Dr Melissa Lai is a Neonatologist at the Grantley Stable Neonatal Unit, Royal Brisbane and Women's Hospital, and serves as co-chair of the RBWH Neonatal Research Group. She is the site lead for a dynamic set of clinical trials and quality improvement projects, and helps to build research capacity and collaboration across institutions. Awarded in 2021, Dr Lai's PhD investigated the neurodevelopmental effects of infant massage in premature infants with a primary outcome measuring neonatal EEG power. Other clinical areas of interest include data management, clinician performed ultrasound and retrieval coordination. She is currently building an innovative body of work related to improving and supporting the provision of mother's own milk, and introducing new technologies into the neonatal intensive care environment.
Journal Article: Outcomes and perspectives of woman-newborn dyads following discharge from a quaternary maternity service in Australia: a cross-sectional survey
Lai, Melissa M., August, Deanne, Sharfuddin, Zoya, Palmer-Field, Kristina, Johnston, Louise, Main, Elizabeth, Smith, Patricia, Kilgour, Catherine M. and Kearney, Lauren (2024). Outcomes and perspectives of woman-newborn dyads following discharge from a quaternary maternity service in Australia: a cross-sectional survey. Women and Birth, 37 (1), 248-256. doi: 10.1016/j.wombi.2023.10.007
Journal Article: Period prevalence of positional head deformations and implications for practice in a large tertiary neonatal unit
Hepnar, Lindsay, Ngenda, Naoni, Cottrell, Michelle, Lai, Melissa, Sharpe, Janet and August, Deanne (2023). Period prevalence of positional head deformations and implications for practice in a large tertiary neonatal unit. Journal of Paediatrics and Child Health, 60 (1), 18-23. doi: 10.1111/jpc.16520
Journal Article: Subpial haemorrhage in a well-term neonate
Hong, Lisa, McLaughlin, Linda, Lai, Melissa and Guandalini, Michael (2023). Subpial haemorrhage in a well-term neonate. Journal of Paediatrics and Child Health, 59 (5), 766-768. doi: 10.1111/jpc.16394
Does plasma protein fetuin protect the injured newborn brain?
(2019–2020) Metro North Hospital and Health Service
CO2 gas as adjunctive neuroprotective therapy for hypoxic ischaemic encephalopathy (HIE)
(2018) Metro North Hospital and Health Service
Stem cell treatment to protect the growth restricted newborn brain
(2018) Metro North Hospital and Health Service
Lai, Melissa M., August, Deanne, Sharfuddin, Zoya, Palmer-Field, Kristina, Johnston, Louise, Main, Elizabeth, Smith, Patricia, Kilgour, Catherine M. and Kearney, Lauren (2024). Outcomes and perspectives of woman-newborn dyads following discharge from a quaternary maternity service in Australia: a cross-sectional survey. Women and Birth, 37 (1), 248-256. doi: 10.1016/j.wombi.2023.10.007
Hepnar, Lindsay, Ngenda, Naoni, Cottrell, Michelle, Lai, Melissa, Sharpe, Janet and August, Deanne (2023). Period prevalence of positional head deformations and implications for practice in a large tertiary neonatal unit. Journal of Paediatrics and Child Health, 60 (1), 18-23. doi: 10.1111/jpc.16520
Subpial haemorrhage in a well-term neonate
Hong, Lisa, McLaughlin, Linda, Lai, Melissa and Guandalini, Michael (2023). Subpial haemorrhage in a well-term neonate. Journal of Paediatrics and Child Health, 59 (5), 766-768. doi: 10.1111/jpc.16394
Infant massage and brain maturation measured using EEG: A randomised controlled trial
Lai, Melissa, D'Acunto, Giulia, Guzzetta, Andrea, Finnigan, Simon, Ngenda, Naoni, Ware, Robert S., Boyd, Roslyn N. and Colditz, Paul B. (2022). Infant massage and brain maturation measured using EEG: A randomised controlled trial. Early Human Development, 172 105632, 1-8. doi: 10.1016/j.earlhumdev.2022.105632
Determining reference data for overnight oximetry in neonates: a pilot study
Flint, Anndrea, August, Deanne, Lai, Melissa, Chawla, Jasneek, Ballard, Emma and Davies, Mark W. (2022). Determining reference data for overnight oximetry in neonates: a pilot study. Early Human Development, 168 105571, 1-5. doi: 10.1016/j.earlhumdev.2022.105571
Epidemiology and long-term neurological sequelae of childhood herpes simplex CNS infection
Berkhout, Angela, Kapoor, Vishal, Heney, Claire, Jones, Cheryl A., Clark, Julia E., Britton, Philip N., Vaska, Vikram L., Lai, Melissa M. and Nourse, Clare (2022). Epidemiology and long-term neurological sequelae of childhood herpes simplex CNS infection. Journal of Paediatrics and Child Health, 58 (8), 1372-1378. doi: 10.1111/jpc.15992
