I am a Research Fellow in Bioinformatics, holding a joint position with QBI the Bredy group (50%) and IMB the Palpant group (50%). With over 15 years of experience in the bioinformatics/NGS field, my journey began with the greenfield development of three NGS platforms: 454, Illumina, and SOLiD. This experience has equipped me with extensive expertise in bioinformatic analysis, particularly in analyzing a variety of NGS data types. As the leader of the bioinformatics core facility at QBI from 2012 to 2022, my role was primarily focused on providing bioinformatics services. However, I have also been actively engaged in custom programming and analysis for numerous projects, allowing me to make significant intellectual contributions and deepen my involvement in research studies. Despite the typical service-oriented position of bioinformaticians, my publication record is notable, featuring over 40 peer-reviewed publications, with me serving as the first, co-first, or last author on 16 of them. Since 2019, my work has garnered 1,525 citations (as per Google Scholar, as of 12 Jan 2024), with 41.2% of my publications ranking in the top 10% of journals based on the CiteScore Percentile Source from SciVal. My contributions to bioinformatics are showcased in prestigious journals, with notable examples including lncRNA capture sequencing and ATAC-seq data analysis (Nature Communications, 2023) and (Cell Reports, 2022), de novo transcriptome assembly (Development, 2022), noncanonical structure Z-DNA analysis (Nature Neuroscience, 2020), DNA modification m6dA data analysis (Nature Neuroscience, 2019), whole-exome sequencing data analysis (Genome Medicine, 2017), and cross-ethnic meta-analysis (Nature Communications, 2017).
Journal Article: DNA G-quadruplex is a transcriptional control device that regulates memory
Marshall, Paul R., Davies, Joshua, Zhao, Qiongyi, Liau, Wei-Siang, Lee, Yujin, Basic, Dean, Periyakaruppiah, Ambika, Zajaczkowski, Esmi L., Leighton, Laura J., Madugalle, Sachithrani U., Musgrove, Mason, Kielar, Marcin, Brueckner, Arie Maeve, Gong, Hao, Ren, Haobin, Walsh, Alexander, Kaczmarczyk, Lech, Jackson, Walker S., Chen, Alon, Spitale, Robert C. and Bredy, Timothy W. (2024). DNA G-quadruplex is a transcriptional control device that regulates memory. The Journal of Neuroscience, e0093232024. doi: 10.1523/jneurosci.0093-23.2024
Journal Article: Wnt dose escalation during the exit from pluripotency identifies tranilast as a regulator of cardiac mesoderm
Wu, Zhixuan, Shen, Sophie, Mizikovsky, Dalia, Cao, Yuanzhao, Naval-Sanchez, Marina, Tan, Siew Zhuan, Alvarez, Yanina D., Sun, Yuliangzi, Chen, Xiaoli, Zhao, Qiongyi, Kim, Daniel, Yang, Pengyi, Hill, Timothy A., Jones, Alun, Fairlie, David P., Pébay, Alice, Hewitt, Alex W., Tam, Patrick P.L., White, Melanie D., Nefzger, Christian M. and Palpant, Nathan J. (2024). Wnt dose escalation during the exit from pluripotency identifies tranilast as a regulator of cardiac mesoderm. Developmental Cell. doi: 10.1016/j.devcel.2024.01.019
Hoffmann, L. B., Li, B., Wei, W., Zhao, Q., Leighton, L. J., Bredy, T. W., Pang, T. Y. and Hannan, A. J. (2023). Chronically high stress hormone levels dysregulate sperm long noncoding RNAs and their embryonic microinjection alters development and affective behaviours. Molecular Psychiatry, 1-12. doi: 10.1038/s41380-023-02350-2
(2022) NHMRC IDEAS Grants
Cell-free DNA and ALS; insight into disease mechanisms and progression
(2017–2018) Motor Neurone Disease Research Institute of Australia Inc
(2016–2017) Macquarie University
Long Noncoding RNAs: Needles or Straw in the Haystack?
