The University of Queensland

Effects of Khat (Catha Edulis Forsk) on spatial learning and memory

Obonyo, Nchafatso G. and Patel, Nilesh B. (2011). Effects of Khat (Catha Edulis Forsk) on spatial learning and memory. Germany: LAP Lambert Academic Publishing.

Optimizing the patient and timing of the introduction of mechanical circulatory and extracorporeal respiratory support

Shekar, Kiran, Obonyo, Nchafatso and Fraser, John F. (2018). Optimizing the patient and timing of the introduction of mechanical circulatory and extracorporeal respiratory support. Mechanical circulatory and respiratory support. (pp. 441-468) edited by Shaun D. Gregory, Michael C. Stevens and John F. Fraser. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-810491-0.00014-X

Catalysing global surgery: a meta-research study on factors affecting surgical research collaborations with Africa

Kirengo, Thomas O., Dossajee, Hussein, Onyango, Evans M., Rachakonda, Reema H., Schneider, Bailey, Sela, Declan P., Hosseinzadeh, Zahra, Nadeem, Zohaib and Obonyo, Nchafatso G. (2024). Catalysing global surgery: a meta-research study on factors affecting surgical research collaborations with Africa. Systematic Reviews, 13 (1) 89. doi: 10.1186/s13643-024-02474-8

A novel speckle‐tracking echocardiography parameter assessing left ventricular afterload

Sato, Kei, Wildi, Karin, Chan, Jonathan, Palmieri, Chiara, Obonyo, Nchafatso G., Heinsar, Silver, Liu, Keibun, Livingstone, Samantha, Sato, Noriko, Ainola, Carmen, Abbate, Gabriella, Bouquet, Mahé, Wilson, Emily, Passmore, Margaret, Hyslop, Kieran, Platts, David G., Suen, Jacky, Bassi, Gianluigi Li and Fraser, John F. (2024). A novel speckle‐tracking echocardiography parameter assessing left ventricular afterload. European Journal of Clinical Investigation, 54 (2) e14106, 1-12. doi: 10.1111/eci.14106

Gastroenteritis Rehydration Of children with Severe Acute Malnutrition (GASTROSAM): A Phase II Randomised Controlled trial: Trial Protocol

Olupot-Olupot, Peter, Aloroker, Florence, Mpoya, Ayub, Mnjalla, Hellen, Paasi, George, Nakuya, Margaret, Houston, Kirsty, Obonyo, Nchafatso, Hamaluba, Mainga, Evans, Jennifer A, Dewez, Manuel, Atti, Salifou, Guindo, Ousmane, Ouattara, San Maurice, Chara, Abdullahi, Sainna, Hadiza Alhaji, Amos, Omokore Oluseyi, Ogundipe, Oluwakemi, Sunyoto, Temmy, Coldiron, Matthew, LANGENDORF, Celine, SCHERRER, Marie-Francoise, PETRUCCI, Roberta, Connon, Roisin, George, Elizabeth C., Gibb, Diana M. and Maitland, Kathryn (2024). Gastroenteritis Rehydration Of children with Severe Acute Malnutrition (GASTROSAM): A Phase II Randomised Controlled trial: Trial Protocol. Wellcome Open Research, 6, 160. doi: 10.12688/wellcomeopenres.16885.2

Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis

Obonyo, Nchafatso G., Sela, Declan P., Raman, Sainath, Rachakonda, Reema, Schneider, Bailey, Hoe, Louise E. See, Fanning, Jonathon P., Bassi, Gianluigi Li, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2023). Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis. Systematic Reviews, 12 (1) 221, 221. doi: 10.1186/s13643-023-02385-0

Cardiovascular Health Priorities in Sub-Saharan Africa

Obonyo, Nchafatso G. and Etyang, Anthony O. (2023). Cardiovascular Health Priorities in Sub-Saharan Africa. SN Comprehensive Clinical Medicine, 5 (1) 262. doi: 10.1007/s42399-023-01605-x

The effects of nitric oxide on coagulation and inflammation in ex‐vivo models of extracorporeal membrane oxygenation and cardiopulmonary bypass

Malfertheiner, Maximilian V., Ashlen, Garrett, Margaret, Passmore, Haymet, Andrew B., Richard, Webb I., von Bahr, Viktor, Millar, Jonathan E., Schneider, Bailey A., Obonyo, Nchafatso G., Debra, Black, Mahe, Bouquet, Nicole, Bartnikowski, Suen, Jacky Y. and Fraser, John F. (2023). The effects of nitric oxide on coagulation and inflammation in ex‐vivo models of extracorporeal membrane oxygenation and cardiopulmonary bypass. Artificial Organs, 47 (10), 1581-1591. doi: 10.1111/aor.14608

SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART)

Maitland, Kathryn, Hamaluba, Mainga, Obonyo, Nchafatso, Oguda, Emmanuel, Mogoka, Christabel, Williams, Thomas N., Chaponda, Mike, Miti, Sam, Kamavu, Luc Kambale, Connon, Roisin, Gibb, Diana M., Dondorp, Arjen, Day, Nick, White, Nick, Walker, A. Sarah, George, Elizabeth C. and Severe Malaria in African Children A Research and Trials (SMAART) consortium (2023). SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART). Wellcome Open Research, 8, 484. doi: 10.12688/wellcomeopenres.20111.1

Donor heart ischemic time can be extended to 8 hours using hypothermic machine perfusion in sheep

See Hoe, Louise E., Bassi, Gianluigi Li, Wildi, Karin, Passmore, Margaret R., Bouquet, Mahe, Sato, Kei, Heinsar, Silver, Ainola, Carmen, Bartnikowski, Nicole, Wilson, Emily S., Hyslop, Kieran, Skeggs, Kris, Obonyo, Nchafatso G., Shuker, Tristan, Bradbury, Lucy, Palmieri, Chiara, Pedersen, Sanne-Engkilde, McDonald, Charles, Colombo, Sebastiano M., Wells, Matthew A., Reid, Janice D., O'Neill, Hollier, Livingstone, Samantha, Abbate, Gabriella, Haymet, Andrew, Jung, Jae-Seung, Sato, Noriko, James, Lynnette, He, Ting ... Fraser, John F. (2023). Donor heart ischemic time can be extended to 8 hours using hypothermic machine perfusion in sheep. The Journal of Heart and Lung Transplantation, 42 (8), 1015-1029. doi: 10.1016/j.healun.2023.03.020

Effects of transfusing older red blood cells and platelets on obstetric patient outcomes: a retrospective cohort study

