The University of Queensland

The Efficacy of Palmitoylethanolamide (Levagen+) on the Incidence and Symptoms of Upper Respiratory Tract Infection—A Double Blind, Randomised, Placebo-Controlled Trial

Rao, Amanda, Skinner, Rachael and Briskey, David (2023). The Efficacy of Palmitoylethanolamide (Levagen+) on the Incidence and Symptoms of Upper Respiratory Tract Infection—A Double Blind, Randomised, Placebo-Controlled Trial. Nutrients, 15 (20) 4453, 4453. doi: 10.3390/nu15204453

Modulating inflammation and immune function through the dietary nitrate-nitrite-nitric oxide pathway to promote vascular health: insights from a randomized, controlled study

Raubenheimer, Kyle, Hickey, Danica, Leveritt, Michael, Fassett, Robert, Ortiz de Zevallos Munoz, Joaquin, Allen, Jason D., Briskey, David, Parker, Tony J., Kerr, Graham, Peake, Jonathan M., Pecheniuk, Natalie M. and Neubauer, Oliver (2023). Modulating inflammation and immune function through the dietary nitrate-nitrite-nitric oxide pathway to promote vascular health: insights from a randomized, controlled study. Free Radical Biology and Medicine, 201, 51-52. doi: 10.1016/j.freeradbiomed.2023.03.209

A double-blind, randomised cross-over study to evaluate the absorption of a commercially available Ginkgo biloba extract compared to the liposomal extract Ginkgosome

Briskey, David and Rao, Amanda (2022). A double-blind, randomised cross-over study to evaluate the absorption of a commercially available Ginkgo biloba extract compared to the liposomal extract Ginkgosome. BMC Complementary Medicine and Therapies, 22 (1) 206, 1-6. doi: 10.1186/s12906-022-03679-x

Effectiveness of “Moro” blood orange Citrus sinensis Osbeck (Rutaceae) standardized extract on weight loss in overweight but otherwise healthy men and women—a randomized double-blind placebo-controlled study

Briskey, David, Malfa, Giuseppe Antonio and Rao, Amanda (2022). Effectiveness of “Moro” blood orange Citrus sinensis Osbeck (Rutaceae) standardized extract on weight loss in overweight but otherwise healthy men and women—a randomized double-blind placebo-controlled study. Nutrients, 14 (3) 427. doi: 10.3390/nu14030427

The Effect of a Dispersible Curcumin (HydroCurc®) Compared to a Placebo for Reducing Joint Pain in an Adult Population - A Randomised, Double-Blind Study

Briskey, David, Roche, Georgia and Rao, Amanda (2022). The Effect of a Dispersible Curcumin (HydroCurc®) Compared to a Placebo for Reducing Joint Pain in an Adult Population - A Randomised, Double-Blind Study. Complementary Medicine Research, 29 (6), 429-436. doi: 10.1159/000524689

Palmitoylethanolamide for sleep disturbance. A double-blind, randomised, placebo-controlled interventional study

Rao, Amanda, Ebelt, Phillippa, Mallard, Alistair and Briskey, David (2021). Palmitoylethanolamide for sleep disturbance. A double-blind, randomised, placebo-controlled interventional study. Sleep Science and Practice, 5 (1) 12, 12. doi: 10.1186/s41606-021-00065-3

An appraisal of trials investigating the effects on macular pigment optical density of lutein and zeaxanthin dietary interventions: a narrative review

Fitzpatrick, Naomi, Chachay, Veronique, Bowtell, Joanna, Jackman, Sarah, Capra, Sandra, Shore, Angela and Briskey, David (2021). An appraisal of trials investigating the effects on macular pigment optical density of lutein and zeaxanthin dietary interventions: a narrative review. Nutrition Reviews, 80 (3), 513-524. doi: 10.1093/nutrit/nuab038

The effect of an orally‐dosed Gynostemma pentaphyllum extract (ActivAMP®) on body composition in overweight, adult men and women: a double‐blind, randomised, placebo‐controlled study

