The University of Queensland

Multifaceted roles of retromer in EGFR trafficking and signaling activation

Yang, Zhe, Feng, Zhengyang, Li, Zebin and Teasdale, Rohan D. (2022). Multifaceted roles of retromer in EGFR trafficking and signaling activation. Cells, 11 (21) 3358, 1-17. doi: 10.3390/cells11213358

De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex

Chen, Kai-En, Guo, Qian, Hill, Timothy A., Cui, Yi, Kendall, Amy K., Yang, Zhe, Hall, Ryan J., Healy, Michael D., Sacharz, Joanna, Norwood, Suzanne J., Fonseka, Sachini, Xie, Boyang, Reid, Robert C., Leneva, Natalya, Parton, Robert G., Ghai, Rajesh, Stroud, David A., Fairlie, David P, Suga, Hiroaki, Jackson, Lauren P., Teasdale, Rohan D., Passioura, Toby and Collins, Brett M. (2021). De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex. Science Advances, 7 (49) eabg4007, eabg4007. doi: 10.1126/sciadv.abg4007

Retromer dependent changes in cellular homeostasis and Parkinson’s disease

Yang, Zhe, Li, Zebin and Teasdale, Rohan D. (2021). Retromer dependent changes in cellular homeostasis and Parkinson’s disease. Essays in Biochemistry, 65 (7), 987-998. doi: 10.1042/ebc20210023

Formation of retromer transport carriers is disrupted by the Parkinson disease‐linked Vps35 D620N variant

Cui, Yi, Yang, Zhe, Flores‐Rodriguez, Neftali, Follett, Jordan, Ariotti, Nicholas, Wall, Adam A., Parton, Robert G. and Teasdale, Rohan D. (2021). Formation of retromer transport carriers is disrupted by the Parkinson disease‐linked Vps35 D620N variant. Traffic, 22 (4) tra.12779, 123-136. doi: 10.1111/tra.12779

Subcellular fractionation of HeLa cells for lysosome enrichment using a continuous Percoll-density gradient

Carosi, Julian M., Hattersley, Kathryn J., Cui, Yi, Yang, Zhe, Teasdale, Rohan D. and Sargeant, Timothy J. (2019). Subcellular fractionation of HeLa cells for lysosome enrichment using a continuous Percoll-density gradient. Bio-Protocol, 9 (18) e3362, e3362. doi: 10.21769/BioProtoc.3362

Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities

Chandra, Mintu, Chin, Yanni K.-Y., Mas, Caroline, Feathers, J. Ryan, Paul, Blessy, Datta, Sanchari, Chen, Kai-En, Jia, Xinying, Yang, Zhe, Norwood, Suzanne J., Mohanty, Biswaranjan, Bugarcic, Andrea, Teasdale, Rohan D., Henne, W. Mike, Mobli, Mehdi and Collins, Brett M. (2019). Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities. Nature Communications, 10 (1) 1528, 1528. doi: 10.1038/s41467-019-09355-y

A role of GCC88 in the retrograde transport of CI-M6PR and the maintenance of lysosomal activity

Cui, Yi, Yang, Zhe and Teasdale, Rohan D. (2019). A role of GCC88 in the retrograde transport of CI-M6PR and the maintenance of lysosomal activity. Cell Biology International, 43 (11) cbin.11118, 1234-1244. doi: 10.1002/cbin.11118

Retromer has a selective function in cargo sorting via endosome transport carriers

Cui, Yi, Carosi, Julian M., Yang, Zhe, Ariotti, Nicholas, Kerr, Markus C., Parton, Robert G., Sargeant, Timothy J. and Teasdale, Rohan D. (2018). Retromer has a selective function in cargo sorting via endosome transport carriers. The Journal of Cell Biology, 218 (2), jcb.201806153-631. doi: 10.1083/jcb.201806153

Sorting Nexin 27 (SNX27) regulates the trafficking and activity of the glutamine transporter ASCT2

Yang, Zhe, Follett, Jordan, Kerr, Markus C., Clairfeuille, Thomas, Chandra, Mintu, Collins, Brett M. and Teasdale, Rohan D. (2018). Sorting Nexin 27 (SNX27) regulates the trafficking and activity of the glutamine transporter ASCT2. Journal of Biological Chemistry, 293 (18), 6802-6811. doi: 10.1074/jbc.RA117.000735

The functional roles of retromer in Parkinson's disease

Cui, Yi, Yang, Zhe and Teasdale, Rohan D. (2017). The functional roles of retromer in Parkinson's disease. FEBS Letters, 592 (7), 1096-1112. doi: 10.1002/1873-3468.12931

SopB-mediated recruitment of SNX18 facilitates Salmonella typhimurium internalization by the host cell

Liebl, David, Qi, Xiaying, Zhe, Yang, Barnett, Timothy C. and Teasdale, Rohan D. (2017). SopB-mediated recruitment of SNX18 facilitates Salmonella typhimurium internalization by the host cell. Frontiers in Cellular and Infection Microbiology, 7 (JUN) 257. doi: 10.3389/fcimb.2017.00257

Collagen beta (1-O) galactosyltransferase 1 (GLT25D1) is required for the secretion of high molecular weight adiponectin and affects lipid accumulation

