The University of Queensland

RNA Interference

Brosnan, C.A., McCallum,E.J., Botella, J.R. and Carroll, B.J. (2008). RNA Interference. The Handbook of Plant Functional Genomics: Concepts and Protocols. (pp. 209-225) edited by Kahl, G. and Meksem, K.. Germany: Wiley - Blackwell. doi: 10.1002/9783527622542.ch10

In planta dynamics, transport‐biases, and endogenous functions of mobile siRNAs in Arabidopsis

Devers, Emanuel A., Brosnan, Christopher A., Sarazin, Alexis, Schott, Gregory, Lim, Peiqi, Lehesranta, Satu, Helariutta, Yrjö and Voinnet, Olivier (2023). In planta dynamics, transport‐biases, and endogenous functions of mobile siRNAs in Arabidopsis. The Plant Journal, 115 (5), 1377-1393. doi: 10.1111/tpj.16327

ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription

Dai, Chuan-Yang, Ng, Chai Chee, Hung, Grace Ching Ching, Kirmes, Ina, Hughes, Laetitia A., Du, Yunguang, Brosnan, Christopher A., Ahier, Arnaud, Hahn, Anne, Haynes, Cole M., Rackham, Oliver, Filipovska, Aleksandra and Zuryn, Steven (2023). ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription. Nature Cell Biology, 25 (8), 1-10. doi: 10.1038/s41556-023-01192-y

Perspectives on plant virus diseases in a climate change scenario of elevated temperatures

Tsai, Wei-An, Brosnan, Christopher A., Mitter, Neena and Dietzgen, Ralf G. (2022). Perspectives on plant virus diseases in a climate change scenario of elevated temperatures. Stress Biology, 2 (1) 37, 1-26. doi: 10.1007/s44154-022-00058-x

RNAi as a foliar spray: efficiency and challenges to field applications

Hoang, Bao Tram L., Fletcher, Stephen J., Brosnan, Christopher A., Ghodke, Amol B., Manzie, Narelle and Mitter, Neena (2022). RNAi as a foliar spray: efficiency and challenges to field applications. International Journal of Molecular Sciences, 23 (12) 6639. doi: 10.3390/ijms23126639

Foliar application of clay-delivered RNA interference for whitefly control

Jain, Ritesh G, Fletcher, Stephen J, Manzie, Narelle, Robinson, Karl E, Li, Peng, Lu, Elvin, Brosnan, Christopher A, Xu, Zhi Ping and Mitter, Neena (2022). Foliar application of clay-delivered RNA interference for whitefly control. Nature Plants, 8 (5), 535-548. doi: 10.1038/s41477-022-01152-8

miRNA communication on another level

Brosnan, Christopher A. and Mitter, Neena (2021). miRNA communication on another level. Nature Plants, 7 (10), 1328-1329. doi: 10.1038/s41477-021-01006-9

Mitochondrial mistranslation modulated by metabolic stress causes cardiovascular disease and reduced lifespan

Richman, Tara R., Ermer, Judith A., Siira, Stefan J., Kuznetsova, Irina, Brosnan, Christopher A., Rossetti, Giulia, Baker, Jessica, Perks, Kara L., Cserne Szappanos, Henrietta, Viola, Helena M., Gray, Nicola, Larance, Mark, Hool, Livia C., Zuryn, Steven, Rackham, Oliver and Filipovska, Aleksandra (2021). Mitochondrial mistranslation modulated by metabolic stress causes cardiovascular disease and reduced lifespan. Aging Cell, 20 (7) e13408, e13408. doi: 10.1111/acel.13408

Defective embryo and meristems genes are required for cell division and gamete viability in Arabidopsis

Lee, Chin Hong, Hawker, Nathaniel P., Peters, Jonathan R., Lonhienne, Thierry G. A., Gursanscky, Nial R., Matthew, Louisa, Brosnan, Christopher A., Mann, Christopher W. G., Cromer, Laurence, Taochy, Christelle, Ngo, Quy A., Sundaresan, Venkatesan, Schenk, Peer M., Kobe, Bostjan, Borges, Filipe, Mercier, Raphael, Bowman, John L. and Carroll, Bernard J. (2021). Defective embryo and meristems genes are required for cell division and gamete viability in Arabidopsis. PL o S Genetics, 17 (5) e1009561, 1-31. doi: 10.1371/journal.pgen.1009561

Cell-type-specific profiling of loaded miRNAs from Caenorhabditis elegans reveals spatial and temporal flexibility in Argonaute loading

Brosnan, Christopher A., Palmer, Alexander J. and Zuryn, Steven (2021). Cell-type-specific profiling of loaded miRNAs from Caenorhabditis elegans reveals spatial and temporal flexibility in Argonaute loading. Nature Communications, 12 (1) 2194, 1-16. doi: 10.1038/s41467-021-22503-7

Nuclear RNA purification by flow cytometry to study nuclear processes in plants

Moro, Belén, Kisielow, Malgorzata, Borrero, Veronica Barragan, Bouet, Antoine, Brosnan, Christopher A. and Bologna, Nicolás G. (2021). Nuclear RNA purification by flow cytometry to study nuclear processes in plants. STAR Protocols, 2 (1) 100320, 100320. doi: 10.1016/j.xpro.2021.100320