Obonyo, Nchafatso G., Lu, Lawrence Y., White, Nicole M., Sela, Declan P., Rachakonda, Reema H., Teo, Derek, Tunbridge, Matthew, Sim, Beatrice, See Hoe, Louise E., Fanning, Jonathon P., Tung, John‐Paul, McKnoulty, Matthew, Bassi, Gianluigi Li, Suen, Jacky Y. and Fraser, John F. (2023). Effects of transfusing older red blood cells and platelets on obstetric patient outcomes: a retrospective cohort study. International Journal of Gynecology and Obstetrics, 164 (1), 184-191. doi: 10.1002/ijgo.14997

Effects of Red Blood Cell Transfusion on Patients Undergoing Cardiac Surgery in Queensland—A Retrospective Cohort Study

Dhanapathy, V., Obonyo, N., White, N., Sela, D., Rachakonda, R., Tunbridge, M., Sim, B., Teo, D., Hoe, L. See, Fanning, J., Tung, J., Suen, J. and Fraser, J. (2023). Effects of Red Blood Cell Transfusion on Patients Undergoing Cardiac Surgery in Queensland—A Retrospective Cohort Study. Heart, Lung and Circulation, 32, S321. doi: 10.1016/j.hlc.2023.06.458

Assessment and diagnosis of right ventricular failure—retrospection and future directions

Ro, Sun Kyun, Sato, Kei, Ijuin, Shinichi, Sela, Declan, Fior, Gabriele, Heinsar, Silver, Kim, Ji Young, Chan, Jonathan, Nonaka, Hideaki, Lin, Aaron C. W., Bassi, Gianluigi Li, Platts, David G., Obonyo, Nchafatso G., Suen, Jacky Y. and Fraser, John F. (2023). Assessment and diagnosis of right ventricular failure—retrospection and future directions. Frontiers in Cardiovascular Medicine, 10 1030864, 1-17. doi: 10.3389/fcvm.2023.1030864

Interleukin-6 inhibitors in non-COVID-19 ARDS: analyzing the past to step into the post-COVID-19 era

Gandini, Lucia, Fior, Gabriele, Schibler, Andreas, Obonyo, Nchafatso G., Li Bassi, Gianluigi, Suen, Jacky Y. and Fraser, John F. (2023). Interleukin-6 inhibitors in non-COVID-19 ARDS: analyzing the past to step into the post-COVID-19 era. Critical Care, 27 (1) 124, 124. doi: 10.1186/s13054-023-04394-w

A novel speckle-tracking echocardiographic parameter considering left ventricular loading condition in cardiogenic shock during VA ECMO

Sato, Kei, Heinsar, Silver, Wildi, Karin Susanne, Obonyo, Nchafatso, LIU, KEIBUN, Farah, Samia, Ainola, Carmen, Sato, Noriko, Fior, Gabriele, Ro, Sun Kyun, Gandini, Lucia, Ijuin, Shinichi, Bouquet, Mahe, Wilson, Emily, Passmore, Margaret, Hyslop, Kieran, Chan, Jonathan H., Platts, David, Suen, Jacky, Bassi, Gianluigi Li and Fraser, John (2023). A novel speckle-tracking echocardiographic parameter considering left ventricular loading condition in cardiogenic shock during VA ECMO. Journal of the American College of Cardiology, 81 (8) 1396, 1-1. doi: 10.1016/s0735-1097(23)01840-5

Hemorrhage, disseminated intravascular coagulopathy, and thrombosis complications among critically ill patients with COVID-19: an international COVID-19 critical care consortium study

Fanning, Jonathon P., Weaver, Natasha, Fanning, Robert B., Griffee, Matthew J., Cho, Sung-Min, Panigada, Mauro, Obonyo, Nchafatso G., Zaaqoq, Akram M., Rando, Hannah, Chia, Yew Woon, Fan, Bingwen Eugene, Sela, Declan, Chiumello, Davide, Coppola, Silvia, Labib, Ahmed, Whitman, Glenn J. R., Arora, Rakesh C., Kim, Bo S., Motos, Anna, Torres, Antoni, Barbé, Ferran, Grasselli, Giacomo, Zanella, Alberto, Etchill, Eric, Usman, Asad Ali, Feth, Maximilian, White, Nicole M., Suen, Jacky Y., Li Bassi, Gianluigi ... on behalf of the COVID-19 Critical Care Consortium (2023). Hemorrhage, disseminated intravascular coagulopathy, and thrombosis complications among critically ill patients with COVID-19: an international COVID-19 critical care consortium study. Critical Care Medicine, 51 (5), 619-631. doi: 10.1097/ccm.0000000000005798

Resuscitation Associated Endotheliopathy (PubMed)

Obonyo, Nchafatso G., Sela, Declan P., Raman, Sainath, Rachakonda, Reema, Schneider, Bailey, Hoe, Louise E. See, Fanning, Jonathon P., Bassi, Gianluigi Li, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2023). Resuscitation Associated Endotheliopathy (PubMed). searchRxiv, 2023. doi: 10.1079/searchrxiv.2023.00206

A clinical and physiological prospective observational study on the management of pediatric shock in the post-fluid expansion as supportive therapy trial era

Obonyo, Nchafatso G., Olupot-Olupot, Peter, Mpoya, Ayub, Nteziyaremye, Julius, Chebet, Martin, Uyoga, Sophie, Muhindo, Rita, Fanning, Jonathon P., Shiino, Kenji, Chan, Jonathan, Fraser, John F. and Maitland, Kathryn (2022). A clinical and physiological prospective observational study on the management of pediatric shock in the post-fluid expansion as supportive therapy trial era. Pediatric Critical Care Medicine, Publish Ahead of Print (7), 502-513. doi: 10.1097/pcc.0000000000002968

Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis

Li Bassi, Gianluigi, Gibbons, Kristen, Suen, Jacky Y., Dalton, Heidi J., White, Nicole, Corley, Amanda, Shrapnel, Sally, Hinton, Samuel, Forsyth, Simon, Laffey, John G., Fan, Eddy, Fanning, Jonathon P., Panigada, Mauro, Bartlett, Robert, Brodie, Daniel, Burrell, Aidan, Chiumello, Davide, Elhazmi, Alyaa, Esperatti, Mariano, Grasselli, Giacomo, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Marwali, Eva, Merson, Laura, Murthy, Srinivas, Nichol, Alistair, Ogino, Mark, Pelosi, Paolo ... The COVID-19 Critical Care Consortium (2022). Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis. Critical Care, 26 (1) 141, 141. doi: 10.1186/s13054-022-03983-5

Venovenous extracorporeal membrane oxygenation in patients with acute covid-19 associated respiratory failure: comparative effectiveness study

Urner, Martin, Barnett, Adrian G., Bassi, Gianluigi Li, Brodie, Daniel, Dalton, Heidi J., Ferguson, Niall D., Heinsar, Silver, Hodgson, Carol L., Peek, Giles, Shekar, Kiran, Suen, Jacky Y., Fraser, John F., Fan, Eddy, COVID-19 Critical Care Consortium Investigators and Obonyo, Nchafatso (2022). Venovenous extracorporeal membrane oxygenation in patients with acute covid-19 associated respiratory failure: comparative effectiveness study. BMJ, 377 e068723, e068723. doi: 10.1136/bmj-2021-068723

