403-2

  • Journal Article: Reduced blood volume decreases cerebral blood flow in preterm piglets

    Eiby, Yvonne A., Shrimpton, Nicole Y., Wright, Ian M. R., Lumbers, Eugenie R., Colditz, Paul B., Duncombe, Greg J. and Lingwood, Barbara E. (2018). Reduced blood volume decreases cerebral blood flow in preterm piglets. The Journal of Physiology, 596 (23), 6033-6041. doi: 10.1113/JP275583

  • Conference Publication: Preterm piglets are a model of human preterm infant sulphate deficiency

    Dawson, P. A., Eiby, Y. A., Barnes, S. K., Boyd, R. N., Badawi, N., Koorts, P. J., Kumar, S., Flenady, V. J., Hurrion, E. M, Colditz, P. B. and Lingwood, B. E. (2018). Preterm piglets are a model of human preterm infant sulphate deficiency. 22nd Annual Congress of the Perinatal Society of Australia and New Zealand (PSANZ), Auckland, New Zealand, 25–28 March 2018. Chichester, West Sussex United Kingdom: Wiley. doi: 10.1111/jpc.13882_186

  • Journal Article: Inotropes do not increase cardiac output or cerebral blood flow in preterm piglets

    Eiby, Yvonne A., Shrimpton, Nicole Y. , Wright, Ian M. R. , Lumbers, Eugenie R., Colditz, Paul B. , Duncombe, Greg J. and Lingwood, Barbara E.  (2016). Inotropes do not increase cardiac output or cerebral blood flow in preterm piglets. Pediatric Research, 80 (6), 870-879. doi: 10.1038/pr.2016.156

  • Journal Article: A Pig Model of the Preterm Neonate: Anthropometric and Physiological Characteristics

    Eiby, Yvonne A., Wright, Layne L., Kalanjati, Viskasari P., Miller, Stephanie M., Bjorkman, Stella T., Keates, Helen L., Lumbers, Eugenie R., Colditz, Paul B. and Lingwood, Barbara E. (2013). A Pig Model of the Preterm Neonate: Anthropometric and Physiological Characteristics. PLoS ONE, 8 (7) e68763, e68763. doi: 10.1371/journal.pone.0068763

View all Publications

Grants

View all Grants

Supervision

View all Supervision

Available Projects

  • Early tranfusion to prevent hypovolemia in preterm newborns

    PhD Scholarship

    The Perinatal Research Centre at The University of Queensland, Australia, is currently seeking a PhD candidate for an NHMRC funded research project testing early transfusion in preterm neonates. The successful candidate will be located at the UQ Centre for Clinical Research on the Royal Brisbane and Womens’ Hospital campus at Herston, Brisbane. A UQ funded Scholarship is available and more information regarding eligibility, stipend, and how to apply can be found at:

    https://scholarships.uq.edu.au/scholarship/earmarked-scholarships-support-category-1-project-grants

    Project description

    There are currently no clinical interventions that effectively prevent cardiovascular deterioration in premature babies. This project will use an established pre-clinical model to test the efficacy and safety of early transfusion for preventing hypovolemia and maintaining oxygen supply to the brain. Studying the cardiovascular and lymphatic physiology of preterm neonates using a large animal pre-clinical model is essential to the rational design of effective interventions to manage blood volume. This is a fully funded project.

    The Team

    This multidisciplinary team, led by Dr Yvonne Eiby, is comprised of neonatologists, vets and scientists. Our research improves the clinical care of preterm infants in order to protect the developing brain.

    Pre-clinical model

    The PhD candidate will gain hands on experience in our pre-clinical tertiary level neonatal intensive care unit and be trained in intensive care techniques such as intubation, ventilation and catheterization. Previous work with animals in not necessary. The candidate will also be trained in laboratory techniques as required by the project.

    For further information contact: Yvonne Eiby (y.eiby@uq.edu.au)

  • Lymphatic function in preterm piglets

    There is very little known about the lymphatic function of premature babies. We have shown in our preterm piglet model that there are substantial reductions in lymphatic flow over the first day of life. This project will investigate how clinical management strategies influence flow rates with a view to develop novel interventions to reduce the high rates of disability in this vulnerable population.