Rao, Amanda, Clayton, Paul and Briskey, David (2021). The effect of an orally‐dosed Gynostemma pentaphyllum extract (ActivAMP®) on body composition in overweight, adult men and women: a double‐blind, randomised, placebo‐controlled study. Journal of Human Nutrition and Dietetics, 35 (3) jhn.12936, 583-589. doi: 10.1111/jhn.12936

Iron depletion attenuates steatosis in a mouse model of non-alcoholic fatty liver disease: Role of iron-dependent pathways

Crawford, Darrell H.G., Ross, Diana G.F., Jaskowski, Lesley-Anne, Burke, Leslie J., Britton, Laurence J., Musgrave, Nick, Briskey, David, Rishi, Gautam, Bridle, Kim R. and Subramaniam, V. Nathan (2021). Iron depletion attenuates steatosis in a mouse model of non-alcoholic fatty liver disease: Role of iron-dependent pathways. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1867 (7) 166142, 166142. doi: 10.1016/j.bbadis.2021.166142

Short duration alagebrium chloride therapy prediabetes does not inhibit progression to autoimmune diabetes in an experimental model

Borg, Danielle J., Faridi, Pouya, Giam, Kai Lin, Reeves, Peta, Fotheringham, Amelia K., McCarthy, Domenica A., Leung, Sherman, Ward, Micheal S., Harcourt, Brooke E., Ayala, Rochelle, Scheijen, Jean L., Briskey, David, Dudek, Nadine L., Schalkwijk, Casper G., Steptoe, Raymond, Purcell, Anthony W. and Forbes, Josephine M. (2021). Short duration alagebrium chloride therapy prediabetes does not inhibit progression to autoimmune diabetes in an experimental model. Metabolites, 11 (7) 426, 1-21. doi: 10.3390/metabo11070426

The effect of an orally-dosed Caralluma Fimbriata extract on appetite control and body composition in overweight adults

Rao, Amanda, Briskey, David, dos Reis, Carla and Mallard, Alistair R. (2021). The effect of an orally-dosed Caralluma Fimbriata extract on appetite control and body composition in overweight adults. Scientific Reports, 11 (1) 6791, 6791. doi: 10.1038/s41598-021-86108-2

Trans-resveratrol oral bioavailability in humans using lipisperse™ dispersion technology

Briskey, David and Rao, Amanda (2020). Trans-resveratrol oral bioavailability in humans using lipisperse™ dispersion technology. Pharmaceutics, 12 (12) 1190, 1-11. doi: 10.3390/pharmaceutics12121190

Reliability of a point-of-care device to determine oxidative stress in whole blood before and after acute exercise: A practical approach for the applied sports sciences

Quinn, Karlee M., Cox, Amanda J., Roberts, Llion A., Briskey, David and Minahan, Clare (2020). Reliability of a point-of-care device to determine oxidative stress in whole blood before and after acute exercise: A practical approach for the applied sports sciences. Journal of Sports Sciences, 39 (6), 1-10. doi: 10.1080/02640414.2020.1840755

Curcumin improves delayed onset muscle soreness and postexercise lactate accumulation

Mallard, Alistair R., Briskey, David, Richards, Andrew and Rao, Amanda (2020). Curcumin improves delayed onset muscle soreness and postexercise lactate accumulation. Journal of Dietary Supplements, 18 (5), 1-12. doi: 10.1080/19390211.2020.1796885

Inspiratory flow-resistive breathing, respiratory muscle-induced systemic oxidative stress, and diaphragm fatigue in healthy humans

Briskey, David R., Vogel, Kurt, Johnson, Michael A., Sharpe, Graham R., Coombes, Jeff S. and Mills, Dean E. (2020). Inspiratory flow-resistive breathing, respiratory muscle-induced systemic oxidative stress, and diaphragm fatigue in healthy humans. Journal of Applied Physiology, 129 (1), 185-193. doi: 10.1152/japplphysiol.00091.2020

Targeting the intestinal microbiota to prevent Type 2 Diabetes and enhance the effect of metformin on glycaemia: a randomised controlled pilot study