(2023) Master Philosophy
Exploring the role of chromatin associated RNAs and trans splicing in learning and memory
Doctor Philosophy
DNA G-quadruplex is a transcriptional control device that regulates memory
Marshall, Paul R., Davies, Joshua, Zhao, Qiongyi, Liau, Wei-Siang, Lee, Yujin, Basic, Dean, Periyakaruppiah, Ambika, Zajaczkowski, Esmi L., Leighton, Laura J., Madugalle, Sachithrani U., Musgrove, Mason, Kielar, Marcin, Brueckner, Arie Maeve, Gong, Hao, Ren, Haobin, Walsh, Alexander, Kaczmarczyk, Lech, Jackson, Walker S., Chen, Alon, Spitale, Robert C. and Bredy, Timothy W. (2024). DNA G-quadruplex is a transcriptional control device that regulates memory. The Journal of Neuroscience, e0093232024. doi: 10.1523/jneurosci.0093-23.2024
Wu, Zhixuan, Shen, Sophie, Mizikovsky, Dalia, Cao, Yuanzhao, Naval-Sanchez, Marina, Tan, Siew Zhuan, Alvarez, Yanina D., Sun, Yuliangzi, Chen, Xiaoli, Zhao, Qiongyi, Kim, Daniel, Yang, Pengyi, Hill, Timothy A., Jones, Alun, Fairlie, David P., Pébay, Alice, Hewitt, Alex W., Tam, Patrick P.L., White, Melanie D., Nefzger, Christian M. and Palpant, Nathan J. (2024). Wnt dose escalation during the exit from pluripotency identifies tranilast as a regulator of cardiac mesoderm. Developmental Cell. doi: 10.1016/j.devcel.2024.01.019
Hoffmann, L. B., Li, B., Wei, W., Zhao, Q., Leighton, L. J., Bredy, T. W., Pang, T. Y. and Hannan, A. J. (2023). Chronically high stress hormone levels dysregulate sperm long noncoding RNAs and their embryonic microinjection alters development and affective behaviours. Molecular Psychiatry, 1-12. doi: 10.1038/s41380-023-02350-2
Fear extinction is regulated by the activity of long noncoding RNAs at the synapse
Liau, Wei-Siang, Zhao, Qiongyi, Bademosi, Adekunle, Gormal, Rachel S., Gong, Hao, Marshall, Paul R., Periyakaruppiah, Ambika, Madugalle, Sachithrani U., Zajaczkowski, Esmi L., Leighton, Laura J., Ren, Haobin, Musgrove, Mason, Davies, Joshua, Rauch, Simone, He, Chuan, Dickinson, Bryan C., Li, Xiang, Wei, Wei, Meunier, Frédéric A., Fernández-Moya, Sandra M., Kiebler, Michael A., Srinivasan, Balakumar, Banerjee, Sourav, Clark, Michael, Spitale, Robert C. and Bredy, Timothy W. (2023). Fear extinction is regulated by the activity of long noncoding RNAs at the synapse. Nature Communications, 14 (1) 7616, 1-16. doi: 10.1038/s41467-023-43535-1
Anthoney, Niki, Tainton-Heap, Lucy, Luong, Hang, Notaras, Eleni, Kewin, Amber B, Zhao, Qiongyi, Perry, Trent, Batterham, Philip, Shaw, Paul J and van Swinderen, Bruno (2023). Experimentally induced active and quiet sleep engage non-overlapping transcriptional programs in Drosophila. eLife, 12 RP88198. doi: 10.7554/elife.88198
Madugalle, Sachithrani U., Liau, Wei-Siang, Zhao, Qiongyi, Li, Xiang, Gong, Hao, Marshall, Paul R., Periyakaruppiah, Ambika, Zajaczkowski, Esmi L., Leighton, Laura J., Ren, Haobin, Musgrove, Mason R. B., Davies, Joshua W. A., Kim, Gwangmin, Rauch, Simone, He, Chuan, Dickinson, Bryan C., Fulopova, Barbora, Fletcher, Lee N., Williams, Stephen R., Spitale, Robert C. and Bredy, Timothy W. (2023). Synapse-enriched m6A-modified Malat1 interacts with the novel m6A reader, DPYSL2, and is required for fear-extinction memory. The Journal of Neuroscience, 43 (43), 7084-7100. doi: 10.1523/jneurosci.0943-23.2023
Localised Cdr1as activity is required for fear extinction memory
