Postdoctoral Research Fellow
Overview
Ram is a biologist who is engaged in research at the convergence of material science and biology. His primary area of research centers on the utilization of snake venom proteins to facilitate wound healing, specifically in the context of advancing bleeding control methodologies. His work aims to produce next generation biomaterials, with the ultimate goal of enhancing regenerative wound healing for individuals afflicted by burns and traumatic injuries.
Ram obtained his Bachelor of Technology (B.Tech) in Genetic Engineering from India's SRM Institute of Science and Technology (2015). His Bachelors dissertation was at Texas A&M University, US, focusing on hydrogel microparticles via sequential click reactions. He was a visiting researcher at the University of South Australia (2015-2016), exploring Diels-Alder click reaction kinetics for bioconjugation. He then obtained Master of Technology (M.Tech) in Nanomedical Sciences from India's Amrita Centre for Nanosciences and Molecular Medicine (2018), backed by Department of Science and Technology's 'Nanomission' scholarship. Ram undertook varied projects, involving ceramic and polymeric nanoparticles with hydrogels for bone tissue engineering, completing his PhD in 2023 at the University of Queensland's Australian Institute for Bioengineering and Nanotechnology where he investigated the application of snake venom proteins' potential in wound management.
Qualifications
- Doctoral (Research) of Bioengineering, The University of Queensland
- Masters (Research) of Nanomedicine
- Bachelor of Genetics
Publications
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Other Outputs: Understanding the science and application of snake venom proteins in wound management
Ramanathan Yegappan, Ramanathan (2023). Understanding the science and application of snake venom proteins in wound management. PhD Thesis, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland. doi: 10.14264/0751854
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Book Chapter: Carrageenan in tissue engineering and biomedical applications
Selvaprithiviraj, Vignesh, Yegappan, Ramanathan and Muthuswamy, Shiva (2023). Carrageenan in tissue engineering and biomedical applications. Natural biopolymers in drug delivery and tissue engineering. (pp. 449-480) edited by Rangasamy Jayakumar and Vishnu Priya Murali. Cambridge, MA United States: Woodhead Publishing. doi: 10.1016/b978-0-323-98827-8.00010-2
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Journal Article: Snake venom-defined fibrin architecture dictates fibroblast survival and differentiation
Wang, Zhao, Lauko, Jan, Kijas, Amanda W., Gilbert, Elliot P., Turunen, Petri, Yegappan, Ramanathan, Zou, Dongxiu, Mata, Jitendra and Rowan, Alan E. (2023). Snake venom-defined fibrin architecture dictates fibroblast survival and differentiation. Nature Communications, 14 (1) 1029, 1-16. doi: 10.1038/s41467-023-36437-9
Publications
Book Chapter
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Carrageenan in tissue engineering and biomedical applications
Selvaprithiviraj, Vignesh, Yegappan, Ramanathan and Muthuswamy, Shiva (2023). Carrageenan in tissue engineering and biomedical applications. Natural biopolymers in drug delivery and tissue engineering. (pp. 449-480) edited by Rangasamy Jayakumar and Vishnu Priya Murali. Cambridge, MA United States: Woodhead Publishing. doi: 10.1016/b978-0-323-98827-8.00010-2
Journal Article
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Snake venom-defined fibrin architecture dictates fibroblast survival and differentiation
Wang, Zhao, Lauko, Jan, Kijas, Amanda W., Gilbert, Elliot P., Turunen, Petri, Yegappan, Ramanathan, Zou, Dongxiu, Mata, Jitendra and Rowan, Alan E. (2023). Snake venom-defined fibrin architecture dictates fibroblast survival and differentiation. Nature Communications, 14 (1) 1029, 1-16. doi: 10.1038/s41467-023-36437-9
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Snake venom hydrogels as a rapid hemostatic agent for uncontrolled bleeding
Yegappan, Ramanathan, Lauko, Jan, Wang, Zhao, Lavin, Martin F., Kijas, Amanda W. and Rowan, Alan E. (2022). Snake venom hydrogels as a rapid hemostatic agent for uncontrolled bleeding. Advanced Healthcare Materials, 11 (15) 2200574, 2200574. doi: 10.1002/adhm.202200574
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Yegappan, Ramanathan, Selvaprithiviraj, Vignesh, Mohandas, Annapoorna and Jayakumar, Rangasamy (2019). Nano polydopamine crosslinked thiol-functionalized hyaluronic acid hydrogel for angiogenic drug delivery. Colloids and Surfaces B-Biointerfaces, 177, 41-49. doi: 10.1016/j.colsurfb.2019.01.035
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Injectable angiogenic and osteogenic carrageenan nanocomposite hydrogel for bone tissue engineering
Yegappan, Ramanathan, Selvaprithiviraj, Vignesh, Amirthalingam, Sivashanmugam, Mohandas, Annapoorna, Hwang, Nathaniel S. and Jayakumar, R. (2019). Injectable angiogenic and osteogenic carrageenan nanocomposite hydrogel for bone tissue engineering. International Journal of Biological Macromolecules, 122, 320-328. doi: 10.1016/j.ijbiomac.2018.10.182
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Muthuswamy, Shiva, Viswanathan, Aparna, Yegappan, Ramanathan, Selvaprithiviraj, Vignesh, Vasudevan, Anil Kumar, Biswas, Raja and Jayakumar, Rangasamy (2019). Antistaphylococcal and neutrophil chemotactic injectable κ-carrageenan hydrogel for infectious wound healing. ACS Applied Bio Materials, 2 (1), 378-387. doi: 10.1021/acsabm.8b00625
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Carrageenan based hydrogels for drug delivery, tissue engineering and wound healing
Yegappan, Ramanathan, Selvaprithiviraj, Vignesh, Amirthalingam, Sivashanmugam and Jayakumar, R. (2018). Carrageenan based hydrogels for drug delivery, tissue engineering and wound healing. Carbohydrate Polymers, 198, 385-400. doi: 10.1016/j.carbpol.2018.06.086
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Jivan, Faraz, Yegappan, Ramanathan, Pearce, Hannah, Carrow, James K., McShane, Michael, Gaharwar, Akhilesh K. and Alge, Daniel L. (2016). Sequential thiol-ene and tetrazine click reactions for the polymerization and functionalization of hydrogel microparticles. Biomacromolecules, 17 (11), 3516-3523. doi: 10.1021/acs.biomac.6b00990
Other Outputs
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Understanding the science and application of snake venom proteins in wound management
Ramanathan Yegappan, Ramanathan (2023). Understanding the science and application of snake venom proteins in wound management. PhD Thesis, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland. doi: 10.14264/0751854
