The University of Queensland

Using the evolutionary history of proteins to engineer insertion-deletion mutants from robust, ancestral templates using Graphical Representation of Ancestral Sequence Predictions (GRASP)

Ross, Connie M., Foley, Gabriel, Boden, Mikael and Gillam, Elizabeth M. J. (2022). Using the evolutionary history of proteins to engineer insertion-deletion mutants from robust, ancestral templates using Graphical Representation of Ancestral Sequence Predictions (GRASP). Enzyme engineering. (pp. 85-110) edited by Francesca Magnani, Chiara Marabelli and Francesca Paradisi. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-1826-4_6

Quantifying caspase-1 activity in murine macrophages

Boucher, Dave, Chan, Amy, Ross, Connie and Schroder, Kate (2018). Quantifying caspase-1 activity in murine macrophages. Inflammation and cancer. (pp. 163-176) edited by Brendan J. Jenkins. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-7568-6_14

NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome

Coombs, Jared R., Zamoshnikova, Alina, Holley, Caroline L., Maddugoda, Madhavi P., Teo, Daniel Eng Thiam, Chauvin, Camille, Poulin, Lionel F, Vitak, Nazarii, Ross, Connie M., Mellacheruvu, Manasa, Coll, Rebecca C., Heinz, Leonhard X., Burgener, Sabrina S., Emming, Stefan, Chamaillard, Mathias, Boucher, Dave and Schroder, Kate (2024). NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome. Science Signaling, 17 (820) abg8145, eabg8145. doi: 10.1126/scisignal.abg8145

Engineering indel and substitution variants of diverse and ancient enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP)

Foley, Gabriel, Mora, Ariane, Ross, Connie M., Bottoms, Scott, Sützl, Leander, Lamprecht, Marnie L., Zaugg, Julian, Essebier, Alexandra, Balderson, Brad, Newell, Rhys, Thomson, Raine E. S., Kobe, Bostjan, Barnard, Ross T., Guddat, Luke, Schenk, Gerhard, Carsten, Jörg, Gumulya, Yosephine, Rost, Burkhard, Haltrich, Dietmar, Sieber, Volker, Gillam, Elizabeth M. J. and Bodén, Mikael (2022). Engineering indel and substitution variants of diverse and ancient enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP). PL o S Computational Biology, 18 (10) e1010633, e1010633. doi: 10.1371/journal.pcbi.1010633

Inflammatory caspases: toward a unified model for caspase activation by inflammasomes

Ross, Connie, Chan, Amy H., von Pein, Jessica B., Maddugoda, Madhavi P., Boucher, Dave and Schroder, Kate (2022). Inflammatory caspases: toward a unified model for caspase activation by inflammasomes. Annual Review of Immunology, 40 (1), 249-269. doi: 10.1146/annurev-immunol-101220-030653

Dimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasome

Ross, Connie, Chan, Amy H., Von Pein, Jessica, Boucher, Dave and Schroder, Kate (2018). Dimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasome. Life Science Alliance, 1 (6) e201800237, e201800237. doi: 10.26508/lsa.201800237

Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity

Boucher, Dave, Monteleone, Mercedes, Coll, Rebecca C., Chen, Kaiwen W., Ross, Connie M., Teo, Jessica L., Gomez, Guillermo A., Holley, Caroline L., Bierschenk, Damien, Stacey, Katryn J., Yap, Alpha S., Bezbradica, Jelena S. and Schroder, Kate (2018). Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity. The Journal of Experimental Medicine, 215 (3), 827-840. doi: 10.1084/jem.20172222

Ancestral reconstruction and characterisation of the CYP2U subfamily

Petroeschevsky, Connie Mae (2022). Ancestral reconstruction and characterisation of the CYP2U subfamily. PhD Thesis, Faculty of Science, The University of Queensland. doi: 10.14264/1d1eddc