The University of Queensland

Towards Understanding Neurodegenerative Diseases: Insights from Caenorhabditis elegans

Wu, Yingjie, Chen, Yining, Yu, Xiaochun, Zhang, Minxing and Li, Zhaoyu (2024). Towards Understanding Neurodegenerative Diseases: Insights from Caenorhabditis elegans. International Journal of Molecular Sciences, 25 (1) 443, 443. doi: 10.3390/ijms25010443

A C. elegans neuron both promotes and suppresses motor behavior to fine tune motor output

Li, Zhaoyu, Zhou, Jiejun, Wani, Khursheed A., Yu, Teng, Ronan, Elizabeth A., Piggott, Beverly J., Liu, Jianfeng and Xu, X.Z. Shawn (2023). A C. elegans neuron both promotes and suppresses motor behavior to fine tune motor output. Frontiers in Molecular Neuroscience, 16 1228980, 1228980. doi: 10.3389/fnmol.2023.1228980

Neuronal motifs reveal backbone structure and influential neurons of neural network in C. elegans

Liu, Jian, Yuan, Ye, Zhao, Peng, Gu, Xiao, Huo, Hong, Li, Zhaoyu and Fang, Tao (2023). Neuronal motifs reveal backbone structure and influential neurons of neural network in C. elegans. Journal of Complex Networks, 11 (3) cnad013. doi: 10.1093/comnet/cnad013

A GNN-based model for capturing spatio-temporal changes in locomotion behaviors of aging C. elegans

Yuan, Ye, Xin, Kuankuan, Liu, Jian, Zhao, Peng, Lu, Man Pok, Yan, Yuner, Hu, Yuchen, Huo, Hong, Li, Zhaoyu and Fang, Tao (2023). A GNN-based model for capturing spatio-temporal changes in locomotion behaviors of aging C. elegans. Computers in Biology and Medicine, 155 106694, 1-10. doi: 10.1016/j.compbiomed.2023.106694

Surface hydrophilicity modification of thin-film composite membranes with metal−organic frameworks (MOFs) Ti-UiO-66 for simultaneous enhancement of anti-fouling property and desalination performance

Wang, Yi (Alex), Smith, Stefan J.D., Liu, Yue, Lu, Peng, Zhang, Xiwang, Ng, Derrick and Xie, Zongli (2022). Surface hydrophilicity modification of thin-film composite membranes with metal−organic frameworks (MOFs) Ti-UiO-66 for simultaneous enhancement of anti-fouling property and desalination performance. Separation and Purification Technology, 302 122001. doi: 10.1016/j.seppur.2022.122001

Change of motifs in C. elegans reveals developmental principle of neural network

Liu, Jian, Yuan, Ye, Zhao, Peng, Liu, Gaofeng, Huo, Hong, Li, Zhaoyu and Fang, Tao (2022). Change of motifs in C. elegans reveals developmental principle of neural network. Biochemical and Biophysical Research Communications, 624, 112-119. doi: 10.1016/j.bbrc.2022.07.108

Chemosensation: Corollary discharge filters out self-generated chemical cues

Li, Zhaoyu and Xu, Shawn X.Z. (2022). Chemosensation: Corollary discharge filters out self-generated chemical cues. Current Biology, 32 (14), R788-R790. doi: 10.1016/j.cub.2022.06.021

Fixed point attractor theory bridges structure and function in C. elegans neuronal network

Liu, Jian, Lu, Wenbo, Yuan, Ye, Xin, Kuankuan, Zhao, Peng, Gu, Xiao, Raza, Asif, Huo, Hong, Li, Zhaoyu and Fang, Tao (2022). Fixed point attractor theory bridges structure and function in C. elegans neuronal network. Frontiers in Neuroscience, 16 808824, 808824. doi: 10.3389/fnins.2022.808824

A graph network model for neural connection prediction and connection strength estimation

Yuan, Ye, Liu, Jian, Zhao, Peng, Wang, Wei, Gu, Xiao, Rong, Yi, Lai, Tinggeng, Chen, Yuze, Xin, Kuankuan, Niu, Xin, Xiang, Fengtao, Huo, Hong, Li, Zhaoyu and Fang, Tao (2022). A graph network model for neural connection prediction and connection strength estimation. Journal of Neural Engineering, 19 (3) 036001, 1-12. doi: 10.1088/1741-2552/ac69bd