Palacios, Talia, Vitetta, Luis, Coulson, Samantha, Madigan, Claire D., Lam, Yan Y., Manuel, Rachel, Briskey, David, Hendy, Chelsea, Kim, Ji-Nu, Ishoey, Thomas, Soto-Giron, Maria J., Schott, Eric M., Toledo, Gerardo and Caterson, Ian D. (2020). Targeting the intestinal microbiota to prevent Type 2 Diabetes and enhance the effect of metformin on glycaemia: a randomised controlled pilot study. Nutrients, 12 (7) 2041, 2041-15. doi: 10.3390/nu12072041

The effect of orally dosed Levagen+™ (palmitoylethanolamide) on exercise recovery in healthy males—a double-blind, randomized, placebo-controlled study

Mallard, Alistair, Briskey, David, Richards, Andrew, Mills, Dean and Rao, Amanda (2020). The effect of orally dosed Levagen+™ (palmitoylethanolamide) on exercise recovery in healthy males—a double-blind, randomized, placebo-controlled study. Nutrients, 12 (3) 596, 1-13. doi: 10.3390/nu12030596

Bioaccessibility and pharmacokinetics of a commercial saffron (Crocus sativus L.) extract

Almodóvar, Paula, Briskey, David, Rao, Amanda, Prodanov, Marín and Inarejos-García, Antonio M. (2020). Bioaccessibility and pharmacokinetics of a commercial saffron (Crocus sativus L.) extract. Evidence-Based Complementary and Alternative Medicine, 2020 1575730, 1575730-8. doi: 10.1155/2020/1575730

Omega-3 eicosapentaenoic acid (Epa) rich extract from the microalga nannochloropsis decreases cholesterol in healthy individuals: A double-blind, randomized, placebo-controlled, three-month supplementation study

Rao, Amanda, Briskey, David, Nalley, Jakob O. and Ganuza, Eneko (2020). Omega-3 eicosapentaenoic acid (Epa) rich extract from the microalga nannochloropsis decreases cholesterol in healthy individuals: A double-blind, randomized, placebo-controlled, three-month supplementation study. Nutrients, 12 (6) 1869, 1-14. doi: 10.3390/nu12061869

A self-emulsifying Omega-3 ethyl ester formulation (AquaCelle) significantly improves eicosapentaenoic and docosahexaenoic acid bioavailability in healthy adults

Bremmell, Kristen E., Briskey, David, Meola, Tahlia R., Mallard, Alistair, Prestidge, Clive A. and Rao, Amanda (2019). A self-emulsifying Omega-3 ethyl ester formulation (AquaCelle) significantly improves eicosapentaenoic and docosahexaenoic acid bioavailability in healthy adults. European Journal of Nutrition, 59 (6), 2729-2737. doi: 10.1007/s00394-019-02118-x

The impact of micelle size and increased absorption of ubiquinone using a novel delivery system (AquaCelle®)

Briskey, David, Sax, Andrew T., Mallard, Alistair R., Ng, Charlie and Rao, Amanda (2019). The impact of micelle size and increased absorption of ubiquinone using a novel delivery system (AquaCelle®). International Journal of Pharmacokinetics, 5 (1) ipk-2019-0004, 1-10. doi: 10.4155/ipk-2019-0004

Increased bioavailability of curcumin using a novel dispersion technology system (LipiSperse®)

Briskey, D., Sax, A., Mallard, A. R. and Rao, A. (2018). Increased bioavailability of curcumin using a novel dispersion technology system (LipiSperse®). European Journal of Nutrition, 58 (5), 1-11. doi: 10.1007/s00394-018-1766-2

Acute Effects of Nitrate-Rich Beetroot Juice on Blood Pressure, Hemostasis and Vascular Inflammation Markers in Healthy Older Adults: A Randomized, Placebo-Controlled Crossover Study

Raubenheimer, Kyle, Hickey, Danica, Leveritt, Michael, Fassett, Robert, Ortiz de Zevallos Munoz, Joaquin, Allen, Jason D., Briskey, David, Parker, Tony J., Kerr, Graham, Peake, Jonathan M., Pecheniuk, Natalie M. and Neubauer, Oliver (2017). Acute Effects of Nitrate-Rich Beetroot Juice on Blood Pressure, Hemostasis and Vascular Inflammation Markers in Healthy Older Adults: A Randomized, Placebo-Controlled Crossover Study. Nutrients, 9 (11) 1270, 1-19. doi: 10.3390/nu9111270

