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Dr Duy Phan

Research Fellow

Institute for Molecular Bioscience
m.phan1@uq.edu.au
+61 7 344 36267

Overview

I got my BSc degree from the University of Natural Sciences in Vietnam. I spent the next two years working on characterisation of multi-drug resistant Mycobacterium tuberculosis with Dr Maxine Caws at the Oxford University Clinical Research Unit in Ho Chi Minh City, Vietnam. I went to the Wellcome Trust Sanger Institute and the University of Cambridge, UK to do my PhD in Prof. John Wain lab where I studied molecular mechanisms affecting the stability of IncHI1 multidrug resistant plasmids in Salmonella Typhi. I then moved to Australia to join the group of Prof. Mark Schembri at the School of Chemistry and Molecular Biosciences, University of Queensland. I am now working on identifying novel virulent factors in uropathogenic E. coli, especially in the newly emerged but globally spread ST131 clone, using high-throughput transposon mutagenesis and next-gen sequencing. I also maintain my interest in plasmid biology and have started projects to study multidrug resistant plasmids carrying blaCTX-M-15 or blaNDM-1 resistant genes.

Qualifications

  • Doctor of Philosophy, University of Cambridge

Publications

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Grants

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Supervision

  • Diversity, regulation and function of the uropathogenic Escherichia coli capsule

    Doctor Philosophy

  • How bacteria form antibiotic resistant biofilms

    Doctor Philosophy

  • Understanding antibiotic resistance and virulence in uropathogenic Escherichia coli

    Doctor Philosophy

View all Supervision

Publications

Featured Publications

Journal Article

  • High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infection

    Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Hancock, Steven J., Peters, Kate M., Alvarez-Fraga, Laura, Forde, Brian M., Andersen, Stacey B., Miliya, Thyl, Harris, Patrick N. A., Beatson, Scott A., Schlebusch, Sanmarie, Bergh, Haakon, Turner, Paul, Brauner, Annelie, Westerlund-Wikström, Benita, Irwin, Adam D. and Schembri, Mark A (2024). High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infection. eLife, 12. doi: 10.7554/elife.91853.3

  • A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteria

    Nhu, Nguyen Thi Khanh, Rahman, M. Arifur, Goh, Kelvin G. K., Kim, Seung Jae, Phan, Minh-Duy, Peters, Kate M., Alvarez-Fraga, Laura, Hancock, Steven J., Ravi, Chitra, Kidd, Timothy J., Sullivan, Matthew J., Irvine, Katharine M., Beatson, Scott A., Sweet, Matthew J., Irwin, Adam D., Vukovic, Jana, Ulett, Glen C., Hasnain, Sumaira Z. and Schembri, Mark A. (2024). A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteria. Nature Communications, 15 (1) 1441, 1441. doi: 10.1038/s41467-024-45176-4

  • THIẾT LẬP VÀ ĐÁNH GIÁ QUI TRÌNH SÀNG LỌC TRƯỚC SINH KHÔNG XÂM LẤN CHO HỘI CHỨNG MẤT ĐOẠN 22Q11.2

    Nguyễn, Phạm Trường Vinh, Phạm, Thị Thuỳ Trang, Đỗ, Thị Thanh Thủy, Trương, Đình Kiệt, Tăng, Hùng Sang, Nguyễn, Hoài Nghĩa, Nguyễn, Thị Tường Vy, Giang, Hoa, Phan, Minh Duy, Nguyễn, Vạn Thông, Võ, Tá Sơn, Trần, Nhật Thăng, Nguyễn, Cảnh Chương, Tăng, Xuân Hải, Phạm, Thái Hạ, Nguyễn, Thị Bích Vân and Hà, Thị Minh Thi (2024). THIẾT LẬP VÀ ĐÁNH GIÁ QUI TRÌNH SÀNG LỌC TRƯỚC SINH KHÔNG XÂM LẤN CHO HỘI CHỨNG MẤT ĐOẠN 22Q11.2. Tạp chí Y học Việt Nam, 535 (1B). doi: 10.51298/vmj.v535i1b.8400

  • Combined functional genomic and metabolomic approaches identify new genes required for growth in human urine by multidrug-resistant <i>Escherichia coli</i> ST131

    Phan, Minh-Duy, Schirra, Horst Joachim, Nhu, Nguyen Thi Khanh, Peters, Kate M., Sarkar, Sohinee, Allsopp, Luke P., Achard, Maud E. S., Kappler, Ulrike and Schembri, Mark A. (2024). Combined functional genomic and metabolomic approaches identify new genes required for growth in human urine by multidrug-resistant Escherichia coli ST131. mBio. doi: 10.1128/mbio.03388-23

  • <i>De novo</i> variants of dominant monogenic disorders in Vietnam detected by a noninvasive prenatal test: a case series

    Tran, Nhat-Thang, Vo, Son Ta, Nguyen, Duy-Anh, Nguyen, Canh-Chuong, Dinh, Linh Thuy, Tran, Minh-Thu Thi, Tran, Danh-Cuong, Luong, Lan-Anh Thi, Doan, Kim-Phuong, Huy Nguyen, Vu Quoc, Thi Ha, Thi Minh, Truong, Linh-Giang Thi, Cao, Phuong Thi-Mai, Tran, Vy Thi-Nhat, Nhut Trinh, Thu Huong, Le, Quang Thanh, Nguyen, Van Thong, Hoang, Diem-Tuyet Thi, Nguyen, My-Nhi Ba, Bui, Chi-Thuong, Tran, Son-Tra Thi, Lam, Duc-Tam, Le, Hong-Thinh, Nguyen, My-Ngoc Ba, Ho, Viet-Thang, Nguyen, Minh-Trung, Dao, Trang Thi, Nguyen, Phuong Minh, Nguyen, Thu-Hang Le ... Tang, Hung-Sang (2023). De novo variants of dominant monogenic disorders in Vietnam detected by a noninvasive prenatal test: a case series. Personalized Medicine, 20 (6), 467-475. doi: 10.2217/pme-2023-0105

  • Characteristics and diversity of Vibrio parahaemolyticus causing acute hepatopancreatic necrosis disease in Vietnam

    Huynh, Tuan-Binh, Mai-Hoang, Thuy-Dung, Bui-Nguyen, Tram-Anh, Ha, Trinh Thi Phuong, Phan, Minh-Duy and Tran-Van, Hieu (2023). Characteristics and diversity of Vibrio parahaemolyticus causing acute hepatopancreatic necrosis disease in Vietnam. Aquaculture and Fisheries. doi: 10.1016/j.aaf.2023.10.004

  • Effects of Ocimum basilicum mucilage on hyperlipidemia and gut microbiota on mice fed a high-fat diet

    Nguyen-Le, Duy, Nguyen, Cao-Tri, Ngo-Phan, Minh-Vu, Tran, Thuoc Linh, Phan, Minh-Duy, Unno, Tatsuya and Tran-Van, Hieu (2023). Effects of Ocimum basilicum mucilage on hyperlipidemia and gut microbiota on mice fed a high-fat diet. Bioactive Carbohydrates and Dietary Fibre, 30 100384, 1-9. doi: 10.1016/j.bcdf.2023.100384

  • Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization

    Nguyen, Van Thien Chi, Nguyen, Trong Hieu, Doan, Nhu Nhat Tan, Pham, Thi Mong Quynh, Nguyen, Giang Thi Huong, Nguyen, Thanh Dat, Tran, Thuy Thi Thu, Vo, Duy Long, Phan, Thanh Hai, Jasmine, Thanh Xuan, Nguyen, Van Chu, Nguyen, Huu Thinh, Nguyen, Trieu Vu, Nguyen, Thi Hue Hanh, Huynh, Le Anh Khoa, Tran, Trung Hieu, Dang, Quang Thong, Doan, Thuy Nguyen, Tran, Anh Minh, Nguyen, Viet Hai, Nguyen, Vu Tuan Anh, Ho, Le Minh Quoc, Tran, Quang Dat, Pham, Thi Thu Thuy, Ho, Tan Dat, Nguyen, Bao Toan, Nguyen, Thanh Nhan Vo, Nguyen, Thanh Dang, Phu, Dung Thai Bieu ... Tran, Le Son (2023). Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization. eLife, 12 89083, 1-28. doi: 10.7554/eLife.89083

  • Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization

    Nguyen, Van Thien Chi, Nguyen, Trong Hieu, Doan, Nhu Nhat Tan, Pham, Thi Mong Quynh, Nguyen, Giang Thi Huong, Nguyen, Thanh Dat, Tran, Thuy Thi Thu, Vo, Duy Long, Phan, Thanh Hai, Jasmine, Thanh Xuan, Nguyen, Van Chu, Nguyen, Huu Thinh, Nguyen, Trieu Vu, Nguyen, Thi Hue Hanh, Huynh, Le Anh Khoa, Tran, Trung Hieu, Dang, Quang Thong, Doan, Thuy Nguyen, Tran, Anh Minh, Nguyen, Viet Hai, Nguyen, Vu Tuan Anh, Ho, Le Minh Quoc, Tran, Quang Dat, Pham, Thi Thu Thuy, Ho, Tan Dat, Nguyen, Bao Toan, Nguyen, Thanh Nhan Vo, Nguyen, Thanh Dang, Phu, Dung Thai Bieu ... Tran, Le Son (2023). Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization. eLife, 12. doi: 10.7554/elife.89083.3

  • Improvement in neoantigen prediction via integration of RNA sequencing data for variant calling

    Nguyen, Bui Que Tran, Tran, Thi Phuong Diem, Nguyen, Huu Thinh, Nguyen, Thanh Nhan, Pham, Thi Mong Quynh, Nguyen, Hoang Thien Phuc, Tran, Duc Huy, Nguyen, Vy, Tran, Thanh Sang, Pham, Truong-Vinh Ngoc, Le, Minh-Triet, Phan, Minh-Duy, Giang, Hoa, Nguyen, Hoai-Nghia and Tran, Le Son (2023). Improvement in neoantigen prediction via integration of RNA sequencing data for variant calling. Frontiers in Immunology, 14 1251603, 1-15. doi: 10.3389/fimmu.2023.1251603

  • Developing and validating noninvasive prenatal testing for de novo autosomal dominant monogenic diseases in Vietnam