Fusogen-mediated neuron−neuron fusion disrupts neural circuit connectivity and alters animal behavior

Giordano-Santini, Rosina, Kaulich, Eva, Galbraith, Kate M., Ritchie, Fiona K., Wang, Wei, Li, Zhaoyu and Hilliard, Massimo A. (2020). Fusogen-mediated neuron−neuron fusion disrupts neural circuit connectivity and alters animal behavior. Proceedings of the National Academy of Sciences, 117 (37), 201919063-23065. doi: 10.1073/pnas.1919063117

Parallel processing of two mechanosensory modalities by a single neuron in C.elegans

Tao, Li, Porto, Daniel, Li, Zhaoyu, Fechner, Sylvia, Lee, Sol Ah, Goodman, Miriam B., Xu, X.Z. Shawn, Lu, Hang and Shen, Kang (2019). Parallel processing of two mechanosensory modalities by a single neuron in C.elegans. Developmental Cell, 51 (5), 617-631. doi: 10.1016/j.devcel.2019.10.008

A Cold-Sensing Receptor Encoded by a Glutamate Receptor Gene

Gong, Jianke, Liu, Jinzhi, Ronan, Elizabeth A., He, Feiteng, Cai, Wei, Fatima, Mahar, Zhang, Wenyuan, Lee, Hankyu, Li, Zhaoyu, Kim, Gun-Ho, Pipe, Kevin P., Duan, Bo, Liu, Jianfeng and Xu, X. Z. Shawn (2019). A Cold-Sensing Receptor Encoded by a Glutamate Receptor Gene. Cell, 178 (6), 1375-1386.e11. doi: 10.1016/j.cell.2019.07.034

The THO complex coordinates transcripts for synapse development and dopamine neuron survival

Maeder, Celine I., Kim, Jae-Ick, Liang, Xing, Kaganovsky, Konstantin, Shen, Ao, Li, Qin, Li, Zhaoyu, Wang, Sui, Xu, X. Z. Shawn, Li, Jin Billy, Xiang, Yang Kevin, Ding, Jun B. and Shen, Kang (2018). The THO complex coordinates transcripts for synapse development and dopamine neuron survival. Cell, 174 (6), 1436-1449.e20. doi: 10.1016/j.cell.2018.07.046

MicroRNA regulation of nAChR expression and nicotine-dependent behavior in C. elegans

Rauthan, Manish, Gong, Jianke, Liu, Jinzhi, Li, Zhaoyu, Wescott, Seth A., Liu, Jianfeng and Xu, X. Z. Shawn (2017). MicroRNA regulation of nAChR expression and nicotine-dependent behavior in C. elegans. Cell Reports, 21 (6), 1434-1441. doi: 10.1016/j.celrep.2017.10.043

An elegant circuit for balancing risk and reward

Li, Zhaoyu, Iliff, Adam J. and Xu, X. Z. Shawn (2016). An elegant circuit for balancing risk and reward. Neuron, 92 (5), 933-935. doi: 10.1016/j.neuron.2016.11.041

CGMP signalling mediates water sensation (hydrosensation) and hydrotaxis in Caenorhabditis elegans

Wang, Wei, Qin, Li-Wei, Wu, Tai-Hong, Ge, Chang-Li, Wu, Ya-Qian, Zhang, Qiang, Song, Yan-Xue, Chen, Yuan-Hua, Ge, Ming-Hai, Wu, Jing-Jing, Liu, Hui, Xu, Yao, Su, Chun-Ming, Li, Lan-Lan, Tang, Jing, Li, Zhao-Yu and Wu, Zheng-Xing (2016). CGMP signalling mediates water sensation (hydrosensation) and hydrotaxis in Caenorhabditis elegans. Scientific Reports, 6 (1) 19779. doi: 10.1038/srep19779

Glial expression of the Caenorhabditis elegans gene swip-10 supports glutamate dependent control of extrasynaptic dopamine signaling