Lau Zajaczkowski, Esmi, Zhao, Qiongyi, Liau, Wei-Siang, Gong, Hao, Madugalle, Sachithrani Umanda, Periyakaruppiah, Ambika, Leighton, Laura Jane, Musgrove, Mason, Ren, Haobin, Davies, Joshua, Marshall, Paul Robert and Bredy, Timothy William (2023). Localised Cdr1as activity is required for fear extinction memory. Neurobiology of Learning and Memory, 203 107777, 107777. doi: 10.1016/j.nlm.2023.107777
Experimentally induced active and quiet sleep engage non-overlapping transcriptomes in Drosophila
Anthoney, Niki, Tainton-Heap, Lucy A. L., Luong, Hang, Notaras, Eleni, Zhao, Qiongyi, Perry, Trent, Batterham, Philip, Shaw, Paul J. and van Swinderen, Bruno (2023). Experimentally induced active and quiet sleep engage non-overlapping transcriptomes in Drosophila. eLife, 12. doi: 10.7554/eLife.88198.1
Wei, Wei, Zhao, Qiongyi, Wang, Ziqi, Liau, Wei-Siang, Basic, Dean, Ren, Haobin, Marshall, Paul R., Zajaczkowski, Esmi L., Leighton, Laura J., Madugalle, Sachithrani U., Musgrove, Mason, Periyakaruppiah, Ambika, Shi, Jichun, Zhang, Jianjian, Mattick, John S., Mercer, Timothy R., Spitale, Robert C., Li, Xiang and Bredy, Timothy W. (2022). ADRAM is an experience-dependent long noncoding RNA that drives fear extinction through a direct interaction with the chaperone protein 14-3-3. Cell Reports, 38 (12) 110546, 110546. doi: 10.1016/j.celrep.2022.110546
Kozulin, Peter, Zhao, Qiong-Yi, Richards, Linda, Fenlon, Laura and Suárez, Rodrigo (2022). The people behind the papers - Peter Kozulin, Rodrigo Suárez, Qiong-Yi Zhao, Linda Richards and Laura Fenlon. Development, 149 (3) dev200543. doi: 10.1242/dev.200543
Kozulin, Peter, Suárez, Rodrigo, Zhao, Qiong-Yi, Paolino, Annalisa, Richards, Linda J. and Fenlon, Laura R. (2022). Divergent evolution of developmental timing in the neocortex revealed by marsupial and eutherian transcriptomes. Development, 149 (3) dev200212. doi: 10.1242/dev.200212
Hogan, Alison L., Grima, Natalie, Fifita, Jennifer A., McCann, Emily P., Heng, Benjamin, Fat, Sandrine Chan Moi, Wu, Sharlynn, Maharjan, Ram, Cain, Amy K., Henden, Lyndal, Rayner, Stephanie, Tarr, Ingrid, Zhang, Katharine Y., Zhao, Qiongyi, Zhang, Zong-Hong, Wright, Amanda, Lee, Albert, Morsch, Marco, Yang, Shu, Williams, Kelly L. and Blair, Ian P. (2021). Splicing factor proline and glutamine rich intron retention, reduced expression and aggregate formation are pathological features of amyotrophic lateral sclerosis. Neuropathology and Applied Neurobiology, 47 (7) nan.12749, 990-1003. doi: 10.1111/nan.12749
Genome-wide microRNA profiling in brain and blood samples in a mouse model of epileptogenesis
Chen, Min, Zhao, Qiong-Yi, Edson, Janette, Zhang, Zong Hong, Li, Xiang, Wei, Wei, Bredy, Timothy and Reutens, David C. (2020). Genome-wide microRNA profiling in brain and blood samples in a mouse model of epileptogenesis. Epilepsy Research, 166 106400, 106400. doi: 10.1016/j.eplepsyres.2020.106400
Dick, Alec L. W., Zhao, Qiongyi, Crossin, Rose, Baker-Andresen, Danay, Li, Xiang, Edson, Janette, Roeh, Simone, Marshall, Victoria, Bredy, Timothy W., Lawrence, Andrew J. and Duncan, Jhodie R. (2020). Adolescent chronic intermittent toluene inhalation dynamically regulates the transcriptome and neuronal methylome within the rat medial prefrontal cortex. Addiction Biology, 26 (3) e12937, e12937. doi: 10.1111/adb.12937