    Nguyen, Nhi Yen, Lu, Y-Thanh, Nguyen, Duy-Anh, Nguyen, Canh-Chuong, Dinh, Linh Thuy, Tran, Minh-Thu Thi, Tran, Danh-Cuong, Luong, Lan-Anh Thi, Doan, Kim-Phuong, Huy Nguyen, Vu Quoc, Thi Ha, Thi Minh, Truong, Linh-Giang Thi, Tran, Nhat-Thang, Cao, Phuong Thi-Mai, Tran, Vy Thi-Nhat, Nhut Trinh, Thu Huong, Le, Quang Thanh, Nguyen, Van Thong, Hoang, Diem-Tuyet Thi, Vo, Son Ta, Nguyen, My-Nhi Ba, Bui, Chi-Thuong, Tran, Son-Tra Thi, Lam, Duc-Tam, Le, Hong-Thinh, Nguyen, My-Ngoc Ba, Ho, Viet-Thang, Nguyen, Minh-Trung, Doan, Phuoc-Loc ... Giang, Hoa (2023). Developing and validating noninvasive prenatal testing for de novo autosomal dominant monogenic diseases in Vietnam. Personalized Medicine, 425-433. doi: 10.2217/pme-2023-0076

  • Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization

    Tran, Le Son, Nguyen, Van Thien Chi, Nguyen, Hoai-Nghia, Giang, Hoa and Phan, Minh-Duy (2023). Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization. JCO Global Oncology, 9 (Supplement_1), 62-62. doi: 10.1200/go.2023.9.supplement_1.62

  • Genetic basis of I-complex plasmid stability and conjugation

    Lian, Zheng Jie, Phan, Minh-Duy, Hancock, Steven J., Nhu, Nguyen Thi Khanh, Paterson, David L. and Schembri, Mark A. (2023). Genetic basis of I-complex plasmid stability and conjugation. PLoS Genetics, 19 (6) e1010773, 1-21. doi: 10.1371/journal.pgen.1010773

  • Multimodal analysis of genome-wide methylation, copy number aberrations, and end motif signatures enhances detection of early-stage breast cancer

    Pham, Thi Mong Quynh, Phan, Thanh Hai, Jasmine, Thanh Xuan, Tran, Thuy Thi Thu, Huynh, Le Anh Khoa, Vo, Thi Loan, Nai, Thi Huong Thoang, Tran, Thuy Trang, Truong, My Hoang, Tran, Ngan Chau, Nguyen, Van Thien Chi, Nguyen, Trong Hieu, Nguyen, Thi Hue Hanh, Le, Nguyen Duy Khang, Nguyen, Thanh Dat, Nguyen, Duy Sinh, Truong, Dinh Kiet, Do, Thi Thanh Thuy, Phan, Minh-Duy, Giang, Hoa, Nguyen, Hoai-Nghia and Tran, Le Son (2023). Multimodal analysis of genome-wide methylation, copy number aberrations, and end motif signatures enhances detection of early-stage breast cancer. Frontiers in Oncology, 13 1127086, 1-15. doi: 10.3389/fonc.2023.1127086

  • epiTCR: a highly sensitive predictor for TCR–peptide binding

    Pham, My-Diem Nguyen, Nguyen, Thanh-Nhan, Tran, Le Son, Nguyen, Que-Tran Bui, Nguyen, Thien-Phuc Hoang, Pham, Thi Mong Quynh, Nguyen, Hoai-Nghia, Giang, Hoa, Phan, Minh-Duy and Nguyen, Vy (2023). epiTCR: a highly sensitive predictor for TCR–peptide binding. Bioinformatics, 39 (5) btad284. doi: 10.1093/bioinformatics/btad284

  • Genetic landscape and personalized tracking of tumor mutations in Vietnamese women with breast cancer

    Nguyen Hoang, Van‐Anh, Nguyen, Sao Trung, Nguyen, Trieu Vu, Pham, Thanh Huyen, Doan, Phuoc Loc, Nguyen Thi, Ngoc Thanh, Nguyen, Minh Long, Dinh, Thi Cuc, Pham, Dinh Hoang, Nguyen, Ngoc Mai, Nguyen, Duy Sinh, Nguyen, Du Quyen, Lu, Y‐Thanh, Do, Thanh Thuy Thi, Truong, Dinh Kiet, Phan, Minh‐Duy, Nguyen, Hoai‐Nghia, Giang, Hoa and Tu, Lan N (2023). Genetic landscape and personalized tracking of tumor mutations in Vietnamese women with breast cancer. Molecular Oncology, 17 (4), 598-610. doi: 10.1002/1878-0261.13356

  • Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria

    Mu, Andre, Klare, William P., Baines, Sarah L., Ignatius Pang, C. N., Guérillot, Romain, Harbison-Price, Nichaela, Keller, Nadia, Wilksch, Jonathan, Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Keller, Bernhard, Nijagal, Brunda, Tull, Dedreia, Dayalan, Saravanan, Chua, Hwa Huat Charlie, Skoneczny, Dominik, Koval, Jason, Hachani, Abderrahman, Shah, Anup D., Neha, Nitika, Jadhav, Snehal, Partridge, Sally R., Cork, Amanda J., Peters, Kate, Bertolla, Olivia, Brouwer, Stephan, Hancock, Steven J., Álvarez-Fraga, Laura, De Oliveira, David M. P. ... Walker, Mark J. (2023). Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria. Nature Communications, 14 (1) 1530, 1-21. doi: 10.1038/s41467-023-37200-w

  • Fragment length profiles of cancer mutations enhance detection of circulating tumor DNA in patients with early-stage hepatocellular carcinoma

    Nguyen, Van-Chu, Nguyen, Trong Hieu, Phan, Thanh Hai, Tran, Thanh-Huong Thi, Pham, Thu Thuy Thi, Ho, Tan Dat, Nguyen, Hue Hanh Thi, Duong, Minh-Long, Nguyen, Cao Minh, Nguyen, Que-Tran Bui, Bach, Hoai-Phuong Thi, Kim, Van-Vu, Pham, The-Anh, Nguyen, Bao Toan, Nguyen, Thanh Nhan Vo, Huynh, Le Anh Khoa, Tran, Vu Uyen, Tran, Thuy Thi Thu, Nguyen, Thanh Dang, Phu, Dung Thai Bieu, Phan, Boi Hoan Huu, Nguyen, Quynh-Tho Thi, Truong, Dinh-Kiet, Do, Thanh-Thuy Thi, Nguyen, Hoai-Nghia, Phan, Minh-Duy, Giang, Hoa and Tran, Le Son (2023). Fragment length profiles of cancer mutations enhance detection of circulating tumor DNA in patients with early-stage hepatocellular carcinoma. BMC Cancer, 23 (1) 233, 1-17. doi: 10.1186/s12885-023-10681-0

  • Circulating DNA methylation profile improves the accuracy of serum biomarkers for the detection of nonmetastatic hepatocellular carcinoma

    Phan, Thanh Hai, Chi Nguyen, Van Thien, Thi Pham, Thu Thuy, Nguyen, Van-Chu, Ho, Tan Dat, Quynh Pham, Thi Mong, Tran, Thanh-Huong, Nguyen, Thanh Dat, Khang Le, Nguyen Duy, Nguyen, Trong-Hieu, Duong, Minh-Long, Bach, Hoai-Phuong Thi, Kim, Van-Vu, Pham, The-Anh, Nguyen, Bao Toan, Vo Nguyen, Thanh Nhan, Nguyen, Thanh Dang, Bieu Phu, Dung Thai, Huu Phan, Boi Hoan, Nguyen, Duy-Sinh, Truong, Dinh-Kiet, Do, Thanh-Thuy Thi, Giang, Hoa, Nguyen, Hoai-Nghia, Phan, Minh-Duy and Tran, Le Son (2023). Circulating DNA methylation profile improves the accuracy of serum biomarkers for the detection of nonmetastatic hepatocellular carcinoma. Future Oncology, 4399-4413. doi: 10.2217/fon-2022-1218

  • Clinical validation of a ctDNA-based assay for multi-cancer detection: an interim report from a Vietnamese longitudinal prospective cohort study of 2795 participants

    Nguyen, Thi Hue Hanh, Lu, Y-Thanh, Le, Van Hoi, Bui, Vinh Quang, Nguyen, Lan Hieu, Pham, Nhu Hiep, Phan, Thanh Hai, Nguyen, Huu Thinh, Tran, Van Song, Bui, Chi Viet, Vo, Van Kha, Nguyen, Pham Thanh Nhan, Dang, Ha Huu Phuoc, Pham, Van Dung, Cao, Van Thinh, Nguyen, Thanh Dat, Nguyen, Luu Hong Dang, Phan, Ngoc Minh, Nguyen, Trong Hieu, Nguyen, Van Thien Chi, Pham, Thi Mong Quynh, Tran, Vu Uyen, Le, Minh Phong, Vo, Dac Ho, Tran, Thi Minh Thu, Nguyen, Minh Nguyen, Nguyen, Thi Thanh, Tieu, Ba Linh, Nguyen, Huu Tam Phuc ... Tran, Le Son (2023). Clinical validation of a ctDNA-based assay for multi-cancer detection: an interim report from a Vietnamese longitudinal prospective cohort study of 2795 participants. Cancer Investigation, 41 (3), 232-248. doi: 10.1080/07357907.2023.2173773

  • High prevalence of maternal mosaic monosomy X in pregnant women in Vietnam

    Tran, Danh Cuong, Nguyen, Thanh-Thanh Thi, Thi Hoang, Ngoc-Lan, Thi Luong, Lan-Anh, Doan, Kim-Phuong Thi, Ha, Minh Thi Thi, Tran, Nhat-Thang, Nguyen, Van-Thong, Trinh, Thu-Huong Nhat, Kieu Nguyen, Ngoc-Trinh, Nguyen, Cong-Trai, Nguyen, Thanh-Dat, Thi Nguyen, xQuynh-Tho, Do, Thanh-Thuy Thi, Truong, Dinh-Kiet, Giang, Hoa, Nguyen, Hoai-Nghia, Tang, Hung-Sang and Phan, Minh-Duy (2023). High prevalence of maternal mosaic monosomy X in pregnant women in Vietnam. The Journal of Maternal-Fetal and Neonatal Medicine, 36 (1) 2155044, 1-4. doi: 10.1080/14767058.2022.2155044

  • Multimodal analysis of ctDNA methylation and fragmentomic profiles enhances detection of nonmetastatic colorectal cancer

    Nguyen, Huu Thinh, Khoa Huynh, Le Anh, Nguyen, Trieu Vu, Tran, Duc Huy, Thu Tran, Thuy Thi, Khang Le, Nguyen Duy, Le, Ngoc-An Trinh, Pham, Truong-Vinh Ngoc, Le, Minh-Triet, Quynh Pham, Thi Mong, Nguyen, Trong Hieu, Van Nguyen, Thien Chi, Nguyen, Thanh Dat, Tran Nguyen, Bui Que, Phan, Minh-Duy, Giang, Hoa and Tran, Le Son (2022). Multimodal analysis of ctDNA methylation and fragmentomic profiles enhances detection of nonmetastatic colorectal cancer. Future Oncology, 18 (35), 3895-3912. doi: 10.2217/fon-2022-1041