Hypothermic ex vivo perfusion of donor hearts can safely preserve post-transplant cardiac function in sheep for 8 hours

See Hoe, Louise E., Bouquet, Mahe, Hyslop, Kieran, Passmore, Margaret R., Wells, Matthew A., Sato, Kei, Wilson, Emily, Wildi, Karin, Skeggs, Kris, Palmeri, Chiara, Reid, Janice, O'Neill, Hollier, Bartnikowski, Nicole, Jung, Jae-Seung, Ainola, Carmen, Abbate, Gabriella, Colombo, Sebastiano M., Obonyo, Nchafatso G., McDonald, Charles, Shuker, Tristan, Heinsar, Silver, Haymet, Andrew, Pedersen, Sanne, Molenaar, Peter, Li Bassi, Gianluigi, Suen, Jacky Y., McGiffin, David C. and Fraser, John F. (2022). Hypothermic ex vivo perfusion of donor hearts can safely preserve post-transplant cardiac function in sheep for 8 hours. The FASEB Journal, 36 (S1). doi: 10.1096/fasebj.2022.36.S1.R3270

Exploration of the utility of speckle-tracking echocardiography during mechanical ventilation and mechanical circulatory support

Sato, Kei, Chan, Jonathan, Appadurai, Vinesh, Obonyo, Nchafatso, See Hoe, Louise, Suen, Jacky Y. and Fraser, John F. (2022). Exploration of the utility of speckle-tracking echocardiography during mechanical ventilation and mechanical circulatory support. Critical Care Explorations, 4 (4) e0666, 1-10. doi: 10.1097/CCE.0000000000000666

Impact of renin-angiotensin-aldosterone system inhibition on mortality in critically ill COVID-19 patients with pre-existing hypertension: a prospective cohort study

Sato, Kei, White, Nicole, Fanning, Jonathon P., Obonyo, Nchafatso, Yamashita, Michael H., Appadurai, Vinesh, Ciullo, Anna, May, Meryta, Worku, Elliott T., Helms, Leticia, Ohshimo, Shinichiro, Juzar, Dafsah A., Suen, Jacky Y., Bassi, Gianluigi Li, Fraser, John F., Arora, Rakesh C. and on behalf of COVID-19 Critical Care Consortium Investigators (2022). Impact of renin-angiotensin-aldosterone system inhibition on mortality in critically ill COVID-19 patients with pre-existing hypertension: a prospective cohort study. BMC Cardiovascular Disorders, 22 (1) 123, 123. doi: 10.1186/s12872-022-02565-1

A clinically relevant sheep model of orthotopic heart transplantation 24 h after donor brainstem death

See Hoe, Louise E., Wildi, Karin, Obonyo, Nchafatso G., Bartnikowski, Nicole, McDonald, Charles, Sato, Kei, Heinsar, Silver, Engkilde-Pedersen, Sanne, Diab, Sara, Passmore, Margaret R., Wells, Matthew A., Boon, Ai-Ching, Esguerra, Arlanna, Platts, David G., James, Lynnette, Bouquet, Mahe, Hyslop, Kieran, Shuker, Tristan, Ainola, Carmen, Colombo, Sebastiano M., Wilson, Emily S., Millar, Jonathan E., Malfertheiner, Maximillian V., Reid, Janice D., O’Neill, Hollier, Livingstone, Samantha, Abbate, Gabriella, Sato, Noriko, He, Ting ... Fraser, John F. (2021). A clinically relevant sheep model of orthotopic heart transplantation 24 h after donor brainstem death. Intensive Care Medicine Experimental, 9 (1) 60, 1-24. doi: 10.1186/s40635-021-00425-4

Assessment of 28-day in-hospital mortality in mechanically ventilated patients with coronavirus disease 2019: an international cohort study

Li Bassi, Gianluigi, Suen, Jacky Y., White, Nicole, Dalton, Heidi J., Fanning, Jonathon, Corley, Amanda, Shrapnel, Sally, Hinton, Samuel, Forsyth, Simon, Parsons, Rex, Laffey, John G., Fan, Eddy, Bartlett, Robert, Brodie, Daniel, Burrell, Aidan, Chiumello, Davide, Elhazmi, Alyaa, Grasselli, Giacomo, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Marwali, Eva, Merson, Laura, Murthy, Srinivas, Nichol, Alistair, Panigada, Mauro, Pelosi, Paolo, Torres, Antoni, Ng, Pauline Yeung ... Obonyo, Nchafatso (2021). Assessment of 28-day in-hospital mortality in mechanically ventilated patients with coronavirus disease 2019: an international cohort study. Critical Care Explorations, 3 (11) e0567, e0567. doi: 10.1097/cce.0000000000000567

Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model

Walweel, K., Boon, A. C., See Hoe, L. E., Obonyo, N. G., Pedersen, S. E., Diab, S. D., Passmore, M. R., Hyslop, K., Colombo, S. M., Bartnikowski, N. J., Bouquet, M., Wells, M. A., Black, D. M., Pimenta, L. P., Stevenson, A. K., Bisht, K., Skeggs, K., Marshall, L., Prabhu, A., James, L. N., Platts, D. G., Macdonald, P. S., McGiffin, D. C., Suen, J. Y. and Fraser, J. F. (2021). Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model. Biomedical Journal, 45 (5), 776-787. doi: 10.1016/j.bj.2021.10.007

Characterizing preclinical sub-phenotypic models of acute respiratory distress syndrome: an experimental ovine study

Millar, Jonathan E., Wildi, Karin, Bartnikowski, Nicole, Bouquet, Mahe, Hyslop, Kieran, Passmore, Margaret R., Ki, Katrina K., See Hoe, Louise E., Obonyo, Nchafatso G., Neyton, Lucile, Pedersen, Sanne, Rozencwajg, Sacha, Baillie, J. Kenneth, Li Bassi, Gianluigi, Suen, Jacky Y., McAuley, Daniel F. and Fraser, John F. (2021). Characterizing preclinical sub-phenotypic models of acute respiratory distress syndrome: an experimental ovine study. Physiological Reports, 9 (19) e15048, e15048. doi: 10.14814/phy2.15048

Global infectious disease research collaborations in crises: building capacity and inclusivity through cooperation

Fanning, Jonathon P., Murthy, Srinivas, Obonyo, Nchafatso G., Baillie, J. Kenneth, Webb, Steve, Dalton, Heidi J. and Fraser, John F. (2021). Global infectious disease research collaborations in crises: building capacity and inclusivity through cooperation. Globalization and Health, 17 (1) 84, 1-6. doi: 10.1186/s12992-021-00731-2

Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death

Wells, Matthew A., See Hoe, Louise E., Molenaar, Peter, Pedersen, Sanne, Obonyo, Nchafatso G., McDonald, Charles I., Mo, Weilan, Bouquet, Mahè, Hyslop, Kieran, Passmore, Margaret R., Bartnikowski, Nicole, Suen, Jacky Y., Peart, Jason N., McGiffin, David C., Fraser, John F. and on behalf of the Dead Heart Project (2021). Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death. Pharmacological Research, 169 105631, 1-12. doi: 10.1016/j.phrs.2021.105631

An appraisal of respiratory system compliance in mechanically ventilated covid-19 patients

Li Bassi, Gianluigi, Suen, Jacky Y, Dalton, Heidi J, White, Nicole, Shrapnel, Sally, Fanning, Jonathon P, Liquet, Benoit, Hinton, Samuel, Vuorinen, Aapeli, Booth, Gareth, Millar, Jonathan E, Forsyth, Simon, Panigada, Mauro, Laffey, John, Brodie, Daniel, Fan, Eddy, Torres, Antoni, Chiumello, Davide, Corley, Amanda, Elhazmi, Alyaa, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Murthy, Srinivas, Nichol, Alistair, Ng, Pauline Yeung, Ogino, Mark, Pesenti, Antonio, Trieu, Huynh Trung ... Obonyo, Gikenyi N. (2021). An appraisal of respiratory system compliance in mechanically ventilated covid-19 patients. Critical Care, 25 (1) 199, 1-22. doi: 10.1186/s13054-021-03518-4

Donor heart preservation by hypothermic ex vivo perfusion - improved recipient survival and successful prolongation of ischemic time

Hoe, L.E. See, Wildi, K., Skeggs, K., Bouquet, M., Sato, K., Jung, J., Ainola, C., Hyslop, K., Heinsar, S., Abbate, G., Colombo, S.M., Passmore, M., Wood, E.S., Wells, M., Bartnikowski, N., O'Neill, H., Reid, J., Shuker, T., Haymet, A., Livingstone, S., Sato, N., Obonyo, N., James, L., He, T., McDonald, C., Mullins, D., Engkilde-Pedersen, S., Diab, S., Millar, J.E. ... Fraser, J.F. (2021). Donor heart preservation by hypothermic ex vivo perfusion - improved recipient survival and successful prolongation of ischemic time. The Journal of Heart and Lung Transplantation, 40 (4), S51-S51. doi: 10.1016/j.healun.2021.01.1864

Gastroenteritis Rehydration Of children with Severe Acute Malnutrition (GASTROSAM): a phase II randomised controlled trial: trial protocol

Maitland, Kathryn, Olupot-Olupot, Peter, Aloroker, Florence, Mpoya, Ayub, Mnjalla, Hellen, Passi, George, Nakuya, Margaret, Houston, Kirsty, Obonyo, Nchafatso, Hamaluba, Mainga, Evans, Jennifer A, Connon, Roisin, George, Elizabeth C and Gibb, Diana M (2021). Gastroenteritis Rehydration Of children with Severe Acute Malnutrition (GASTROSAM): a phase II randomised controlled trial: trial protocol. Wellcome Open Research, 6 160, 160. doi: 10.12688/wellcomeopenres.16885.1

Characterising pre-clinical sub-phenotypic models of Acute Respiratory Distress Syndrome: an experimental ovine study

Millar, Jonathan E., Wildi, Karin, Bartnikowski, Nicole, Bouquet, Mahe, Hyslop, Kieran, Passmore, Margaret R., Ki, Katrina K., See Hoe, Louise E., Obonyo, Nchafatso G., Neyton, Lucile, Pedersen, Sanne, Rozencwajg, Sacha, Baillie, J. Kenneth, Li Bassi, Gianluigi, Suen, Jacky Y, McAuley, Daniel F. and Fraser, John F. (2020). Characterising pre-clinical sub-phenotypic models of Acute Respiratory Distress Syndrome: an experimental ovine study.

Microvascular dysfunction in septic and dengue shock: pathophysiology and implications for clinical management

McBride, Angela, Chanh, Ho Q., Fraser, John F., Yacoub, Sophie and Obonyo, Nchafatso G. (2020). Microvascular dysfunction in septic and dengue shock: pathophysiology and implications for clinical management. Global Cardiology Science and Practice, 2020 (2) e202029, e202029. doi: 10.21542/gcsp.2020.29

Heart transplantation from brain dead donors: a systematic review of animal models

See Hoe, Louise E., Wells, Matthew A., Bartnikowski, Nicole, Obonyo, Nchafatso G., Millar, Jonathan E., Khoo, Aimee, Ki, Katrina K., Shuker, Tristan, Ferraioli, Alessandro, Colombo, Sebastiano M., Chan, Wandy, McGiffin, David C., Suen, Jacky Y. and Fraser, John F. (2020). Heart transplantation from brain dead donors: a systematic review of animal models. Transplantation, 104 (11), 2272-2289. doi: 10.1097/tp.0000000000003217

Endothelin receptor antagonist improves donor lung function in an ex vivo perfusion system

Walweel, K., Skeggs, K., Boon, A. C., See Hoe, L. E., Bouquet, M., Obonyo, N. G., Pedersen, S. E., Diab, S. D., Passmore, M. R., Hyslop, K., Wood, E. S., Reid, J., Colombo, S. M., Bartnikowski, N. J., Wells, M. A., Black, D., Pimenta, L. P., Stevenson, A. K., Bisht, K., Marshall, L., Prabhu, D. A., James, L., Platts, D. G., MacDonald, P. S., McGiffin, D. C., Suen, J. Y. and Fraser, J. F. (2020). Endothelin receptor antagonist improves donor lung function in an ex vivo perfusion system. Journal of Biomedical Science, 27 (1) 96, 96. doi: 10.1186/s12929-020-00690-7

Combined mesenchymal stromal cell therapy and ECMO in ARDS: a controlled experimental study in sheep

Millar, Jonathan E., Bartnikowski, Nicole, Passmore, Margaret R., Obonyo, Nchafatso G, Malfertheiner, Maximillian V., von Bahr, Viktor, Redd, Meredith A., See Hoe, Louise, Ki, Katrina K., Pedersen, Sanne, Boyle, Andrew J., Baillie, J Kenneth, Shekar, Kiran, Palpant, Nathan, Suen, Jacky Y., Matthay, Michael A., McAuley, Daniel F., Fraser, John F. and Combining Extracorporeal Life Support and Cell Therapy in Critical Illness (CELTIC) investigators (2020). Combined mesenchymal stromal cell therapy and ECMO in ARDS: a controlled experimental study in sheep. American Journal of Respiratory and Critical Care Medicine, 202 (3) rccm.201911-2143OC, 383-392. doi: 10.1164/rccm.201911-2143oc