View all Available Projects

Publications

Featured Publications

  • Red cell infusion but not saline is effective for volume expansion in preterm piglets

    Eiby, Yvonne A., Wright, Ian M. R., Stark, Michael J. and Lingwood, Barbara E. (2023). Red cell infusion but not saline is effective for volume expansion in preterm piglets. Pediatric Research, 94 (1), 112-118. doi: 10.1038/s41390-022-02403-2

  • Reduced blood volume decreases cerebral blood flow in preterm piglets

    Eiby, Yvonne A., Shrimpton, Nicole Y., Wright, Ian M. R., Lumbers, Eugenie R., Colditz, Paul B., Duncombe, Greg J. and Lingwood, Barbara E. (2018). Reduced blood volume decreases cerebral blood flow in preterm piglets. The Journal of Physiology, 596 (23), 6033-6041. doi: 10.1113/JP275583

  • Preterm piglets are a model of human preterm infant sulphate deficiency

    Dawson, P. A., Eiby, Y. A., Barnes, S. K., Boyd, R. N., Badawi, N., Koorts, P. J., Kumar, S., Flenady, V. J., Hurrion, E. M, Colditz, P. B. and Lingwood, B. E. (2018). Preterm piglets are a model of human preterm infant sulphate deficiency. 22nd Annual Congress of the Perinatal Society of Australia and New Zealand (PSANZ), Auckland, New Zealand, 25–28 March 2018. Chichester, West Sussex United Kingdom: Wiley. doi: 10.1111/jpc.13882_186

  • Inotropes do not increase cardiac output or cerebral blood flow in preterm piglets

    Eiby, Yvonne A., Shrimpton, Nicole Y. , Wright, Ian M. R. , Lumbers, Eugenie R., Colditz, Paul B. , Duncombe, Greg J. and Lingwood, Barbara E.  (2016). Inotropes do not increase cardiac output or cerebral blood flow in preterm piglets. Pediatric Research, 80 (6), 870-879. doi: 10.1038/pr.2016.156

  • A Pig Model of the Preterm Neonate: Anthropometric and Physiological Characteristics

    Eiby, Yvonne A., Wright, Layne L., Kalanjati, Viskasari P., Miller, Stephanie M., Bjorkman, Stella T., Keates, Helen L., Lumbers, Eugenie R., Colditz, Paul B. and Lingwood, Barbara E. (2013). A Pig Model of the Preterm Neonate: Anthropometric and Physiological Characteristics. PLoS ONE, 8 (7) e68763, e68763. doi: 10.1371/journal.pone.0068763

Journal Article

Conference Publication

  • Preterm piglets are a model of human preterm infant sulphate deficiency

    Dawson, P. A., Eiby, Y. A., Barnes, S. K., Boyd, R. N., Badawi, N., Koorts, P. J., Kumar, S., Flenady, V. J., Hurrion, E. M, Colditz, P. B. and Lingwood, B. E. (2018). Preterm piglets are a model of human preterm infant sulphate deficiency. 22nd Annual Congress of the Perinatal Society of Australia and New Zealand (PSANZ), Auckland, New Zealand, 25–28 March 2018. Chichester, West Sussex United Kingdom: Wiley. doi: 10.1111/jpc.13882_186

  • Plasma sulphate levels decline in the neonatal preterm piglet

    Dawson, Paul, Lingwood, Barbara, Eiby, Yvonne, Barnes, Samuel, Colditz, Paul, Boyd, Roslyn, Badawi, Nadia, Koorts, Pieter, Kumar, Sailesh, Flenady, Vicki and Hurrion, Elizabeth (2017). Plasma sulphate levels decline in the neonatal preterm piglet. 21st Annual Congress of the Perinatal Society of Australia and New Zealand (PSANZ), Canberra, Australia, 2–5 April, 2017. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jpc.13494_68

  • Pilot trial of early blood transfusions for supporting cardiovascular function and cerebral oxygen delivery in preterm piglets

    Eiby, Yvonne, Bjorkman, Tracey, Wixey, Julie, Chand, Kirat, Colditz, Paul and Lingwood, Barbara (2016). Pilot trial of early blood transfusions for supporting cardiovascular function and cerebral oxygen delivery in preterm piglets. 30th Annual meeting Fetal and Neonatal Workshop of Australia and New Zealand, Magnetic Island, QLD, Australia, 19-21 May 2016.