Hardaway, J. Andrew, Sturgeon, Sarah M., Snarrenberg, Chelsea L., Li, Zhaoyu, Xu, X. Z. Shawn, Bermingham, Daniel P., Odiase, Peace, Spencer, W. Clay, Miller, David M., III, Carvelli, Lucia, Hardie, Shannon L. and Blakely, Randy D. (2015). Glial expression of the Caenorhabditis elegans gene swip-10 supports glutamate dependent control of extrasynaptic dopamine signaling. Journal of Neuroscience, 35 (25), 9409-9423. doi: 10.1523/JNEUROSCI.0800-15.2015

Off-response in ASH neurons evoked by CuSO4 requires the TRP channel OSM-9 in Caenorhabditis elegans

Wang, Wei, Xu, Zi-Jing, Wu, Ya-Qian, Qin, Li-Wei, Li, Zhao-Yu and Wu, Zheng-Xing (2015). Off-response in ASH neurons evoked by CuSO4 requires the TRP channel OSM-9 in Caenorhabditis elegans. Biochemical and Biophysical Research Communications, 461 (3), 463-468. doi: 10.1016/j.bbrc.2015.04.017

Encoding of both analog- and digital-like behavioral outputs by one C. Elegans interneuron

Li, Zhaoyu, Liu, Jie, Zheng, Maohua and Xu, X. Z. Shawn (2014). Encoding of both analog- and digital-like behavioral outputs by one C. Elegans interneuron. Cell, 159 (4), 751-765. doi: 10.1016/j.cell.2014.09.056

PKG and NHR-49 signalling co-ordinately regulate short-term fasting-induced lysosomal lipid accumulation in C. elegans

Huang, Wen-ming, Li, Zhao-yu, Xu, Yan-jun, Wang, Wei, Zhou, Mao-ge, Zhang, Peng, Liu, Ping-sheng, Xu, Tao and Wu, Zheng-xing (2014). PKG and NHR-49 signalling co-ordinately regulate short-term fasting-induced lysosomal lipid accumulation in C. elegans. Biochemical Journal, 461 (3), 209-520. doi: 10.1042/BJ20140191

Development of an integrated microfluidic device for evaluating of in vivo chemo-sensing of intact Caenorhabditis elegans

Wang, Jingjing, Li, Zhaoyu, Xu, Zijing, Hu, Liang, Feng, Xiaojun, Chen, Maorong, Du, Wei, Wu, Zhengxing, Luo, Qingming, Xu, Tao and Liu, Bi-Feng (2013). Development of an integrated microfluidic device for evaluating of in vivo chemo-sensing of intact Caenorhabditis elegans. Sensors and Actuators B: Chemical, 178, 343-349. doi: 10.1016/j.snb.2012.12.102

Dissecting a central flip-flop circuit that integrates contradictory sensory cues in C. elegans feeding regulation

Li, Zhaoyu, Li, Yidong, Yi, Yalan, Huang, Wenming, Yang, Song, Niu, Weipin, Zhang, Li, Xu, Zijing, Qu, Anlian, Wu, Zhengxing and Xu, Tao (2012). Dissecting a central flip-flop circuit that integrates contradictory sensory cues in C. elegans feeding regulation. Nature Communications, 3 (1) 776, 776. doi: 10.1038/ncomms1780

A novel fluorescent timer based on bicistronic expression strategy in Caenorhabditis elegans

Chen, Mao-Rong, Yang, Song, Niu, Wei-pin, Li, Zhao-Yu, Meng, Ling-Feng and Wu, Zheng-Xing (2010). A novel fluorescent timer based on bicistronic expression strategy in Caenorhabditis elegans. Biochemical and Biophysical Research Communications, 395 (1), 82-86. doi: 10.1016/j.bbrc.2010.03.143

Fabrication of size-controllable ultrasmall-disk electrode: monitoring single vesicle release kinetics at tiny structures with high spatio-temporal resolution

Li, Zhao-Yu, Zhou, Wei, Wu, Zheng-Xing, Zhang, Rong-Ying and Xu, Tao (2009). Fabrication of size-controllable ultrasmall-disk electrode: monitoring single vesicle release kinetics at tiny structures with high spatio-temporal resolution. Biosensors and Bioelectronics, 24 (5), 1358-1364. doi: 10.1016/j.bios.2008.07.073