  • Detection of maternal carriers of common α-thalassemia deletions from cell-free DNA

    Doan, Phuoc-Loc, Nguyen, Duy-Anh, Le, Quang Thanh, Hoang, Diem-Tuyet Thi, Nguyen, Huu Du, Nguyen, Canh Chuong, Doan, Kim Phuong Thi, Tran, Nhat Thang, Ha, Thi Minh Thi, Trinh, Thu Huong Nhat, Nguyen, Van Thong, Bui, Chi Thuong, Lai, Ngoc-Diep Thi, Duong, Thanh Hien, Mai, Hai-Ly, Huynh, Pham-Uyen Vinh, Huynh, Thu Thanh Thi, Le, Quang Vinh, Vo, Thanh Binh, Dao, Thi Hong-Thuy, Vo, Phuong Anh, Le, Duy-Khang Nguyen, Tran, Ngoc Nhu Thi, Tran, Quynh Nhu Thi, Van, Yen-Linh Thi, Tran, Huyen-Trang Thi, Nguyen, Hoai Thi, Nguyen, Phuong-Uyen, Do, Thanh-Thuy Thi ... Phan, Minh-Duy (2022). Detection of maternal carriers of common α-thalassemia deletions from cell-free DNA. Scientific Reports, 12 (1) 13581, 1-9. doi: 10.1038/s41598-022-17718-7

  • Tần suất và phổ đột biến gen của Hội chứng ung thư vú và buồng trứng di truyền trên quần thể người Việt Nam

    Nguyễn, Lưu Hồng Đăng, Tăng, Hùng Sang, Phan, Ngọc Minh, Nguyễn, Thị Thanh, Nguyễn, Dư Quyền, Tiêu, Bá Linh, Nguyễn, Thị Huệ Hạnh, Nguyễn, Yến Nhi, Trần, Vũ Uyên, Lê, Minh Phong, Nguyễn, Duy Sinh, Phan, Minh Duy, Từ, Ngọc Ly Lan, Giang, Hoa, Nguyễn, Hoài Nghĩa, Trương, Đình Kiệt and Đỗ, Thị Thanh Thủy (2022). Tần suất và phổ đột biến gen của Hội chứng ung thư vú và buồng trứng di truyền trên quần thể người Việt Nam. Tạp chí Phụ sản, 20 (3), 130-135. doi: 10.46755/vjog.2022.3.1433

  • Fitness effects of blaCTX-M-15-harbouring F2:A1:B− plasmids on their native Escherichia coli ST131 H30Rx hosts

    Palkovicova, Jana, Sukkar, Iva, Delafuente, Javier, Valcek, Adam, Medvecky, Matej, Jamborova, Ivana, Bitar, Ibrahim, Phan, Minh Duy, San Millan, Alvaro and Dolejska, Monika (2022). Fitness effects of blaCTX-M-15-harbouring F2:A1:B− plasmids on their native Escherichia coli ST131 H30Rx hosts. Journal of Antimicrobial Chemotherapy, 77 (11), 2960-2963. doi: 10.1093/jac/dkac250

  • Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli

    Hancock, Steven J., Lo, Alvin W., Ve, Thomas, Day, Christopher J., Tan, Lendl, Mendez, Alejandra A., Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Peters, Kate M., Richards, Amanda C., Fleming, Brittany A., Chang, Chyden, Ngu, Dalton H. Y., Forde, Brian M., Haselhorst, Thomas, Goh, Kelvin G. K., Beatson, Scott A., Jennings, Michael P., Mulvey, Matthew A., Kobe, Bostjan and Schembri, Mark A. (2022). Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli. PLoS Pathogens , 18 (6) e1010582, e1010582. doi: 10.1371/journal.ppat.1010582

  • Gut–bladder axis in recurrent UTI

    Schembri, Mark A., Nhu, Nguyen Thi Khanh and Phan, Minh-Duy (2022). Gut–bladder axis in recurrent UTI. Nature Microbiology, 7 (5), 601-602. doi: 10.1038/s41564-022-01113-z

  • Differential Afa/Dr fimbriae expression in the multidrug-resistant Escherichia coli ST131 clone

    Alvarez-Fraga, Laura, Phan, Minh-Duy, Goh, Kelvin G. K., Nhu, Nguyen Thi Khanh, Hancock, Steven J., Allsopp, Luke P., Peters, Kate M., Forde, Brian M., Roberts, Leah W., Sullivan, Matthew J., Totsika, Makrina, Beatson, Scott A., Ulett, Glen C. and Schembri, Mark A. (2022). Differential Afa/Dr fimbriae expression in the multidrug-resistant Escherichia coli ST131 clone. mBio, 13 (1) e03519, e0351921. doi: 10.1128/mbio.03519-21

  • Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131

    Phan, Minh-Duy, Peters, Kate M., Alvarez Fraga, Laura, Wallis, Steven C., Hancock, Steven, Nhu, Nguyen Thi Khanh, Forde, Brian, Bauer, Michelle J., Paterson, David L., Beatson, Scott A, Lipman, Jeffrey and Schembri, Mark A. (2022). Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131. Antimicrobial Agents and Chemotherapy, 66 (1) e02146-21, 1-11. doi: 10.1128/aac.02146-21

  • Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection

    De Oliveira, David M. P., Forde, Brian M., Phan, Minh-Duy, Steiner, Bernhard, Zhang, Bing, Zuegg, Johannes, El-deeb, Ibrahim M., Li, Gen, Keller, Nadia, Brouwer, Stephan, Harbison-Price, Nichaela, Cork, Amanda J., Bauer, Michelle J., Alquethamy, Saleh F., Beatson, Scott A., Roberts, Jason A., Paterson, David L., McEwan, Alastair G., Blaskovich, Mark A. T., Schembri, Mark A., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2022). Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection. mBio, 13 (1) e03517, e0351721. doi: 10.1128/mbio.03517-21

  • Pathogenic Variant Profile of Hereditary Cancer Syndromes in a Vietnamese Cohort

    Tran, Van Thuan, Nguyen, Sao Trung, Pham, Xuan Dung, Phan, Thanh Hai, Nguyen, Van Chu, Nguyen, Huu Thinh, Nguyen, Huu Phuc, Doan, Phuong Thao Thi, Le, Tuan Anh, Nguyen, Bao Toan, Jasmine, Thanh Xuan, Nguyen, Duy Sinh, Nguyen, Hong-Dang Luu, Nguyen, Ngoc Mai, Do, Duy Xuan, Tran, Vu Uyen, Nguyen, Hue Hanh Thi, Le, Minh Phong, Nguyen, Yen Nhi, Do, Thanh Thuy Thi, Truong, Dinh Kiet, Tang, Hung Sang, Phan, Minh-Duy, Nguyen, Hoai-Nghia, Giang, Hoa and Tu, Lan N. (2022). Pathogenic Variant Profile of Hereditary Cancer Syndromes in a Vietnamese Cohort. Frontiers in Oncology, 11 789659. doi: 10.3389/fonc.2021.789659

  • Combined Gap-Polymerase Chain Reaction and Targeted Next-Generation Sequencing Improve α- and β-Thalassemia Carrier Screening in Pregnant Women in Vietnam

    Lam, Tuan-Thanh, Nguyen, Doan-Tu, Le, Quang Thanh, Nguyen, Duy-Anh, Hoang, Diem-Tuyet Thi, Nguyen, Huu Du, Nguyen, Canh Chuong, Doan, Kim Phuong Thi, Tran, Nhat-Thang, Ha, Thi Minh Thi, Trinh, Thu Huong Nhat, Nguyen, Van Thong, Lam, Duc Tam, Le, Minh Tam, Nguyen, Xuan Thao, Ho, Thu-Hang Thi, Tran, Trung Hoanh, Ho, Viet Thang, Bui, Thanh Van, Nguyen, Van Trong, Hoang, Phuoc Ba, Nguyen, Hoai Thanh, Nguyen, Manh Hoan, Vo, Thanh-Binh, Le, Duy-Khang Nguyen, Truong, Thao Ngoc, Dao, Hong-Thuy Thi, Vo, Phuong-Anh Ngoc, Nguyen, Thien-Chi Van ... Nguyen, Hoai-Nghia (2022). Combined Gap-Polymerase Chain Reaction and Targeted Next-Generation Sequencing Improve α- and β-Thalassemia Carrier Screening in Pregnant Women in Vietnam. Hemoglobin, 46 (4), 233-239. doi: 10.1080/03630269.2022.2096461

  • Massively parallel sequencing uncovered disease-associated variant spectra of glucose-6-phosphate dehydrogenase deficiency, phenylketonuria and galactosemia in Vietnamese pregnant women

    Nguyen, Tat-Thanh, Le, Quang-Thanh, Hoang, Diem-Tuyet Thi, Du Nguyen, Huu, Ha, Thi Minh Thi, Nguyen, My-Nhi Ba, Ta, Thanh-Thuy Thi, Tran, Nhat Thang, Trinh, Thu Huong Nhat, Doan, Kim Phuong Thi, Lam, Duc Tam, Tran, Son Tra Thi, Nguyen, Thanh Xuan, Le, Hong-Thinh, Ha, Van Tuan, Nguyen, Manh Hoan, Le, Ba-Liem Kim, Duong, My Linh, Pham, Trung Ha, Tran, Anh Tuan, Phan, Xuan Lan Thi, Huynh, Thanh Liem, Nguyen, Lan-Phuong Thi, Vo, Thanh Binh, Le, Duy-Khang Nguyen, Tran, Ngoc Nhu Thi, Tran, Quynh Nhu Thi, Van, Yen-Linh Thi, Huynh, Bich-Ngoc Thi ... Giang, Hoa (2022). Massively parallel sequencing uncovered disease-associated variant spectra of glucose-6-phosphate dehydrogenase deficiency, phenylketonuria and galactosemia in Vietnamese pregnant women. Molecular Genetics and Genomic Medicine, 10 (7) e1959. doi: 10.1002/mgg3.1959

  • Modified horseshoe crab peptides target and kill bacteria inside host cells

    Amiss, Anna S., von Pein, Jessica B., Webb, Jessica R., Condon, Nicholas D., Harvey, Peta J., Phan, Minh-Duy, Schembri, Mark A., Currie, Bart J., Sweet, Matthew J., Craik, David J., Kapetanovic, Ronan, Henriques, Sónia Troeira and Lawrence, Nicole (2021). Modified horseshoe crab peptides target and kill bacteria inside host cells. Cellular and Molecular Life Sciences, 79 (1) 38, 38. doi: 10.1007/s00018-021-04041-z