Targeted mitochondrial therapy using MitoQ shows equivalent renoprotection to angiotensin converting enzyme inhibition but no combined synergy in diabetes

Ward, Micheal S.., Flemming, Nicole B., Gallo, Linda A., Fotheringham, Amelia K., McCarthy, Domenica A., Zhuang, Aowen, Tang, Peter H., Borg, Danielle J., Shaw, Hannah, Harvie, Benjamin, Briskey, David R., Roberts, Llion A., Plan, Manuel R., Murphy, Michael P., Hodson, Mark P. and Forbes, Josephine M. (2017). Targeted mitochondrial therapy using MitoQ shows equivalent renoprotection to angiotensin converting enzyme inhibition but no combined synergy in diabetes. Scientific Reports, 7 (1) 15190, 15190. doi: 10.1038/s41598-017-15589-x

Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice

Heritage, Mandy, Jaskowski, Lesley, Bridle, Kim, Campbell, Catherine, Briskey, David, Britton, Laurence, Fletcher, Linda, Vitetta, Luis, Subramaniam, V. Nathan and Crawford, Darrell (2017). Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice. World Journal of Gastrointestinal Pathophysiology, 8 (2), 67-76. doi: 10.4291/wjgp.v8.i2.67

Effects of exercise and lifestyle intervention on oxidative stress in chronic kidney disease

Small, David M., Beetham, Kassia S., Howden, Erin J., Briskey, David R., Johnson, David W., Isbel, Nicole M., Gobe, Glenda C. and Coombes, Jeff S. (2017). Effects of exercise and lifestyle intervention on oxidative stress in chronic kidney disease. Redox Report, 22 (3), 1-10. doi: 10.1080/13510002.2016.1276314

Oxidative stress, DNA Damage and DNA repair in female patients with diabetes mellitus type 2

Grindel, Annemarie, Guggenberger, Bianca, Eichberger, Lukas, Poppelmeyer, Christina, Gschaider, Michaela, Tosevska, Anela, Mare, George, Briskey, David, Brath, Helmut and Wagner, Karl-Heinz (2016). Oxidative stress, DNA Damage and DNA repair in female patients with diabetes mellitus type 2. PLoS ONE, 11 (9) e0162082, e0162082. doi: 10.1371/journal.pone.0162082

Microbiota and the nitrogen cycle: implications in the development and progression of CVD and CKD

Briskey, David, Tucker, Patrick S., Johnson, David W. and Coombes, Jeff S. (2016). Microbiota and the nitrogen cycle: implications in the development and progression of CVD and CKD. Nitric Oxide, 57, 64-70. doi: 10.1016/j.niox.2016.05.002

Probiotics modify tight-junction proteins in an animal model of nonalcoholic fatty liver disease

Briskey, David, Heritage, Mandy, Jaskowski, Lesley-Anne, Peake, Jonathan, Gobe, Glenda, Subramaniam, V. Nathan, Crawford, Darrell, Campbell, Catherine and Vitetta, Luis (2016). Probiotics modify tight-junction proteins in an animal model of nonalcoholic fatty liver disease. Therapeutic Advances in Gastroenterology, 9 (4), 463-472. doi: 10.1177/1756283X16645055

The role of the gastrointestinal tract and microbiota on uremic toxins and chronic kidney disease development

Briskey, David, Tucker, Patrick, Johnson, David W. and Coombes, Jeff S. (2016). The role of the gastrointestinal tract and microbiota on uremic toxins and chronic kidney disease development. Clinical and Experimental Nephrology, 21 (1), 1-9. doi: 10.1007/s10157-016-1255-y

High intensity interval training favourably affects antioxidant and inflammation mRNA expression in early-stage chronic kidney disease