Movement and differential consumption of short interfering RNA duplexes underlie mobile RNA interference

Devers, Emanuel A., Brosnan, Christopher A., Sarazin, Alexis, Albertini, Daniele, Amsler, Andrea C., Brioudes, Florian, Jullien, Pauline E., Lim, Peiqi, Schott, Gregory and Voinnet, Olivier (2020). Movement and differential consumption of short interfering RNA duplexes underlie mobile RNA interference. Nature Plants, 6 (7), 789-799. doi: 10.1038/s41477-020-0687-2

Genome-scale, single-cell-type resolution of microRNA activities within a whole plant organ

Brosnan, Christopher Andrew, Sarazin, Alexis, Lim, PeiQi, Bologna, Nicolas Gerardo, Hirsch-Hoffmann, Matthias and Voinnet, Olivier (2019). Genome-scale, single-cell-type resolution of microRNA activities within a whole plant organ. EMBO Journal, 38 (13) e100754, e100754. doi: 10.15252/embj.2018100754

Structural flexibility enables alternative maturation, ARGONAUTE sorting and activities of miR168, a global gene silencing regulator in plants

Iki, Taichiro, Clery, Antoine, Bologna, Nicolas G., Sarazin, Alexis, Brosnan, Christopher A., Pumplin, Nathan, Allain, Frederic H. T. and Voinnet, Olivier (2018). Structural flexibility enables alternative maturation, ARGONAUTE sorting and activities of miR168, a global gene silencing regulator in plants. Molecular Plant, 11 (8), 1008-1023. doi: 10.1016/j.molp.2018.05.006

A complex of Arabidopsis DRB proteins can impair dsRNA processing

Tschopp, Marie-Aude, Iki, Taichiro, Brosnan, Christopher A., Jullien, Pauline E. and Pumplin, Nathan (2017). A complex of Arabidopsis DRB proteins can impair dsRNA processing. RNA, 23 (5), 782-797. doi: 10.1261/rna.059519.116

RNA decay and RNA silencing in plants: Competition or collaboration?

Christie, Michael, Brosnan, Christopher A., Rothnagel, Joseph A. and Carroll, Bernard J. (2011). RNA decay and RNA silencing in plants: Competition or collaboration?. Frontiers in Plant Science, 2 (DEC) 99, 99.1-99.7. doi: 10.3389/fpls.2011.00099

Cell-to-cell and long-distance siRNA movement in plants: Mechanisms and biological implications

Brosnan, Christopher Andrew and Voinnet, Olivier (2011) Cell-to-cell and long-distance siRNA movement in plants: Mechanisms and biological implications. Current Opinion in Plant Biology, 14 5: 580-587. doi:10.1016/j.pbi.2011.07.011

The long and the short of noncoding RNAs

Brosnan, Christopher A. and Voinnet, Olivier (2009) The long and the short of noncoding RNAs. Current Opinion in Cell Biology, 21 3: 416-425. doi:10.1016/j.ceb.2009.04.001

Nuclear gene silencing directs reception of long-distance mRNA silencing in Arabidopsis

Brosnan, C., Mitter, N., Christie, M., Smith, N., Waterhouse, P. and Carroll, B. (2007). Nuclear gene silencing directs reception of long-distance mRNA silencing in Arabidopsis. Proceedings of The National Academy of Sciences of The United States of America, 104 (37), 14741-14746. doi: 10.1073/pnas.0706701104

RNA interference-inducing hairpin RNAs in plants act through the viral defence pathway

Fusaro, Adriana F., Matthew, Louisa, Smith, Neil A., Curtin, Shaun J., Dedic-Hagan, Jasmina, Ellacott, Geoff A., Watson, John M., Wang, Ming-Bo, Brosnan, Chris, Carroll, Bernard J. and Waterhouse, Peter M. (2006). RNA interference-inducing hairpin RNAs in plants act through the viral defence pathway. Embo Reports, 7 (11), 1168-1175. doi: 10.1038/sj.embor.7400837

Tomato expression modulating sequences enhance double strand RNA-mediated resistance to potato virus Y in transgenic tobacco

Brosnan, C. A., Mitter, N., Reyes, M., Constantin, M., Graham, M., Dietzgen, R.G. and Carroll, B. J. (2003). Tomato expression modulating sequences enhance double strand RNA-mediated resistance to potato virus Y in transgenic tobacco. 24th Annual Conference on the Organisation and Expression of the Genome, Lorne, Victoria, Australia, 16-20 February, 2003.

Molecular genetic analysis of the two Defective embryo and meristems (DEM) genes in Arabidopsis

Brosnan, C. A., Matthew, L., Reyes, M., Ramage, C. and Carroll, B. J. (2002). Molecular genetic analysis of the two Defective embryo and meristems (DEM) genes in Arabidopsis. The Genome Conference, Lorne, 17-21 February, 2002.

Molecular genetic analysis of the two Defective embryo and meristems (Dem) genes in Arabidopsis

Ramage, C. M., Brosnan, C. A., Matthew, L., Reyes, M. and Carroll, B. J. (2002). Molecular genetic analysis of the two Defective embryo and meristems (Dem) genes in Arabidopsis. XIth International Association for Plant Tissue Culture and Biotechnology Congress, Orlando, USA, 23-28 June, 2002.