  • Ultra-deep sequencing of plasma-circulating DNA for the detection of tumor- derived mutations in patients with nonmetastatic colorectal cancer

    Nguyen, Huu-Thinh, Luong, Bac An, Tran, Duc-Huy, Nguyen, Trong-Hieu, Ngo, Quoc Dat, Le, Linh Gia Hoang, Ho, Quoc Chuong, Nguyen, Hue-Hanh Thi, Nguyen, Cao Minh, Tran, Vu Uyen, Pham, Truong Vinh Ngoc, Le, Minh Triet, Le, Ngoc An Trinh, Le, Trung Kien, Nguyen, Thanh Luan, Pham, Hong-Anh Thi, Le, Hong Thuy, Duong, Hong Diep Thi, Hoang, Anh Vu, Nguyen, Hoang Bac, Dinh, Kiet Truong, Phan, Minh-Duy, Nguyen, Hoai-Nghia, Do, Thanh-Thuy Thi, Giang, Hoa, Tran, Le Son and Tran, Diep Tuan (2021). Ultra-deep sequencing of plasma-circulating DNA for the detection of tumor- derived mutations in patients with nonmetastatic colorectal cancer. Cancer Investigation, 40 (4), 1-12. doi: 10.1080/07357907.2021.2017951

  • Liquid biopsy uncovers distinct patterns of DNA methylation and copy number changes in NSCLC patients with different EGFR-TKI resistant mutations

    Nguyen, Hoai-Nghia, Cao, Ngoc-Phuong Thi, Van Nguyen, Thien-Chi, Le, Khang Nguyen Duy, Nguyen, Dat Thanh, Nguyen, Quynh-Tho Thi, Nguyen, Thai-Hoa Thi, Van Nguyen, Chu, Le, Ha Thu, Nguyen, Mai-Lan Thi, Nguyen, Trieu Vu, Tran, Vu Uyen, Luong, Bac An, Le, Linh Gia Hoang, Ho, Quoc Chuong, Pham, Hong-Anh Thi, Vo, Binh Thanh, Nguyen, Luan Thanh, Dang, Anh-Thu Huynh, Nguyen, Sinh Duy, Do, Duc Minh, Do, Thanh-Thuy Thi, Hoang, Anh Vu, Dinh, Kiet Truong, Phan, Minh-Duy, Giang, Hoa and Tran, Le Son (2021). Liquid biopsy uncovers distinct patterns of DNA methylation and copy number changes in NSCLC patients with different EGFR-TKI resistant mutations. Scientific Reports, 11 (1) 16436, 1-12. doi: 10.1038/s41598-021-95985-6

  • Genetic landscape of recessive diseases in the Vietnamese population from large‐scale clinical exome sequencing

    Tran, Ngoc Hieu, Nguyen Thi, Thanh‐Huong, Tang, Hung‐Sang, Hoang, Le‐Phuc, Le Nguyen, Trung‐Hieu, Tran, Nhat‐Thang, Trinh, Thu‐Huong Nhat, Nguyen, Van Thong, Nguyen, Bao‐Han Huu, Nguyen, Hieu Trong, Doan, Loc Phuoc, Phan, Ngoc‐Minh, Thi Nguyen, Kim‐Huong, Nguyen, Hong‐Dang Luu, Thi Quach, Minh‐Tam, Thi Nguyen, Thanh‐Phuong, Tran, Vu Uyen, Tran, Dinh‐Vinh, Thi Nguyen, Quynh‐Tho, Thi Do, Thanh‐Thuy, Lam, Nien Vinh, Thi Ngoc, Phuong Cao, Truong, Dinh Kiet, Nguyen, Hoai‐Nghia, Phan, Minh‐Duy and Giang, Hoa (2021). Genetic landscape of recessive diseases in the Vietnamese population from large‐scale clinical exome sequencing. Human Mutation, 42 (10) humu.24253, 1-10. doi: 10.1002/humu.24253

  • Characterisation of DtrJ as an IncC plasmid conjugative DNA transfer component

    Hancock, Steven J., Phan, Minh‐Duy, Roberts, Leah, Vu, Thu Ngoc Minh, Harris, Patrick N.A., Beatson, Scott A. and Schembri, Mark A. (2021). Characterisation of DtrJ as an IncC plasmid conjugative DNA transfer component. Molecular Microbiology, 116 (1), 154-167. doi: 10.1111/mmi.14697

  • MicroPIPE: validating an end-to-end workflow for high-quality complete bacterial genome construction

    Murigneux, Valentine, Roberts, Leah W., Forde, Brian M., Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Irwin, Adam D., Harris, Patrick N. A., Paterson, David L., Schembri, Mark A., Whiley, David M. and Beatson, Scott A. (2021). MicroPIPE: validating an end-to-end workflow for high-quality complete bacterial genome construction. BMC Genomics, 22 (1) 474, 474. doi: 10.1186/s12864-021-07767-z

  • Genetic analysis of Vietnamese patients with early-onset Alzheimer's disease

    Tong, Trang Mai, Dao, Thuy Thi Hong, Doan, Loc Phuoc, Nguyen, Dat Thanh, Nguyen, Quynh-Tho Thi, Do, Thanh-Thuy Thi, Truong, Kiet Dinh, Phan, Minh-Duy, Nguyen, Hoai-Nghia, Tran, Thang Cong and Giang, Hoa (2021). Genetic analysis of Vietnamese patients with early-onset Alzheimer's disease. International Journal of Neuroscience, 132 (12), 1-8. doi: 10.1080/00207454.2020.1870974

  • Actionable Mutation Profiles of Non-Small Cell Lung Cancer patients from Vietnamese population

    Dang, Anh-Thu Huynh, Tran, Vu-Uyen, Tran, Thanh-Truong, Thi Pham, Hong-Anh, Le, Dinh-Thong, Nguyen, Lam, Nguyen, Ngoc-Vu, Thi Nguyen, Thai-Hoa, Nguyen, Chu Van, Le, Ha Thu, Thi Nguyen, Mai-Lan, Le, Vu Thuong, Nguyen, Phuc Huu, Vo, Binh Thanh, Thi Dao, Hong-Thuy, Nguyen, Luan Thanh, Van Nguyen, Thien-Chi, Bui, Quynh-Tram Nguyen, Nguyen, Long Hung, Nguyen, Nguyen Huu, Thi Nguyen, Quynh-Tho, Le, Truong Xuan, Do, Thanh-Thuy Thi, Dinh, Kiet Truong, Do, Han Ngoc, Phan, Minh-Duy, Nguyen, Hoai-Nghia, Tran, Le Son and Giang, Hoa (2020). Actionable Mutation Profiles of Non-Small Cell Lung Cancer patients from Vietnamese population. Scientific Reports, 10 (1) 2707, 2707. doi: 10.1038/s41598-020-59744-3

  • Genetic profiling of Vietnamese population from large-scale genomic analysis of non-invasive prenatal testing data

    Tran, Ngoc Hieu, Vo, Thanh Binh, Nguyen, Van Thong, Tran, Nhat-Thang, Trinh, Thu-Huong Nhat, Pham, Hong-Anh Thi, Dao, Thi Hong Thuy, Nguyen, Ngoc Mai, Van, Yen-Linh Thi, Tran, Vu Uyen, Vu, Hoang Giang, Bui, Quynh-Tram Nguyen, Vo, Phuong-Anh Ngoc, Nguyen, Huu Nguyen, Nguyen, Quynh-Tho Thi, Do, Thanh-Thuy Thi, Lam, Nien Vinh, Ngoc, Phuong Cao Thi, Truong, Dinh Kiet, Nguyen, Hoai-Nghia, Giang, Hoa and Phan, Minh-Duy (2020). Genetic profiling of Vietnamese population from large-scale genomic analysis of non-invasive prenatal testing data. Scientific Reports, 10 (1) 19142, 1-8. doi: 10.1038/s41598-020-76245-5

  • Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis

    De Oliveira, David M. P., Bohlmann, Lisa, Conroy, Trent, Jen, Freda E.-C., Everest-Dass, Arun, Hansford, Karl A., Bolisetti, Raghu, El-Deeb, Ibrahim M., Forde, Brian M., Phan, Minh-Duy, Lacey, Jake A., Tan, Aimee, Rivera-Hernandez, Tania, Brouwer, Stephan, Keller, Nadia, Kidd, Timothy J., Cork, Amanda J., Bauer, Michelle J., Cook, Gregory M., Davies, Mark R., Beatson, Scott A., Paterson, David L., McEwan, Alastair G., Li, Jian, Schembri, Mark A., Blaskovich, Mark A. T., Jennings, Michael P., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2020). Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis. Science Translational Medicine, 12 (570) abb3791, eabb3791. doi: 10.1126/scitranslmed.abb3791

  • Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB

    Hancock, Steven J., Phan, Minh-Duy, Luo, Zhenyao, Lo, Alvin W., Peters, Kate M., Nhu, Nguyen Thi Khanh, Forde, Brian M., Whitfield, Jason, Yang, Ji, Strugnell, Richard A., Paterson, David L., Walsh, Timothy R., Kobe, Bostjan, Beatson, Scott A. and Schembri, Mark A. (2020). Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB. Nature Microbiology, 5 (11), 1340-1348. doi: 10.1038/s41564-020-0775-0

  • Ultra-Deep Massive Parallel Sequencing of Plasma Cell-Free DNA Enables Large-Scale Profiling of Driver Mutations in Vietnamese Patients With Advanced Non-Small Cell Lung Cancer

    Tran, Le Son, Nguyen, Quynh-Tho Thi, Nguyen, Chu Van, Tran, Vu-Uyen, Nguyen, Thai-Hoa Thi, Le, Ha Thu, Nguyen, Mai-Lan Thi, Le, Vu Thuong, Pham, Lam-Son, Vo, Binh Thanh, Dang, Anh-Thu Huynh, Nguyen, Luan Thanh, Nguyen, Thien-Chi Van, Pham, Hong-Anh Thi, Tran, Thanh-Truong, Nguyen, Long Hung, Nguyen, Thanh-Thanh Thi, Nguyen, Kim-Huong Thi, Vu, Yen-Vi, Nguyen, Nguyen Huu, Bui, Vinh-Quang, Bui, Hai-Ha, Do, Thanh-Thuy Thi, Lam, Nien Vinh, Truong Dinh, Kiet, Phan, Minh-Duy, Nguyen, Hoai-Nghia and Giang, Hoa (2020). Ultra-Deep Massive Parallel Sequencing of Plasma Cell-Free DNA Enables Large-Scale Profiling of Driver Mutations in Vietnamese Patients With Advanced Non-Small Cell Lung Cancer. Frontiers in Oncology, 10 1351. doi: 10.3389/fonc.2020.01351

