Professor Peter Nestor

Professor in Neuroscience

Queensland Brain Institute

Overview

Prof Nestor joined the Queensland Brain Institute in October/2017 and has a conjoint appointment as a cognitive neurologist at Mater Misericordiae Ltd (Mater Hospital).

His particular interests include understanding the earliest stages of Alzheimer's disease (i.e. before dementia is established); atypical forms of dementia with a particular focus on primary progressive aphasia and dementias related to Parkinson's and Lewy body diseases; and improving differential diagnosis between the major categories of neurodegenerative diseases.

He works on development of neuropsychological tests of cognition, both to accurately track change over time and improve diagnostic accuracy between the major diseases causing dementia. He also uses multi-modal imaging (magnetic resonance imaging [MRI] and positron emission tomography [PET]) to understand the sequence of events occurring in degenerative brain diseases (particularly Alzheimer's disease, frontotemporal dementia, Parkinson's disease, motor neuron disease [ALS], progressive supranuclear palsy [PSP] and corticobasal degeneration [CBD]) and identify novel biomarkers. A major focus of his is on developing novel approaches to MR imaging for single subject pathological diagnoses that can be exported into the everyday clinical setting; recent examples include diffusion tensor imaging to identify PSP and CBD (Sajjadi et al, 2013) and quantitative susceptibility mapping in Parkinson's disease (Acosta-Cabornero et al, 2013).

Research Interests

  • Cognitive neurology
  • frontotemporal lobar degeneration
  • progressive aphasia
  • Alzheimer's disease
  • Neurodegenerative diseases

Qualifications

  • Bachelor of Medicine and Bachelor of Surgery, University of Melbourne
  • Doctor of Philosophy in Medicine, University of Cambridge

Publications

View all Publications

Supervision

  • Doctor Philosophy

  • Doctor Philosophy

  • Doctor Philosophy

View all Supervision

Publications

Book Chapter

  • Nestor, Peter J. (2017). Frontotemporal dementia. Dementia. (pp. 749-758) edited by David Ames, John T. O'Brien and Alistair Burns. Boca Raton, FL, United States: CRC Press. doi: 10.1201/9781315381572

  • Sajjadi, S. A. and Nestor, P. J. (2016). Bedside assessment of cognition. Oxford Textbook of Cognitive Neurology and Dementia. (pp. 105-112) edited by Hussain, M. and Schott, J. M.. Oxford University Press, Oxford, UK: OUP. doi: 10.1093/med/9780199655946.003.0010

  • Nestor, Peter J. and Hodges, John R. (2010). Disturbances of higher cerebral function. Oxford Textbook of Medicine. (pp. 4786-4795) edited by David A. Warrell, Timothy M. Cox and John D. Firth. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/med/9780199204854.003.2441

  • Nestor, Peter J. (2007). Disorders of memory. Neurology and Clinical Neuroscience. (pp. 43-57) edited by Anthony H.V. Schapira. Philadelphia, PA, United States: Elsevier. doi: 10.1016/b978-0-323-03354-1.50008-0

  • Nestor, Peter J. (2007). Neuroimaging and other investigative findings. Frontotemporal Dementia Syndromes. (pp. 134-160) edited by John R. Hodges. Cambridge, United Kingdom: Cambridge University Press. doi: 10.1017/cbo9781316135457.007

Journal Article

Conference Publication

  • Gao, Yang, Xiong, Zhuang, Fazlollahi, Amir, Nestor, Peter, Vegh, Viktor, Pike, G. Bruce, Crozier, Stuart, Liu, Feng and Sun, Hongfu (2023). QSM from the raw phase using an end-to-end neural network. ISMRM Annual Meeting, London, United Kingdom, 7-12 May 2022. Berkeley, CA, United States: International Society for Magnetic Resonance in Medicine. doi: 10.58530/2022/4740

  • Flavell, J., Franklin, C. and Nestor, P. (2022). Fragile X-Associated Neuropsychiatric Conditions (FXANC). RANZCP Congress 2022, Sydney, NSW Australia, 15-19 May 2022. London, United Kingdom: SAGE Publications. doi: 10.1177/00048674221088686

  • Ziegler, Gabriel, Heinzinger, Nils, Metzger, Coraline D., Yakupov, Renat, Bittner, Daniel, Glanz, Wenzel, Spottke, Annika, Brosseron, Frederic, Bürger, Katharina, Fließbach, Klaus, Heneka, Michael T., Laske, Christoph, Nestor, Peter J., Peters, Oliver, Priller, Josef, Ramirez, Alfredo, Schneider, Anja, Speck, Oliver, Teipel, Stefan J., Wiltfang, Jens, Wagner, Michael, Düzel, Emrah and Jessen, Frank (2020). Hippocampal volumetric variability is associated with memory in subjective cognitive decline : Neuroimaging / Optimal neuroimaging measures for early detection. Alzheimer's Association International Conference (AAIC 2020), Online, 27-31 July 2020. Hoboken, NJ, United States: Wiley. doi: 10.1002/alz.043527

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Associate Advisor

    Other advisors:

Completed Supervision