Corrigendum: Sepsis: changing definitions, unchanging treatment (vol 6, 425, 2019)

Obonyo, Nchafatso Gikenyi, Schlapbach, Luregn Jan and Fraser, John Francis (2020). Corrigendum: Sepsis: changing definitions, unchanging treatment (vol 6, 425, 2019). Frontiers in Pediatrics, 7 538, 538. doi: 10.3389/fped.2019.00538

Gastroenteritis aggressive versus slow treatment for rehydration (GASTRO): a phase II rehydration trial for severe dehydration: WHO plan C versus slow rehydration

Houston, Kirsty A., Gibb, Jack, Olupot-Olupot, Peter, Obonyo, Nchafatso, Mpoya, Ayub, Nakuya, Margaret, Muhindo, Rita, Uyoga, Sophie, Evans, Jennifer A., Connon, Roisin, Gibb, Diana M., George, Elizabeth C. and Maitland, Kathryn (2019). Gastroenteritis aggressive versus slow treatment for rehydration (GASTRO): a phase II rehydration trial for severe dehydration: WHO plan C versus slow rehydration. BMC Medicine, 17 (1) 122. doi: 10.1186/s12916-019-1356-z

Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock

Passmore, Margaret R., Obonyo, Nchafatso G., Byrne, Liam, Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Fung, Yoke L., Spanevello, Michelle M., Fauzi, Mohd H., Pedersen, Sanne E., Simonova, Gabriela, Anstey, Chris M., Shekar, Kiran, Tung, John-Paul, Maitland, Kathryn and Fraser, John F. (2019). Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock. Thrombosis Research, 176, 39-45. doi: 10.1016/j.thromres.2019.02.015

Extracorporeal membrane oxygenation (ECMO) and the acute respiratory distress syndrome (ARDS): a systematic review of pre-clinical models

Millar, Jonathan E., Bartnikowski, Nicole, von Bahr, Viktor, Malfertheiner, Maximilian V., Obonyo, Nchafatso G., Belliato, Mirko, Suen, Jacky Y., Combes, Alain, McAuley, Daniel F., Lorusso, Roberto and Fraser, John F. (2019). Extracorporeal membrane oxygenation (ECMO) and the acute respiratory distress syndrome (ARDS): a systematic review of pre-clinical models. Intensive Care Medicine Experimental, 7 (1) 18, 18. doi: 10.1186/s40635-019-0232-7

Assessment of myocardial function in Kenyan children with severe, acute malnutrition the Cardiac Physiology in Malnutrition (CAPMAL) Study

Brent, Bernadette, Obonyo, Nchafatso, Akech, Samuel, Shebbe, Mohammed, Mpoya, Ayub, Mturi, Neema, Berkley, James A., Tulloh, Robert M. R. and Maitland, Kathryn (2019). Assessment of myocardial function in Kenyan children with severe, acute malnutrition the Cardiac Physiology in Malnutrition (CAPMAL) Study. JAMA Network Open, 2 (3). doi: 10.1001/jamanetworkopen.2019.1054

Neuron specific enolase and matrix metalloproteinase 9 signal perioperative silent brain infarction during or after transcatheter aortic valve implantation

Fanning, Jonathon P., Hoe, Louise E. See, Passmore, Margaret R., Barnett, Adrian G., Obonyo, Nchafatso G., Millar, Jonathan E., Wesley, Allan J., Suen, Jacky Y. and Fraser, John F. (2019). Neuron specific enolase and matrix metalloproteinase 9 signal perioperative silent brain infarction during or after transcatheter aortic valve implantation. The American Journal of Cardiology, 123 (3), 434-439. doi: 10.1016/j.amjcard.2018.10.022

Sepsis: changing definitions, unchanging treatment

Obonyo, Nchafatso Gikenyi, Schlapbach, Luregn Jan and Fraser, John Francis (2019). Sepsis: changing definitions, unchanging treatment. Frontiers in Pediatrics, 6 (JAN) 425, 425. doi: 10.3389/fped.2018.00425

Pre-clinical study protocol: Blood transfusion in endotoxaemic shock

Obonyo, Nchafatso G., Byrne, Liam, Tung, John-Paul, Simonova, Gabriela, Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Mohd H., Pimenta, Leticia P., Millar, Jonathan E., Fanning, Jonathon P., Van Haren, Frank, Anstey, Chris M., Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2019). Pre-clinical study protocol: Blood transfusion in endotoxaemic shock. MethodsX, 6, 1124-1132. doi: 10.1016/j.mex.2019.05.005

Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock

Passmore, Margaret R., Byrne, Liam, Obonyo, Nchafatso G., See Hoe, Louise E., Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Bisht, Kavita, Tung, John-Paul, Fauzi, Mohd H., Narula, Monica, Pedersen, Sanne E., Esguerra-Lallen, Arlanna, Simonova, Gabriela, Sultana, Annette, Anstey, Chris M., Shekar, Kiran, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2018). Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock. Respiratory Research, 19 (1) 231, 231. doi: 10.1186/s12931-018-0935-4

Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia

Byrne, Liam, Obonyo, Nchafatso G., Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Pedersen, Sanne, Hashairi Fauzi, Mohd, Pretti Pimenta, Leticia, Van Haren, Frank, Anstey, Christopher M., Cullen, Louise, Tung, John-Paul, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia. American Journal of Respiratory and Critical Care Medicine, 198 (8), 1043-1054. doi: 10.1164/rccm.201801-0064OC

An ovine model of hyperdynamic endotoxemia and vital organ metabolism

Byrne, Liam, Obonyo, Nchafatso G., Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai Ching, Hoe, Louise See, Hay, Karen, Van Haren, Frank, Tung, John-Paul, Cullen, Louise, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). An ovine model of hyperdynamic endotoxemia and vital organ metabolism. Shock, 49 (1), 99-107. doi: 10.1097/SHK.0000000000000904

Acquired von willebrand syndrome in respiratory extracorporeal life support: A systematic review of the literature

Malfertheiner, M. V., Pimenta, L. P., Von Bahr, V., Millar, J. E., Obonyo, N. G., Suen, J. Y., Pellegrino, V. and Fraser, J. F. (2017). Acquired von willebrand syndrome in respiratory extracorporeal life support: A systematic review of the literature. Critical Care and Resuscitation, 19, 45-52.