Tucker, Patrick S., Briskey, David R., Scanlan, Aaron T., Coombes, Jeff S. and Dalbo, Vincent J. (2015). High intensity interval training favourably affects antioxidant and inflammation mRNA expression in early-stage chronic kidney disease. Free Radical Biology and Medicine, 89, 466-472. doi: 10.1016/j.freeradbiomed.2015.07.162

Endogenously elevated bilirubin modulates kidney function and protects from circulating oxidative stress in a rat model of adenine-induced kidney failure

Boon, Ai-Ching, Lam, Alfred K., Gopalan, Vinod, Benzie, Iris F., Briskey, David, Coombes, Jeff S., Fassett, Robert G. and Bulmer, Andrew C. (2015). Endogenously elevated bilirubin modulates kidney function and protects from circulating oxidative stress in a rat model of adenine-induced kidney failure. Scientific Reports, 5 (15482) 15482, 1-16. doi: 10.1038/srep15482

Glutathione depletion and acute exercise increase O-GlcNAc protein modification in rat skeletal muscle

Peternelj, Tina Tinkara, Marsh, Susan A., Strobel, Natalie A., Matsumoto, Aya, Briskey, David, Dalbo, Vincent J., Tucker, Patrick S. and Coombes, Jeff S. (2015). Glutathione depletion and acute exercise increase O-GlcNAc protein modification in rat skeletal muscle. Molecular and Cellular Biochemistry, 400 (1-2), 265-275. doi: 10.1007/s11010-014-2283-0

Oxidative stress contributes to muscle atrophy in chronic kidney disease patients

Beetham, Kassia S., Howden, Erin J., Small, David M., Briskey, David R., Rossi, Megan, Isbel, Nicole and Coombes, Jeff S. (2015). Oxidative stress contributes to muscle atrophy in chronic kidney disease patients. Redox Report, 20 (3), 126-132. doi: 10.1179/1351000214Y.0000000114

Altering the redox state of skeletal muscle by glutathione depletion increases the exercise-activation of PGC-1α

Strobel, Natalie A., Matsumoto, Aya, Peake, Jonathan M., Marsh, Susan A., Peternelj, Tina-Tinkara, Briskey, David, Fassett, Robert G., Coombes, Jeff S. and Wadley, Glenn D. (2014). Altering the redox state of skeletal muscle by glutathione depletion increases the exercise-activation of PGC-1α. Physiological Reports, 2 (12) e12224, 1-10. doi: 10.14814/phy2.12224

Probiotics, prebiotics and the gastrointestinal tract in health and disease

Vitetta, Luis, Briskey, David, Alford, Hollie, Hall, Sean and Coulson, Samantha (2014). Probiotics, prebiotics and the gastrointestinal tract in health and disease. Inflammopharmacology, 22 (3), 135-154. doi: 10.1007/s10787-014-0201-4

Optimized method for quantification of total F2-isoprostanes using gas chromatography–tandem mass spectrometry

Briskey, David R., Wilson, Gary R., Fassett, Robert G. and Coombes, Jeff S. (2014). Optimized method for quantification of total F2-isoprostanes using gas chromatography–tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 90, 161-166. doi: 10.1016/j.jpba.2013.11.028

Variability of oxidative stress biomarkers in hemodialysis patients

Dahwa, Rumbidzai, Fassett, Robert G., Wang, Zaimin, Briskey, David, Mallard, Alistair R. and Coombes, Jeff S. (2014). Variability of oxidative stress biomarkers in hemodialysis patients. Biomarkers, 19 (2), 154-158. doi: 10.3109/1354750X.2013.867533

Effects of probiotics supplementation on gastrointestinal permeability, inflammation and exercise performance in the heat

Shing, Cecilia M., Peake, Jonathan M., Lim, Chin Leong, Briskey, David, Walsh, Neil P., Fortes, Matthew B., Ahuja, Kiran D. K. and Vitetta, Luis (2013). Effects of probiotics supplementation on gastrointestinal permeability, inflammation and exercise performance in the heat. European Journal of Applied Physiology, Online First (1), 1-11. doi: 10.1007/s00421-013-2748-y