  • Frontline Science: LPS‐inducible SLC30A1 drives human macrophage‐mediated zinc toxicity against intracellular Escherichia coli

    Stocks, Claudia J., Pein, Jessica B., Curson, James E.B., Rae, James, Phan, Minh‐Duy, Foo, Darren, Bokil, Nilesh J., Kambe, Taiho, Peters, Kate M., Parton, Robert G., Schembri, Mark A., Kapetanovic, Ronan and Sweet, Matthew J. (2020). Frontline Science: LPS‐inducible SLC30A1 drives human macrophage‐mediated zinc toxicity against intracellular Escherichia coli. Journal of Leukocyte Biology, 109 (2) JLB.2HI0420-160R, 287-297. doi: 10.1002/jlb.2hi0420-160r

  • Uncovering novel susceptibility targets to enhance the efficacy of third-generation cephalosporins against ESBL-producing uropathogenic Escherichia coli

    Phan, Minh-Duy, Bottomley, Amy L., Peters, Kate M., Harry, Elizabeth J. and Schembri, Mark A. (2020). Uncovering novel susceptibility targets to enhance the efficacy of third-generation cephalosporins against ESBL-producing uropathogenic Escherichia coli. Journal of Antimicrobial Chemotherapy, 75 (6), 1415-1423. doi: 10.1093/jac/dkaa023

  • TraDIS-Xpress: a high-resolution whole-genome assay identifies novel mechanisms of triclosan action and resistance

    Yasir, Muhammad, Turner, A Keith, Bastkowski, Sarah, Baker, David, Page, Andrew J., Telatin, Andrea, Phan, Minh-Duy, Monahan, Leigh, Savva, George M., Darling, Aaron, Webber, Mark A. and Charles, Ian G. (2020). TraDIS-Xpress: a high-resolution whole-genome assay identifies novel mechanisms of triclosan action and resistance. Genome Research, 30 (2), 239-249. doi: 10.1101/gr.254391.119

  • Integrating multiple genomic technologies to investigate an outbreak of carbapenemase-producing Enterobacter hormaechei

    Roberts, Leah W., Harris, Patrick N. A., Forde, Brian M., Ben Zakour, Nouri L., Catchpoole, Elizabeth, Stanton-Cook, Mitchell, Phan, Minh-Duy, Sidjabat, Hanna E., Bergh, Haakon, Heney, Claire, Gawthorne, Jayde A., Lipman, Jeffrey, Allworth, Anthony, Chan, Kok-Gan, Chong, Teik Min, Yin, Wai-Fong, Schembri, Mark A., Paterson, David L. and Beatson, Scott A. (2020). Integrating multiple genomic technologies to investigate an outbreak of carbapenemase-producing Enterobacter hormaechei. Nature Communications, 11 (1) 466, 466. doi: 10.1038/s41467-019-14139-5

  • Evaluation of a liquid biopsy protocol using ultra-deep massive parallel sequencing for detecting and quantifying circulation tumor DNA in colorectal cancer patients

    Nguyen, Huu Thinh, Tran, Duc Huy, Ngo, Quoc Dat, Pham, Hong-Anh Thi, Tran, Thanh-Truong, Tran, Vu-Uyen, Pham, Truong-Vinh Ngoc, Le, Trung Kien, Le, Ngoc-An Trinh, Nguyen, Ngoc Mai, Vo, Binh Thanh, Nguyen, Luan Thanh, Nguyen, Thien-Chi Van, Bui, Quynh Tram Nguyen, Nguyen, Huu-Nguyen, Le, Linh Gia Hoang, Do, Duc Minh, Do, Thanh-Thuy Thi, Truong Dinh, Kiet, Phan, Minh-Duy, Tran, Le Son, Giang, Hoa and Nguyen, Hoai-Nghia (2020). Evaluation of a liquid biopsy protocol using ultra-deep massive parallel sequencing for detecting and quantifying circulation tumor DNA in colorectal cancer patients. Cancer Investigation, 38 (2), 1-9. doi: 10.1080/07357907.2020.1713350

  • Ultra-deep massively parallel sequencing with unique molecular identifier tagging achieves comparable performance to droplet digital PCR for detection and quantification of circulating tumor DNA from lung cancer patients

    Tran, Le Son, Pham, Hong-Anh Thi, Tran, Vu-Uyen, Tran, Thanh-Truong, Dang, Anh-Thu Huynh, Le, Dinh-Thong, Nguyen, Son-Lam, Nguyen, Ngoc-Vu, Nguyen, Trieu-Vu, Vo, Binh Thanh, Dao, Hong-Thuy Thi, Nguyen, Nguyen Huu, Tran, Tam Huu, Nguyen, Chu Van, Pham, Phuong Cam, Dang-Mai, Anh Tuan, Dinh-Nguyen, Thien Kim, Phan, Van Hieu, Do, Thanh-Thuy Thi, Truong Dinh, Kiet, Do, Han Ngoc, Phan, Minh-Duy, Giang, Hoa and Nguyen, Hoai-Nghia (2019). Ultra-deep massively parallel sequencing with unique molecular identifier tagging achieves comparable performance to droplet digital PCR for detection and quantification of circulating tumor DNA from lung cancer patients. PLoS One, 14 (12) e0226193., e0226193. doi: 10.1371/journal.pone.0226193

  • Complex multilevel control of hemolysin production by uropathogenic Escherichia coli

    Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Forde, Brian M., Murthy, Ambika M. V., Peters, Kate M., Day, Christopher J., Poole, Jessica, Kidd, Timothy J., Welch, Rodney A., Jennings, Michael P., Ulett, Glen C., Sweet, Matthew J., Beatson, Scott A. and Schembri, Mark A. (2019). Complex multilevel control of hemolysin production by uropathogenic Escherichia coli. mBio, 10 (5) e02248-19. doi: 10.1128/mbio.02248-19

  • Bioinformatic and molecular analysis of inverse autotransporters from Escherichia coli

    Goh, Kelvin G. K., Moriel, Danilo G., Hancock, Steven J., Phan, Minh-Duy and Schembri, Mark A. (2019). Bioinformatic and molecular analysis of inverse autotransporters from Escherichia coli. MSphere, 4 (4) e00572-19. doi: 10.1128/msphere.00572-19

  • Population dynamics of an Escherichia coli ST131 lineage during recurrent urinary tract infection

    Forde, Brian M., Roberts, Leah W., Phan, Minh-Duy, Peters, Kate M., Fleming, Brittany A., Russell, Colin W., Lenherr, Sara M., Myers, Jeremy B., Barker, Adam P., Fisher, Mark A., Chong, Teik-Min, Yin, Wai-Fong, Chan, Kok-Gan, Schembri, Mark A., Mulvey, Matthew A. and Beatson, Scott A. (2019). Population dynamics of an Escherichia coli ST131 lineage during recurrent urinary tract infection. Nature Communications, 10 (1) 3643, 3643. doi: 10.1038/s41467-019-11571-5

  • Mycobacterium tuberculosis requires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism

    Serafini, Agnese, Tan, Lendl, Horswell, Stuart, Howell, Steven, Greenwood, Daniel J., Hunt, Deborah M., Phan, Minh-Duy, Schembri, Mark, Monteleone, Mercedes, Montague, Christine R., Britton, Warwick, Garza-Garcia, Acely, Snijders, Ambrosius P., VanderVen, Brian, Gutierrez, Maximiliano G., West, Nicholas P. and de Carvalho, Luiz Pedro S. (2019). Mycobacterium tuberculosis requires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism. Molecular Microbiology, 112 (4) mmi.14362, 1284-1307. doi: 10.1111/mmi.14362

  • Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules

    Paxman, Jason J., Lo, Alvin W., Sullivan, Matthew J., Panjikar, Santosh, Kuiper, Michael, Whitten, Andrew E., Wang, Geqing, Luan, Chi-Hao, Moriel, Danilo G., Tan, Lendl, Peters, Kate M., Phan, Minh-Duy, Gee, Christine L., Ulett, Glen C., Schembri, Mark A. and Heras, Begoña (2019). Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules. Nature Communications, 10 (1) 1967, 1967. doi: 10.1038/s41467-019-09814-6

  • Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination

    Stocks, Claudia J., Phan, Minh-Duy, Achard, Maud E. S., Nhu, Nguyen Thi Khanh, Condon, Nicholas D., Gawthorne, Jayde A., Lo, Alvin W., Peters, Kate M., McEwan, Alastair G., Kapetanovic, Ronan, Schembri, Mark A. and Sweet, Matthew J. (2019). Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination. Proceedings of the National Academy of Sciences, 116 (13), 6341-6350. doi: 10.1073/pnas.1820870116

  • Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization

    Murthy, Ambika M. V., Sullivan, Matthew J., Nhu, Nguyen Thi Khanh, Lo, Alvin W., Phan, Minh-Duy, Peters, Kate M., Boucher, Dave, Schroder, Kate, Beatson, Scott A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2019). Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization. FASEB Journal : official publication of the Federation of American Societies for Experimental Biology, 33 (6), fj201802100R-7450. doi: 10.1096/fj.201802100R

  • Reducing false positive rate of fetal monosomy X in non‐invasive prenatal testing using a combined algorithm to detect maternal mosaic monosomy X

    Phan, Minh‐Duy, Vo, Binh T., Nguyen, Thong V., Tran, Thang N., Trinh, Huong N.T., Nguyen, Tho T.Q., Nguyen, Nguyen H., Tran, Truong T., Tran, Uyen V., Dao, Thuy H., Pham, Anh H., Tran, Tam H., Truong, Kiet D., Hoang, Tuyet T.D., Do, Thuy T.T., Nguyen, Hoai‐Nghia and Giang, Hoa (2019). Reducing false positive rate of fetal monosomy X in non‐invasive prenatal testing using a combined algorithm to detect maternal mosaic monosomy X. Prenatal Diagnosis, 39 (4) pd.5430, 324-327. doi: 10.1002/pd.5430

  • Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance

    Bohlmann, Lisa, De Oliveira, David M. P., El-Deeb, Ibrahim M., Brazel, Erin B., Harbison-Price, Nichaela, Ong, Cheryl-lynn Y., Rivera-Hernandez, Tania, Ferguson, Scott A., Cork, Amanda J., Phan, Minh-Duy, Soderholm, Amelia T., Davies, Mark R., Nimmo, Graeme R., Dougan, Gordon, Schembri, Mark A., Cook, Gregory M., McEwan, Alastair G., von Itzstein, Mark, McDevitt, Christopher A. and Walker, Mark J. (2018). Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance. mBio, 9 (6) e02391-18, 1-12. doi: 10.1128/mBio.02391-18

  • Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance

    Bohlmann, Lisa, De Oliveira, David M. P., El-Deeb, Ibrahim M., Brazel, Erin B., Harbison-Price, Nichaela, Ong, Cheryl-lynn Y., Rivera-Hernandez, Tania, Ferguson, Scott A., Cork, Amanda J., Phan, Minh-Duy, Soderholm, Amelia T., Davies, Mark R., Nimmo, Graeme R., Dougan, Gordon, Schembri, Mark A., Cook, Gregory M., McEwan, Alastair G., von Itzstein, Mark, McDevitt, Christopher A. and Walker, Mark J. (2018). Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance. mBio, 9 (6) e02391-18. doi: 10.1128/mbio.02391-18

  • Detection of a heterozygous germline APC mutation in a three-generation family with familial adenomatous polyposis using targeted massive parallel sequencing in Vietnam

    Giang, Hoa, Nguyen, Vu T., Nguyen, Sinh D., Nguyen, Huu-Phuc, Vo, Binh T., Nguyen, Truc M., Nguyen, Nguyen H., Truong, Kiet D., Do, Thanh-Thuy T., Phan, Minh-Duy and Nguyen, Hoai-Nghia (2018). Detection of a heterozygous germline APC mutation in a three-generation family with familial adenomatous polyposis using targeted massive parallel sequencing in Vietnam. BMC Medical Genetics, 19 (1) 188. doi: 10.1186/s12881-018-0701-y

  • Discovery of new genes involved in curli production by a uropathogenic Escherichia coli strain from the highly virulent O45:K1:H7 lineage

    Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Peters, Kate M., Lo, Alvin W., Forde, Brian M., Min Chong, Teik, Yin, Wai-Fong, Chan, Kok-Gan, Chromek, Milan, Brauner, Annelie, Chapman, Matthew R., Beatson, Scott A. and Schembri, Mark A. (2018). Discovery of new genes involved in curli production by a uropathogenic Escherichia coli strain from the highly virulent O45:K1:H7 lineage. mBio, 9 (4) e01462-18. doi: 10.1128/mbio.01462-18

  • The urinary microbiome in patients with refractory urge incontinence and recurrent urinary tract infection

    Chen, Zhuoran, Phan, Minh-Duy, Bates, Lucy J., Peters, Kate M., Mukerjee, Chinmoy, Moore, Kate H. and Schembri, Mark A. (2018). The urinary microbiome in patients with refractory urge incontinence and recurrent urinary tract infection. International Urogynecology Journal, 29 (12), 1-8. doi: 10.1007/s00192-018-3679-2

  • Establishing and validating noninvasive prenatal testing procedure for fetal aneuploidies in Vietnam

    Phan, Minh-Duy, Nguyen, Thong V., Trinh, Huong N. T., Vo, Binh T., Nguyen, Truc M., Nguyen, Nguyen H., Nguyen, Tho T. Q., Do, Thuy T. T., Hoang, Tuyet T. D., Truong, Kiet D., Giang, Hoa and Nguyen, Hoai-Nghia (2018). Establishing and validating noninvasive prenatal testing procedure for fetal aneuploidies in Vietnam. The Journal of Maternal - Fetal & Neonatal Medicine, 32 (23), 1-7. doi: 10.1080/14767058.2018.1481032

  • Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages

    Murthy, Ambika M. V., Phan, Minh-Duy, Peters, Kate M., Nhu, Nguyen Thi Khanh, Welch, Rodney A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2018). Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages. Virulence, 9 (1), 1-32. doi: 10.1080/21505594.2018.1465786

  • Copper ions and coordination complexes as novel carbapenem adjuvants

    Djoko, Karrera Y., Achard, Maud E. S., Phan, Minh-Duy, Lo, Alvin W., Miraula, Manfredi, Prombhul, Sasiprapa, Hancock, Steven J., Peters, Kate M., Sidjabat, Hanna E., Harris, Patrick N., Mitić, Nataša, Walsh, Timothy R., Anderson, Gregory J., Shafer, William M., Paterson, David L., Schenk, Gerhard, McEwan, Alastair G. and Schembri, Mark A. (2018). Copper ions and coordination complexes as novel carbapenem adjuvants. Antimicrobial Agents and Chemotherapy, 62 (2) e02280-17. doi: 10.1128/AAC.02280-17

  • Genome-wide discovery of genes required for capsule production by uropathogenic Escherichia coli

    Goh, Kelvin G. K., Phan, Minh-Duy, Forde, Brian M., Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, Ulett, Glen C., Sweet, Matthew J., Beatson, Scott A. and Schembri, Mark A. (2017). Genome-wide discovery of genes required for capsule production by uropathogenic Escherichia coli. MBio, 8 (5) e01558-17. doi: 10.1128/mBio.01558-17

  • Modifications in the pmrB gene are the primary mechanism for the development of chromosomally encoded resistance to polymyxins in uropathogenic Escherichia coli

    Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Achard, Maud E. S., Forde, Brian M., Hong, Kar Wai, Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, West, Nicholas P., Walker, Mark J., Paterson, David L., Beatson, Scott A. and Schembri, Mark A. (2017). Modifications in the pmrB gene are the primary mechanism for the development of chromosomally encoded resistance to polymyxins in uropathogenic Escherichia coli. Journal of Antimicrobial Chemotherapy, 72 (10), 2729-2736. doi: 10.1093/jac/dkx204

  • Interplay between tolerance mechanisms to copper and acid stress in Escherichia coli

    Djoko, Karrera Y., Phan, Minh-Duy, Peters, Kate M., Walker, Mark J. , Schembri, Mark A. and McEwan, Alastair G. (2017). Interplay between tolerance mechanisms to copper and acid stress in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America, 114 (26), 6818-6823. doi: 10.1073/pnas.1620232114

  • 'Omic' approaches to study Uropathogenic Escherichia coli virulence

    Lo, Alvin W., Moriel, Danilo G., Phan, Minh-Duy, Schulz, Benjamin L., Kidd, Timothy J., Beatson, Scott A. and Schembri, Mark A. (2017). 'Omic' approaches to study Uropathogenic Escherichia coli virulence. Trends in Microbiology, 25 (9), 729-740. doi: 10.1016/j.tim.2017.04.006

  • Novel genes associated with enhanced motility of Escherichia coli ST131

    Kakkanat, Asha, Minh-Duy Phan, Lo, Alvin W., Beatson, Scott A. and Schembri, Mark A. (2017). Novel genes associated with enhanced motility of Escherichia coli ST131. PLoS One, 12 (5) e0176290, e0176290.1-e0176290.22. doi: 10.1371/journal.pone.0176290

  • Identification of IncA/C plasmid replication and maintenance genes and development of a plasmid multi-locus sequence-typing scheme

    Hancock, Steven J., Phan, Minh-Duy, Peters, Kate M., Forde, Brian M., Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, Paterson, David L., Walsh, Timothy R., Beatson, Scott A. and Schembri, Mark A. (2017). Identification of IncA/C plasmid replication and maintenance genes and development of a plasmid multi-locus sequence-typing scheme. Antimicrobial Agents and Chemotherapy, 61 (2) e01740. doi: 10.1128/AAC.01740-16

  • A novel protective vaccine antigen from the core Escherichia coli genome

    Moriel, Danilo G., Tan, Lendl, Goh, Kelvin G. K., Phan, Minh-Duy, Ipe, Deepak S., Lo, Alvin W., Peters, Kate M., Ulett, Glen C., Beatson, Scott. A. and Schembri, Mark A. (2016). A novel protective vaccine antigen from the core Escherichia coli genome. mSphere, 1 (6) e00326-16. doi: 10.1128/mSphere.00326-16

  • The cytochrome bd-I respiratory oxidase augments survival of multidrug-resistant Escherichia coli during infection

    Shepherd, Mark, Achard, Maud E. S., Idris, Adi, Totsika, Makrina, Phan, Minh-Duy, Peters, Kate M., Sarkar, Sohinee, Ribeiro, Cláudia A., Holyoake, Louise V., Ladakis, Dimitrios, Ulett, Glen C., Sweet, Matthew J., Poole, Robert K., McEwan, Alastair G. and Schembri, Mark A. (2016). The cytochrome bd-I respiratory oxidase augments survival of multidrug-resistant Escherichia coli during infection. Scientific Reports, 6 (1) 35285, 35285. doi: 10.1038/srep35285

  • Comprehensive analysis of type 1 fimbriae regulation in fimB-null strains from the multidrug resistant Escherichia coli ST131 clone

    Sarkar, Sohinee, Roberts, Leah W., Phan, Minh-Duy, Tan, Lendl, Lo, Alvin W., Peters, Kate M., Paterson, David L., Upton, Mathew, Ulett, Glen C., Beatson, Scott A., Totsika, Makrina and Schembri, Mark A. (2016). Comprehensive analysis of type 1 fimbriae regulation in fimB-null strains from the multidrug resistant Escherichia coli ST131 clone. Molecular Microbiology, 101 (6), 1069-1087. doi: 10.1111/mmi.13442

  • Effective assembly of fimbriae in Escherichia coli depends on the translocation assembly module nanomachine

    Stubenrauch, Christopher, Belousoff, Matthew J., Hay, Iain D., Shen, Hsin-Hui, Lillington, James, Tuck, Kellie L., Peters, Kate M., Phan, Minh-Duy, Lo, Alvin, W., Schembri, Mark A., Strugnell, Richard A., Waksman, Gabriel and Lithgow, Trevor (2016). Effective assembly of fimbriae in Escherichia coli depends on the translocation assembly module nanomachine. Nature Microbiology, 1 (7) 16064, 16064. doi: 10.1038/nmicrobiol.2016.64

  • Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages

    Kapetanovic, Ronan, Bokil, Nilesh J., Achard, Maud E. S., Ong, Cheryl-lynn Y, Peters, Kate M., Stocks, Claudia J., Phan, Minh-Duy, Monteleone, Mercedes, Schroder, Kate, Irvine, Katharine M., Saunders, Bernadette M., Walker, Mark J., Stacey, Katryn J., McEwan, Alastair G., Schembri, Mark A. and Sweet, Matthew J. (2016). Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages. The FASEB Journal, 30 (5), 1901-1912. doi: 10.1096/fj.201500061

  • Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli.