Gastroenteritis Aggressive Versus Slow Treatment For Rehydration (GASTRO). A pilot rehydration study for severe dehydration: WHO plan C versus slower rehydration

Houston, Kirsty A., Gibb, Jack G., Mpoya, Ayub, Obonyo, Nchafatso, Olupot-Olupot, Peter, Nakuya, Margeret, Evans, Jennifer A., George, Elizabeth C., Gibb, Diana M. and Maitland, Kathryn (2017). Gastroenteritis Aggressive Versus Slow Treatment For Rehydration (GASTRO). A pilot rehydration study for severe dehydration: WHO plan C versus slower rehydration. Wellcome Open Research, 2 62, 62. doi: 10.12688/wellcomeopenres.12261.1

Left Ventricular Global Strain Analysis by Two-Dimensional Speckle-Tracking Echocardiography: The Learning Curve

Chan, Jonathan, Shiino, Kenji, Obonyo, Nchafatso G., Hanna, Joseph, Chamberlain, Robert, Small, Andrew, Scalia, Isabel G., Scalia, William, Yamada, Akira, Hamilton-Craig, Christian R., Scalia, Gregory M. and Zamorano, Jose Luis (2017). Left Ventricular Global Strain Analysis by Two-Dimensional Speckle-Tracking Echocardiography: The Learning Curve. Journal of the American Society of Echocardiography, 30 (11), 1081-1090. doi: 10.1016/j.echo.2017.06.010

Myocardial and haemodynamic responses to two fluid regimens in African children with severe malnutrition and hypovolaemic shock (AFRIM study)

Obonyo, Nchafatso, Brent, Bernadette, Olupot-Olupot, Peter, van Hensbroek, Michael Boele, Kuipers, Irene, Wong, Sidney, Shiino, Kenji, Chan, Jonathan, Fraser, John, van Woensel, Job B. M. and Maitland, Kathryn (2017). Myocardial and haemodynamic responses to two fluid regimens in African children with severe malnutrition and hypovolaemic shock (AFRIM study). Critical Care, 21. doi: 10.1186/s13054-017-1679-0

Effects of volume resuscitation on the microcirculation in animal models of lipopolysaccharide sepsis: a systematic review

Obonyo, Nchafatso G., Fanning, Jonathon P., Ng, Angela S. Y., Pimenta, Leticia P., Shekar, Kiran, Platts, David G., Maitland, Kathryn and Fraser, John F. (2016). Effects of volume resuscitation on the microcirculation in animal models of lipopolysaccharide sepsis: a systematic review. Intensive Care Medicine Experimental, 4 (1) 38, 1-16. doi: 10.1186/s40635-016-0112-3

Career preferences of final year medical students at a medical school in Kenya-a cross sectional study

Dossajee, Hussein, Obonyo, Nchafatso and Ahmed, Syed Masud (2016). Career preferences of final year medical students at a medical school in Kenya-a cross sectional study. BMC Medical Education, 16 (1) 5. doi: 10.1186/s12909-016-0528-1

Fluid management of shock in severe malnutrition: what is the evidence for current guidelines and what lessons have been learned from clinical studies and trials in other pediatric populations?

Obonyo, Nchafatso and Maitland, Kathryn (2014). Fluid management of shock in severe malnutrition: what is the evidence for current guidelines and what lessons have been learned from clinical studies and trials in other pediatric populations?. Food and Nutrition Bulletin, 35 (2), S71-S78. doi: 10.1177/15648265140352S111

Tailoring management of severe and complicated malnutrition: more research is required first

Brent, Bernadette, Obonyo, Nchafatso and Maitland, Kathryn (2012). Tailoring management of severe and complicated malnutrition: more research is required first. Pathogens and Global Health, 106 (4), 197-199. doi: 10.1179/2047772412Z.00000000061

Spinal tuberculosis among human immunodeficiency virus-negative patients in a Kenyan tertiary hospital: a 5-year synopsis

Mwachaka, Philip M., Ranketi, Simeon S., Nchafatso, Obonyo G., Kasyoka, Ben M. and Kiboi, Julius G. (2011). Spinal tuberculosis among human immunodeficiency virus-negative patients in a Kenyan tertiary hospital: a 5-year synopsis. The Spine Journal, 11 (4), 265-269. doi: 10.1016/j.spinee.2011.01.033

Ventriculoperitoneal shunt complications: a three-year retrospective study in a Kenyan National Teaching and Referral Hospital

Mwachaka, Philip M., Obonyo, Nchafatso G., Mutiso, Ben K., Ranketi, Simeon and Mwang'ombe, Nimrod (2010). Ventriculoperitoneal shunt complications: a three-year retrospective study in a Kenyan National Teaching and Referral Hospital. Pediatric Neurosurgery, 46 (1), 1-5. doi: 10.1159/000314050

Management pathway for congenital heart disease at Kenyatta National Hospital, Nairobi

Awori, M. N., Ogendo, S. W. O., Gitome, S. W., Ong'uti, S. K. and Obonyo, N. G. (2007). Management pathway for congenital heart disease at Kenyatta National Hospital, Nairobi. The East African Medical Journal, 84 (7), 312-317. doi: 10.4314/eamj.v84i7.9585

A novel speckle-tracking echocardiographic parameter assessing left ventricular loading during VA ECMO in a pre-clinical model of cardiogenic shock

Sato, K., Heinsar, S., Obonyo, N., Wildi, K., Liu, K., Farah, S., Ainola, C., Sato, N., Ijuin, S., Ro, S. Kyun, Fior, G., Gandini, L., Bouquet, M., Wilson, E., Passmore, M., Hyslop, K., Chan, J., Platts, D., Scalia, G., Suen, J., Bassi, G. Li and Fraser, J. (2023). A novel speckle-tracking echocardiographic parameter assessing left ventricular loading during VA ECMO in a pre-clinical model of cardiogenic shock. 71st Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Adelaide, SA Australia, 3-6 August 2023. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2023.06.562

A novel speckle-tracking echocardiographic parameter considering left ventricular loading condition in cardiogenic shock during VA ECMO

Sato, Kei, Heinsar, Silver, Wildi, Karin Susanne, Obonyo, Nchafatso, Liu, Keibun, Farah, Samia, Ainola, Carmen, Sato, Noriko, Fior, Gabriele, Ro, Sun Kyun, Gandini, Lucia, Ijuin, Shinichi, Bouquet, Mahe, Wilson, Emily, Passmore, Margaret, Hyslop, Kieran, Chan, Jonathan H., Platts, David, Suen, Jacky, Li Bassi, Gianluigi and Fraser, John (2023). A novel speckle-tracking echocardiographic parameter considering left ventricular loading condition in cardiogenic shock during VA ECMO. 72nd Annual Scientific Session (ACC), New Orleans, LA, United States, 4-6 March 2023. San Diego, CA, United States: Elsevier.

