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Reaching new heights in high-resolution electron microscopy (2015–2016)

Abstract:
Direct Electron Detection cameras are a recent technological breakthrough delivering one of the greatest single advancements to the field of molecular cryo-EM. The aim of this proposal is to enable a "first of a kind" cryo-EM platform in Australia enabling high-throughput atomic resolution protein structure determination. This will be achieved by integrating a state-of-the-art Gatan K2 Summit Direct Electron Detection camera system into the established ~$15M cryo-EM facility managed by the UQ node of the Australian Microscopy & Microanalysis Facility. This will offer unique and significantly improved capabilities for atomic resolution protein structure analysis, and will support a broad range of projects across the biological sciences.
Grant type:
ARC Linkage Infrastructure, Equipment and Facilities
Researchers:

  • Professor Ben Hankamer

    Professorial Research Fellow
    Institute for Molecular Bioscience
    Professorial Research Fellow
    Institute for Molecular Bioscience
    Affiliate Professor of School of Ch
    School of Chemistry and Molecular Biosciences
    Faculty of Science

  • Associate Professor Michael Landsberg

    Associate Professor
    School of Chemistry and Molecular Biosciences
    Faculty of Science
    Affiliate Associate Professor
    Institute for Molecular Bioscience
    Affiliate of ARC COE for Innovation
    ARC Centre of Excellence for Innovations in Peptide and Protein Science
    Institute for Molecular Bioscience

  • Professor Robert Parton

    ARC Laureate Fellow - Group Leader
    Institute for Molecular Bioscience
    ARC Laureate Fellow - Group Leader
    Institute for Molecular Bioscience
    Affiliate Professor
    School of Biomedical Sciences
    Faculty of Medicine

  • Professor Paul Young

    Professor, Research Development
    Office of the Deputy Vice-Chancellor (Research and Innovation)
    Professor, Research Development
    Office of the Deputy Vice-Chancellor (Research and Innovation)
    Affiliate Professor
    Australian Institute for Bioengineering and Nanotechnology

  • Professor Michael Monteiro

    Senior Group Leader
    Australian Institute for Bioengineering and Nanotechnology
    Professor
    School of Chemistry and Molecular Biosciences
    Faculty of Science
Funded by:
Australian Research Council