    Schaale, K., Peters, K. M., Murthy, A. M., Fritzsche, A. K., Phan, M.-D., Totsika, M., Robertson, A. A. B., Nichols, K. B., Cooper, M. A., Stacey, K. J., Ulett, G. C., Schroder, K., Schembri, M. A. and Sweet, M. J. (2016). Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli.. Mucosal Immunology, 9 (1), 124-136. doi: 10.1038/mi.2015.44

  • Lineage-specific methyltransferases define the methylome of the globally disseminated Escherichia coli ST131 clone

    Forde, Brian M., Phan, Minh-Duy, Gawthorne, Jayde A., Ashcroft, Melinda M., Stanton-Cook, Mitchell, Sarkar, Sohinee, Peters, Kate M., Chan, Kok-Gan, Chong, Teik Min, Yin, Wai-Fong, Upton, Mathew, Schembri, Mark A. and Beatson, Scott A. (2015). Lineage-specific methyltransferases define the methylome of the globally disseminated Escherichia coli ST131 clone. MBio, 6 (6) e01602-15, e01602-15. doi: 10.1128/mBio.01602-15

  • The role of H4 flagella in Escherichia coli ST131 virulence

    Kakkanat, Asha, Totsika, Makrina, Schaale, Kolja, Duell, Benjamin L., Lo, Alvin W., Phan, Minh-Duy, Moriel, Danilo G., Beatson, Scott A., Sweet, Matthew J., Ulett, Glen C. and Schembri, Mark A. (2015). The role of H4 flagella in Escherichia coli ST131 virulence. Scientific Reports, 5 (16149) 16149, 1-14. doi: 10.1038/srep16149

  • Conserved features in TamA enable interaction with TamB to drive the activity of the translocation and assembly module.

    Selkrig, Joel, Belousoff, Matthew J., Headey, Stephen J., Heinz, Eva, Shiota, Takuya, Shen, Hsin-Hui, Beckham, Simone A., Bamert, Rebecca S., Phan, Minh-Duy, Schembri, Mark A., Wilce, Matthew C.J., Scanlon, Martin J., Strugnell, Richard A. and Lithgow, Trevor (2015). Conserved features in TamA enable interaction with TamB to drive the activity of the translocation and assembly module.. Scientific Reports, 5 (1) 12905, 12905. doi: 10.1038/srep12905

  • Molecular analysis of asymptomatic bacteriuria Escherichia coli strain VR50 reveals adaptation to the urinary tract by gene acquisition

    Beatson, Scott A., Ben Zakour, Nouri L., Totsika, Makrina, Forde, Brian M., Watts, Rebecca E., Mabbett, Amanda N., Szubert, Jan M., Sarkar, Sohinee, Phan, Minh-Duy, Peters, Kate M., Petty, Nicola K., Alikhan, Nabil-Fareed, Sullivan, Mitchell J., Gawthorne, Jayde A., Stanton-Cook, Mitchell, Nguyen Thi Khanh Nhu, Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, Hancock, Viktoria, Ussery, David W., Ulett, Glen C. and Schembri, Mark A. (2015). Molecular analysis of asymptomatic bacteriuria Escherichia coli strain VR50 reveals adaptation to the urinary tract by gene acquisition. Infection and Immunity, 83 (5), 1749-1764. doi: 10.1128/IAI.02810-14

  • Molecular Characterization of a Multidrug Resistance IncF Plasmid from the Globally Disseminated Escherichia coli ST131 Clone.

    Phan, Minh Duy, Forde, Brian M., Peters, Kate M., Sarkar, Sohinee, Hancock, Steven, Stanton-Cook, Mitchell, Zakour, Nouri L. Ben, Upton, Mathew, Beatson, Scott A. and Schembri, Mark A. (2015). Molecular Characterization of a Multidrug Resistance IncF Plasmid from the Globally Disseminated Escherichia coli ST131 Clone.. PLoS One, 10 (4) e0122369, e0122369-e0122369. doi: 10.1371/journal.pone.0122369

  • Third-generation cephalosporin resistance conferred by a chromosomally encoded blaCMY-23 gene in the Escherichia coli ST131 reference strain EC958

    Phan, Minh-Duy, Peters, Kate M., Sarkar, Sohinee, Forde, Brian M., Lo, Alvin W., Stanton-Cook, Mitchell, Roberts, Leah W., Upton, Mathew, Beatson, Scott A. and Schembri, Mark A. (2015). Third-generation cephalosporin resistance conferred by a chromosomally encoded blaCMY-23 gene in the Escherichia coli ST131 reference strain EC958. Journal of Antimicrobial Chemotherapy, 70 (7) dkv066, 1969-1972. doi: 10.1093/jac/dkv066

  • The intimin-like protein FdeC is regulated by H-NS and temperature in Enterohaemorrhagic Escherichia coli

    Easton, Donna M., Allsopp, Luke P., Phan, Minh-Duy, Gomes Moriel, Danilo, Goh, Guan Kai, Beatson, Scott A., Mahony, Timothy J., Cobbold, Rowland N. and Schembri, Mark A. (2014). The intimin-like protein FdeC is regulated by H-NS and temperature in Enterohaemorrhagic Escherichia coli. Applied and Environmental Microbiology, 80 (23), 7337-7347. doi: 10.1128/AEM.02114-14

  • The complete genome sequence of Escherichia coli EC958: a high quality reference sequence for the globally disseminated multidrug resistant E. coli O25b:H4-ST131 clone

    Forde, Brian M., Ben Zakour, Nouri L., Stanton-Cook, Mitchell, Phan, Minh-Duy, Totsika, Makrina, Peters, Kate M., Chan, Kok Gan, Schembri, Mark A., Upton, Mathew and Beatson, Scott A. (2014). The complete genome sequence of Escherichia coli EC958: a high quality reference sequence for the globally disseminated multidrug resistant E. coli O25b:H4-ST131 clone. PLoS One, 9 (8) e104400, e104400.1-e104400.13. doi: 10.1371/journal.pone.0104400

  • Global dissemination of a multidrug resistant Escherichia coli clone

    Petty, Nicola K., Ben Zakour, Nouri L., Stanton-Cook, Mitchell, Skippington, Elizabeth, Totsika, Makrina, Forde, Brian M., Phan, Minh-Duy, Gomes Moriel, Danilo, Peters, Kate M., Davies, Mark, Rogers, Benjamin A., Dougan, Gordon, Rodriguez-Baño, Jesús, Pascual, Alvaro, Pitout, Johann D., Upton, Mathew, Paterson, David L., Walsh, Timothy R., Schembri, Mark A. and Beatson, Scott A. (2014). Global dissemination of a multidrug resistant Escherichia coli clone. Proceedings of the National Academy of Sciences, 111 (15), 5694-5699. doi: 10.1073/pnas.1322678111

  • Role of capsule and O antigen in the virulence of uropathogenic Escherichia coli

    Sarkar, Sohinee, Ulett, Glen C., Totsika, Makrina, Phan, Minh-Duy and Schembri, Mark A. (2014). Role of capsule and O antigen in the virulence of uropathogenic Escherichia coli. PLoS One, 9 (4) e94786, e94786. doi: 10.1371/journal.pone.0094786

  • Molecular analysis of the Acinetobacter baumannii biofilm-associated protein

    Goh, H. M. Sharon, Beatson, Scott A., Totsika, Makrina, Moriel, Danilo G., Phan, Minh-Duy, Szubert, Jan, Runnegar, Naomi, Sidjabat, Hanna E., Paterson, David L., Nimmo, Graeme R., Lipman, Jeffrey and Schembri, Mark A. (2013). Molecular analysis of the Acinetobacter baumannii biofilm-associated protein. Applied and Environmental Microbiology, 79 (21), 6535-6543. doi: 10.1128/AEM.01402-13

  • The serum resistome of a globally disseminated multidrug resistant uropathogenic Escherichia coli clone

    Phan, Minh-Duy, Peters, Kate M., Sarkar, Sohinee, Lukowski, Samuel W., Allsopp, Luke P., Moriel, Danilo Gomes, Achard, Maud E. S., Totsika, Makrina, Marshall, Vikki M., Upton, Mathew, Beatson, Scott A. and Schembri, Mark A. (2013). The serum resistome of a globally disseminated multidrug resistant uropathogenic Escherichia coli clone. PloS Genetics, 9 (10) e1003834, e1003834.1-e1003834.18. doi: 10.1371/journal.pgen.1003834

  • A comparison of dense transposon insertion libraries in the Salmonella serovars Typhi and Typhimurium

    Barquist, Lars, Langridge, Gemma C., Turner, Daniel J., Phan, Minh-Duy, Turner, A. Keith, Bateman, Alex, Parkhill, Julian, Wain, John and Gardner, Paul P. (2013). A comparison of dense transposon insertion libraries in the Salmonella serovars Typhi and Typhimurium. Nucleic Acids Research, 41 (8), 4549-4564. doi: 10.1093/nar/gkt148

  • Uropathogenic Escherichia coli mediated urinary tract infection

    Totsika, Makrina, Moriel, Danilo Gomes, Idris, Adi, Rogers, Benjamin A., Wurpel, Daniel J., Phan, Minh-Duy, Paterson, David L. and Schembri, Mark A. (2012). Uropathogenic Escherichia coli mediated urinary tract infection. Current Drug Targets, 13 (11), 1386-1399. doi: 10.2174/138945012803530206

  • Identification of genes important for growth of asymptomatic Bacteriuria Escherichia coli in urine

    Vejborg, Rebecca M., de Evgrafov, Mari R., Phan, Minh Duy, Totsika, Makrina, Schembri, Mark A. and Hancock, Viktoria (2012). Identification of genes important for growth of asymptomatic Bacteriuria Escherichia coli in urine. Infection and Immunity, 80 (9), 3179-3188. doi: 10.1128/IAI.00473-12

  • Discovery of an archetypal protein transport system in bacterial outer membranes

    Selkrig, Joel, Mosbahi, Khedidja, Webb, Chaille T., Belousoff, Matthew J., Perry, Andrew J., Wells, Timothy J., Morris, Faye, Leyton, Denisse L., Totsika, Makrina, Phan, Minh-Duy, Celik, Nermin, Kelly, Michelle, Oates, Clare, Hartland, Elizabeth L., Robins-Browne, Roy M., Ramarathinam, Sri Harsha, Purcell, Anthony W., Schembri, Mark A., Strugnell, Richard A., Henderson, Ian R., Walker, Daniel and Lithgow, Trevor (2012). Discovery of an archetypal protein transport system in bacterial outer membranes. Nature Structural and Molecular Biology, 19 (5), 506-510. doi: 10.1038/nsmb.2261