Post-transplant cardiac contractility and mitochondrial function is preserved following 8 hours hypothermic ex vivo perfusion in sheep

See Hoe, L., Bouquet, M., Hyslop, K., Passmore, M., Wells, M., Sato, K., Wilson, E., Wildi, K., Skeggs, K., Palmeri, C., Reid, J., O'Neill, H., Bartnikowski, N., Jung, J., Ainola, C., Abbate, G., Colombo, S., Obonyo, N., McDonald, C., Shuker, T., Heinsar, S., Haymet, A., Engkilde-Pedersen, S., Peart, J., Molenaar, P., Li Bassi, G., Suen, J., McGiffin, D. and Fraser, J. (2022). Post-transplant cardiac contractility and mitochondrial function is preserved following 8 hours hypothermic ex vivo perfusion in sheep. 70th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Gold Coast, QLD, Australia, 11-14 August 2022. Chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2022.06.547

Donor heart preservation by hypothermic ex vivo perfusion - improved recipient survival and successful prolongation of ischemic time

Hoe, L. E. See, Wildi, K., Skeggs, K., Bouquet, M., Sato, K., Jung, J., Ainola, C., Hyslop, K., Heinsar, S., Abbate, G., Colombo, S. M., Passmore, M., Wood, E. S., Wells, M., Bartnikowski, N., O'Neill, H., Reid, J., Shuker, T., Haymet, A., Livingstone, S., Sato, N., Obonyo, N., James, L., He, T., McDonald, C., Mullins, D., Engkilde-Pedersen, S., Diab, S., Millar, J. E. ... Fraser, J. F. (2021). Donor heart preservation by hypothermic ex vivo perfusion - improved recipient survival and successful prolongation of ischemic time. Philadelphia, PA, United States: Elsevier.

(-)-Noradrenaline sensitivity, contractility and mitochondrial function in an ovine model of brain stem death and transplantation

Wells, Matthew, Molenaar, Peter, Hoe, Louise See, Obonyo, Nchafatso, James, Lynette, Bouquet, Mahe, Bartnikowski, Nicole, Passmore, Margaret, Boone, Connie, Wilde, Karin, Weilan, Mo, Hyslop, Kieran, McDonald, Charles, Pedersen, Sanne, Suen, Jacky, Peart, Jason, McGiffin, David and Fraser, John (2020). (-)-Noradrenaline sensitivity, contractility and mitochondrial function in an ovine model of brain stem death and transplantation. 2019 ISHR World Congress, Beijing, China, 3-6 June 2019. London, United Kingdom: Academic Press. doi: 10.1016/j.yjmcc.2019.11.114

Donor brain stem death and cardiac transplantation causes mitochondrial dyscoupling and oxidative stress

Wells, Matthew, Seehoe, Louise, Zechovic, Olivia, Nchafatso, Obonyo, Bouquet, Mahe, Hyslop, Keiran, Black, Deborah, McDonald, Charles, Pedersen, Sanne, Suen, Jacky, Peart, Jason, McGiffin, David, Fraser, John and Lye, India (2020). Donor brain stem death and cardiac transplantation causes mitochondrial dyscoupling and oxidative stress. World Congress of Intensive Care, Melbourne, VIC Australia, 14-18 October 2019. Philadelphia, PA USA: Elsevier. doi: 10.1016/j.aucc.2020.04.098

Hypothermic ex vivo perfusion of brain dead donor hearts improves survival, systemic inflammation and cardiac function following heart transplantation

See Hoe, L., McGiffin, D., Wildi, K., Obonyo, N., Bouquet, M., Wells, M., Skeggs, K., McDonald, C., Engkilde-Pedersen, S., Bartnikowski, N., Colombo, S., Ainola, C., Passmore, M., Hyslop, K., Wood, E., Shuker, T., Sato, K., Jung, J., Heinser, S., James, L., Reid, J., O'Neill, H., Livingstone, S., Abbate, G., He, P., Sato, N., Boon, C., Black, D., Haymet, A. ... Fraser, J. (2020). Hypothermic ex vivo perfusion of brain dead donor hearts improves survival, systemic inflammation and cardiac function following heart transplantation. 8th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 14th Annual Australia and New Zealand Endovascular Therapies Meeting, Online, 11-13 December 2020. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2020.09.127

Hypothermic ex vivo perfusion preserves post-transplant donor cardiac function

Sato, K., See Hoe, L., Obonyo, N., Wildi, K., Colombo, S., Bouquet, M., Passmore, M., Bartnikowski, N., Wells, M., Skeggs, K., McDonald, C., Hyslop, K., Wood, E., Heinser, S., Ainola, C., Jung, J., James, L., Abbate, G., Haymet, A., Engkilde-Pedersen, S., Reid, J., O'Neill, H., Shuker, T., He, P., Sato, N., Diab, S., Mullins, D., Livingstone, S., Wang, X. ... Fraser, J. (2020). Hypothermic ex vivo perfusion preserves post-transplant donor cardiac function. 8th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 14th Annual Australia and New Zealand Endovascular Therapies Meeting, Virtual, 11-13 December 2020. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2020.09.128

Metabolic and mitochondrial alterations following brain death and heart transplantation

Hoe, L. E. See, Wells, M. A., Bouquet, M., Hyslop, K., Passmore, M. R., Bartnikowski, N., Obonyo, N. G., Reid, J., O'Neill, H., Shuker, T., McDonald, C., Engkilde-Pedersen, S., Wildi, K., Ainola, C., Skeggs, K., Jung, J., Colombo, S., Sato, K., James, L., He, P., Wood, E. S., Heinser, S., Wang, X., Abbate, G., Livingstone, S., Haymet, A., Walweel, K., Mullins, D., Marasco, S. ... Fraser, J. F. (2020). Metabolic and mitochondrial alterations following brain death and heart transplantation. 40th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT), Montreal, Canada, 22-25 April 2020. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.healun.2020.01.419

Characterisation of cardiac neurohormonal and inflammatory changes induced by brain death in a novel ovine heart transplant model

Hoe, L. See, Shuker, T., Bartnikowski, N., Passmore, M., Bouquet, M., Obonyo, N., Engkilde-Pedersen, S., McDonald, C., Wells, M., Boon, A., Hyslop, K., James, L., Wildi, K., Cullen, L., Bassi, G. Li, Suen, J., McGiffin, D. and Fraser, J. (2019). Characterisation of cardiac neurohormonal and inflammatory changes induced by brain death in a novel ovine heart transplant model. 67th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 13th Annual Australia and New Zealand Endovascular Therapies Meeting, Adelaide, Australia, 8-11 August 2019. chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2019.06.074

Packed Red Cell Age Associated With Adverse Cardiovascular Changes in an Ovine Model of Septic Shock Resuscitation