Webster, Julie A., Yang, Zhe, Kim, Yu-Hee, Loo, Dorothy, Mosa, Rasha M., Li, Hongzhuo and Chen, Chen (2017). Collagen beta (1-O) galactosyltransferase 1 (GLT25D1) is required for the secretion of high molecular weight adiponectin and affects lipid accumulation. Bioscience Reports, 37 (3) BSR20170105, BSR20170105. doi: 10.1042/BSR20170105

Salmonella effector SopD2 interferes with Rab34 function

Teo, Wei Xuan, Yang, Zhe, Kerr, Markus Charles, Luo, Lin, Guo, Zhong, Alexandrov, Kirill, Stow, Jenny Lea and Teasdale, Rohan David (2017). Salmonella effector SopD2 interferes with Rab34 function. Cell Biology International, 41 (4), 433-446. doi: 10.1002/cbin.10739

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

Clairfeuille, Thomas, Mas, Caroline, Chan, Audrey S. M., Yang, Zhe, Tello-Lafoz, Maria, Chandra, Mintu, Wigagdo, Jocelyn, Kerr, Markus, Blessy, Paul, Merida, Isabel, Teasdale, Rohan D., Pavlos, Nathan J., Anggono, Victor and Collins, Brett (2016). A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex. Nature Structural and Molecular Biology, 23 (10), 921-932. doi: 10.1038/nsmb.3290

Parkinson disease-linked Vps35 R524W mutation impairs the endosomal association of retromer and induces α-synuclein aggregation

Follett, Jordan, Bugarcic, Andrea, Yang, Zhe, Ariotti, Nicholas, Norwood, Suzanne J., Collins, Brett M., Parton, Robert G. and Teasdale, Rohan D. (2016). Parkinson disease-linked Vps35 R524W mutation impairs the endosomal association of retromer and induces α-synuclein aggregation. Journal of Biological Chemistry, 291 (35), 18283-18298. doi: 10.1074/jbc.M115.703157

Functional characterization of retromer in GLUT4 storage vesicle formation and adipocyte differentiation

Yang, Zhe, Hong, Lee Kian, Follett, Jordan, Wabitsch, Martin, Hamilton, Nicholas A., Collins, Brett, Bugarcic, Andrea and Teasdale, Rohan D. (2016). Functional characterization of retromer in GLUT4 storage vesicle formation and adipocyte differentiation. The FASEB Journal, 39 (3), 1037-1050. doi: 10.1096/fj.15-274704

SseK3 is a salmonella effector that binds trim32 and modulates the host's nf-kappa b signalling activity

Yang, Zhe, Soderholm, Amelia, Lung, Tania Wong Fok, Giogha, Cristina, Hill, Michelle M., Brown, Nathaniel F., Hartland, Elizabeth and Teasdale, Rohan D. (2015). SseK3 is a salmonella effector that binds trim32 and modulates the host's nf-kappa b signalling activity. PL o S One, 10 (9) e0138529, 1-20. doi: 10.1371/journal.pone.0138529

Phosphoinositide binding by the SNX27 FERM domain regulates localisation at the immune synapse of activated T-cells

Ghai, Rajesh, Tello-Lafoz, Maria, Norwood, Suzanne J., Yang, Zhe, Clairefeuille, Thomas, Teasdale, Rohan D., Mérida, Isabel and Collins, Brett M. (2015). Phosphoinositide binding by the SNX27 FERM domain regulates localisation at the immune synapse of activated T-cells. Journal of Cell Science, 128 (3), 553-565. doi: 10.1242/jcs.158204

The Vps35 D620N mutation linked to Parkinson's disease disrupts the cargo sorting function of retromer

Follett, Jordan, Norwood, Suzanne J., Hamilton, Nicholas A., Mohan, Megha, Kovtun, Oleksiy, Tay, Stephanie, Yang, Zhe, Wood, Stephen A., Mellick, George D., Silburn, Peter A., Collins, Brett M., Bugarcic, Andrea and Teasdale, Rohan D. (2014). The Vps35 D620N mutation linked to Parkinson's disease disrupts the cargo sorting function of retromer. Traffic, 15 (2), 230-244. doi: 10.1111/tra.12136

A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens

Verma, Suzie, Han, Siew Ping, Michael, Magdalene, Gomez, Guillermo, Yang, Zhe, Teasdale, Rohan D., Ratheesh, Aparna, Kovacs, Eva M., Ali, Radiya G. and Yap, Alpha S.K. (2012). A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens. Molecular Biology of The Cell, 23 (23), 4601-4610. doi: 10.1091/mbc.E12-08-0574

VPS26A and VPS26B subunits define distinct Retromer complexes

Bugarcic, Andrea, Yang, Zhe, Kerr, Markus C., Griffith, John Griffin, Collins, Brett M. and Teasdale, Rohan D. (2011). VPS26A and VPS26B subunits define distinct Retromer complexes. Traffic, 12 (12), 1759-1773. doi: 10.1111/j.1600-0854.2011.01284.x

Parkinson-associated VPS35 mutations alter retromer cellular functions

Teasdale, R., Follett, J., Bugarcic, A., Yang, Z. and Collins, B. (2015). Parkinson-associated VPS35 mutations alter retromer cellular functions. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia Conference, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13185

MOLECULAR CO-ORDINATION ON INSULIN RECEPTOR SUBSTRATE-1 (IRS-1)

Zhe Yang (2011). MOLECULAR CO-ORDINATION ON INSULIN RECEPTOR SUBSTRATE-1 (IRS-1). PhD Thesis, Diamantina Institute for Cancer, Immunology and Metabolic Medicine, The University of Queensland.