Marshall, Paul R., Zhao, Qiongyi, Li, Xiang, Wei, Wei, Periyakaruppiah, Ambika, Zajaczkowski, Esmi L., Leighton, Laura J., Madugalle, Sachithrani U., Basic, Dean, Wang, Ziqi, Yin, Jiayu, Liau, Wei-Siang, Gupte, Ankita, Walkley, Carl R. and Bredy, Timothy W. (2020). Publisher Correction: Dynamic regulation of Z-DNA in the mouse prefrontal cortex by the RNA-editing enzyme Adar1 is required for fear extinction. Nature Neuroscience, 23 (8), 1034-1034. doi: 10.1038/s41593-020-0669-8
Marshall, Paul R., Zhao, Qiongyi, Li, Xiang, Wei, Wei, Periyakaruppiah, Ambika, Zajaczkowski, Esmi L., Leighton, Laura J., Madugalle, Sachithrani U., Basic, Dean, Wang, Ziqi, Yin, Jiayu, Liau, Wei-Siang, Gupte, Ankita, Walkley, Carl R. and Bredy, Timothy W. (2020). Dynamic regulation of Z-DNA in the mouse prefrontal cortex by the RNA-editing enzyme Adar1 is required for fear extinction. Nature Neuroscience, 23 (6), 718-729. doi: 10.1038/s41593-020-0627-5
Tarr, Ingrid S., McCann, Emily P., Benyamin, Beben, Peters, Timothy J., Twine, Natalie A., Zhang, Katharine Y., Zhao, Qiongyi, Zhang, Zong-Hong, Rowe, Dominic B., Nicholson, Garth A., Bauer, Denis, Clark, Susan J., Blair, Ian P. and Williams, Kelly L. (2019). Monozygotic twins and triplets discordant for amyotrophic lateral sclerosis display differential methylation and gene expression. Scientific Reports, 9 (1) 8254, 8254. doi: 10.1038/s41598-019-44765-4
Li, Xiang, Zhao, Qiongyi, Wei, Wei, Lin, Quan, Magnan, Christophe, Emami, Michael R., Wearick-Silva, Luis E., Viola, Thiago W., Marshall, Paul R., Yin, Jiayu, Madugalle, Sachithrani U., Wang, Ziqi, Nainar, Sarah, Vågbø, Cathrine Broberg, Leighton, Laura J., Zajaczkowski, Esmi L., Ke, Ke, Grassi-Oliveira, Rodrigo, Bjørås, Magnar, Baldi, Pierre F., Spitale, Robert C. and Bredy, Timothy W. (2019). The DNA modification N6-methyl-2’-deoxyadenosine (m6dA) drives activity-induced gene expression and is required for fear extinction. Nature Neuroscience, 22 (4), 534-544. doi: 10.1038/s41593-019-0339-x
Zajaczkowski, Esmi L., Zhao, Qiong-Yi, Zhang, Zong Hong, Li, Xiang, Wei, Wei, Marshall, Paul R., Leighton, Laura J., Nainar, Sarah, Feng, Chao, Spitale, Robert C. and Bredy, Timothy W. (2018). Bioorthogonal metabolic labeling of nascent RNA in neurons improves the sensitivity of transcriptome-wide profiling. ACS Chemical Neuroscience, 9 (7), 1858-1865. doi: 10.1021/acschemneuro.8b00197
Leighton, Laura J., Zhao, Qiongyi, Li, Xiang, Dai, Chuanyang, Marshall, Paul R., Liu, Sha, Wang, Yi, Zajaczkowski, Esmi L., Khandelwal, Nitin, Kumar, Arvind, Bredy, Timothy W. and Wei, Wei (2017). A Functional Role for the Epigenetic Regulator ING1 in Activity-induced Gene Expression in Primary Cortical Neurons. Neuroscience, 369, 248-260. doi: 10.1016/j.neuroscience.2017.11.018
Whole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in Chinese
Gratten, Jacob, Zhao, Qiongyi, Benyamin, Beben, Garton, Fleur, He, Ji, Leo, Paul J., Mangelsdorf, Marie, Anderson, Lisa, Zhang, Zong-Hong, Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Edson, Janette, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jin, Zi-Bing, Li, Zhongshan, Lin, Yong, Liu, Xiaolu, Marshall, Mhairi, Mowry, Bryan J., Ran, Shu, Reutens, David C., Song, Sharon, Tan, Li-Jun, Tang, Lu, Wallace, Robyn H. ... Fan, Dongsheng (2017). Whole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in Chinese. Genome Medicine, 9 (97) 97, 97. doi: 10.1186/s13073-017-0487-0