Variability in oxidative stress biomarkers following a maximal exercise test

Mullins, Anna L., van Rosendal, Simon P., Briskey, David R., Fassett, Robert G., Wilson, Gary R. and Coombes, Jeff S. (2013). Variability in oxidative stress biomarkers following a maximal exercise test. Biomarkers, 18 (5), 446-454. doi: 10.3109/1354750X.2013.810668

Postprandial total and HMW adiponectin following a high-fat meal in lean, obese and diabetic men

Phillips, L. K., Peake, J. M., Zhang, X., Hickman, I. J., Briskey, D. R., Huang, B. E., Simpson, P., Li, S-H, Whitehead, J. P., Martin, J. H. and Prins, J. B. (2013). Postprandial total and HMW adiponectin following a high-fat meal in lean, obese and diabetic men. European Journal of Clinical Nutrition, 67 (4), 377-384. doi: 10.1038/ejcn.2013.49

A review of the pharmacobiotic regulation of gastrointestinal inflammation by probiotics, commensal bacteria and prebiotics

Vitetta, L, Briskey, D., Hayes, E., Shing, C. and Peake, J. (2012). A review of the pharmacobiotic regulation of gastrointestinal inflammation by probiotics, commensal bacteria and prebiotics. Inflammopharmacology, 20 (5), 251-266. doi: 10.1007/s10787-012-0126-8

Far-infrared Emitting Fabric Improves Aerobic Metabolism, Oxidative Stress and Exercise Tolerance, Independent of Nitric Oxide

Gaspari, Arthur, de Moraes, Antonio Carlos, Bernardes, Celene, Barbieri, Joao, Guimaraes, Patricia, Sardeli, Amanda, Castro, Alex, Sposito, Andrei, McConell, Glenn, Briskey, David, Chacon-Mikahil, Mara Patricia and Bertuzzi, Romulo (2017). Far-infrared Emitting Fabric Improves Aerobic Metabolism, Oxidative Stress and Exercise Tolerance, Independent of Nitric Oxide. Annual Meeting of the American-College-of-Sports-Medicine (ACSM), Denver CO, United States, May 30-Jun 03, 2017. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1249/01.mss.0000519556.28743.07

Inspiratory Flow Resistive Loaded Breathing and Inspiratory Muscle Induced Systemic Oxidative Stress

Mills, Dean E., Vogel, Kurt, Johnson, Michael A., Sharpe, Graham R., Coombes, Jeff S. and Briskey, David R. (2017). Inspiratory Flow Resistive Loaded Breathing and Inspiratory Muscle Induced Systemic Oxidative Stress. Annual Meeting of the American-College-of-Sports-Medicine (ACSM), Denver CO, United States, May 30-Jun 03, 2017. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1249/01.mss.0000516852.35352.1d

Oxidative stress is associated with poor grip strength and sarcopenia in patients with chronic kidney disease

Weston, K., Howden, E., Briskey, D., Isbel, N. and Coombes, J. (2013). Oxidative stress is associated with poor grip strength and sarcopenia in patients with chronic kidney disease. 49th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Brisbane, QLD, Australia, 9-11 September 2013. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/nep.12121

Lutein and zeaxanthin dietary screeners validation study in healthy Australian and United Kingdom adults

Fitzpatrick, Naomi, Chachay, Veronique, Capra, Sandra, Jackman, S.R. and Briskey, David (2023). Lutein and zeaxanthin dietary screeners validation study in healthy Australian and United Kingdom adults. The University of Queensland. (Dataset) doi: 10.48610/f9416b1

Development and validity evaluation of an electronic device use questionnaire in Australian and United Kingdom adults

Fitzpatrick, Naomi, Chachay, Veronique, Capra, Sandra, S.R.Jackman and Briskey, David (2023). Development and validity evaluation of an electronic device use questionnaire in Australian and United Kingdom adults. The University of Queensland. (Dataset) doi: 10.48610/61b97b1

The effects of multi-strain probiotics on liver disease

Briskey, David (2015). The effects of multi-strain probiotics on liver disease. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/uql.2015.290