  • Insights into a multidrug resistant escherichia coli pathogen of the globally disseminated ST131 lineage: Genome analysis and virulence mechanisms

    Totsika, Makrina, Beatson, Scott A., Sarkar, Sohinee, Phan, Minh-Duy, Petty, Nicola K., Bachmann, Nathan, Szubert, Marek, Sidjabat, Hanna E., Paterson, David L., Upton, Mathew and Schembri, Mark A. (2011). Insights into a multidrug resistant escherichia coli pathogen of the globally disseminated ST131 lineage: Genome analysis and virulence mechanisms. Plos One, 6 (10) e26578, e26578-1-e26578-11. doi: 10.1371/journal.pone.0026578

  • Emergence of a globally dominant IncHI1 plasmid type associated with multiple drug resistant typhoid

    Holt, Kathryn E., Phan, Minh Duy, Baker, Stephen, Duy, Pham Thanh, Nga, Tran Vu Thieu, Nair, Satheesh, Turner, A. Keith, Walsh, Ciara, Fanning, Se´amus, Farrell-Ward, Sine´ad, Dutta, Shanta, Kariuki, Sam, Weill, Francois-Xavier, Parkhill, Julian, Dougan, Gordon and Wain, John (2011). Emergence of a globally dominant IncHI1 plasmid type associated with multiple drug resistant typhoid. PLoS Neglected Tropical Diseases, 5 (7) e1245, e1245-1-e1245-13. doi: 10.1371/journal.pntd.0001245

  • Characterization of EhaJ, a new autotransporter protein from enterohemorrhagic and enteropathogenic Escherichia coli

    Easton, Donna M., Totsika, Makrina, Allsopp, Luke P., Phan, Minh-Duy, Idris, Adi, Wurpel, Daniël J., Sherlock, Orla, Zhang, Bing, Venturini, Carola, Beatson, Scott A., Mahony, Timothy J., Cobbold, Rowland N. and Schembri, Mark A. (2011). Characterization of EhaJ, a new autotransporter protein from enterohemorrhagic and enteropathogenic Escherichia coli. Frontiers in Microbiology: Frontiers in Cellular and Infection Microbiology, 2 (JUNE), 120.1-120.9. doi: 10.3389/fmicb.2011.00120

  • Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants

    Langridge, Gemma C., Phan, Minh-Duy, Turner, Daniel J., Perkins, Timothy T., Parts, Leopold, Haase, Jana, Charles, Ian, Maskell, Duncan J., Peters, Sarah E., Dougan, Gordon, Wain, John, Parkhill, Julian and Turner, A. Keith (2009). Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants. Genome Research, 19 (12), 2308-2316. doi: 10.1101/gr.097097.109

  • Variation in Salmonella enterica serovar Typhi IncHI1 plasmids during the global spread of resistant typhoid fever

    Phan, Minh-Duy, Kidgell, Claire, Nair, Satheesh, Holt, Kathryn E., Turner, Arthur K., Hinds, Jason, Butcher, Philip, Cooke, Fiona J., Thomson, Nicholas R., Titball, Richard, Bhutta, Zulfiqar A., Hassan, Rumina, Dougan, Gordon and Wain, John (2009). Variation in Salmonella enterica serovar Typhi IncHI1 plasmids during the global spread of resistant typhoid fever. Antimicrobial Agents and Chemotherapy, 53 (2), 716-727. doi: 10.1128/AAC.00645-08

  • Comparison of MAS-PCR and GenoType MTBDR assay for the detection of rifampicin-resistant Mycobacterium tuberculosis

    Tho, D. Q., Ha, D. T. M., Duy, P. M., Lan, N. T. N., Hoa, D. V., Chau, N. V. V., Farrar, J. and Caws, M. (2008). Comparison of MAS-PCR and GenoType MTBDR assay for the detection of rifampicin-resistant Mycobacterium tuberculosis. International Journal of Tuberculosis And Lung Disease, 12 (11), 1306-1312.

  • IncHI plasmids, a dynamic link between resistance and pathogenicity

    Phan, Minh-Duy and Wain, John (2008). IncHI plasmids, a dynamic link between resistance and pathogenicity. Journal of Infection in Developing Countries, 2 (4), 272-278. doi: 10.3855/jidc.221

  • Fluoroquinolone resistance detection in Mycobacterium tuberculosis with locked nucleic acid probe real-time PCR

    van Doorn, H. R., An, D. D., de Jong, M. D., Lan, N. T., Hoa, D. V., Quy, H. T., Chau, N. V., Duy, P. M., Tho, D. Q., Chinh, N. T., Farrar, J. J. and Caws, M. (2008). Fluoroquinolone resistance detection in Mycobacterium tuberculosis with locked nucleic acid probe real-time PCR. International Journal of Tuberculosis and Lung Disease, 12 (7), 736-742.

  • Fluoroquinolone resistance detection in Mycobacterium tuberculosis with locked nucleic acid probe real-time PCR

    van Doorn, H. R., An, D. D., de Jong, M. D., Lan, N. T. N., Hoa, D. V., Quy, H. T., Chau, N. V. V., Duy, P. M., Tho, D. Q., Chinh, N. T., Farrar, J J and Caws, M. (2008). Fluoroquinolone resistance detection in Mycobacterium tuberculosis with locked nucleic acid probe real-time PCR. International Journal of Tuberculosis and Lung Disease, 12 (7), 736-742.

  • The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis

    Caws, Maxine, Thwaites, Guy, Dunstan, Sarah, Hawn, Thomas R., Lan, Nguyen Thi, Thuong, Nguyen Thuy, Stepniewska, Kasia, Huyen, Mai Nguyet, Bang, Nguyen Duc, Loc, Tran Huy, Gagneux, Sebastien, van Soolingen, Dick, Kremer, Kristin, van der Sande, Marianne, Small, Peter, Anh, Phan Thi, Chinh, Nguyen Tran, Quy, Hoang Thi, Duyen, Nguyen Thi, Tho, Dao Quang, Hieu, Nguyen T., Torok, Estee, Hien, Tranh Tinh, Dung, Nguyen Huy, Nhu, Nguyen T., Phan, Minh Duy, van Vinh Chau, Nguyen and Farrar, Jeremy (2008). The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis. PLoS Pathogens, 4 (3) e1000034, e1000034-1-e1000034-9. doi: 10.1371/journal.ppat.1000034

  • Relationship between Mycobacterium tuberculosis genotype and the clinical phenotype of pulmonary and meningeal tuberculosis

    Thwaites, Guy, Caws, Maxine, Chau, Tran Thi, D'Sa, Anthony, Lan, Nguyen Thi Guoc, Huyen, Mai Nguyet Thu, Gagneux, Sebastian, Anh, Phan Thi Hoanh Anh, Tho, Dau Quang, Torok, Estee, Nhu, Nguyen Thi Qyunh, Duyen, Nguyen Thi Hong, Duy, Phan Minh, Richenberg, Jonathan, Simmons, Cameron, Hien, Tran Tinh and Farrar, Jeremy (2008). Relationship between Mycobacterium tuberculosis genotype and the clinical phenotype of pulmonary and meningeal tuberculosis. Journal of Clinical Microbiology, 46 (4), 1363-1368. doi: 10.1128/JCM.02180-07

  • Multidrug-resistant Salmonella enterica serovar paratyphi A harbors IncHI1 plasmids similar to those found in serovar typhi

    Holt, Kathryn E., Thomson, Nicholas R., Wain, John, Phan, Minh Duy, Nair, Satheesh, Hasan, Rumina, Bhutta, Zulfiqar A., Quail, Michael A., Norbertczak, Halina, Walker, Danielle, Dougan, Gordon and Parkhill, Julian (2007). Multidrug-resistant Salmonella enterica serovar paratyphi A harbors IncHI1 plasmids similar to those found in serovar typhi. Journal of Bacteriology, 189 (11), 4257-4264. doi: 10.1128/JB.00232-07

  • PCR-restriction fragment length polymorphism for rapid, low-cost identification of isoniazid-resistant Mycobacterium tuberculosis

    Caws, Maxine, Tho, Dau Quang, Duy, Phan Minh, Lan, Nguyen Thi Ngoc, Hoa, Dai Viet, Torok, Mili Estee, Chau, Tran Thi Hong, Chau, Nguyen Van Vinh, Chinh, Nguyen Tran and Farrar, Jeremy (2007). PCR-restriction fragment length polymorphism for rapid, low-cost identification of isoniazid-resistant Mycobacterium tuberculosis. Journal of Clinical Microbiology, 45 (6), 1789-1793. doi: 10.1128/JCM.01960-06

  • Molecular analysis of Mycobacterium tuberculosis causing multidrug-resistant tuberculosis meningitis

    Caws, M., Thwaites, G. E., Duy, P. M., Tho, D. Q., Lan, N. T., Hoa, D. V., Chau, T. T., Huyen, M. N., Anh, P. T., Chau, N. V., Chinh, T. N., Stepniewska, K. and Farrar, J. (2007). Molecular analysis of Mycobacterium tuberculosis causing multidrug-resistant tuberculosis meningitis. International Journal of Tuberculosis and Lung Disease, 11 (2), 202-208.

  • Beijing genotype of Mycobacterium tuberculosis is significantly associated with human immunodeficiency virus infection and multidrug resistance in cases of tuberculous meningitis

    Caws, Maxine, Thwaites, Guy, Stepniewska, Kasia, Nguyen, Thi Ngoc Lan, Nguyen, Thi Hong Duyen, Nguyen, Thi Phuong, Mai, Nguyet Thu Huyen, Phan, Minh Duy, Tran, Huu Loc, Tran, Thi Hong Chau, van Soolingen, Dick, Kremer, Kristin, Nguyen, Van Vinh Chau, Nguyen, Tran Chinh and Farrar, Jeremy (2006). Beijing genotype of Mycobacterium tuberculosis is significantly associated with human immunodeficiency virus infection and multidrug resistance in cases of tuberculous meningitis. Journal of Clinical Microbiology, 44 (11), 3934-3939. doi: 10.1128/JCM.01181-06

  • Mutations prevalent among rifampin- and isoniazid-resistant Mycobacterium tuberculosis isolates from a hospital in Vietnam

    Caws, M., Duy, Phan Minh, Tho, Dau Quang, Lan, Nguyen Thi Ngoc, Hoa, Dai Viet and Farrar, Jeremy (2006). Mutations prevalent among rifampin- and isoniazid-resistant Mycobacterium tuberculosis isolates from a hospital in Vietnam. Journal of Clinical Microbiology, 44 (7), 2333-2337. doi: 10.1128/JCM.00330-06

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