Benyamin, Beben, He, Ji, Zhao, Qiongyi, Gratten, Jacob, Garton, Fleur, Leo, Paul J., Liu, Zhijun, Mangelsdorf, Marie, Al-Chalabi, Ammar, Anderson, Lisa, Butler, Timothy J., Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Devine, Matthew, Edson, Janette, Fifita, Jennifer A., Furlong, Sarah, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jeffree, Rosalind L., Jin, Zi-Bing, Li, Zhongshan, Li, Ting, Li, Mengmeng, Lin, Yong, Liu, Xiaolu ... Fan, Dongsheng (2017). Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. Nature Communications, 8 (1) 611, 611. doi: 10.1038/s41467-017-00471-1
Garton, Fleur C., Benyamin, Beben, Zhao, Qiongyi, Liu, Zhijun, Gratten, Jacob, Henders, Anjali K., Zhang, Zong-Hong, Edson, Janette, Furlong, Sarah, Morgan, Sarah, Heggie, Susan, Thorpe, Kathryn, Pfluger, Casey, Mather, Karen A., Sachdev, Perminder S., McRae, Allan F., Robinson, Matthew R., Shah, Sonia, Visscher, Peter M., Mangelsdorf, Marie, Henderson, Robert D., Wray, Naomi R. and McCombe, Pamela A. (2017). Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort. Molecular Genetics and Genomic Medicine, 5 (4), 418-428. doi: 10.1002/mgg3.302
Widagdo, Jocelyn, Zhao, Qiong-Yi, Kempen, Marie-Jeanne, Tan, Men Chee, Ratnu, Vikram S., Wei, Wei, Leighton, Laura, Spadaro, Paola A., Edson, Janette, Anggono, Victor and Bredy, Timothy W. (2016). Experience-dependent accumulation of N6-methyladenosine in the prefrontal cortex is associated with memory processes in mice. Journal of Neuroscience, 36 (25), 6771-6777. doi: 10.1523/JNEUROSCI.4053-15.2016
De novo assembly of transcriptome from next-generation sequencing data
Li, Xuan, Kong, Yimeng, Zhao, Qiong-Yi, Li, Yuan-Yuan and Hao, Pei (2016). De novo assembly of transcriptome from next-generation sequencing data. Quantitative Biology, 4 (2), 94-105. doi: 10.1007/s40484-016-0069-y
Mapping and differential expression analysis from short-read RNA-Seq data in model organisms
Zhao, Qiong-Yi, Gratten, Jacob, Restaudi, Restuadi and Li, Xuan (2016). Mapping and differential expression analysis from short-read RNA-Seq data in model organisms. Quantitative Biology, 4 (1), 22-35. doi: 10.1007/s40484-016-0060-7
Hawi, Z., Cummins, T.D.R., Tong, J., Arcos-Burgos, M., Zhao, Q., Matthews, N., Newman, D. P., Johnson, B., Vance, A., Heussler, H. S., Levy, F., Easteal, S., Wray, N. R., Kenny, E., Morris, D., Kent, L., Gill, M. and Bellgrove, M. A. (2016). Rare DNA variants in the brain-derived neurotrophic factor gene increase risk for attention-deficit hyperactivity disorder: a next-generation sequencing study. Molecular Psychiatry, 22 (4), 580-584. doi: 10.1038/mp.2016.117
Baker-Andresen, Danay, Zhao, Qiongyi, Li, Xiang, Jupp, Bianca, Chesworth, Rose, Lawrence, Andrew J. and Bredy, Timothy (2015). Persistent variations in neuronal DNA methylation following cocaine self-administration and protracted abstinence in mice. Neuroepigenetics, 4, 1-11. doi: 10.1016/j.nepig.2015.10.001
Li, Chun-Fang, Zhu, Yan, Yu, Yao, Zhao, Qiong-Yi, Wang, Sheng-Jun, Wang, Xin-Chao, Yao, Ming-Zhe, Luo, Da, Li, Xuan, Chen, Liang and Yang, Ya-Jun (2015). Global transcriptome and gene regulation network for secondary metabolite biosynthesis of tea plant (Camellia sinensis). BMC Genomics, 16 (560) 560. doi: 10.1186/s12864-015-1773-0