Electroencephalographic studies in growth-restricted and small-for-gestational-age neonates
Stevenson, Nathan J., Lai, Melissa M., Starkman, Hava E., Colditz, Paul B. and Wixey, Julie A. (2022). Electroencephalographic studies in growth-restricted and small-for-gestational-age neonates. Pediatric Research, 92 (6), 1-8. doi: 10.1038/s41390-022-01992-2
Neonatal early‐onset sepsis calculator safety in an Australian tertiary perinatal centre
Scott, Philip A., Lai, Melissa, Inglis, Garry D. T. and Davies, Mark W. (2022). Neonatal early‐onset sepsis calculator safety in an Australian tertiary perinatal centre. Journal of Paediatrics and Child Health, 58 (5), 863-867. doi: 10.1111/jpc.15860
Berkhout, Angela, Kapoor, Vishal, Heney, Claire, Jones, Cheryl A., Clark, Julia E., Vaska, Vikram L., Lai, Melissa and Nourse, Clare (2021). Herpes Simplex Virus Infection in Infants: 13 Year Evaluation (2005-2017) of Laboratory Confirmed Cases in Queensland, Australia. Pediatric Infectious Disease Journal, 40 (3) 002970, 209-214. doi: 10.1097/INF.0000000000002970
Kong, Annice H.T., Lai, Melissa M., Finnigan, Simon, Ware, Robert S., Boyd, Roslyn N. and Colditz, Paul B. (2018). Background EEG features and prediction of cognitive outcomes in very preterm infants: a systematic review. Early Human Development, 127, 74-84. doi: 10.1016/j.earlhumdev.2018.09.015
Lai, Melissa M., D'Acunto, Giulia, Guzzetta, Andrea, Boyd, Roslyn N., Rose, Stephen E., Fripp, Jurgen, Finnigan, Simon, Ngenda, Naoni, Love, Penny, Whittingham, Koa, Pannek, Kerstin, Ware, Robert S. and Colditz, Paul B. (2016). PREMM: preterm early massage by the mother: protocol of a randomised controlled trial of massage therapy in very preterm infants. BMC Pediatrics, 16 (146) 146, 1-12. doi: 10.1186/s12887-016-0678-7
George, Joanne M., Boyd, Roslyn N., Colditz, Paul B., Rose, Stephen E., Pannek, Kerstin, Fripp, Jurgen, Lingwood, Barbara E., Lai, Melissa M., Kong, Annice HT., Ware, Robert S., Coulthard, Alan, Finn, Christine M. and Bandaranayake, Sasaka E. (2015). PPREMO: A prospective cohort study of preterm infant brain structure and function to predict neurodevelopmental outcome. BMC Pediatrics, 15 (123) 123, 123. doi: 10.1186/s12887-015-0439-z
Awal, Md. Abdul, Lai, Melissa M., Azemi, Ghasem, Boashash, Boualem and Colditz, Paul B. (2015). EEG background features that predict outcome in term neonates with hypoxic ischaemic encephalopathy: a structured review. Clinical Neurophysiology, 127 (1), 285-296. doi: 10.1016/j.clinph.2015.05.018
Subgaleal haemorrhage in the newborn: a call for early diagnosis and aggressive management
Colditz, Michael J., Lai, Melissa M., Cartwright, David W. and Colditz, Paul B. (2014). Subgaleal haemorrhage in the newborn: a call for early diagnosis and aggressive management. Journal of Paediatrics and Child Health, 51 (2), 140-146. doi: 10.1111/jpc.12698
Methods for securing endotracheal tubes in newborn infants (Review)
Lai, Melissa, Inglis, Garry D. T., Hose, Karen, Jardine, Luke A. and Davies, Mark W. (2014). Methods for securing endotracheal tubes in newborn infants (Review). The Cochrane database of systematic reviews, 2014 (7) CD007805. doi: 10.1002/14651858.CD007805.pub2
Methods for securing endotracheal tubes in newborn infants (Protocol)
Lai, Melissa, Inglis, Garry D. T., Hose, Karen, Jardine, Luke A. and Davies, Mark W. (2009). Methods for securing endotracheal tubes in newborn infants (Protocol). Cochrane Database of Systematic Reviews, 1 (2) CD007805, 165-168. doi: 10.1002/14651858.CD007805
Lai, Melissa (2021). Towards Optimising Neurodevelopment in very preterm infants: the effects of infant massage by the mother. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/6a534e0
Does plasma protein fetuin protect the injured newborn brain?
(2019–2020) Metro North Hospital and Health Service
CO2 gas as adjunctive neuroprotective therapy for hypoxic ischaemic encephalopathy (HIE)
(2018) Metro North Hospital and Health Service
Stem cell treatment to protect the growth restricted newborn brain
(2018) Metro North Hospital and Health Service
Protecting growth restricted newborn brains by reducing inflammation
(2016–2017) Royal Brisbane and Women's Hospital Foundation
Defining the mechanisms of hypothermic neuroprotection in the HIE newborn
(2015) Royal Brisbane and Women's Hospital