Fanning, Jonathon P., Obonyo, Nchafatso G., Tung, John-Paul, Byrne, Liam, Simonova, Gabriela, Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Hashairi Fauzi, Mohd, Pretti Pimenta, Leticia, Millar, Jonathan, Anstey, Christopher, van Haren, Frank, Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John (2018). Packed Red Cell Age Associated With Adverse Cardiovascular Changes in an Ovine Model of Septic Shock Resuscitation. American Heart Association's 2018 Scientific Sessions, Chicago, IL United States, 10-12 November 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1161/circ.138.suppl_1.17116

Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxemic shock

Obonyo, N., Byrne, L., Shiino, K., Diab, S., Dunster, K., Passmore, M., Boon, A.C., See Hoe, L., Pedersen, S., Fauzi, M., Pimenta, L., Van Haren, F., Shekar, K., Anstey, C., Tung, J.P., Cullen, L., Platts, D., Chan, J., Maitland, K. and Fraser, J. (2018). Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxemic shock. 9th Congress of the World Federation of Pediatric Intensive & Critical Care Societies (WFPICCS 2018), Singapore, 9-13 June 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0000538016.15507.8c

G265(P) Gastroenteritis aggressive versus slow treatment for rehydration (gastro study): a descriptive analysis

Houston, K., Gibb, J., Mpoya, A., Obonyo, N., Olupot-Olupot, P., George, E., Gibb, D. and Maitland, K. (2018). G265(P) Gastroenteritis aggressive versus slow treatment for rehydration (gastro study): a descriptive analysis. Annual Conference of Royal College of Paediatrics and Child Health, Glasgow, United Kingdom, 13-15 March 2018. London, United Kingdom: BMJ Publishing Group. doi: 10.1136/archdischild-2018-rcpch.258

Development of an ovine model of dilated cardiomyopathy to facilitate clinically translational research

Bartnikowski, N., Obonyo, N., Pedersen, S., Wells, M., Millar, J., Raffel, O., Suen, J., Gregory, S., Haqqani, H. and Fraser, J. (2018). Development of an ovine model of dilated cardiomyopathy to facilitate clinically translational research. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, QLD Australia, 2 - 5 August 2018. Chatswood, NSW Australia: Elsevier . doi: 10.1016/j.hlc.2018.06.110

Development of an ovine model of heart transplantation following 24-hour brain stem death

See Hoe, L., Engkilde-Pedersen, S., Obonyo, N., Wells, M., Boon, C., Bartnikowski, N., Passmore, M., McDonald, C., Black, D., Molenaar, P., Diab, S., Suen, J., Marasco, S., McGiffin, D. and Fraser, J. (2018). Development of an ovine model of heart transplantation following 24-hour brain stem death. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, Australia, 2-5 August 2018. Chatswood, NSW, Australia: Elsevier . doi: 10.1016/j.hlc.2018.06.111

Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxaemic shock

See Hoe, L., Obonyo, N., Byrne, L., Shiino, K., Diab, S., Dunster, K., Passmore, M., Boon, C., Engkilde-Pedersen, S., Esguerra, A., Fauzi, M., Pretti Pimenta, L., Simonova, G., Van Haren, F., Shekar, K., Anstey, C., Tung, J., Cullen, L., Platts, D., Chan, J., Maitland, K. and Fraser, J. (2018). Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxaemic shock. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, Australia, 2-5 August 2018. Chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2018.06.129

Inflammatory cytokine profiles in 24-hour brain stem death model

Boon, A. C., Hoe, L. E. See, Pederson, S. E., Obonyo, N. G., Wells, M. A., Bartnikowski, N. J., Passmore, M. R., Marshall, L., James, L., Tung, J., Suen, J. Y., Macdonald, P. S., McGiffin, D. C. and Fraser, J. F. (2018). Inflammatory cytokine profiles in 24-hour brain stem death model. 38th Annual Meeting and Scientific Sessions of the International-Society-for-Heart-and-Lung-Transplantation (ISHLT), Nice, France, 11-14 April 2018. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.healun.2018.01.506

Neuron specific enolase and matrix metaloproteinase 9 signal silent brain infarction associated with TAVI

Fanning, Jonathon P., Hoe, See Louise E., Passmore, Margaret R., Barnett, Adrian G., Obonyo, Nchafatso G., Millar, Jonathan E., Suen, Jacky Y. and Fraser, John F. (2018). Neuron specific enolase and matrix metaloproteinase 9 signal silent brain infarction associated with TAVI. Philadelphia, PA, United States: Lippincott Williams & Wilkins.

Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation

Fanning, Jonathon P., Obonyo, Nchafatso G., Tung, John-Paul, Byrne, Liam, Simonova, Gabriela, Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai-Ching, Hoe, See Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Hashairi Mohd, Pretti, Pimenta Leticia, Millar, Jonathan, Anstey, Christopher, van Haren, Frank, Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John (2018). Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation. -, -, 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins.

Pre-transplant microcirculatory profile in an ovine model of brain stem death

Tsui, Michelle, Obonyo, Nchafatso G., Boon, Ai Ching, Hoe, Louise See, Bartnikowski, Nicole J., Passmore, Margaret R., Pedersen, Sanne Engkilde S. P., Diab, Sara D., McGiffin, David C. and Fraser, John F. (2018). Pre-transplant microcirculatory profile in an ovine model of brain stem death. Owen Wangensteen Scientific Forum / Annual Clinical Congress of the American-College-of-Surgeons (ACS), Boston, MA, United States, 21-25 October 2018. New York, United States: Elsevier. doi: 10.1016/j.jamcollsurg.2018.08.608

Point-of-care testing in an ovine model of transfusion-related acute lung injury (TRALI)

Tung, John-Paul, Simonova, Gabriela, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Sultana, Annette, Hewlett, Elise, Obonyo, Nchafatso, Millar, Jonathan, Flower, Robert and Fraser, John (2017). Point-of-care testing in an ovine model of transfusion-related acute lung injury (TRALI). Pathology Update 2017, Sydney, NSW Australia, 24-26 February 2017. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.pathol.2016.12.309

Heart failure pre-clinical model development: echocardiography and cardiac strain evaluation

Obonyo, N., Bartnikowski, N., Haqqani, H., Pedersen, S., Millar, J., He, C., Shiino, K., Chan, J., Platts, D., Raffel, O., Gregory, S. and Fraser, J. (2017). Heart failure pre-clinical model development: echocardiography and cardiac strain evaluation. 65th Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting, Perth, WA Australia, 10-13 August 2017. Chatswood, NSW Australia: Elsevier Australia. doi: 10.1016/j.hlc.2017.06.212

Myocardial and microvascular physiology in septic shock and response to volume expansion treatment

Obonyo, Nchafatso Gikenyi (2021). Myocardial and microvascular physiology in septic shock and response to volume expansion treatment. PhD Thesis, Life, Health and Chemical Sciences; Faculty of Science Technology, Engineering and Mathematics, The Open University of London, United Kingdom. doi: 10.21954/ou.ro.00011dde