The University of Queensland

BoNT-A Targets Sensitized TRPV1-Positive DRG Neurons at Therapeutic Concentrations

Syed, Parnayan, Gormal, Rachel S., Sondergaard, Birgitte, Nelson, Mariana, Broide, Ron S. and Meunier, Frédéric A. (2024). BoNT-A Targets Sensitized TRPV1-Positive DRG Neurons at Therapeutic Concentrations. Toxicon, 237 107497, 107497. doi: 10.1016/j.toxicon.2024.107497

Presynaptic targeting of botulinum neurotoxin type A requires a tripartite PSG‐Syt1 ‐ SV2 plasma membrane nanocluster for synaptic vesicle entry

Joensuu, Merja, Syed, Parnayan, Saber, Saber H., Lanoue, Vanessa, Wallis, Tristan P., Rae, James, Blum, Ailisa, Gormal, Rachel S., Small, Christopher, Sanders, Shanley, Jiang, Anmin, Mahrhold, Stefan, Krez, Nadja, Cousin, Michael A., Cooper‐White, Ruby, Cooper‐White, Justin J., Collins, Brett M., Parton, Robert G., Balistreri, Giuseppe, Rummel, Andreas and Meunier, Frédéric A. (2023). Presynaptic targeting of botulinum neurotoxin type A requires a tripartite PSG‐Syt1 ‐ SV2 plasma membrane nanocluster for synaptic vesicle entry. The EMBO Journal, 42 (13) e112095, e112095. doi: 10.15252/embj.2022112095

Ancestral sequence reconstruction of a cytochrome P450 family involved in chemical defense reveals the functional evolution of a promiscuous, xenobiotic-metabolizing enzyme in vertebrates

Harris, Kurt L., Thomson, Raine E.S., Gumulya, Yosephine, Foley, Gabriel, Carrera-Pacheco, Saskya E., Syed, Parnayan, Janosik, Tomasz, Sandinge, Ann-Sofie, Andersson, Shalini, Jurva, Ulrik, Bodén, Mikael and Gillam, Elizabeth M.J. (2022). Ancestral sequence reconstruction of a cytochrome P450 family involved in chemical defense reveals the functional evolution of a promiscuous, xenobiotic-metabolizing enzyme in vertebrates. Molecular Biology and Evolution, 39 (6) msac116. doi: 10.1093/molbev/msac116

Effects of GABA(A) Receptor alpha 3 Subunit Epilepsy Mutations on Inhibitory Synaptic Signaling

Syed, Parnayan, Durisic, Nela, Harvey, Robert J., Sah, Pankaj and Lynch, Joseph W. (2020). Effects of GABA(A) Receptor alpha 3 Subunit Epilepsy Mutations on Inhibitory Synaptic Signaling. Frontiers in Molecular Neuroscience, 13 602559, 602559. doi: 10.3389/fnmol.2020.602559

Structure/Function Studies of the alpha 4 Subunit Reveal Evolutionary Loss of a GlyR Subtype Involved in Startle and Escape Responses

Leacock, Sophie, Syed, Parnayan, James, Victoria M., Bode, Anna, Kawakami, Koichi, Keramidas, Angelo, Suster, Maximiliano, Lynch, Joseph W. and Harvey, Robert J. (2018). Structure/Function Studies of the alpha 4 Subunit Reveal Evolutionary Loss of a GlyR Subtype Involved in Startle and Escape Responses. Frontiers in Molecular Neuroscience, 11 23, 23. doi: 10.3389/fnmol.2018.00023

The role of GABA receptors in synaptic plasticity and disease

Syed, Parnayan (2023). The role of GABA receptors in synaptic plasticity and disease. PhD Thesis, Queensland Brain Institute, The University of Queensland. doi: 10.14264/49f7b7a