The University of Queensland

Protease Activated Receptor 2 : A New Drug Target For Inflammatory Diseases and Cancer (2009–2012)

Abstract:

A new class of proteins (Protease Activated Receptors) has been found on the surfaces of many different types of cells. They are believed to be natural sensors that respond to traces of degradative enzymes called proteases. This project will create and evaluate new drugs for one of these receptors thought to regulate inflammatory diseases (e.g. arthritis, inflammatory bowel disease, asthma, pancreatitis) and cancers, while providing a better understanding of a new mechanism of immune defence.

Grant type:

NHMRC Project Grant

Researchers:

• 

  Professor David Fairlie

  NHMRC Leadership Fellow and Group L
  

  Institute for Molecular Bioscience

• 

  Associate Professor David Vesey

  ATH - Associate Professor
  

  Princess Alexandra Hospital Southside Clinical Unit

  Faculty of Medicine

Funded by:

National Health and Medical Research Council