Jhaveri, Dhanisha J., O'Keeffe, Imogen, Robinson, Gregory J., Zhao, Qiong-Yi, Zhang, Zong Hong, Nink, Virginia, Narayanan, Ramesh K., Osborne, Geoffrey W., Wray, Naomi R. and Bartlett, Perry F. (2015). Purification of neural precursor cells reveals the presence of distinct, stimulus-specific subpopulations of quiescent precursors in the adult mouse hippocampus. Journal of Neuroscience, 35 (21), 8132-8144. doi: 10.1523/JNEUROSCI.0504-15.2015
New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis
Lee, S. Hong, Byrne, Enda M., Hultman, Christina M., Kahler, Anna, Vinkhuyzen, Anna A. E., Ripke, Stephan, Andreassen, Ole A., Frisell, Thomas, Gusev, Alexander, Hu, Xinli, Karlsson, Robert, Mantzioris, Vasilis X., McGrath, John J., Mehta, Divya, Stahl, Eli A., Zhao, Qiongyi, Kendler, Kenneth S., Sullivan, Patrick F., Price, Alkes L., O'Donovan, Michael, Okada, Yukinori, Mowry, Bryan J., Raychaudhuri, Soumya, Wray, Naomi R., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Rheumatoid Arthritis Consortium International and Visscher, Peter M . (2015). New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. International Journal of Epidemiology, 44 (5) dyv136, 1-16. doi: 10.1093/ije/dyv136
Wang, Hua-Ling, Yang, Jiao, Boykin, Laura M., Zhao, Qiong-Yi, Wang, Yu-Jun, Liu, Shu-Sheng and Wang, Xiao-Wei (2014). Developing conversed microsatellite markers and their implications in evolutionary analysis of the Bemisia tabaci complex. Scientific Reports, 4 (1) 6351, 6351. doi: 10.1038/srep06351
Li, X., Baker-Andresen, D., Zhao, Q., Marshall, V. and Bredy, T. W. (2014). Methyl CpG Binding Domain Ultra-Sequencing: a novel method for identifying inter-individual and cell-type-specific variation in DNA methylation. Genes, Brain and Behavior, 13 (7), 721-731. doi: 10.1111/gbb.12150
A comparative study of techniques for differential expression analysis on RNA-seq data
Zhang, Zong Hong, Jhaveri, Dhanisha J., Marshall, Vikki M., Bauer, Denis C., Edson, Janette, Narayanan, Ramesh K., Robinson, Gregory J., Lundberg, Andreas E., Bartlett, Perry F., Wray, Naomi R. and Zhao, Qiong-Yi (2014). A comparative study of techniques for differential expression analysis on RNA-seq data. PLoS One, 9 (8) e103207, 1-11. doi: 10.1371/journal.pone.0103207
An, J. Y., Cristino, A. S., Zhao, Q., Edson, J., Williams, S. M., Ravine, D., Wray, J., Marshall, V. M., Hunt, A., Whitehouse, A. J. O. and Claudianos, C. (2014). Towards a molecular characterization of autism spectrum disorders: an exome sequencing and systems approach. Translational Psychiatry, 4 (6) e394, e394.1-e394.9. doi: 10.1038/tp.2014.38
Ye, Xiao-Dong, Su, Yun-Lin, Zhao, Qiong-Yi, Xia, Wen-Qiang, Liu, Shu-Sheng and Wang, Xiao-We (2014). Transcriptomic analyses reveal the adaptive features and biological differences of guts from two invasive whitefly species. BMC Genomics, 15 (1) 370. doi: 10.1186/1471-2164-15-370
Li, Xiang, Wei, Wei, Zhao, Qiong-Yi, Widagdo, Jocelyn, Baker-Andresen, Danay, Flavell, Charlotte R., D'Alessio, Ana, Zhang, Yi and Bredy, Timothy W. (2014). Neocortical Tet3-mediated accumulation of 5-hydroxymethylcytosine promotes rapid behavioral adaptation. Proceedings of the National Academy of Sciences, 111 (19), 7120-7125. doi: 10.1073/pnas.1318906111
Development of SNP and InDel markers via de novo transcriptome assembly in Sesamum indicum L
Wei, Libin, Miao, Hongmei, Li, Chun, Duan, Yinghui, Niu, Jiaojiao, Zhang, Tide, Zhao, Qiongyi and Zhang, Haiyang (2014). Development of SNP and InDel markers via de novo transcriptome assembly in Sesamum indicum L. Molecular Breeding, 34 (4), 2205-2217. doi: 10.1007/s11032-014-0174-4
