The University of Queensland

FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors

Nguyen‐Dien, Giang Thanh, Kozul, Keri‐Lyn, Cui, Yi, Townsend, Brendan, Kulkarni, Prajakta Gosavi, Ooi, Soo Siang, Marzio, Antonio, Carrodus, Nissa, Zuryn, Steven, Pagano, Michele, Parton, Robert G, Lazarou, Michael, Millard, S Sean, Taylor, Robert W, Collins, Brett M, Jones, Mathew JK and Pagan, Julia K (2023). FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors. The EMBO Journal, 42 (13) e112767, e112767. doi: 10.15252/embj.2022112767

Form and function of the Golgi apparatus: scaffolds, cytoskeleton and signalling

Kulkarni‐Gosavi, Prajakta, Makhoul, Christian and Gleeson, Paul A. (2019). Form and function of the Golgi apparatus: scaffolds, cytoskeleton and signalling. FEBS Letters, 593 (17), 2289-2305. doi: 10.1002/1873-3468.13567

The Golgi ribbon in mammalian cells negatively regulates autophagy by modulating mTOR activity

Gosavi, Prajakta, Houghton, Fiona J., McMillan, Paul J., Hanssen, Eric and Gleeson, Paul A. (2018). The Golgi ribbon in mammalian cells negatively regulates autophagy by modulating mTOR activity. Journal of Cell Science, 131 (3), 1-15. doi: 10.1242/jcs.211987

The Function of the Golgi Ribbon Structure – An Enduring Mystery Unfolds!

Gosavi, Prajakta and Gleeson, Paul A. (2017). The Function of the Golgi Ribbon Structure – An Enduring Mystery Unfolds!. BioEssays, 39 (11) 1700063, 1-9. doi: 10.1002/bies.201700063

E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly

Gosavi, Prajakta, Kundu, Samrat T., Khapare, Nileema, Sehgal, Lalit, Karkhanis, Mansi S. and Dalal, Sorab N. (2010). E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly. Cellular and Molecular Life Sciences, 68 (8), 1439-1454. doi: 10.1007/s00018-010-0531-3

FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors

Nguyen‐Dien, Giang Thanh, Kozul, Keri‐Lyn, Cui, Yi, Townsend, Brendan, Kulkarni, Prajakta Gosavi, Ooi, Soo Siang, Marzio, Antonio, Carrodus, Nissa, Zuryn, Steven, Pagano, Michele, Parton, Robert G, Lazarou, Michael, Millard, S Sean, Taylor, Robert W, Collins, Brett M, Jones, Mathew JK and Pagan, Julia K (2023). FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors. The EMBO Journal, 42 (13) e112767, e112767. doi: 10.15252/embj.2022112767

A role for Rab30 in retrograde trafficking and maintenance of endosome-TGN organization

Zulkefli, Khalisah L., Mahmoud, Ismail S., Williamson, Nicholas A., Gosavi, Prajakta Kulkarni, Houghton, Fiona J. and Gleeson, Paul A. (2021). A role for Rab30 in retrograde trafficking and maintenance of endosome-TGN organization. Experimental Cell Research, 399 (2) 112442, 112442. doi: 10.1016/j.yexcr.2020.112442

Form and function of the Golgi apparatus: scaffolds, cytoskeleton and signalling

Kulkarni‐Gosavi, Prajakta, Makhoul, Christian and Gleeson, Paul A. (2019). Form and function of the Golgi apparatus: scaffolds, cytoskeleton and signalling. FEBS Letters, 593 (17), 2289-2305. doi: 10.1002/1873-3468.13567

Golgi dynamics: The morphology of the mammalian Golgi apparatus in health and disease

Makhoul, Christian, Gosavi, Prajakta and Gleeson, Paul A. (2019). Golgi dynamics: The morphology of the mammalian Golgi apparatus in health and disease. Frontiers in Cell and Developmental Biology, 7, 1-7. doi: 10.3389/fcell.2019.00112

A role for Rab11 in the homeostasis of the endosome-lysosomal pathway

Zulkefli, Khalisah L., Houghton, Fiona J., Gosavi, Prajakta and Gleeson, Paul A. (2019). A role for Rab11 in the homeostasis of the endosome-lysosomal pathway. Experimental Cell Research, 380 (1), 55-68. doi: 10.1016/j.yexcr.2019.04.010

Intersectin-1 interacts with the golgin GCC88 to couple the actin network and Golgi architecture

Makhoul, Christian, Gosavi, Prajakta, Duffield, Regina, Delbridge, Bronwen, Williamson, Nicholas A. and Gleeson, Paul A. (2019). Intersectin-1 interacts with the golgin GCC88 to couple the actin network and Golgi architecture. Molecular Biology of the Cell, 30 (3), 370-386. doi: 10.1091/mbc.e18-05-0313

The Golgi architecture and cell sensing

Makhoul, Christian, Gosavi, Prajakta and Gleeson, Paul A. (2018). The Golgi architecture and cell sensing. Biochemical Society Transactions, 46 (5), 1063-1072. doi: 10.1042/bst20180323

First person - Prajakta Gosavi

Gosavi, Prajakta (2018). First person - Prajakta Gosavi. Journal of Cell Science, 131 (3), 1-2. doi: 10.1242/jcs.215640

The Golgi ribbon in mammalian cells negatively regulates autophagy by modulating mTOR activity

Gosavi, Prajakta, Houghton, Fiona J., McMillan, Paul J., Hanssen, Eric and Gleeson, Paul A. (2018). The Golgi ribbon in mammalian cells negatively regulates autophagy by modulating mTOR activity. Journal of Cell Science, 131 (3), 1-15. doi: 10.1242/jcs.211987

Plakophilin3 increases desmosome assembly, size and stability by increasing expression of desmocollin2

Gurjar, Mansa, Raychaudhuri, Kumarkrishna, Mahadik, Snehal, Reddy, Divya, Atak, Apurva, Shetty, Trupti, Rao, Kruthi, Karkhanis, Mansi S., Gosavi, Prajakta, Sehgal, Lalit, Gupta, Sanjay and Dalal, Sorab N. (2018). Plakophilin3 increases desmosome assembly, size and stability by increasing expression of desmocollin2. Biochemical and Biophysical Research Communications, 495 (1), 768-774. doi: 10.1016/j.bbrc.2017.11.085

The Function of the Golgi Ribbon Structure – An Enduring Mystery Unfolds!

Gosavi, Prajakta and Gleeson, Paul A. (2017). The Function of the Golgi Ribbon Structure – An Enduring Mystery Unfolds!. BioEssays, 39 (11) 1700063, 1-9. doi: 10.1002/bies.201700063

The HOPS proteins hVps41 and hVps39 are required for homotypic and heterotypic late endosome fusion

Pols, Maaike S., ten Brink, Corlinda, Gosavi, Prajakta, Oorschot, Viola and Klumperman, Judith (2012). The HOPS proteins hVps41 and hVps39 are required for homotypic and heterotypic late endosome fusion. Traffic, 14 (2), 219-232. doi: 10.1111/tra.12027

Plakophilin3 loss leads to an increase in PRL3 levels promoting K8 dephosphorylation, which is required for transformation and metastasis

Khapare, Nileema, Kundu, Samrat T., Sehgal, Lalit, Sawant, Mugdha, Priya, Rashmi, Gosavi, Prajakta, Gupta, Neha, Alam, Hunain, Karkhanis, Madhura, Naik, Nishigandha, Vaidya, Milind M. and Dalal, Sorab N. (2012). Plakophilin3 loss leads to an increase in PRL3 levels promoting K8 dephosphorylation, which is required for transformation and metastasis. PLoS ONE, 7 (6) e38561. doi: 10.1371/journal.pone.0038561

E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly

Gosavi, Prajakta, Kundu, Samrat T., Khapare, Nileema, Sehgal, Lalit, Karkhanis, Mansi S. and Dalal, Sorab N. (2010). E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly. Cellular and Molecular Life Sciences, 68 (8), 1439-1454. doi: 10.1007/s00018-010-0531-3

Plakophilin3 downregulation leads to a decrease in cell adhesion and promotes metastasis

Kundu, Samrat T., Gosavi, Prajakta, Khapare, Nileema, Patel, Rachana, Hosing, Amol S., Maru, Girish B., Ingle, Arvind, DeCaprio, James A. and Dalal, Sorab N. (2008). Plakophilin3 downregulation leads to a decrease in cell adhesion and promotes metastasis. International Journal of Cancer, 123 (10), 2303-2314. doi: 10.1002/ijc.23797

Plakophilin3 expression results in an increase in the level of desmosomal components and the formation of calcium independent desmosomes

Gurjar, M. C., Raychaudhuri, K., Mahadik, S., Atak, A., Sehgal, L., Karkhanis, M., Gosavi, P. and Dalal, S. N. (2014). Plakophilin3 expression results in an increase in the level of desmosomal components and the formation of calcium independent desmosomes. FEBS EMBO 2014 Conference, Paris, France, 30 August - 4 September 2014. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.