  • Expression of Adrenoceptor Subtypes in the Preterm Pig Heart

    Kim, M. Y., Eiby, Y. A., Lumbers, E. R., Boyce, A. C., Gibson, K. J. and Lingwood, B. E. (2011). Expression of Adrenoceptor Subtypes in the Preterm Pig Heart. Unknown, Unknown, Unknown. New York, NY, United States: Nature Publishing Group. doi: 10.1038/pr.2011.482

Other Outputs

  • Measuring blood volume in preterm piglets

    Morwood, Holly, Bakrania, Bhavisha A., Wright, Ian M. R., Eiby, Yvonne A. and Lingwood, Barbara E. (2022). Measuring blood volume in preterm piglets. The University of Queensland. (Dataset) doi: 10.48610/65b722d

  • Cardiac TRPM6 and 7 piglets

    Forbes, Elizabeth, Bakrania, Bhavisha, Steans, Sarah, Moritz, Karen, Lingwood, Barbara and Eiby, Yvonne (2022). Cardiac TRPM6 and 7 piglets. The University of Queensland. (Dataset) doi: 10.48610/0dac82b

  • Incubation biology of the Australian Brush-turkey (Alectura lathami)

    Yvonne Eiby (2009). Incubation biology of the Australian Brush-turkey (Alectura lathami). PhD Thesis, School of Biological Sciences, The University of Queensland.

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Capillary ultrastructure and fluid loss from the circulation in preterm piglets

    Doctor Philosophy — Principal Advisor

  • Factors driving early plasma loss in preterm piglets

    Doctor Philosophy — Principal Advisor

    Other advisors:

  • Molecular analyses of sulfation pathways in neurodevelopment following preterm birth

    Doctor Philosophy — Associate Advisor

    Other advisors:

  • Characterisation of sulfate deficiency on preterm neonatal bone growth and development.

    Doctor Philosophy — Associate Advisor

    Other advisors:

Possible Research Projects

Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.

  • Early tranfusion to prevent hypovolemia in preterm newborns

    PhD Scholarship

    The Perinatal Research Centre at The University of Queensland, Australia, is currently seeking a PhD candidate for an NHMRC funded research project testing early transfusion in preterm neonates. The successful candidate will be located at the UQ Centre for Clinical Research on the Royal Brisbane and Womens’ Hospital campus at Herston, Brisbane. A UQ funded Scholarship is available and more information regarding eligibility, stipend, and how to apply can be found at:

    https://scholarships.uq.edu.au/scholarship/earmarked-scholarships-support-category-1-project-grants

    Project description

    There are currently no clinical interventions that effectively prevent cardiovascular deterioration in premature babies. This project will use an established pre-clinical model to test the efficacy and safety of early transfusion for preventing hypovolemia and maintaining oxygen supply to the brain. Studying the cardiovascular and lymphatic physiology of preterm neonates using a large animal pre-clinical model is essential to the rational design of effective interventions to manage blood volume. This is a fully funded project.

    The Team

    This multidisciplinary team, led by Dr Yvonne Eiby, is comprised of neonatologists, vets and scientists. Our research improves the clinical care of preterm infants in order to protect the developing brain.

    Pre-clinical model

    The PhD candidate will gain hands on experience in our pre-clinical tertiary level neonatal intensive care unit and be trained in intensive care techniques such as intubation, ventilation and catheterization. Previous work with animals in not necessary. The candidate will also be trained in laboratory techniques as required by the project.

    For further information contact: Yvonne Eiby (y.eiby@uq.edu.au)

  • Lymphatic function in preterm piglets

    There is very little known about the lymphatic function of premature babies. We have shown in our preterm piglet model that there are substantial reductions in lymphatic flow over the first day of life. This project will investigate how clinical management strategies influence flow rates with a view to develop novel interventions to reduce the high rates of disability in this vulnerable population.

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Links

ResearcherID: F-2772-2010

ORCID: 0000-0003-0079-7796

Scopus ID: 25521498200

Personal Profile: Link

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