Global transcriptome profiles of Camellia sinensis during cold acclimation
Wang, Xin-Chao, Zhao, Qiong-Yi, Ma, Chun-Lei, Zhang, Zong-Hong, Cao, Hong-Li, Kong, Yi-Meng, Yue, Chuan, Hao, Xin-Yuan, Chen, Liang, Ma, Jian-Qiang, Jin, Ji-Qiang, Li, Xuan and Yang, Ya-Jun (2013). Global transcriptome profiles of Camellia sinensis during cold acclimation. BMC Genomics, 14 (1) 415. doi: 10.1186/1471-2164-14-415
Wang, Hua-Ling, Yang, Jiao, Boykin, Laura M., Zhao, Qiong-Yi, Li, Qian, Wang, Xiao-Wei and Liu, Shu-Sheng (2013). The characteristics and expression profiles of the mitochondrial genome for the Mediterranean species of the Bemisia tabaci complex. BMC Genomics, 14 (1) 401. doi: 10.1186/1471-2164-14-401
Wang, Xiao-Wei, Zhao, Qiong-Yi, Luan, Jun-Bo, Wang, Yu-Jun, Yan, Gen-Hong and Liu, Shu-Sheng (2012). Analysis of a native whitefly transcriptome and its sequence divergence with two invasive whitefly species. BMC Genomics, 13 (1) 529, 529.1-529.13. doi: 10.1186/1471-2164-13-529
Alternative splicing and trans-splicing events revealed by analysis of the Bombyx mori transcriptome
Shao, Wei, Zhao, Qiong-Yi, Wang, Xiu-Ye, Xu, Xin-Yan, Tang, Qing, Li, Muwang, Li, Xuan and Xu, Yong-Zhen (2012). Alternative splicing and trans-splicing events revealed by analysis of the Bombyx mori transcriptome. RNA, 18 (7), 1395-1407. doi: 10.1261/rna.029751.111
Optimizing de novo transcriptome assembly from short-read RNA-Seq data: a comparative study
Zhao, Qiong-Yi, Wang, Yi, Kong, Yi-Meng, Luo, Da, Li, Xuan and Hao, Pei (2011). Optimizing de novo transcriptome assembly from short-read RNA-Seq data: a comparative study. BMC Bioinformatics, 12 (Suppl. 14) S2, 1-12. doi: 10.1186/1471-2105-12-S14-S2
Activity-dependent RNA methylation in learning and memory
Widagdo, J., Zhao, Q. -Y., Anggono, V. and Bredy, T. (2015). Activity-dependent RNA methylation in learning and memory. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13188
Epitranscriptomic mechanisms of memory stability
Bredy, T., Widagdo, J. and Zhao, Q.-Y. (2015). Epitranscriptomic mechanisms of memory stability. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13185
Ratnu, V., Li, X., Emami, M., Zhao, Q. -Y. and Bredy, T. (2015). Exploring the role of histone demethylase, UTX, in mediating sex differences in fear-related learning and memory. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13188
(2022) NHMRC IDEAS Grants
Cell-free DNA and ALS; insight into disease mechanisms and progression
(2017–2018) Motor Neurone Disease Research Institute of Australia Inc
(2016–2017) Macquarie University
Sporadic ALS Australian Systems Genomics Consortium (SALSA-SGC)
(2015–2019) Motor Neurone Disease Research Institute of Australia Inc
(2015) Ian Potter Foundation
Discovering deep sleep genes and determining their roles for preserving cognitive functions
(2014–2017) NHMRC Project Grant
Whole exome sequencing of sporadic MND
(2014–2015) Motor Neurone Disease Research Institute of Australia Inc
Exploring the role of chromatin associated RNAs and trans splicing in learning and memory
Doctor Philosophy — Associate Advisor
Other advisors:
Long Noncoding RNAs: Needles or Straw in the Haystack?
(2023) Master Philosophy — Associate Advisor
Other advisors: